Hongda Chemical
Products
Home  /  Products  / 

2,4,6-Trifluorobenzeneacetonitrile

2,4,6-Trifluorobenzeneacetonitrile

Hongda Chemical

Specifications

HS Code

825916

Chemical Formula C8H4F3N
Molar Mass 171.12 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 196 - 198 °C
Density 1.325 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Flash Point 77 °C
Refractive Index 1.457 (20 °C)

As an accredited 2,4,6-Trifluorobenzeneacetonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram bottle packaging for 2,4,6 - trifluorobenzeneacetonitrile chemical.
Storage 2,4,6 - trifluorobenzeneacetonitrile should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent vapor leakage. It should be separated from incompatible substances like acids and bases. Label the storage container clearly to avoid misidentification.
Shipping 2,4,6 - trifluorobenzeneacetonitrile is shipped in well - sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring proper labeling and secure transportation to prevent spills and ensure safety.
Free Quote

Competitive 2,4,6-Trifluorobenzeneacetonitrile prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

2,4,6-Trifluorobenzeneacetonitrile 2,4,6-Trifluorobenzeneacetonitrile
General Information
Historical Development
Since 2024, the application of organofluorine compounds in various fields of chemical industry has become more and more extensive, and 2,4,6-trifluorobenzene acetonitrile has also emerged. Looking back in the past, the initial research on fluorinated organic compounds only involved the skin, and it was mostly limited by theoretical research, and little was done.
In recent years, chemical technology has become more and more exquisite, and breakthroughs have been made in the preparation process of 2,4,6-trifluorobenzene acetonitrile. In the past, the synthesis method was cumbersome, the yield was low, and the by-products were complicated. Today, new techniques have emerged, and the reaction conditions have been slowed down with an efficient catalytic system, and the yield has also increased significantly.
Its application scope has also gradually expanded. At first, it was only used in niche organic synthesis, and now it has been involved in key fields such as medicine and pesticides. In pharmaceutical research and development, with its unique chemical properties, it can make special new drugs; in pesticide creation, it can improve the efficacy and reduce environmental hazards. Looking at its development path, it has gradually flourished since the beginning, and the prospect should be more ambitious.
Product Overview
There is a substance today called 2,4,6 - Trifluorobenzeneacetonitrile. Its shape is also colorless to light yellow liquid, which is clear and translucent. Its properties are very active, and it is often used as a key raw material in many chemical reactions.
The structure of this substance is unique. On the benzene ring, fluorine atoms are three-dimensional side by side, and acetonitrile groups are connected on the side, giving it a different chemical activity. Because of the existence of fluorine atoms, the intermolecular forces are unique and the stability is also different.
In the field of synthesis, 2,4,6 - Trifluorobenzeneacetonitrile is widely used. It can be combined with a variety of reagents through a specific reaction path, and then many compounds with special properties can be derived. It can be used to create new types of drugs or to help synthesize high-end materials. It is an indispensable substance in chemical research and industrial production.
Physical & Chemical Properties
Today there is a thing called 2, 4, 6 - Trifluorobenzeneacetonitrile. The physical and chemical properties of this substance are relevant to our research. Its shape is either a colorless liquid or a crystalline state. Looking at its color, those who are pure should have no variegated color. If there are impurities, or slightly different colors. Its taste, or a special smell, this smell or pungent, or a different smell, all need to be carefully observed.
In terms of its boiling point, under a specific pressure, it can reach a certain temperature, which is the key to its gasification. The melting point is also an important sign, reflecting the temperature of its solid-state and liquid-state transition. Its solubility varies in different solvents. In polar solvents, it is soluble or slightly soluble; in non-polar solvents, it also has corresponding performance. This is the main point of exploring the physical and chemical properties of the substance, which is related to its wide application and research.
Technical Specifications & Labeling
Today there is a product called 2,4,6-trifluorobenzene acetonitrile. Its production method is related to technical specifications and identification (product parameters), which is the gist of our research.
To make this product, you need to know its materials first, and you need to use carefully selected raw materials, according to a certain ratio. In a clean device, the temperature is properly controlled, so that the materials can blend and react. During the period, the heat and time are fixed, and there is a slight difference, or the product is not good.
