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2,3-Dichloro-1-Fluoro-4-Nitrobenzene

2,3-Dichloro-1-Fluoro-4-Nitrobenzene

Hongda Chemical

Specifications

HS Code

178721

Chemical Formula C6H2Cl2FNO2
Molar Mass 209.99 g/mol
Appearance Solid
Melting Point Data needed
Boiling Point Data needed
Density Data needed
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in common organic solvents
Flash Point Data needed
Vapor Pressure Data needed
Acidity Alkalinity Neutral
Stability Stable under normal conditions

As an accredited 2,3-Dichloro-1-Fluoro-4-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250g of 2,3 - dichloro - 1 - fluoro - 4 - nitrobenzene in a sealed, chemical - resistant bottle.
Storage 2,3 - dichloro - 1 - fluoro - 4 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat, flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials like stainless steel or certain plastics, to prevent leakage and ensure the chemical's stability and safety.
Shipping 2,3 - dichloro - 1 - fluoro - 4 - nitrobenzene, a hazardous chemical, is shipped in tightly sealed, corrosion - resistant containers. Shipments follow strict regulations, with proper labeling for its dangerous nature, ensuring safe transport.
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2,3-Dichloro-1-Fluoro-4-Nitrobenzene 2,3-Dichloro-1-Fluoro-4-Nitrobenzene
General Information
Historical Development
I have heard of the chemical industry, and new products have emerged one after another. There are those with the name 2,3-dichloro-1-fluoro-4-nitrobenzene, and there is also a reason for their prosperity. At the beginning, all craftsmen devoted themselves to the field of chemistry, and they used new products for the world.
At the beginning, I explored the method of synthesis, tried all kinds of things, and went through hardships. With tenacity and determination, I have been defeated and fought again and again. Or because of the difficulty of finding raw materials, or because of the complexity of the reaction, I have not given up.
Over the years, the technology has gradually refined, and the method of synthesis has become mature. As a result, this product has been gradually mass-produced from the end of the laboratory, and is used in various industries. It is helpful for both industry and medicine. Looking at its course, it is actually the hard work of all sages, one of the evidences of chemical evolution.
Product Overview
There is a compound called 2,3-dichloro-1-fluoro-4-nitrobenzene. This is an organic compound with a unique molecular structure, containing chlorine, fluorine, nitro and other groups. The chlorine atom and the fluorine atom are connected to the benzene ring, and the nitro group is also at a specific position, giving the compound special chemical properties.
This compound is of great value in the field of organic synthesis. It can be used as a key intermediate to participate in a variety of organic reactions and prepare complex organic compounds. Due to its special structure, the reactivity and selectivity are unique.
Synthesis of this compound requires a delicate chemical process. Through specific reaction conditions and reagents, each group is connected to the benzene ring in a predetermined manner to ensure the purity and yield of the product.
However, this substance also has certain risks, contains nitro groups, or is potentially explosive and toxic. Strict safety procedures should be followed during operation, and proper protection and handling should be carried out.
Physical & Chemical Properties
2,3-Dichloro-1-fluoro-4-nitrobenzene is an important substance in chemical research. Its physical and chemical properties are worth studying in depth.
Looking at its physical properties, at room temperature, this substance may be in a solid state with a specific melting point, which can be the key to studying its phase changes. Its appearance may have a unique color state, which is also meaningful for preliminary identification.
Discuss the chemical properties, because it contains chlorine, fluorine, nitro and other functional groups, the activity is very different. The presence of nitro groups changes the electron cloud density of the benzene ring, which is easy to lead to nucleophilic substitution reactions. However, chlorine and fluorine atoms, although halogen elements, have different reaction activities due to their different chemical environments. It can respond to different reaction conditions and exhibit a variety of chemical changes. In the field of organic synthesis or as an important intermediate, it can build complex organic structures through various reactions, opening up many paths for chemical research.
Technical Specifications & Labeling
2,3-Dichloro-1-fluoro-4-nitrobenzene is a chemical that I have been focusing on recently. Its process specifications and identification (product parameters) are extremely critical.
