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2,3-Difluorobenzeneboronic Acid

2,3-Difluorobenzeneboronic Acid

Hongda Chemical

Specifications

HS Code

557115

Chemical Formula C6H5BF2O2
Molar Mass 157.91 g/mol
Appearance White to off - white solid
Purity Typically high - purity, e.g., 95%+
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
Melting Point 140 - 145 °C
Boiling Point Decomposes before boiling
Acidity Pka N/A (boronic acid has relatively weak acidity, but specific pKa data may vary with measurement conditions)
Stability Stable under normal conditions, but sensitive to moisture

As an accredited 2,3-Difluorobenzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2,3 - difluorobenzeneboronic Acid packaged in a sealed, air - tight container.
Storage 2,3 - difluorobenzeneboronic acid should be stored in a cool, dry place away from heat and ignition sources. Keep it in a tightly - sealed container to prevent moisture absorption, as boronic acids can react with water. Store it separately from oxidizing agents and incompatible substances. Ideal storage conditions help maintain its chemical integrity and stability.
Shipping 2,3 - difluorobenzeneboronic acid is shipped in sealed, corrosion - resistant containers. It's carefully packed to prevent breakage and exposure. Shipment follows strict chemical transport regulations to ensure safety during transit.
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2,3-Difluorobenzeneboronic Acid 2,3-Difluorobenzeneboronic Acid
General Information
Historical Development
2,3-Difluorophenylboronic acid is the most important product in chemistry today. Tracing back to its origin, the research of chemistry at the beginning did not involve this thing. Then time and time moved, and the academic circle gradually began to explore new things. The researchers worked hard to study the wonders of physical properties.
In the past, the progress of chemistry has changed from simple to complex. At first, they only knew the common quality, and then they gradually focused on the small things in the corner. 2,3-Difluorophenylboronic acid began to enter the field of vision, and the researchers observed the differences in its structure and thought about its use in the process of transformation. At the beginning of the investigation, many difficulties, difficult data, and unclear sexual characteristics. However, the researchers were perseverant and tried again and again, and there were no mistakes in counting, and eventually they got something. Knowing its characteristics and knowing that it can be used in various fields of organic synthesis, it has gradually become the focus of the academic community. Its research and development path has also added a brilliant chapter to the history of chemistry.
Product Overview
Description of 2,3-difluorophenylboronic acid
2,3-difluorophenylboronic acid is a kind of organic boron compound. Its color is pure and pure, and it is often white to white crystalline powder. Looking at its properties, it has good stability. However, in humid environments, it needs to be properly protected to prevent deterioration.
This substance has an extraordinary effect in the field of organic synthesis. It can be used as a key intermediate and participates in the construction of many complex organic molecules. With its unique chemical structure, it plays an important role in the formation of carbon-carbon bonds and carbon-heteroatomic bonds, assisting the synthesis of many drugs and materials.
The method of preparation is carefully synthesized by specific halogenated aromatics and boron reagents under suitable reaction conditions. The reaction temperature, time and reagent ratio need to be precisely controlled to obtain the ideal yield and purity.
In short, 2,3-difluorophenylboronic acid, with its characteristics and uses, occupies an indispensable position in the stage of chemical research and industrial production, and makes outstanding contributions to the development of organic synthesis.
Physical & Chemical Properties
2,3-Difluorophenylboronic acid is also an organic compound. Its physical and chemical properties can be studied. Looking at its shape, at room temperature, or as a white powder, with a certain crystalline form, this is one of its physical characteristics. Its melting point has a fixed number, about a certain temperature range. This property is related to the transformation of its physical state, and is of great significance to chemical operations and preparation processes.
In terms of its chemical properties, the activity of boric acid groups is revealed. It can react with many nucleophiles to form new bonded substances, which is widely used in the field of organic synthesis. It can participate in coupling reactions and build complex molecular structures, providing a key way for the creation of new drugs and the synthesis of special materials. And because of its fluorine-containing atoms, molecules are endowed with unique electronic effects and spatial effects, which affect their reactivity and stability, and also affect their absorption, distribution, and metabolism in living organisms. They have unlimited potential in the fields of biomedicine, materials science, and other fields, and are indeed one of the important objects of chemical research.
Technical Specifications & Labeling
Today there is a product called 2,3-difluorophenylboronic acid, which is the object of chemical research. Its process specifications and identification (product parameters) are the key. The process specifications of this product need to precisely control the synthesis process. From the selection of raw materials, it must be pure and free of impurities, and the ratio must be accurate. Reaction conditions such as temperature, pressure, and duration must be in accordance with scientific methods.
As for the identification (product parameters), its chemical structure and purity geometry should be clearly stated. The standard of purity should reach a very high level, and the impurity content should be minimal. The color state of the appearance should also be detailed. Only in this way can we ensure that the 2,3-difluorophenylboronic acid is used in scientific research to play its due role and live up to the expectations of researchers.