After it is made, check its quality. Looking at its color, it should be pure and free of impurities; observing its state, it should be in line with the established shape. More accurately, measure its purity, content and other parameters, and compare it with the preset standards. If all comply with the regulations, the logo can be affixed to show its quality and quantity, so that users can worry-free. This technical specification and logo (product parameters) are the key to ensuring the quality of 2,4,6-trifluorobenzene acetonitrile. We should carefully abide by it and make unremitting efforts.
Preparation Method
The preparation method of 2,4,6-trifluorobenzene acetonitrile is related to the raw materials and production process, reaction steps and catalytic mechanism.
To prepare this 2,4,6-trifluorobenzene acetonitrile, the first raw material is selected. Trifluorobenzene is used as the starting material, with cyanide reagent, these two are the key raw materials. As for the production process, the trifluorobenzene is first placed in a reaction kettle with a specific halogenating agent, heated at controlled temperature, halogenated, and halogenated to obtain halogenated trifluorobenzene. This step requires precise temperature control to ensure a smooth reaction.
Then, the halogenated trifluorobenzene and the cyanide reagent are mixed in a suitable solvent, and a catalyst is added to promote the This reaction step requires strict control of the reaction time and temperature to ensure the smooth introduction of cyanyl groups.
The catalytic mechanism cannot be ignored. The catalyst used can reduce the activation energy of the reaction and accelerate the reaction process. Select an efficient and selective catalyst to improve the purity and yield of the product.
After the above steps, following this preparation method, 2,4,6-trifluorobenzene acetonitrile can be obtained, which lays the foundation for subsequent chemical applications.
Chemical Reactions & Modifications
The way of chemical industry is related to the change of physical properties, and the reaction and modification are its cardinals. In this discussion of 2,4,6-Trifluorobenzeneacetonitrile, the chemical reaction and modification of this substance can be studied.
Looking at its reaction, or under specific temperature, pressure and catalytic conditions, its cyanyl group can interact with nucleophiles to generate new carbon-heterobonds, which is a commonly used method in organic synthesis. And the fluorine atom on the benzene ring has strong electron absorption, which affects the electron cloud density of the benzene ring, reduces the density of the adjacent and para-position electron clouds, and makes the site selection of the electrophilic substitution reaction different.
As for modification, different functional groups can be introduced to change its physical and chemical properties. Such as grafting long chain alkyl, or can increase its fat solubility; the introduction of polar groups containing nitrogen and oxygen, or can change its solubility and reactivity. In this way, it can be used to meet the needs of different industries and scientific research. This is the way to explore the reaction and modification of 2,4,6-Trifluorobenzeneacetonitrile in chemical research.
Synonyms & Product Names
Today there is a thing called 2,4,6 - Trifluorobenzeneacetonitrile. The synonyms of this thing and the name of the product need to be carefully examined.
The husband is a synonym, so it expresses its characteristics, and it has a different name and refers to the same. The name of the product is related to the easy circulation of the market, and the merchants use it to identify their products. In the field of chemistry, exploring these two is still a good way to find out its characteristics, uses and various relationships.
We are chemical researchers, and we should carefully study the synonyms of 2,4,6 - Trifluorobenzeneacetonitrile, either from its structural characteristics, or because of the naming habits of the past; as for the name of the product, or for the needs of the merchant to promote, it is easy to remember and can show the characteristics. Examining these two things in detail is beneficial to both chemical research and industrial applications, and can help us better grasp the full picture of this object, so as to promote the progress of chemistry and the development of industry.
Safety & Operational Standards
Specifications for safety and operation of 2,4,6-trifluorobenzene-acetonitrile
For chemical products, their properties are not special, so safe operation is of paramount importance.
#First, the essentials for storage
This product should be stored in a good place where it is dry, dry and well-connected. To avoid the source of fire and explosion. Do not mix oxidation, acid, and other substances to prevent the generation of chemical reactions. The room should be controlled in terms of temperature, and there is no relevant fire equipment leakage.
#Second, the operation of the
operation of the
operation, the
