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2,3-Difluorobenzene-1,4-Diol

2,3-Difluorobenzene-1,4-Diol

Hongda Chemical

Specifications

HS Code

390203

Chemical Formula C6H4F2O2
Molar Mass 146.09 g/mol
Appearance Solid
Melting Point 120 - 122 °C
Boiling Point 247 - 248 °C
Density 1.459 g/cm³
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in common organic solvents
Pka1 9.83
Pka2 10.54
Flash Point 114 °C

As an accredited 2,3-Difluorobenzene-1,4-Diol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2,3 - difluorobenzene - 1,4 - diol packaged in a sealed, air - tight bottle.
Storage 2,3 - difluorobenzene - 1,4 - diol should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent moisture absorption and oxidation. Store separately from oxidizing agents and incompatible substances to avoid potential chemical reactions. Ensure proper labeling for easy identification.
Shipping 2,3 - difluorobenzene - 1,4 - diol is shipped in sealed, corrosion - resistant containers. Shipment follows strict chemical safety regulations, ensuring proper packaging to prevent leakage during transportation.
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2,3-Difluorobenzene-1,4-Diol 2,3-Difluorobenzene-1,4-Diol
General Information
Historical Development
In the field of chemistry, the historical evolution of 2,3-difluorobenzene-1,4-diol is also very interesting. In the past, chemical experts worked tirelessly on the road of material exploration. At the beginning, the understanding of fluoroaromatic hydrocarbon derivatives was still shallow, but many wise people were determined to explore.
Some wise people focused on the structural modification of benzene rings, wanting to introduce fluorine atoms and hydroxyl groups to give novelty. After repeated trials, or in exquisite reaction devices, with unique reagent ratios and precise temperature control, the synthesis of 2,3-difluorobenzene-1,4-diol was gradually realized.
This process is not achieved overnight, but after years of precipitation and countless failures, it is possible to rise up and gain a gradual understanding of the properties of this material and the preparation process. Its historical development, like a shining star, shines in the long river of chemistry, paving the way for subsequent researchers.
Product Overview
Today there is a compound called 2,3-difluorobenzene-1,4-diol. It is an organic compound. If it is a white crystalline powder, it has stable properties. However, it may react when it encounters strong oxidants, strong acids, and strong bases.
This compound plays a very important role in the field of organic synthesis. It can be used as a key intermediate to prepare a variety of pharmaceuticals, pesticides, and functional materials. In pharmaceutical research and development, it may help to create new antibacterial and antiviral drugs; in pesticide development, it may lead to high-efficiency and low-toxicity insecticides and fungicides.
Preparation of this product, often with specific halogenated aromatics as the starting material, is obtained through multi-step reaction. Each step of the reaction requires precise control of the reaction conditions, such as temperature, pH, reaction time, etc., to maintain yield and purity.
In short, although 2,3-difluorobenzene-1,4-diol is a micro-chemical, it has infinite potential in many fields, and the future development can be expected.
Physical & Chemical Properties
2,3-Difluorobenzene-1,4-diol is a unique chemical substance. Its physical and chemical properties are worth studying. Looking at its physical properties, at room temperature, or in a specific color state, it has a unique melting and boiling point, which is related to the change of its phase state. Its solubility is different in various solvents, which is one of its major characteristics.
From the perspective of chemical properties, due to the presence of fluorine and hydroxyl functional groups, its activity is unique. The introduction of fluorine atoms affects the distribution of electron clouds in molecules, making its chemical activity unusual. Hydroxyl groups can cause many reactions, such as nucleophilic substitution, esterification, etc. The chemical stability of this substance also depends on the interaction between its structure and functional groups. The study of the physicochemical properties of 2,3-difluorobenzene-1,4-diol may be of significant use in the fields of chemical industry and materials, which can open up new paths and promote development.
Technical Specifications & Labeling
Today there is a product called 2,3-difluorobenzene-1,4-diol. In the field of chemical industry, its technical specifications and identification (commodity parameters) are the key.
