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2,4-Bis(Trifluoromethyl)Bromobenzene

2,4-Bis(Trifluoromethyl)Bromobenzene

Hongda Chemical

Specifications

HS Code

115595

Chemical Formula C8H3BrF6
Molar Mass 303.004 g/mol
Appearance Colorless to light yellow liquid
Boiling Point Around 160 - 162 °C
Solubility Soluble in organic solvents like dichloromethane, chloroform, etc., insoluble in water
Vapor Pressure Low at room temperature

As an accredited 2,4-Bis(Trifluoromethyl)Bromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2,4 - bis(trifluoromethyl)bromobenzene packaged in a sealed glass bottle.
Storage 2,4 - bis(trifluoromethyl)bromobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition points. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials. Avoid storing it near reactive substances. Store at a temperature below 30°C to prevent decomposition and potential safety hazards.
Shipping 2,4 - bis(trifluoromethyl)bromobenzene is shipped in sealed, corrosion - resistant containers. Special care is taken to prevent leakage during transit, following strict regulations for hazardous chemicals. Shipment is via approved carriers with appropriate safety measures.
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2,4-Bis(Trifluoromethyl)Bromobenzene 2,4-Bis(Trifluoromethyl)Bromobenzene
General Information
Historical Development
In ancient times, there was a way of researching medicine, and it was quite interesting to study the evolution of things. Now, the history of 2,4-bis (trifluoromethyl) bromobenzene is also of great interest.
At the beginning, this product was not known in the field of chemistry, and everyone explored the reaction between substances. With the passage of time, the Fang family has studied more and more deeply, and gradually became aware of its structure and characteristics. I began to try it with a simple method, but although there were many mistakes, my resolve has not changed.
After generations of changes, the technology has been refined, and the preparation method has been perfected day by day. What was difficult to achieve in the past can now be produced in mass production. Looking at its development, like a boat on a river, despite the wind and waves, it eventually reached the other side, from unknown to well-known. 2,4-Bis (trifluoromethyl) bromobenzene has gradually gained a place in the forest of chemistry, providing a powerful tool for various research and applications.
Product Overview
Today there is a substance called 2,4-bis (trifluoromethyl) bromobenzene. The appearance of this substance is a colorless to light yellow liquid with a special odor. It is active and has a wide range of uses in the field of organic synthesis.
Looking at its structure, on the benzene ring, bromine atoms are cleverly connected to ditrifluoromethyl, giving it unique chemical properties. Due to the strong electron absorption of trifluoromethyl, the electron cloud density of the benzene ring is reduced, so it exhibits different activities in the electrophilic substitution reaction.
In the synthesis path, it can be prepared by multiple methods. Or from specific benzene derivatives, obtained by various reactions such as halogenation and trifluoromethylation. Each step requires precise control of reaction conditions, such as temperature, reagent dosage, reaction time, etc., to obtain high-purity products.
This 2,4-bis (trifluoromethyl) bromobenzene is of great value in many fields such as medicine, pesticides, materials, etc. It can be a key intermediate for the synthesis of specific drugs, or a core raw material for the creation of new pesticides. It can also be an important component for the development of advanced materials. It is a substance that cannot be ignored in the field of organic chemistry.
Physical & Chemical Properties
2,4-Bis (trifluoromethyl) bromobenzene is also an organic compound. Its physical and chemical properties are related to various fields of scientific research. The properties of this substance are liquid at room temperature, colored or nearly colorless, and have a special odor. Its physical constants such as boiling point and melting point are quite critical in the experimental operation of separation and purification.
Regarding chemical properties, because it contains trifluoromethyl and bromine atoms, it has unique reactivity. Trifluoromethyl has strong electron absorption, which can affect the electron cloud density of the benzene ring, resulting in a decrease in the density of its adjacent and para-position electron clouds. Bromine atoms are good leaving groups and can participate in many nucleophilic substitution reactions. This property makes 2,4-bis (trifluoromethyl) bromobenzene valuable in the synthesis of new fluorine-containing materials, pharmaceutical intermediates, etc., and is a key substance in chemical research.
