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2,4-Bis(Trifluoromethyl)Benzeneacetonitrile

2,4-Bis(Trifluoromethyl)Benzeneacetonitrile

Hongda Chemical

    Specifications

    HS Code

    921276

    Chemical Formula C10H5F6N
    Molecular Weight 253.14
    Appearance Solid (usually)
    Boiling Point Data may vary, check literature
    Melting Point Data may vary, check literature
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some organic solvents
    Density Data may vary, check literature
    Vapor Pressure Data may vary, check literature
    Flash Point Data may vary, check literature

    As an accredited 2,4-Bis(Trifluoromethyl)Benzeneacetonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 2,4 - bis(trifluoromethyl)benzeneacetonitrile in a sealed chemical - grade bottle.
    Storage 2,4 - bis(trifluoromethyl)benzeneacetonitrile should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents, acids, and bases as it may react with them. Suitable storage conditions help maintain its stability and safety.
    Shipping 2,4 - bis(trifluoromethyl)benzeneacetonitrile is shipped in specialized, tightly - sealed containers compliant with chemical transport regulations. Shipment is carefully monitored to ensure stability and prevent any risk of leakage during transit.
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    2,4-Bis(Trifluoromethyl)Benzeneacetonitrile 2,4-Bis(Trifluoromethyl)Benzeneacetonitrile
    General Information
    Historical Development
    History of 2,4-Bis (trifluoromethyl) phenylacetonitrile
    Taste the art of chemistry, the categories are rich, and the new substances are emerging in an endless stream. 2,4-Bis (trifluoromethyl) phenylacetonitrile, among chemical substances, also has its unique position.
    At the beginning, chemical scholars studied and explored, striving to clarify the properties of various substances and the method of preparing them. In the field of organic synthesis, people worked tirelessly to obtain new substances. This 2,4-bis (trifluoromethyl) phenylacetonitrile has gradually entered the field of vision with the evolution of organic synthesis technology.
    In the past, the synthesis method was still simple and difficult, and the yield was not abundant. However, the determination of scholars is determined, and they have repeatedly tried and innovated the method of synthesis. As a result, the technique of its preparation has been perfected day by day, and the yield has gradually increased. At present, this substance has applications in many fields such as medicine and materials. It really depends on the research of various sages in the past, which has made it unknown to the world and added a wonderful stroke to the history of chemistry.
    Product Overview
    Product Overview of 2,4-Bis (trifluoromethyl) phenylacetonitrile
    2,4-Bis (trifluoromethyl) phenylacetonitrile is a key compound in the field of organic synthesis. It has a unique structure and is composed of two trifluoromethyl and acetonitrile groups.
    This compound has a wide range of uses in pharmaceutical chemistry and is often an important intermediate for the synthesis of specific drugs. Because it contains trifluoromethyl, it can significantly change the physical and chemical properties of compounds and improve the lipid solubility and bioavailability of drugs. In the field of materials science, it may be a starting material for the creation of novel functional materials, endowing materials with special electrical, optical or thermal properties.
    Synthesis method, Chang Wright's specific organic reaction path requires precise control of reaction conditions, such as temperature, catalyst and reactant ratio, in order to achieve ideal yield and purity. The research and application of 2,4-bis (trifluoromethyl) phenylacetonitrile is opening up new possibilities for the chemical field and promoting related industries to a higher level.
    Physical & Chemical Properties
    2,4-Bis (trifluoromethyl) phenylacetonitrile, the physical and chemical properties of this substance are quite important. Its appearance is often colorless to light yellow liquid, with a specific odor. Physical parameters such as boiling point and melting point are the key to the study. The boiling point is related to its gasification conditions, and the melting point determines its phase transition. In terms of chemical properties, its molecular structure contains trifluoromethyl and cyano groups, resulting in its unique reactivity. The strong electron absorption of trifluoromethyl affects the charge distribution of molecules, making it easier for cyanos to participate in reactions, such as nucleophilic substitution. This compound has a wide range of uses in the field of organic synthesis and can be used as a key intermediate to help create a variety of functional organic materials and drugs. The study of its physical and chemical properties is of great significance for expanding its application.
    Technical Specifications & Labeling
    There is now a product named 2,4-bis (trifluoromethyl) phenylacetonitrile. Its process specification and identification (product parameters) are the key.
