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2,4-Bis(Trifluoromethyl)Benzeneboronic Acid

2,4-Bis(Trifluoromethyl)Benzeneboronic Acid

Hongda Chemical

    Specifications

    HS Code

    504373

    Chemical Formula C8H5BF6O2
    Molecular Weight 270.926
    Appearance White to off - white solid
    Purity Typically high purity, e.g., 97%+
    Melting Point 146 - 150 °C
    Solubility Soluble in some organic solvents like dichloromethane, THF
    Boiling Point Decomposes before boiling
    Density N/A (solid, density less relevant in common use)
    Acidity Weakly acidic due to boronic acid group
    Stability Stable under normal storage conditions, protect from moisture

    As an accredited 2,4-Bis(Trifluoromethyl)Benzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 2,4 - bis(trifluoromethyl)benzeneboronic Acid in a sealed, chemical - resistant package.
    Storage 2,4 - bis(trifluoromethyl)benzeneboronic acid should be stored in a cool, dry place away from heat and ignition sources. Keep it in a tightly sealed container to prevent moisture absorption, as boronic acids can react with water. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions.
    Shipping 2,4 - bis(trifluoromethyl)benzeneboronic acid is shipped in well - sealed containers. It's transported in accordance with hazardous chemical regulations, ensuring proper protection from environmental factors during transit.
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    2,4-Bis(Trifluoromethyl)Benzeneboronic Acid 2,4-Bis(Trifluoromethyl)Benzeneboronic Acid
    General Information
    Historical Development
    About the history of 2,4-bis (trifluoromethyl) phenylboronic acid
    2,4-bis (trifluoromethyl) phenylboronic acid is now a wonderful chemical product. Tracing back to its source, the early chemical sages explored it at the end of the day. At that time, the technology of chemical industry was not as sophisticated as it is today, and the public used their determination and sensitive thinking to find its traces in various reactions.
    At the beginning, everyone's understanding of fluorine-containing compounds was still shallow, and the synthesis method was difficult. The sages have repeatedly tried and erred, but they have not given up. After a long period of research, they gradually got clues to the synthesis of fluorine-containing phenylboronic acids. After countless times of improving the reaction conditions and optimizing the ratio of raw materials, the method of synthesizing 2,4-bis (trifluoromethyl) phenylboronic acid has gradually become complete.
    This product has emerged in the field of medicine, materials and other fields since the present, adding a bright pearl to the chemical technology, and also testifying to the power of exploration and research by many scholars.
    Product Overview
    2,4-Bis (trifluoromethyl) phenylboronic acid is also an important agent in organic synthesis. Its shape may be white to off-white powder, with high purity, often meeting the standards stipulated by many laws. In the field of organic synthesis, this product has a wide range of uses and can involve many reactions, such as Suzuki-Miyaura coupling reaction, which can establish carbon-carbon bonds. It is a key step in creating complex organic structures. Its properties are stable and can be stored for a long time under suitable conditions. The method of synthesis has been studied by generations of chemists and is gradually maturing. However, when preparing, it is necessary to carefully control each step, control temperature, adjust pressure, and select the appropriate agent, in order to obtain high-quality products. Those who use it should also be aware of its nature and abide by the rules of operation to prevent accidents before they can develop their capabilities and promote the progress of organic synthesis.
    Physical & Chemical Properties
    Nowadays, there is a substance named 2,4-bis (trifluoromethyl) phenylboronic acid, whose physical and chemical properties can be investigated. Looking at its shape, or its crystalline state, the color is pure and translucent, which is related to its physical properties. As for chemical properties, boron atoms live in the structure, which makes this substance have unique reactivity. In the field of organic synthesis, it is often a key reagent, and can interact with many compounds containing unsaturated bonds according to a specific mechanism to form new compounds. And its stability is also considerable, under moderate conditions, it can maintain the integrity of the structure. However, in the case of strong acids and bases, or hot topics, its structure may change, causing chemical changes. These are the important physical and chemical properties of 2,4-bis (trifluoromethyl) phenylboronic acid, which are also important for scientific research and industrial applications.
