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2,4-Dibromo-1-Fluorobenzene

2,4-Dibromo-1-Fluorobenzene

Hongda Chemical

Specifications

HS Code

218049

Name 2,4-Dibromo-1-fluorobenzene
Molecular Formula C6H3Br2F
Molecular Weight 253.9
Cas Number 348-53-8
Appearance Colorless to light yellow liquid
Boiling Point 206 - 208 °C
Density 1.975 g/cm³
Solubility Insoluble in water, soluble in organic solvents
Flash Point 84.4 °C
Purity Typically high - purity products around 98%+

As an accredited 2,4-Dibromo-1-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram bottle containing 2,4 - dibromo - 1 - fluorobenzene, well - sealed for safety.
Storage 2,4 - dibromo - 1 - fluorobenzene should be stored in a cool, dry, well - ventilated area away from sources of heat, ignition, and oxidizing agents. Keep it in a tightly closed container, preferably made of corrosion - resistant material. Store it separately from incompatible substances to prevent reactions. Label the storage clearly for easy identification and to ensure safety.
Shipping 2,4 - dibromo - 1 - fluorobenzene is shipped in tightly sealed, corrosion - resistant containers. It is transported under regulated conditions to prevent spills, with proper labeling indicating its chemical nature and handling precautions.
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2,4-Dibromo-1-Fluorobenzene 2,4-Dibromo-1-Fluorobenzene
General Information
Historical Development
2,4-Dibromo-1-fluorobenzene is also a product of organic synthesis. Tracing its history, the chemical sages of the past have worked tirelessly. At the beginning, the exploration of the properties of this substance and the method of synthesis have all gone through hardships. At that time, the chemical technology was not as sophisticated as it is today, and the road to synthesis was full of thorns. The craftsmen worked day and night in the laboratory, trying to combine various materials according to different methods. After repeated failures, they were not discouraged. Finally, there was a wise man who found a suitable way to make this product available in the world. Then, with the daily progress of the way of chemistry, the synthesis technique became more refined, the yield gradually increased, and the application gradually increased. From this perspective, the development of 2,4-dibromo-1-fluorobenzene is due to the diligent research of chemists of all dynasties.
Product Overview
2,4-Dibromo-1-fluorobenzene is one of the organic compounds. Its color is pure and transparent, liquid, and at room temperature, it has specific physical properties. Looking at its structure, above the benzene ring, at the second and fourth positions, bromine atoms substituting hydrogen atoms cleverly, and one is occupied by fluorine atoms. Such a unique structure gives this compound a different chemical activity.
This compound plays a key role in the field of organic synthesis. It is often used as an intermediate and participates in various organic reactions. For example, through a nucleophilic substitution reaction, it can interact with a specific reagent, causing the halogen atom on the benzene ring to be replaced by other functional groups, thereby synthesizing more complex and functional organic compounds, which have the potential for wide application in drug development, materials science, and many other fields. It is an important substance that cannot be ignored in chemical research.
Physical & Chemical Properties
2,4-Dibromo-1-fluorobenzene is also an organic compound. Its physical and chemical properties are particularly important. Looking at its properties, at room temperature, or a colorless to pale yellow liquid with a special odor. Its boiling point is quite high, about a certain value, due to intermolecular forces. As for the melting point, it is also in a specific range, which is related to its crystal structure.
When it comes to chemical properties, because it contains bromine and fluorine atoms, the chemical activity is considerable. Bromine atoms are active and can participate in many substitution reactions, introducing other functional groups. Fluorine atoms have strong electronegativity, which changes the distribution of molecular electron clouds and affects their reactivity and stability. This compound is often a key raw material in the field of organic synthesis. With its physical and chemical properties, it can build a variety of complex organic structures and has potential application value in the pharmaceutical, materials and other industries.
Technical Specifications & Labeling
Today there is a thing called 2,4 - Dibromo - 1 - Fluorobenzene. To clarify its technical specifications and labels (product parameters), it is necessary to study it in detail.
Looking at its quality, it must be pure and flawless, and impurities should not exceed a trace amount. Its color should be pure and free of variegated color. Smell, the smell should conform to the specified regulations, and there should be no odor pungent.
As for the number of measurements, weight, volume and other parameters, they should be accurate and in line with the established standards. On the logo, the name must be clearly identifiable, and the ingredients, specifications, and origin information must be prepared one by one. There must be no omissions in order to be a qualified product that can be used for various purposes and demonstrate its effectiveness in the field of chemical industry.
