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2,3-Difluorobenzeneacetic Acid

2,3-Difluorobenzeneacetic Acid

Hongda Chemical

Specifications

HS Code

406600

Chemical Formula C8H6F2O2
Molar Mass 172.13 g/mol
Appearance Solid
Melting Point 54 - 58 °C
Boiling Point 260 - 262 °C
Solubility In Water Low solubility, being an organic acid with hydrophobic benzene ring
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone, etc.
Acidity Pka Typical of aromatic carboxylic acids, around 3 - 5

As an accredited 2,3-Difluorobenzeneacetic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250g of 2,3 - difluorobenzeneacetic acid packaged in a sealed, corrosion - resistant bottle.
Storage 2,3 - difluorobenzeneacetic acid should be stored in a cool, dry, and well - ventilated area. Keep it away from sources of heat, ignition, and oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and evaporation. Label the storage container clearly to avoid misidentification. It is advisable to store it in a dedicated chemical storage cabinet for safety.
Shipping 2,3 - difluorobenzeneacetic acid is shipped in properly sealed, corrosion - resistant containers. Shipment follows strict chemical transportation regulations to ensure safety during transit, protecting from spills and environmental exposure.
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2,3-Difluorobenzeneacetic Acid 2,3-Difluorobenzeneacetic Acid
General Information
Historical Development
In the past, I have studied the mystery of 2,3-difluorophenylacetic acid on the road of chemical research. At the beginning, this compound has not been revealed in the world, and it has not been studied in detail by all ancestors. My colleagues and I, over the years, have expended a lot of effort, and we have begun to get a glimpse of it.
At the beginning, we searched for its source and searched for various ancient books, but we have not found it. So we found a way to explore the synthesis method. First, we used benzene as the basis, applied fluoridation techniques, and tried hard to find it. After several years, we have repeatedly inferred the reaction strip and the matching of materials, and gradually obtained something. After many trials, the synthesis method has gradually become perfect, and the yield has gradually increased.
This compound has been hidden in the secluded world until it appears in front of the public, and has gone through twists and turns. Our efforts are not for our own glory, but to open a new chapter in chemistry, paving the way for future researchers, hoping that it will go further in the study of this thing and benefit the world.
Product Overview
2,3-Difluorophenylacetic acid, which is an important intermediate in organic synthesis. Its properties are white to off-white crystalline powder with specific physical and chemical properties. The melting point is within a certain range and exhibits specific solubility in organic solvents.
In the field of synthesis, it is often prepared by a specific organic reaction path. In its chemical structure, benzene cyclic is a difluorine substituent and an acetic acid group, giving it unique reactivity. With this structural property, it can participate in many organic reactions, such as esterification, amidation, etc., and is widely used in medicine, pesticide creation, etc. It can build key structural fragments for new drug molecules or be used as an important raw material for the synthesis of pesticide active ingredients, which is of great significance to promote the development of related fields.
Physical & Chemical Properties
2,3-Difluorophenylacetic acid has unique physical and chemical properties. Looking at its state, at room temperature, it is mostly solid, pure in color and uniform in quality. On the point of melting and boiling, the melting point is quite fixed, which can be a sign of identification; the boiling point varies slightly according to external air pressure.
As for solubility, it is soluble and meltable in organic solvents such as ethanol and ether, but it is less soluble in aqueous media. This is due to the structure of the molecule, which contains benzene rings and fluorine atoms, which are hydrophobic, while the carboxyl group is hydrophilic, but it is not as strong as hydrophobicity.
Its chemical activity, the fluorine atom on the benzene ring, makes the electron cloud density of the benzene ring change, so that it is different from the conventional benzene derivatives in the electrophilic substitution reaction. Carboxyl groups can react with bases to form salts, and can also react with alcohols to esterify to obtain ester products. All of these are important physicochemical properties of 2,3-difluorophenylacetic acid.
