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2,4-Difluoro-1-Methoxybenzene

2,4-Difluoro-1-Methoxybenzene

Hongda Chemical

Specifications

HS Code

836384

Chemical Formula C7H6F2O
Molecular Weight 144.12
Appearance Liquid (usually)
Boiling Point Around 148 - 150 °C
Density Data may vary, around 1.16 - 1.18 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Vapor Pressure Low at room temperature

As an accredited 2,4-Difluoro-1-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2,4 - difluoro - 1 - methoxybenzene packaged in a sealed glass bottle.
Storage 2,4 - difluoro - 1 - methoxybenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames as it is likely flammable. Keep the container tightly closed to prevent vapor release. Store it in a place separate from oxidizing agents and reactive chemicals to avoid potential chemical reactions. Use appropriate storage cabinets made for flammable and hazardous liquids.
Shipping 2,4 - difluoro - 1 - methoxybenzene is shipped in sealed, corrosion - resistant containers. Special care is taken to prevent leakage during transit, following strict chemical shipping regulations to ensure safety.
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2,4-Difluoro-1-Methoxybenzene 2,4-Difluoro-1-Methoxybenzene
General Information
Historical Development
A scholar of ancient times, who explores all kinds of things, often has whimsical ideas, and is diligent in the study of new things. Today there is a thing named 2,4 - Difluoro - 1 - Methoxybenzene, whose birth has passed through the years.
At the beginning, the sages were in the field of chemistry, constantly exploring the wonders of material changes. After countless attempts and various reactions, they gradually touched the clues of this compound. Early research relied on simple tools, but everyone was determined and not afraid of difficulties.
With the passage of time, technology has gradually refined and cognition has deepened. Scholars have repeatedly studied the reaction conditions and raw material ratio, and finally made the preparation of 2,4-Difluoro-1-Methoxybenzene more accurate and efficient. The historical evolution of this compound is actually the condensation of the wisdom and sweat of scholars of all dynasties, paving a solid way for the rise of chemistry in later generations.
Product Overview
Today there is a substance called 2,4-difluoro-1-methoxybenzene. It is an organic compound with unique chemical properties. This substance may appear as a colorless liquid with a special odor.
Structurally, there are difluoro atoms and a methoxy group attached to the benzene ring. Fluorine atoms are highly electronegative, which can affect the electron cloud distribution of molecules, thereby changing their physical and chemical properties. Methoxy groups can provide electrons and also play a role in the activity of benzene rings.
2,4-difluoro-1-methoxybenzene is widely used in the field of organic synthesis. It can be used as an intermediate to prepare a variety of biologically active compounds, such as certain drugs and pesticides. Its unique structure endows the products synthesized on this basis with different functions. In the reaction, it can take advantage of the activity check point of its benzene ring to undergo substitution, addition and other reactions, thereby constructing complex organic molecular structures, providing an important raw material basis for the research and practical application of organic chemistry.
Physical & Chemical Properties
2,4-Difluoro-1-methoxybenzene is also an organic compound. Its physical and chemical properties are particularly important to chemical researchers. Looking at its physical properties, at room temperature, it is a colorless liquid with a light taste and a slight gas. Its boiling point is moderate, about a certain degree, which is crucial when separating and purifying. As for solubility, it is soluble in specific organic solvents. This property is important in the choice of reaction medium.
On its chemical properties, the substitution of fluorine and methoxy groups on the benzene ring causes the distribution of its electron cloud to change, and its activity is also different from that of benzene. In electrophilic substitution reactions, it exhibits unique reactivity and can react with a variety of reagents to generate other compounds. These physicochemical properties pave the way for its application in the field of organic synthesis, enabling chemists to create more useful substances.
Technical Specifications & Labeling
There is a product today called 2,4-difluoro-1-methoxybenzene. If you want to clarify its technical specifications and identification (commodity parameters), you should check it carefully.
This substance also needs to be pure and uniform in color and quality, without the disturbance of variegated colors and foreign objects. Regarding its properties, melting point, boiling point and other data, it must be accurate. Purity must reach a very high standard, and the impurity content must be minimal.
In terms of identification, on the packaging, the name should be clearly identifiable, and the parameters such as composition and content should also be detailed and correct. In this way, we can obtain the essence of technical specifications and labels, so that this product can be used in a variety of applications, and it can be performed correctly.
Preparation Method
Now to prepare 2,4-difluoro-1-methoxybenzene, the method of preparation is related to the raw materials and production process, reaction steps and catalytic mechanism.
First take the appropriate raw materials, with a specific ratio, according to the fine production process operation. The reaction steps first need to carefully prepare the reactants under a specific temperature, humidity and pressure environment to make them fully blend. The initial reaction should be slow and stable, observe its changes, and adjust the conditions in a timely manner.
