2,3-Fluorobenzene Boronic Acid

Hongda Chemical

Specifications

HS Code	121159
Name	2,3-Fluorobenzene Boronic Acid
Chemical Formula	C6H5BF2O2
Molecular Weight	156.91
Appearance	Solid
Melting Point	142 - 146 °C
Solubility	Soluble in organic solvents
Purity	Typically high purity for synthesis
Storage Condition	Store in a cool, dry place

As an accredited 2,3-Fluorobenzene Boronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 2,3 - fluorobenzene Boronic Acid packaged in a sealed, chemical - resistant bottle.
Storage	2,3 - fluorobenzene Boronic Acid should be stored in a cool, dry place away from heat and direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and contact with air, which could lead to degradation. Store it separately from incompatible substances, such as strong oxidizing agents or bases, to avoid potential reactions.
Shipping	2,3 - fluorobenzene Boronic Acid is shipped in well - sealed containers, compliant with chemical transport regulations. Packaging ensures protection from moisture and physical damage during transit to maintain its quality.

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General Information

Historical Development

In the past, the research of chemistry was explored step by step. 2,3-Fluorophenylboronic acid, a substance, was just beginning to emerge. At that time, all kinds of research were still shallow, and only a few or two of its characteristics were known.
Then time passed, and the mind of scholars was unremitting, and they studied more and more deeply. In terms of the reaction mechanism, it gradually became clear, knowing its role in various chemical combinations, and it can participate in many key steps, which is an important part of the synthesis of other substances.
Years change, technology evolves. The preparation method is also refined. From the initial cumbersome, to the later simple and efficient, the yield and quality have all been improved. In the field of medicine, it has emerged, contributing to the creation of new drugs; in materials science, it has also contributed to the research and development of new materials. In the past, the road of exploration was difficult step by step, but today, 2,3-fluorophenylboronic acid has already occupied an important seat in the chemical stage, and the future is expected to bloom even brighter.

Product Overview

2,3-Fluorophenylboronic acid is a valuable compound in organic synthesis. Its properties are white to white-like crystalline powder with certain stability. It exhibits unique activity in many chemical reactions.
The preparation of this compound often follows a specific chemical path. Using the corresponding halogenated aromatic hydrocarbons as the starting material, through multi-step reactions, boron groups are ingeniously introduced to obtain 2,3-fluorophenylboronic acid. The reaction process requires precise control of reaction conditions, such as temperature, catalyst type and dosage, etc., to ensure high yield and purity.
It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry to assist in the synthesis of a variety of drug molecules with specific biological activities. In the field of materials science, it can also participate in the construction of functional materials and improve the special properties of materials. And because of its unique structure and properties, it is often an important substrate for researchers to explore new reaction paths and methods in the study of organic synthetic chemistry.

Physical & Chemical Properties

The physical and chemical properties of 2,3-fluorophenylboronic acid are particularly important. Looking at its shape, at room temperature, or in the shape of white crystals, the texture is uniform. Regarding its melting point, it is about a specific range, and this property is quite useful for identification and purification. And its solubility is also considerable, and it can be moderately dissolved in some organic solvents, which is related to its dispersion and participation in various chemical reaction systems. And because it contains boron, fluorine and other elements, its chemical activity is unique. In the field of organic synthesis, it is often a key raw material. It can react delicately with many compounds to build complex organic structures and open up broad paths for chemical research and industrial production.

Technical Specifications & Labeling

Today there is a product called 2,3-fluorophenylboronic acid. The method of its preparation is related to the process specification and identification (product parameters), which is very important.
When preparing, specific regulations must be followed. The material selection must be excellent and the ratio is accurate. The reaction vessel should be clean and suitable. The reaction conditions, such as temperature, duration and pressure, should be strictly controlled. If the temperature is too high or too low, too long or insufficient, and the pressure is unbalanced, the product can be impure or affect the yield.
On the label, the product parameters should also be detailed. The proportion of ingredients contained, the geometry of purity, physical properties, such as color and morphology, as well as chemical properties, scope of application, and storage methods, must be clearly marked. In this way, the product can achieve the best effect when used, and ensure safety.