    The process specification needs to specify the preparation method, from the selection of raw materials, must be pure and sophisticated, to the control of reaction conditions, such as temperature, pressure, catalyst dosage, must be accurate and correct, so that the reaction can proceed efficiently and steadily according to the predetermined path. The reaction process should also be clear, the steps are closely connected, and there are no omissions. The
    label (product parameters) should clarify the properties of this product, whether it is solid or liquid, and what is the color and smell; give the purity value accurately, and the impurity content must be clear; as for the physical and chemical properties, such as melting point, boiling point, solubility, etc., should be carefully marked so that users can make good use of it according to its characteristics without error. In this way, it can be used in production and application to ensure the quality of this product and play its due effect.
    Preparation Method
    If you want to make 2,4-bis (trifluoromethyl) phenylacetonitrile now, you should study the method of preparation in detail. The selection of raw materials is related to the quality of the product. An aromatic halide and a cyanide-containing reagent can be used as the starting material, and the reactivity of the two is moderate, which can form the basic structure.
    Synthesis process, first mix the aromatic halide and an appropriate amount of catalyst in the reactor, control the temperature moderately, and slowly add the cyanide-containing reagent. In the meantime, stirring must be uniform to make the reaction sufficient. Temperature control is crucial. If it is too high, the side will be anti-clustered, and if it is too low, the reaction will be slow.
    Reaction step, the first is nucleophilic substitution, and the halogen Then, after the post-treatment process, the impurities are removed and purified to obtain a pure product.
    As for the catalytic mechanism, the catalyst used can reduce the reaction energy barrier and promote the reaction to proceed efficiently. Its activity check point interacts with the reactants, and the conductive sub-cloud rearranges, making the reaction easy. After these steps, high-quality 2,4-bis (trifluoromethyl) phenylacetonitrile may be obtained.
    Chemical Reactions & Modifications
    There is now a substance, called 2,4-bis (trifluoromethyl) phenylacetonitrile, which is very important in the field of chemistry, related to its chemical reaction and modification.
    Looking at the reaction of this substance, it can be combined with various reagents, and different changes can occur. Or in contact with nucleophiles, such as alkali, react at the carbon-nitrogen triple bond, making its structure easier to form new compounds.
    As for modification, the method of introducing groups can be used. If a group containing special functions is added, its physical and chemical properties may be changed. If a hydroxyl group is added, its hydrophilicity can be increased; if an aromatic group is added, its solubility and stability may be changed.
    The chemical changes and modifications of these substances are of great benefit to the process of organic synthesis, and can be the basis for the preparation of new materials and drugs. We need to explore them in depth to understand more mysteries.
    Synonyms & Product Names
    Today there is a product called 2,4-bis (trifluoromethyl) phenylacetonitrile. This product is quite important in the field of chemical research in our country. Its aliases are also common, and they all have different names due to different uses, production methods, and properties.
    In the chemical industry, people have different names. This 2,4-bis (trifluoromethyl) phenylacetonitrile, or due to the different synthesis paths, has a different name in the mouth of a certain school of craftsmen, just like the same school of learning, each has its own experience, and the name is also different.
    And because of its wide application, in different industries, the name of the product is also varied. Or it can be used in the production of fine chemicals, flavors, and pigments, and the craftsman then uses its effectiveness to choose a practical trade name; or it can be invested in pharmaceutical research and development to help synthesize good medicines, and the doctor also uses the name that is conducive to medical treatment according to its characteristics. These are all the wonders of synonyms and trade names, each according to its type and according to its needs.
    Safety & Operational Standards
    Specifications for the safety and operation of 2,4-bis (trifluoromethyl) phenylacetonitrile
    Fu 2,4-bis (trifluoromethyl) phenylacetonitrile is an important compound in chemical research. If you want to use it properly, you must clarify its safety and operation specifications in order to be safe.
    In terms of safety, this compound has certain chemical activity and potential harm. Its physical properties are special, and direct contact with skin and eyes must be avoided. If you accidentally touch it, rinse it with plenty of water as soon as possible. If the symptoms do not abate, seek medical attention. And its stability in the air should also be paid attention to, and it should be avoided in high temperature and open flames to prevent the risk of explosion.
    In terms of operating specifications, before the experiment, all utensils should be clean and dry to ensure the accuracy of the experiment. When weighing, use a precise weighing instrument to take the amount required by the experiment, not more or less. When dissolving this compound, choose the appropriate solvent, pour it slowly according to the proportion, and stir it lightly with a glass rod to promote its instant dissolution.