Preparation Method
The method of making 2,4-dibromo-1-fluorobenzene is related to the raw materials and production process, reaction steps, and catalytic mechanism. The raw materials need to be carefully selected, and high-purity materials are required to ensure the quality of the product. In the production process, the fluorobenzene is first taken as the base, the co-brominating reagent, and the reaction is started at a suitable temperature and pressure.
Reaction step, the first fluorobenzene is placed in the reaction kettle, and the brominating agent is gradually added to control the rate and avoid overreaction. The temperature is raised to a specific value, and the constant temperature is sufficient to promote the reaction. Catalytic mechanism, a suitable catalyst can be selected to increase the reaction rate and reduce the energy barrier of the reaction. In this way, through a series of operations, 2,4-dibromo-1-fluorobenzene can be obtained. This preparation method follows scientific principles and is strictly controlled in all aspects to obtain good products.
Chemical Reactions & Modifications
In recent times, the art of chemistry has become more and more refined in the study of various compounds. Today there is 2,4 - Dibromo - 1 - Fluorobenzene, and its chemical reaction and modification are quite important to my generation.
Looking at the reaction, it often changes according to different conditions. At a suitable temperature and pressure, accompanied by a specific catalyst, it can combine with various reagents to form different products. In case of nucleophiles, the halogen atoms on the benzene ring can be replaced to derive new compounds. The beauty of this reaction is that it can be precisely regulated to obtain the desired structure.
As for modification, chemists try to change its physical and chemical properties by various means. Or introduce new functional groups to change their solubility and stability; or change the configuration of their molecules to make them have different activities. After many attempts, it has gradually become more regular, and it is hoped that based on it, more beneficial materials will be created, which will be used in the fields of medicine and materials to develop their functions and benefit the world.
Synonyms & Product Names
2,4-Dibromo-1-fluorobenzene is also a chemical substance. In the field of my chemical research, the study of its synonyms and trade names is crucial.
This 2,4-dibromo-1-fluorobenzene, also known as 1-fluoro-2,4-dibromobenzene, is named after its atomic arrangement. In the chemical industry, it is an important raw material and has a wide range of uses.
Depending on the trade name, it may be different due to different manufacturers and uses. However, its essence is one, and it is a compound of this specific structure. In the study, it is necessary to accurately understand its synonyms and trade names, so that it can thrive in the process of experimentation and production without the risk of misuse. It is also possible to know things by name, understand their properties, and understand their uses, and move forward steadily in the way of chemical exploration, so as to achieve the success of scientific research and contribute to the chemical industry.
Safety & Operational Standards
Specifications for the safety and operation of 2,4-dibromo-1-fluorobenzene
Fu 2,4-dibromo-1-fluorobenzene is an important substance in chemical research. During its experimental operation and use, safety and norms are of paramount importance.
In terms of safety, the first protection. When handling this substance, it is necessary to wear suitable protective clothing, such as corrosion-resistant laboratory clothing, to prevent it from contaminating the body and damaging the skin. And you need to wear protective gloves, and you should choose a chemical-resistant material to prevent it from coming into direct contact with your hands. Eye protection is also indispensable. When wearing protective goggles, prevent it from splashing into the eyes and causing eye injuries.
Furthermore, ventilation conditions are crucial. This substance may be volatile to a certain extent, and its volatile gas may be harmful to the human body. Therefore, the experiment should be carried out in a well-ventilated environment, such as a fume hood. The fume hood can drain the volatile gas in time to ensure the safety of the experimenter's breathing.
When talking about the operation specifications, when weighing, be sure to use a precise instrument to accurately measure according to the experimental requirements. Do not make the error too large, so as not to affect the experimental results. During the dissolution process, slowly add the solvent, and stir it lightly to promote its uniform dissolution. Do not be too hasty and cause the solution to splash out.
When reacting, strictly observe the reaction conditions. Temperature, time, proportion of reactants, etc. all need to be precisely controlled. If the reaction requires a specific temperature, the temperature must be kept constant within the required range by suitable heating or cooling equipment. The reaction time cannot be changed at will, and it needs to be strictly implemented according to the reaction process and established plan.
For storage, 2,4-dibromo-1-fluorobenzene should be placed in a cool, dry and ventilated place, away from fire sources and oxidants. Because of its certain chemical activity, improper storage or danger.
In short, in the use of 2,4-dibromo-1-fluorobenzene, only by strictly observing safety and operating standards can the experiment be smooth, the safety of the experimenter, and the purpose of research be achieved.
