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2,3-Difluoro-1-Methoxy-4-Nitrobenzene

2,3-Difluoro-1-Methoxy-4-Nitrobenzene

Hongda Chemical

Specifications

HS Code

519236

Chemical Formula C7H5F2NO3
Molecular Weight 189.116 g/mol
Appearance Typically a solid (description may vary by purity and conditions)
Boiling Point Data may vary; needs specific experimental determination
Melting Point Data may vary; needs specific experimental determination
Density Data may vary; needs specific experimental determination
Solubility In Water Low solubility (organic nitro - fluorinated compounds generally have low water solubility)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (general for such aromatic compounds)
Vapor Pressure Low vapor pressure due to its relatively high molecular weight and polar nature
Flash Point Data may vary; needs specific experimental determination

As an accredited 2,3-Difluoro-1-Methoxy-4-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2,3 - difluoro - 1 - methoxy - 4 - nitrobenzene packaged in a sealed bottle.
Storage 2,3 - difluoro - 1 - methoxy - 4 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and strong oxidizing agents. Store in a tightly sealed container to prevent leakage and exposure to air or moisture, which could potentially affect its chemical stability.
Shipping 2,3 - difluoro - 1 - methoxy - 4 - nitrobenzene is shipped in tightly sealed, corrosion - resistant containers. Special care is taken to prevent exposure during transit, following strict hazardous chemical shipping regulations.
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2,3-Difluoro-1-Methoxy-4-Nitrobenzene 2,3-Difluoro-1-Methoxy-4-Nitrobenzene
General Information
Historical Development
In the field of chemical research, the evolution of 2,3-difluoro-1-methoxy-4-nitrobenzene has been quite impressive. In the past, chemists first got involved in the field of organic synthesis, and spared no effort in the exploration of compounds. At that time, the method of organic synthesis was still simple, and it was not easy to distinguish the quality of analytes.
After the years passed, science and technology gradually advanced, and the technology of organic synthesis became more and more exquisite. Various new agents and new machines came out, which was the opening road for the preparation of 2,3-difluoro-1-methoxy-4-nitrobenzene. In the past, the synthesis steps were cumbersome and the yield was quite low, but the researchers were determined.
In recent times, chemical theory has advanced and analytical methods have become more and more clear. 2,3-difluoro-1-methoxy-4-nitrobenzene has been widely used in medicine, agriculture and other industries, and its synthesis methods have also been innovative. The yield and purity have been greatly improved, leaving a deep impression on the development of chemistry.
Product Overview
About 2,3-difluoro-1-methoxy-4-nitrobenzene
Fu 2,3-difluoro-1-methoxy-4-nitrobenzene is a valuable compound in the field of organic synthesis. Its appearance is light yellow crystalline powder, and its properties are relatively stable at room temperature and pressure.
In this compound, fluorine atoms, methoxy groups and nitro groups are ingeniously combined, giving it unique chemical activity. Fluorine atoms have strong electronegativity, which can significantly affect the electron cloud distribution of molecules, thereby changing their physical and chemical properties. Methoxy groups adjust the electron density of the benzene ring by virtue of their electron donator effect. The nitro group, as a strong electron-absorbing group, makes the compound exhibit special reactivity in many reactions.
In the organic synthesis path, a specific halogenated aromatic hydrocarbon is often used as the starting material and carefully prepared by multi-step reaction. For example, the halogenated aromatic hydrocarbon and the fluorine-containing reagent undergo a nucleophilic substitution reaction to introduce fluorine atoms, and then the methoxy group and nitro group are connected by a suitable method, and the compound is finally obtained through a series of reactions. It has potential applications in the fields of medicinal chemistry, materials science, etc., or can be used as a key intermediate for the creation of new drug molecules, or used in the synthesis of materials with special properties.
Physical & Chemical Properties
The physicochemical properties of 2,3-difluoro-1-methoxy-4-nitrobenzene are of great importance. This substance is a colorless to pale yellow liquid, and its state is clarified by observing its properties. The boiling point is related to its gasification temperature, which is about a specific value. At this temperature, the substance changes from liquid to gaseous state, which is a key node in physical changes. Its melting point is also an important characterization. Under a specific temperature, solid and liquid states are transformed into each other.
On chemical properties, because of its fluorine, methoxy and nitro functional groups, fluorine has strong electronegativity, which makes the molecule have unique reactivity. Methoxy electrons and nitro electrons absorb electrons, and the two interact to affect its chemical reaction path. When encountering nucleophilic reagents, the nitro group is prone to nucleophilic substitution, and the electron cloud density of the benzene ring decreases due to the electron absorption of the nitro group, which is conducive to the attack of nucleophilic reagents. These physical and chemical properties are the basis for applications in chemical synthesis, material preparation and other fields, and researchers must not ignore them.
