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2,4,6-Trifluorobenzene-1-Sulfonyl Chloride

2,4,6-Trifluorobenzene-1-Sulfonyl Chloride

Hongda Chemical

    Specifications

    HS Code

    886617

    Chemical Formula C6H2ClF3O2S
    Molecular Weight 246.59
    Appearance Typically a colorless to light - yellow liquid
    Boiling Point Data may vary, but around [specific value if known] °C
    Melting Point Data may vary, but around [specific value if known] °C
    Density Data may vary, but around [specific value if known] g/cm³
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Reactivity Reactive towards nucleophiles, can participate in sulfonylation reactions
    Flash Point Data may vary, but around [specific value if known] °C
    Hazard Class Corrosive, may cause burns to skin and eyes

    As an accredited 2,4,6-Trifluorobenzene-1-Sulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 2,4,6 - trifluorobenzene - 1 - sulfonyl chloride in sealed chemical - grade packaging.
    Storage 2,4,6 - trifluorobenzene - 1 - sulfonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly sealed container to prevent moisture absorption and contact with air, as it may react. Store separately from incompatible substances like bases, reducing agents, and reactive metals to avoid hazardous reactions.
    Shipping 2,4,6 - trifluorobenzene - 1 - sulfonyl chloride is shipped in well - sealed, corrosion - resistant containers. Strict adherence to hazardous chemical shipping regulations ensures safe transportation, protecting both handlers and the environment.
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    2,4,6-Trifluorobenzene-1-Sulfonyl Chloride 2,4,6-Trifluorobenzene-1-Sulfonyl Chloride
    General Information
    Historical Development
    In the past, I have dedicated myself to the research of chemical substances, especially the product 2, 4, 6 - Trifluorobenzene - 1 - Sulfonyl Chloride. At the beginning, it was also to explore its properties and investigate its source, in order to understand its effect in various reactions. At the beginning, I studied the method of its synthesis, and after several trials, it was all accumulated.
    At that time, the chemical technology was not as sophisticated as it is today, and it was difficult to synthesize this product. The choice of raw materials and the control of conditions all need to be considered. However, I was not discouraged. I found the cause in failure and sought improvement in success.
    As the years passed, the technology was gradually perfected. The method of synthesis was simplified from complex to simple, and the yield also gradually increased. The nature of this product is also more clear, and it is gradually used in the fields of organic synthesis. Looking at its development process, it is like sailing against the current. If you don't advance, you will retreat. Only by persevering in research can you achieve results.
    Product Overview
    Today there is a substance called 2,4,6-trifluorobenzene-1-sulfonyl chloride. Its color is pure and pure, and it is crystal clear. This substance is strong and active in reactions, and is often a key material in organic synthesis.
    Looking at its structure, above the benzene ring, fluorine atoms and sulfonyl chloride groups are cleverly arranged. The introduction of fluorine atoms gives it a unique electronic effect, which makes the chemical properties of the compound unique. The sulfonyl chloride group is an active check point for its participation in many chemical reactions, and can be converted into various compounds.
    In the process of synthesis, 2,4,6-trifluorobenzene-1-sulfonyl chloride can combine with many reagents such as alcohols and amines to form various sulfonamides, sulfonate esters and other derivatives. These derivatives have extraordinary uses in the fields of medicine, pesticides, materials, etc., or as a good medicine for treating diseases, as a good agent for protecting crops, or as an auxiliary agent for material modification, which is a treasure in the chemical industry.
    Physical & Chemical Properties
    2,4,6-Trifluorobenzene-1-sulfonyl chloride is an important substance in chemical research. Its physical and chemical properties are particularly critical. Looking at its physical properties, at room temperature, this compound is mostly [specific physical state, such as solid state, describe appearance, etc.]. Its melting point is about [X] ° C, and its boiling point is about [X] ° C. Due to the characteristics of fluorine atoms in the molecular structure, it has certain volatility.
    In terms of its chemical properties, the activity of sulfonyl chloride groups is quite high. It is easy to react with nucleophiles. In case of alcohols, sulfonates can be formed; in case of amines, sulfonamides can be formed. Due to the electron-withdrawing effect of the fluorine atom on the benzene ring, the electron cloud density of the benzene ring decreases, which affects its aromaticity-related reactivity. This compound has a wide range of uses in the field of organic synthesis and can be used as a key intermediate to create a variety of fluorine-containing organic compounds. With its unique physical and chemical properties, it has potential application value in many fields such as materials science and medicinal chemistry.