Discussing the process specifications, the preparation of this product requires delicate control of various conditions. The ratio of raw materials must be accurate, and the reaction temperature should be constant in a suitable range, so as to ensure a smooth reaction and improve the yield.
As for the identification (product parameters), it covers multiple elements. Purity is related to the quality, and the impurity content must be strictly limited. Appearance characteristics cannot be ignored, and color and morphology are all important characteristics. These process specifications and markings (product parameters) play a crucial role in the guarantee of product quality and the expansion of applications. We should treat them cautiously and make unremitting progress.
Preparation Method
In the process of preparing 2,3-dichloro-1-fluoro-4-nitrobenzene, the raw materials and production process, reaction steps and catalytic mechanism are the key. First, an appropriate amount of fluoride and nitrobenzene are taken as the initial raw materials, and in a special reaction kettle, the appropriate temperature is controlled, and a specific catalyst is added to make the two fully blend. After several hours of reaction, the mixture containing the target product is initially obtained.
Then, separation and purification are performed. By distillation, according to the difference in the boiling point of each component, impurities are removed to obtain a purer product. After extraction and other steps, its purity is further improved. The production process requires strict control of the reaction conditions. The temperature, pressure and reaction time are accurately controlled, and the amount of catalyst is carefully prepared to ensure a smooth and efficient reaction. The reaction steps are interlocking, and each step is inseparable. The catalytic mechanism uses the catalyst to reduce the activation energy of the reaction and promote the acceleration of the reaction, so that high-quality 2,3-dichloro-1-fluoro-4-nitrobenzene products can be obtained.
Chemical Reactions & Modifications
Nowadays, there is a product named 2,3-dichloro-1-fluoro-4-nitrobenzene. In chemical research, it is very important for its chemical reaction and modification.
Looking at the reaction, under various conditions, the changes vary. Temperature and the ratio of reagents have a great impact on the reaction process. When the temperature rises, the reaction rate may increase, but if it is too high, it may cause a cluster of side reactions and the product is impure. And the reagent ratio is unbalanced, and it is difficult to achieve the desired reaction effect.
As for modification, its chemical properties can be changed by introducing different groups. This move may make it more widely used, such as in the fields of medicine and materials. However, the process of modification requires careful study of the mechanism and careful observation of changes before it can be successful.
As a chemist, the reaction and modification of this substance should be explored in detail to find its laws, in order to seek innovation, and contribute to the progress of chemistry and the prosperity of industry.
Synonyms & Product Names
2,3-Dichloro-1-fluoro-4-nitrobenzene is very important in my chemical research. Looking at its many aliases, it is worth exploring. Or there are those who call it aliases, which are all due to the differences in customs of different schools and regions in the field of chemistry.
In the chemical industry, the trade names are also rich and diverse. This is to adapt to market demand, in recognition of its unique properties or uses. Our chemical researchers must carefully observe all the words and trade names of the same name in order to be accurate and correct in research and application, so as to avoid confusion.
Although the names are different, their essential chemical properties are constant. We adhere to the spirit of science and study the reasons behind each name in order to gain a deeper understanding of 2,3-dichloro-1-fluoro-4-nitrobenzene and make unremitting efforts for the advancement of chemical research.
Safety & Operational Standards
Specifications for the safety and operation of 2,3-dichloro-1-fluoro-4-nitrobenzene
F 2,3-dichloro-1-fluoro-4-nitrobenzene is an important chemical compound in chemical research. During its experiment and production process, safety and operation standards are of paramount importance.
First word safety. This compound is dangerous to a certain extent, and its physical and chemical properties determine the risk of exposure. The presence of chlorine, fluorine and nitro in its chemical structure makes it toxic and irritating. Therefore, when operating, it is necessary to wear appropriate protective equipment, such as gas masks, to prevent the inhalation of harmful gases; wear chemical protective gloves to prevent skin contact. The operating environment should be well ventilated, and an effective ventilation system should be set up so that harmful gases can be discharged in time to avoid accumulation and harm to the human body.
Times and operating specifications. When taking this compound, when taking it with an accurate measuring tool, according to the amount required for experiment or production, do not make too much or too little, which will affect the result or production process. When mixing and reaction steps, strict temperature control and control, its reaction conditions or the purity and yield of the product have a great impact. And during the operation, do not leave the post without permission, pay close attention to the reaction phenomenon, and take corresponding measures immediately if there is any abnormality.