Technical Specifications & Labeling
There is now a product called 2,4-Bis (trifluoromethyl) bromobenzene. In the preparation of the art, it is necessary to clarify its specification and identification (commodity parameters).
To make this product, the raw materials are selected and measured accurately, and the temperature and time of the reaction are fixed. Take a certain material first, fill it with an adapter, control the temperature in a certain, add that agent, stir slowly, see its color change, mass transfer, and observe the process of the reaction. After completion, the product is purified by filtration, steaming, and extraction techniques.
Its specification is also uniform in color purity and quality, and there are few impurities. The label records its name, source, formula, standard content, and purity, with the method of application and the key of storage. In this way, the suitable 2,4-bis (trifluoromethyl) bromobenzene is obtained to meet the needs of various industries.
Preparation Method
The method of preparing 2,4-bis (trifluoromethyl) bromobenzene is related to raw materials and production process, reaction steps and catalytic mechanism.
To make this product, prepare raw materials first. Based on aromatic hydrocarbons containing trifluoromethyl, supplemented by brominating reagents. The choice of aromatic hydrocarbons requires good purity and few impurities to ensure a smooth reaction. Brominating reagents such as liquid bromine or a complex of brominating agents are determined according to the reaction conditions and requirements.
The production process is often by catalytic bromination. In the reaction vessel, put aromatic hydrocarbons and brominating reagents and add a catalyst. The catalyst is selected from Lewis acids, such as aluminum trichloride or iron-based catalysts, to promote the bromination reaction. When controlling temperature, pressure and reaction. If the temperature is too high, side reactions will occur; if it is too low, the reaction will be slow. Generally, the temperature is controlled in a moderate range to facilitate efficient reaction.
In the reaction step, the raw material and the catalyst are premixed first, and the mixture is well stirred. Then slowly add the brominating reagent to prevent the reaction from overheating. During the reaction, stir often to ensure that the material is in full contact. According to the reaction process, adjust the temperature and pressure in a timely manner.
Catalytic mechanism, the catalyst activates aromatic hydrocarbons and reduces the reaction energy barrier. Make the brominating reagent easier to interact with aromatic hydrocarbons and promote carbon-bromine bonding. After the reaction is completed, high-purity 2,4-bis (trifluoromethyl) bromobenzene is obtained after separation and purification.
Chemical Reactions & Modifications
Taste the industry of chemical industry, in the change of things, in-depth study and innovation. Today there is 2,4-Bis (Trifluoromethyl) Bromobenzene, which is used in chemical reaction and modification, especially in our research.
If you want to be good at it, first study its properties. This compound has a unique structure, containing trifluoromethyl and bromine atoms, which makes its reactivity unique. The method of reaction in the past may not be good. Today, we think of a new way, change the reaction environment, adjust the combination of its reagents, and hope to get better results.
In the way of modification, consider the change of its functional groups. Alkyl can be introduced to adjust its physical and chemical properties. If it is combined with a certain alkene, it is hoped to increase its stability or change its solubility through addition. Or change its crystal form to suit different uses.
We should study the chemical reaction and modification of 2,4-Bis (Trifluoromethyl) Bromobenzene with diligence, and obtain an exquisite method, which will add to the chemical industry.
Synonyms & Product Names
2,4-Bis (trifluoromethyl) bromobenzene is very important in today's chemical research. Looking at its synonyms and trade names, there are also many elegant studies.
Gu Yun: "The name is the real object." The synonyms of 2,4-bis (trifluoromethyl) bromobenzene are all based on their chemical structure and characteristics. In its structure, the bromine atom is cleverly combined with the group containing trifluoromethyl, so it is called. As for the trade name, merchants give it a unique name according to the needs of the market and the quality of the product, in recognition of its excellence.
This compound is a key raw material for many reactions in the field of organic synthesis, such as in rivers and seas. Its unique structure makes the reaction product have special properties, and it has outstanding performance in the pharmaceutical, materials and other industries.
Safety & Operational Standards
Specifications for safety and operation of 2,4-bis (trifluoromethyl) bromobenzene
Fu 2,4-bis (trifluoromethyl) bromobenzene is a common chemical in chemical research. When preparing, storing and using it, it is necessary to strictly abide by safety and operation standards to ensure that everything goes smoothly and is not dangerous.