    During the reaction process, temperature, time, pH and other conditions must be strictly controlled. Set up a precise temperature control device and adjust it to a suitable temperature according to the reaction mechanism. Use a timer to measure the reaction time to prevent excessive or insufficient reaction. Use an acid-base indicator or pH meter to monitor the pH and adjust it in a timely manner.
    After the reaction is completed, the separation and purification of the product is also crucial. According to the characteristics of the product, choose distillation, extraction, recrystallization and other methods. During distillation, control the temperature and pressure; during extraction, choose the appropriate extractant; during recrystallization, choose the appropriate solvent and temperature.
    Finally, the safety and operation specifications for 2,4-bis (trifluoromethyl) phenylacetonitrile must be followed carefully, so that it can be used in chemical research without error, to ensure the safety of the experimenter, and to promote the smooth research.
    Application Area
    Today there is a product called 2,4-bis (trifluoromethyl) phenylacetonitrile. The application field of this compound is quite critical. In the process of pharmaceutical research and development, it can be an important raw material for the synthesis of active ingredients, and it can help medical scientists create new agents to treat various diseases. In the field of pesticides, it is also widely used, or it can be used to prepare high-efficiency and low-toxicity pesticides to protect crops from pests and ensure a good harvest. In the field of materials science, it can participate in the synthesis of special materials, making the materials specific and suitable for multiple scenarios. From this point of view, 2,4-bis (trifluoromethyl) phenylacetonitrile has considerable potential in the application fields of medicine, pesticides and materials, and is an important substance for scientific research and industrial development.
    Research & Development
    The industry of chemical industry is related to people's livelihood. With each passing day, new products emerge one after another. Today, there is a product called 2,4-Bis (Trifluoromethyl) Benzeneacetonitrile, which is unique in nature and has a wide range of uses. It has attracted the attention of many researchers.
    Our generation has dedicated themselves to studying, exploring the method of its synthesis, and seeking the best way. After repeated trials and repeated attempts to change, we can get something. When synthesizing, the ratio of raw materials, reaction temperature, and duration are all key. If there is a slight difference, it will be a thousand miles away.
    As for the expansion of applications, it is also difficult to think about. In the field of medicine, it is expected to become a new agent to treat human diseases; in terms of materials, it may be able to create strange materials to meet the needs of industry. However, the road ahead is long and full of difficulties. We should make unremitting efforts to promote the development of this product, contribute to the prosperity of the chemical industry, and live up to the original intention of research.
    Toxicity Research
    Study on the toxicity of 2,4-bis (trifluoromethyl) phenylacetonitrile
    There is currently a chemical substance called 2,4-bis (trifluoromethyl) phenylacetonitrile. For chemical researchers, the study of its toxicity is crucial.
    Looking at this substance, its molecular conformation contains special groups, or it is unique in toxicity. However, it has been observed that the clear analysis of its toxicity is still lacking. Although previous people have discussed this kind of structural compound, the details of this substance are not detailed.
    In experimental research, observe its effect on organisms. Take various organisms as a test to observe the changes in their physiological state and biochemical standards. If it enters the body, it may invade the structure and function of the cell, hindering the process of metabolism. And it is in the environment, or accumulated in the biological chain, causing ecological chaos.
    Our researchers should deeply explore the mechanism of its toxicity, seek protection strategies and treatment methods. Anticipate its nature, avoid harm and seek benefits, and do our best for the advancement of chemistry and the safety of human beings.
    Future Prospects
    The future development concerns 2,4-bis (trifluoromethyl) phenylacetonitrile, which is really the focus of our generation of chemical researchers. This material is unique and has the structure of trifluoromethyl. It has infinite possibilities in organic synthesis, medical research and other fields.
    Looking at the present, although research has made progress, the road ahead is still far away. Its synthesis method still needs to be refined, and it strives for high efficiency, green, and cost reduction and production. In medical research, it is hoped that it can tap its potential in the creation of new drugs and add new paths for the treatment of diseases and diseases. Material research and development may also be strange, or it can endow materials with special properties, such as corrosion resistance and photoelectric differences.
    We should have great ambitions and use scientific methods to explore the unknown. In time, this substance will bloom, create new trends in various fields, and become a strong foundation for future development. Benefit all people and recognize the power of science.
    Where to Buy 2,4-Bis(Trifluoromethyl)Benzeneacetonitrile in China?
    As a trusted 2,4-Bis(Trifluoromethyl)Benzeneacetonitrile manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2,4-Bis(Trifluoromethyl)Benzeneacetonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,4-bis (trifluoromethyl) phenylacetonitrile?
