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2,4,5-Trifluorobenzenesulfonyl Chloride

2,4,5-Trifluorobenzenesulfonyl Chloride

Hongda Chemical

    Specifications

    HS Code

    419157

    Chemical Formula C6H2ClF3O2S
    Molecular Weight 230.59
    Appearance Typically a colorless to light - yellow liquid
    Boiling Point Specific value depends on pressure, generally in a certain range related to its volatility
    Density Value would be specific to the compound, related to its mass - volume ratio
    Solubility Soluble in some organic solvents, less soluble in water
    Reactivity Reactive towards nucleophiles due to the presence of sulfonyl chloride group
    Purity Can be produced in various purity levels depending on production process
    Odor May have a pungent, characteristic odor

    As an accredited 2,4,5-Trifluorobenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram bottle of 2,4,5 - trifluorobenzenesulfonyl chloride, well - sealed.
    Storage 2,4,5 - trifluorobenzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and incompatible substances such as strong bases, reducing agents. Store in a tightly - sealed container to prevent contact with moisture, which can cause hydrolysis. Avoid long - term exposure to air.
    Shipping 2,4,5 - trifluorobenzenesulfonyl chloride is a chemical that requires careful shipping. It should be packaged in corrosion - resistant containers, transported under cool conditions, and in compliance with all hazardous chemical shipping regulations.
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    2,4,5-Trifluorobenzenesulfonyl Chloride 2,4,5-Trifluorobenzenesulfonyl Chloride
    General Information
    Historical Development
    The industry of chemical industry is changing with each passing day, and new products emerge one after another. Today, there is 2,4,5-trifluorobenzenesulfonyl chloride, whose birth and development also have a tortuous path.
    In the past, the sages of chemical industry paid a lot of attention to the research of sulfonyl chloride. At the beginning, the method of synthesis was explored, but it was difficult to achieve after a hundred trials. Later, there were wise men who had insight into physical properties and repeated deductions, and finally got the clue of synthesis. In the experimental room, all kinds of raw materials were carefully selected, and the reaction conditions were strictly controlled. Or heating, or pressurizing, or adjusting pH, after countless improvements, 2,4,5-trifluorobenzenesulfonyl chloride gradually took shape.
    With the passage of time, the synthesis technology is becoming more and more mature, the yield is gradually increasing, and the quality is also excellent. This compound is gradually showing its ability in the fields of medicine, materials, etc., adding to the progress of various industries, opening a new chapter, and future generations should be researched and further developed to develop infinite possibilities.
    Product Overview
    Today there is a product called "2,4,5 - Trifluorobenzenesulfonyl Chloride". This is a chemical product with unique properties. From the perspective of it, it is a colorless to slightly yellow liquid with a pungent odor.
    It is widely used in the field of chemical synthesis. It is often used as a sulfonylating agent, which can react with a variety of compounds and introduce sulfonyl groups to prepare many organic compounds with special properties. In the process of organic synthesis, the reaction conditions can be precisely controlled to achieve the effective synthesis of the target product.
    The preparation method requires multiple steps of fine operation, according to specific reaction paths and conditions, to obtain this high-purity product. However, when preparing, it must be treated with caution, because it is corrosive and irritating, improper operation, or dangerous. In short, this "2,4,5 - Trifluorobenzenesulfonyl Chloride" is of great value in chemical research and industrial applications.
    Physical & Chemical Properties
    2,4,5-Trifluorobenzenesulfonyl chloride, its material has unique physicochemical properties. Looking at its physical properties, it is usually a colorless to slightly yellow liquid at room temperature. If it is pure, it is clear and has a specific odor. Its boiling point and melting point are both certain. The boiling point can reach a certain value under a specific pressure, and the melting point is also a certain temperature. This is related to the force and structure of its molecules.
    When it comes to chemical properties, the chemical activity of this substance is quite high. The sulfonyl chloride group is very active and easily reacts with many nucleophiles. If it encounters alcohols, it can form sulfonates; if it encounters amines, sulfonamides are formed. Due to its fluorine atoms, fluorine has a large electronegativity, which makes molecular electron clouds unique, resulting in unique chemical stability and reaction selectivity. These physicochemical properties are widely used in the field of organic synthesis and can be the key raw materials for the creation of new compounds.
