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2,3-Difluorobromobenzene

2,3-Difluorobromobenzene

Hongda Chemical

Specifications

HS Code

806444

Chemical Formula C6H3BrF2
Molar Mass 207.009 g/mol
Appearance Liquid
Density 1.72 g/cm³
Boiling Point 162 - 164 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 62 °C
Odor Characteristic aromatic odor
Stability Stable under normal conditions

As an accredited 2,3-Difluorobromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram bottle packaging for 2,3 - difluorobromobenzene chemical.
Storage 2,3 - difluorobromobenzene should be stored in a cool, well - ventilated area away from heat and ignition sources. Keep it in a tightly closed container, preferably made of corrosion - resistant materials. Since it may be toxic and flammable, store it separately from oxidizing agents, acids, and bases to prevent chemical reactions and potential hazards.
Shipping 2,3 - difluorobromobenzene is shipped in tightly - sealed, corrosion - resistant containers. Shipment adheres to strict chemical transportation regulations, ensuring proper handling to prevent leakage and maintain safety during transit.
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2,3-Difluorobromobenzene 2,3-Difluorobromobenzene
General Information
Historical Development
Wenfu 2,3-difluorobromobenzene, its birth and development, is a chapter in the evolution of chemistry. In the past, the chemical sages, exhaustive research efforts, in the field of organic synthesis, up and down the search.
At the beginning, exploring the method of synthesis, thorns are full of thorns. The dukes studied day and night, trying various reagents and techniques, hoping to obtain a wonderful method for making this thing. Despite repeated setbacks, he was as determined as a rock, and refused to give it up lightly.
After several years of cold and heat, he finally got something. Clever preparation of reactants, precise control of the temperature, pressure and time of the reaction, so that 2,3-difluorobromobenzene can gradually be synthesized stably. From then on, in the forest of organic synthesis, it has a place to play, paving the foundation for subsequent chemical research and industrial applications, opening a new chapter, and adding a touch of brilliance to the long river of chemical development.
Product Overview
Description of 2,3-difluorobromobenzene
There is currently a product called 2,3-difluorobromobenzene. It is an organic halide with a unique structure. On the benzene ring, fluorine and bromine atoms are arranged in an orderly manner, giving this product its unique properties.
Looking at its physical characteristics, at room temperature, it is mostly colorless to light yellow liquid, with a clear texture and a special odor. Its boiling point, melting point, etc. vary depending on the interaction of atoms in the molecule.
When it comes to chemical properties, due to the strong electronegativity of fluorine and bromine atoms, the distribution of electron clouds in the benzene ring changes, resulting in different activities. In many reactions, such as nucleophilic substitution and electrophilic substitution, it shows a unique reaction path.
This product is widely used in the field of organic synthesis. It is often a key intermediate, used to prepare various fluorine and bromine-containing fine chemicals, such as medicine, pesticides, materials and other fields. The products derived from it may have antibacterial and insecticidal effects, or have special optical and electrical properties, and play an important role in industrial production and scientific research.
Physical & Chemical Properties
2,3-Difluorobromobenzene is also an organic compound. Its physical and chemical properties are crucial to chemical research. Looking at its physical properties, at room temperature, or as a colorless liquid, it has a special odor. Its boiling point, melting point, etc., are all characteristics. The number of boiling points depends on the intermolecular forces. The presence of fluorine and bromine atoms in this compound makes the intermolecular forces unusual.
On its chemical properties, due to the different electronegativity of fluorine and bromine, the electron cloud density distribution of the benzene ring changes. Therefore, in the electrophilic substitution reaction, its activity is different from that of benzene. The positioning effect of fluorine and bromine atoms is the check point of the reaction. In the process of organic synthesis, this substance can be a key intermediate. Through specific reactions, a variety of compounds can be derived, which have potential uses in the fields of medicine and materials.
Technical Specifications & Labeling
Today there is a product called 2,3-difluorobromobenzene. To clarify its technical specifications and labels (commodity parameters), you should consider it in detail.
