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2,3-Difluoronitrobenzene

2,3-Difluoronitrobenzene

Hongda Chemical

Specifications

HS Code

536396

Chemical Formula C6H3F2NO2
Molecular Weight 159.09
Appearance Colorless to light yellow liquid
Boiling Point 205 - 207 °C
Melting Point 12 - 14 °C
Density 1.446 g/cm³ (at 20 °C)
Vapor Pressure Low
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 86 °C
Refractive Index 1.524 (at 20 °C)

As an accredited 2,3-Difluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250 - gram bottle of 2,3 - difluoronitrobenzene with secure chemical - resistant packaging.
Storage 2,3 - difluoronitrobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly sealed container to prevent leakage and vapor escape. Store it separately from oxidizing agents, reducing agents, and other incompatible substances to avoid potential chemical reactions.
Shipping 2,3 - difluoronitrobenzene is shipped in tightly - sealed containers, usually drums or bottles, compliant with hazardous chemical regulations. It's transported by specialized carriers ensuring proper handling to prevent spills and ensure safety during transit.
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2,3-Difluoronitrobenzene 2,3-Difluoronitrobenzene
General Information
Historical Development
2,3-Difluoronitrobenzene is an important raw material for organic synthesis. Its development traces can be traced back to the past. In the early years, organic chemistry flourished, and many wise men studied the properties and changes of substances. At that time, it was difficult to explore the synthesis of fluorinated compounds.
However, the advanced chemists persevered, and after countless trials and errors, they finally got the method of synthesizing 2,3-difluoronitrobenzene. At first, the process was difficult and the yield was low. However, with the passage of time, science and technology advanced, and new catalysts and new reaction conditions continued to emerge. The road to synthesis has gradually become smooth, and the yield has also increased significantly. This compound has emerged in the fields of medicine, pesticides, etc., providing a key foundation for various creations. Its development process is a brilliant chapter in chemical exploration.
Product Overview
2,3-Difluoronitrobenzene is a key material for organic synthesis. It is a colorless to light yellow liquid with a special odor. The molecular structure of this compound is exquisite, containing difluorine atoms and nitro groups, giving it unique chemical activity.
In the field of chemical industry, it has a wide range of uses. It is often an important intermediate for the preparation of many fine chemicals. Through specific chemical reactions, it can be converted into various high value-added products. In the process of drug synthesis, it also plays a key role, helping to build special chemical structures and laying the foundation for the creation of new drugs.
Preparation method, through clever chemical pathways. Using specific aromatic hydrocarbons as starting materials, it is carefully synthesized through a series of steps such as halogenation and nitrification. However, the preparation process requires careful control of reaction conditions, such as temperature, pressure, and catalyst dosage, to ensure the purity and yield of the product.
Physical & Chemical Properties
2,3-Difluoronitrobenzene is also a chemical product. It has unique physical and chemical properties. Looking at its shape, it is often a colorless to light yellow liquid with a unique taste. Regarding its melting and boiling, the melting point is quite low, and it is in a flowing state in ordinary environments. The boiling point is moderate, and it is vaporized to reach a specific temperature. Its density is greater than that of water, and it is placed in water and sinks to the bottom.
In terms of solubility, it is easily soluble in organic solvents such as ethanol and ether, but insoluble in water. This is due to its structure. Its chemical activity, fluorine and nitro groups are both active groups, and it is easy to cause reactions. Nitro is rich in electrosorption, which makes the electron cloud of benzene ring dense and easy to be replaced by electrophilicity. Although fluorine atoms are small and have strong electronegativity, they also affect the reactivity. Therefore, they are the key materials in organic synthesis and have a wide range of uses.
Technical Specifications & Labeling
Nowadays, there is a research and development of chemical products, which concerns 2,3-difluoronitrobenzene. Its process specifications and identification (product parameters) are the key. To make this product, precise process regulations must be followed. The selection of raw materials must be excellent, and the ratio must be accurate. Reaction conditions such as temperature and pressure must be strictly controlled to obtain the ideal product.