Technical Specifications & Labeling
There is a substance today called 2,3-difluoro-1-methoxy-4-nitrobenzene. In my chemical research, the technical specifications and identification (commodity parameters) of this substance are of the utmost importance.
Looking at its technical specifications, it is necessary to clarify its purity geometry and impurity content, which is related to its effectiveness in various reactions. Its physical properties, such as melting point, boiling point, density, etc., cannot be ignored, and are all factors that determine its quality.
When it comes to labeling, the name and chemical formula should be clearly marked so that those who see it can know what it is. In particular, it is necessary to indicate the dangerous characteristics. If it is toxic or corrosive, a significant warning is required to ensure the safety of the user. Only in this way can we use it properly in experiments and applications, give full play to its due effect, and ensure that everything goes smoothly.
Preparation Method
To prepare 2,3-difluoro-1-methoxy-4-nitrobenzene, the method of preparation is related to the raw materials and production process, reaction steps and catalytic mechanism.
Prepare raw materials to find suitable substrates containing fluorine, methoxy group and nitro group. Perform it in a specific reaction step, or first react the fluorine-containing reagent with the substrate, introduce fluorine atoms, precisely control the temperature, and comply with the laws of chemistry. Next, guide the methoxy group into, select the appropriate reagent and conditions, and make the reaction smooth. Add nitro groups to adjust the reaction environment to ensure that the nitro is at the right position.
The catalytic mechanism is also heavy. High-efficiency catalysts are selected to accelerate the reaction and reduce the energy barrier. Or metal catalysis, or acid-base catalysis, depending on the reaction characteristics. In this way, through precise control of each step, the product of 2,3-difluoro-1-methoxy-4-nitrobenzene can be obtained.
Chemical Reactions & Modifications
The industry of chemical industry is related to the change of all things. In the research of new substances, constant weight reaction and modification. Today there is a thing named 2,3-difluoro-1-methoxy-4-nitrobenzene. The synthesis method of its synthesis requires careful study of the reaction.
The chemical reaction is like a blend of yin and yang. It is necessary to go with its nature, control its temperature, and adjust its agent in order to obtain good results. The preparation of this compound should be based on fluoride, methoxidizer, and nitro agent to make it interact. However, the road of reaction is often not smooth, or there are by-products, or the speed is slow.
Therefore, if you want to improve it, you must first change its properties. After various explorations, suitable catalysts can be found to increase its activity, promote the speed of the reaction, and reduce the generation of by-products. Or optimize the reaction environment, such as selecting a good solvent and controlling the degree of pressure. In this way, the yield of this compound can be higher, the quality is purer, and it can meet the needs of chemical industry and promote the progress of science and technology.
Synonyms & Product Names
Today there is a thing called 2,3-difluoro-1-methoxy-4-nitrobenzene. This chemical thing has a wide range of uses in various fields. It also has other names, both of which are synonymous names and commodity names.
The name of the synonym is determined by its chemical properties and structural characteristics. Many parties call it different according to its characteristics, but they all refer to this thing. The name of the commodity is due to the needs of market circulation and commercial operation. Each merchant names it according to their own considerations. Although the names are different, they actually refer to this 2,3-difluoro-1-methoxy-4-nitrobenzene.
This chemical substance is the key to our chemical research, and exploring its synonymous name and commodity name is of great benefit to clarifying the market and deepening research.
Safety & Operational Standards
Code for safety and operation of 2,3-difluoro-1-methoxy-4-nitrobenzene
F 2,3-difluoro-1-methoxy-4-nitrobenzene is one of the chemical substances. Its unique nature is related to safety and operation standards, and it should not be careless.
#Storage rules
When placed in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent accidents. Do not store in one place with oxidants, acids, bases, etc. Because of its active chemical properties, it is easy to react with various substances and cause danger. Where to store, when there is a clear sign, clearly indicate the characteristics and precautions of this object, so that everyone knows its risks and dare not ignore it.
#The essentials of operation
When operating, be sure to wear appropriate protective equipment. Protective glasses can protect your eyes from splashes; gas masks can filter harmful gases and keep you safe for breathing; chemical protective clothing can prevent it from contacting the skin. The operation room needs to be well ventilated to allow air circulation and prevent the accumulation of harmful gases.
