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2,4,6-Trifluorobenzeneboronic Acid

2,4,6-Trifluorobenzeneboronic Acid

Hongda Chemical

Specifications

HS Code

494536

Chemical Formula C6H4BF3O2
Molecular Weight 175.90
Appearance White to off - white solid
Melting Point 153 - 157 °C
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
Pka Approximately 8 - 9 (boronic acid group)
Stability Stable under normal conditions, but sensitive to strong oxidizing agents

As an accredited 2,4,6-Trifluorobenzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 25g of 2,4,6 - trifluorobenzeneboronic Acid in sealed, labeled chemical - grade vial.
Storage 2,4,6 - trifluorobenzeneboronic acid should be stored in a cool, dry place away from heat and direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption and contact with air, which could lead to decomposition. Store it separately from incompatible substances, like strong oxidizing agents or bases, to avoid potential reactions.
Shipping 2,4,6 - trifluorobenzeneboronic acid is shipped in well - sealed containers, following strict chemical transportation regulations. Packaging ensures protection from moisture and damage during transit to maintain its quality.
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2,4,6-Trifluorobenzeneboronic Acid 2,4,6-Trifluorobenzeneboronic Acid
General Information
Historical Development
The historical development of 2,4,6-trifluorophenylboronic acid
I am committed to the research of 2,4,6-trifluorophenylboronic acid. The historical development of this compound is very interesting. At the beginning, the chemical technology was not refined, and the road to exploration was full of thorns.
In the past, chemists continued to study in the field of organic synthesis, hoping to find novel and practical reagents. People's attention gradually focused on fluorinated organoboron compounds, but the synthesis of 2,4,6-trifluorophenylboronic acid was not easy. Early attempts were frustrated due to harsh reaction conditions and low yield.
However, the scientific researchers were unyielding and improved the reaction process through repeated experiments. Or adjust the temperature and pressure, or change the catalyst and solvent. Finally, the reaction gradually stabilized and the yield improved.
To this day, 2,4,6-trifluorophenylboronic acid has emerged in the fields of medicine, materials, etc. Its historical development is the epitome of the progress of chemical scientific research, inspiring our generation to continue to forge ahead and explore the unknown.
Product Overview
2,4,6-Trifluorophenylboronic acid is also a key reagent in organic synthesis. It is a white to off-white crystalline powder with high chemical purity, and is mostly used in the fields of medicinal chemistry and materials science.
In drug research and development, with its unique chemical structure, it can participate in coupling reactions, help build complex molecular frameworks, and provide strong support for innovative drug creation. In the field of materials, functional groups can be introduced through specific reactions to optimize material properties, such as improving the photoelectric properties of materials.
Preparation of this product is often based on a specific chemical process and through multi-step reactions. During production, strict control of reaction conditions, such as temperature, reaction time and ratio of reactants, are all related to product purity and yield. And in storage and transportation, it is necessary to pay attention to moisture and heat protection to ensure its chemical stability. In this way, 2,4,6-trifluorophenylboronic acid can give full play to its effectiveness in various fields and promote the progress of science and technology.
Physical & Chemical Properties
Today, there is a substance called "2,4,6 - Trifluorobenzeneboronic Acid", whose physical and chemical properties are worth exploring. The color state of this substance, or a crystalline body, is clear in appearance, just like an ice crystal. What is its melting point? After careful measurement, it is about a specific temperature value, which is related to its morphological transformation in different environments.
As for chemical activity, it is unique because it contains fluorine, boron and other elements. Fluoride is very active and abnormal, so this substance often has different performances in chemical reactions. Boron is not idle, participating in many chemical processes, affecting its reaction path and rate. How is its solubility? It is soluble or insoluble in specific solvents, which is related to its application in various chemical operations. Detailed study of its physical and chemical properties can pave the way for applications in many fields.
Technical Specifications & Labeling
"On the Technical Specification and Labeling (Product Parameters) of 2,4,6-Trifluorophenylboronic Acid"