    2% 2C4 -bis (triethylamino) phenethyl ether is an important raw material commonly used in organic synthesis. It has a wide range of uses and plays a key role in many fields.
    First, in the field of pharmaceutical chemistry, this compound is often a key intermediate in drug synthesis. Due to its specific chemical structure, it can cleverly react with other compounds to build complex molecular structures with biological activity. Taking the development of some new antibacterial drugs as an example, 2% 2C4 -bis (triethylamino) phenethyl ether can provide a key support for the synthesis of core structures, helping drugs to achieve efficient inhibition and killing of specific bacteria, and contributing to pharmaceutical innovation.
    Second, in the field of materials science, its use should not be underestimated. Can participate in the preparation of functional polymer materials. When preparing high molecules with special electrical and optical properties, 2% 2C4 -bis (triethylamino) phenethyl ether is introduced into the main chain or side chain of the polymer, which can endow the material with unique properties. For example, when preparing photoelectric conversion materials, its special structure helps to improve the material's ability to absorb light and charge transport, improve the photoelectric conversion efficiency, and lay the foundation for the development of new optoelectronic devices.
    Furthermore, in the field of organic synthetic chemistry, as an important reaction substrate, it can participate in a variety of organic reactions, such as nucleophilic substitution reactions, coupling reactions, etc. Through these reactions, chemists can construct diverse organic compound structures, enrich the types of organic compounds, and provide more possibilities for the development of organic synthetic chemistry. In the synthesis of fine chemical products, it also plays an important role, assisting in the synthesis of fine chemicals such as special fragrances and dyes, and improving product quality and performance.
    What are the physical properties of 2,4-bis (trifluoromethyl) phenylacetonitrile?
    2% 2C4-Bis (triethoxypropyl) silicate is a class of organosilicon compounds. Its physical properties are unique, let me tell them one by one.
    Looking at its properties, it is usually a colorless and transparent liquid under normal circumstances. It is so clear that it is like a mountain spring, pure and impure. It has high transparency and good visibility. Under light, it shines brightly and reflects fascinating light and shadow.
    Talking about the boiling point, this substance has a high boiling point. Due to the force between molecules, it needs to supply a lot of energy to convert it from liquid to gas. This high boiling point property makes it stable in a high temperature environment, and it is not easy to evaporate and dissipate, just like a calm Gauge, unmoved by the external high temperature.
    Furthermore, its density is moderate, neither frivolous nor heavy as lead. Moderate density makes it able to skillfully integrate with other substances in various systems to find the right balance, just like long sleeves and harmonious coexistence in complex interpersonal situations.
    In terms of solubility, 2% 2C4-bis (triethoxypropyl) silicate is soluble in many organic solvents, such as ethanol and acetone. This solubility, like an elegant person with a wide range of friends, can be accepted and integrated with a variety of organic solvents, opening the door for its application in the chemical industry, and can be used in various reactions and preparations.
    Surface tension is also one of its important physical properties. Its surface tension is low, like a light boat on the water surface, easy to spread on the surface of the object, can be evenly covered, forming a dense film, laying a solid foundation for the application of material surface protection and modification, just like a skilled craftsman, carefully crafted every surface.
    In addition, the viscosity of 2% 2C4 -bis (triethoxypropyl) silicate is also characterized. The appropriate viscosity allows it to have a certain degree of fluidity, allowing it to operate smoothly during processing, while maintaining a certain shape, without being too scattered. It is like the ink in the pen of a calligraphy master, with a suitable thickness and freedom.
    What are the synthesis methods of 2,4-bis (trifluoromethyl) phenylacetonitrile?
    To prepare 2,4-bis (triethylamino) phenylacetamide, the method is as follows:
    First take an appropriate amount of phenylacetonitrile as the starting material and dissolve it in a suitable organic solvent, such as anhydrous ether or tetrahydrofuran. This is because it has good solubility and stable properties to the reactants, so as not to interfere with the reaction process.
    Then, slowly add triethylamine to it. When adding, pay attention to control the reaction temperature, which can generally be maintained in a low temperature environment, such as between 0-5 ° C. This is because the reaction is an exothermic reaction, and low temperature helps the reaction to proceed smoothly and avoid side reactions caused by excessive temperature. Triethylamine is used as a nucleophilic reagent in this reaction to attack the cyanocarbon of phenylacetonitrile and form a key intermediate product.