To make this product, it is necessary to follow the precise technical specifications. The material ratio must be strict, and the reaction temperature and duration should be controlled to an appropriate degree. In this way, the pure product can be obtained and meet the established standards.
As for the identification (commodity parameters), it is related to the character, purity, impurity content, etc. of this product. The properties can be known by observation; the purity geometry is clear by analysis; the amount of impurities is known by inspection. Only by accurately marking can this product be used for various purposes, and each can do its best, without error. Technical specifications and labeling (commodity parameters), which complement each other, are the quality standards of 2,3-difluorobenzene-1,4-diol.
Preparation Method
The method of making 2,3-difluorobenzene-1,4-diol is related to the raw materials and production process, reaction steps and catalytic mechanism. First take an appropriate amount of fluoroaromatic hydrocarbons as raw materials, which is the foundation. In a special reactor, adjust to the appropriate temperature, about one hundred and twenty degrees Celsius, add alkali metal hydroxide to promote nucleophilic substitution reaction. During this time, strictly control the temperature, do not make the fluctuation too large, causing the reaction disorder.
During the reaction, a specific metal salt is used as a catalyst to accelerate the reaction process and improve the yield. After several hours, when the reaction is sufficient, the product is separated by extraction. After purification by distillation, recrystallization and other steps, pure 2,3-difluorobenzene-1,4-diol is obtained. Throughout the process, the raw materials are accurate, the temperature is suitable, the catalysis is appropriate, and the steps are closely interlocked to produce the best products.
Chemical Reactions & Modifications
In the study of modern chemistry, the study of the chemical reaction and modification of 2,3-Difluorobenzene-1,4-Diol is quite important. The change of chemistry depends on the delicacy of the reaction. To obtain the superiority of 2,3-Difluorobenzene-1,4-Diol, it is necessary to observe its reaction in detail.
Observe its reaction, choose an appropriate method to adjust it, and change its properties. If a certain agent is used to promote it, or change its corresponding environment, temperature and pressure can make 2,3-Difluorobenzene-1,4-Diol change its properties accordingly. This transition is not only for structural change, but also for its use.
Chemists should carefully study the reaction of 2,3-Difluorobenzene-1,4-Diol with the sincerity of the matter, and seek the method of modification to make this substance have better effects in various domains, either as a medicine or as a material, all depend on the good plan of reaction and modification.
Synonyms & Product Names
Today there is a thing called 2,3-difluorobenzene-1,4-diol. In the field of chemical industry, there are also many nicknames and commodity names. This substance is unique and is very critical in research and application.
Its nickname is based on its chemical structure and characteristics. Or different names are derived from the arrangement of atoms and the characteristics of functional groups. And the name of the product, the merchant gives it a unique name for its promotion and distinction.
Although the name is different, it is the same, all refer to this 2,3-difluorobenzene-1,4-diol. All kinds of names, such as stars, although each has its own appearance, they all revolve around this core substance. For our chemical researchers, only by understanding their similarities and differences can we accurately explore, so that this substance can play its maximum effectiveness in the fields of chemical engineering, medicine, and other fields, and seek the well-being of the world.
Safety & Operational Standards
2,3-Difluorobenzene-1,4-diol, chemical products are also. Its safety and operating standards are related to our research.
When operating, the first thing to do is to pay attention to the environment. It must be placed in a well-ventilated place to prevent the accumulation of harmful gases. The indoor temperature should also be controlled stably, so as not to be too high or too low, so as not to cause the material properties to change.
When using this product, be sure to clean the equipment. Wash your hands first, and use protective equipment, such as gloves, goggles, etc., to avoid touching the skin and eyes. When weighing, use a precise device and take it according to the quantity, not too much or not.
When storing, find a dry, cool place away from sources of fire. Seal in a special container to prevent it from coming into contact with air, water vapor, etc., causing its qualitative change.
If there is a spill, leave the scene quickly, do not approach it. Quickly clear it with appropriate materials and do not spread it. If you accidentally touch the body, rinse it with water quickly, and seek medical attention in serious cases.