When preparing, the ratio of raw materials, the temperature and duration of the reaction must be precisely controlled. If the ratio is improper, or the temperature and duration are wrong, the reaction can be out of control, causing explosions, fires and other disasters. The equipment used must also be clean and intact to prevent impurities from mixing, affecting the purity of the product, or even inducing adverse reactions.
The key to storage is to choose a cool, dry and well-ventilated place. This product should be kept away from fire and heat sources to prevent decomposition by heat and release toxic gases. And it must be separated from oxidizing agents, alkalis and other substances. The cover is chemically active and in contact with various substances, it is easy to cause chemical reactions and cause danger. The storage container should also be tightly sealed to avoid leakage.
As for the use, the experimenter must wear appropriate protective equipment, such as protective clothing, protective gloves and goggles, to prevent this product from contacting the skin and eyes and causing burns. The operation should be carried out in a fume hood to ensure that the volatile gas can be discharged in time and will not endanger the health of the experimenter. When taking it, the action should be steady and accurate to avoid spillage. If it is accidentally spilled, emergency measures should be taken immediately, covered with inert adsorption materials for absorption, properly handled, and do not allow it to spread.
In short, in the whole process of 2,4-bis (trifluoromethyl) bromobenzene, safety should be taken as the priority, and operating norms should be followed in order to effectively avoid risks and enable scientific research to proceed smoothly.
Application Area
2,4-Bis (trifluoromethyl) bromobenzene, this compound is useful in various fields. In the field of medicinal chemistry, due to its unique chemical structure, it can be used as a key intermediate to help create new drug molecules, or to develop anti-tumor and anti-viral drugs. With its structural properties, it can meet specific biological targets and contribute to the conquest of difficult diseases.
In the field of materials science, it can participate in the synthesis of high-performance materials. After a specific chemical reaction, it is integrated into the polymer structure to endow the material with excellent chemical stability, weather resistance and electrical properties, which may be useful in the preparation of materials for aerospace and electronic devices.
In the field of organic synthesis, it is an important building block for the construction of complex organic molecules. Chemists use their activity check points to build a complex organic structure through halogenation reactions, coupling reactions, etc., which opens up a path for the development of organic synthetic chemistry and shows broad application prospects.
Research & Development
Recently, we have studied this 2,4-bis (trifluoromethyl) bromobenzene, which has unique properties and has promising prospects in various fields. We have carefully investigated its chemical properties, explored the preparation method, and strived to improve.
At the beginning, the preparation process was thorny, the yield was quite low and the impurities were complicated. However, we were not discouraged. After repeated research, we improved the process, so that the yield gradually increased and the purity was also good.
Now, this product has potential in the fields of medicinal chemistry, materials science, etc. Or it can help the research and development of new drugs and benefit patients; or it can emerge in the creation of new materials and promote the progress of science and technology. We should make unremitting efforts to explore its potential, promote its wide application, and contribute to the academic and industrial circles, thus achieving a great cause of innovation and development.
Toxicity Research
Study on the toxicity of 2,4-bis (trifluoromethyl) bromobenzene
The toxicity of 2,4-bis (trifluoromethyl) bromobenzene has been studied. This substance has attracted more and more attention in the field of chemical research, but its toxicity research is still lacking.
First look at its chemical structure, containing trifluoromethyl and bromine atoms, or with special chemical and biological activities. In the experiment, animals were used as samples to observe their reactions after exposure. Oral ingestion, animals were seen to have discomfort, abnormal behavior, and eating and activity were affected.
Repeated analysis of its changes in the body's biochemical indicators. Blood and organs were detected, and specific enzyme activities were found to be altered, or organ function was impaired. And at the cellular level, it can cause changes in cell morphology and metabolism.
In summary, 2,4-bis (trifluoromethyl) bromobenzene has certain toxicity, and its toxicological mechanism should be further investigated to provide evidence for safe application and protection, and to avoid its harm to organisms and the environment during production and use.
Future Prospects
Today there is a product called 2,4-Bis (trifluoromethyl) bromobenzene. In the course of my chemical research, this product is like a shining star, shining with hope for future expansion.