    Technical Specifications & Labeling
    There is now a product called 2,4-Bis (trifluoromethyl) phenylboronic acid. This chemical product, in our field of chemical research, its technical specifications and identification (product parameters) are crucial.
    On its technical specifications, it is necessary to clarify its purity geometry and impurity content, which is related to its performance in various chemical reactions. And its physical properties, such as melting point, boiling point, solubility, etc., cannot be ignored, which are all factors for measuring its quality.
    As for the identification (product parameters), its chemical structure should be listed in detail to prove that it is indeed 2,4-bis (trifluoromethyl) phenylboronic acid. Its molecular weight and molecular formula should also be accurately marked so that users can understand. Only by knowing the technical specifications and identification (product parameters) can we make good use of this material and proceed smoothly in the process of chemical research.
    Preparation Method
    In the process of making 2,4-bis (trifluoromethyl) phenylboronic acid, the raw materials and process are the key. First, take all kinds of combined raw materials and poly them according to a specific ratio. The reaction steps start in a suitable temperature kettle, so that the raw materials are blended, and the precise heat is controlled to promote their slow synthesis. In the meantime, the speed of stirring and the temperature control are all about success or failure.
    When the reaction is gradual, pay attention to its signs and fine-tune the conditions in a timely manner. As for the catalytic mechanism, choose the appropriate catalyst, and use its force to increase the efficiency of the reaction, so that the molecules can be cleverly rearranged and combined. And in the reaction process, observe the changes of each substance in detail, and decide the subsequent steps according to the situation. Therefore, following this rigorous method, it is expected to obtain high-quality 2,4-bis (trifluoromethyl) phenylboronic acid products.
    Chemical Reactions & Modifications
    Recently, this compound of 2,4-Bis (Trifluoromethyl) Benzeneboronic Acid has been studied for its chemical reaction and modification.
    Looking at the reaction of this compound, it was initially based on the conventional method, but the effect was not as expected. Its structure contains trifluoromethyl, which is unique in nature, causing the conventional reaction path to be blocked. Then think about changes, check the books and refer to the old examples, hoping to find a solution.
    Later, it was changed to a mild reagent to adjust the temperature and pressure of the reaction, and it turned around. The reaction gradually stabilized, and the quality and quantity of the product improved. This is a modification of the chemical reaction conditions, which is an unexpected pleasure.
    Also considering the expansion of its application, if it can modify its boron-based part, it may have extraordinary performance in specific fields. Although the road ahead is long, I hope to explore more possibilities of this compound, and continue to move forward in chemical reactions and modifications.
    Synonyms & Product Names
    Recently, a new type of chemical was developed, which is called 2,4-bis (trifluoromethyl) phenylboronic acid. This substance has unique properties and a wide range of uses.
    Looking for its synonyms and trade names, it is like exploring the secret words of ancient books. Its synonyms may have other names, and the trade names are also chosen by each merchant with their own ingenuity.
    My generation is in the laboratory, studying its properties carefully, hoping to expand its use. It is like the ancients searching for treasures, finding the key in the clues. Hope to be able to study its synonyms and trade names in detail, and the academic aid industry will further understand it. Like the ancient sages who have been through their heads and made unremitting efforts to seek the truth. I hope this research can add to the field of chemistry, like the grandeur of ancient buildings, brought together by bits and pieces.
    Safety & Operational Standards
    2,4-Bis (trifluoromethyl) phenylboronic acid, this chemical substance is a top priority for safety and operating practices.
    For storage, be sure to choose a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent accidents. It should be placed separately from oxidants and food chemicals, and must not be mixed to avoid dangerous chemical reactions. The storage area should be equipped with suitable materials to contain possible leaks and prevent them from happening.