Technical Specifications & Labeling
Process Specifications and Labeling (Product Parameters) of 2,3-Difluorophenylacetic Acid
There is currently 2,3-Difluorophenylacetic Acid. Its process specifications and preparation must be strictly followed by specific methods. The selection of raw materials should be carefully selected, and the proportion of each ingredient must be accurate. The reaction conditions are also critical, and the temperature, duration, pressure, etc. must be properly regulated.
In terms of its identification, the appearance of the product should be clear, and the color, shape, etc. should meet the established standards. The ingredients, purity and other product parameters contained in it must be accurately identified. In this way, the high-quality 2,3-difluorophenylacetic acid can be obtained, and it will play its due role in subsequent applications.
Preparation Method
The preparation of 2,3-difluorophenylacetic acid is related to the raw materials, production process, reaction steps and catalytic mechanism, which is the gist of chemical research.
To prepare 2,3-difluorophenylacetic acid, the raw materials need to be selected first. Appropriate fluoroaromatic hydrocarbons and carboxylic acid derivatives with specific activities are used as starting materials, which lay the material foundation in the initial stage of the reaction.
The production process is constructed by a multi-step reaction. The first step is to promote the clever combination of fluoroaromatic hydrocarbons and specific reagents according to the mechanism of nucleophilic substitution, and introduce specific groups into the aromatic ring. The reaction conditions in this step need to be precisely controlled. The choice of temperature and solvent will affect the reaction process and yield.
In the second step, after a series of conversions, the primary product is gradually approached to the target product by suitable oxidation or substitution means. Each step of the reaction, from the order of reagent addition to the reaction time, must strictly follow the established procedures.
And the catalytic mechanism is also crucial. The selection of efficient catalysts, such as specific metal complexes or organic small molecule catalysts, can greatly increase the reaction rate, reduce the reaction activation energy, guide the reaction to generate 2,3-difluorophenylacetic acid efficiently, optimize the entire preparation process, and improve the purity and yield of the product.
Chemical Reactions & Modifications
There is now a substance called 2,3-difluorophenylacetic acid. In the field of chemistry, its reaction and modification are quite critical.
To understand its chemical reaction, it is necessary to investigate its molecular structure in detail. In this compound, the position of the benzene ring has a difluorine substitution, and there is an acetic acid group attached. The strong electronegativity of the fluorine atom has a great impact on the electron cloud distribution of the benzene ring, which changes the electron cloud density of the benzene ring and the para-site, thereby affecting the activity and check point of the electrophilic substitution reaction.
When talking about modification, it can be started at the benzene ring or the acetic acid group. For example, through specific chemical reactions, other functional groups are introduced into the benzene ring to change its physical and chemical properties. Or modify the acetic acid group to change its acidity, hydrophilicity, etc. In this way, 2,3-difluorophenylacetic acid may have better applications in medicine, materials and other fields, opening up a new way for chemical research and practice.
Synonyms & Product Names
Today there is a thing called 2,3-difluorophenylacetic acid (2,3-Difluorobenzeneacetic Acid). The synonyms and trade names of this thing are also investigated by us. The synonyms of the husband are the names of the thing. Although the expressions are different, they refer to the same thing. As for the trade name, the name given by the merchant in recognition of the uniqueness of its product is also.
In the field of chemistry, synonyms can help scholars understand the essence of this thing. Although the names are different, they all refer to this specific compound. The trade name is easy for consumers to recognize and remember when it is in the market. 2,3-difluorophenylacetic acid, or various synonyms, are all agreed upon by the chemical community to facilitate academic exchanges. The design of the trade name is designed to make it stand out in the commercial environment with a unique logo. Both of these are essential to the dissemination and application of the thing and cannot be ignored.
Safety & Operational Standards
Specifications for safety and operation of 2,3-difluorophenylacetic acid
Fu 2,3-difluorophenylacetic acid is an important substance in chemical research. Safety and standardized operation are essential in its experimental and production links.
As far as storage is concerned, it must be placed in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent them from changing their properties due to heat or even causing danger. And it must be stored separately from oxidants, alkalis, etc., and must not be mixed with storage, due to the interaction of different chemicals, or unexpected changes.