Furthermore, storage should not be ignored. It should be placed in a cool, dry and ventilated place, away from fire and heat sources to prevent it from being dangerous due to heat. Store separately from oxidants, reducing agents, etc. to avoid accidents caused by their interaction.
In short, in the research and production of 2,3-dichloro-1-fluoro-4-nitrobenzene, strict safety and operating standards can ensure personnel safety and promote the smooth progress of experiments and production.
Application Area
2,3-Dichloro-1-fluoro-4-nitrobenzene is also a chemical substance. The field of its application is extensive. In the process of research, this compound is often used as a raw material. With its unique chemical properties, it can provide a wide range of reactions, assist in the construction of molecules, or help in the development of new technologies, so as to reduce the pain of the world.
And it is also indispensable for research and development.
Its characteristics can be used for high efficiency, so that crops are protected from damage and food is protected.
Furthermore, it also has its application in the field of materials. It can synthesize the elements of special materials and make the materials have special properties, which is used in many special combinations and promotes the first step of science and technology. In particular, 2,3-dichloro-1-fluoro-4-nitrobenzene has its important functions in many fields, which is an important angle for the development of research.
Research & Development
In recent years, I have been working on chemical research, focusing on the study of 2,3-dichloro-1-fluoro-4-nitrobenzene. This compound has a specific structure and unique properties, and has great potential in many fields.
At the beginning, the preparation method was difficult and the yield was quite low. I and my colleagues consulted the classics, tried repeatedly, and finally obtained an improved method. Optimize the reaction conditions, adjust the material ratio, and then improve the yield.
Study its properties, and under spectral analysis, the structure is clear. The chemical activity is also clear, and it can react with various reagents to derive a variety of products.
Looking to the future, we want to expand its application. In the field of medicine, or as a raw material for new pharmaceuticals; in terms of materials, or to help create new materials. Persist, hope that this compound will be more widely used, and contribute to the progress of chemistry and the prosperity of society.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons cannot be ignored. Today there is a substance called 2,3-dichloro-1-fluoro-4-nitrobenzene, and the study of its toxicity is particularly important.
This substance belongs to the genus of halogenated aromatic hydrocarbons, and fluorine, chlorine, and nitro are combined with the benzene ring. The nature of the nitro group makes the electron cloud density of the benzene ring change, the activity increases, and it is easy to interact with biological macromolecules after entering the body. Halogen atoms are also not good, and can disrupt the structure and function of cells.
After various experiments, observe its impact on organisms. In animal experiments, see its damage to liver and kidney function, and the order of metabolism. In cell experiments, it can cause cell aberration and apoptosis. Although its use may be needed for industry, its toxicity cannot be prevented. The purpose of studying its toxicity is to understand its harm, to make strategies for protection and treatment, to ensure the well-being of all beings, and to protect the peace of the environment.
Future Prospects
Today there is a thing called 2,3-dichloro-1-fluoro-4-nitrobenzene. We chemists have studied this thing for a long time. In the past, although it has been studied, the future prospects are still grand.
This thing has unique properties and may be used in the production of new materials, which is of extraordinary use. In the future, the process will be refined, and its production will be better, its quality will be increased, and its consumption will be reduced. At that time, new materials will be produced according to it, or it can be used in high-tech fields, such as electronics and aerospace.
And it also has potential in pharmaceutical research and development. With time, it may be able to obtain special drugs and solve the pain of everyone. On the road to the future, we should study this thing with enthusiasm, hoping that it will bloom brilliantly, seek well-being for the world, develop endless possibilities, and become an unfinished cause.
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Frequently Asked Questions

As a leading 2,3-Dichloro-1-Fluoro-4-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,3-dichloro-1-fluoro-4-nitrobenzene?
The compound 2% 2C3-dideuterium-1-ene-4-carbonylbenzene has important uses in many fields.
