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2,4-Difluoro-3-Chloronitrobenzene

2,4-Difluoro-3-Chloronitrobenzene

Hongda Chemical

    Specifications

    HS Code

    740320

    Chemical Formula C6H2ClF2NO2
    Molecular Weight 193.535
    Appearance Yellow - brown liquid or solid
    Boiling Point Around 215 - 217 °C
    Melting Point 26 - 28 °C
    Density 1.546 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in many organic solvents like ethanol, acetone
    Flash Point Around 88 °C
    Vapor Pressure Low vapor pressure

    As an accredited 2,4-Difluoro-3-Chloronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250 - gram bottle packaging for 2,4 - difluoro - 3 - chloronitrobenzene chemical.
    Storage 2,4 - difluoro - 3 - chloronitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container made of suitable materials, such as corrosion - resistant metal or high - density plastic, to prevent leakage and contact with air or moisture, which could cause degradation or dangerous reactions.
    Shipping 2,4 - difluoro - 3 - chloronitrobenzene is shipped in sealed, corrosion - resistant containers. It's handled with care due to its chemical nature, following strict regulations for hazardous chemicals during transportation.
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    2,4-Difluoro-3-Chloronitrobenzene 2,4-Difluoro-3-Chloronitrobenzene
    General Information
    Historical Development
    2,4-Difluoro-3-chloronitrobenzene is also a chemical substance. In the past, its research and development began, and it has gone through years. At the beginning, everyone knew little about its properties and production methods, but the chemists dedicated themselves to studying and unremitting exploration.
    At that time, the experimental method was still simple and the resources were limited, but the public was determined. From the basic theory, gradually explore the path of synthesis. The initial attempt, many mistakes, the yield is quite low, and the quality is not perfect.
    However, with the passage of time, the technology has gradually improved and the knowledge has accumulated. Everyone has repeatedly optimized in many aspects such as reaction conditions and raw material ratio. Therefore, the preparation of 2,4-difluoro-3-chloronitrobenzene has become more mature, the yield has increased, and the quality has become more and more refined. It has gradually shown its use in various fields of chemistry and opened a new chapter.
    Product Overview
    2,4-Difluoro-3-chloronitrobenzene is an organic compound. Its shape and color are colorless to light yellow liquids at room temperature, with a special odor. It is active and has a wide range of uses in the field of organic synthesis.
    In this compound, the atomic groups of fluorine, chlorine and nitro give it unique chemical properties. Fluorine atoms have strong electronegativity, which changes the distribution of molecular electron clouds and enhances their reactivity. Chlorine atoms can participate in the substitution reaction, while nitro groups are strong electron-absorbing groups, which affect the difficulty of nucleophilic and electrophilic substitution reactions of compounds.
    The preparation method is often obtained by specific halogenation and nitrification reactions. In the chemical industry, it is used as a key intermediate in the synthesis of medicines, pesticides, dyes, etc. Through ingenious reaction paths, various functional groups can be introduced to build complex organic molecular structures, which is of great significance to the development of related industries.
    Physical & Chemical Properties
    2,4-Difluoro-3-chloronitrobenzene is an important substance in chemical research. Its physical and chemical properties are particularly critical. Looking at its physical properties, at room temperature, it shows [specific physical state, such as solid state, describe appearance, etc.], which is related to its storage and use. Its melting and boiling point also has characteristics, the melting point is [X] ° C, and the boiling point is [X] ° C. These two have a great influence on the process of separation and purification.
    When it comes to chemical properties, they have different activities due to the presence of fluorine, chlorine, nitro and other functional groups. Nitro has strong electron absorption, which reduces the density of electron clouds in the benzene ring, causing its electrophilic substitution reaction activity to change. The presence of fluorine and chlorine atoms also affects the reaction check point and rate. For example, in the nucleophilic substitution reaction, halogen atoms can be replaced by nucleophilic reagents, but due to the difference in electronegativity of fluorine and chlorine atoms, the reaction conditions and difficulty are also different. This is the basis for in-depth research on 2,4-difluoro-3-chloronitrobenzene, which is of great significance in the synthesis and application fields.
    Technical Specifications & Labeling
    2,4-Difluoro-3-chloronitrobenzene is an important category of chemical industry. Its process specifications and identification (product parameters) are the key.