When operating, the experimenter should be fully protected. Wear suitable protective clothing to prevent it from coming into contact with the skin and causing skin damage. Wear protective gloves to ensure the safety of your hands. Protective glasses are also indispensable to protect your eyes from harm.
If you accidentally come into contact with this object during operation, dispose of it as soon as possible. If it touches the skin, rinse with a large amount of flowing water immediately, and the duration should be sufficient to ensure that all the residues are removed, and then seek medical treatment to ensure that there is no future disease. If it splashes into the eyes, it should also be rinsed with flowing water or normal saline immediately, and then rushed to the hospital.
When discarding, it should also be done according to the regulations. It should not be discarded at will, but must be handed over to a professional treatment agency in accordance with relevant regulations to properly dispose of it and avoid pollution to the environment. This way, we can ensure the safety of the experiment and protect the environment and ecology.
Application Area
2,3-Difluorophenylacetic acid has a wide range of application fields. In the field of pharmaceutical research and development, it can be a key intermediate, help to create new drugs, or have unique curative effects on specific diseases. In the field of chemical synthesis, it can participate in many organic synthesis reactions to prepare other fine chemicals and enrich the types of chemical products.
Although the ancient technology is not as developed as it is today, there are also methods for material exploration and application. Today's 2,3-difluorophenylacetic acid is the foundation of previous exploration, followed by scientific methods and in-depth research. Its application continues to expand, or it will add a bright color to the future medical and chemical field, benefiting the world and benefiting all people.
Research & Development
In recent years, I have dedicated myself to the research of 2,3 - Difluorobenzeneacetic Acid. This compound has unique properties and has great potential in the fields of medicine and materials.
At the beginning, the synthesis method was full of thorns, the yield was low, and there were many impurities. However, I did not give up. After many tests, the reaction conditions were improved, and the suitable catalyst was selected. The yield gradually increased and the quality was excellent.
During the study, the relationship between its structure and properties was also explored. To clarify its characteristics, paving stones for applications. Today, this achievement has seen the dawn, and it is expected to be promoted in industrial production, add new color to the industry, and on the road of research and development, although it has been difficult to prepare, I firmly believe that unremitting research will be able to promote its wide application and help scientific research and development.
Toxicity Research
The study of toxins in modern times is related to the health of people's livelihood and cannot be ignored. Today, based on 2,3-Difluorobenzeneacetic Acid, we want to investigate its toxicity.
The toxicity of this substance should be carefully examined in its chemical properties and configuration. Observe its molecular structure, fluoride-containing basis, fluoride, sexual activity, or toxic changes. In living organisms, it may disturb the order of biochemistry and disrupt the cells.
If you want to understand the details, you must use the experimental evidence. Observe its effect on various organisms, observe its response to animal bodies, and examine the changes that occur after its entry into the body, such as damage to organs and obstacles to metabolism.
And consider it in the shadow of the environment, scattered in water and soil, or harmful to the surrounding creatures. Although the research is not yet complete, the research on toxicity must be done with caution to ensure the safety of all beings and the environment. This is the heavy responsibility of our researchers, and we must not be lazy.
Future Prospects
The future prospect of 2,3-difluorophenylacetic acid is related to the exploration path of our generation of chemical researchers. This compound has unique chemical properties and may have extraordinary potential in the field of organic synthesis.
At present, although there have been many studies, the unknown is still vast. In the future, it may emerge in the research and development of medicine. With its special structure, we can develop special new drugs to save patients and diseases. In materials science, new functional materials may also be derived to meet the needs of scientific and technological development.
Our chemical researchers should explore the mysteries of 2,3-difluorophenylacetic acid with enthusiasm for exploration and a rigorous attitude. With time, we will be able to open up new horizons, add a bright light to the academic world and the world, achieve an extraordinary career, live up to the mission of scientific research, and develop the grand future.
Where to Buy 2,3-Difluorobenzeneacetic Acid in China?
