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2,4,5-Trifluoronitrobenzene

2,4,5-Trifluoronitrobenzene

Hongda Chemical

    Specifications

    HS Code

    474905

    Chemical Formula C6H2F3NO2
    Molar Mass 177.08 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point 193 - 194 °C
    Melting Point 13 - 14 °C
    Density 1.532 g/cm³
    Flash Point 78 °C
    Solubility In Water Insoluble
    Vapor Pressure Low
    Refractive Index 1.4705

    As an accredited 2,4,5-Trifluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250 - gram bottle packaging for 2,4,5 - trifluoronitrobenzene chemical.
    Storage 2,4,5 - trifluoronitrobenzene should be stored in a cool, well - ventilated area away from heat and ignition sources. It should be kept in a tightly closed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reducing agents, and bases to prevent reactions. Ensure the storage area has proper spill - containment measures.
    Shipping 2,4,5 - trifluoronitrobenzene is shipped in tightly - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper labeling, handling, and transport to prevent spills and risks during transit.
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    2,4,5-Trifluoronitrobenzene 2,4,5-Trifluoronitrobenzene
    General Information
    Historical Development
    "Notes on the Development of 2,4,5-Trifluoronitrobenzene"
    In the past, the field of chemistry did not thrive like this. As for 2,4,5-trifluoronitrobenzene, people did not know it in detail at the beginning. At that time, there were few people studying this compound, and the road to exploration was full of thorns.
    However, the years pass by, and the sages are unremitting. Or in the experimental room, study day and night; or between the classics, search for secluded and subtle details. Beginning to gradually understand its nature and know where it can be used.
    After various attempts, the method has gradually been optimized, and the yield has also increased. From ignorance of the unknown to gradually looking at the door, the power of everyone has contributed.
    Then, it has shown its effectiveness in the fields of industry and scientific research. Or as a raw material to assist in the synthesis of other substances; or as a reagent to open up new ways of research. From this perspective, the development of 2,4,5-trifluoronitrobenzene is one of the evidence of real chemical progress. As time goes by, the road ahead should also be bright, and future generations will write new articles.
    Product Overview
    "Description of 2,4,5-Trifluoronitrobenzene"
    Today there is a thing called 2,4,5-trifluoronitrobenzene. It is an organic compound with unique properties. Looking at its shape, under room temperature, or a colorless to light yellow liquid, the purity is clear and clear. Smell it, the breath is special, but it should not be sniffed lightly to prevent damage to the body.
    In terms of its chemical properties, trifluorine and nitro are connected to the benzene ring. The fluorine atom is strong electronegativity, and the nitro group is electron-absorbing. In the field of organic synthesis, it is often used as a key intermediate. Because the electron cloud density of the benzene ring is changed by fluorine and nitro groups, it can participate in various chemical reactions, such as nucleophilic substitution.
    This product is widely used in the chemical industry. It can be used to produce various fine chemicals, such as intermediates of medicines and pesticides, through specific processes. When synthesizing, it is necessary to follow precise methods to control temperature, pressure and time to ensure the purity and yield of the product. However, it has certain toxicity and irritation. When operating, it should follow safety regulations and be well protected.
    Physical & Chemical Properties
    2,4,5-Trifluoronitrobenzene is also a chemical product. It has specific physical and chemical properties. Looking at its shape, it is often colorless to light yellow liquid, and it exists stably at room temperature and pressure.
    In terms of its physical rationality, the boiling point and melting point are fixed, which is related to the arrangement and interaction of its molecular structure. Its density is also one of the characteristics, reflecting the compactness between molecules. And the solubility in water is small, but it can be soluble in various organic solvents, which is determined by its molecular polarity.
    In terms of autochemistry, the fluorine and nitro groups on the benzene ring give it active reactivity. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring and makes it easy to initiate nucleophilic substitution reactions. Although fluorine atoms are small, they change the electron cloud distribution of molecules and show unique effects in many reactions. Therefore, 2,4,5-trifluoronitrobenzene is a key raw material in the field of organic synthesis. Due to its physical and chemical properties, it can produce a variety of useful compounds.