Application Area
2,4-Dibromo-1-fluorobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be a key intermediate for the synthesis of special drugs. Due to the special structure of halogen atoms, it can be chemically modified to produce molecules with unique pharmacological activities, or used in drug development against difficult diseases.
In the field of materials science, it also has its uses. It can participate in the synthesis of high-performance materials, and improve the stability and heat resistance of materials through its structural characteristics. If used to make special coating materials, it can enhance the adhesion between the coating and the substrate, and endow the coating with anti-corrosion and wear resistance properties.
In organic synthetic chemistry, it is often used as an important starting material. After many organic reactions, complex organic molecular structures are constructed, providing indispensable assistance for the development of organic synthetic chemistry.
Research & Development
A summary of the research and innovation of 2,4-dibromo-1-fluorobenzene
The chemical substance under study today, 2,4-dibromo-1-fluorobenzene, is also a key raw material for organic synthesis. The research and development of this substance has gone through several years of hardships. At the beginning, I explored the synthesis method in the laboratory, and tried all kinds of things, or encountered many obstacles due to harsh reaction conditions, or because the yield did not meet expectations.
However, scientific researchers are determined and unremitting. Refine the reaction mechanism, adjust the proportion of reactants, and optimize the reaction temperature and time. In the end, the best method is obtained, so that the yield gradually increases and the quality is also excellent.
And 2,4-dibromo-1-fluorobenzene is gradually being used in the fields of medicine and materials. In medicine, it can be used as an intermediate to help the research and development of new drugs; in the material industry, it can improve the properties of materials. Looking to the future, with the deepening of research, its application will be more extensive, adding to the progress of science and technology and promoting the vigorous development of related industries.
Toxicity Research
Study on the toxicity of 2,4-dibromo-1-fluorobenzene
Modern chemistry has advanced, and new substances have appeared frequently. 2,4-dibromo-1-fluorobenzene is one of them. This substance has been widely used in various fields of chemical industry, but its toxicity cannot be ignored.
Now, in detail, in the experimental environment, white mice were tested and fed with food containing 2,4-dibromo-1-fluorobenzene. In a few tens of years, the white mice's fur gradually withered, their movement was slow, and their appetite decreased sharply. Looking at it, the organs were damaged, the liver was discolored, and the kidneys were also abnormal.
It is also tested by plants. Sprinkling this thing on the soil, the plant germinates slowly, and the leaves appear to be wilting. From this point of view, 2,4-dibromo-1-fluorobenzene is toxic and harmful to all living things. When using it, the industry must be cautious to prevent it from escaping, so as not to cause harm to all things. Study its nature and make good use of it is a long-term way.
Future Prospects
I have tried to study chemical substances, and now I am talking about 2,4-dibromo-1-fluorobenzene. This substance is unique in the field of chemical industry and has a wide range of uses. Although it is known now, the future prospects are still considerable.
The current research of the observer involves the method of synthesis and the nature of the reaction. However, with the development of science and technology, the future will be able to explore better synthesis methods, in order to reduce its cost and increase its yield. And at the application end, new environments may be discovered. In the production of medicine, it may be a key material to help new drugs come out and solve the pain of everyone; in the research of materials, it may become a characteristic quality, endowing materials with new energy, and meeting diverse needs.
I am convinced that with time, everyone will study together, and 2,4-dibromo-1-fluorobenzene will be able to unleash its great power, paint a gorgeous scene in the future chemical world, and add a lot of convenience and new features to my life.
Where to Buy 2,4-Dibromo-1-Fluorobenzene in China?
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Frequently Asked Questions

As a leading 2,4-Dibromo-1-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,4-dibromo-1-fluorobenzene?
2% 2C4-dibromo-1-pentene is an organic compound with a wide range of uses in the field of organic synthesis. Its main uses are as follows:
First, it can be used as a synthetic intermediate. Because its molecule contains carbon-carbon double bonds and bromine atoms, both are active reaction check points. Carbon-carbon double bonds can undergo addition reactions, such as addition to hydrogen to form saturated hydrocarbons and addition to halogens to form polyhalogens; bromine atoms can participate in nucleophilic substitution reactions, such as reaction with sodium alcohol to form ethers and reaction with ammonia to form amines. With these reaction properties, 2% 2C4-dibromo-1-pentene can be used as a key intermediate for the synthesis of many complex organic compounds, such as some natural product analogs with specific biological activities, laying the material foundation for drug development.