    Technical Specifications & Labeling
    There is a product today, and the name is "2,4,5-trifluorobenzenesulfonyl chloride". To clarify its technical specifications and identification (product parameters), it is necessary to study in detail.
    The technical specifications of this product are related to its quality. Its purity geometry and impurity content need to be accurately determined. The preparation method should follow strict procedures to ensure constant quality.
    As for the label, its properties, color and taste are the key. On the package, when the name is written, a warning is attached to indicate its dangerous characteristics, such as corrosion, toxicity, etc. Mark the production date and batch for traceability.
    All these, in the "2,4,5-trifluorobenzenesulfonyl chloride" technical specifications and labels are essential and cannot be ignored.
    Preparation Method
    The method of making 2,4,5-trifluorobenzenesulfonyl chloride is related to the raw materials and production process, reaction steps and catalytic mechanism.
    Prepare the raw materials, take the fluorobenzene-containing compounds, and supplement the sulfonation reagents, which are based on the two. At the beginning of the reaction, control the temperature at an appropriate value, and put the raw materials into the reactor in a certain order, stirring to promote it to mix well. In the initial stage, the temperature should be raised slowly, and there should be a reaction trace, and the temperature should be stabilized to make the sulfonation reaction go forward.
    During the reaction steps, closely monitor the system changes, and use instruments to measure key parameters, such as pH, reaction heat, etc. According to the measurement and adjustment of the reaction conditions, the reaction trend
    In the catalytic mechanism, the catalyst is selected to reduce the reaction energy barrier and speed up the reaction process. The amount of catalyst is precisely controlled, more will cause side reactions, and less will not promote the effect. In this way, 2,4,5-trifluorobenzenesulfonyl chloride can be prepared.
    Chemical Reactions & Modifications
    "On the Chemical Reaction and Modification of 2,4,5-Trifluorobenzenesulfonyl Chloride"
    The current research on 2,4,5-trifluorobenzenesulfonyl chloride has significant characteristics in the field of chemical reactions. The reaction of this compound is often unique. If it encounters various reagents, it may cause substitution or addition.
    Its reactivity is related to many factors. Such as the temperature and pressure of the reaction, as well as the properties of the reagents involved, are all key. If you want to make the reaction go smoothly, you must carefully observe all ends and carefully adjust the conditions.
    As for the way of modification, or add the group of functions to change its nature and make it suitable for other ways. Or use the method of catalysis to increase the effect of its reaction.
    After many inquiries, the law of its reaction and the path of modification are gradually clarified, and it is hoped that in the future, it will be applied more widely and better in the chemical industry, so as to benefit the world.
    Synonyms & Product Names
    Today there is a product called "2,4,5-trifluorobenzenesulfonyl chloride". This product has a wide range of uses in the field of chemistry. There are also many synonyms, all of which are well known in the industry.
    The name of the chemical product is complicated, and there are many people with the same product but different names. "2,4,5-trifluorobenzenesulfonyl chloride" is also called by him, but its essence has not changed. These synonyms, either due to differences in regions or due to industry habits, have their own origins.
    As for the name of the product, it also varies according to the needs of different merchants and the market. However, no matter how the name changes, its nature and use are determined. We chemical researchers should be familiar with its many titles in order to work and research without any obstacles and accurately use them, so as to become a scientific research career and contribute to the development of chemistry.
    Safety & Operational Standards
    2,4,5-Trifluorobenzenesulfonyl chloride is an important substance in chemical research. When it is used and operated, it is the first priority to strictly abide by safety and operating standards.
    This substance is dangerous. It can cause significant irritation to the skin, eyes and respiratory tract. If it comes into contact with the skin inadvertently, rinse with plenty of water immediately, then according to the severity of the injury, or treat it yourself, or seek medical treatment. If it enters the eye, rinse thoroughly with plenty of flowing water or normal saline immediately, and be sure to seek medical attention as soon as possible. During the operation, if inhalation of its volatile aerosol can cause respiratory discomfort. At this time, you should quickly go to a place with fresh air. If the symptoms do not subside, you should also seek medical attention.