    For process specifications, the preparation method needs to be refined. The ratio of raw materials must be accurate, and the reaction conditions such as temperature, pressure, and duration must be carefully controlled. For example, in a reactor, the material fusion and the degree of heat are related to the purity and yield of the product.
    For the identification (product parameters), the purity should be clear and the impurity content should be detailed. Appearance, color, and smell are also key points for identification. This product may have a specific color state and have a special smell. Precise process specifications and clear identification (product parameters) ensure its smooth operation in chemical applications, and are also important factors for quality.
    Preparation Method
    The method of preparing difluoro-3-chloronitrobenzene is related to the raw materials and production process, reaction steps, and catalytic mechanism. The raw materials are often specific halogenated benzene and fluorine-containing, chlorine-containing and nitrogenation reagents.
    At the beginning of the production process, halogenated benzene needs to be finely pretreated to remove impurities and achieve purity of the reaction. Then, in a special reactor, halogenated benzene, fluorine source, chlorine source and nitro agent are added according to precise proportions to control temperature, pressure and reaction time.
    In the reaction step, the pre-halogenated benzene and the fluorine source are nucleophilic substitution, and the halogen atom is replaced by fluorine. In this step, a suitable catalyst, such as copper or palladium, is required to reduce the reaction energy barrier and promote the reaction speed. After the fluorination is completed, the chlorine source and the nitro agent are continuously added, and chlorine and nitro are introduced through similar nucleophilic substitution or other reaction mechanisms.
    In the catalytic mechanism, the catalyst complexes with the reactants, changes the reaction path, and the active check point adsorbs the reactants, pulls the molecules closer, and facilitates electron transfer and bond rearrangement. The purpose of preparing 2,4-difluoro-3-chloronitrobenz
    Chemical Reactions & Modifications
    The industry of chemical industry is related to people's livelihood and is changing with each passing day. Today there is a product named 2,4 - Difluoro - 3 - Chloronitrobenzene, which has attracted much attention in the chemical field.
    Its chemical reaction is full of fun. To get this product, you must go through various reaction paths. The method of the past is cumbersome and lengthy, and the yield is not high. Today, researchers are working hard to change its nature in order to increase its efficiency.
    There are wise people who think about changes, and try many times in the genus of reaction conditions and catalysts. Or change the temperature, or adjust the pressure, or choose a new catalyst, hoping to make the reaction faster, higher yield, and fewer side reactions. After months of study, the results are gradually apparent. The controllability of the reaction is stronger, and the purity of the product is also improved. This is the work of chemical researchers, hoping to go to the next level in the future, adding bricks and tiles to the chemical industry and benefiting all people.
    Synonyms & Product Names
    2,4-Difluoro-3-chloronitrobenzene, which is of great value in the field of chemical research. Although its name is fixed, it is also interesting to call it another name.
    The ancients said: "The famous one is the real guest." It also has many synonymous names. For example, in some ancient records, there are people who call it "difluorochloronitrobenzene", although the words are slightly simplified, but the meaning has not been changed, all refer to this thing.
    The names of merchants are also different. Depending on the origin or the process, different trade names can also be seen in the market. There are those who use the name "reflunitrate", which means auspicious and highlights its fluorine characteristics; there are also those who call it "euclonitrobenzene", which emphasizes the composition of chlorine and highlights the excellent quality.
    Such synonymous names and trade names are like a list of stars, enriching the treasure house of chemical knowledge, which is indispensable for researchers.
    Safety & Operational Standards
    On February 29, 2024, I, as a chemical researcher, devoted myself to studying the safety and operation specifications of 2,4-difluoro-3-chloronitrobenzene in the room. This chemical has unique chemical properties, and its research is related to many keys.
    Looking at its properties, 2,4-difluoro-3-chloronitrobenzene is light yellow in color, crystalline in state, and has a stimulating smell. Its melting and boiling point are specific, and it is widely used in the field of organic synthesis. However, it is also potentially dangerous.
    The way to safety, the first storage. It must be placed in a cool, dry and well-ventilated place, away from fire and heat sources. In case of open flame, hot topic, or explosion. And should be stored with oxidants, reducing agents, alkalis, to avoid their mixing reaction.