    Technical Specifications & Labeling
    There is a substance today, called 2,4,6-trifluorobenzene-1-sulfonyl chloride. If you want to clarify its technical specifications and identification (product parameters), you should check it carefully.
    The technical specifications of this substance are related to purity and impurity content. The purity should be high, and the impurities must be controlled at an extremely low level. If the purity is not reached, or the subsequent reaction deviation will be caused, which will affect the quality of the product. Excessive impurities may also lead to side reactions, which will only increase costs and damage benefits.
    In terms of identification, its chemical name, molecular formula, molecular weight and other parameters should be stated. The chemical name is 2,4,6-trifluorobenzene-1-sulfonyl chloride, and the molecular formula and molecular weight are accurately marked, so that the user can see at a glance without the risk of misuse. In this way, it is necessary to ensure that this product can be properly applied in the fields of chemical research and production and exert its due effectiveness.
    Preparation Method
    The method of preparing 2,4,6-trifluorobenzene-1-sulfonyl chloride is related to the raw materials and production process, reaction steps and catalytic mechanism. The first thing to do is to prepare suitable raw materials, such as fluoroaromatic hydrocarbons and sulfonating reagents. In ancient theory, it is necessary to choose pure materials carefully, but impurities hinder the reaction.
    Its production process first makes fluoroaromatic hydrocarbons and sulfonating reagents meet under specific conditions. Or the temperature is controlled to a moderate extent, if it is overheated, it will cause side effects, and if it is too cold, the reaction will be delayed. The reaction step may be electrophilic substitution at the beginning, and the sulfonyl group gradually enters the position of aromatic hydrocarbons. Catalytic mechanism, or use a suitable catalyst, to promote the rapid progress of the If a certain metal salt is used as catalyst, the energy barrier of the reaction can be lowered, and the molecular activity can be changed to make the reaction go forward. In this way, 2,4,6-trifluorobenzene-1-sulfonyl chloride can be prepared according to this method.
    Chemical Reactions & Modifications
    The industry of chemical industry is related to the change of substances, and the beauty lies in the reaction and modification. Today, there are 2,4, 6-Trifluorobenzene-1-Sulfonyl Chloride. In the field of chemistry, its reaction and modification are worth exploring.
    Looking at its reaction, it encounters with various reagents, or causes nucleophilic substitution, or induces electron transfer changes. Its chlorosulfonyl group is active and easy to be replaced by other groups. If it encounters alcohols, it becomes a sulfonate. The mechanism is that nucleophilic reagents attack its power-deficient center.
    As for modification, according to its fluorine-containing properties, a specific structure can be introduced to increase the stability and hydrophobicity of the product. Fluorine has strong electronegativity, which can change the intermolecular force and then change its physical and chemical properties. For materials and medicine, it is expected to use this to make special agents.
    However, the reaction conditions are essential, and temperature, pressure, and catalysis can all affect its results. Precise control can lead to ideal products. In the process of chemical refinement, this is the key and cannot be ignored.
    Synonyms & Product Names
    Today there is a thing named "2,4,6 - Trifluorobenzene - 1 - Sulfonyl Chloride". Its synonymous name is also the focus of our investigation. Looking at this substance, in the field of chemical industry, it has a wide range of uses. Or it can be used as a raw material for organic synthesis to make various fine chemicals.
    As far as synonymous names are concerned, they are born due to differences in regions and industry habits. In Western countries, the name is established and spread all over the world. However, in the land of China, the translation of its name is also different. Or according to its chemical structure, explain in detail, so there are other names.
    In the industry, it is crucial to clarify its synonymous name and trade name. When purchasing, there is no risk of mistaken recognition; the communication between studies is also smooth. Although this product belongs to the chemical micro-end, the identification of its synonymous name and trade name is related to the development of the industry and the progress of academia. It must be carefully studied and cannot be ignored.
    Safety & Operational Standards
    Specifications for the safety and operation of 2,4,6-trifluorobenzene-1-sulfonyl chloride
    For 2,4,6-trifluorobenzene-1-sulfonyl chloride, it is also a reagent used in chemical production. It is active and has special chemical properties. Therefore, during operation and storage, it is necessary to strictly observe safety and operation specifications to avoid hazards.
    #1. Storage rules
    This product should be stored in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent changes in its reactivity caused by rising temperature and cause danger. The storage area should be prepared with suitable materials to contain leaks. And it should be stored separately from oxidants and alkalis, and should not be mixed. The reason is that 2,4,6-trifluorobenzene-1-sulfonyl chloride is easy to react in case of alkali, contact with oxidants or cause violent reactions, endangering safety.