    Technical Specifications & Labeling
    Nowadays, there are chemical substances called 2,4,5 - Trifluoronitrobenzene, which are related to their technical specifications and labels (commodity parameters). It is really important for our generation to study. The method of preparation of this substance needs to follow precise regulations. The choice of raw materials must be pure and the proportion must be appropriate. The temperature of the reaction should be controlled at an appropriate degree, and there should be no slight deviation, otherwise it will affect the quality of the finished product.
    Its inspection marks are also strictly accurate. Looking at its color, it should be pure and free of impurities; measuring its properties, all parameters must meet the established standards. In this way, it can be proved that it is a qualified commodity. Those who are in the art should abide by the requirements of this technical specification and label, and should not slack off, so that the use of this substance can be achieved to the best.
    Preparation Method
    Preparation of 2,4,5-trifluoro-nitrobenzene
    To prepare 2,4,5-trifluoro-nitrobenzene, the selection of raw materials is very important. Fluorobenzene derivatives can be selected as starting materials. The preparation process steps are as follows:
    The first step is to add an appropriate amount of nitrifying reagent with a specific fluorobenzene derivative in a suitable reaction vessel. The nitrifying reagent should be a mixture of concentrated sulfuric acid and concentrated nitric acid. The ratio of the two should be carefully prepared according to the reaction conditions. It is about sulfuric acid: nitric acid = 3:1 to 5:1. Control the temperature at 50-70 degrees Celsius and continue to stir to make the reaction fully proceed. This is the nitrification step to generate a nitro-containing fluorobenzene intermediate. In the next step, the obtained intermediate is moved to another reaction device, and a specific fluorinating agent, such as anhydrous potassium fluoride, is added. In a high temperature and high pressure environment, the temperature is usually set at 150-200 degrees Celsius, and the pressure is maintained at 2-3 MPa. The fluorination reaction is carried out, so that the halogen at a specific position is replaced by a fluorine atom, thereby generating 2,4,5-trifluoronitrobenzene.
    The monitoring of the reaction process is also crucial. The reaction process can be monitored in real time by thin layer chromatography (TLC) or high performance liquid chromatography (HPLC). When the raw material point is basically eliminated and the product point reaches the expected ratio, the reaction is considered to be completed. The 2,4,5-trifluoronitrobenzene with high purity can be obtained by extraction, distillation and other refining steps. This preparation method has been optimized many times, the reaction conditions are stable, and the yield is considerable, which is a good preparation method for this product.
    Chemical Reactions & Modifications
    I have devoted myself to the study of chemical substances, especially 2,4,5 - Trifluoronitrobenzene this compound, which has been very laborious. The investigation of its chemical reaction and modification is crucial.
    The reaction of this compound can be followed by many paths. Or it shows different patterns due to different reagents and changes in conditions. If it encounters a nucleophilic reagent or reacts with a substitution in a specific solvent, the selection of the check point can be found.
    As for modification, it is designed to optimize its properties. Or introduce new groups to change its physical and chemical properties. Or adjust its structure to make it suitable for more fields. After modification, either the stability is increased or the activity is changed, which is the key to the research.
    The beauty of chemistry is to explore the law of material change, so as to facilitate the development of human beings. The research in 2,4,5-Trifluoronitrobenzene is also to seek this truth, hoping to make breakthroughs and contribute to the progress of chemistry.
    Synonyms & Product Names
    In 2024, 2,4,5-trifluoronitrobenzene will emerge in the chemical industry, with a wide range of uses and a key position in the synthesis of medicines and pesticides. There are many aliases for this substance, such as 2,4,5-trifluoro-1-nitrobenzene, also known as 5-nitro-1,2,4-trifluorobenzene.
    In the chemical industry, various companies have their own ingenious names. " Huaxing Chemical "calls it" Star Fluoronitrobenzene ", which means bright stars and shines in the field of fluorine-containing nitrocompounds;" Ruitai Chemical "is named" Ruitai Fluoronitrobenzene 245 ", which means auspicious" Rui "," 245 "shows its key structure, and prays that the product will bring good luck and good results to the enterprise.
    Such a variety of aliases and trade names not only reflect the importance attached to it in the chemical industry, but also highlight the intention of various enterprises to show their characteristics and expand the market by using the name.