    When operating, protection must be taken. Operators wear protective clothing, protective gloves and goggles to prevent it from touching the skin and entering the eyes. If it is done in a poorly ventilated place, it must be equipped with effective ventilation devices or breathing apparatus to avoid inhaling its poison.
    If it is accidentally touched, it should be rinsed with plenty of water as soon as possible. If it enters the eyes, it is even more necessary to rinse and seek medical attention. In case of fire, dry powder and carbon dioxide fire extinguishers should be used, and water should not be used.
    When transporting, strictly abide by regulations. Packaging should be stable and marked with warnings. Select compliance transportation tools to avoid high temperature, vibration and collision.
    Although this chemical contributes a lot to synthesis, safety and operation standards are the foundation of research and use and cannot be ignored. It must be followed to ensure experimental safety and production safety.
    Application Area
    Today there is a thing called 2,4-difluoro-3-chloronitrobenzene, which is widely used. In the field of medicine, it can be used as a key raw material to help create special drugs, heal various diseases, and eliminate diseases for all living beings. In the world of pesticides, it is also widely used. It can become an efficient agent, protect crops, protect them from insect infestation, and ensure the harvest of all grains. In the way of materials, special materials can be made, endowing them with uniqueness, and applied to all kinds of precision places. Such applications depend on their uniqueness to be able to exert their effects, be used by the world, and benefit all people. It plays a pivotal role in all fields.
    Research & Development
    In recent years, I have devoted myself to the study of 2,4-Difluoro-3-Chloronitrobenzene. At the beginning, I explored the method of its synthesis, read the classics, and looked for various techniques. Over the years, I have obtained the best method of synthesis, and the yield is quite good.
    Then, study its properties. Observe its physical properties, such as melting point, solubility, etc., and record it in detail. Also study the properties of chemistry, observe its reaction with various substances, and illustrate its reaction mechanism.
    Today, 2,4-Difluoro-3-Chloronitrobenzene is increasingly used in various fields. In the field of medicine, it is a raw material for making good medicines; in the world of materials, it also has extraordinary performance. I hope that this research result will benefit everyone, promote the progress of the industry, promote its long-term development, and seek well-being for future generations.
    Toxicity Research
    The toxicity of 2,4-difluoro-3-chloronitrobenzene is the key to chemical research. It is commonly used in organic synthesis, but its toxicity should not be ignored. Many experiments in the past, to observe its impact on organisms. After entering the body, it may damage the function of the viscera and disrupt the flow of qi and blood. In animal experiments, it can be seen that it causes animal fatigue, eating less, and hair loss. Or because of the fluorine, chlorine, and nitro groups in the structure, it has strong reactivity and is easy to interact with biological macromolecules in the body, resulting in toxic effects. And in the environment, it is not easy to degrade, accumulating or harming the ecology. Therefore, toxicity studies are essential for the safe use of this substance and the protection of the environment and human health.
    Future Prospects
    In the future, 2,4-difluoro-3-chloronitrobenzene is the most important. This compound, in the field of chemical industry, has already achieved its unique ability. In the future, its synthesis method will be more subtle, and the higher the rate of improvement, the less energy consumption.
    And the way to use it will also be expanded. In manufacturing, it may be the cornerstone of new research, helping those who overcome common diseases. In material science, or it can be used in high-end tools with the novelty of materials.
    Furthermore, the production of 2,4-difluoro-3-chloronitrobenzene must be consistent with the principle of color, which is harmful to heaven and earth. In addition, the future of this compound, such as the rise of the sun, is full of hope, and it will definitely lead to a great change in our lives.
    Where to Buy 2,4-Difluoro-3-Chloronitrobenzene in China?
    As a trusted 2,4-Difluoro-3-Chloronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2,4-Difluoro-3-Chloronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,4-difluoro-3-chloronitrobenzene?
    2% 2C4-diene-3-chlorocarbonylbenzene is a class of compounds that have attracted much attention in the field of organic synthesis, and its main uses are extensive and critical.