As a trusted 2,3-Difluorobenzeneacetic Acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,3-Difluorobenzeneacetic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,3-difluorophenylacetic acid?
2% 2C3-diethoxybutyric acid, in the eyes of many Fang families throughout the ages, has an extraordinary use.
In the process of alchemy cultivation, its effectiveness is quite critical. Gaiyin alchemy is aimed at reconciling the body and mind, and reaching the realm of unity between heaven and man. This diethoxybutyric acid can help alchemists reconcile the medicinal properties of the cauldron. As the "Fellowship Agreement" said, "When gold comes to return, it is called returning pills". In the process of refining returning pills, it is necessary to precisely prepare various medicinal stones. 2% 2C3-diethoxybutyric acid is included in it, which can make the medicinal properties more delicate, catalyze the formation of medicinal pills, and help practitioners form golden pills as soon as possible, achieving extraordinary body.
In the medical way of treating diseases and saving people, 2% 2C3-diethoxybutyric acid is also indispensable. Doctors treat diseases, pay attention to syndrome differentiation and treatment, and correct the deviation of the human body with the bias of drugs. This acid can enter the liver meridian and kidney meridian. If people are deficient in liver and kidney, resulting in poor qi and blood, soreness of waist and knee, dizziness, and dizziness, 2% 2C3-diethoxybutyric acid can play its role in dredging meridians and nourishing liver and kidney. Just as the Yellow Emperor's Nei Jing states that "righteous qi is stored in the body, and evil cannot be dried", by regulating the functions of human organs, it enhances righteous qi and resists the invasion of external evil, so that patients can regain health.
Furthermore, it also has wonderful uses in utensils. For example, in the art of pottery, clay shaping and firing, to make pottery delicate in texture and warm in color, 2% 2C3-diethoxybutyric acid can be used as a special additive. When mixing clay, adding an appropriate amount of this material can change the clay's viscosity and plasticity. The fired pottery has a smooth surface like a mirror, and is sturdy and durable, adding many exquisite utensils to the world and enriching the use of life.
What are the physical properties of 2,3-difluorophenylacetic acid?
2% 2C3-diethylsuccinic acid is an organic compound with specific physical properties. Its properties are usually white crystalline powder, which is pure and white and has a fine texture. The melting point of this substance is about 120-124 ° C. At this temperature, it will gradually change from a solid state to a liquid state, showing the characteristics of a material state transition.
When it comes to solubility, 2% 2C3-diethylsuccinic acid is slightly soluble in water. In water, only a small amount can be evenly dispersed, just like fine dust fused into a stream. Although it can be fused, the amount is small. However, it has good solubility in organic solvents such as ethanol and ether. Just like a fish entering the sea, it can quickly blend with organic solvents to form a uniform system.
In addition, the density of 2% 2C3-diethylsuccinic acid is also an important physical property. Under normal temperature and pressure, its density is maintained at a certain value, giving the substance a specific weight and volume relationship. This density characteristic is of great significance in many practical application scenarios, such as material measurement, separation and purification in chemical production.
It also has certain stability, and can maintain its own chemical structure and properties under normal environmental conditions. However, in the event of extreme conditions such as high temperature, strong acid, and strong alkali, its chemical stability may be affected, or chemical reactions may be initiated, resulting in changes in molecular structure and the formation of new substances.
Is the chemical properties of 2,3-difluorophenylacetic acid stable?
2% 2C3 -diethylaminoacetyl acid, this is an organic compound. The stability of its chemical properties needs to be examined in detail from various angles.
Looking at its structure, the molecule contains the part of diethylamino and acetyl acid. In the diethylamino group, the nitrogen atom has a lone pair of electrons, which can be used as an electron donor and participate in many chemical reactions. This group makes the molecule alkaline and can react with acids to form corresponding salts. The acetyl acid part contains a carboxyl group, which is acidic and can dissociate hydrogen ions and neutralize with bases.