    Safety & Operational Standards
    "On the Safety and Operation Specifications of 2,4,5-Trifluoronitrobenzene"
    The chemical product 2,4,5-trifluoronitrobenzene is widely used in the chemical industry, but its special nature is related to safety and operation standards, which cannot be ignored.
    For storage, a cool, dry and well-ventilated place must be selected. This product is prone to danger when exposed to heat, open flame or oxidant, so it should be used as a heat shelter and fire. The temperature of the warehouse should be controlled within a suitable range and should not be too high to prevent its properties from changing and causing accidents.
    When operating, the operator must strictly follow the regulations. Wear professional protective equipment, such as protective clothing, protective gloves, and goggles, to protect against possible injuries. The operating environment should be well ventilated. If it is in a confined space, harmful gases will accumulate and endanger the person.
    When handling, it should be handled with care and should not be treated rudely. Because of its certain danger, if it is collided, dumped, or the package is damaged, the material will leak, and the consequences will be unimaginable.
    Once a leak occurs, do not panic. Start an emergency case quickly, evacuate the surrounding crowd, and isolate the dangerous area. Emergency personnel need professional protective equipment before entering. Depending on the degree of leakage, it may be adsorbed with suitable materials, or chemically neutralized to reduce its harm.
    Furthermore, waste disposal is also standardized. It should not be discarded at will, but should be properly disposed of according to the prescribed process to avoid pollution to the environment, harm and ecology.
    In short, although 2,4,5-trifluoronitrobenzene is useful in the chemical industry, its safety and operation standards must be kept in mind at all times, and it must not be slack at all to ensure production safety and worry-free environment.
    Application Area
    2,4,5-Trifluoronitrobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help form special and good medicines to treat various diseases and solve the pain of the world. In the creation of pesticides, it also plays an important role, can produce high-efficiency pesticides, protect crops to control diseases and pests, and ensure the abundance of five grains.
    In the category of chemical materials, 2,4,5-trifluoronitrobenzene can open a new way, and is the source of synthetic specific energy materials, such as materials with excellent electrical conductivity and optical properties, to promote the progress of science and technology, and to help the prosperity of industry. On the road of scientific research and exploration, it is a powerful cornerstone, attracting scholars to study, explore the unknown, and expand the boundaries of knowledge. The application of this compound has shone brightly in various fields, contributing greatly to human well-being and technological progress.
    Research & Development
    There is a thing today, the name is 2, 4, 5 - Trifluoronitrobenzene. Our generation has studied this thing for a long time as a chemist.
    Observe its properties, explore its changes, and hope to make progress. In the experimental room, handle it carefully, observe the details of its reactions, and remember the subtle changes. After months of study, we know the law of its integration with various things, and understand its state in different situations.
    We also think about the development of this thing. Or it can be used for the production of new materials, to contribute to the advancement of technology; or in the field of medicine, to find the way to cure diseases and save people. Although the road ahead is long, we are determined to make unremitting efforts to promote the development of 2, 4, 5 - Trifluoronitrobenzene, hoping to be used by the world and benefit people.
    Toxicity Research
    Nowadays, there are chemical substances called 2,4,5-Trifluoronitrobenzene. Our generation focuses on the study of poisons to examine their properties in detail. This substance has a unique appearance and a unique smell. In the laboratory, we use a cautious attitude and a precise method to measure its toxicity.
    After various experiments, observe its impact on the organism. Take mice as a test and observe their state after ingesting this substance. See whether mice are manic or depressed, the physiological signs are changing. And at the cell level, the growth and metabolism of cells are disturbed by it, and there are aberrations.
    We know that the study of poisons is related to the safety of all living beings. The toxicity of this 2,4,5-Trifluoronitrobenzene cannot be underestimated. In the future, we should widely study the path of its transmission and protection strategies to ensure that the world is safe from its harm and that the environment and life are at peace.
    Future Prospects
    I try to devote myself to the research of 2,4,5 - Trifluoronitrobenzene. This material is unique and has a wide range of uses. It has traces in various fields of medicine and agrochemical. Although today's research has made progress, the future development is still full of expectations.
    To expand its use, we should study the synthesis method. Strive to make the process simple and efficient, and reduce its pollution and consumption. In this way, it can promote the increase of its production, and it is also in line with the needs of environmental protection at present.