    During operation, operators must undergo special training and strictly follow operating procedures. Operators are advised to wear self-priming filter dust masks to prevent inhalation of dust from the substance, causing damage to the respiratory tract; wear chemical safety glasses to protect the eyes from possible damage; wear anti-poison infiltration work clothes to prevent skin contact; wear rubber gloves to enhance protection. Smoking should be strictly prohibited at the operation site to avoid danger caused by open flames. When handling, it should be handled lightly to prevent damage to packaging and containers, resulting in material leakage. In case of accidental leakage, isolate the leaking contaminated area and restrict personnel from entering and leaving. Emergency responders should wear dust masks (full masks), wear gas suits, collect them in a dry, clean, covered container with a clean shovel, and transfer them to a safe place.
    In conclusion, for chemicals such as 2,4-bis (trifluoromethyl) phenylboronic acid, every step from storage to operation requires strict adherence to safety and operating practices, without any slack, in order to ensure that personnel safety and the environment are not endangered.
    Application Area
    2,4-Bis (trifluoromethyl) phenylboronic acid is widely used in the field of chemistry today. It can be used as a key intermediate in the research and development of medicine, helping to create new drugs to treat various diseases. For example, in the development of anti-cancer drugs, with its special structure, it helps drugs to accurately target diseased cells, increasing efficacy and reducing side effects.
    In the field of materials science, it also has outstanding performance. It can be used to prepare special functional materials, such as materials with excellent photoelectric properties, and applied to electronic displays and other devices to make the display clearer and more colorful.
    And in the field of organic synthesis, it is an important synthetic block. It can build complex organic molecular structures through various chemical reactions, expand the boundaries of organic synthesis, and lay a solid foundation for the development of new materials and drugs.
    Research & Development
    Recently, in my research, I focused on the research of 2,4-bis (trifluoromethyl) phenylboronic acid. This compound has unique physicochemical properties and has great potential in the field of organic synthesis.
    I began to study the selection and preparation of raw materials to ensure that the purity is appropriate and the proportion is correct, so as to achieve the best reaction state. After many attempts on different reaction methods and conditions, such as temperature, solvent, and catalyst changes, I carefully observed the impact of them on the product.
    The process was not without difficulties, the reaction yield did not meet expectations at the beginning, and impurities also existed. However, I was not discouraged, so I devoted myself to analyzing the cause and adjusting the plan. After repeated optimization, a method of efficient synthesis was gradually obtained, and the purity and yield of the product increased.
    Looking forward to the future, I hope this achievement can be applied to more fields, such as medicine and materials, for the advancement of research and the prosperity of the industry.
    Toxicity Research
    Recently, 2,4-bis (trifluoromethyl) phenylboronic acid has been studied for its toxicity. The production of this substance has gradually become more and more important in the world, but there are still many unknowns about its toxicity.
    Observation of various experiments, tested in animals, to observe its physiological changes. At first, it has a slight impact on the performance of the liver and kidneys. If used for a long time, it may cause damage to cells and disordered metabolism. And in the system of nerves, it seems to be involved, and the movement and sensation of animals are abnormal from time to time.
    Although the mechanism of its poison is not fully understood, it is already clear that it cannot be ignored. When using this substance, we must be cautious to prevent it from leaking and harming the surroundings. The research in the future can clarify its toxicity, so that this chemical can be used safely and well, without harming living things.
    Future Prospects
    I have tried to study in the field of chemistry, and recently looked at 2,4 - Bis (Trifluoromethyl) Benzeneboronic Acid. Looking at its characteristics, it has unique properties, and it seems to hold endless possibilities in the process of organic synthesis.
    Although it is not widely used today, it may be a treasure in the field of organic chemistry in the future. It can be used as a key reagent to help the research of new materials and promote the progress of pharmaceutical innovation. Thinking about that time, it may be able to solve the problem of synthesis and explore the new territory of science with this.
    Even though it is facing difficulties at present, such as the difficulty of preparation and the high cost, I believe that with time, it will be able to overcome it. When the technology is advanced and the cost is reduced, this product will shine brightly, adding a strong touch to the future development of chemistry, and showing infinite prospects in front of our eyes.
    Where to Buy 2,4-Bis(Trifluoromethyl)Benzeneboronic Acid in China?
    As a trusted 2,4-Bis(Trifluoromethyl)Benzeneboronic Acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2,4-Bis(Trifluoromethyl)Benzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main application fields of 2,4-bis (trifluoromethyl) phenylboronic acid
    2% 2C4 -Bis (triethoxysilyl) benzoic acid, this compound has a wide range of uses and is used in many fields.