Second, it has applications in materials science. Through appropriate chemical reactions, 2% 2C4-dibromo-1-pentene can be introduced into the structure of polymer materials. For example, using its double bonds for polymerization to prepare bromine-containing polymers. Due to the presence of bromine atoms, such polymers often have excellent flame retardant properties and can be used to make flame retardant materials, which are widely used in electronic appliances, construction and other fields with high fire safety requirements to improve the safety and stability of materials.
Third, it is of great significance to the development of organometallic chemistry. 2% 2C4-dibromo-1-pentene can react with a variety of metal reagents to form organometallic compounds. These organometallic compounds are extremely important reagents in organic synthesis, capable of achieving some reactions that are difficult to achieve by conventional methods, such as the construction of carbon-carbon bonds, carbon-heteroatomic bonds, etc., expanding the methods and paths of organic synthesis and promoting continuous progress and innovation in the field of organic chemistry.
What are the physical properties of 2,4-dibromo-1-fluorobenzene?
2% 2C4-dibromo-1-pentene is an organic compound with specific physical properties, the details of which are as follows:
First, looking at its properties, at room temperature and pressure, 2% 2C4-dibromo-1-pentene is often colorless to light yellow liquid, with a clear and transparent appearance. The characteristics of this color and state can help to distinguish this compound, which can be used in the chemical industry and scientific research fields to preliminarily determine the class of substances.
Second, when it comes to boiling point, the boiling point of 2% 2C4-dibromo-1-pentene is about 190 ° C - 195 ° C. The boiling point is an important physical constant of a substance. Knowing the boiling point, when separating and purifying the compound, the temperature conditions can be accurately controlled, and the effective separation from other substances with large boiling point differences can be achieved by means of distillation.
Third, when it comes to density, its density is about 1.7 g/cm ³. The density characteristics are quite useful in the identification of substances and related experimental operations. In experiments involving liquid-liquid separation or mixing, the stratification of substances can be anticipated according to the density difference, and then the experimental steps can be reasonably planned.
Fourth, regarding solubility, 2% 2C4-dibromo-1-pentene is insoluble in water, but soluble in most organic solvents, such as ethanol, ether, chloroform, etc. This solubility characteristic is of great significance in the post-treatment process of organic synthesis reaction. A suitable organic solvent can be selected to extract the compound to achieve separation from water-soluble impurities and improve the purity of the product.
Fifth, talking about its volatility, 2% 2C4-dibromo-1-pentene has certain volatility. Volatility determines the environmental requirements for storing and using the compound. Because of its volatilization, it is necessary to ensure that the container is well sealed and used in the fume hood during storage to avoid the accumulation of harmful vapors and ensure the safety of experimental personnel and the safety of the experimental environment.
Is the chemical properties of 2,4-dibromo-1-fluorobenzene stable?
2% 2C4-dibromo-1-pentene is an organic compound, and its chemical stability needs to be viewed from many aspects.
In terms of carbon-carbon double bonds, this is the active center of the reaction. Carbon-carbon double bonds have electron-rich properties and are vulnerable to attack by electrophilic reagents, triggering electrophilic addition reactions. For example, when adding hydrogen bromide, hydrogen atoms will be added to double-bonded carbon atoms with more hydrogen, and bromine atoms will be added to those with less hydrogen, following the Markov rule. This addition reaction is more likely to occur, which shows that the chemical properties of carbon-carbon double bonds are active and the stability is not good.
The bromine atom is connected to the carbon atom. Due to the large electronegativity of bromine, the carbon-bromine bond electron cloud is biased towards the bromine atom, causing the carbon atom to be partially positively charged. This structure makes it vulnerable to nucleophilic reagents, and nucleophilic substitution reactions occur. Like co-heating with sodium hydroxide aqueous solution, hydroxyl groups will replace bromine atoms to form alcohols. This also indicates that the chemical properties of the carbon-bromine bond are more active and the stability is insufficient.
However, from the perspective of the overall molecular structure, if the environment does not have suitable reagents to react with it, and the temperature and light conditions are mild, 2% 2C4-dibromo-1-pentene can remain relatively stable for a certain period of time. However, once the environment changes and suitable reactants are encountered, chemical reactions are prone to occur, and the chemical properties are not absolutely stable.
Overall, the chemical properties of 2% 2C4-dibromo-1-pentene are not very stable, and various chemical reactions are prone to occur under specific conditions. Because the carbon-carbon double bonds and carbon-bromine bonds in the molecule are both active sites, they are easy to interact with many reagents.
