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2,4-Difluoro-1-Nitrobenzene

2,4-Difluoro-1-Nitrobenzene

Hongda Chemical

Specifications

HS Code

369816

Chemical Formula C6H3F2NO2
Molar Mass 159.09 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 196 - 198 °C
Melting Point 12 - 14 °C
Density 1.436 g/cm³ at 25 °C
Flash Point 80 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Vapor Pressure Low vapor pressure at room temperature
Odor Characteristic odor

As an accredited 2,4-Difluoro-1-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250 - gram bottle of 2,4 - difluoro - 1 - nitrobenzene, tightly sealed for safe storage.
Storage 2,4 - difluoro - 1 - nitrobenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly sealed container to prevent leakage. Store it separately from oxidizing agents, reducing agents, and incompatible substances. Use storage facilities compliant with safety regulations to ensure chemical stability and safety.
Shipping 2,4 - difluoro - 1 - nitrobenzene is shipped in sealed, corrosion - resistant containers. It's handled with care due to its chemical nature, transported via approved carriers following strict hazardous materials shipping regulations.
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2,4-Difluoro-1-Nitrobenzene 2,4-Difluoro-1-Nitrobenzene
General Information
Historical Development
In the past, the study of chemical substances has gradually flourished in the world. 2,4-Difluoro-1-nitrobenzene, which began to appear in the eyes of researchers, has also been delayed by years.
At the beginning, scholars observed its clues in the micro-images and explored its nature, but their understanding was still shallow. As time goes by, researchers are unremitting, thinking hard, and its structure and characteristics are becoming clearer.
Every new technology is developed, it is used in this material. Or analyze the wonders of its ingredients, or explore the rules of its reaction. All kinds of efforts have made the understanding of 2,4-difluoro-1-nitrobenzene from ignorance to clarity.
In the field of chemical industry, its use is becoming more and more extensive, either as a raw material or as a reaction, which affects the daily growth. Thanks to the efforts of researchers, the historical evolution of this thing has changed from simple to complex, leaving a deep imprint on the road of science, laying the foundation for future research.
Product Overview
2,4-Difluoro-1-nitrobenzene is also an organic compound. Its shape is colorless to light yellow liquid with a special odor. The melting point of this substance is clear, the melting point is about [specific melting point value], and the boiling point is about [specific boiling point value].
Preparation method is often obtained by specific fluorine substitution reaction and nitrification reaction. During the reaction process, various conditions such as temperature, proportion of reactants and reaction time need to be strictly controlled to increase the purity and yield of the product.
2,4-Difluoro-1-nitrobenzene has a wide range of uses. In the field of pharmaceutical synthesis, it is an intermediate for the preparation of specific drugs; in the field of materials science, it can be used to synthesize materials with special properties. However, it has certain toxicity and irritation. When operating, strict safety procedures must be followed and protective measures must be taken to ensure the safety of the experimenter and the harmlessness of the environment.
Physical & Chemical Properties
2,4-Difluoro-1-nitrobenzene is also an organic compound. It has unique physical and chemical properties. Looking at its physical properties, at room temperature, it is mostly liquid, transparent in color and has a slightly special smell. The values of its boiling point and melting point are the keys to characterize its physical state. Chemically, due to the groups containing fluorine and nitro groups, the properties are active. Fluorine atoms have strong electronegativity, which makes molecular electron clouds different, while nitro groups are strong electron-absorbing groups, making them easy to participate in nucleophilic substitution and other reactions. This compound has a wide range of uses in the field of organic synthesis and can be used as an intermediate to prepare a variety of fine chemicals. The study of its physical and chemical properties is of great benefit to the development of the chemical industry.
Technical Specifications & Labeling
Nowadays, there is a product called 2,4-difluoro-1-nitrobenzene, which is quite important in the field of chemical industry. Its process specifications and identification (product parameters) are the focus of our research.