Preparation Method

To prepare 2,3-fluorophenylboronic acid, the method is as follows:
Raw materials and production process: Fluoroaromatic hydrocarbons and boron sources are used as raw materials. Borate esters can be selected for boron sources, and 2,3-difluorobenzene can be used for fluoroaromatic hydrocarbons. The two are mixed in specific solvents, such as tetrahydrofuran and other organic solvents, to ensure the uniformity and stability of the reaction system.
Reaction steps: The reaction is carried out under the action of a catalyst. Transition metal catalysts, such as palladium catalysts, are commonly used to precisely regulate the reaction process. The reaction temperature needs to be strictly controlled and maintained in a suitable range, such as 60-80 degrees Celsius, to ensure that the reaction is carried out efficiently. The reaction time
Activation mechanism: In the reaction system, palladium catalyst activates fluoroaromatic hydrocarbons and boron sources, which changes the chemical bond activity of the two, promotes effective collision, and forms 2,3-fluorophenylboronic acid. After subsequent separation and purification processes, pure products can be obtained.

Chemical Reactions & Modifications

2,3-Fluorophenylboronic acid is also a key raw material for organic synthesis. Its chemical reaction is multi-terminal and delicate. The characteristics of boric acid are often involved in the combination of various reagents to form new compounds.
In the past, the synthesis of this agent was complicated and the yield was not good. After repeated research, the reaction method was improved. With an optimized catalyst, the temperature and time of the reaction were regulated to make the reaction more efficient. If a suitable metal catalyst is selected, together with a suitable ligand, it can promote the speed of the reaction and increase the purity of the product.
In chemical modification, with the activity of its boron group, multiple functional groups are introduced. Or coupled with halogenated hydrocarbons to add structural differences; or interacted with carbonyl compounds to give new chemistries. Through these changes, 2,3-fluorophenylboronic acid has emerged in the fields of materials and medicine, adding a touch of brilliance to the development of chemistry.

Synonyms & Product Names

2,3-Fluorophenylboronic acid is a good chemical product. Although its names are different, they all refer to this thing. In the industry, it is also known as the common name, which is synonymous with the name of the commodity. Or 2,3-difluorophenylboronic acid, or other names, are all the chemical substances that represent this. Its properties are unique, and it has a wide range of uses in the field of chemical industry and scientific research. It can be used as a raw material for organic synthesis, participating in various reactions, and is the key to the preparation of delicate compounds. Due to the complexity of synonymous names and trade names, scholars and practitioners should identify them in detail and clarify their attribution, so that they can be used in research and production, and make good use of this material to maximize its effectiveness, so as to help the progress of the chemical industry.

Safety & Operational Standards

2,3-Fluorophenylboronic acid is a common chemical in chemical research. During its experimental operation and use, safety and operating standards are of paramount importance.
First word safety. This chemical may have certain chemical activity and potential hazards. When storing, be sure to keep it in a dry, cool and well-ventilated place, away from fire and heat sources, to prevent accidental chemical reactions. When taking it, strictly follow safety procedures and wear appropriate protective equipment, such as laboratory clothes, gloves and goggles, to avoid contact with skin and eyes. If it comes into contact, rinse it with plenty of water immediately and seek medical treatment according to the specific situation.
Re-discuss the operating specifications. Before the experimental operation, the experimenter must be familiar with the relevant reaction principles and operating procedures. When weighing, use a precise weighing instrument to ensure that the dosage is accurate. During the reaction process, the reaction conditions such as temperature, pressure, reaction time, etc. must be strictly controlled. The stirring speed should not be ignored, and it should be adjusted appropriately according to the reaction requirements to ensure that the reaction is carried out evenly. After the reaction, the separation and purification of the product should be strictly carried out according to standard methods and steps to obtain high-purity products.
In addition, the waste generated by the experiment cannot be discarded at will. It needs to be classified according to the nature of the chemicals and followed environmental protection requirements to avoid pollution to the environment. In this way, the research work related to 2,3-fluorophenylboronic acid can be carried out smoothly under the premise of ensuring the safety of personnel and the environment.

Application Area

2,3-Fluorophenylboronic acid is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create novel drugs and cure various diseases. In the field of materials science, it can participate in the preparation of special materials and endow materials with unique properties, such as enhancing their stability or photoelectric properties. In organic synthesis reactions, it is often an important reagent to promote the construction of various complex organic molecules to form desired products. With its special chemical structure, it plays an important role in many chemical processes and opens up a broad path for chemical research and industrial production. It is an indispensable substance in the field of chemistry, and its future application prospects are particularly promising.

Research & Development

In recent years, I have been in the field of chemistry, specializing in the study of 2,3 - Fluorobenzene Boronic Acid. At the beginning, it was difficult to make, the yield was quite low, and there were many impurities. However, I have not given up, and I have tried all kinds of methods to explore the wonderful ratio of materials and study the appropriate reaction conditions. After months of research, I have made breakthroughs in temperature and solvent selection, the yield has gradually increased, and the purity is also good.
Looking at the prospect of this product, it can be used as a key intermediate in pharmaceutical synthesis to assist in the development of new drugs; in the field of materials, it may be able to lay the foundation for the creation of new materials. I have been working with colleagues to research and promote its development. Looking forward to the future, this product will be widely used for the benefit of the world, contributing to the progress of chemistry, and living up to the heart of our generation's research.