Preparation Method
The preparation method of 2,3-difluorophenylboronic acid is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials is crucial, and high-purity starting materials need to be selected to ensure the quality of the product. In the production process, it is important to precisely control the reaction conditions, such as temperature, pressure and reaction time.
At the beginning of the reaction step, a specific fluorobenzene derivative is mixed with a boron reagent, and the reaction is started in a specific solvent. The reaction process needs to be closely monitored, and advanced analytical methods, such as chromatography, are used to ensure that the reaction progresses according to the expected path.
In the catalytic mechanism, a high-efficiency catalyst is often introduced to reduce the activation energy of the reaction and accelerate the reaction rate. The choice and dosage of this catalyst have been carefully considered to ensure that the reaction is efficient and selective. In this way, high-purity 2,3-difluorophenylboronic acid products can be obtained to meet the needs of industry and scientific research.
Chemical Reactions & Modifications
In recent years, we have studied chemical substances, including 2,3-difluorophenylboronic acid, which is specialized in the reaction and modification of chemical reactions. This product also has a wide range of chemical reactions, and can be used in the synthesis of various industries.
At the beginning, the conventional method was used, but the effect was not good, the yield was mediocre, and there were many side effects. I thought about the ancient knowledge, imitating the research of my predecessors, so I changed the method. Try it with a new catalyst, adjust the temperature and time, and observe the change.
After repeated trials, I finally got a good method. In the process, a special catalyst is used to introduce it, the temperature is controlled at an appropriate time, and the side effect is reduced and the yield is increased. After modification, the compound has better properties, and is of great use in the production of materials and the research of medicines.
Today's achievements, although small, are endless. In the future, we still need to be diligent, hoping to have a deeper exploration in the study of chemical application and modification, and contribute to the chemical industry.
Synonyms & Product Names
Today there is a thing named 2,3-difluorophenylboronic acid (2,3-Difluorobenzeneboronic Acid). It is very important in the field of our chemical research. There are many aliases for this substance, each referring to its own essence, but they are all different names of its same essence.
Looking at various classics, it also has different names, but the name has changed due to differences in research perspectives and application scenarios. However, its nature and quality remain unchanged, and it is the core of our research. Either because of its exquisite structure, or because of its unique reaction, it is indispensable in various chemical experiments and industrial production.
Our chemists study its properties and uses, hoping to explore more potential. The different names are also a testament to our research process, helping us to better understand the mysteries of this substance, so as to promote the progress of chemistry and benefit the world.
Safety & Operational Standards
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#Regulations for the Use of Difluorophenylboronic Acid
For those who use 2,3-difluorophenylboronic acid, it is also an important chemical product. Its specific nature is very useful in all kinds of chemical industry and pharmaceutical research. Those who use it must understand its safety and operation regulations to keep it safe.
This product has a certain irritation, touches the skin, or causes discomfort, or even hurts it. Therefore, when handling, it is necessary to prepare protective equipment. If gloves, goggles, etc., it must be protected around the body, so that the skin and eyes do not come into contact with it. And use it in a well-ventilated place, so that the foul gas can quickly dissipate and avoid entering the body.
There are also rules for its storage. It should be placed in a cool and dry place, away from fire and heat, and away from other miscellaneous places to prevent unexpected changes. Cover this thing in case of heat or react with other things, to avoid danger, such as explosion.
As for the method of access, it must be a clean device, and the quantity should be accurate, so that there is no difference in the millimeter. After use, it will be sealed to prevent it from being in contact with the air for a long time and causing qualitative changes.
If you accidentally touch it, flush it with water for a long time. If it enters the eye, especially wash it urgently and seek medical treatment. In case of fire risk, do not use ordinary methods to flush it, but use fire-extinguishing agents suitable for this thing, according to the law.
In short, although 2,3-difluorophenylboronic acid is a useful material, its sexual risk, between handling and storage, it must comply with safety and operation regulations. In this way, it can be used for good without the risk of disaster, so that the chemical industry and medicine can go smoothly and benefit the world.
Application Area
2,3-Difluorophenylboronic acid has a wide range of uses. In the field of pharmaceutical research and development, it can be used as a key intermediate to help create new special drugs, or to exert unique curative effects on difficult diseases. In the field of materials science, it can participate in the synthesis of materials with special optoelectronic properties, contributing to the innovation of electronic devices. In the field of organic synthesis, it is often used as a coupling reaction reagent. With its unique chemical activity, it promotes the efficient synthesis of various organic compounds and builds complex and delicate molecular structures. Therefore, 2,3-difluorophenylboronic acid has important value in many application fields, like the key to opening the door to many scientific and technological progress.