Looking at its process specifications, the selection of raw materials must be carefully selected, and impurities should not be stored to ensure the purity of the product. When reacting, temperature and pressure are critical, and there should be no slight difference. Control the temperature at a suitable degree to make the reaction go forward and avoid by-products. The pressure should also be appropriate to promote molecular fusion and achieve the expected rate.
As for the identification (product parameters), the appearance should be colorless to light yellow liquid, and the smell should have a specific taste. The purity needs to be extremely high, and the impurity content is minimal. Density, boiling point and other data are recorded in the book as proof of quality. Precise control of process specifications and clear identification (product parameters) can produce high-quality 2,4-difluoro-1-nitrobenzene to meet the needs of all parties.
Preparation Method
The method of preparing 2,4-difluoro-1-nitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. First take an appropriate amount of fluorobenzene as raw material, which is the key starting material. In a special reactor, add an appropriate amount of mixed acid of nitric acid and sulfuric acid, which is the medium and promoter of the reaction.
The temperature is controlled at a suitable range of about 50 to 60 degrees Celsius, which allows the reaction to proceed smoothly and efficiently. Slowly add fluorobenzene dropwise into the mixed acid, and stir while adding dropwise to make the two fully contact. This is the key to the reaction step.
As for the catalytic mechanism, sulfuric acid is not only a reactant here, but also plays a catalytic role, which can reduce the activation energy of the reaction and accelerate the process of hydrogen atoms on nitro-substituted fluorobenzene. After several times of reaction, the reaction liquid is cooled, and the product is purified by separation, distillation, etc. In this way, pure 2,4-difluoro-1-nitrobenzene can be obtained.
Chemical Reactions & Modifications
To taste the wonders of chemical industry, it is related to the change of substances, and 2,4 - Difluoro - 1 - Nitrobenzene, its transformation should be modified, and it is worth studying.
According to the ancient method, it depends on the cooperation of various agents. Under the right temperature and pressure, the bond is easy to transfer. However, the method of the past may not be effective, and the consumption is quite huge.
As for modification, I want to improve its quality and increase its use. In the past, with ordinary techniques, it was difficult to achieve the state of delicacy. Today, we are thinking of a new way to create a method, hoping to make 2,4-Difluoro-1-Nitrobenzene widely used in various fields, such as medicine and materials.
Our researchers should inherit the wisdom of the ancient sages, poor principles, create new methods for chemical application, and seek good strategies for modification, so that this material can be renewed and used by the world, and live up to the responsibility of the researchers.
Synonyms & Product Names
2,4-Difluoro-1-nitrobenzene is also one of the chemical substances. Its synonyms are also called by many names in the industry. Or "2,4-difluoro-nitrobenzene", which is a more common common name, concise and clear, easy to pass on orally. Also known as "4-nitro-1,3-difluorobenzene", it is called according to the name of its molecular structure. Although it is slightly complicated, it is of special significance in accurately describing its chemical structure.
Business names also have their own characteristics. Those that stand out for their characteristics are designed to show their unique uses and advantages, so that buyers can know their names and uses. All of these are formed by the long-term practical exchanges of industry experts, each carrying relevant information, and playing an important role as a bridge in the exchange, production, and research of the chemical industry to help all parties communicate smoothly and promote the development of chemical-related affairs.
Safety & Operational Standards
Specifications for safety and operation of 2,4-difluoro-1-nitrobenzene
. 2,4-difluoro-1-nitrobenzene is one of the most important substances in chemical products. It is useful in both industrial and industrial fields. However, this material is not special, so it is safe to operate and cannot be ignored.
The first thing to say about safety. 2,4-difluoro-1-nitrobenzene has a certain danger. Its pungent taste, if accidentally inhaled, it may affect the respiratory tract, cough, and cause respiratory distress. And its contact with the skin is easy to cause sensitivity, inflammation, and even invasion of the skin. And if you eat it, it will be even more dangerous, and it can be harmful and life-threatening. Therefore, it is necessary to take comprehensive precautions against this thing. For operation, it is advisable to use protective clothing, wear protective gloves, and masks and blindfolds are also indispensable to prevent accidents.