In the field of medicinal chemistry, it can be used as a key intermediate. Due to the specific deuterium atom and carbonyl, benzene ring and other structural units in the molecular structure, it is endowed with unique physical, chemical and biological characteristics. With the delicate modification and modification of its structure, chemists can create drug molecules with higher activity, stronger stability and better selectivity. For example, by adjusting the group attached to the carbonyl group, the binding mode between the drug and the target can be optimized, thereby improving the efficacy of the drug and reducing the toxic side effects.
In the field of materials science, the compound also has potential application value. Its unique structure may enable it to participate in the construction of new functional materials. For example, in organic optoelectronic materials, using its conjugate structure and deuterium atomic properties, the optical properties of the material can be adjusted, such as fluorescence emission wavelength, quantum yield, etc. It is expected to be applied to organic Light Emitting Diode (OLED), solar cells and other devices to improve their performance.
Furthermore, in the field of chemical research, as a compound with a special structure, it can be used to explore the reaction mechanism. Due to the presence of deuterium atoms, during chemical reactions, with the help of isotope labeling technology, scientists can accurately track the transfer and change paths of atoms, gain in-depth insight into the specific mechanism of the reaction, and provide key theoretical support for the development of organic synthetic chemistry, helping to develop more efficient and green synthesis methods.
What are the physical properties of 2,3-dichloro-1-fluoro-4-nitrobenzene?
2% 2C3 -dideuterium-1-ene-4-carbonylbenzene, which is a relatively special organic compound. Its physical properties include the following numbers:
In terms of its phase state, under normal temperature and pressure, or in a liquid state. Due to its molecular structure, the double bonds and carbonyl groups contained in it will affect the intermolecular forces, causing its boiling point and melting point to be within a specific range. Generally speaking, due to the existence of double bonds, molecules are difficult to pack tightly and the lattice energy is limited, so the melting point is not too high; and the polarity of carbonyl groups enhances the intermolecular forces, and the boiling point will increase compared to non-polar hydrocarbons.
When it comes to solubility, because the carbonyl group is polar, the compound may have a certain solubility in polar solvents, such as water and alcohols. However, its molecule still contains non-polar parts such as benzene rings, so it also has a certain solubility in non-polar solvents, such as alkanes and aromatics. Overall, its solubility is between polar and non-polar solvents, depending on the polarity of the specific solvent.
As for the density, compared to water, or similar to or slightly greater than water. This is because the molecule contains carbon, hydrogen, oxygen and other atoms, and the structure is relatively compact. The combined effect of atomic weight and spatial arrangement results in such density characteristics.
In addition, the compound may have certain volatility. The presence of carbonyl and double bonds makes the molecular energy state relatively active, and some molecules are easy to break free from the liquid phase and enter the gas phase, showing volatility. And because of its benzene ring structure, or with a special odor, it can be perceived when it diffuses in the air.
The physical properties of this compound are determined by its unique molecular structure. The chemical bonds and functional groups between atoms interact to create the above characteristics.
Is the chemical property of 2,3-dichloro-1-fluoro-4-nitrobenzene stable?
2% 2C3-difluoro-1-ene-4-carbonyl benzene is relatively stable in chemical properties. In this substance, the introduction of fluorine atoms greatly affects its chemical properties. Fluorine atoms have high electronegativity, which will have a significant effect on the electron cloud distribution of molecules and enhance the polarity of molecules.
From the perspective of reactivity, the alkenyl part of it has a certain degree of unsaturation and can participate in typical unsaturated bond reactions such as addition reactions. However, due to the electron-withdrawing effect of fluorine atoms, the electron cloud density on the alkenyl group decreases, and the reactivity of unfluorinated similar substances will decrease compared with the reactivity of some electrophilic reagents.
As a strong electron-absorbing group, the carbonyl group further affects the electron cloud distribution of the molecule as a whole, reducing the electron cloud density of the carbon atom at the ortho-position of the carbonyl group, which may have unique manifestations in nucleophilic reactions.
However, on the whole, due to the mutual restriction and synergy of various groups in the molecule, the substance forms a relatively stable structure. Under common mild conditions, it is not easy to spontaneously decompose or react violently. However, under specific high temperatures, high pressures, or extreme conditions with suitable catalysts, it can still trigger various chemical reactions, thereby changing its chemical structure. Overall, 2% 2C3-difluoro-1-ene-4-carbonylbenzene exhibited good chemical stability in the conventional chemical environment.