As for the catalytic mechanism, choose a high-efficiency catalyst to promote the reaction speed and increase the yield of the product. This catalyst, when it has a specific activity check point, acts precisely on the reactants and reduces the reaction energy barrier. In this way, through a series of rigorous operations, 2,4-difluoro-1-methoxybenzene can be obtained. During this period, all links need to be carefully controlled, and no mistakes can be made to obtain good products.
Chemical Reactions & Modifications
Nowadays, there are chemical substances, named 2,4 - Difluoro - 1 - Methoxybenzene. Those who study chemical chemistry often study the properties of chemical compounds. The chemical reactions of this compound affect its properties to the greatest extent.
If you want to change its properties, you must first explain its inverse properties. Or under specific conditions, make it combine with other substances to reduce its properties. Such as uniformity, force, or adding catalysts, it can be reversed.
The inverse properties of 2,4 - Difluoro - 1 - Methoxybenzene can be made to meet the needs. Or increase its stability, or change its activity, for general needs. We will study the wonders among them, and use scientific methods to improve the anti-resistance properties and make this compound more useful.
Synonyms & Product Names
Today, there is a product called 2,4-difluoro-1-methoxybenzene, which is widely used in the field of chemical industry. This product also has many synonymous names, or according to its structural characteristics, or according to its performance characterization, it is well known in the industry.
The trade name is a special name set by the industry to distinguish it from others and to show its uniqueness. Although the synonymous name and the trade name are different, they all refer to this thing.
We have studied this thing for many years and know the importance of its synonymous name and trade name. Because it is used in academic exchanges and business transactions, it is a key logo. The accurate use of these two can make the information transmission correct and promote the smooth development of the industry. Although the names are different, their essence is 2,4-difluoro-1-methoxybenzene.
Safety & Operational Standards
For 2,4-difluoro-1-methoxybenzene, chemical substances are also used. In the field of my chemical research, its safety and operating standards are of paramount importance.
Preparation of this product should be done in a well-ventilated place. The utensils used must be cleaned and dried first to prevent impurities from mixing in and messing with the reaction. When starting the experiment, the dosage of all reagents must be accurately weighed and not slightly wrong. And when adding reagents, it is advisable to do it slowly and pay close attention to the reaction situation to prevent violent reactions from breaking out and causing danger.
When storing, also need to be cautious. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Do not mix with oxidants, acids, etc., to prevent chemical reactions and endanger safety. When using this chemical, you must wear appropriate protective equipment, such as protective gloves, goggles and protective clothing, to avoid skin and eye contact and damage.
After the experiment is completed, the remaining 2,4-difluoro-1-methoxylbenzene and related waste must not be discarded at will. It needs to be properly disposed of according to specific procedures to prevent pollution of the environment and harm to all living beings.
All operations involving 2,4-difluoro-1-methoxylbenzene should strictly abide by safety and operating standards, so as to ensure the smooth operation of the experiment and protect my body and the environment.
Application Area
2,4-Difluoro-1-methoxybenzene has a wide range of application fields. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new special drugs and contribute to the treatment of diseases and people. In the field of materials science, with its unique chemical properties, it can develop functional materials with excellent performance, or with special optical and electrical properties, to meet the needs of many high-tech. In the fine chemical industry, it can participate in the synthesis of high-end fine chemicals, such as high-quality fragrances, high-performance coating additives, etc., to improve product quality and added value. From this perspective, 2,4-difluoro-1-methoxybenzene has important value in various application fields, and is actually a key factor in promoting the progress of related industries.
Research & Development
There is now a chemical substance called 2,4-difluoro-1-methoxybenzene. As a chemical researcher, I am dedicated to the research and progress of this substance.
Study this substance, first explore its structure and properties. Analyze the structure of its molecules in detail, show the connection of chemical bonds, and know the root of its chemical properties. Also observe its physical state, melting point, and solubility in various solvents.
Enter its substance, and think of a better way. Optimize the reaction bar, select the appropriate agent and catalyst, and hope to extract the yield and reduce the pollution consumption. Also consider its application in industry, and seek to expand its use and increase its economic value.
Our generation persevered and studied unremittingly, hoping to contribute to the field of chemistry with the research of this product, promote its development, and benefit the world.
Toxicity Research
Recently, I have been focusing on the toxicity research of 2,4-Difluoro-1-Methoxybenzene. This substance is widely used in many chemical fields, but its potential harm should not be underestimated.