The second time the operation is done. In terms of storage, it should be placed in a good place where it is dry, dry and clear. It is necessary not to oxidize, and the original can be stored equally, in order to prevent the biochemical reaction and become a waste. When using it, it is necessary to be careful when doing it. It is advisable to use equipment and measure it accurately to avoid damage. If it is out, clean it up immediately to prevent pollution and endanger safety. Operation, the general system must be guaranteed to pass, so as to eliminate harmful waste. Furthermore, the operator is familiar with the operation process and can only work together.
Therefore, 2,4-difluoro-1-nitrobenzene is an important value in chemical research and production, but its safety and operation are of the utmost importance. Workers must follow the rules to ensure personal safety and environmental safety.
Application Area
2,4-Difluoro-1-nitrobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help form a variety of specific drugs and cure various diseases. In the process of pesticide creation, it is also very useful. It can be used as a raw material for new pesticides to prevent pests and ensure the abundance of crops. And in material science, it can also participate in the preparation of special materials, making the materials specific and suitable for many special places. Therefore, 2,4-difluoro-1-nitrobenzene is important in various application fields and is indispensable for chemical research and industrial production.
Research & Development
Modern chemistry has advanced, and many new qualities have emerged. 2,4-difluoro-1-nitrobenzene is becoming more and more important in the field of chemical research. My generation studied it, observed its physical properties, and explored its chemical properties.
At the beginning, I studied its preparation method in detail, and strived for refinement and perfection, hoping to obtain high-purity products. And studied the law of its reaction under different media and conditions, hoping to expand its application.
Today, although I have achieved something, the road ahead is still far away. To make it widely used in materials synthesis, pharmaceutical research and development and other fields, we still need to study unremitting. It is necessary to gather the wisdom of all people, be poor in their reasoning, and be good in their laws, so as to promote the rapid development of this new chemical product for the benefit of future generations.
Toxicity Research
Toxicity of 2,4-difluoro-1-nitrobenzene. This substance is light yellow in color and liquid in shape, and has many applications in the chemical industry.
Viewing its toxicity, it may damage the human viscera. If it enters the body through the skin, the skin may have abnormal conditions, redness, swelling, pain, and frequent allergies. If it enters the respiratory tract, the lungs and organs will bear the brunt, causing respiratory diseases, cough and asthma, and even damage the function of alveoli. And it may have the risk of potential genetic mutagenesis. Long-term exposure, cell mutation, and increased risk of cancer.
Therefore, the study of the toxicity of this substance is essential for protection strategies and environmental safety. Make sure that practitioners are aware of their risks and take proper protective measures to avoid harm and ensure the safety of the surrounding environment.
Future Prospects
Fu 2,4 - Difluoro - 1 - Nitrobenzene is a compound that our generation has dedicated to research. Looking at the present, although it has been obtained, it will still be in a grand and broad realm in the future.
At present, this compound has emerged in various fields, either as the foundation of medicine and pharmaceuticals, or as the source of material creation. However, the progress of science and technology has no end. We hope that in the future we can study its subtlety and expand its application.
In the synthesis method, we hope to be simpler and more efficient, reduce its cost and increase its yield. As for performance, when it is deeply explored, it can shine in different scenarios. Over time, we may be able to use this combination to introduce new trends in science and technology, open up new chapters in the future, and seek well-being for the world. This is the vision of our researchers and the future development depends on this.
Where to Buy 2,4-Difluoro-1-Nitrobenzene in China?
As a trusted 2,4-Difluoro-1-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,4-Difluoro-1-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,4-difluoro-1-nitrobenzene?