This product of 2,4,6-trifluorophenylboronic acid is described. Its technical specifications are related to the synthesis method and require precise steps. The choice of starting materials must be pure and fine, and the proportions must be unpleasant. The temperature of the reaction should be controlled in a suitable range, or a specific catalyst should be required to promote the smooth reaction.
As for the marking end, the product parameters should be detailed. Its purity geometry is the key to quality and should be shown by accurate data. Appearance properties should also be clear, either in a crystalline state or in a powder state. On the packaging, the characteristics of this product should also be clearly marked, such as the reaction of moisture and heat, to prevent the risk of storage and transportation. In this way, the essence of this product's technical specifications and labels can be obtained.
Preparation Method
The raw materials and production process are the key to the preparation of 2,4,6-trifluorophenylboronic acid. First take an appropriate amount of specific halogenated aromatics, which is the starting material. Using palladium compounds as catalysts, add organometallic reagents such as alkyl magnesium halides in a suitable reaction vessel, and prepare according to a specific ratio. Controlling the temperature in a precise range to make the two react is a key step. After the reaction is completed, the pure product is obtained by purification methods such as extraction, distillation, and removal of impurities. This preparation method requires strict control of the reaction conditions, close connection of each step, and catalyst activity also affects the yield and purity. In this way, 2,4,6-trifluorophenylboronic acid can be stably prepared.
Chemical Reactions & Modifications
Recently researched 2,4,6 - Trifluorobenzeneboronic Acid, this product, in the way of transformation, there are many thoughts and understandings.
In the past, all kinds of reactions were made, or the yield was not clear, and the side should be complicated. However, for the transformation of this product, I tried it with the usual method at the beginning, but the effect was not obvious. Thinking about the way of transformation, we need to observe the physical properties and study the mechanism, and seek new things in order to make changes.
Then change the conditions of response, adjust the temperature and change the agent, and hope that the transformation should take on a different appearance. Looking at it, the speed of response is slightly increased, but the disease of impure products still exists. Thinking about the change of activity, introduce other groups to adjust the cloth of its electron cloud, and hope that the activity will be adaptable. After several trials, the activity gradually became satisfactory, and the yield also increased.
Although it has not been perfected, progress has been made in the process of chemical adaptation and modification. In the future, we should continue to study it, hoping to obtain a wonderful method of chemical adaptation, so that the properties of this product can be perfect and used for all purposes.
Synonyms & Product Names
2,4,6-Trifluorophenylboronic acid, this substance is widely used in the field of chemical industry. Its synonyms and trade names are related to various channels of chemical industry.
Viewing ancient books, although they did not directly describe this substance, the way of chemical industry is in the same vein. Today's 2,4,6-trifluorophenylboronic acid, or in the way of organic synthesis, is a key agent. Its synonyms, or ordered by the ancestors in the industry, in recognition of its properties and uses. The name of the product, the merchant is in recognition of the excellence and quality of its products, and the name of special is also.
In the industry of organic synthesis, 2,4,6-trifluorophenylboronic acid is often an important corner of the reaction. Because of its fluorine-containing properties, it can make the reaction have different effects. Its synonyms and trade names are the key to communication in the industry. When peers hear its name, they will know its quality and its use, which is very beneficial for communication and cooperation. Therefore, exploring the synonyms and trade names of 2,4,6-trifluorophenylboronic acid is an important matter in chemical research, which is related to the prosperity of the industry and the progress of technology.
Safety & Operational Standards
2,4,6-Trifluorophenylboronic acid is also used in chemical products. If you want to obtain this product, you should follow the safe operation method to ensure safety.
All operations involving this product are the first to be safe. When handling it, you must take care to prevent it, such as gloves and eyes, to avoid the skin and eyes. Its chemical activity, or there is a risk of rot or irritation, and it is accidentally contaminated. If you quickly use a lot of water, you should ask for it.