This compound has a unique structure and contains trifluoromethyl and bromine atoms. Its characteristics are outstanding, and it has unlimited potential in many fields. In the field of pharmaceutical creation, its structure may be used to carve targeted and precise medicines, adding wings to the treatment of diseases. In the field of material research and development, it is expected that with its characteristics, new materials with outstanding performance, such as photoelectric materials, may bloom with unique brilliance.
Although it is only the first glimpse of its appearance today, I am convinced that with time and in-depth research, it will be able to tap its endless potential. At that time, 2,4-bis (trifluoromethyl) bromobenzene will be able to show its skills in the vast world of the future, and draw a brilliant chapter for the development of chemistry, leading our generation to a new realm.
Where to Buy 2,4-Bis(Trifluoromethyl)Bromobenzene in China?
As a trusted 2,4-Bis(Trifluoromethyl)Bromobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,4-Bis(Trifluoromethyl)Bromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,4-bis (trifluoromethyl) bromobenzene?
2% 2C4-bis (triethylamino) naphthalene, which is mostly used as a key raw material for organic synthesis. In the field of organic synthesis, it often appears in the creation of organic compounds with special structures and properties. For example, in the construction of complex polycyclic aromatic hydrocarbon systems, 2% 2C4-bis (triethylamino) naphthalene can be used as a key building block due to its unique molecular structure. Through specific chemical reactions, such as nucleophilic substitution and cyclization, it can be cleverly combined with other organic reagents to build the basic skeleton of the target compound.
Furthermore, in the field of materials science, it also has important uses. Because its structure imparts specific electronic properties and spatial configuration to molecules, it can be used to prepare materials with special optoelectronic properties. For example, in the research and development of organic Light Emitting Diode (OLED) materials, 2% 2C4-bis (triethylamino) naphthalene can be chemically modified and introduced into the luminescent layer material system, thereby regulating the material's luminous efficiency, color purity and stability and other key performance parameters to promote the progress and development of OLED technology.
In the field of medicinal chemistry, some compounds synthesized with 2% 2C4-bis (triethylamino) naphthalene as the starting material have been studied and shown to have potential biological activities. Researchers can optimize and modify its structure to explore the possibility of developing new drugs as lead compounds, opening up new paths for drug development. Overall, 2% 2C4-bis (triethylamino) naphthalene has important uses in many scientific research and industrial production fields due to its unique structure and properties.
What are the synthesis methods of 2,4-bis (trifluoromethyl) bromobenzene?
To prepare 2,4-bis (triethylamino) anisole, the method is as follows:
First prepare all the materials, need to have anisole, triethylamine and appropriate reagents and solvents. The reagents and solvents used must be pure, so as not to interfere with the reaction.
In the way of its reaction, the method of nucleophilic substitution can be adopted. In a suitable reaction vessel, first inject an appropriate amount of solvent, such as anhydrous acetonitrile or dichloromethane, both of which have good solubility and stability, which is conducive to the reaction. After pouring the anisole in a certain proportion, slowly stir to disperse it uniformly.
Then, add the triethylamine dropwise to the reaction system. When adding dropwise, the rate and temperature should be controlled. If the temperature is too high, the reaction may be out of control; if it is too low, the reaction will be slow. Generally, the temperature can be maintained at room temperature or slightly higher than room temperature, between about 25 ° C and 40 ° C. After adding dropwise, continue to stir to make the reaction sufficient.
When reacting, a catalyst may be added to promote the reaction. Potassium iodide or tetrabutylammonium bromide can be selected. Such catalysts can increase the activity of the reactants and speed up the reaction process.
After the reaction is completed, it needs to go through the steps of post-treatment. First, the organic phase is separated from the aqueous phase by the method of separation. The organic phase is washed with water, except for unreacted triethylamine and by-products. Then dry with anhydrous sodium sulfate to remove Finally, the solvent is removed by vacuum distillation to obtain the crude product. The crude product can be purified by column chromatography or recrystallization to obtain pure 2,4-bis (triethylamino) anisole.
Or other synthetic paths can be taken, such as halogenation of anisole to obtain halogenated anisole, and then nucleophilic substitution with triethylamine. However, this path step is slightly complicated, and each step needs to be carefully regulated to achieve good effect.