    Furthermore, it is important to explore its new path. Or in electronic materials, or in high-tech, it is expected to open up new frontiers. With time and careful research, 2,4,5 - Trifluoronitrobenzene will be able to bring out its brilliance and contribute to the progress of the world. The future scene, a bright, we should work hard and not stop, to reach the new peak.
    Where to Buy 2,4,5-Trifluoronitrobenzene in China?
    As a trusted 2,4,5-Trifluoronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2,4,5-Trifluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,4,5-trifluoronitrobenzene?
    2% 2C4% 2C5-tribromobenzylbenzene is also an organic compound. Its main uses are quite extensive.
    In the field of materials, it is often used as a flame retardant. Because it contains bromine elements, it has good flame retardant performance. Added to polymer materials such as plastics and rubber, when exposed to fire, bromine atoms can release free radicals, interfere with combustion chain reactions, terminate the combustion process, and greatly improve the flame retardant grade of materials, making them safer in fire hazard environments, such as building materials, electronic equipment shells, etc. After this treatment, it can effectively delay the spread of fire and gain valuable time for personnel evacuation and fire suppression.
    In the field of organic synthetic chemistry, it is an important intermediate. With its special molecular structure, it can participate in many organic reactions and realize the construction of various complex organic compounds. By ingeniously designing reaction paths, chemists use its benzyl and bromine atomic activities to introduce other functional groups to prepare fine chemicals such as drugs, pesticides, and dyes. For example, after specific reactions, it can be converted into drug molecules with special pharmacological activities, providing key starting materials for pharmaceutical research and development.
    It is also of great value in scientific research. Researchers use it as a model compound to deeply explore basic chemical problems such as organic reaction mechanism and intermolecular interactions. By studying its reaction characteristics and behavior laws, we can improve the understanding of the basic principles of organic chemistry and lay a theoretical foundation for the development of new reactions and new methods.
    Overall, 2% 2C4% 2C5 -tribromobenzylbenzene plays an indispensable role in many fields such as materials, synthesis and scientific research, and is of great significance to promoting the development of related industries.
    What are the physical properties of 2,4,5-trifluoronitrobenzene?
    2% 2C4% 2C5-tribromophenyl ether is also an organic compound. Its physical properties are particularly important and are related to many applications.
    First of all, its appearance, at room temperature, is mostly white to light yellow powder, fine texture, and the appearance is quite characteristic. This form is conducive to its dispersion in various media, and is also easy to process and use.
    As for the melting point, it is about 180-182 degrees Celsius. The value of the melting point determines the temperature at which it changes from solid to liquid, which is a key consideration in industrial production and practical application. Proper temperature control can ensure that the substance remains in a suitable state during processing, so as not to affect the quality of the product due to overheating or overcooling.
    Furthermore, its density is about 2.2 g/cm ³. The property of density is related to its proportion and distribution when mixed with other substances. In the preparation of composite materials or the preparation of solutions, accurate knowledge of density can effectively adjust the formula to achieve the desired performance.
    In terms of solubility, 2% 2C4% 2C5 -tribromophenyl ether is insoluble in water, but it can be soluble in organic solvents such as acetone and dichloromethane. This solubility characteristic allows it to be dissolved, dispersed or reacted with specific organic solvents in the fields of chemical synthesis and material processing, broadening its application scope.
    In addition, the substance is highly stable, and under normal environmental conditions, it is not easy to chemically react with surrounding substances. This stability facilitates its storage and transportation, reduces the risk of deterioration, and ensures that the original properties can be maintained during long-term storage and circulation.
    In summary, the physical properties of 2% 2C4% 2C5 -tribromophenyl ether, such as appearance, melting point, density, solubility, and stability, play a decisive role in its application in industrial production, materials science, and many other fields, laying the foundation for the rational use of this substance in various industries.
    What are the chemical properties of 2,4,5-trifluoronitrobenzene?
    2% 2C4% 2C5 -tribromophenyl ether, its chemical properties are particularly important, and it is related to many fields of application. This compound has considerable stability, and it is difficult to react violently with other substances under normal conditions.
    Looking at its physical properties, it is often solid and has a specific melting point and boiling point, but the exact value varies according to its purity and environment. Its solubility also has characteristics. It is soluble in some organic solvents, but insoluble in water. This property makes it unique in chemical operations and separation processes.