Furthermore, the operation method is also essential. Store it in a good place where it is dry, dry and clear, and avoid fire sources and sources to prevent accidents. The solution of the solution should be mixed according to the proportion of precision, and it should be mixed with a certain degree. On the contrary, it is necessary to control the accuracy and accuracy, abide by the established process, and do not make mistakes.
In addition, things that are not suitable should not be removed, and they should be properly placed according to the situation. In this way, the safety of the operator can be guaranteed, and the profit of the reverse is also guaranteed. Safe operation is the way of chemical research.
Application Area
In the field of organic synthesis, 2,4,6-trifluorophenylboronic acid is also a chemical wonder. Its application field is quite wide. In the field of organic synthesis, it is often a key reagent, and can participate in many coupling reactions to make molecular structures ingenious, such as building complex aryl compounds to form exquisite structures. In the context of pharmaceutical research and development, it also has important functions. With its unique properties, it may be able to generate novel drugs and bring new opportunities for healing diseases. In the field of materials science, it can also help, or optimize material properties, such as improving the characteristics of photoelectric materials, so that materials can exhibit different properties. All of these highlight the potential of 2,4,6-trifluorophenylboronic acid in various fields, which cannot be ignored in chemical research and industrial practice.
Research & Development
Today, there is a product named 2,4,6-trifluorophenylboronic acid. As a chemical researcher, I have studied it for a long time. This material is unique and has a wide range of uses in the field of organic synthesis.
My preliminary investigation, scrutinized its structure in detail, analyzed its components, and understood the reasons for its characteristics. Then I studied the method of its preparation, and tried various paths to find an efficient and pure method. After several years, the best way was obtained, and the yield gradually increased, and the purity was also high.
In the face of application, observe its reaction with other substances, and explore its potential in the fields of medicine and materials. Looking at its results, there is great potential.
In the future, we hope to delve deeper and expand the boundaries of its application, so that this substance can bloom in the field of science, adding a weapon to our chemical researchers, promoting the progress of science and technology, and benefiting everyone.
Toxicity Research
Study on the toxicity of 2,4,6-trifluorophenylboronic acid
Fu 2,4,6-trifluorophenylboronic acid is a chemical research object. In the matter of toxicity research, it is quite important.
Now look at this substance, if you want to study toxicity, you should use a scientific method. First observe its contact with organisms, and observe whether it has damage to cells. Take white mice as a test, feed on food containing this substance, and observe its physiological changes.
If this substance enters the body, it may affect the function of organs. It is in the cell, or disrupts its structure, disrupts its metabolism. Observe the reaction, or has signs of inflammation, or causes functional decline.
Furthermore, consider its impact on the environment. If it flows in water and soil, it may harm life. Aquatic things may be poisoned by it, causing ecological turbulence.
Therefore, the toxicity study of 2,4,6-trifluorophenylboronic acid should not be ignored. When carefully investigated, its toxicity should be clarified to ensure the safety of life and the environment.
Future Prospects
Today there is a thing called 2,4,6 - Trifluorobenzeneboronic Acid, which is the object of chemical research. Looking at its properties, it has a unique structure and can play a wonderful role in the reaction.
Thinking about its future development, the future is bright. In the field of organic synthesis, it is expected to open up a new reaction path with its special structure, making the synthesis process more efficient and accurate. In the field of materials science, it may help to develop new materials with excellent performance, such as those with special optical and electrical properties, which can be applied to many cutting-edge technologies.
Furthermore, with the deepening of research, the understanding of its mechanism of action will become more thorough. At that time, we will be able to use this object more skillfully, contributing to the progress of chemistry and related fields, opening up infinite possibilities in the future, reaching unprecedented heights, and contributing to human well-being.
Where to Buy 2,4,6-Trifluorobenzeneboronic Acid in China?
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Frequently Asked Questions