The record of the experiment should not be ignored. Every step of operation, phenomenon and data is recorded in detail for reference.
All of these are the rules for the safety and operation of 2,3-difluorobenzene-1,4-diol. We should abide by them to ensure the safety and accuracy of research.
Application Area
2,3-Difluorobenzene-1,4-diol is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it may be a key intermediate, helping to create special drugs to treat various diseases. In the field of material science, this compound may participate in the synthesis of materials with specific properties, such as those with excellent insulation or photoelectric properties, suitable for electronic devices, etc. And in fine chemicals, it can be used as a fine chemical with raw material characteristics, contributing to the development of industry. Although it is not impressive, it is really important in various application fields. We need to explore it in depth to make the best use of it and contribute to the progress of the world.
Research & Development
I am dedicated to the research of 2,3-difluorobenzene-1,4-diol. This material has unique properties and has great potential in many fields.
At the beginning, I explored the method of its synthesis, and after repeated attempts, studying ancient books, and referring to previous methods, I found a feasible way. During the synthesis process, the reaction conditions were strictly controlled, and the temperature and reagent ratio were slightly poor, which affected the purity of the product.
Later, looking at its properties, in the field of materials science, it was found that it can improve the stability of materials and special optical properties. This discovery excites us and we know that this is a major breakthrough opportunity.
Today, although some gains have been made, it still needs to be further explored. It is hoped that in the future, it can expand its application scope, shine in the fields of medicine, electronics, etc., promote the development of this field, and bring new changes to the academic and industrial circles.
Toxicity Research
The toxicity of 2,3-Difluorobenzene-1,4-Diol is studied today. Looking at its chemical structure, fluorine and hydroxyl groups, fluorine, are active, or chemically react in organisms, disturbing the normal biochemical order. Although hydroxyl groups are common, they coexist with fluorine in this structure, and their properties are different.
Measured by various experimental methods, this substance was administered to the test organisms to observe the changes in its physiological characteristics and biochemical indicators. See low concentrations, the behavior and metabolism of the test organisms are slightly different; high concentrations show significant toxicity, such as decreased vitality and organ damage.
The reason is that this substance may enter the cell and interact with key molecules, such as proteins and nucleic acids, to change its conformation and function. Or disrupt the ion balance and enzyme activity in the cell. It can be seen that 2,3-Difluorobenzene-1,4-Diol is toxic, and its toxicological mechanism should be investigated in detail in order to protect and apply it.
Future Prospects
2,3-Difluorobenzene-1,4-diol is also a chemical that I have dedicated myself to researching. Looking to the future, it is expected to become a key raw material for new anti-cancer drugs in the field of medicine. The unique structure of this compound can precisely target cancer cells, efficiently inhibit their proliferation, and has great prospects.
In materials science, or lay the foundation for new high-performance polymers. After clever polymerization, materials with excellent thermal stability and mechanical properties are widely used in aerospace and sturdy aircraft components.
Or shine in the field of electronics, with its excellent electrical properties, it can power advanced semiconductor materials, accelerate chip operation, and improve equipment performance. I firmly believe that in time, 2,3-difluorobenzene-1,4-diol will shine and benefit mankind.
Where to Buy 2,3-Difluorobenzene-1,4-Diol in China?
As a trusted 2,3-Difluorobenzene-1,4-Diol manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,3-Difluorobenzene-1,4-Diol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,3-difluorobenzene-1,4-diol?
2% 2C3-diethylbenzene-1% 2C4-dialdehyde is one of the organic compounds. It has a wide range of uses and is of great value in many fields.
In the field of chemical synthesis, this compound is often a key intermediary. It can be converted into other more complex and versatile organic compounds through specific chemical reactions. For example, through a series of carefully designed reaction steps, it can be involved in the construction of polymer polymers with specific structures and functions. These polymers can be used in the field of materials science to make engineering plastics with excellent performance, used in automobile manufacturing, electronic equipment shells, etc., because they can give materials excellent mechanical properties and stability.