must wear appropriate anti-damage, such as anti-clothing, gloves, eyes, etc., to prevent skin damage, eye contact. The operation environment needs to be well connected to avoid evaporation and accumulation. Use this product, it is appropriate to prevent leakage. If you accidentally leak, immediately isolate the pollution and limit the entry and exit of people. A small amount of leakage can be absorbed by inert materials such as sand and vermiculite; if there is a large amount of leakage, it needs to be contained in the embankment or dig a pit, and covered with foam to reduce the damage of steaming.
#III.
2,4,6-trifluorobenzene acetonitrile, and comply with the phase method.
Therefore, it is necessary to ensure the safe operation of 2,4,6-trifluorobenzene acetonitrile, and to protect the safety and environment of people.
Application Area
In 2024, the application field of the chemical 2,4,6-trifluorobenzene acetonitrile will gradually become more and more important in the academic community.
In the field of pharmaceutical chemistry, it can be used as a key intermediate. If you want to make specific antiviral drugs, 2,4,6-trifluorobenzene acetonitrile participates in specific reactions. After delicate transformation, it adds a unique structure to the drug molecule, enhances the binding force with the virus target, and enhances the efficacy.
In materials science, it also has extraordinary performance. Using this as a raw material, through a series of synthesis processes, high-performance liquid crystal materials can be made. In the display device, this kind of material optimizes the display image quality by virtue of its unique molecular arrangement and optical properties, making the image clearer and more colorful.
Furthermore, in the development of pesticides, 2,4,6-trifluorobenzene acetonitrile can be derived from high-efficiency and low-toxicity insecticides. With its chemical properties, it precisely acts on the nervous system or metabolic pathway of pests to achieve good insecticidal effect, and has a slight impact on the environment and non-target organisms.
In summary, 2,4,6-trifluorobenzene acetonitrile has great potential in many fields. Over time, it will surely contribute to scientific and technological progress and social development.
Research & Development
In recent years, I have focused on the research of 2, 4, 6 - Trifluorobenzeneacetonitrile. This compound has a unique structure and great potential in the field of organic synthesis.
At the beginning, I explored its synthesis path, and many attempts were made, but after many ups and downs. The traditional method, the yield was not as expected, and there were many impurities. Then I devoted myself to research, improve the process, and try new catalysts and reaction conditions.
After repeated tests, a method was finally obtained, which can improve the yield and the purity of the product is quite high. At the same time, its stability and reactivity were considered, which paved the foundation for subsequent applications.
Looking to the future, we want to expand its application in medicine, materials and other fields. We hope to develop more novel and practical products based on this, promote the development of this field, and contribute to the industry. We hope to achieve our ambitions and live up to our research.
Toxicity Research
Today there is a thing called 2,4,6 - Trifluorobenzeneacetonitrile. I am a chemical researcher. Detecting its toxicity is a top priority.
The toxicity study of this thing is related to the safety of living beings and the tranquility of the environment. Only by probing its properties can we know the effect it has on living organisms. Or by observing its path into the body, through the mouth, through the skin or inhalation, all need to be carefully investigated. Looking at its metabolism in the body, the biochemical changes involved cannot be ignored.
Also examine its impact on the environment. The diffusion and transformation between water, soil and air are all related to ecological balance. If this thing is toxic, it may cause biological diseases and ecological problems if it is accidentally released. Therefore, it is necessary to study the toxicity of 2, 4, 6-Trifluorobenzeneacetonitrile in detail, so as to ensure the safety of all beings and the permanence of the environment.
Future Prospects
In today's world, the industry of chemistry is flourishing and flourishing. Among all kinds of chemical products, 2, 4, 6-Trifluorobenzeneacetonitrile this thing, which is quite eye-catching. Its unique nature and wide range of uses have been revealed, but the future prospects are still promising.
Today's research has begun to see its ability, and it has also been gained in the synthesis method. However, with the development of science and technology, we should seek better systems in the future, reduce its costs and increase its yield. And this thing has potential in various fields such as medicine and materials. In the future, new drugs may be developed to overcome difficult diseases; or new materials can be created to meet various needs.
We chemists should be enterprising and study unremitting. With time, we will be able to make 6-Trifluorobenzeneacetonitrile 2, 4, give full play to its ability to contribute to the well-being of mankind and achieve future brilliance.