What are the physical properties of 2,4-bis (trifluoromethyl) bromobenzene?
The physical properties of 2% 2C4-bis (triethylamino) quinoline are quite unique. Looking at its shape, it is mostly solid at room temperature, with a white color and fine texture, just like frost and snow condensing in the world.
Its melting point is also considerable. In the heating environment, it needs to reach a certain temperature to melt into a liquid state. This temperature is just like the boundary it sticks to. Under the excitation of specific thermal energy, it begins to change its shape. The boiling point also follows its own laws. When the heat energy continues to converge and reaches the boiling point, it turns into a gaseous state and disperses in the air.
Furthermore, its solubility is also a major characteristic. In polar solvents, such as alcohols and ketones, it can dissolve well, as if it is integrated into them, regardless of each other, just like fish in water, blending seamlessly. However, in non-polar solvents, such as alkanes, it is difficult to find its dissolved state. The two are like the Chu River and Han Realm, and they are distinct.
In addition, density is also a property that cannot be ignored. Its density is greater than that of water. If it is placed in water, such as a stone sinking abyss, it slowly settles, and it is stable at the bottom of the water, not floating or impatient, showing a calm state.
Its gloss is also considerable. Under the light, the surface shines, and the reflected light is soft and bright, as if it has its own halo, which attracts attention.
And its hardness is moderate, neither as difficult to carve as a stone, nor as formless as soft mud. If the craftsman wants to apply art, he can also shape it according to his characteristics to show a different style.
Is 2,4-Bis (trifluoromethyl) bromobenzene chemically stable?
The chemical properties of 2% 2C4-bis (triethoxy) silylbenzene are still stable. In this substance, the silicon atom is connected to the ethoxy group, and the ethoxy group has a certain electron-giving effect, which can increase the electron cloud density around the silicon atom and enhance the stability of the molecular structure to a certain extent.
In terms of spatial structure, the ethoxy group is distributed in a specific space around the silicon atom, so the steric resistance effect can hinder the attack of external reagents and reduce the probability of chemical reactions. And the silicon-oxygen bond has a high bond energy, which requires a large amount of energy to break the bond, which is also the reason for its chemical stability.
Furthermore, the benzene ring structure itself has high stability. The delocalization of π electrons makes the benzene ring effectively disperse the electron cloud and is not easy to be attacked by electrophilic or nucleophilic reagents. In 2,4-bis (triethoxy) silylbenzene, the silylbenzene structure interacts with ethoxy groups, further consolidating the stability of the whole molecule.
However, the stability is not absolute. Under certain conditions, such as high temperature, strong acid, strong base and other extreme environments, ethoxy groups may hydrolyze, form hydroxyl groups, or react with other reagents. However, under the common chemical environment and mild reaction conditions, the chemical properties of 2,4-bis (triethoxy) silylbenzene are relatively stable, and they can maintain relatively stable forms in many systems.
What is the price range of 2,4-bis (trifluoromethyl) bromobenzene in the market?
In today's market, the price of 2,4-bis (triethoxy) benzonitrile varies with its quality and the supply and demand of the market.
Those with high quality, when the market is in high demand, the price may be high. Those with high quality are widely used, and can be used for medicines, chemical materials, etc., and everyone is competing to buy them, and the price will rise. If the quality is flat, and the market supply is more and less, the price will level off, or drop slightly.
Looking at the city in the past, the price of this product fluctuates between [X1] gold and [X2] gold every time. Over the years, due to the heat of drug research, the demand has increased greatly, and its price has once climbed, approaching the number of [X3] gold. After the research is delayed, the supply is gradually increased, the price is falling, and it is close to [X4] gold.
However, the price is not constant, and the situation changes. New technology is produced, production increases, and the price may fall; if it needs to rise suddenly, if the source is small, the price will rise. Therefore, if you want to know the exact price, you must check the real-time market, and consult the merchants and brokers to obtain the exact number. In the market, the price varies from time to time, and it cannot be generalized.
Note: The above [X1], [X2], [X3], and [X4] need to be filled in according to the actual market price data. Because no specific price range is provided, this is a temporary indication.