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2,4,5-Trifluorobenzenesulphonyl Chloride

2,4,5-Trifluorobenzenesulphonyl Chloride

Hongda Chemical

    Specifications

    HS Code

    349901

    Name 2,4,5-Trifluorobenzenesulphonyl Chloride
    Molecular Formula C6H2ClF3O2S
    Molecular Weight 230.59
    Appearance Typically a colorless to light yellow liquid
    Boiling Point Around 225 - 227 °C
    Density Data may vary, but in the range of common sulfonyl chlorides
    Solubility Soluble in many organic solvents like dichloromethane, chloroform
    Pungency Highly pungent and irritating odor
    Reactivity Reactive towards nucleophiles, reacts with amines, alcohols

    As an accredited 2,4,5-Trifluorobenzenesulphonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 2,4,5 - trifluorobenzenesulphonyl Chloride in a sealed chemical - grade bottle.
    Storage 2,4,5 - trifluorobenzenesulphonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat sources and direct sunlight. It must be kept in a tightly sealed container to prevent moisture ingress, as it is reactive with water. Store it separately from incompatible substances like bases, reducing agents, and reactive metals to avoid potential hazardous reactions.
    Shipping 2,4,5 - trifluorobenzenesulphonyl chloride is a chemical that must be shipped with care. It should be in a well - sealed, corrosion - resistant container, following all hazardous chemical shipping regulations to prevent leaks and ensure safe transit.
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    2,4,5-Trifluorobenzenesulphonyl Chloride 2,4,5-Trifluorobenzenesulphonyl Chloride
    General Information
    Historical Development
    The history of 2,4,5-trifluorobenzenesulfonyl chloride
    Fu 2,4,5-trifluorobenzenesulfonyl chloride is also an important agent in organic synthesis. At the beginning of its inception, it was the result of the research and exploration of the field of chemistry by the sages. At that time, the chemical skills were not as exquisite as they are today, but the public was determined to seek the truth among the numerous experiments.
    At the beginning, the preparation of this agent was difficult. The finding of raw materials and the control of the reaction conditions were all difficult problems. However, chemists tried again and again with the spirit of perseverance. After years of hard work, they gradually obtained the method of preparation, and the process was also perfected day by day.
    From the past to the present, 2,4,5-trifluorobenzenesulfonyl chloride has gradually shown its function in various fields such as medicine and materials. Assist in the research and development of medicine, make special drugs; innovate auxiliary materials, and create novel materials. The evolution of its history is actually a microcosm of the development of chemistry, witnessing the wisdom and perseverance of all sages, leaving valuable experience for future chemical research.
    Product Overview
    Today there is a substance called "2,4,5 - Trifluorobenzenesulphonyl Chloride". This is a chemical raw material, which is quite useful in the field of organic synthesis. It is active and can react with many compounds to form other organic substances.
    Looking at its shape, at room temperature, it may be a colorless to light yellow liquid with a stimulating odor. Its physical properties, such as boiling point, melting point, density, etc., have specific numbers, which can be identified and isolated.
    This compound is often a key intermediate in the synthesis of medicines, pesticides and fine chemicals. With its activity, specific functional groups can be introduced to give the product special properties. However, because of its liveliness, it is necessary to be cautious and strictly abide by the procedures during operation to ensure safety. In summary, "2,4,5 - Trifluorobenzenesulphonyl Chloride" is an indispensable material for chemical research and development.
    Physical & Chemical Properties
    Today there is a thing named "2,4,5 - Trifluorobenzenesulphonyl Chloride". Its physical and chemical properties are relevant to our research.
    The state of this thing, whether it is a specific shape, a liquid, or a solid at room temperature, needs to be carefully investigated. Its color, whether clear or different, also needs to be carefully observed. As for its taste, its unique smell can be known by smelling.
    Its chemistry, whether it is active or not, and how it responds to various things are all key. When it comes into contact with water, it is necessary to know why the product is, and the urgency of the reaction. In the environment of acid and alkali, the changes should also be studied in depth. This is to gain insight into its physical and chemical properties, so as to facilitate future use, improve control, and contribute to the progress of scientific research.
