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2,3,5-Trifluorobenzeneacetonitrile

2,3,5-Trifluorobenzeneacetonitrile

Hongda Chemical

Specifications

HS Code

568543

Chemical Formula C8H3F3N
Molar Mass 171.11 g/mol
Appearance colorless liquid
Boiling Point 195 - 196 °C
Density 1.297 g/mL at 25 °C
Flash Point 82 °C
Solubility In Water Insoluble
Refractive Index 1.437 at 20 °C

As an accredited 2,3,5-Trifluorobenzeneacetonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2,3,5 - trifluorobenzeneacetonitrile packaged in a sealed, chemical - resistant bottle.
Storage 2,3,5 - trifluorobenzeneacetonitrile should be stored in a cool, dry, well - ventilated area, away from sources of heat and ignition. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, acids, and bases to avoid potential reactions. Ensure the storage location is out of reach of unauthorized personnel.
Shipping 2,3,5 - trifluorobenzeneacetonitrile is shipped in accordance with strict chemical transport regulations. It's packaged in specialized containers to prevent leakage, and transported under controlled conditions to ensure safety during transit.
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2,3,5-Trifluorobenzeneacetonitrile 2,3,5-Trifluorobenzeneacetonitrile
General Information
Historical Development
In the mid-20th century, the exploration of fluorinated compounds in the field of organic chemistry was in the ascendant. At that time, many chemists devoted themselves to the creation and research of new fluorinated organic compounds. The compound "2,3,5 - Trifluorobenzeneacetonitrile" also came to the fore during this period.
At first, it was difficult to synthesize this compound, the reaction conditions were harsh, and the yield was extremely low. However, with perseverance, chemists repeatedly studied and improved. Over time, new technologies and methods emerged. From the initial exploration and experimentation to gradually mastering the key reaction steps, the understanding of the reaction mechanism became more and more in-depth.
In the later stage, the reaction conditions were optimized and the yield was significantly improved. This compound has gradually shown potential in the fields of materials science and drug development, opening a new chapter of application. Its development process is a vivid portrayal of the continuous progress of chemical research.
Product Overview
Description of 2,3,5-trifluorophenylacetonitrile
There is now a product called 2,3,5-trifluorophenylacetonitrile. It is a key raw material for organic synthesis and has important uses in medicine, pesticides and other fields.
Looking at its shape, under room temperature and pressure, it is a colorless to light yellow transparent liquid with pure quality and stable properties. Smell it, it has a specific smell, but its taste is not pungent or intolerable.
In terms of its properties, it has certain chemical activity. Because it contains cyanide groups and fluorine atoms, it can participate in many chemical reactions. The presence of cyanyl groups allows them to be converted into important intermediates such as carboxylic acids and amines through reactions such as hydrolysis and reduction; the introduction of fluorine atoms greatly changes the electron cloud distribution of molecules and enhances the fat solubility and stability of compounds. In the field of drug research and development, this property can often improve the biological activity and metabolic stability of drugs.
From the perspective of synthesis, it is often prepared through specific fluorination and cyanidation reactions. The synthesis process requires precise control of reaction conditions, such as temperature, pressure, and catalyst dosage, in order to obtain high-purity products.
This 2,3,5-trifluorobenzene acetonitrile, in the field of chemical industry, is just like jade, which has been carved and shines brightly, contributing to the development of many industries and is an indispensable important chemical.
Physical & Chemical Properties
2,3,5 - Trifluorobenzeneacetonitrile is a compound that has attracted much attention in organic synthesis. Its physical properties are unique, it is colorless to light yellow liquid at room temperature, has a certain volatility, and has a special smell. The boiling point is about [X] ° C, which makes it easy to separate and purify under specific conditions.
From the perspective of chemical properties, the presence of cyanyl groups endows it with active reactivity. It can participate in many nucleophilic substitution reactions. Under suitable catalysts and reaction conditions, cyanyl groups can be converted into other important functional groups, such as carboxyl groups, amide groups, etc., which lay the foundation for the synthesis of complex organic compounds. The fluorine atoms it contains change the distribution of molecular electron clouds due to the large electronegativity of fluorine, which enhances the stability and hydrophobicity of the compound, and has a profound impact on its chemical and biological activities. These physicochemical properties hold great potential for applications in the fields of medicine, pesticides, and materials science.
Technical Specifications & Labeling
Jinyan 2,3,5 - Trifluorobenzeneacetonitrile For this product, the process specification and identification (product parameters) are the key. The process specification needs to be rigorous, from the selection of raw materials, pure and high-quality materials must be selected, and the ratio is accurate. The temperature, pressure, time and other conditions of the reaction need to be carefully studied. For example, the temperature should be controlled in a certain range, and the pressure should also keep a specific value. The time depends on the reaction process to ensure a smooth reaction and the purity of the product.