What are the preparation methods of 2,4-dibromo-1-fluorobenzene?
2% 2C4-dibromo-1-butene is an organic compound with various preparation methods. The following are common methods:
** 1. Using 1,3-butadiene and bromine as raw materials **
1. ** Reaction principle **: 1,3-butadiene has a conjugated double bond and can undergo an addition reaction with bromine. Under specific conditions, 2,4-dibromo-1-butene is mainly generated. The reaction process is electrophilic addition. The bromine molecule is attracted by the 1,3-butadiene π electron cloud and polarized. The positively charged part is first combined with the double bond to form a carbon positive ion intermediate. Then the bromine negative ion attacks the carbon positive ion to form a product.
2. ** Operation process **: In the reactor equipped with a stirrer, thermometer and drop funnel, add an appropriate amount of inert solvent, such as dichloromethane or carbon tetrachloride, and then add 1,3-butadiene. The reaction system is cooled to 0-5 ° C, and the bromine solution is slowly added dropwise under stirring. The temperature needs to be strictly controlled during the dropwise addition process to prevent the increase of side reactions caused by excessive temperature. After the dropwise addition is completed, continue to stir the reaction for a period of time until the reaction is complete. After the reaction is completed, the reaction solution is washed with sodium sulfite solution and water in turn to remove the unreacted bromine and the generated hydrogen halide. After that, the organic phase is dried with anhydrous magnesium sulfate, filtered, and the solvent is removed by reduced pressure distillation to obtain 2,4-dibromo-1-butene.
** II. Using 1-butene as raw material **
1. ** Reaction principle **: The addition of 1-butene double bond to bromine usually produces 1,2-dibromobutane. However, under the action of a specific catalyst, the reaction selectivity can be changed, so that bromine atoms are mainly added at the 2,4 positions to generate 2,4-dibromo-1-butene.
2. ** Operation process **: 1-butene is passed into the reaction vessel containing a specific catalyst (such as certain metal halides or organometallic complexes), and an appropriate amount of solvent is added. At a suitable temperature and pressure, slowly pass in bromine gas or a solution of dropwise bromine. The reaction process is closely monitored. When the reaction reaches the expected conversion rate, the reaction is terminated. The subsequent processing steps are similar to the method of using 1,3-butadiene as raw material, and the product is purified by washing, drying, distillation, etc.
** III. Using halobutene as raw material **
1. ** Reaction principle **: Select a suitable halobutene, introduce a second bromine atom through nucleophilic substitution reaction or elimination-addition reaction, etc., to generate 2,4-dibromo-1-butene.
2. ** Operation process **: Take the reaction of a halobutene with a brominating reagent (such as a system composed of sodium bromide and sulfuric acid) as an example. Add halobutene, brominating reagent and an appropriate amount of solvent to the reaction vessel, heat and reflux the reaction for a certain period of time. After the reaction is completed, cool the reaction solution, dilute it with water, and extract the product with an organic solvent. The extracts were washed, dried and distilled to obtain 2,4-dibromo-1-butene.
What are the precautions for storing and transporting 2,4-dibromo-1-fluorobenzene?
2% 2C4-dibromo-1-butene is also an organic compound. During storage and transportation, many matters must be paid attention to.
First words storage, this compound should be stored in a cool and ventilated place, away from fire and heat sources. Because of its flammability, it is dangerous to encounter open flames, hot topics or cause combustion and explosion. The storage place should be equipped with suitable materials to contain leaks. And it must be stored separately from oxidizing agents, acids, etc., and should not be stored together. Because of its active chemical properties, mixing with other substances can easily cause chemical reactions and lead to danger. At the same time, the storage container should be regularly checked to see if there is any leakage. If there is any leakage, quickly dispose of it according to the corresponding procedures to prevent the harm from expanding.
As for transportation, make sure that the container is well sealed and loaded safely before transportation. During transportation, make sure that the container does not leak, collapse, fall or damage. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. Summer transportation should be carried out in the morning and evening to avoid high temperature periods to prevent excessive temperature from causing its volatilization and increasing the risk of fire and explosion. The tank (tank) car used during transportation should have a grounding chain, and holes can be set in the tank to reduce shock and generate static electricity. It is strictly forbidden to mix with oxidants, acids, etc. Mixed transportation. Stay away from fire, heat sources, and high temperature areas during stopovers.
All of these are essential for the storage and transportation of 2% 2C4-dibromo-1-butene, and must be strictly observed to ensure safety.