    Technical Specifications & Labeling
    There is now a product named 2,4,5-trifluorobenzenesulfonyl chloride. In the process specification and identification (product parameters), it is very important. The process specification needs to specify the preparation method, from the selection of raw materials, the accurate ratio, to the reaction conditions, such as temperature, pressure, and duration, all must be detailed. The reaction steps are orderly and must not be disordered, and the treatment of intermediate products should not be neglected.
    Regarding the identification (product parameters), the appearance should state its color, state, or colorless liquid, or white solid. Purity, when shown with accurate data, is related to the quality of the product. In addition, the density, melting point, boiling point and other physical parameters should also be clear for users to follow. In this way, the process specifications and identification (product parameters) of this product can be completed, providing users with accurate guidance.
    Preparation Method
    The method of making 2,4,5-trifluorobenzenesulfonyl chloride is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are trifluorobenzene and chlorosulfonic acid, etc. First, the trifluorobenzene is placed in a special kettle, slowly injected with chlorosulfonic acid, and the temperature is controlled at 50 to 60 degrees. This is the initial step of the reaction.
    During the period, it is necessary to carefully observe the reaction process, and fine-tune the temperature and material injection rate according to its state. The catalytic mechanism uses a specific metal salt as a catalyst to accelerate the reaction and improve the yield. After the reaction is completed, pure 2,4,5-trifluorobenzenesulfonyl chloride is obtained through cooling, separation and purification. In this way, the process is exquisite, and each step needs to be precisely controlled to obtain high-quality products.
    Chemical Reactions & Modifications
    The industry of chemical industry is related to the change of all things. In the study of compounds, it is a delicate way. Today, there are 2,4,5 - Trifluorobenzenesulphonyl Chloride, and the exploration of its chemical reaction and modification is crucial.
    Looking at its reaction, it can be combined with various reagents to form a genus of substitution and addition. However, the control of the reaction conditions is particularly critical. High temperature makes it fast, and then the side effect also increases; low temperature makes it slow, or the reaction is incomplete.
    As for modification, new radicals can be introduced to change its physical properties. Or increase its stability, or change its solubility. In this way, it can be used for expansion, and it is expected to emerge in the field of medicine and materials. Our chemical researchers should study it carefully to make the best use of it and contribute to the progress of the world.
    Synonyms & Product Names
    "Composition"
    Today there is a product called "2,4,5-trifluorobenzenesulfonyl chloride". Its aliases are also many, such as "2,4,5-trifluorobenzenesulfonyl chloride". This chemical product is quite important in the chemical industry.
    "2,4,5-trifluorobenzenesulfonyl chloride", its color or transparent, or light yellow, with an irritating taste. It is often used as a raw material for chemical synthesis. It has a remarkable effect in the preparation of medicine and pesticides.
    In the development of medicine, based on it, it can be used to make special drugs to treat various diseases. In the production of pesticides, it can help to produce high-efficiency insecticides and herbicides to ensure the health of crops.
    Although it is widely used, it is necessary to be careful. Because of its corrosive nature, when operating, follow the rules and prepare protective equipment to ensure personal safety. The way of chemical industry is endless to explore. The wonders of this thing still need to be further studied.
    Safety & Operational Standards
    Specifications for the safety and operation of 2,4,5-trifluorobenzenesulfonyl chloride
    Fu 2,4,5-trifluorobenzenesulfonyl chloride is a commonly used substance in chemical research. During experimental operation, safety is as important as Mount Tai, and the operating specifications must be strictly adhered to.
    This substance is dangerous to a certain extent. It is active and prone to violent reactions in contact with water, so when storing, be sure to store it in a dry, cool and well-ventilated place, away from water sources and moisture. When taking it, you must wear professional protective equipment, such as protective gloves, goggles and protective clothing, to prevent it from coming into contact with the skin and eyes. If you accidentally touch it, you should immediately rinse it with plenty of water and seek medical treatment immediately.
    During the operation, ensure that the experimental environment is well ventilated. Because the reaction may produce harmful gases, good ventilation can be discharged in time to avoid inhalation poisoning by the experimenter. Furthermore, when performing related chemical reactions, be sure to operate according to the exact ratio and specific steps. Read the reaction principle and precautions carefully first, and do not act rashly. For example, when adding this substance to the reaction system, it should be added slowly, and the reaction phenomenon should be closely observed to prevent the reaction from being too violent and out of control.