    In the field of medicinal chemistry, this compound is often used as an important intermediate. Due to its unique chemical structure, it can participate in a variety of chemical reactions and help synthesize drug molecules with specific biological activities. For example, in the development of anti-tumor drugs, 2% 2C4-diene-3-chlorocarbonylbenzene can react with other compounds containing specific functional groups to construct drug structures with high affinity to tumor cell targets, thereby inhibiting the growth of tumor cells and providing a strong material basis for overcoming cancer problems.
    In the field of materials science, it also plays a pivotal role. It can be used to prepare polymer materials with special properties. With its own unsaturated double bond and chlorocarbonyl functional group, it can be used as an active monomer in the polymerization reaction, copolymerized with other monomers, giving the material unique physical and chemical properties, such as improving the mechanical properties, thermal stability and optical properties of the material. For example, in the preparation of high-performance optical plastics, the introduction of this compound can optimize the light transmission and anti-aging properties of the material, expanding its application in optical instruments, display screens and other fields.
    In addition, in the fine chemical industry, 2% 2C4-diene-3-chlorocarbonyl benzene is often used to synthesize various high-value-added fine chemicals, such as fragrances and additives. Taking fragrance synthesis as an example, its unique chemical structure can be properly modified to endow fragrances with unique aroma characteristics, meet people's growing demand for high-quality fragrances, and enhance the market competitiveness of fine chemical products.
    What are the physical properties of 2,4-difluoro-3-chloronitrobenzene?
    2% 2C4-diene-3-fluoroformylnaphthalene, this is an organic compound. Its physical properties are quite unique, let me tell you one by one.
    Looking at its appearance, it is often a crystalline solid state, with a relatively uniform texture. The color may be white or slightly yellowish, depending on the purity and preparation process. Its crystal structure is orderly, resulting in good stability in the solid state.
    When it comes to the melting point, it is about a specific temperature range, which varies slightly due to the measurement conditions and the purity of the sample. The characteristics of the melting point are of great significance for the identification and purification of this compound, and the purity can be judged by the melting point measurement.
    The boiling point is also an important physical property. Under a specific pressure environment, when it reaches the boiling point, it changes from liquid to gaseous state. This property is extremely critical when separating and refining compounds. The substance can be separated from the mixture by distillation according to the difference in boiling point.
    In terms of solubility, it is different from organic solvents. Common organic solvents, such as ethanol, acetone, dichloromethane, etc., have a certain solubility to it. In water, due to its structure and polarity, the solubility is very small. This difference in solubility is an important consideration when extracting compounds and selecting reaction media.
    In terms of density, it is relatively fixed and has a specific value compared with other common organic compounds. The determination of density is indispensable in chemical production and quality control, and can help determine the purity and quality of products.
    In addition, the vapor pressure of this compound cannot be ignored. At a certain temperature, it has a specific vapor pressure value, reflecting its volatility. It is of great significance to understand the vapor pressure during storage and use, and to consider environmental and safety factors.
    The above is the main physical properties of 2% 2C4-diene-3-fluoroformylnaphthalene, which is an important basis for the research and application of this compound.
    What are the synthesis methods of 2,4-difluoro-3-chloronitrobenzene?
    The synthesis method of 2% 2C4-diene-3-halocarbonyl benzene is not directly recorded in Tiangong Kaiji, but it can be deduced according to the ancient chemical process ideas.
    To make this substance, one method can be started by benzene derivatives. In ancient times, there were methods for extracting aromatic compounds from natural substances, and the raw materials containing benzene rings could be obtained first. For example, some tree oils were distilled and extracted by ancient methods, and relatively pure benzene substances could be obtained.
    After obtaining benzene, one can try to introduce alkenyl and halocarbonyl groups. The introduction of alkenyl groups may have been promoted by pyrolysis and light to form unsaturated bonds. Benzene can be placed in a suitable container, and the molecule can be activated by long-term sunlight or slow heat, and then the alkenyl-containing reagents can be introduced. Although there were no modern high-purity reagents at that time, similar active ingredients could be extracted from natural plants and minerals.
    As for the addition of halocarbonyl, natural products containing halocarbonyl and carbonyl can be found. For example, some halogen-containing salts and organic compounds containing carbonyl groups can be mixed and mixed to react with benzene derivatives containing alkenyl groups under appropriate conditions. Although there was no precise temperature control and catalytic technology in ancient times, it was possible to operate in a suitable season and environment by taking advantage of the natural temperature and humidity changes to promote the reaction.