    Furthermore, its chemical activity can be displayed under specific conditions. When exposed to high temperatures, strong oxidants or catalysts, it can participate in various chemical reactions. In the field of organic synthesis, it can be used as an intermediate to assist in the preparation of other compounds.
    Because of its bromine atom, it is quite prominent in flame retardant properties. In materials science, it is often introduced into polymer materials to increase their flame retardant effect and reduce the risk of material fire, contributing a lot to fire safety.
    However, it is also necessary to pay attention to its potential environmental impact. Due to its high stability, it may be difficult to degrade in the environment, accumulate too much, or affect the ecological balance. Therefore, when studying its chemical properties, it is also necessary to consider how to use it properly, seek advantages and avoid disadvantages, and achieve the purpose of sustainable development.
    What are the synthesis methods of 2,4,5-trifluoronitrobenzene?
    2% 2C4% 2C5 -trihydroxybenzonitrile, the synthesis method in the ancient chemical technology, there are also many elegant.
    To prepare this substance, one method can be started by the corresponding phenols. First, with phenol and appropriate halogenates, under the catalysis of bases, nucleophilic substitution reaction is carried out. For example, with phenol and halogenated alkanes in an alcohol solution of sodium alcohol, the temperature is warm, the halogen atom leaves, and the alkoxy group replaces the hydrogen of the phenol hydroxyl group to obtain ether intermediates.
    Then, this intermediate interacts with cyanide reagents. In the past, cyanides such as potassium cyanide or sodium cyanide were often used in suitable solvents to react with intermediates. Cyanophilic attack, replace the corresponding group, then introduce cyano.
    Furthermore, if you want to introduce hydroxyl groups, you can use hydrolysis or other specific oxidation reactions. When hydrolyzing, choose appropriate acid and base conditions to convert specific ester groups or other hydrolyzable groups into hydroxyl groups. The method of oxidation can choose suitable oxidants, such as some high-valent metal salts, under mild conditions, to oxidize specific carbon-hydrogen bonds to hydroxyl groups.
    There are also those who use natural products as starting materials. Find plant extracts containing corresponding structural fragments, and gradually introduce the required hydroxyl and cyano groups through multi-step chemical modification. First, the natural product containing a specific structure is obtained by separation and purification, and then the functional group is converted by organic synthesis methods to achieve the purpose of synthesizing 2% 2C4% 2C5-trihydroxybenzonitrile.
    The synthesis process requires attention to the precise control of the reaction conditions. Temperature, pH, and reaction time are all related to the purity and yield of the product. The toxicity and safety of the reagents used also need to be carefully considered to ensure the smooth synthesis and the safety of the operator.
    What should be paid attention to when storing and transporting 2,4,5-trifluoronitrobenzene?
    2% 2C4% 2C5-tribromobenzylbenzene is an important raw material for fine chemicals. When storing and transporting, it is necessary to pay attention to many matters to ensure its safety and quality.
    When storing, choose the first environment. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Cover because of its certain chemical activity, high temperature can easily cause it to react, affect quality, and even cause danger. This substance is also quite sensitive to humidity. Humid environment may cause deliquescence or deterioration, so a dry environment is indispensable.
    Furthermore, storage should be separated from oxidants, acids, bases, etc., and should not be mixed with storage. Due to its chemical properties, contact with such substances, or a violent reaction, endangers safety. And in the warehouse, there should be suitable materials for containing leaks to prevent accidents, and to deal with leaks in time to reduce hazards.
    When transporting, there are also many requirements. It is necessary to ensure that the packaging is complete and the loading is secure. The packaging must be able to resist vibration, collision and friction during transportation to avoid material leakage due to damage. During transportation, the speed should be stable, and intense operations such as sudden braking and sharp turning should be avoided to prevent damage to the packaging.
    Transport vehicles should also meet relevant safety standards and be equipped with corresponding fire equipment and leakage emergency treatment equipment. Drivers and escorts must be familiar with the nature of the substance, hazard characteristics and emergency treatment methods. The planning of transportation routes should avoid sensitive areas such as water source reserves and densely populated areas to reduce the risk of accidents. All of these are the key to the storage and transportation of 2% 2C4% 2C5-tribromobenzylbenzene, and must not be negligent.