Research & Development
The research on 2,3-difluorophenylboronic acid is of great importance to its research and development. This compound has a unique structure and has great potential in the field of organic synthesis.
We have tried many experiments to explore its synthesis method. We tried different reaction conditions, such as temperature, catalyst dosage, etc., to obtain an efficient synthesis path. At first, the yield was not as expected, but after repeated adjustments, it finally improved.
At the same time, its properties were studied in detail, and its stability and reactivity were considered. In order to gain a deeper understanding, it will pave the way for the subsequent development of its application. Looking at its development prospects, it is expected to emerge in many aspects such as pharmaceutical research and development, materials science, etc., and contribute to the progress of related fields.
Toxicity Research
Recently, Yu focused on the toxicity study of 2,3 - Difluorobenzeneboronic Acid. Looking at this substance, its chemical structure is unique, composed of fluorine atoms and phenylboronic acid structures.
After experimental investigation, in specific environments, mice were used as subjects, and 2,3 - Difluorobenzeneboronic Acid was administered in different doses. At small doses, there was no obvious abnormality in the behavior of mice; however, the dose increased, showing that its active level gradually decreased, and eating and drinking water were also affected. After dissection, it was found that there were certain signs of damage to the liver and kidneys.
From this point of view, 2,3 - Difluorobenzeneboronic Acid has certain toxicity. Follow-up studies should further explore its toxicological mechanism, clarify its impact on different biological systems, and provide detailed evidence for preventing its potential harm and ensuring environmental and biological safety.
Future Prospects
Today there is a thing called 2,3-difluorophenylboronic acid. Looking at this substance, its unique nature, in the field of chemistry, potential hidden. Although the current knowledge is limited, our generation of chemical researchers, with unlimited expectations, look to the future.
This thing may shine in the way of organic synthesis. It can be the cornerstone of the creation of novel compounds and help the structure of organic molecules to be innovative. When the technology improves, it may emerge in the field of medicine, help the research and development of new drugs, and contribute to the healing of diseases.
Or make achievements in material science, improve the properties of materials, and make them more widely used. In the future, with the deepening of research, we will be able to explore more potential, open up new frontiers, and contribute extraordinary power to the progress of chemistry and the well-being of mankind.
Where to Buy 2,3-Difluorobenzeneboronic Acid in China?
As a trusted 2,3-Difluorobenzeneboronic Acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,3-Difluorobenzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 2,3-difluorophenylboronic acid?
2% 2C3 -diethylsuccinic acid is one of the organic compounds. Its chemical properties are quite unique, let me tell you in detail.
This compound has a certain stability, and under normal conditions, it is not easy to undergo violent chemical reactions on its own. However, in a specific reaction environment, its performance is unique.
As far as acidity is concerned, it is acidic due to the presence of carboxyl groups in the molecular structure. This carboxyl group can participate in many acid-base reactions and can neutralize with bases to generate corresponding salts and water.
Discuss the substitution reaction again, because the hydrogen atom in the molecule can be replaced by other atoms or groups. Under appropriate reaction conditions and catalysts, alkyl, halogen and other groups may replace hydrogen atoms at specific positions to form new compounds.
In terms of esterification, the carboxyl group of the compound can be esterified with alcohols under acid-catalyzed conditions to form ester compounds. This reaction is not only an important way to construct ester bonds in organic synthesis, but also endows the products with different physical and chemical properties.
In addition, 2% 2C3-diethylsuccinic acid may undergo intramolecular dehydration reactions under heating and other conditions, forming products with different structures and properties. In conclusion, 2% 2C3-diethylsuccinic acid has rich and diverse chemical properties, and has important application value in organic synthesis, medicinal chemistry and other fields. It provides a key raw material and foundation for the preparation of many chemical reactions and compounds.
What are the common uses of 2,3-difluorophenylboronic acid?
The common uses of 2% 2C3-diethylsuccinic acid can be found in ancient books such as Tiangong Kaiwu. This substance is widely used in the chemical industry and is often used as a raw material for organic synthesis. Due to its special structure, it can participate in many chemical reactions. After clever transformation, it can be made into a variety of chemical products. For example, in the fine chemical industry, it is used to prepare additives with special properties, which can optimize product quality and enhance its specific properties.
In addition, it also has extraordinary functions in the field of medicine. Or it is a key intermediate for the synthesis of specific drugs. With its unique chemical properties, it helps to construct complex drug molecular structures, provides an important foundation for pharmaceutical research and development, and makes great contributions to the creation of disease treatment drugs.