    After the experiment is completed, the remaining 2,4,5-trifluorobenzene sulfonyl chloride must not be discarded at will. It is necessary to follow the prescribed waste treatment process and dispose of it properly to avoid pollution to the environment. In conclusion, in the research and use of 2,4,5-trifluorobenzenesulfonyl chloride, safety and standardized operation are always involved, which is related to the safety of the experimenter and the success or failure of the research.
    Application Area
    Today there is a product called 2,4,5-trifluorobenzenesulfonyl chloride. This product has its uses in many fields. In the field of medicine, it can be used as a key intermediate to help create new drugs and cure various diseases. In the field of agrochemistry, it can be used as a raw material for synthesizing high-efficiency pesticides, protecting crops and resisting pests and diseases. In the field of materials science, it can participate in the preparation of special materials, giving materials unique properties, such as enhancing their stability and corrosion resistance. This compound has a unique chemical structure and good activity. It is often used by chemists in the art of organic synthesis to build complex and delicate molecular structures and open up new applications. The prospects are broad and limitless.
    Research & Development
    Today's research on this product 2,4,5 - Trifluorobenzenesulphonyl Chloride. At the beginning of the research, I want to understand its nature and explore its preparation method. Examine the classics carefully, and search for alchemy, so I can get one or two paths. After repeated tests, adjust its heat and control its raw materials, and strive for accuracy. During this period, although many obstacles were encountered, or the reaction was not as expected, or the impurities were difficult to remove, I did not give up. After repeated consideration and improvement, the yield gradually increased, and the purity also increased. Looking at this achievement now, it is really a hard work. In the future, we should continue to study and expand its use, hoping to make achievements in various fields, promote its development, and add bricks and tiles to the academic industry, so as to live up to this research.
    Toxicity Research
    Study on the toxicity of 2,4,5-trifluorobenzenesulfonyl chloride
    Taste the chemical industry, there are many substances with different properties, and the research of toxicity is related to safety. Today, 2,4,5-trifluorobenzenesulfonyl chloride is the study.
    This substance is irritating, touches the skin, or causes redness, swelling and burning pain, such as being burned by fire. In the eyes, the tingling is unbearable, and it is very damaging to vision. If you inhale its volatile gas, it will hurt the respiratory tract, cough and chest tightness, and asthma.
    Investigate the root cause of its toxicity, due to the structure of fluorine, sulfur and other elements, the activity is abnormal, and it causes chemical reactions in the body, which is disordered by physiology.
    The purpose of research is to clarify the harm and determine the protective policy. When taking it in production, it is necessary to wear protective equipment, such as masks and gloves, and operate it in a well-ventilated place. If you accidentally touch it, rinse it with water quickly and seek medical treatment. I hope my colleagues will treat it with caution, protect their health and promote the prosperity of the industry.
    Future Prospects
    I Guanfu 2,4,5 - Trifluorobenzenesulphonyl Chloride This product is a treasure of chemical industry, with infinite potential and considerable development in the future. Although it has not yet reached its peak, its prospects are shining, just like the stars.
    In the field of medicine, this product may become the cornerstone of innovative drugs, helping to overcome intractable diseases; in materials science, it is also expected to give birth to new materials to meet the needs of the times. Its unique chemical properties are like keys, which can open the door to future technology.
    Our chemical researchers should study diligently and tap its potential. With time, they will be able to expand their application fields and make them beneficial to the world. On the road to the future, 2, 4, 5 - Trifluorobenzenesulphonyl Chloride will surely shine, lead the transformation of science and technology, and achieve extraordinary things. This is the vision of our generation and the vision of the future.
    Where to Buy 2,4,5-Trifluorobenzenesulphonyl Chloride in China?
    As a trusted 2,4,5-Trifluorobenzenesulphonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2,4,5-Trifluorobenzenesulphonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,4,5-trifluorobenzenesulfonyl chloride?
    2% 2C4% butyl 2C5 trihydroxybenzoate, its main uses are as follows:
    This is an important organic compound, in the industrial field, often used as a plasticizer. The function of plasticizers is to make plastic products more flexible and malleable. In the manufacture of plastic products, adding an appropriate amount of 2% 2C4% butyl 2C5 trihydroxybenzoate can improve the processing performance of plastics, making it easier to flow during the molding process, so as to obtain plastic products with different shapes and good texture, such as films, pipes, artificial leather, etc.