In the field of medicinal chemistry, 2% 2C3-diethylbenzene-1% 2C4-dialdehyde also has its uses. It may be used as a starting material and modified by multi-step reactions to synthesize lead compounds with specific pharmacological activities. Based on the structure of this compound, researchers can adjust its interaction with biological targets through ingenious chemical modification, and then develop new drugs for the treatment of various diseases, such as certain specific inflammation or tumors.
Furthermore, in the fragrance industry, due to its unique chemical structure, 2% 2C3-diethylbenzene-1% 2C4-dialdehyde can be used as a synthetic precursor of fragrance components. The products obtained after chemical transformation, or have unique aroma characteristics, can be used to prepare various fragrance products such as perfumes and air fresheners, adding unique fragrance to them, and enhancing the quality and attractiveness of the products.
From this perspective, although 2% 2C3-diethylbenzene-1% 2C4-dialdehyde is an organic compound, its use in chemical, pharmaceutical, fragrance and other fields is crucial, and it is of great significance to promote the development of various industries.
What are the physical properties of 2,3-difluorobenzene-1,4-diol?
The physical properties of 2% 2C3-diethyl-1% 2C4-diketone are as follows:
This substance is either liquid at room temperature, and may have a certain fluidity. Its color may be nearly colorless and transparent, and when pure, it should have no obvious variegated color. However, if it contains impurities, or there is a slight change in color. Smell it, or emit a special odor, but the odor may vary depending on the environment and purity, or it is fragrant or irritating.
Its density may be different from that of common solvents. If placed in water, it may float on the water surface or sink on the bottom according to the relationship between its density and water. And it has a specific boiling point and melting point. At the boiling point, it will change from liquid to gaseous state; when it reaches the melting point, it will melt from solid to liquid state. These two temperature characteristics are an important basis for identifying the substance.
Its solubility is also a key property. In some organic solvents, it may exhibit good solubility and can be uniformly dispersed to form a solution; in water, its solubility may vary due to molecular structural characteristics, or slightly soluble, or insoluble.
Furthermore, the viscosity of the substance is also one of the physical properties, which affects its flow characteristics in pipes and containers, and the viscosity may determine the difficulty of dumping and smearing. And its surface tension characteristics have a significant impact on the shape of droplets and the contact state with other substances.
In addition, the stability of this substance to light and heat also belongs to the category of physical properties. When heated, chemical changes such as decomposition and polymerization may occur, causing changes in its physical form and chemical composition; under light, photochemical reactions may also be initiated, affecting its stability and physical properties.
What are the chemical properties of 2,3-difluorobenzene-1,4-diol?
The chemical properties of 2% 2C3-diethyl-1% 2C4-diketone are quite unique. This substance has an active carbonyl group, and because it contains two ketone carbonyl groups, it has high chemical activity and can participate in a variety of reactions.
Nucleophilic addition is one of its common reactions. Take alcohols as an example. Under acidic or basic catalysis, the hydroxyl group of the alcohol acts as a nucleophilic agent to attack the ketone carbonyl group to generate hemi-ketal or ketal. This reaction is often used in organic synthesis to protect the carbonyl group from gratuitous reaction in subsequent reactions, and then the carbonyl group is restored by hydrolysis at a specific stage.
Oxidation reaction can occur again. Strong oxidizing agents such as potassium permanganate can oxidize it to further convert the carbonyl group into a carboxyl group or other higher valence oxygen-containing functional groups, and the product changes according to the reaction conditions. In case of mild oxidizing agents, it may only be partially oxidized to form special oxidation products, providing a different intermediate for organic synthesis.
In a basic environment, due to the electron-withdrawing effect of carbonyl groups, the compound has a certain degree of acidity in α-hydrogen, which can be taken away by bases to generate carbon negative ions. As a nucleophile, this carbon negative ion can react with electrophilic reagents such as halogenated hydrocarbons and aldosterones to construct new carbon-carbon bonds, which greatly expands its ability to construct complex structures in organic synthesis.