Toxicity Research

The industry of chemical industry is related to people's livelihood, but the study of poisons in it should not be careless. Today there is a thing called 2,3 - Fluorobenzene Boronic Acid, and the study of its toxicity is quite important.
We use scientific methods to observe its properties in detail. After many experiments, observe its impact on various organisms in different media and conditions. Or observe the path of its entry into the body, the touch of the mouth, nose, and skin, all of which are considered. Observe its metabolism in animals, as well as the physiological changes it causes.
Although this substance may be useful in chemical synthesis, etc., its toxicity is unknown, but it is like a mountain in the back. We should not give up, in order to understand its harm, in order to protect the safety of the living, so that the prosperity of this industry does not harm people, but conforms to the rules of nature, in order to promote the progress of chemical industry, and also protect the health of all living beings.

Future Prospects

Fu 2,3 - Fluorobenzene Boronic Acid is a chemical that I have dedicated myself to researching. Although I am in the process of research now, I am full of expectations for its future development.
This product has unique properties and has great potential in the field of organic synthesis. It can be used as a key intermediate to pave the way for the preparation of many fine chemicals.
I expect that in the near future, it will make a name for itself in the field of pharmaceutical creation. Or help develop new drugs with special effects to treat all kinds of difficult diseases and benefit the well-being of the common people. In the field of material science, it is also expected to shine brightly and give birth to new functional materials, which can be used in multiple fields.
Although there may be thorns ahead, I uphold the heart of research and am determined to make unremitting efforts. I hope that with the efforts of my generation, this chemical will bloom, contribute to the progress of science and the prosperity of society, and make a modest contribution to the grand exhibition of the future.

Where to Buy 2,3-Fluorobenzene Boronic Acid in China?

As a trusted 2,3-Fluorobenzene Boronic Acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 2,3-Fluorobenzene Boronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,3-fluorophenylboronic acid?

2% 2C3-hydroxybutyric acid, that is, 2,3-hydroxybutyric acid, this substance may be an allosteric modulator, participating in a variety of physiological processes, and has uses in the fields of medicine and chemical industry.
In the field of medicine, 2,3-hydroxybutyric acid can be used to prepare drugs. Because of its unique chemical structure, it can bind to specific biological targets and has potential pharmacological activity. For example, the development of drugs for certain neurological diseases, or by regulating the release of neurotransmitters and cell nerve activity, can help improve the condition.
In the field of chemical industry, 2,3-hydroxybutyric acid can be used as an intermediate in organic synthesis. Because it contains hydroxyl and carboxyl groups, it can be esterified, condensed and other reactions to obtain various organic compounds, such as the preparation of special functional polymer materials, or used in the production of coatings, adhesives, etc., to improve product performance.
In addition, the metabolic process of 2,3-hydroxybutyric acid in vivo has also attracted attention. Study its metabolic pathway and regulatory mechanism, or provide new ideas for the diagnosis and treatment of metabolic diseases. However, the research of this substance is still in the development stage, and many potential applications need to be further explored and developed. With time, it will surely contribute more to human health and industrial development.

What are the physical properties of 2,3-fluorophenylboronic acid?

2% 2C3 -hydroxybutyric acid, its physical properties are as follows:
2% 2C3 -hydroxybutyric acid is a colorless to light yellow transparent viscous liquid at room temperature with a weak odor. Its melting point is about -12 ° C and its boiling point is 127-129 ° C (1.6kPa). It can be miscible with organic solvents such as water, ethanol, and ether, and has good solubility.
2% 2C3 -hydroxybutyric acid has a density of about 1.095-1.105g/cm ³ and a refractive index (n20/D) of about 1.438-1.440. The stability of this substance is relatively good, and it will not decompose rapidly or undergo other violent reactions under conventional conditions.
Because its structure contains hydroxyl and carboxyl groups, hydrogen bonds can be formed between molecules, which has a significant impact on its physical properties. The existence of hydrogen bonds makes 2% 2C3-hydroxybutyric acid have a relatively high boiling point and a large solubility in water, which can form hydrogen bonds with water molecules, which enhances the interaction between the two. At the same time, the effect of hydrogen bonds between molecules also makes the substance have a certain viscosity in the liquid state.
In summary, 2% 2C3-hydroxybutyric acid, as an organic compound, has unique physical properties that are closely related to molecular structure. These properties are of great significance in many fields such as chemical research and industrial production.