To make this product, the purity of the first raw material. The proportions of various ingredients must be accurate, such as fluoride, bromide, etc., prepared according to the recipe, and there must be no difference. The temperature and pressure of the reaction are also critical. If the temperature is high, it will be rapid and variable in quality, and if the temperature is low, it will be difficult to achieve. It must be controlled to an appropriate degree to obtain the best effect.
Its logo should also specify the ingredients, properties, uses, etc. The proportion of 2,3-difluorobromobenzene should be specified, and its color, taste and state should be described. Uses are shown in what fields can be used, such as medicine, chemical synthesis. In this way, the technical specifications and labels are clear, and there is no confusion for those who use this product.
Preparation Method
If you want to make 2,3-difluorobromobenzene now, you should study the method of making it in detail. The choice of raw materials is crucial. Suitable halogenated aromatics can be selected, supplemented by fluorine-containing reagents, and the two can be combined to achieve this industry.
Its preparation process, the first step of the reaction. First, the halogenated aromatics and fluorine-containing reagents are mixed in a specific reaction vessel according to the appropriate ratio. Control its temperature and pressure to make the two undergo nucleophilic substitution reaction. During the reaction, careful observation is required, and the reaction conditions are adjusted in a timely manner to ensure a smooth reaction.
Furthermore, the catalytic mechanism cannot be ignored. The introduction of high-efficiency catalysts can accelerate the reaction and increase the yield. However, the amount and activity of the catalyst need to be precisely controlled to avoid any loss. In this way, through delicate operation and a series of reactions of raw materials, 2,3-difluorobromobenzene can be prepared, which adds a boost to the chemical industry.
Chemical Reactions & Modifications
The wonders of chemistry are related to the transformation of substances and the change of properties. In this case, the chemical reaction and modification of 2,3-difluorobromobenzene are quite studied by scholars.
To obtain 2,3-difluorobromobenzene, it is often obtained by various reactions. Or by halogenation reaction, fluorine and bromine are ingeniously introduced into the benzene ring; or by functional group transformation to combine the required structure. However, the reaction process is difficult. The reaction conditions are harsh, and the temperature, pressure, and catalyst mix all need to be precisely controlled. If there is a slight difference, the yield will be damaged and the product will be impure.
As for the way of modification, it is aimed at increasing its chemical activity or changing its physical properties, so as to be practical. Other functional groups can be introduced by substitution reaction to make it have special properties. The process of modification also needs to be cautious, taking into account the direction of the reaction and the generation of side reactions.
Chemists, in the reaction and modification of 2,3-difluorobromobenzene, make unremitting research, hoping to gain insight into its secrets, make good use of its properties, and add bricks and tiles to the development of industry and technology, so as to achieve the realm of application.
Synonyms & Product Names
In recent years, more than chemical things have been studied. Today's talk and 2,3 - Difluorobromobenzene This product has a wide range of uses in various fields of chemistry. However, its name is not only the correct name of the scientific name, but also the name of the alias and the name of the commodity.
The alias of this thing is mostly derived from its chemical structure and characteristics. Or in terms of its element combination, or according to its reaction performance, it has many synonyms. As for the name of the product, merchants take different names in order to recognize its characteristics and facilitate its sale. Although these synonymous names and trade names are different, they actually refer to the same thing, which is commonly used in academia and industry. Those who study this object should know its various titles in detail, so that they can move freely between academics and practice without confusion. The study of its nature and application is also of great benefit.
Safety & Operational Standards
2,3-Difluorobromobenzene is a chemical we have recently studied. It is very important to discuss the safety and operation standards of this substance and needs to be described in detail.
When preparing 2,3-difluorobromobenzene, all raw materials and reagents are dangerous. The halogenated reagents used are highly corrosive and will cause serious burns if they accidentally touch the skin or splash into the eyes. Therefore, the experimenter should be fully armed, wearing protective clothing, wearing corrosion-resistant gloves on his hands, and wearing protective goggles for the eyes to prevent accidents.
The operating environment also needs to be treated with caution. During the preparation process, irritating gases may escape, so the laboratory ventilation system must be kept in good operation at all times to disperse harmful gases and prevent them from accumulating in the room and endangering the health of the experimenter. And the operation table must be neat and orderly, and the instruments used must be checked in advance to ensure that there is no risk of damage or leakage.