    In the coating industry, it also plays a key role as a solvent and additive. As a solvent, it can effectively dissolve the resin, pigment and other components in the coating, so that the coating can be evenly dispersed, and the coating performance and drying speed can be improved. As an additive, it can enhance the adhesion, water resistance and chemical corrosion resistance of the coating, so that the coating can form a stronger and longer-lasting protective film on the surface of the object. It is widely used in the production of coatings in the fields of construction, automobile, furniture, etc.
    In the field of medicine, 2% 2C4% Butyl 2C5-trihydroxybenzoate can be used as a pharmaceutical excipient. The function of pharmaceutical excipients is to assist in drug molding, improve drug stability and promote drug absorption. In pharmaceutical preparations, it can be used as a coating material to wrap drug particles, control the release rate of the drug, and enable the slow and continuous release of the drug in the body, improve the efficacy of the drug, and reduce the frequency of taking the drug. It can also help improve the stability of the drug, prevent the oxidation and hydrolysis of drug ingredients, and prolong the shelf life of the drug.
    What are the physical properties of 2,4,5-trifluorobenzenesulfonyl chloride?
    2%2C4%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF%E7%9A%84%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8%E5%A6%82%E4%B8%8B%EF%BC%9A
    The oil color of this medicine is clear, first smelled, the aroma is special, fragrant but not greasy, the breath is unique, and it can refresh the spleen. Its texture is warm, smooth but not stagnant to the touch, and it extends freely on the skin. It seems to be able to meet the skin, and it is easy to apply evenly.
    Its density is slightly larger than that of water. When it is poured into the device, it can be seen that it sinks slowly, but it is not like a heavy thing. It is heavy but not turbid. Its fluidity is quite good, and it can flow smoothly on the plane, such as a stream gurgling and meandering.
    And this medicine oil has good solubility. If it drops in some solvents, it can quickly blend with it and become one with each other, regardless of each other. When heated, its properties are stable, it is not easy to evaporate and dissipate, and it can maintain its medicinal power for a long time. When it is cold, it is not easy to solidify, and it can still maintain its flowing state, which is convenient to use.
    The physical properties of this medicinal oil are unique, and it can play an important role in many aspects such as medicine and health care. It can be used for massage and massage to help the medicinal power penetrate the skin; or it can be used for incense health care. With its aroma, it is a good product with a wide range of uses.
    Is the chemical properties of 2,4,5-trifluorobenzenesulfonyl chloride stable?
    The chemical properties of 2% 2C4% 2C5 -tribromobenzoate ethyl ester are the main points of academic research. The stability of the chemical properties of this substance is related to its application in many fields.
    When discussing stability, it is necessary to observe its structure and chemical bonds. 2% 2C4% 2C5 -tribromobenzoate ethyl ester, in its molecular structure, the bromine atom is connected to the benzene ring, which gives the molecule a certain stability. The benzene ring has a conjugated system, and the electron cloud is evenly distributed, which makes the structure tend to be stable. The bromine atom has a high electronegativity. When it is connected to the benzene ring, it affects the electron cloud density of the benzene ring through induction and conjugation effects, and then affects the overall stability.
    However, the stability is not absolute. Under certain conditions, such as high temperature and strong acid-base environment, its chemical bonds may be destroyed. At high temperature, the thermal motion of molecules intensifies, the vibration of chemical bonds is enhanced, or the bond energy is weakened, triggering decomposition reactions. In strong acid and alkali media, acid-base catalysis may promote the hydrolysis of ester groups and break the original stable structure.
    In the field of organic synthesis, the stability of 2% 2C4% 2C5 -tribromobenzoate ethyl ester is both an advantage and a limitation. Its stability can ensure that some structures remain unchanged during the reaction process, which is conducive to the accurate construction of the target product. However, when it is wanted to perform specific functional group transformation, the stability needs to be reasonably regulated. With appropriate reaction conditions and reagents, the stability barrier can be overcome to achieve the expected chemical transformation.