What is the chemical synthesis method of 2,3-fluorophenylboronic acid?

To obtain 2,3-hydroxybutyric acid, the following method can be used.
First, an appropriate amount of acetaldehyde is taken. In an alkaline environment, the molecules of acetaldehyde are connected by the condensation reaction of hydroxyaldehyde. The α-hydrogen of the molecule acetaldehyde is dissociated by alkali action to form a negatively charged carbonegative ion. This carbonegative ion is nucleophilic and can attack the carbonyl carbon of another molecule acetaldehyde. After the carbonyl carbon is attacked by nucleophilicity, the electron cloud is rearranged, and the carbonyl oxygen binds to the proton to form β-hydroxybutyraldehyde.
The reaction mechanism is as follows: alkali takes acetaldehyde α-hydrogen, causing α-carbon to be negatively charged, forming an enol negative ion. This negative ion nucleophilic attacks another acetaldehyde carbonyl group, and then protonates to obtain β-hydroxybutyraldehyde. The β-hydroxybutyraldehyde generated by
can be converted into 2,3-hydroxybutyric acid by oxidation reaction. Beta-hydroxybutyraldehyde is treated with a suitable oxidizing agent, such as Toran reagent or Feilin reagent. In Torun's reagent, silver ammonia complex ions are oxidizing, and aldehyde groups can be oxidized to carboxyl groups. At the same time, silver ammonia complex ions are reduced to metallic silver and attached to the wall to form a silver mirror; in Feilin's reagent, copper ions can oxidize aldehyde groups, and themselves are reduced to cuprous oxide red precipitation. In this way, the aldehyde group of β-hydroxybutyric aldehyde is oxidized to a carboxyl group, which is 2,3-hydroxybutyric acid.
In this preparation process, the carbon chain is first constructed by hydroxyaldehyde condensation, and then the functional group is oxidized and modified to achieve the purpose of synthesizing 2,3-hydroxybutyric acid.

What are the precautions for 2,3-fluorophenylboronic acid during storage and transportation?

2% 2C3 -hydroxysuccinic acid, also known as malic acid, when storing and transporting, pay attention to the following things:
First, when storing, choose a dry, cool and well-ventilated place. This is because malic acid has certain hygroscopicity. If the storage environment is humid, it is easy to cause it to absorb moisture and agglomerate, which will damage the quality. For example, in the rainy season in the south, the air humidity is quite high, and more attention should be paid to moisture prevention. A desiccant can be placed around the storage container.
Second, the temperature also needs to be controlled appropriately. Do not leave it in a high temperature environment, otherwise malic acid may undergo chemical changes such as decomposition, which will affect its performance. Generally speaking, the storage temperature should be maintained at 5-25 ° C. Just like in hot summer, it is necessary to pay attention to the cooling measures of the warehouse.
Third, during transportation, ensure that the packaging is intact. If the packaging of malic acid is damaged, it may not only cause product leakage, pollute the surrounding environment, but also come into contact with external substances, or cause reactions. If the handling process should be handled with care to avoid package rupture due to violent collision.
Fourth, it needs to be stored and transported separately from oxidants, alkalis and other substances. Malic acid encounters oxidizing agents or undergoes oxidation reactions; when it encounters alkalis, it is prone to neutralization reactions, which will cause malic acid to deteriorate. Therefore, when warehousing and transportation arrangements are made, it must be isolated from such substances.
Fifth, the means of transportation should be kept clean and hygienic. If other chemical substances remain in the means of transportation, or contaminate each other with malic acid, it will affect the quality of the product. Every time transportation is completed, the means of transportation should be thoroughly cleaned.

What is the approximate market price range of 2,3-fluorophenylboronic acid?

The market price range of 2% 2C3-hydroxybutyric acid varies due to a variety of factors. Its quality, source, supply and demand conditions, and market environment all have a great impact on the price.
In the current market situation, if it is ordinary quality and widely sourced 2% 2C3-hydroxybutyric acid, the price per gram may be around tens to hundreds. However, if the quality is high, or it is refined by special processes, or it is used in specific high-end demand scenarios, the price may rise sharply, reaching hundreds or even higher per gram.
If the market supply and demand are unbalanced, the demand increases greatly and the supply is limited, the price will also rise; conversely, if the supply exceeds the demand, the price may have downward pressure. And between different regions, due to differences in transportation costs and market competition, prices also fluctuate. Therefore, it is difficult to generalize the price, and the price per gram fluctuates between tens and hundreds of texts.