When using this object, the action should be slow, the method should be stable, and avoid spilling. If it is accidentally spilled, quickly cover it with inert materials such as sand and vermiculite for adsorption, and then collect it carefully and dispose of it according to regulations. Do not discard it at will to avoid polluting the environment.
During the experiment, strictly follow the established procedures, and do not change the steps or increase the loss dose without authorization. In case of abnormalities, such as fever, discoloration, odor, etc., immediately stop the operation, quickly evacuate the scene, and report to professionals for disposal.
In short, the safety and operation specifications of 2,3-difluoro-1-methoxy-4-nitrobenzene should be kept in mind at all times, and everything should be followed to ensure safety.
Application Area
Today, there is a thing called 2,3-difluoro-1-methoxy-4-nitrobenzene, which is quite wonderful in various application fields.
In the field of pharmaceutical development, this compound may be the key raw material for the creation of new drugs. Its unique chemical structure can be precisely matched with specific targets in organisms, helping to develop specific drugs for specific diseases and opening up new ways for the treatment of diseases.
In the field of materials science, it can also be used. Because of its special chemical properties, or can be used to prepare functional materials, such as materials with unique optical and electrical properties, it contributes to the development of electronic devices, optical instruments and other fields.
Furthermore, in the field of organic synthesis, it is often used as an important intermediate. Through a series of chemical reactions, many organic compounds with complex structures and diverse functions can be derived, promoting the progress of organic synthetic chemistry and expanding the variety and application of organic compounds.
Research & Development
The research and development of 2,3-difluoro-1-methoxy-4-nitrobenzene
In recent years, I have focused on the study of chemical substances, focusing on 2,3-difluoro-1-methoxy-4-nitrobenzene. This compound has unique properties and has great potential in many fields.
Initially involved in this substance, its molecular structure was carefully observed, and the state of atomic bonding was carefully investigated. The combination of fluorine, methoxy and nitro gives special chemical activity. In order to explore its reaction law, various experiments were set up. Test with different reagents and conditions to observe the reaction process and products.
In the process of research, difficulties are frequent. The precise control of the reaction conditions is very difficult. The temperature and pressure are slightly different, and the products may be very different. However, I did not give up, and repeatedly debugged, and finally obtained a better reaction path.
Looking forward to its development, in the field of pharmaceutical synthesis, it is expected to become a key intermediate and assist in the creation of new drugs. In terms of materials science, it may provide new opportunities for the research and development of materials with special properties. I will continue to study it, hoping to expand the world for its development.
Toxicity Research
A highly toxic substance has been studied in modern times, with the name 2,3-difluoro-1-methoxy-4-nitrobenzene. Its strong nature, in the human body and the surrounding environment, all hidden dangers.
Study its toxicity, need to be cautious. Looking at the structure of its molecules, fluorine, nitro and other groups are highly active, or easy to react with other substances, messing with the normal order of living things. Take white mice as an experiment, and small agents touch it, showing that it is restless and physiologically incompatible. Exposed to the environment containing this substance for a long time, the fur loses its luster and the organs are damaged.
And this substance is difficult to degrade in the environment, accumulates in water and soil, or enters the food chain, causing harm to all living things. Therefore, the 2,3-difluoro-1-methoxy-4-nitrobenzene is studied for its harm, so as to prevent micro-destruction, protect the well-being of all beings, and keep the environment clean.
Future Prospects
There is now a thing named 2,3-difluoro-1-methoxy-4-nitrobenzene. We have studied it chemically to see its future development, and we hope to have extraordinary changes in our hearts.
The nature of this thing is quite wonderful. The quality of chemistry may be used in various new ways. In the field of medicine, I hope to be able to assist in the research of new drugs and solve the pain of the world; in the field of materials, I hope to create strange materials and meet the needs of the times.
Looking at the future, science and technology are changing with each passing day, and the way to study this thing must be improved. It can improve its production, increase its quality, and reduce its consumption. The lower the cost, the higher the effectiveness. And the pursuit of environmental protection is urgent, and researchers should also think about how to make it without harming the environment and achieve sustainability.
Although the road ahead is long, we researchers are eager and determined to move forward. With wisdom and diligence, we hope to open up a new environment of 2,3-difluoro-1-methoxy-4-nitrobenzene, which will open up endless possibilities for future generations and live up to the demands of the times.
Where to Buy 2,3-Difluoro-1-Methoxy-4-Nitrobenzene in China?
As a trusted 2,3-Difluoro-1-Methoxy-4-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,3-Difluoro-1-Methoxy-4-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,3-difluoro-1-methoxy-4-nitrobenzene?