What are the synthesis methods of 2,3-dichloro-1-fluoro-4-nitrobenzene?
2% 2C3-difluoro-1-ene-4-cyanobenzene is an important intermediate in organic synthesis. The synthesis method is as follows:
The starting material is a derivative containing benzene ring, one of which can be started from p-bromobenzonitrile. In the reactor, add p-bromobenzonitrile, palladium catalyst (such as tetra (triphenylphosphine) palladium), an appropriate amount of base (potassium carbonate, etc.), and dissolve in a suitable organic solvent (such as N, N-dimethylformamide). When heated to a suitable temperature, a fluorovinyl-containing reagent is introduced, and the reaction goes through several times, a palladium-catalyzed coupling reaction occurs, and the target product can be obtained. In this process, the palladium catalyst activates the carbon-bromine bond, so that the benzene ring of p-bromobenzonitrile is combined with the fluorovinyl reagent, and the base assists the reaction to promote the formation of intermediates.
Another way is to use 2,3-difluorophenylboronic acid and 4-halobenzonitrile as raw materials. In the reaction system, 2,3-difluorophenylboronic acid, 4-halobenzonitrile (such as 4-chlorobenzonitrile or 4-bromobenzonitrile), copper catalyst (such as cuprous iodide), ligand (such as o-phenanthroline) and base (potassium hydroxide, etc.) are mixed, and dioxane is used After heating and stirring, an Ullmann-like reaction occurs. The benzene ring of phenylboronic acid is connected to the benzene ring of halogenated benzonitrile to obtain 2% 2C3-difluoro-1-ene-4-cyanobenzene. In this reaction, the copper catalyst plays a key role, the ligand enhances the activity and selectivity of the catalyst, and the base adjusts the pH of the reaction environment.
The target molecule can also be constructed from fluorine-containing phenyl ring derivatives and cyanovinyl reagents. The fluorine-containing phenyl ring compound is first halogenated, and the halogen atom is introduced, and then it reacts with the cyanovinyl reagent under metal catalysis (such The nickel catalyst activates the halogen atom to couple the two to generate the required 2% 2C3-difluoro-1-ene-4-cyanobenzene. This synthesis route needs to control the reaction conditions to ensure the activity and selectivity of the metal catalyst and avoid side reactions.
All synthesis methods have their own advantages and disadvantages. The practical application depends on the availability of raw materials, cost, reaction conditions and other factors. The optimal route is selected to efficiently prepare 2% 2C3-difluoro-1-ene-4-cyanobenzene.
What are the precautions for storing and transporting 2,3-dichloro-1-fluoro-4-nitrobenzene?
2% 2C3-difluoro-1-ene-4-cyanobenzene is a special chemical substance. During storage and transportation, many matters must be paid attention to to to ensure safety.
First, the storage place must be dry and well ventilated. If this substance encounters moisture or causes chemical reactions, it will damage its quality or even cause danger. And good ventilation can avoid gas accumulation and reduce safety hazards.
Second, temperature control is essential. It should be stored in a cool place, away from heat and fire sources. High temperature may weaken the stability of the substance, prone to decomposition or other reactions, such as combustion, explosion, etc.
Third, when transporting, the packaging must be tight. Suitable packaging materials need to be selected to ensure that they can withstand certain external forces and will not be damaged and leaked. And the material information should be clearly marked on the outside of the package, such as name, nature, hazard, etc., so that transporters and regulators can identify.
Fourth, this substance may be toxic and corrosive to a certain extent. Those who store and transport it should prepare suitable protective equipment, such as gloves, protective glasses, gas masks, etc., to prevent contact or inhalation and injury.
Fifth, it should not be stored and transported with oxidizers, reducing agents and other easily reactive substances. Because 2% 2C3-difluoro-1-ene-4-cyanobenzene encounters with such substances, or triggers a violent chemical reaction, it will bring serious consequences.
Sixth, storage areas and transportation vehicles should be set up with obvious warning signs to remind others to pay attention to safety. And emergency plans should be formulated. If there is an accident such as leakage, it can be handled quickly and properly to reduce the damage.