As for the identification (product parameters), its chemical properties, purity geometry, physical properties, etc. should be detailed. The purity of this product should meet specific standards, and the impurity content must be strictly limited. Physical properties such as color, odor, melting point, boiling point, etc., should be clearly marked. In this way, the chemical can be used to provide users with accurate evidence to ensure its safe and effective use.
Preparation Method
The method of making 2,3-difluoronitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism, which is the key to chemical preparation.
To make this product, the material selection is necessary. The commonly used raw materials are substances with a specific chemical structure. Only by ingenious compatibility can they lay the foundation for the reaction. The production process requires precise control of the conditions. Changes in temperature and pressure are all related to the reaction trend and the purity of the product.
The reaction steps are ordered in sequence. First, the raw materials are mixed in a specific order to initiate the reaction under a suitable environment. In this case, it may be necessary to heat to increase molecular activity, or to control the temperature to prevent side reactions. And the catalytic mechanism is indispensable. Selecting a suitable catalyst can speed up the reaction process, reduce the activation energy, and improve the yield.
After these steps and rigorous operation, pure 2,3-difluoronitrobenzene can be obtained, which is a good product for the chemical industry to meet the needs of all parties.
Chemical Reactions & Modifications
Nowadays, there are 2,3-difluoronitrobenzene. In the field of organic synthesis, its chemical reaction and modification are quite important to our chemical researchers.
To study its reaction, it often involves nucleophilic substitution. Because of the fluorine atom on the benzene ring, affected by the nitro group, the activity is greatly increased. Nucleophilic reagents approach, and fluorine atoms are easily replaced to form different derivatives. This is a commonly used method in organic synthesis.
As for modification, it can be chemically modified to adjust its physical and chemical properties. Or introduce functional groups to change its reactivity and solubility. In this way, 2,3-difluoronitrobenzene can be used in the fields of medicine, pesticide creation, etc., to develop its application. After rational design of reaction paths and precise modification, compounds with specific properties can be obtained, which can contribute to chemical research and industrial development.
Synonyms & Product Names
For 2,3-difluoronitrobenzene, it is also a chemical substance. Its name has a synonym with the name of the commodity, which can be seen in the field of chemical industry. Synonymous names, or exist due to differences in researchers, places of origin, habits, etc. The name of the commodity is mostly determined by the manufacturer, hoping to show its characteristics and facilitate its sale.
Looking at the past, the names of chemical substances are often different due to time changes and places. 2,3-difluoronitrobenzene, its synonymous name, or used in the past, and later gradually changed to a new name; or in a specific place or a specific industry, it still exists. As for the name of the commodity, the manufacturer gives it a special name according to its nature and use, which is different from other things.
In today's world, the chemical industry is advancing day by day, and the use of 2,3-difluoronitrobenzene is becoming more and more widespread. To clarify its synonymous name and the name of the commodity, researchers can read ancient and modern literature to avoid confusion; to the industry, to facilitate its trade and communication. Therefore, it is important to identify its name, and it is also related to the research, production and sales of the chemical industry.
Safety & Operational Standards
Specifications for the safety and operation of 2,3-difluoronitrobenzene
For those with 2,3-difluoronitrobenzene, it is also an essential chemical product. Its nature is different, and it is related to safety and operation standards. Don't be careless.
The way to safety, the first storage. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources, to prevent it from being heated and changed. It is also necessary to keep away from oxidizing agents, reducing agents and other substances to avoid the risk of reaction. Where it is stored, prepare fire extinguishing equipment, such as dry powder, carbon dioxide fire extinguishers, etc., for emergencies.
When operating, follow the regulations. The operator must wear protective clothing, protective gloves and goggles to protect the body and skin from damage. Do it in the ventilation cabinet to disperse the volatile gas in time and prevent it from entering the path of breathing. When weighing, the appliance is precise and the action is steady, and the medicinal materials should not be spilled. If there is any spill, cover it with sand, vermiculite and other materials immediately and collect it, and then dispose of it properly.