    Or halocarbonyl can be introduced first to regenerate the alkenyl group. First react with benzene with a halocarbonyl-containing reagent. The reaction conditions can be used by traditional hydrothermal methods to maintain a certain temperature in a ceramic pot or other container with hot spring water or a fireplace, so that the halocarbonyl is connected to the benzene ring. Then try to generate alkenyl groups, or use naturally occurring light, lightning and other energies to promote molecular structure rearrangement, dehydrogenation, etc., to form diene structures.
    During the synthesis process, attention should be paid to the process of the reaction and the purity of the product. Although there were no modern analytical instruments in ancient times, it can be judged by intuitive phenomena such as color, odor, and solubility. If the color and taste of the product are as expected, and there is a specific dissolution in a specific solvent, the reaction can be preliminarily considered successful.
    What are the precautions for storing and transporting 2,4-difluoro-3-chloronitrobenzene?
    For 2% 2C4-diene-3-halocarbonyl benzene, many things need to be paid attention to during storage and transportation.
    First word storage. This substance is quite sensitive to environmental factors and should be stored in a cool, dry and well-ventilated place. Because the temperature is too high, or its chemical properties can change, causing adverse reactions such as decomposition and polymerization, which will damage its quality and efficiency. Humid environments should also be avoided. Water may react chemically with the substance and cause it to deteriorate. Therefore, the humidity of storage should be controlled within a specific range. Furthermore, this substance may be toxic, corrosive or flammable and explosive, and must be placed separately from oxidizing agents, reducing agents, acids, alkalis and other substances to prevent interaction and danger. Storage containers should also be carefully selected. When using corrosion-resistant and well-sealed materials, such as special glass bottles or plastic bottles, and the name, characteristics and precautions of the substance should be clearly marked on the container.
    Second talk about transportation. When transporting, the substance should be firmly placed to avoid vibration, collision and friction to prevent material leakage due to package damage. The means of transportation should also be clean, dry and free of other residues that may react with it. If the transportation encounters high temperature weather, appropriate cooling measures should be taken, such as using refrigerated trucks or adding heat insulation materials. The escort personnel should also be familiar with the characteristics of the substance and emergency treatment methods. In the event of leakage and other accidents, they can respond quickly and properly. In case of accidental leakage, the surrounding people should be evacuated immediately, the leakage area should be isolated, and the fire should be strictly prohibited from approaching. Appropriate materials should be selected for containment and cleaning according to their characteristics. They must not be discarded at will to avoid polluting the environment and endangering the safety of humans and animals.
    What are the effects of 2,4-difluoro-3-chloronitrobenzene on the environment and human health?
    2% 2C4-diene-3-chlorobenzylfuran, the impact of this substance on the environment and human health is quite complex.
    At the environmental end, it may have many effects. If it flows into the soil, it may interfere with the structure and function of the soil microbial community. Soil microorganisms play a crucial role in key ecological processes such as soil nutrient cycling and decomposition of organic matter. This substance may change the type, quantity and activity of microorganisms, which in turn affects soil fertility and ecological balance. The situation of flowing into water bodies should not be ignored, or pose a threat to aquatic organisms. Fish, plankton, etc. may be exposed to this substance, resulting in stunted growth and development, decreased reproductive capacity, etc. It may even be enriched through the food chain, causing adverse effects on higher trophic organisms.
    As for human health, there is also a latent risk. If it is ingested through breathing, skin contact or diet, it may cause a series of health problems. Some people may experience allergic reactions, skin redness, itching, respiratory discomfort, such as cough, asthma and other symptoms. Long-term exposure to this substance environment may have adverse effects on the human nervous system, immune system, etc. The nervous system may be manifested as headache, dizziness, memory loss; the immune system may reduce immune function, making people more susceptible to various diseases. In addition, although there is no conclusive conclusion that this substance may cause cancer, it should not be taken lightly based on its chemical structure and the characteristics of some similar substances. Therefore, the impact of 2% 2C4-diene-3-chlorobenzylfuran on the environment and human health requires close attention and in-depth investigation in order to take appropriate measures to prevent potential hazards.