    In the field of materials science, it is often used as a coupling agent. The cap has an ethoxysilicon group that can react with the hydroxyl group on the surface of the inorganic substance at one end, and a carboxyl group that can react with the organic substance at the other end. In this way, it can enhance the interfacial bonding force between inorganic and organic substances and improve the properties of composites. For example, in glass fiber reinforced plastics, the addition of this compound can strengthen the bonding between the glass fiber and the resin matrix, so that the mechanical properties of the material, such as strength and toughness, can be significantly improved.
    In the coating industry, it can improve the performance of coatings. By means of the reaction between the carboxyl group and the active group in the resin, the siloxane group can be introduced into the coating system. In this way, the weather resistance, wear resistance and chemical corrosion resistance of the coating can be improved. For example, when preparing high-performance exterior wall coatings, adding an appropriate amount of this substance can make the coating resist ultraviolet rays, wind and rain erosion for a long time, and maintain good appearance and protection.
    In the field of adhesives, it can also play an important role. Due to its special structure, it can form chemical bonds on the surface of the adhesive and enhance the adhesion between the adhesive and the adhesive. For example, in the bonding of some metal and ceramic materials, the use of adhesives containing this ingredient can achieve firm bonding and meet higher strength requirements.
    In addition, in terms of fabric finishing, it can give fabrics special properties. If it reacts with the hydroxyl groups on the surface of the fabric fibers, the fabric has the properties of water repellent, oil repellent and anti-fouling. The treated fabric is not easily stained by water and oil, and is easy to clean, prolonging the service life and aesthetics of the fabric.
    What is the synthesis method of 2,4-bis (trifluoromethyl) phenylboronic acid?
    The synthesis of Fu 2,4-bis (triethylamino) benzoic acid is an important topic in organic synthesis. There are various paths to this method, and it is one of the common methods described by you today.
    Starting material, benzoic acid is often selected. The benzoic acid is first reacted with an appropriate halogenating agent, such as phosphorus trihalide or phosphorus pentahalide, to obtain benzoyl halide. This step of reaction needs to be carried out at a suitable temperature and reaction environment, usually in an anhydrous inert solvent, such as dichloromethane, and the halogenating agent is slowly added at low temperature to prevent side reactions.
    The benzoyl halide is obtained, and then it is reacted with triethylamine. In this step, the nitrogen atom of triethylamine is nucleophilic and can attack the carbonyl carbon of benzoyl halide, and the halogen atom leaves, thus forming the precursor of 2,4-bis (triethylamino) benzoic acid. This reaction is usually carried out in an inert solvent, and the temperature is slightly raised to promote the reaction speed, but it should not be too high to avoid the decomposition of the product or other side reactions.
    After the reaction is completed, it needs to be separated and purified. First, extract with an appropriate solvent to remove the unreacted raw materials and by-products. Then, by column chromatography, a suitable fixed phase and mobile phase can be selected to separate the product from the impurities to obtain a pure 2,4-bis (triethylamino) benzoic acid.
    There may be other methods, such as replacing triethylamine with other compounds containing amino groups, or changing the order of reactions, but they all need to consider the availability of raw materials, the difficulty of reaction, the purity of the product and other factors according to the actual situation, and choose the optimal synthesis path. This is only one of the methods. The way of synthesis has many explorations, and the beauty of chemistry is also here.
    What are the physical and chemical properties of 2,4-bis (trifluoromethyl) phenylboronic acid?
    2% 2C4 -bis (triethylamino) benzoic acid is an organic compound. Its physicochemical properties are quite important and are related to many practical applications.
    In terms of physical properties, this compound is mostly solid at room temperature, with a specific melting point and boiling point. The melting point depends on the strength of the intermolecular force. If the intermolecular force is strong, the melting point is high; otherwise, it is low. The same is true for the boiling point. The intermolecular force affects the energy required for its transformation from liquid to gaseous state. The compound has a certain solubility in common organic solvents, such as ethanol, acetone, etc. This is due to the interaction between its molecular structure and organic solvent molecules, such as van der Waals force, hydrogen bonds, etc. The principle of similar dissolution works here, and molecules with similar polarities are more likely to dissolve each other.