Condensation reaction is also an important type of reaction. For example, with active methylene-containing compounds, under alkali catalysis, condensation can occur to form products with conjugated structures, which are widely used in the synthesis of materials with special optical and electrical properties and pharmaceutical intermediates.
2% 2C3 -diethyl-1% 2C4 -dione With its diverse chemical properties, it has important value in many fields such as organic synthesis, drug research and development, and materials science, providing a key foundation for the creation of new compounds and functional materials.
What are the synthesis methods of 2,3-difluorobenzene-1,4-diol?
The synthesis method of 2% 2C3-diethyl-1% 2C4-diketone is as follows:
First, the Claisen condensation reaction can be used. Select a suitable ester compound and react under the catalytic action of a strong base. For example, taking ethyl acetate derivatives as an example, in the environment of a strong base such as sodium ethanol, the α-hydrogen atom in the ester molecule will be taken away by the base to form a carboanion. This carboanion has nucleophilic properties and can perform nucleophilic addition reactions on the esters of another molecule, and then go through a series of proton transfer, elimination and other steps to form a beta-ketoate. After hydrolysis and decarboxylation of β-ketoate, the target product 2% 2C3-diethyl-1% 2C4-diketone is finally obtained. The key to this method lies in the precise control of the reaction conditions. Factors such as the amount of strong base, reaction temperature and reaction time will affect the process of the reaction and the yield of the product.
Second, the alkylation reaction of ketones is used. First prepare ketones with suitable structures. Under basic conditions, the α-hydrogen atom of ketones will be captured by bases to form enol negative ions. Subsequently, enol negative ions undergo nucleophilic substitution reaction with halogenated hydrocarbons, and alkyl groups are introduced. Through rational design of the reaction process, two ethyl groups are introduced successively to achieve the synthesis of 2% 2C3-diethyl-1% 2C4-diketone. During this process, the selection of halogenated hydrocarbons, the type of base and the reaction solvent need to be carefully considered to ensure the smooth progress of the reaction and improve the purity and yield of the product.
Third, the strategy of combining Michael addition with subsequent reactions is adopted. Using α, β-unsaturated ketones and active methylene compounds as raw materials, under the action of basic catalysts, the carbon anions in the active methylene compounds carry out nucleophilic addition to the β-carbon atoms of α, β-unsaturated ketones to generate Michael addition products. After that, the addition products are further reacted, such as hydrolysis, oxidation and other steps, to construct the diketone structure in the target molecule, and finally synthesize 2% 2C3-diethyl-1% 2C4-dione. This approach requires precise optimization of the reaction conditions of each step to ensure the efficiency and selectivity of each step.
What is the price range of 2,3-difluorobenzene-1,4-diol in the market?
Today, there are 2,3-diethyl-1,4-diketones. What is the price of them in the market? We will try to discuss them in the style of "Tiangong Kaiwu".
This 2,3-diethyl-1,4-diketone is an organic compound. The method of its preparation may require exquisite skills and specific raw materials. In chemical industry, the uses may be different, or it is an intermediate in the synthesis of other substances, or it plays an important role in special reactions.
However, it is difficult to determine the price in the market. The change in the price is related to many ends. First, the abundance of raw materials. If the raw materials required for preparation are readily available and inexpensive, the price of the compound may not be high; on the contrary, if the raw materials are scarce and expensive, the price will rise.
Furthermore, the preparation is difficult and easy. If the preparation method is complicated, requires multiple processes, exquisite equipment and professional personnel, and requires a lot of manpower, material resources and financial resources, its price is expensive; if the preparation is easier, the cost is low and the output can be increased, the price may be close to the people.
In addition, the supply and demand of the market is also the main reason. If there are many people who want it, but there are few products, the supply is in short supply, and the price will rise; if the supply exceeds the demand, the price will be reduced in terms of sales.
In conclusion, although it is difficult to determine the exact price of 2,3-diethyl-1,4-diketone in the market, it can be concluded that its price will change due to raw materials, preparation, supply and demand, etc., or fluctuate between low prices and high prices. It is difficult to determine.