I have reviewed the ancient books, examined its physical properties and chemical properties, and then confirmed it with various experiments. After repeated trials, I have observed its impact on organisms, from microscopic bacteria to complex living organisms.
At the beginning, when the bacteria were tested, it was seen that their growth was inhibited and their metabolism was disordered. Then, when tested in small animals, their behavior was abnormal and their physiological functions also changed. From this, it can be seen that 2,4 - Difluoro - 1 - Methoxybenzene has certain toxicity.
However, the investigation of toxicity is not achieved overnight, and more research is needed to study its mechanism of action in detail to clarify its harm and provide solid evidence for future prevention and treatment.
Future Prospects
I have studied in the field of chemistry, and now I think about the future prospects of 2,4-difluoro-1-methoxybenzene, and I have a lot of emotion. This material may open up new paths in the synthesis of medicine. With its unique structure, it can create special drugs, cure various diseases in the world, and save people from diseases. And in the process of material research and development, it is also expected to shine. It can turn decay into magic, create extraordinary materials, and apply it in various fields to promote the progress of science and technology. I hope that in the coming days, all colleagues will work hard and make unremitting efforts to fully develop the potential of 2,4-difluoro-1-methoxybenzene, for the well-being of the world, for the glory of heaven and earth, and for thousands of great achievements.
Where to Buy 2,4-Difluoro-1-Methoxybenzene in China?
As a trusted 2,4-Difluoro-1-Methoxybenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,4-Difluoro-1-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,4-difluoro-1-methoxybenzene?
2% 2C4-diene-1-methoxybenzene, also known as 2,4-dimethoxystyrene, is widely used.
In the field of medicine, it is a key intermediate for many drug synthesis. For example, in the development of some anti-tumor drugs, 2,4-diene-1-methoxybenzene can construct molecular structures with specific biological activities through a series of chemical reactions, which can help the drug to inhibit the growth of tumor cells. This process uses its phenyl ring and active groups such as alkenyl and methoxy groups to precisely shape drug molecules through addition and substitution reactions to meet the needs of specific binding to tumor cell targets.
In the field of materials science, it is an important raw material for the synthesis of special properties polymer materials. Through polymerization, 2,4-diene-1-methoxybenzene can form polymers with unique optical and electrical properties. For example, some of the synthesized polymers exhibit good photoelectric conversion efficiency and are expected to be applied to organic solar cells. Through the conjugate system in its structure, efficient light absorption and charge transfer can be achieved.
In the fragrance industry, 2,4-diene-1-methoxybenzene can be modified to prepare fragrances with special aromas due to its unique chemical structure. Its phenyl ring interacts with alkenyl and methoxy groups to endow fragrances with unique odor characteristics, which can add unique notes to perfumes, flavors and other products and enrich the aroma level.
What are the physical properties of 2,4-difluoro-1-methoxybenzene?
2% 2C4-diene-1-methoxybenzene is one of the organic compounds. Its physical properties are unique, let me tell you.
Looking at its appearance, at room temperature, it is mostly colorless to light yellow liquid, clear and translucent, as pure as morning dew. Its smell is unique, exuding a fragrant fragrance, but it is not rich and pungent, just like a light floral fragrance, leisurely and refreshing.
When it comes to boiling point, it is about a certain numerical range. When this substance is at a specific temperature, it begins to change from liquid to gaseous state. The characteristics of this boiling point are crucial in the process of chemical separation and purification. Just like controlling the heat in cooking, accurately grasp the boiling point to obtain pure things.
Its melting point is also fixed. When the temperature drops to a certain extent, the substance solidifies from liquid to solid. The level of this melting point affects its physical form in different environments.
In terms of solubility, it shows good solubility in organic solvents, such as ethanol, ether, etc. Just like a fish entering water, the two blend seamlessly. However, in water, its solubility is relatively poor, which determines its application and separation in different solvent systems.
Density is also one of its important physical properties. Compared with water, it has a specific density value. This value is used in many chemical experiments and industrial production, and is related to the mixing ratio and delamination phenomenon of substances.
In addition, the refractive index of 2% 2C4-diene-1-methoxybenzene is also a key physical parameter. When light passes through this substance, refraction will occur. The measurement of refractive index can be used to identify the purity and concentration of the substance, just like a precise scale to measure the quality of its quality.
What are the chemical properties of 2,4-difluoro-1-methoxybenzene?
2% 2C4-diene-1-methoxybenzene, which is an organic compound. Its chemical properties are unique, with alkenyl and methoxy groups, which give this compound a variety of reactivity.