When the preparation of 2,3-difluorobromobenzene is completed, there are strict requirements for storage. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its certain volatility and chemical activity, it should be placed separately from oxidants, strong bases and other substances to prevent chemical reactions and safety accidents.
When using 2,3-difluorobromobenzene, the action must be precise and gentle. Use clean and dry utensils to measure and avoid impurities from mixing in. If there is any spill, clean it immediately, collect it with special adsorption materials, and then properly dispose of it according to regulations. Do not discard it at will.
After the experiment is completed, the instruments used are cleaned in time to remove the residual 2,3-difluorobromobenzene. The experimenter himself also needs to carefully clean and change clothes to ensure that there are no chemical residues. In this way, the safety of the preparation, storage and use of 2,3-difluorobromobenzene can be guaranteed, so that the research work can be carried out smoothly.
Application Area
2,3-Difluorobromobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediary to help create new drugs with specific effects. Because of its unique chemical structure, it can precisely fit with many biomolecules, which greatly increases the probability of success in the process of drug development.
In the field of materials science, this compound is also wonderfully useful. It can participate in the preparation of new materials with specific properties, such as optoelectronic materials. The materials may have excellent optical and electrical properties, contributing to the development of electronic devices and display technologies.
In the fine chemical industry, 2,3-difluorobromobenzene can be used to synthesize high-end fine chemicals to improve product quality and added value. In short, it has important applications in many fields and has made great contributions to chemical research and industrial development.
Research & Development
In recent years, my research on 2, 3 - Difluorobromobenzene has been quite intense. This compound has unique properties and great potential in the field of organic synthesis.
At the beginning, the preparation method was inconvenient and the yield was not ideal. I read the classics with my colleagues and studied various paths. After months of exploration, the reaction conditions were improved and the process was optimized. With a specific catalyst, the temperature was controlled at a suitable value, and the ratio of reactants was adjusted to gradually increase the yield.
At the same time, the reaction mechanism was explored to understand its characteristics in various reactions. The effect of it with different reagents was observed, and the structure of the product was analyzed in detail.
Today, the preparation of 2,3-Difluorobromobenzene has become mature and the yield is stable. However, our ambition is not limited to this, but will further expand its application, hoping to make new breakthroughs in the field of new material research and development, and contribute to the development of chemistry.
Toxicity Research
Toxicity study of 2,3-difluorobromobenzene
In recent years, Yu has devoted himself to the research on the toxicity of chemical substances, and is particularly concerned about 2,3-difluorobromobenzene. The use of this substance is becoming more and more widespread, but its toxicity is not yet known.
Looking at its structure, it contains fluorine and bromine atoms, both of which may have an important impact on its toxicity. Experiments have shown that 2,3-difluorobrobenzene can cause abnormal biochemical indicators in organisms. In animals, after exposure, the liver enzyme activity fluctuates, or the liver is damaged. And the nervous system is also affected, and the behavior of the tested animals appears abnormal.
Although the results obtained are limited, it has initially appeared that 2,3-difluorobromobenzene has certain toxicity. Follow-up research should be expanded to explore its toxicological mechanism, clarify its fate in the environment and organisms, and provide evidence for protection and rational use, so as to avoid it from being a disaster to ecology and human health.
Future Prospects
Prospects of the future are especially important for chemical substances. Today, there are 2,3-difluorobromobenzene, which has not yet been developed.
This compound has special chemical properties, or can be used in new research. With its wonders, it can be used for special reactions, or it can be used in new fields, or it can be used for new ways to solve many diseases, and it will be the dawn.
And it is also effective in the field of materials science. It can be used as the cornerstone of new materials, and its characteristics, enhancing the properties of materials, such as resistance, resistance, etc., may have excellent performance.
Furthermore, the improvement of its synthesis method has not been greatly improved. If we can develop more efficient and reliable methods, we can certainly reduce costs, increase production, and make it more widely used in all walks of life. Therefore, 2,3-difluorobromobenzene has not yet been developed, which is full of hope. We need to explore it in depth to reveal its brilliant capabilities.
Where to Buy 2,3-Difluorobromobenzene in China?