2% 2C4-diethyl-1-naphthyl ketone, also known as diethylnaphthyl ketone, its main uses are as follows:
This substance is often used as a key intermediate in the field of chemical synthesis. Due to its special chemical structure, many compounds with specific functions can be derived through various chemical reactions. In the organic synthesis path, it is often the starting material for the construction of more complex organic molecules. With ingenious reaction design, it can be converted into organic materials with unique structures and specific properties, such as some organic functional materials with special optical and electrical properties, which can be applied to frontier fields such as optoelectronic device manufacturing.
Furthermore, in the field of medicinal chemistry, it also plays an important role. It can be used as a key building block for the synthesis of specific drug molecules. With the modification and modification of its structure, it is possible to develop drugs with novel pharmacological activities to deal with various diseases. For example, in the development process of therapeutic drugs for certain diseases, it can provide a basic framework for the synthesis of lead compounds. After further optimization and screening, it is expected to become an effective drug for the treatment of related diseases.
In the fragrance industry, it also has its uses. Due to its unique odor characteristics, it can be blended into the fragrance formula to endow the fragrance with a unique flavor, enrich the aroma level of the fragrance, and enhance the quality and uniqueness of the fragrance products, so as to apply it to perfumes, cosmetics, daily necessities, and other fragrant products, adding to the attractiveness and added value of the products.
What are the physical properties of 2,4-difluoro-1-nitrobenzene?
2% 2C4-diethyl-1-naphthyl methanol, this is an organic compound. Its physical properties are as follows:
In appearance, it often takes the shape of white to light yellow crystalline powder, which is easy to observe and handle. In many chemical reactions and industrial applications, this appearance characteristic is conducive to judging its purity and reaction process.
In terms of melting point, it is about a specific temperature range. The melting point is an important physical constant of the substance. This can be used to preliminarily identify the compound and also help to control its temperature conditions during heating or melting-related operations to ensure the smooth progress of experiments or production.
In terms of solubility, it exhibits certain solubility in common organic solvents such as ethanol and ether, but poor solubility in water. This property is of great significance in the separation, purification and solution preparation of compounds. According to their solubility differences, suitable solvents can be selected to achieve the purpose of separation or preparation of specific concentration solutions.
Density has a corresponding value. The physical property of density is crucial for considering the distribution of the substance in the mixed system and participating in some calculations involving volume and mass relationships.
Stability level is relatively stable under conventional environmental conditions. When encountering specific chemical substances such as strong oxidants, strong acids, and strong bases, chemical reactions may occur, causing changes in their structure and properties. Therefore, during storage and use, full attention should be paid to avoid contact with these substances to maintain the stability of their chemical structure and properties.
Is the chemical properties of 2,4-difluoro-1-nitrobenzene stable?
2% 2C4-diene-1-naphthylbenzene, this is an organic compound. As for whether its chemical properties are stable, many factors need to be considered.
From the perspective of molecular structure, the compound contains conjugated diene structure and naphthyl and phenyl groups. The conjugated diene structure gives it unique electron delocalization properties, which can increase its stability to a certain extent. Because electron delocalization can disperse the energy of the system, the molecule is more stable.
However, this conjugated system also gives the compound high reactivity. Conjugated dienes are prone to Diels-Alder reaction, etc., and can form new cyclic compounds with dienophiles. This reactivity may suggest that its chemical properties are not extremely stable.
Furthermore, naphthyl and phenyl are aromatic hydrocarbons, which are aromatic, and the aromatic system is relatively stable due to electron cloud delocalization. However, electrophilic substitution reactions can occur on aromatic rings, and if suitable electrophilic reagents are encountered, they will also react, which affects their stability.
And the stability of this compound varies under different environments. When there is high temperature, light or a specific catalyst, or reactions such as decomposition and rearrangement occur, the stability is reduced. In a low temperature, dark and non-active reagent environment, it may remain relatively stable.
In summary, the chemical stability of 2% 2C4-diene-1-naphthylbenzene is not absolute, depending on the specific environment and reaction conditions, and it cannot be generalized as stable or unstable.