2% 2C3-diene-1-methoxy-4-pyridylbenzene is a crucial compound in the field of organic synthesis. It has a wide range of uses and has significant applications in pharmaceutical chemistry, materials science and many other fields.
In the field of pharmaceutical chemistry, this compound can be used as a key intermediate for the synthesis of drug molecules with specific biological activities. The structure of pyridyl and phenyl rings gives it unique electronic properties and spatial configuration, which can achieve precise binding to specific targets in organisms. For example, through appropriate chemical modification, it can exhibit high affinity and selectivity for certain disease-related enzymes or receptors, and then exert therapeutic effects. For specific types of tumor cells, modified drugs containing this structure may specifically inhibit the proliferation and metastasis of tumor cells, opening up new avenues for the development of anti-cancer drugs.
In the field of materials science, due to its conjugated structure and electronic properties, 2% 2C3-diene-1-methoxy-4-pyridylbenzene can be used to prepare organic optoelectronic materials. In organic Light Emitting Diode (OLED), it may be used as a light-emitting layer material. With its unique electronic transition characteristics, it can achieve an efficient electroluminescence process and improve the luminous efficiency and color purity of OLED devices. In the field of organic solar cells, this compound may also be applied to active layer materials to enhance light absorption and charge transport, thereby improving the photoelectric conversion efficiency of solar cells.
In short, 2% 2C3-diene-1-methoxy-4-pyridylbenzene has great potential in the fields of drug development and material preparation due to its unique chemical structure. With the continuous deepening of research, it is expected to lead to more innovative applications and results.
What are the physical properties of 2,3-difluoro-1-methoxy-4-nitrobenzene?
2% 2C3-diene-1-methoxy-4-carbonylbenzene, this substance is an organic compound with unique physical properties. In terms of its properties, it is mostly a crystalline solid under normal conditions. Due to its intermolecular forces and orderly arrangement, it has a regular crystal structure and high stability.
The melting point is also an important property, usually in a specific temperature range, which is affected by the compactness of the molecular structure, the type of intermolecular forces and the strength. The melting point is high when the intermolecular forces are strong and the structure is tight; otherwise, it is low. The specific melting point value is of great significance for the identification and purity judgment of the compound.
In terms of solubility, the solubility of this compound in organic solvents varies significantly. In common organic solvents such as ethanol, acetone, and chloroform, due to the interaction between molecules and solvent molecules, there is a certain solubility, which can be dissolved and dispersed, which is conducive to chemical reactions, separation, purification, and analysis and detection; in water, due to the mismatch between molecular polarity and water molecules, the solubility is poor. Due to the strong hydrogen bond between water molecules, the compound is difficult to form an effective interaction with water, so it is difficult to dissolve.
Volatility, due to its intermolecular force and relative molecular weight, volatility is low. Relative molecular weight is large and intermolecular force is strong, so it takes more energy for molecules to break away from the liquid surface and enter the gas phase, so it is not easy to volatilize and has good stability during storage and use.
Density is also one of the characteristics. The density of this compound is different from that of common organic solvents and water, which is crucial in operations involving separation, extraction and phase equilibrium research of mixed systems. It can be used for phase separation and enrichment according to density differences, providing an important basis for chemical production and chemical research.
The above physical properties are of great significance for the synthesis, separation, purification and application of 2% 2C3-diene-1-methoxy-4-carbonylbenzene, laying the foundation for related chemical research and industrial production.
What are the synthesis methods of 2,3-difluoro-1-methoxy-4-nitrobenzene?
The synthesis method of 2% 2C3-diene-1-methoxy-4-cyanobenzene covers the chemical synthesis method, which is often based on its molecular structure and the existing reaction principle.
First, it can be obtained by the conversion of functional groups of compounds with similar structures. If a compound containing a benzene ring is used as the starting material, if the benzene ring already has appropriate substituents, methoxy can be introduced by nucleophilic substitution reaction. Nucleophilic substitution is a reaction in which the nucleophilic test agent attacks positively charged or partially positively charged atoms, causing old bonds to break and new bonds to form. Here, an appropriate alkoxide can be selected as a nucleophile to react with benzene derivatives containing halogen atoms, so that the halogen atoms are replaced by methoxy groups.
As for the introduction of cyanyl groups, it can be achieved by the reaction of halogenated aromatics with cyanide reagents. Common cyanide reagents such as potassium cyanide, sodium cyanide, etc. Under appropriate reaction conditions, halogen atoms can be replaced by cyanide groups to obtain cyanide-containing products. This reaction requires attention to the control of reaction conditions, such as temperature, solvent, etc., to ensure the smooth progress of the reaction and the purity of the product.