    #2. The essentials of operation
    When operating, be sure to ensure good ventilation, preferably in a fume hood. Operators should be professionally trained, familiar with operating procedures, and operate strictly in accordance with regulations. Appropriate protective clothing, gloves and protective glasses are required to prevent the product from contacting the skin and eyes. Because it is corrosive, once exposed, it can cause burns.
    When taking 2,4,6-trifluorobenzene-1-sulfonyl chloride, the action should be slow to avoid spillage. If there is a spillage, emergency measures should be taken immediately. A small amount of spillage can be mixed with sand, dry lime or soda ash and collected in a closed container; if there is a large amount of spillage, it is necessary to build a dike or dig a pit for containment, and transfer it to a tanker or a special collector for recycling or transportation to a waste treatment site for disposal.
    During the reaction process, the reaction conditions, such as temperature, pressure, and the proportion of reactants, should be precisely controlled. Due to its high reactivity, the conditions are slightly deviated, or the reaction may be out of control. After the reaction is completed, the remaining 2,4,6-trifluorobenzene-1-sulfonyl chloride should also be properly disposed of according to regulations and should not be dumped at will.
    All these safety and operating standards are to ensure the safety of personnel and the smooth production. Operators must not ignore this.
    Application Area
    Today there is a product called 2,4,6 - Trifluorobenzene - 1 - Sulfonyl Chloride. The application field of this product is quite wide. In the field of medicinal chemistry, it can be a key intermediate to help create new drugs to cure various diseases and eliminate diseases for the common people. In material science, it can also play a wonderful role, or it can improve the properties of materials to make them more resilient and stable, so that they can be applied to various special scenarios. And in the field of organic synthesis, with its unique chemical properties, it can participate in many delicate reactions, build complex organic molecular structures, expand the boundaries of organic synthesis, contribute to the progress of chemical research, lead the exploration of unknown areas, open a new chapter, and show extraordinary potential and value in various application fields.
    Research & Development
    There is a chemical substance known as 2,4,6-trifluorobenzene-1-sulfonyl chloride. As a chemical researcher, I am very concerned about the research and development of this substance.
    This compound has unique properties, and the presence of fluorine atoms in its structure endows it with special chemical activities and physical properties. I initially studied this compound to investigate its reaction mechanism in detail and to explore various reagents that can react with it. After many experiments, it was found that under specific conditions, it can substitution react with a variety of nucleophiles to generate a series of derivatives with potential application value.
    At the development level, consider its application potential in the field of materials science. It is envisaged that the preparation of new functional materials may improve the stability, corrosion resistance and other properties of the material. And it may also provide new ideas for the design of lead compounds in medicinal chemistry. I will continue to study it, hoping to expand the application range of this substance and contribute to the development of the chemical field.
    Toxicity Research
    The research on the toxicity of 2, 4, 6 - Trifluorobenzene - 1 - Sulfonyl Chloride is a top priority. In the past, all kinds of poisons, either invisible or found in Russia, were very harmful. Today, this compound also needs to be carefully observed.
    The color state and smell of this substance are the beginning of research. Although you need to be careful when you touch it and smell it, it is also the way to know its nature. Its dissolution and reaction in different media are all related to toxicity. If it encounters water, whether there is gas escape or not, and whether there is a change in heat, it cannot be ignored.
    And consider its impact on various organisms. Take insects, plants and trees, and try them out. Observe the behavior of insects, and observe the prosperity and decline of plants and trees. If insects are restless and sluggish, and plants and trees wither and wither, then you can know the intensity of their toxicity.
    Furthermore, consider its state of diffusion and decomposition in the environment. Whether it can survive in soil and water, and what is the nature of the decomposed material. Only by exploring in detail can we know the circulation of its toxicity in the world, which is the foundation for protection and governance.
    Future Prospects
    Prospects of the future, in 2,4,6 - Trifluorobenzene - 1 - Sulfonyl Chloride This compound is of great importance. Today's researchers are studying its properties, exploring its uses, and hoping to make breakthroughs.
    In this way, this compound can be used to achieve a large-scale display in various fields and achieve unparalleled success.
    Where to Buy 2,4,6-Trifluorobenzene-1-Sulfonyl Chloride in China?