Preparation process, strictly abide by the procedures. Appropriate temperature control and pressure control, and feed the materials in sequence, must not be out of order. Close observation of the reaction, if there is any abnormality, stop it immediately, investigate the reason, and then draw a picture.
There are also regulations for disposal. It should not be disposed of at will. When it is in accordance with the principles of environmental protection, it should be collected by classification and handed over to professional institutions to meet the ecological balance.
In general, the safety and operating standards of 2,3-difluoronitrobenzene should be kept in mind and implemented in reality, so as to ensure that everything goes smoothly and avoid disasters.
Application Area
2,3-Difluoronitrobenzene is an important chemical product. Its application field is quite extensive. In the field of pharmaceutical synthesis, it is often a key intermediate, helping to form a variety of special drugs, healing various diseases, and saving people from pain. In the creation of pesticides, it is also indispensable. It can produce high-efficiency pesticides, protect crops, and ensure the hope of a bumper harvest. And in the field of material science, it participates in the synthesis of special materials, or has unique photoelectric properties. It is used in high-tech products, adding to the progress of science and technology. From this point of view, 2,3-difluoronitrobenzene has significant contributions in many practical fields, promoting the prosperity of various industries.
Research & Development
In recent years, I have dedicated myself to the research of 2,3-difluoronitrobenzene. This compound has unique properties and has great potential in various fields of chemical industry.
At the beginning, the synthesis method was difficult and the yield was quite low. However, we were not discouraged. We dedicated ourselves to studying ancient books, learned from the wisdom of predecessors, and improved the process through repeated experiments. With new catalysts, we optimized the reaction conditions and finally increased the yield.
Looking at its application, it can be used as a key intermediate in pharmaceutical synthesis to assist in the development of new drugs; in materials science, it can endow materials with special properties. We also look to the future, hope to expand its application scope, and work with colleagues to promote the development of this product, adding bricks and mortar to the chemical industry and benefiting more fields.
Toxicity Research
Study on Toxicity of 2,3-Difluoronitrobenzene
The use of 2,3-difluoronitrobenzene is also a chemical product. In today's world, the chemical industry is prosperous, and the use of such compounds is becoming more and more widespread. However, the investigation of its toxicity cannot be ignored.
Looking at its physical properties, 2,3-difluoronitrobenzene has special properties. After various experiments, it can be known that it can be poisoned into the body of living things, either by breathing or through the skin. In animal experiments, if the mice exposed to this substance were initially restless, then sluggish, and their diet gradually decreased. And its liver and kidney functions were also affected. The biochemical indicators of the test showed that liver enzymes were increased, and kidney detoxification function was also hindered.
Looking at its harm to cells, in vitro cell experiments, it can cause cell morphology changes, proliferation inhibition, and apoptosis. Push its toxicology, or because of the fluorine and nitro groups in the structure, it is easy to react with various molecules in the cell, disturbing its metabolic order and impairing its normal ability. Therefore, when using 2,3-difluoronitrobenzene, protective measures must be taken to ensure the safety of people and things.
Future Prospects
2,3-Difluoronitrobenzene, this chemical substance, in the eyes of our chemical researchers, holds great promise for future expansion. Looking at its structure, it is a unique genus of fluorine and nitro, endowing it with extraordinary chemical activity.
In the future, one of them may emerge in the field of drug synthesis. With its activity, special new drugs can be made, which will contribute to the treatment of diseases. Second, material science also has potential. With its participation, or the creation of new materials with outstanding performance, it can be applied to electronics and aerospace.
We should study it diligently and explore its potential, hoping to attract it to the vast world, bloom the brilliance of the future, and contribute to the progress of science and the prosperity of mankind.
Where to Buy 2,3-Difluoronitrobenzene in China?
As a trusted 2,3-Difluoronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,3-Difluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,3-difluoronitrobenzene?