Second, the strategy of constructing benzene rings can also be used. For example, through a multi-step reaction, a chain compound with a specific substitution mode is first synthesized, and then a benzene ring structure is formed through a cyclization reaction. In the synthesis of chain compounds, carbon-carbon bond formation reactions can be used, such as the Grignard reaction. Grignard reagents are organomagnesium compounds, which react with halogenated hydrocarbons, carbonyl compounds, etc., to effectively construct carbon-carbon bonds. By ingeniously designing the reaction steps, the substituents on the chain compounds are in the right position, and then cyclization reactions, such as nucleophilic substitution or elimination reactions in molecules, close the loop to form a benzene ring, and in subsequent steps, methoxy groups and cyanos are introduced in sequence.
Or metal-catalyzed reactions can be considered. Today, metal catalysis is widely used in organic synthesis. For example, the cross-coupling reaction catalyzed by palladium can precisely connect different organic fragments. Using the organic fragment containing methoxy group and cyano group as raw materials, cross-coupling with benzene ring derivatives occurs through the action of palladium catalyst, and the structure of the target molecule is constructed in one step. This method has the advantages of high efficiency and good selectivity, but it also requires high reaction conditions and catalysts. It is necessary to precisely adjust the reaction parameters to obtain the ideal yield and selectivity.
What are the precautions for storing and transporting 2,3-difluoro-1-methoxy-4-nitrobenzene?
2% 2C3-diene-1-methoxy-4-pyridylbenzene is an extremely rare and unique chemical. When storing and transporting, many key considerations must not be ignored.
First, when storing, make sure that the environmental conditions are suitable. Due to its nature, it may be quite sensitive to temperature, so it needs to be stored in a cool place to avoid high temperature deterioration or dangerous reactions. The ideal storage temperature should be maintained within a certain range, such as [X] degrees Celsius. At the same time, the humidity should not be underestimated. Excessive humidity may cause the substance to absorb moisture, which affects its purity and stability. Therefore, it should be stored in a dry place, and the environment can be maintained dry with the help of desiccants.
Second, the packaging must be tight. This substance may react with air, moisture, etc., so a packaging material with good sealing performance is required. If a special sealed container is used, ensure that there is no gap to prevent the intrusion of external substances. And the packaging material itself should not chemically react with the chemical substance to avoid damage to the substance or unsafe factors.
Third, during transportation, shock-proof measures are indispensable. The substance may change its internal structure due to vibration, which in turn affects its chemical properties. A buffer device should be installed in the transportation vehicle to avoid severe bumps and collisions. In addition, the transportation route should also be carefully planned, and it should be kept away from densely populated areas and dangerous areas such as high temperature and fire sources to prevent serious consequences in the event of accidents.
Fourth, whether it is storage or transportation, it is necessary to strictly follow relevant safety regulations and standards. Operators must be professionally trained, familiar with the characteristics and safe operation procedures of the substance, and equipped with appropriate protective equipment, such as protective gloves, goggles, etc., to ensure their own safety. The whole process of storage and transportation should also be recorded in detail for traceability and inspection. In this way, the substance can be properly stored and transported to ensure its safety and stability.
What is the market price range for 2,3-difluoro-1-methoxy-4-nitrobenzene?
I don't know the market price range of "2,3-diene-1-methoxy-4-pyridylnaphthalene". This is a very professional and specific chemical substance, and its price is influenced by many factors.
First, the purity has a great impact. If the purity is extremely high and almost perfect, it can be used for high-end scientific research experiments, and the price is high; if the purity is slightly lower, it is only for general basic research or industrial preliminary applications, and the price is slightly reduced.
Second, the ease of preparation is also critical. If its preparation requires complex processes, rare raw materials and harsh reaction conditions, the cost will increase greatly and the price will be high. If the preparation process is relatively simple, the cost is controllable, and the price is close to the people.
Third, the market supply and demand relationship is an important factor. If many scientific research institutions and enterprises have strong demand for it, but the supply is limited, the price will soar; if the demand is low and the supply is sufficient, the price will drop.
Fourth, the difference between manufacturers also leads to price differences. Well-known large factories pay attention to quality and reputation, and the quality of their products is excellent, but the price may be high; small factories produce, the price may be low, but the quality may be different.
To sum up, in order to know the exact market price range, it is necessary to check the chemical product trading platform in detail, consult professional chemical suppliers, or obtain information in relevant industry exchanges.