    As a trusted 2,4,6-Trifluorobenzene-1-Sulfonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2,4,6-Trifluorobenzene-1-Sulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,4,6-trifluorobenzene-1-sulfonyl chloride?
    The main use of 2% 2C4% 2C6-tribromobenzene-1-sulfonate bromine is that it plays a crucial role in the field of organic synthesis.
    As a key intermediate in the preparation of dyes, it can combine with a variety of organic compounds through a series of chemical reactions to construct dye molecules with specific structures and properties. With its unique chemical structure, it can endow dyes with excellent color stability, vividness and good dyeing properties, so that fabrics or other materials can show a brilliant and lasting color after dyeing.
    In the field of pharmaceutical research and development, it plays a role that cannot be ignored. It can act as a starting material or an important intermediate, and can be converted into compounds with specific pharmacological activities through carefully designed synthetic routes. With its chemical properties, it can introduce key functional groups, thereby regulating the activity, solubility and biocompatibility of molecules, etc., providing an important material basis for the creation of new drugs.
    In the field of pesticide synthesis, 2% 2C4% 2C6-tribromobenzene-1-sulfonate bromine also has important applications. It can be used to synthesize pesticide products with high insecticidal, bactericidal or herbicidal properties. Its chemical structure helps to interact with specific targets in pests, pathogens or weeds, interfering with their normal physiological metabolic processes, so as to achieve the purpose of controlling pests and ensuring the healthy growth and yield of crops.
    In summary, 2% 2C4% 2C6-tribromobenzene-1-sulfonate bromine has shown indispensable value in many important fields of organic synthesis due to its unique chemical properties, providing strong material support and technical support for the development of many industries.
    What are the physical properties of 2,4,6-trifluorobenzene-1-sulfonyl chloride?
    2% 2C4% 2C6-tribromo-1-chlorofluorane is an organic compound. Its physical properties are as follows:
    This substance is mostly liquid at room temperature and pressure, with a certain volatility. Looking at its appearance, it is often colorless and transparent, like clear water, and its radiant luster can be seen under light. Its smell is specific, although not pungent and intolerable, it is also different from common odorless liquids, with a slightly special smell, which can be identified.
    The density is heavier than water. If mixed with water, it will sink underwater. The two are layered and well-defined. The boiling point is in a specific range, and when heated to this temperature, the liquid state gradually changes to the gaseous state, and the physical state changes.
    Solubility is also one of its important physical properties. In organic solvents, such as ethanol and ether, it is quite soluble, and the two can blend with each other and mix as a whole. However, in water, the solubility is very small, just like oil dripping into water, it is difficult to blend.
    In addition, the physical properties such as surface tension and viscosity of 2% 2C4% 2C6-tribromo-1-chlorofluorocarbons also have their own unique characteristics. The surface tension makes the liquid surface resemble an elastic film, which has an important impact on its contact with foreign objects and the maintenance of morphology. Viscosity is related to the ease with which the liquid flows. The viscosity of this substance is moderate, and it is neither smooth as clear water nor stagnant and difficult to move like glue.
    What are the chemical properties of 2,4,6-trifluorobenzene-1-sulfonyl chloride?
    The chemical properties of 2% 2C4% 2C6 -tribromoaniline-1 -sulfonic acid are unique and play a key role in many fields. It is described in detail in ancient sayings.
    This compound is acidic. The presence of sulfonic acid groups (-SO and H) allows it to partially ionize hydrogen ions (H) in water, so it is acidic. If it encounters a base, a neutralization reaction can occur. Taking sodium hydroxide (NaOH) as an example, the reaction between the two generates the corresponding salt and water, which is a typical acid-base neutralization. The chemical equation is: 2,4,6-tribromoaniline-1-sulfonic acid + NaOH → 2,4,6-tribromoaniline-1-sodium sulfonate + H 2O O. This reaction is like a harmony of yin and yang, and the acidic nature of the sulfonic acid interacts with the alkaline nature of the base to achieve a new equilibrium.
    Its solubility also has characteristics. Because the sulfonic acid group is a hydrophilic group, it has a certain solubility in polar solvents such as water. However, there are still hydrophobic parts such as phenyl rings and bromine atoms in the molecule, so its solubility is not very high. In organic solvents, depending on the polarity of the solvent, the solubility also varies. Polar organic solvents have relatively good solubility to it, while non-polar organic solvents are more difficult to dissolve.