Where to Buy 2,4,6-Trifluorobenzeneacetonitrile in China?
As a trusted 2,4,6-Trifluorobenzeneacetonitrile manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,4,6-Trifluorobenzeneacetonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,4,6-trifluorophenylacetonitrile?
2% 2C4% 2C6-tribromobenzoic acid, its main uses are as follows:
This substance is used in the field of medicine and can be used as a key intermediate. Due to its specific chemical structure and activity, it can participate in many drug synthesis reactions. Taking a new type of antibacterial drug as an example, 2% 2C4% 2C6-tribromobenzoic acid acts as an important starting material. After multiple steps of exquisite chemical reaction, it can construct a complex molecular structure with antibacterial activity, which adds to the human resistance to the invasion of pathogens.
In the field of materials science, it can be used to prepare special polymer materials. Because of its bromine atom, it endows the material with excellent flame retardancy. This substance is introduced in the synthesis of special engineering plastics. When the material encounters an ignition source, bromine atoms will undergo a series of reactions when heated, interfering with the combustion chain reaction process, slowing down the combustion rate, and greatly improving the fire safety of materials. It is of great significance in fields with strict fire protection requirements such as construction and electronic equipment.
In organic synthetic chemistry, it is an extremely important reagent. It can participate in the functionalization of aromatic compounds by virtue of its unique chemical properties. For example, under specific catalysts and reaction conditions, it undergoes a substitution reaction with other aromatic hydrocarbons to introduce specific functional groups into organic molecules, thereby expanding the structural diversity of organic compounds, laying the foundation for the research and development of new organic functional materials and drugs, and helping organic synthetic chemistry to continuously explore new fields.
What are the physical properties of 2,4,6-trifluorophenylacetonitrile?
2% 2C4% 2C6-tribromobenzoic acid, its physical properties are as follows:
This substance is mostly white to light yellow crystalline powder at room temperature, and its texture is fine. It has a certain stability, and under normal environmental conditions, it is not easy to undergo violent chemical changes on its own.
The melting point is within a specific range, about [X] ° C. This characteristic allows it to be converted from solid to liquid at a specific temperature, and a phase transition occurs. Its boiling point also has a corresponding value, which is [X] ° C. When the temperature rises to the boiling point, it will be converted from liquid to gas.
In terms of density, it is about [X] g/cm ³, which is moderately dense compared to some common organic compounds. In terms of solubility, it is slightly soluble in water, and it is difficult to disperse and dissolve in large quantities in water. This is due to its molecular structure and the force between water molecules. However, it is soluble in a variety of organic solvents, such as ethanol, ether, etc. In these organic solvents, a uniform dispersion system can be formed, showing good solubility.
In addition, the crystal structure of 2% 2C4% 2C6-tribromobenzoic acid is regular and orderly, giving it certain optical properties. Under light irradiation, it can exhibit specific optical phenomena such as luster and refractive index. And because of the connection of atoms in the molecule and the distribution of electron clouds, it has absorption characteristics for electromagnetic radiation of specific frequencies, which is reflected in the spectral characteristics such as infrared spectrum and ultraviolet spectrum. All these physical properties lay the foundation for in-depth understanding and application of this substance.
Is the chemical properties of 2,4,6-trifluorophenylacetonitrile stable?
The chemical properties of 2% 2C4% 2C6-tribromophenylacetamide are still stable. In this compound, the bromine atom is connected to the benzene ring and acetamide group, and the structure endows it with certain stability.
From the perspective of molecular structure, the benzene ring has a conjugated system, and the electron cloud is evenly distributed and delocalized. This characteristic makes the benzene ring part relatively stable, and it is not easy to occur general ring opening or violent reactions. In the acetamide group, the carbonyl group interacts with the amino group through the conjugation effect, which also makes the structure of this part relatively stable.
Furthermore, although the bromine atom has a certain electronegativity, after being connected to the benzene ring, its activity is regulated to a certain extent, and it is not easy to break away at will or cause violent reactions. Under common chemical reaction conditions, 2% 2C4% 2C6-tribromophenylacetamide can usually maintain its own structural integrity and exhibit good stability without specific reagents and conditions.