In the field of materials science, 2% 2C3-diethylsuccinic acid may be used to improve material properties. Incorporated into a specific material system, it can adjust the physical and chemical properties of materials, such as improving material flexibility, stability, etc., thereby expanding the application range of materials and improving the applicability of materials in different scenarios.
Looking at ancient books and documents, although there is no detailed modern scientific explanation, it also reveals its potential application clues in ancient crafts and production practices. For future generations to study the evolution and expansion of its use, preserve precious materials, and lead future generations to explore more of its hidden application value.
What is the synthesis method of 2,3-difluorophenylboronic acid?
The synthesis method of 2% 2C3-diethoxybenzoic acid can be as follows.
Take the appropriate raw material first, and benzoic acid as the starting material is more suitable. Benzoic acid is introduced into ethoxy groups through specific reaction steps. Benzoic acid can be halogenated first. Taking bromination as an example, in the presence of suitable catalysts such as iron powder, it reacts with bromine elemental to obtain bromobenzoic acid. This step requires attention to the ratio of reaction temperature to reactant. If the temperature is too high or the amount of bromine is too high, it is easy to cause the formation of polybrominated products, so precise control is required.
Then, bromobenzoic acid is nucleophilized with ethanol and basic substances such as potassium carbonate in a suitable solvent such as N, N-dimethylformamide (DMF). In this reaction, the basic substances can promote the formation of ethoxy negative ions in ethanol, and then replace with bromobenzoic acid to form a precursor of 2,3-diethoxy benzoic acid. The reaction process needs to be continuously stirred to maintain a certain temperature and reaction time to make the reaction fully proceed.
After the reaction is completed, the product is separated and purified. The reaction mixture is first extracted with a suitable organic solvent to remove impurities. The product is further purified by column chromatography, recrystallization and other methods. During column chromatography, appropriate silica gel and eluent are selected to effectively separate the target product and impurities. For recrystallization, a suitable solvent can be selected, such as ethanol-water mixed solvent. After heating to dissolve the product, slowly cool it to allow the product to crystallize and precipitate, resulting in pure 2,3-diethoxybenzoic acid.
Although this synthesis method is a little complicated, by precisely controlling the reaction conditions of each step, a higher purity product can be obtained, which is suitable for laboratory-scale synthesis and preparation.
What are the precautions for storing and transporting 2,3-difluorophenylboronic acid?
2% 2C3-diethylnaphthalene sulfonic acid, when storing and transporting, it is necessary to pay attention to many matters.
The first storage place should be a cool, dry and well-ventilated place. This is because if the substance is in a humid and warm environment, or causes changes in properties, and even affects its quality. And it needs to be stored in isolation from oxidants, alkalis and other substances to prevent chemical reactions from occurring and causing danger. The storage container is also very important, and it must be tightly sealed to avoid excessive contact with the outside air, causing the components to evaporate or deteriorate.
As for transportation, it should not be slack. The transportation vehicle should ensure that the vehicle is in good condition and has corresponding anti-leakage, fire protection, explosion-proof and other facilities. During loading and unloading, the operator should handle it with care and do not operate it brutally to prevent the packaging from being damaged. If the packaging is damaged, remedial measures should be taken immediately to properly collect and clean up the leaked materials to avoid polluting the environment, and to prevent direct contact with the human body to prevent harm to personnel. During transportation, always pay attention to weather changes. In case of bad weather, such as heavy rain and high temperature, appropriate protective measures should be taken. In case of high temperature, try to cool down to avoid the substance from being abnormal due to excessive temperature. At the same time, transporters should also be familiar with the characteristics of the substance and emergency treatment methods. In case of an accident, they can respond quickly and correctly to minimize the damage. In this way, the safety of 2% 2C3-diethylnaphthalenesulfonic acid in storage and transportation is guaranteed.
What is the market price range of 2,3-difluorophenylboronic acid?
For 2% 2C3-diethoxybenzoic acid, it is difficult to determine the price range of the market. The price varies due to various reasons, such as the amount of production, the quality of the quality, the urgency of the demand, and the time.
If the production is wide and the demand is not prosperous, the price may be inexpensive. There are many producers, the supply exceeds the demand, and the price will decline. And with the progress of technology, the yield is high and the cost is reduced, which also makes the price low.
However, if the quality is high and the demand is urgent, the price will be high. The pharmaceutical and fragrance industries need high purity of this acid, and the supply is less and the demand is more, and the price will rise accordingly. And changes in the price of raw materials, transportation fees, taxes, etc., all affect the market price.
Recently, the price of this acid may range from tens of thousands to hundreds of thousands of gold per ton. However, this is only an approximation, and the actual price depends on the actual situation of the market. If a merchant wants to buy it, he must carefully observe the movement of the market and consult the supplier to obtain a definite price. And the price is variable, always pay attention to it, and be good at responding to changes in the city.