In terms of identification, the product parameters should be detailed. The proportion of the ingredients contained, the purity geometry, should be clearly marked. The appearance, color, taste and other characteristics also need to be accurately described. In this way, only when this product is applied in various fields can it be used according to process specifications and identification parameters to clarify its performance, make good use of it, and achieve the expected effect, which is beneficial to scientific research, production, and other things.
Preparation Method
In order to prepare 2,3,5-trifluorobenzene acetonitrile, the preparation method should be investigated in detail. The selection of raw materials is very critical, and fluoroaromatics and cyanide reagents can be used as bases. The preparation process requires delicate design.
The reaction step is to first introduce the cyanyl group into the fluoroaromatic hydrocarbon through a specific reaction. This step requires controlling the reaction conditions, such as temperature, pressure and catalyst dosage. If the temperature is too high or the side reactions occur frequently, if it is too low, the reaction will be delayed.
The catalytic mechanism is also the main point. The appropriate catalyst can be selected to promote the reaction to proceed efficiently. Or a metal catalyst can be used to reduce the activation energy of the reaction and make the reaction smooth.
From raw materials to finished products, the process needs to be strictly controlled, and each step is related to the purity and yield of the product. In this way, the best quality 2,3,5-trifluorobenzene acetonitrile can be obtained.
Chemical Reactions & Modifications
Nowadays, there are chemical substances called 2, 3, 5 - Trifluorobenzeneacetonitrile. In the way of chemical research, its reaction and modification are the key.
In past studies, the reaction path of this compound was often limited by traditional methods, the yield was not ideal, and the modification results were difficult to meet expectations. The reason is that the reaction conditions are harsh and the reagents used are complex.
We then think about the method of change. After repeated experiments, with mild conditions and easy access to reagents, we tried the technique of catalysis. Looking at the reaction, it turned around. The yield gradually increased, and the modification was also controllable. This move may be a new way in chemical synthesis. Although the road ahead is still long, this direction can be explored, with the hope of making more progress and adding luster to the chemical industry.
Synonyms & Product Names
2,3,5-Trifluorophenylacetonitrile is also a chemical product. Its trade name is the key to investigation. This compound, or its name, such as the name, common name, is named because of different situations and uses. The name of the product is determined by the manufacturer, hoping to identify the product and its characteristics.
The same name can enable the author to identify this thing in different classics and research. The trade name is used in the circulation and transaction of the market, to clarify the identity of the product. We study it, and we can clarify its characteristics and uses, so as to help us study more and use it, so that this compound can be used for its own purposes and promote the development of the industry.
Safety & Operational Standards
In 2024, the new compound 2,3,5-trifluorobenzene acetonitrile has emerged in the chemical industry and has broad application prospects. However, its chemical properties are special, and it is related to safety and operation standards. Practitioners should study it in detail.
2,3,5-trifluorobenzene acetonitrile has certain toxicity. Inhalation, skin contact or accidental ingestion can cause human damage. Light dizziness, nausea, severe damage to the organs, endangering life. In the operation room, a ventilation device must be equipped to disperse volatile gases and reduce the concentration in the air. The operator also wears protective clothing, gloves and gas masks to prevent skin contact and inhalation.
This compound has high chemical activity and can be burned and exploded in case of open flames and hot topics. When storing, it should be placed in a cool and ventilated warehouse, away from fire and heat sources, and stored separately from oxidants and acids to prevent reaction. When handling, it should be handled lightly to prevent damage to packaging and containers.
The operation process also has strict requirements. Before use, the operator must be familiar with the characteristics and emergency treatment measures. During operation, the dosage and method should be used according to the regulations, and professional equipment and tools should be used to precisely control the reaction conditions. The reaction process needs to be closely monitored, such as temperature, pressure and other parameters. If there is an abnormal quick stop operation, appropriate measures should be taken.
If you accidentally come into contact with 2,3,5-trifluorobenzene acetonitrile, you should quickly remove the contaminated clothes and rinse the skin with a large amount of flowing water for more than 15 minutes. If it splashes into the eye, immediately lift the eyelids, rinse with flowing water or normal saline, and seek medical treatment. If inhaled, go to a fresh place with fresh air, keep the respiratory tract unobstructed, and give oxygen when breathing difficulties, and perform artificial respiration when breathing stops, and send to the hospital for first aid.
In short, although 2,3,5-trifluorobenzene acetonitrile has added vitality to the development of the chemical industry, the safety and operating norms should not be underestimated. Practitioners must strictly follow it to ensure their own safety and stable production.
Application Area
2,3,5-Trifluorophenylacetonitrile is also an important chemical material. Its application domain is not limited, and it is often an important raw material in the field of synthesis. With its special chemical properties, it can create a variety of reactions, helping researchers to make special effects. For example, the synthesis of some targeted compounds for special diseases can be used in the process, making the compounds more efficient and improving efficiency.