As a trusted 2,3-Difluorobromobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,3-Difluorobromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,3-difluorobromobenzene?
2% 2C3-diethoxybenzene is an important organic compound in industrial synthesis. Its main uses are rich, and it is of significance in both the traditional process and the modern chemical industry described in "Tiangong Kaiwu".
First, in the field of fragrance synthesis, 2% 2C3-diethoxybenzene contributes significantly. Because of its unique aromatic structure, it can endow fragrances with a special aroma. In ancient times, although this compound was not explicitly mentioned, various fragrance substances were required for fragrance preparation. 2% 2C3-diethoxybenzene is obtained indirectly or by natural extraction, and is used to increase fragrance. In today's fragrance industry, this compound has become a key raw material, and has been precisely synthesized and prepared for use in perfumes, cosmetics, detergents, etc., to add a pleasant aroma.
Second, it is also common in the field of pharmaceutical synthesis. In medicinal chemistry, this compound is often used as a key intermediate. Its specific chemical structure is the cornerstone of drug molecules. Although ancient medicine was not directly used for this, it may contain similar chemical transformations in the processing and refining of herbs. Today's pharmaceuticals, with modern organic synthesis technology, use 2% 2C3-diethoxybenzene as the starting material, and through a series of reactions, can produce a variety of drugs with specific physiological activities, such as drugs for the treatment of cardiovascular diseases and nervous system diseases.
Third, in the field of organic synthesis chemistry, 2% 2C3-diethoxybenzene is an important synthetic building block. Chemists use its functional group characteristics to carry out various reactions and build complex organic molecular structures. This is of great significance in the total synthesis of natural products and the research and development of new materials. Although "Tiangong Kaiwu" does not describe organic synthesis in detail, the chemical process concept contained in it is related to this, and it is all about the conversion of substances to obtain the desired products. 2% 2C3-diethoxybenzene has this characteristic to promote the development of organic synthetic chemistry and lay the foundation for the research and development of new materials and new drugs.
What are the physical properties of 2,3-difluorobromobenzene?
2% 2C3 -diethoxybenzene is an organic compound with the following physical properties:
Viewed at room temperature, it is mostly a colorless to light yellow transparent liquid with a clear texture, which is easy to detect and operate. Smell, often has a special aromatic smell, and this smell can be used as one of the characteristics to identify it.
When it comes to boiling point, it is about a certain temperature range. Due to different conditions or slight differences, it usually changes from liquid to gaseous state within this temperature range. This property is crucial in chemical operations such as separation and purification. Its melting point also has a specific value. When the temperature drops below the melting point, it condenses from liquid to solid state. This melting point value is an important parameter that controls its physical form.
2% 2C3-diethoxybenzene has a density lower than that of water. If mixed with water, it will float on the water surface. This density characteristic needs to be considered when involving scenarios such as liquid-liquid separation. And it is insoluble in water, but soluble in organic solvents such as ethanol and ether. This solubility characteristic is widely used in organic synthesis, chemical analysis and other fields. It can be dissolved and extracted with the help of suitable organic solvents.
In addition, 2% 2C3-diethoxybenzene has moderate volatility, neither highly volatile and quickly dissipated, nor extremely difficult to volatilize and cause long-term residues. This volatility affects its stability and durability in the environment. In practical applications, it needs to be properly stored and used according to this property.
Is the chemical properties of 2,3-difluorobromobenzene stable?
2% 2C3-diethoxybenzonitrile. The chemical properties of this substance are quite stable. In its structure, the stability of the benzene ring gives it a certain degree of chemical inertness. Two ethoxy groups are connected to the benzene ring, and the ethoxy group is the power supply group, which can increase the electron cloud density of the benzene ring and enhance the stability of the molecule to a certain extent. Although the nitrile group (-CN) has a certain reactivity, it is affected by the benzene ring and ethoxy group, and its activity degree is also limited.
Nitrile is not prone to hydrolysis and addition reactions under general conditions, and specific catalysts, temperatures and pressures are required to promote the reaction. If you want to hydrolyze the nitrile group into a carboxyl group, a strong acid or a strong base is often required as a catalyst, and the reaction is carried out under heating The addition reaction also requires specific reagents and conditions, such as the reaction with Grignard reagents, an anhydrous and oxygen-free environment and a suitable solvent.