From the perspective of stability, this compound is relatively stable at room temperature and pressure without the action of special chemical reagents. However, if placed under extreme conditions such as high temperature, strong acid and alkali, or strong oxidizing agents, its stability may be destroyed. For example, in a strong acid environment, both carboxyl and diethylamino groups will react with acids, causing molecular structure changes. In case of strong oxidizing agents, some chemical bonds in the molecule may be oxidized and broken, causing the compound to decompose.
In addition, the stability of the compound is also affected by solvents. In polar solvents, the stability is affected by the interaction between the solvent and the molecule, or by changing the distribution of its electron cloud. In non-polar solvents, the intermolecular forces are different, and may have different effects on its stability.
Overall, 2% 2C3-diethylaminoacetic acid is relatively stable under ordinary conditions, but in the case of special chemical environments or specific reagents, its stability is difficult to maintain, and various chemical reactions will occur, causing molecular structure changes.
What are the synthesis methods of 2,3-difluorophenylacetic acid?
There are several common methods for synthesizing 2% 2C3-diethoxybutyric acid.
One is to use the corresponding carboxylic acid derivative as the starting material. For example, a compound containing a carboxyl group is used to convert the carboxyl group through specific reaction conditions, and an ethoxy group is introduced at the same time. The carboxyl group can be activated first, such as by converting it into the form of an acyl chloride, and then reacted with ethanol under the catalysis of a base. In this process, the base can promote the reaction, so that the hydroxyl group of ethanol is substituted with the chlorine of the acyl chloride, thereby introducing an ethoxy group. Then through appropriate reaction steps, the molecular structure is adjusted to achieve the purpose of generating 2% 2C3-diethoxybutyric acid.
Second, the reaction involving organometallic reagents can be used. Select suitable halogenated hydrocarbons and react with metal reagents to form organometallic compounds. The compounds have active carbon-metal bonds, which can undergo nucleophilic addition reactions with carbonyl-containing compounds. Afterwards, the addition products are processed, and under suitable conditions, the carbonyl groups are converted to carboxyl groups, and ethoxy groups are introduced at the same time. This process requires precise control of reaction conditions, such as reaction temperature, proportion of reactants, etc., to ensure that the reaction proceeds in the direction of generating the target product.
Furthermore, synthesis strategies based on intramolecular rearrangement reactions can be considered. Design starting materials with specific structures, and under suitable reaction conditions, the internal rearrangement of the molecules will form the desired carbon-carbon bonds and functional group distribution. By controlling the reaction conditions, the rearrangement reaction selectively occurs to generate an intermediate containing the target functional group, and then through subsequent reactions, such as etherification of hydroxyl groups, ethoxy groups are introduced to finally obtain 2% 2C3-diethoxybutyric acid.
The above synthesis methods have their own advantages and disadvantages. It is necessary to choose an appropriate synthesis path according to the actual situation, such as the availability of raw materials, the cost of the reaction, and the purity requirements of the target product, in order to efficiently obtain 2% 2C3-diethoxybutyric acid.
What is the price range of 2,3-difluorophenylacetic acid in the market?
2% 2C3-diethylaminobutyric acid is available in the market, and its price varies depending on the quality, supply and demand. In the past, this product was available in the market, and the price may be between tens and hundreds of dollars per catty. If its quality is pure, and there are many people in the market who want it, its price will be high; if the quality is inferior, and the supply exceeds the demand, the price will drop.
In the past, there were people who were Jia, and they were in the trade of this product. They received the top grade, which was made of precision work, and sold to the rich and noble, and their price was high and favorable. There are also regular products sold to ordinary households, with flat prices and thin profits. However, the state of the market is changing rapidly, and it cannot be constant.
Recently, due to various reasons, such as the increase or decrease of production, the change of demand, and the fluctuation of its price. Or I heard that there are people who sell a catty for a hundred dollars, and there are people who exchange it for hundreds of dollars. Buyers should carefully examine its quality, make the best use of it, and decide whether it is appropriate to pay the right price.
As for the exact price, it is difficult to determine quickly. If you want to know the actual price, you must consult the merchants in the cities, or go to the market in person, visit the level of the price, observe the quality of the quality, and then get the real price.