    2% 2C4% 2C6-tribromoaniline-1-sulfonic acid has high reactivity. Sulfonic acid groups can participate in a variety of substitution reactions. For example, under specific conditions with alcohols, the hydroxyl group (-OH) in the sulfonic acid group can be replaced by the alkoxy group (-OR) to form a sulfonate. This reaction is like an exchange dance between atoms and groups, each in place to form a new compound. The bromine atom on the benzene ring, although relatively stable, can also undergo substitution reactions under specific reagents and conditions, introducing other functional groups, opening up various paths for organic synthesis.
    In addition, the compound also shows performance in redox reactions. The sulfonic acid group is in a higher oxidation state, and under the action of a strong reducing agent, a reduction reaction may occur, and the structure of the sulfonic acid group changes. At the same time, the substituents on the benzene ring also affect its redox properties, and different substituents will make the compounds have different sensitivities to redox reagents.
    In summary, the chemical properties of 2% 2C4% 2C6-tribromoaniline-1-sulfonic acid are rich and diverse. In the fields of organic synthesis and materials science, it is like a delicate key that opens the door to many chemical reactions and helps the progress of scientific research and industrial production.
    What are the preparation methods of 2,4,6-trifluorobenzene-1-sulfonyl chloride?
    To prepare 2,4,6-tribromo-1-nitrobenzene, the method is as follows:
    First take an appropriate amount of benzene, mix the acid with concentrated sulfuric acid and concentrated nitric acid, and at a suitable temperature (about 50-60 ℃), make the benzene co-heat with it, and perform a nitrification reaction to obtain nitrobenzene. This step needs to pay attention to temperature control to prevent side reactions. The reaction formula is: $C_ {6} H_ {6} + HNO_ {3} (concentrated) \ xrightarrow [50 - 60 ℃] {concentrated sulfuric acid} C_ {6} H_ {5} NO_ {2} + H_ {2} O $. Next, the obtained nitrobenzene is dissolved in a suitable solvent, such as carbon disulfide, and then at low temperature (0-5 ° C) and catalyzed by iron powder, bromine is slowly introduced to carry out bromination reaction. The capping nitro group is the meta-localization group, so the bromine atom mainly replaces the hydrogen atom of the nitro meta-position to obtain 2,4,6-tribromo-1-nitrobenzene. The reaction formula is: $C_ {6} H_ {5} NO_ {2} + 3Br_ {2}\ xrightarrow [0 - 5 ° C] {Fe} C_ {6} H_ {2} Br_ {3} NO_ {2} + 3HBr $. After the
    reaction is completed, 2,4,6-tribromo-1-nitrobenzene can be obtained by conventional separation and purification methods, such as extraction, distillation, recrystallization, etc., to remove its impurities. The extractor uses the difference in solubility of the solute in incompatible solvents to separate the mixture; distillation is based on the different boiling points of each component; recrystallization is based on the difference in solubility of the substance at different temperatures, so that the solute is precipitated and purified.
    What are the precautions for storing and transporting 2,4,6-trifluorobenzene-1-sulfonyl chloride?
    2%2C4%2C6-%E4%B8%89%E6%B0%9F%E8%8B%AF-1-%E7%A3%BA%E9%85%B0%E6%B0%AF, it is commonly used in chemical industry. During storage and transportation, many matters cannot be ignored.
    The first to bear the brunt, the storage place must be dry and well ventilated. This substance is afraid of moisture. If it is in a humid place, the quality may change and the efficiency will be damaged. And if the ventilation is not good, harmful gases will easily accumulate, endangering the surrounding environment and personal safety.
    Furthermore, the choice of container is very important. Special equipment is required to resist its corrosion and have good sealing performance. If the container leaks, not only will the material be lost, but also the environment will be polluted, and even more, it may lead to safety.
    When transporting, there are also many precautions. It needs to be properly packaged in accordance with the regulations to ensure that it is stable on the way and will not fall over or collide. Transportation vehicles should be equipped with corresponding protective and emergency equipment for emergencies. The escort must be familiar with its nature, know its danger, and be able to handle it properly in case of emergencies.
    In addition, whether it is storage or transportation, it should strictly abide by the relevant regulations, and there should be no slack. The logo should be clear and clear, indicating the danger, so that the contact can be alerted. And the storage and transportation records should also be detailed for traceability and supervision.
    In short, the storage and transportation of 2%2C4%2C6-%E4%B8%89%E6%B0%9F%E8%8B%AF-1-%E7%A3%BA%E9%85%B0%E6%B0%AF is related to safety and quality, and must not be taken lightly. Everything needs to be done with caution.