    In summary, the chemical properties of 2% 2C4% 2C5-tribromobenzoate ethyl ester have a certain stability, but they are not static. In different environments and reaction systems, the stability will have different manifestations. This characteristic determines the scope and method of its application in various fields. Chemists need to use and regulate it flexibly according to actual needs.
    What is the synthesis method of 2,4,5-trifluorobenzenesulfonyl chloride?
    To prepare 2% 2C4% 2C5-tribromobenzoic anhydride, the method is as follows:
    First take 2% 2C4% 2C5-tribromobenzoic acid and place it in a clean reaction vessel. This raw material needs to be carefully screened to ensure that the purity is up to standard before it can be used in subsequent reactions.
    Prepare an appropriate amount of dehydrating agent, common such as phosphorus pentoxide, but also acetic anhydride. The amount of dehydrating agent should be precisely prepared according to the reaction scale and stoichiometry. Taking phosphorus pentoxide as an example, it is generally added in a certain molar ratio with 2% 2C4% 2C5-tribromobenzoic acid. This ratio needs to be carefully considered according to the specific reaction conditions, usually between 1:1 and 1:3.
    Seal the reaction vessel well and connect it to a condensing device to prevent the material from escaping during the reaction process. Subsequently, slowly heat it up to make the temperature rise steadily. In the initial stage, the temperature rise should be slow, about 5 to 10 degrees Celsius per minute, to 150-200 degrees Celsius range, to maintain a constant temperature. At this time, closely observe the reaction phenomenon, and it can be seen that the material is gradually melting and the internal reaction is active.
    During the constant temperature process, the dehydrating agent plays a role in promoting the removal of water molecules between 2% 2C4% 2C5-tribromobenzoic acid molecules, thereby forming an anhydride structure. This process requires continuous stirring to allow the reactants to fully contact and speed up the reaction process. The stirring rate is about 200 to 300 revolutions per minute to evenly disperse heat and materials.
    The reaction time is about 2 to 4 hours, during which the progress of the reaction is regularly detected. The remaining amount of raw materials and the formation of the product can be monitored by thin-layer chromatography or other suitable analytical methods. When the raw material conversion rate is as expected, usually greater than 90%, the heating can be stopped.
    After the reaction is completed, the reaction system is naturally cooled to room temperature. Then, the product is carefully removed from the reaction vessel and properly separated and purified. If extracted with an organic solvent and then recrystallized, pure 2% 2C4% 2C5-tribromobenzoic anhydride can be obtained. The whole process requires strict adherence to operating specifications and attention to safety protection in order to obtain the target product smoothly.
    What are the precautions for storing and transporting 2,4,5-trifluorobenzenesulfonyl chloride?
    2% 2C4% 2C5-tribromobenzoate ethyl ester in storage and transportation, need to pay attention to many key matters. This is a chemical, its unique nature, a little careless can cause disaster.
    When storing, the first priority environment. It must be selected dry, cool and well-ventilated place, must not be placed in a humid place, so as not to deteriorate due to moisture erosion. Temperature must also be strictly controlled, too high temperature or cause its chemical changes, endangering safety. Warehouses should be kept away from fire and heat sources, and avoid open flames and hot topics to prevent the risk of fire and explosion.
    Furthermore, storage needs to be classified and divided. 2% 2C4% 2C5 -tribromobenzoate ethyl ester should not be mixed with oxidants, acids, alkalis, etc., because of its active chemical properties, contact with other substances or react violently. And it should be properly packaged to ensure that the packaging is intact and prevent leakage.
    When transporting, there are also requirements. The transport vehicle must meet safety standards and be equipped with corresponding fire and leak emergency treatment equipment. The loading and unloading process must be handled with care. It is strictly forbidden to drop, heavy pressure and friction to avoid packaging damage. During transportation, the condition of the goods should be checked regularly. If there is any abnormality such as leakage, immediate measures should be taken.
    The escort personnel are also crucial, and they need to be familiar with the characteristics of the chemical and emergency treatment methods. Transportation routes should avoid sensitive areas such as water sources and densely populated areas to prevent serious consequences from accidents. Only by strictly observing storage and transportation regulations can the safe circulation of 2% 2C4% 2C5-tribromobenzoate ethyl ester be guaranteed and disasters can be avoided.