    In terms of operating specifications, it is appropriate to conduct the experiment in a well-ventilated experimental environment. Experimenters should wear appropriate protective clothing, including laboratory clothes, protective gloves, etc., to prevent skin contact. At the same time, wear protective glasses or masks to protect the eyes from possible splash damage. After use, properly store the substance, seal the container, and place it in a cool, dry and ventilated place away from fire and heat sources to prevent accidents.
    Furthermore, during the experimental operation, the dosage should be precisely controlled and used according to the experimental needs to avoid waste and unnecessary risks. The operating equipment should also be checked in advance to ensure that there is no damage and no leakage, so as to ensure the smooth progress of the experiment and the safety of personnel. In short, when treating 2,4,5-trifluorobenzenesulfonyl chloride, we should follow the safety and operating standards with a rigorous and prudent attitude to ensure the safety of the experiment and promote the progress of the research.
    Application Area
    2,4,5-Trifluorobenzenesulfonyl chloride is also a chemical material. Its application field is quite wide. In the field of medicine, it can be used as the key raw material for synthesizing special drugs, and with its unique chemical properties, it can help form a fine drug body structure to treat various diseases. In the field of materials, it can modify materials, increase their stability, weather resistance, etc., so that the material is suitable for harsh environments. In the field of fine chemicals, it is the cornerstone of the preparation of high-end chemicals, such as special surfactants. This material is like a craftsman's tool, which can be used in various application fields to carve exquisite results, help the development of the chemical industry, and promote scientific and technological progress. It is of extraordinary value in many industries. It is an important means for chemical research and application.
    Research & Development
    Nowadays, there is a chemical substance called 2,4,5 - Trifluorobenzenesulfonyl Chloride. As a chemical researcher, I have paid close attention to its research and development.
    This substance has unique properties and has extraordinary potential in the field of organic synthesis. Its structure is exquisite, and it contains fluorine atoms and sulfonyl chloride groups, which endow it with unique reactivity. Past studies have initially shown its ability to create new compounds.
    However, there are still many challenges to be solved in order to promote its rapid development. The synthesis method needs to be simpler and more efficient in order to reduce costs and increase yields. The study of its reaction mechanism must also be deepened so that the reaction can be precisely regulated.
    Our generation should study diligently, explore new paths, and seek breakthroughs, hoping to expand the application of this material, so that it can bloom in various fields such as medicine and materials, and contribute to the development of chemistry.
    Toxicity Research
    In the chemical industry, there are things called 2, 4, 5 - Trifluorobenzenesulfonyl Chloride, which is crucial for toxicity research. This compound is strong in nature or contains potential danger. Yu Si probed in detail to observe its interaction with the surrounding things. Looking at its entry into various media, the changes that occur are recorded in detail. Examine its impact on all kinds of organisms, from insects to plants and trees, I dare not ignore it. Expect to know the mechanism of its toxicity and the depth of its harm. Hope to get the exact theory, for the future protection and use of regulations, to provide solid evidence, so that this chemical in the world, use it properly, and avoid disasters, to protect the safety of all things.
    Future Prospects
    Today there is a compound called 2,4,5 - Trifluorobenzenesulfonyl Chloride. Looking at this compound, it is unique in nature and has a wide range of uses. Although the current knowledge is limited, our generation of chemical researchers have high hopes for its future expansion.
    The structure of this substance is exquisite, and atoms such as fluorine, sulfur, and chlorine are cleverly connected, or it has special chemical activities. In the field of organic synthesis, it may be a powerful tool for constructing novel structures. Although the current relevant research is not mature, with time, with the deepening of exploration, more potential will be discovered.
    We firmly believe that in the future, we will be able to use the power of science and technology to clarify its reaction mechanism and expand its application scope. Or it can be used to create new drugs to overcome difficult diseases; or it can help material innovation and promote industrial progress. Its future is like a star, shining brightly, waiting for our generation to strive to pursue it, so as to uncover its mystery and contribute to the progress of chemistry and the well-being of mankind.
    Where to Buy 2,4,5-Trifluorobenzenesulfonyl Chloride in China?
    As a trusted 2,4,5-Trifluorobenzenesulfonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2,4,5-Trifluorobenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2,4,5-trifluorobenzenesulfonyl chloride?