As a leading 2,4,6-Trifluorobenzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,4,6-trifluorophenylboronic acid?
2%2C4%2C6-%E4%B8%89%E6%B0%9F%E8%8B%AF%E7%A1%BC%E9%85%B8%EF%BC%882%2C4%2C6-%E4%B8%89%E7%A2%B3%E5%9F%BA%E8%8B%AF%E7%A1%BC%E9%85%B8%EF%BC%89%E4%B8%BB%E8%A6%81%E7%94%A8%E9%80%94%E5%9C%A8%E5%8C%BB%E8%8D%AF%E3%80%81%E5%8C%96%E5%B7%A5%E3%80%81%E7%94%9F%E7%89%A9%E6%8A%80%E6%9C%AF%E7%AD%89%E9%9D%A2%E5%90%91%E3%80%82
** 5. Agroforestry **: In the field of agriculture and forestry, it can be used as a plant growth regulator, which helps to regulate the growth and development of plants, promote crop production, and improve the quality of agricultural products. For example, in the cultivation of some cash crops, rational use of it can make crops better absorb nutrients, enhance stress resistance, thereby improving yield and quality, and has a positive role in promoting the development of agroforestry.
What are the synthesis methods of 2,4,6-trifluorophenylboronic acid?
2%2C4%2C6-%E4%B8%89%E6%B0%9F%E8%8B%AF%E7%A1%BC%E9%85%B8%E5%90%88%E6%88%90%E6%96%B9%E6%B3%95%E5%B8%B8%E8%A7%81%E6%9C%89%E4%B8%8B%E5%88%97%E5%87%A0%E7%A7%8D%EF%BC%9A
1. Use phosphorus oxychloride and corresponding phenols as raw materials
Take an appropriate amount of phenol, such as 2,4,6-trimethylphenol, and place it in a clean reactor. Drain the air in the kettle with inert gas such as nitrogen to ensure that the reaction environment is oxygen-free. Slowly add phosphorus oxychloride dropwise, while closely monitoring the reaction temperature, generally maintaining an appropriate low temperature, such as 0-5 ° C. This process needs to be handled with caution, because phosphorus oxychloride is highly corrosive and reactive. After the dropwise addition is completed, gradually heat up to a suitable reaction temperature, such as 50-80 ° C, continue to stir, and react for several hours. After the reaction is completed, 2% 2C4% 2C6-trichlorobenzoic acid can be obtained through cooling, hydrolysis, purification and other steps. The hydrolysis step requires careful control of water volume and hydrolysis temperature to prevent excessive hydrolysis. The purification process can be recrystallized, column chromatography and other methods to obtain high-purity products.
2. Use halogenated aromatics as raw materials
Select suitable halogenated aromatics, such as 2,4,6-trichlorotoluene. Put it into the reaction vessel together with an appropriate amount of catalyst, such as cobalt salt, manganese salt, etc. Add an appropriate amount of solvent, such as glacial acetic acid, to help the reaction proceed evenly. Add an appropriate amount of oxygen to maintain a certain pressure, such as 1-3 MPa. Heat up to a suitable reaction temperature, about 100-150 ° C, and the reaction lasts for several hours. This oxidation reaction depends on the activity of the catalyst and the supply of oxygen, and needs to be monitored in real time. After the reaction is completed, the target product can be obtained through separation, refining and other operations. Filtration, distillation and other means can be used during separation, and crystallization and chromatographic separation can be further used for refining.
3. Take benzoic acid derivatives as raw materials
Take benzoic acid derivatives, such as 2,4,6-trimethoxybenzoic acid. Place it in a specific reaction system and add suitable halogenating reagents, such as chlorine gas, thionyl chloride, etc. The reaction conditions are controlled according to the characteristics of the halogenating reagents. If chlorine is used, it can be reacted in the presence of light or an initiator, and the reaction temperature depends on the situation, generally 50-100 ° C. If thionyl chloride is used, an appropriate amount of catalyst, such as DMF, is often added, and the reaction temperature can be controlled at room temperature to about 80 ° C. After the reaction is completed, after subsequent steps such as deprotecting the group, the final product is 2% 2C4% 2C6-trichlorobenzoic acid. The deprotecting step requires selecting an appropriate method according to the type of protecting group to ensure the integrity and purity of the product structure.
What are the physical and chemical properties of 2,4,6-trifluorophenylboronic acid?
2% 2C4% 2C6-tribromobenzoic acid, its physical and chemical properties can be investigated. This substance is in the form of white to light yellow crystalline powder at room temperature, and it looks fine and slightly shiny. Its melting point is quite high, about 200 degrees Celsius, which makes it stable in common environments as a solid state.
When it comes to solubility, it is slightly soluble in organic solvents, such as ethanol and ether. It is insoluble in contact with water. Because its molecular structure contains bromine atoms and benzene rings, it is highly hydrophobic, so it is difficult to melt in the polar environment of water.
Chemically, the carboxyl group of benzoic acid is acidic and can react with bases to neutralize and produce corresponding salts. And the bromine atom on the benzene ring makes it have a special performance in the electrophilic substitution reaction, which is more susceptible to the attack of electrophilic reagents than benzene. Because the bromine atom is an ortho-para-localization group, it can guide the reaction check point.
And because of its bromine content, it can be used as a bromine source in some specific reactions and participates in bromination and other reactions, giving it important use in the field of organic synthesis. This substance has potential value in many fields, such as medicine, pesticide synthesis, etc. The properties derived from its physical and chemical properties provide a wide range of related research and applications.
What are the precautions for storing and transporting 2,4,6-trifluorophenylboronic acid?
2%2C4%2C6-%E4%B8%89%E6%B0%9F%E8%8B%AF%E7%A1%BC%E9%85%B8, please pay attention to all the relevant matters.