2% 2C3 -diacetylamino naphthalene, its main uses are as follows:
This substance has a wide range of uses in the field of dyes. Due to its unique structure, the cap can be used as an important dye intermediate. Through a series of chemical reactions, it can be converted into a variety of bright colors and excellent fastness dyes, which can be used in the dyeing process of fabrics, leather and other materials to make the dyes colorful and long-lasting.
In the field of pharmaceutical synthesis, 2% 2C3 -diacetylamino naphthalene also plays a key role. With its special chemical activity, it can be used as a starting material or key intermediate for the synthesis of certain drugs. With the help of organic synthesis methods, it can be cleverly combined with other compounds to construct drug molecules with specific pharmacological activities, contributing an important force to the research and development of
Furthermore, in the field of organic synthetic chemistry, as an important basic raw material, it is often involved in the construction of various complex organic compounds. Chemists use its unique functional group characteristics to synthesize organic molecules with special structures and properties through carefully designed reaction paths, providing basic support for the development of materials science, fine chemistry and many other fields. For example, in the creation of new functional materials, 2% 2C3-diacetamidine naphthalene may be used as a core structural unit to endow materials with unique optical, electrical or mechanical properties.
What are the synthesis methods of 2,3-difluoronitrobenzene?
2% 2C3-diethylaminobenzaldehyde is a key intermediate in organic synthesis, and there are many synthesis methods. Although its synthesis is not accurately recorded in Tiangong Kaiwu, the following synthesis methods can be deduced by using the ideas of ancient chemical processes and the knowledge of modern organic synthesis:
First, benzaldehyde is used as the starting material and can be obtained by condensation reaction with diethylamine. This reaction may need to be carried out smoothly under the conditions of the existence of a specific catalyst. In ancient times, although there were no catalysts as precise as today, the catalytic activity of certain natural substances, such as certain minerals or specific plant extracts, could be used. At a suitable temperature and reaction time, benzaldehyde interacts with diethylamine to gradually generate 2% 2C3-diethylaminobenzaldehyde.
Second, the benzene ring can be modified first. First, benzene undergoes a substitution reaction, a suitable substituent is introduced, and then through a series of transformations, the substituent is gradually converted into diethylamino and aldehyde groups. For example, a halogen atom is introduced at a specific position in the benzene ring by a halogenation reaction, and then a nucleophilic substitution reaction replaces the halogen atom with a diethylamine group, and then a specific oxidation reaction is carried out to generate an aldehyde group at a suitable position. In ancient chemical processes, although the halogenation reaction conditions were difficult to precisely control, the halogenation process could be slowly realized with the help of some halogenated substances in the natural environment.
Third, it can also start from other compounds containing benzene rings. If there are natural products with similar structures, their structures can be modified by hydrolysis, oxidation, reduction and many other reaction steps. In ancient times, the utilization of natural products is rich in experience, or the starting materials can be found from some plants and minerals, and 2% 2C3-diethylaminobenzaldehyde can be obtained through multiple steps.
Synthesis of 2% 2C3-diethylaminobenzaldehyde has various methods. Although the ancient chemical process is rather simple compared with modern times, it may be possible to explore a feasible synthesis method with the wisdom and experience of the ancients.
What are the physical properties of 2,3-difluoronitrobenzene?
2% 2C3-diethylaminobenzene, its physical properties are as follows:
This substance is mostly colorless to light yellow liquid at room temperature, with a special odor. Its odor is unique, similar to the odor of some organic amines. It can be slightly emitted in the air, and is easily detectable by people with a keen sense of smell.
The boiling point is about 216-217 ° C. At this temperature, the substance converts from liquid to gaseous state. Due to the sufficient energy obtained by the molecule, it can overcome the intermolecular force to escape the liquid surface. This boiling point characteristic makes it have specific applications in chemical operations such as distillation and separation. 2% 2C3-diethylaminobenzene can be separated from the mixture according to the difference in boiling point.
The melting point is around -40 ° C. When the temperature drops below the melting point, the substance solidifies from a liquid state to a solid state, and the molecular arrangement changes from a disordered liquid state to an ordered solid lattice structure.