    2% 2C4% 2C5-tribromobenzoate is an organometallic compound with special physical properties. Its appearance is mostly white powder, the texture is fine, it is stable at room temperature and pressure, and it is not easy to spontaneously react with common substances. This property makes it quite convenient for storage and transportation.
    Looking at its solubility, 2% 2C4% 2C5-tribromobenzoate is insoluble in water. Due to the large difference between the polarity of water molecules and the intermolecular forces of the compound, it is difficult for water molecules to overcome the internal forces of the compound to disperse and dissolve it. However, in some organic solvents, such as some polar organic solvents, it exhibits a certain solubility, and it can be dissolved and dispersed by forming specific interactions with organic solvent molecules.
    When it comes to melting point, 2% 2C4% 2C5-tribromobenzoate has a high melting point, and a higher temperature is required to transform it from solid to liquid. Due to the strong chemical bonds and intermolecular forces inside the compound, a lot of energy is required to break these forces, causing the relative motion between molecules to intensify, and then realizing the physical state transformation. The high melting point allows the compound to maintain a solid state in high temperature environments, with good thermal stability, which shows advantages in some application scenarios where high temperature resistant materials are required.
    2% 2C4% 2C5-tribromobenzoate zinc also has certain electrical insulation, because its internal electrons are bound around specific atoms or chemical bonds, and it is difficult for electrons to move freely under an external electric field to form an electric current. This property makes it suitable for applications in fields that require high electrical insulation.
    What are the chemical properties of 2,4,5-trifluorobenzenesulfonyl chloride?
    2% 2C4% methyl 2C5-tribromobenzoate is an organic compound with the following chemical properties:
    First, acidic. This molecule contains a carboxyl group, which can weakly ionize hydrogen ions in water and is acidic. In case of strong bases such as sodium hydroxide, a neutralization reaction will occur to form corresponding carboxylate and water, which is a typical property of organic acids.
    Second, substitution reaction. The hydrogen atom on the benzene ring is affected by the carboxyl group and the bromine atom, and has a certain activity. Under specific conditions, if the catalyst and the reaction temperature are suitable, an electrophilic substitution reaction can occur. For example, in the reaction with bromine elemental matter catalyzed by iron bromide, the unsubstituted position on the benzene ring will introduce bromine atoms to form polybrominated products.
    Hydrolysis of the tri-ester. The substance contains an ester group and can be hydrolyzed under the catalysis of acid or base. When acidic hydrolyzed, 2% 2C4% 2C5-tribromobenzoic acid and methanol are generated; when alkaline hydrolyzed, 2% 2C4% 2C5-tribromobenzoic acid and methanol are generated. The hydrolysis products vary depending on the reaction conditions.
    Fourth, halogenated hydrocarbon properties. The bromine atom in the molecule has the characteristics of halogenated hydrocarbons, and under the action of some nucleophiles, the bromine atom can be replaced. If it reacts with sodium alcohol, the bromine atom can be replaced by alkoxy groups to form corresponding ether compounds.
    Fifth, redox related. The benzene ring is relatively stable, but under the action of strong oxidants such as potassium permanganate, if the conditions are suitable, the side chain of the benzene ring may be oxidized; at the same time, some groups in the molecule can also undergo reduction reactions under the action of specific reducing agents, but the specific reaction depends on the reaction conditions and the reagents used.
    What are the main uses of 2,4,5-trifluorobenzenesulfonyl chloride?
    2%2C4%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF, its main uses are quite extensive. This substance can be used as an important raw material in the field of medicine. Because of its specific chemical properties, it can help synthesize many drug ingredients and make great contributions to the treatment and prevention of diseases. For example, some new drugs developed for specific diseases 2%2C4%2C5-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF as indispensable basic materials, or enhance drug efficacy, or optimize drug stability.
    In the chemical industry, 2%2C4%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF also plays a key role. It can be used to manufacture a variety of special chemicals, such as high-performance coatings, adhesives, etc. Take coatings as an example. After adding this substance, the corrosion resistance and wear resistance of coatings are significantly improved, thereby prolonging the service life. It is widely used in construction, industrial equipment protection, etc.