    After the first step of the reaction is completed and the intermediate product is stabilized, an appropriate acylating reagent, such as acetyl chloride or acetic anhydride, is added to the reaction system. This step also requires fine control of the reaction conditions, and the temperature can be gradually increased to near room temperature, about 20-25 ° C. The acylating reagent and the intermediate product undergo an acylation reaction, and finally the target product 2,4-bis (triethylamino) phenylacetamide is formed.
    After the reaction is completed, in order to obtain a pure product, a post-processing operation is required. The reaction mixture can be washed in a dilute acid solution to remove unreacted triethylamine and other basic impurities. After that, the product is extracted in an organic solvent, the organic phase is collected, and dried with anhydrous sodium sulfate to remove the moisture. Finally, the product is purified by reduced pressure distillation or column chromatography to obtain high-purity 2,4-bis (triethylamino) phenylacetamide.
    Another method is to use phenethylamine as the starting material. The phenethylamine is first reacted with appropriate protective reagents to protect the amino group from unnecessary side reactions in subsequent reactions. Commonly used protective groups such as tert-butoxycarbonyl (Boc), etc. After the protection is completed, the phenylacetamide derivative is reacted with triethylamine under specific conditions. The subsequent steps are similar to the method using phenylacetonitrile as the raw material. After acylation, deprotection and post-treatment, 2,4-bis (triethylamino) phenylacetamide can also be prepared. These two methods have their own advantages and disadvantages, and it is necessary to choose the appropriate one according to the actual situation, such as the availability of raw materials, the ease of control of reaction conditions and other factors.
    What are the precautions for storing and transporting 2,4-bis (trifluoromethyl) phenylacetonitrile?
    When storing and transporting 2% 2C4-bis (triethylamino) phenethyl ether, many things need to be paid attention to. This compound is a commonly used raw material for organic synthesis, and its properties may be more active. Therefore, environmental factors are the most important when storing. A cool, dry and well-ventilated place should be selected, away from fire and heat sources. It can easily cause combustion or even explosion due to high temperature or open flame, endangering safety.
    Furthermore, the tightness of the storage container must be preserved. If this compound is in contact with air for a long time, it may deteriorate due to oxidation and other reactions, which will affect the quality and utility. Containers should be made of corrosion-resistant materials to avoid chemical reactions between compounds and containers, damage to containers and leakage.
    When transporting, caution is also required. Suitable transportation tools and packaging methods should be selected according to their hazardous characteristics. Transportation vehicles must be equipped with fire and explosion-proof devices, and the route should avoid crowded areas and important facilities. During transportation, always pay attention to changes in temperature and humidity to prevent changes in the properties of compounds due to environmental factors.
    In addition, relevant operators must be professionally trained to be familiar with the characteristics and safe operation practices of this compound. Whether it is storage or transportation, corresponding emergency treatment equipment and protective equipment should be prepared. In case of emergencies such as leaks, they can respond quickly and properly to reduce hazards. Only by strictly adhering to the above precautions can the safety and stability of 2% 2C4-bis (triethylamino) phenethyl ether be ensured during storage and transportation.
    What are the effects of 2,4-bis (trifluoromethyl) phenylacetonitrile on the environment and human health?
    2% 2C4 -Bis (triethylamino) adipic acid, which has a significant impact on the environment and human health.
    At the environmental level, if this substance is accidentally released into nature, it may cause harm to ecosystems such as water bodies and soils. It may affect the survival and reproduction of aquatic organisms in water bodies. Aquatic organisms are extremely sensitive to chemical substances, which may interfere with their physiological functions, such as destroying their respiratory and reproductive systems. And it may accumulate in aquatic organisms and pass along the food chain, causing higher organisms to be implicated. In soil, or change the physical and chemical properties of soil, affect the structure and function of soil microbial communities, and then affect plant growth.
    As for human health, exposure to this substance poses many risks. If exposed to skin, it may cause skin allergies, redness, swelling, itching and other symptoms. Because it may irritate skin cells, it triggers an immune response. If inhaled inadvertently, or irritates the respiratory tract, causing cough, asthma, or even more serious respiratory diseases. Long-term exposure to this substance environment may damage the nervous system and endocrine system of the human body. The nervous system is affected, or it may cause symptoms such as headache, dizziness, insomnia, etc.; the endocrine system is damaged, or the hormone balance is disturbed, affecting the normal development and physiological functions of the body. Therefore, 2% 2C4-bis (triethylamino) adipic acid should be treated with caution, and proper protective measures should be taken during production and use to reduce its potential harm to the environment and human health.