What are the synthesis methods of 2,4-difluoro-1-nitrobenzene?
The synthesis of 2% 2C4-diene-1-naphthyl propene is a crucial issue in the field of organic synthesis. The synthesis methods are rich and diverse, and each has its own advantages. The following are several common methods described in detail.
One of them can be achieved by cross-coupling reaction catalyzed by transition metals. In this method, suitable halogenated naphthalene derivatives and alkenylation reagents are selected, and cross-coupling reactions occur under the catalysis of transition metal catalysts such as palladium and nickel. This process requires fine regulation of reaction conditions, such as temperature, solvent, type and dosage of base, etc. For example, taking a palladium catalyst as an example, palladium acetate is often selected, the solvent can be selected from dichloromethane, N, N-dimethylformamide, etc., and the base can be selected from potassium carbonate, sodium carbonate, etc. After ingenious blending, the reaction is efficiently carried out to obtain the target product. The advantage of this method is that the reaction is highly selective, and the carbon-carbon bond can be accurately constructed, which can effectively improve the purity of the product.
Second, the pyrolysis reaction is also feasible. First prepare a specific structure of the precursor compound, which needs to have the characteristics of being able to rearrange or eliminate the reaction under heating conditions, and then form the target 2% 2C4-diene-1-naphthyl-propylene structure. By precisely controlling the pyrolysis temperature and time, the expected reaction of the precursor compound is promoted. However, this method requires quite high requirements for the design and synthesis of the precursor compound, and a variety of side reactions may occur during the pyrolysis process. The reaction conditions need to be carefully optimized to improve the yield of the target product.
Third, the catalytic synthesis of organic small molecules cannot be ignored. Organic small molecules with specific catalytic activities, such as proline and its derivatives, are used to catalyze reactions between related substrates. Such catalysts are relatively green and environmentally friendly, and in some cases can exhibit unique catalytic properties. The reaction conditions are usually relatively mild, and the requirements for reaction equipment are relatively low. However, finding high-efficiency and selective organic small molecule catalysts is quite challenging, and it needs to be screened and optimized by a large number of experiments.
The above synthesis methods have their own advantages and disadvantages. In practical applications, it is necessary to comprehensively consider the availability of raw materials, reaction costs, purity and yield requirements of the target product, and carefully select the appropriate synthesis path to achieve the efficient synthesis of 2% 2C4-diene-1-naphthyl propene.
What are the precautions for storing and transporting 2,4-difluoro-1-nitrobenzene?
2% 2C4-diene-1-naphthyl acetonitrile is an organic compound. When storing and transporting, the following things should be paid attention to:
First, when storing, it should be placed in a cool, dry and well-ventilated place. This is because the substance may be sensitive to heat and humidity. High temperature and high humidity may cause chemical reactions and even deterioration. If it is in a humid environment, it may cause reactions such as hydrolysis, which will damage its chemical properties.
Second, it is necessary to keep away from fires and heat sources. Because of its flammability, there is a risk of combustion and explosion in case of open flames and hot topics. The storage place should be strictly prohibited from smoking and using open flames, and be equipped with perfect fire protection facilities and equipment.
Third, it should be stored separately from oxidants, acids, bases, etc., and should not be mixed. The chemical properties of this compound determine that it may have violent chemical reactions with the above substances, such as contact with oxidants or severe oxidation reactions, which may cause danger.
Fourth, during transportation, ensure that the container does not leak, collapse, fall, or damage. Because it is a chemical product, once the container is damaged, the material leaks, which may not only cause environmental pollution, but also pose a threat to the safety of transporters and surrounding people.
Fifth, when transporting, you need to follow the specified route and do not stop in densely populated areas and residential areas. This can avoid accidents in densely populated areas and reduce the harm to the lives and property of many people. In the event of a leak during transportation, emergency measures should be taken immediately to evacuate the surrounding population and promptly notify the relevant professional departments to deal with it.