    In the field of materials science, 2%2C4%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF also plays an important role. With its unique chemical structure, it can improve the properties of materials and synthesize new high-performance materials. For example, in the manufacture of some high-tech electronic products, the use of special materials containing this substance can improve the conductivity, flexibility and other key performance indicators of the product, and meet the strict requirements of modern technology for materials.
    Furthermore, in the field of agriculture, although it is not directly used in crop cultivation, it can indirectly affect agricultural production by affecting the synthesis and performance of pesticides and fertilizers. Or improve the killing power of pesticides to pests, or enhance the nutrient release efficiency of chemical fertilizers, and help increase agricultural production and income. In short, 2%2C4%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF has important uses in many fields and contributes greatly to the development of various industries.
    What is the synthesis method of 2,4,5-trifluorobenzenesulfonyl chloride?
    To make 2,4,5-trifluorobenzoic anhydride, you can follow the following ancient method.
    First take an appropriate amount of 2,4,5-trifluorobenzoic acid and place it in a clean kettle. For the kettle, it should be made of pottery or copper, which can withstand high temperature and does not phase with the material. Under the kettle, slow down the burning with charcoal fire, so that the benzoic acid gradually melts and turns into a fluid.
    Then, add an appropriate amount of dehydrating agent, such as phosphorus pentoxide. For phosphorus pentoxide, it is dry and can be melted by water. Put it in the kettle, mix it with the liquid benzoic acid, and stir to make it well. The mixing equipment should be wood or bamboo, and do not use iron, lest the iron equipment and the material will be phased and mixed.
    When stirring, the fire is getting more and more fierce, causing the temperature in the kettle to rise gradually. Careful attention should be paid to the change of temperature, not too high or too low. If the temperature is too high, the material may decompose; if the temperature is too low, the reaction will be slow and difficult. When the flue gas in the kettle gradually rises, and there are bubbles gurgling out, this is the appearance of the reaction being in full swing.
    After a while, the reaction gradually finishes. When the material in the kettle is slightly cold, use a condenser to collect the steam escaping from it. The steam cools and condenses, that is, 2,4,5-trifluorobenzoic anhydride. The product received may be purified by recrystallization. Take an appropriate amount of solvent, such as ethanol or ether, dissolve the product into it, heat it to dissolve, and then cool it, so that the product slowly crystallizes and comes out, filtered to obtain pure 2,4,5-trifluorobenzoic anhydride.
    The whole process requires strict compliance with laws, paying attention to the heat, the amount of materials and the time of reaction, so as to obtain good results and obtain the required 2,4,5-trifluorobenzoic anhydride.
    What are the precautions for storing and transporting 2,4,5-trifluorobenzenesulfonyl chloride?
    2%2C4%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF%E5%9C%A8%E5%82%A8%E5%AD%98%E5%92%8C%E8%BF%90%E8%BE%93%E4%B8%AD%E5%BD%93%E4%B8%A5%E6%8C%81%E4%B8%8B%E5%88%97%E6%B3%A8%E6%84%8F%E4%BA%8B%E9%A1%B9:
    First, this substance is toxic and environmentally risky. When storing, it must be in a professional place and strictly abide by relevant regulations. It must not be placed at will. The warehouse should be cool, well ventilated, and away from fire and heat sources to avoid danger.
    Second, storage containers should be strictly selected to ensure that they are well sealed and prevent leakage. Commonly used metal or special plastic containers should be carefully inspected before use to check for damage or cracks.
    Third, the storage area should be marked with obvious warning signs, marked "toxic and harmful" "dangerous chemicals" and other words, so that personnel can clearly understand their danger. At the same time, they should be equipped with corresponding emergency treatment equipment and protective equipment, such as fire extinguishers, eye washers, gas masks, etc.
    Fourth, qualified professional transportation enterprises and personnel should be selected during transportation, and the transportation vehicles should be equipped with corresponding safety equipment and protective measures. Be stable during transportation to avoid damage to the container caused by bumps and vibrations. Drive according to the specified route and avoid densely populated areas and environmentally sensitive areas.
    Fifth, it will react with oxidants, acids, alkalis and other substances. Do not mix and transport during storage and transportation. Store and transport separately to prevent dangerous interactions.
    Sixth, storage and transportation personnel need to undergo professional training, familiar with the characteristics, hazards and emergency treatment methods of the substance, and strictly follow the operating procedures in daily operation.