The relative density is about 0.936 (20 ° C). It means that at 20 ° C, the ratio of the density of the substance to the density of water at 4 ° C is 0.936, which indicates that its density is less than that of water. If mixed with water, it will float on the water surface.
In terms of solubility, it is slightly soluble in water, but it can be miscible with organic solvents such as ethanol and ether. Because the molecular structure of the substance contains hydrophobic hydrocarbon groups and hydrophilic amino groups, but the overall hydrophobic effect is dominant, it is difficult to dissolve in water; and it can be uniformly mixed and dissolved with organic solvents through the principle of similar miscibility, relying on the interaction between molecules such as
What are the precautions for storing and transporting 2,3-difluoronitrobenzene?
2% 2C3-diethoxybenzaldehyde is an organic compound. During storage and transportation, there are indeed many key precautions that need to be treated with caution:
First, when storing, it is advisable to choose a cool and ventilated warehouse. This is because it is volatile, high temperature or volatile, and may cause chemical reactions due to excessive temperature. The warehouse should be kept away from fire and heat sources to avoid fire hazards. Because it is exposed to open flames, hot topics, or the risk of combustion and explosion.
Second, it should be stored separately from oxidants, acids, alkalis, etc., and should not be stored mixed. Due to the chemical properties of 2% 2C3-diethoxybenzaldehyde, contact with oxidants or cause severe oxidation reactions; contact with acids and bases, or cause chemical reactions, change its chemical structure and properties, affect quality, and even cause danger.
Third, the storage area should be equipped with suitable materials to contain leaks. In case of leakage, it can be dealt with in a timely and effective manner to avoid polluting the environment and causing other hazards.
Fourth, during transportation, it is necessary to ensure that the container does not leak, collapse, fall, or damage. Because it is in the form of liquid or solid, it is easy to leak if the packaging is damaged. The tank (tank) used during transportation should have a grounding chain, and holes can be set in the tank to baffle to reduce shock and generate static electricity.
Fifth, it is strictly forbidden to mix and transport with oxidants, acids, alkalis, etc. This is the same as the storage requirements to prevent dangerous reactions caused by mutual contact during transportation.
Sixth, during transportation should be protected from exposure to the sun, rain, and high temperature. Sun exposure and high temperature, or make substances volatilize and decompose, may also increase the pressure in the packaging container, causing the container to break. After transportation, the vehicle should be thoroughly cleaned to eliminate residual substances and avoid affecting the subsequent transportation items.
What are the effects of 2,3-difluoronitrobenzene on the environment and the human body?
2% 2C3 -diacetylamino naphthalene, this substance has a significant impact on the environment and human body.
In the environment, if it is released into nature, it may cause many consequences. The first to bear the brunt, it can be toxic to aquatic organisms. Due to its special chemical structure, once it enters the water body, it may interfere with the physiological process of aquatic organisms, causing their growth and reproduction to be blocked. Or damage their nervous system and endocrine system, reduce the population, and destroy the balance of water ecology.
In soil, if it remains in the soil, or changes the physical and chemical properties of the soil, it will affect the activity and community structure of soil microorganisms. It further affects the absorption of nutrients by plant roots, hinders plant growth and development, and even causes plant diseases and death, destroying the stability of terrestrial ecosystems.
For the human body, it is risky to ingest through respiratory tract, skin contact or accidental ingestion. It may be a potential carcinogen. Long-term exposure may induce cancer and endanger life and health. It may also interfere with the metabolism of the human body, causing damage to important organs such as the liver and kidneys. The liver is responsible for detoxification. If it is affected by it, the detoxification function may be damaged, and the toxins in the body cannot be excreted in time; the kidneys are related to excretion. If it is damaged, the excretion of waste and excess water in the body will be delayed, causing a series of symptoms such as body edema.
In summary, 2% 2C3-diacetylamino naphthalene is potentially harmful to the environment and human body. During its production, use and treatment, it should be treated with caution, and supervision and prevention should be strengthened to reduce its threat to the ecological environment and human health.