The first heavy container. This acid is corrosive, so the container must be resistant to corrosion, such as glass, ceramics or specific plastic materials. Glass is not acidic, but it is fragile, and the anti-shattering measures are essential. Ceramics are also resistant to corrosion, but they are heavy and easy to wear. Plastic materials are easy to use and have good resistance. However, under high temperatures, there may be a risk of damage.
It should be placed in a safe, dry and clear environment. Avoid direct sunlight to prevent acid-causing properties. And it is necessary to avoid fire sources and oxidizing substances. This acid is not flammable. However, in case of oxidizing substances, or causing strong reactions, it will form a solid end.
The container needs to be properly fixed to prevent it from shaking and colliding. It is also necessary to clean it. It is also necessary to keep other chemical substances to prevent their acid from reacting. It is necessary for people who are poor to understand the nature of this acid. It is urgent.
Furthermore, it is clear that it is not clear. The hidden goods, or the tools used, are all dangerous, and the words "rotten goods" are used to make those who are poor aware of them, so that they should be careful.
In this way, 2%2C4%2C6-%E4%B8%89%E6%B0%9F%E8%8B%AF%E7%A1%BC%E9%85%B8 to the hidden environment, from the container, the environment, and the journey to the container, every problem cannot be ignored. In this way, the security is completely worried.
What is the market price of 2,4,6-trifluorophenylboronic acid?
I have heard your inquiry about the market price of 2,4,6-trifluorobenzoyl chloride. However, the price of the market is often uncertain due to changes in time, place, and supply and demand.
In today's world, there are many business routes, and the price of this product is related to many factors. The price of its raw materials, the difficulty of craftsmanship, the cost of manpower, and the difference in taxes can all cause its price to fluctuate. And the regions are different. The supply and demand situation varies from north to south to east, and the price is also different. If in the prosperous capital of Dayi, when demand is strong and supply is abundant, the price may stabilize; if in remote places, transportation is inconvenient, supply and demand are unbalanced, and prices may fluctuate.
Furthermore, the times change, and the market situation changes. In recent years, the rise and fall of the industry and the rise and fall of policies have also affected its price. The rise of new technologies may cause costs to fall and prices to fall; on the contrary, if raw materials are scarce and regulations become stricter, prices may rise.
To know the exact price, you should widely observe the market, consult merchants and brokers, and refer to recent transactions to make a more accurate judgment. It is not possible to judge based on old news and speculation alone. It is difficult to give you an exact price. I hope you can get clues by visiting the city in detail.