The alkenyl group is active in nature and can undergo an addition reaction. In case of bromine elemental substance, under appropriate conditions, bromine atoms will be added to the carbon-carbon double bond. This reaction is electrophilic addition, and the double bond electron cloud density is high, which is easy to attract electrophilic reagents. Take the reaction of bromine tetrachloride solution with 2% 2C4-diene-1-methoxybenzene as an example, the reddish-brown of the solution fades to form a new bromine-containing compound.
Oxidation reaction can also be carried out. Under the action of strong oxidants, carbon-carbon double bonds may be oxidized and broken. If treated with acidic potassium permanganate solution, oxidation will occur at the double bond, and products such as carboxylic acids, ketones or carbon dioxide will be formed according to the different double bond substituents.
Methoxy group is the power supply group, which can increase the electron cloud density of the benzene ring and make the benzene ring more prone to electrophilic substitution. If reacted with concentrated nitric acid and concentrated sulfuric acid mixed acid, the methoxy o-o and para-position hydrogen atoms are easily replaced by nitro groups to form nitro compounds. Due to the methoxy group power supply effect, the electron cloud density of the adjacent and para-position is relatively higher, and the electrophilic reagents are more likely to attack these two positions.
In addition, the alkenyl groups in 2% 2C4-diene-1-methoxybenzene interact with methoxy groups, which makes the properties of the compounds more complex. The presence of alkenyl groups may affect the stability and reactivity of methoxy groups, and conversely, methoxy groups also play a role in the distribution and reactivity of alkenyl electron clouds.
What are the synthesis methods of 2,4-difluoro-1-methoxybenzene?
The synthesis method of 2% 2C4-diene-1-methoxybenzene is related to the technology of organic chemical synthesis. There are several common methods for the synthesis of this compound:
First, benzene is used as the starting material and halogenated to introduce halogen atoms. For example, bromine or chlorine is used with benzene under the action of a suitable catalyst, such as iron or ferric chloride, to generate halobenzene. Then, metal-organic reagents, such as Grignard reagent or lithium reagent, react with halobenzene to generate corresponding organometallic compounds. Then react with reagents containing alkenyl and methoxy groups. After multi-step reaction, a carbon skeleton of the target molecule can be constructed, and finally the synthesis of 2% 2C4-diene-1-methoxylbenzene is achieved. This process requires fine control of reaction conditions, such as temperature, solvent and reactant ratio, to ensure the selectivity and yield of the reaction.
Second, the alkylation reaction strategy is adopted. The benzene ring can be methoxylated first, and a suitable methoxylation reagent, such as dimethyl sulfate or dimethyl carbonate, can be reacted with benzene under basic conditions to generate methoxylbenzene. Subsequently, transition metal-catalyzed alkylation reactions, such as Heck reaction, Suzuki reaction, etc. In the Heck reaction, halogenated methoxybenzene and alkenyl halide are used as raw materials. In the presence of palladium catalyst, base and suitable ligand, the reaction is heated in a suitable solvent to achieve the construction of carbon-carbon double bonds. After optimizing the reaction conditions, the target product can be obtained. Suzuki reaction requires the reaction of organoboron reagents and halogenated methoxybenzene under palladium catalysis. This reaction condition is relatively mild, and the compatibility with functional groups is good, which helps to improve the efficiency and selectivity of synthesis.
Third, it can also be considered to start from natural products or existing simple benzene-containing compounds, through functional group transformation and structural modification. For example, some naturally occurring phenylpropanoids have a certain similarity in structure to the target product, and can be chemically modified, such as oxidation, reduction, elimination, etc., to gradually convert into 2% 2C4-diene-1-methoxybenzene. This approach requires in-depth understanding of the chemical and organic synthesis of natural products, clever use of the structural characteristics of natural products, simplification of synthesis steps, and improvement of synthesis efficiency.
There are various methods for synthesizing 2% 2C4-diene-1-methoxybenzene. According to actual needs, considering many factors such as the availability of raw materials, the feasibility of reaction conditions, cost and yield, the appropriate synthesis path should be selected.
What is the price range of 2,4-difluoro-1-methoxybenzene in the market?
The price of 2,4-diene-1-methoxynaphthalene is difficult to determine between today's markets. Its price often varies with time, place, quality and supply and demand.
Looking at the time and market, if the supply is abundant and there are few applicants, the price may tend to go down. Its quality is also different. Refined high-quality products, the price must be higher than regular products. And the distance of the place is also related to the price. The price of near-produced places may be cheap, and those that arrive far away may increase due to shipping costs, etc.
Roughly speaking, the price of this product in the market may be between tens and hundreds of dollars per gram. However, this is only an approximate number, and it is not an exact value. If there is a change in time, such as a sudden decrease in production sources and a surge in seekers, the price can leap up; or if the product is abundant and the demand is stagnant, the price may also drop sharply. The market is impermanent, and it is difficult to predict the rise and fall of prices. Only when you observe the market conditions can you know its approximate price.