However, it should be noted that the stability is not absolute. Under extreme conditions of high temperature, strong acid and base, or the presence of specific catalysts, its structure may change. For example, in a strong acid environment, the acetamide group may hydrolyze; when there is a strong oxidizing agent at high temperature, the benzene ring or bromine atom may also participate in the reaction. However, under conventional environment and general experimental operating conditions, 2% 2C4% 2C6-tribromophenylacetamide can be regarded as a chemically stable substance.
What are the synthesis methods of 2,4,6-trifluorophenylacetonitrile?
The synthesis method of 2% 2C4% 2C6-trifluoromethylphenylacetic acid is related to the technology of organic synthesis, which is a very important research direction in the field of chemistry. The following are some common synthesis methods detailed by you:
First, halogenated aromatics are used as starting materials. First, halogenated aromatics interact with metallic magnesium to form Grignard reagents. Grignard reagents are highly active and can undergo nucleophilic substitution reactions with trifluoromethylhaloalkanes to introduce trifluoromethyl. Then, through carbon dioxide carboxylation, that is, reacting Grignard reagents with carbon dioxide gas at low temperatures, the corresponding trifluoromethylbenzoic acid can be prepared. Finally, benzoic acid is reduced to phenylacetic acid by a reduction reaction, such as the use of reducing agents such as lithium aluminum hydride, to obtain 2% 2C4% 2C6-trifluoromethylphenylacetic acid. Although there are many steps in this method, the reaction conditions of each step are relatively mild and the yield is relatively considerable.
Second, the Fu-gram reaction is used. Benzene and its derivatives are used as substrates. Under the catalysis of Lewis acid catalyst, such as anhydrous aluminum trichloride, the Fu-gram acylation reaction occurs with trifluoroacetyl chloride to generate trifluoromethylacetophenone. Then, through haloform reaction, such as reaction with sodium hypohalite, acetophenone can be converted into benzoic acid, and then phenylacetic acid can be obtained through the reduction step. This approach takes advantage of the characteristics of Foucault reaction to efficiently introduce acyl groups, but attention should be paid to the control of reaction conditions to prevent side reactions.
Third, the diazonium salt is used as the intermediate. First, the corresponding amine compound is converted into a diazonium salt through a diazotization reaction. The diazonium salt has poor stability and can decompose under specific conditions. Using this property, the diazonium salt is reacted with a trifluoromethylation reagent to achieve the introduction of trifluoromethyl. The subsequent steps of carboxylation and reduction complete the synthesis of 2% 2C4% 2C6-trifluoromethylphenylacetic acid. The key to this method lies in the precise operation of the diazotization reaction and the appropriate choice of subsequent reaction conditions.
The synthesis of 2% 2C4% 2C6-trifluoromethylphenylacetic acid has various methods, each with its own advantages and disadvantages. The best synthesis path should be carefully selected according to actual needs, considering the availability of raw materials, the difficulty of controlling reaction conditions, yield and purity requirements and many other factors.
What should be paid attention to when storing and transporting 2,4,6-trifluorophenylacetonitrile?
2%2C4%2C6-%E4%B8%89%E6%B0%9F%E8%8B%AF%E4%B9%99%E8%85%88%E5%9C%A8%E5%82%A8%E5%AD%98%E5%92%8C%E8%BF%90%E8%BE%93%E6%97%B6%E5%BF%85%E9%A1%BB%E6%B3%A8%E6%84%8F%E4%B8%8B%E5%88%97%E4%BA%8B%E9%A1%B9%EF%BC%9A
** First, about storage **:
This medicine should be placed in a cool and dry place, away from fire sources and hot topics. Due to high temperature, or the variation of the ingredients causing the medicine, the efficacy of the medicine will be damaged. If it is in a humid place, the medicine is prone to moisture and mildew, which will also damage the efficacy of the medicine. And it should be placed beyond the reach of children to prevent accidental ingestion and endanger life.
** Second, when transporting **:
The handling process must be handled with care. The internal structure of this medicine may change due to violent vibration, which will affect the quality. The means of transportation used must be clean and hygienic, without odor, otherwise the medicine will easily absorb odor and affect its original nature. In addition, the temperature and humidity during transportation also need to be strictly controlled, and transportation equipment with temperature and humidity control function should be used to maintain the stability of the medicine. If it is transported in high temperature season, special attention should be paid to cooling measures; if it is transported in humid areas, it is necessary to do a good job of moisture prevention. In this way, the quality of 2%2C4%2C6-%E4%B8%89%E6%B0%9F%E8%8B%AF%E4%B9%99%E8%85%88 during storage and transportation can be guaranteed, and the efficacy can be preserved.