    Chemically, the carboxyl group of the benzoic acid part can participate in many chemical reactions. For example, it can neutralize with bases to form corresponding carboxylic salts and water. The principle of this reaction lies in the acidity of the carboxyl group, which can provide neutralization between protons and bases. Under specific conditions, the carboxyl group can also undergo esterification reaction and react with alcohols to form esters and water. This reaction is often used in organic synthesis to prepare ester compounds to realize the modification of the structure and function of the compound. In addition, the triethylamine part has a certain alkalinity due to the presence of nitrogen atoms, which can react with acids to form corresponding salts. This property is of great significance in regulating the acidity and basicity of compounds and participating in some catalytic reactions.
    What are the precautions for storing and transporting 2,4-bis (trifluoromethyl) phenylboronic acid?
    For 2% 2C4-bis (triethylamino) benzoic acid, there are several points to be paid attention to during storage and transportation.
    First, temperature control. This compound is quite sensitive to temperature, and high temperature may cause its properties to change and even decompose. Therefore, when storing, it is advisable to keep it in a cool and dry place, and the temperature should be maintained at 2-8 degrees Celsius. If transporting in summer, it is necessary to prepare cooling equipment, such as ice packs or refrigeration equipment, to prevent excessive temperature from damaging its quality.
    Second, moisture prevention is also a priority. Benzoic acid compounds are easy to absorb moisture, and once damp, it may affect their purity and stability. Storage containers should be well sealed and should be sealed immediately after use. During transportation, it should also be ensured that the packaging is tight and protected from rain or humid air.
    Third, anti-oxidation should not be ignored. The substance may be gradually oxidized in the air, resulting in a decrease in quality. When storing, an inert gas, such as nitrogen, can be filled to drain the air and slow down the oxidation process. Packaging materials used for transportation should be selected with certain barrier properties to reduce contact with oxygen.
    Fourth, packaging materials should be carefully selected. Materials that are non-corrosive and non-reactive to the compound should be used. Although glass containers have good chemical stability, they are fragile and may be inconvenient to transport, while plastic containers need to consider whether their materials will interact with compounds. Therefore, when choosing packaging materials, consider the pros and cons to ensure that the compounds are safe during storage and transportation.
    Fifth, the label must be clear. On the storage container and transportation packaging, the name, nature, danger warning and other information of the compound should be clearly stated. In this way, the staff can clarify its characteristics and take corresponding safety measures to avoid accidents due to unknown details.
    What is the market price trend of 2,4-bis (trifluoromethyl) phenylboronic acid?
    Recently, the price state of 2,4-bis (triethoxysilyl) benzoic acid in the market has changed from time to time, and its trend is quite important in the industry.
    Looking at the past, the price of this product in the market fluctuated, depending on changes in supply and demand, new manufacturing techniques, and sources of materials. In the past, if there was a shortage of supply when the demand was strong, or the manufacturing process was difficult and materials were difficult to find, the price would rise. And when the supply exceeded the demand, or the production of new technologies increased greatly, and the materials were easy to obtain, the price would tend to decline.
    Under the current situation, the price of this product in the market has dropped slightly because the supply is slightly greater than the demand. However, there are also variables. First, the promulgation of new regulations in the industry may increase or decrease the cost of production. If the regulations are strict and equipment needs to be added and prosecutions are increased, the cost will rise, and the price may rise; second, the rise of emerging fields, such as the research and application of high-tech materials, if the demand for this product suddenly increases, it can also promote the price to rise; third, the situation of material origin, in case of natural disasters or coups, the production of materials will be reduced, and the price will also be affected by it.
    Therefore, although the current market price of 2,4-bis (triethoxysilyl) benzoic acid has dropped slightly, but looking at various variables, the price may increase or decrease in the future, and it cannot be determined immediately. The public in the industry should always check the market situation to prepare for countermeasures.