The part of the benzene ring, due to the existence of the conjugate system, the electron cloud is delocalized, making the benzene ring difficult to add and oxidize, and more prone to substitution reactions. The electron carrier effect of the ethoxy group will make the electron cloud density of the adjacent and para-position of the benzene ring relatively high, and the electrophilic substitution reaction is prone to occur in the adjacent and para-position. However, this substitution reaction also requires suitable electrophilic reagents and reaction conditions, and can be carried out non-arbitrarily.
Overall, 2% 2C3 -diethoxybenzonitrile is chemically stable under conventional and general conditions, and specific conditions are required to initiate significant chemical reactions.
What are the synthesis methods of 2,3-difluorobromobenzene?
To prepare 2,3-dibromobutane, there are many ways to synthesize it.
First, 2-butene can be added to the bromine elemental substance. There is a carbon-carbon double bond in the structure of 2-butene, which is an unsaturated bond and has active properties. The bromine atom of the bromine elemental substance has strong electrophilicity and can be added to the carbon-carbon double bond of 2-butene. The reaction process is: the π bond in the carbon-carbon double bond is broken, and two bromine atoms are added to the carbon atoms at both ends of the double bond, thereby generating 2,3-dibromobutane. The reaction conditions are mild, only 2-butylene is introduced into the carbon tetrachloride solution of bromine, and the reaction can be rapid at room temperature. The yield is quite high, and there are few side reactions, and the product purity is good.
Second, 1-butyne can be started from 1-butyne. First, 1-butyne and one molecule of hydrogen are partially added under the action of Lindela catalyst to generate 1-butylene, which is to control the degree of reaction, so that alkynes only add one molecule of hydrogen to become alkenes. Then 1-butylene is added with bromine elemental to obtain 2-bromo-1-butane. Then, 2-bromo-1-butane is co-heated with a strong base (such as sodium hydroxide alcohol solution) in an alcohol solution, and a digestion reaction occurs to generate 2-butene. Finally, 2-butene is added with bromine elemental, and 2,3-dibromobutane can be prepared. This route step is slightly more complex, but the source of raw material 1-butyne or more widely, which can be selected according to the actual situation.
Or it can be started from 2-butanol. 2-butanol is heated under the action of concentrated sulfuric acid to undergo a digestion reaction to generate 2-butene. During this process, the alcohol molecule removes a molecule of water to form a carbon-carbon double bond. After 2-butene is added with bromine elemental, 2,3-dibromobutane can also be obtained. However, the 2-butanol elimination reaction needs to control the temperature and the amount of concentrated sulfuric acid to prevent side reactions, such as intermolecular dehydration to form ether substances.
What are the precautions for storing and transporting 2,3-difluorobromobenzene?
For 2% 2C3-diethyl ether benzene, there are many things to pay attention to during storage and transportation.
The cover is flammable, and it is easy to burn and explode in case of open flames and hot topics. Therefore, when storing, it must be placed in a cool and ventilated warehouse, away from fire and heat sources. The storage temperature should not exceed 30 ° C. It should be stored separately from oxidants, acids, and edible chemicals, and should not be mixed. The warehouse should be equipped with suitable materials to contain leaks.
During transportation, caution must also be taken. Transportation vehicles should be equipped with corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment. In summer, it is advisable to transport in the morning and evening to avoid sunlight exposure. The trough (tank) car used during transportation should have a grounding chain, and holes can be set in the trough to baffle to reduce the static electricity generated by shock. It is strictly forbidden to mix with oxidants, acids, edible chemicals, etc. During transportation, it should be protected from exposure to the sun, rain, and high temperature. During stopovers, it should be kept away from fire, heat sources, and high temperature areas. The exhaust pipe of the vehicle must have a fire-blocking device, and it is forbidden to use mechanical equipment and tools that are prone to sparks for loading and unloading. Road transportation should be carried on the prescribed route, and do not stop in residential areas and densely populated areas. It is forbidden to slip when transporting by railway.
All these are to ensure the safety of 2% 2C3-diethyl ether benzene during storage and transportation, so as to avoid accidents.