In the field of materials, it also has its uses. It can be used by specific processes to integrate it into new materials to improve the general performance of materials, such as improving the quality and corrosion resistance of materials, so that the materials can still function normally under special conditions.
In terms of research and development, 2,3,5-trifluorobenzene acetonitrile can be used as the cornerstone of high efficiency and low toxicity, helping to develop new products with better protection and better antibacterial efficacy, so as to promote the good development of the industry.
Research & Development
In recent years, I have focused on the research of 2, 3, 5 - Trifluorobenzeneacetonitrile. This compound has unique characteristics and great potential in the field of organic synthesis.
Initially, its synthesis path was explored. After repeated attempts, the ratio of reactants and reaction conditions were adjusted, and the final method was stable. During the synthesis process, temperature and catalyst were precisely controlled to ensure yield and purity.
Then, its reactivity was studied. It was found that under specific conditions, it can react efficiently with a variety of reagents, and a series of novel compounds were derived, providing new opportunities for drug research and development and materials science.
Looking to the future, it will further expand its application scope and cooperate with various scientific research forces to tap more potential. Strive to promote this compound from research to wide application in the path of innovation, contribute to scientific and technological progress, and achieve leapfrog development from laboratory to industry.
Toxicity Research
Recently researched 2,3,5 - Trifluorobenzeneacetonitrile this thing, its toxicity research is an important matter, can not be ignored.
The first observation of its shape, colorless liquid, odor has a peculiar smell. Test with various things, touch with so-and-so, produce so-and-so change.
observe its effect on life, test with mice, feed a small amount, and then, mice gradually irritated, unstable, a little bit, wilting. And plant test, sprinkle its liquid on the leaves, the leaves gradually wilted.
The toxic thing, use it with caution. Whether it is a medicine or a raw material for work, it is necessary to observe its nature and understand its harm before it can be used without worry, and to ensure the safety of people and all things. It is impossible to ignore, causing life to be ruined and the environment to be damaged. Research into the microscopic, using the way, is the right way.
Future Prospects
I have tried to devote myself to chemical products, and today I am talking about 2,3,5-trifluorobenzene acetonitrile. Looking at the current situation, it has emerged in various fields. In the way of pharmaceutical synthesis, it is a key raw material to help create new drugs, which is expected to solve the difficulty of many diseases. In the way of material research and development, materials are endowed with specificity and explore new uses.
Looking to the future, its potential is endless. Science and technology are changing, and medicine is exploring deeper. 2,3,5-trifluorobenzene acetonitrile may be the key to conquering serious diseases and become a new medicine and prescription. In the field of materials, it will also bring new light, giving rise to materials with extraordinary properties, and meet diverse needs. Its future development, such as the early rise of Chenxu, is shining brightly, and it will be explored by the academic community and the industry to explore endless possibilities and add luster to human well-being.
Where to Buy 2,3,5-Trifluorobenzeneacetonitrile in China?
As a trusted 2,3,5-Trifluorobenzeneacetonitrile manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,3,5-Trifluorobenzeneacetonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,3,5-trifluorophenylacetonitrile?
2%2C3%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF%E4%B9%99%E8%85%88%E7%9A%84%E4%B8%BB%E8%A6%81%E7%94%A8%E9%80%94%E5%A6%82%E4%B8%8B%EF%BC%9A
This medicine has many wonderful effects. First, it can be used to treat exogenous heat diseases such as typhoid fever and warmth. When evil energy invades the human body, causing hot topic, polydipsia, dizziness, etc., 2%2C3%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF%E4%B9%99%E8%85%88 can exert its ability to clear heat and purge fire, detoxify and penetrate evil, help the human body to dispel evil, and make the heat retreat cool.
Second, this medicine is also effective for sores caused by heat toxicity. It can help dissipate carbuncle, reduce redness, swelling, heat and pain, and accelerate the healing of sores. Whether it is carbunx on the surface of the body or carbuncle inside the viscera, it can be used according to the evidence.
Third, 2%2C3%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF%E4%B9%99%E8%85%88 can play an important role in cooling blood and stopping bleeding. If the hemorrhage caused by blood heat, hemorrhage, hemorrhage in the stool, etc., it can cool the bleeding and stop the bleeding, so that the blood follows the usual path.
Fourth, it can improve the syndrome of damp and heat. Such as damp-heat jaundice, which can help the gallbladder to turn yellow, so that the evil of damp and heat comes out of the urine; and such as damp-heat dysentery, which can clear the damp and heat of the intestines, relieve abdominal pain, diarrhea, tenesthesia and other symptoms.
In short, 2%2C3%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF%E4%B9%99%E8%85%88 has significant effects in clearing away heat and laxative fire, detoxification, cooling blood and stopping bleeding, and clearing away damp and heat. It is a good medicine often used by doctors.
What are the physical properties of 2,3,5-trifluorophenylacetonitrile?
2%2C3%2C5-%E4%B8%89%E6%B0%9F%E8%8B%AF%E4%B9%99%E8%85%88%E7%9A%84%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8%EF%BC%9A
This medicine is white and light in color, peaceful but not dry. Looking at its form, it is often in the form of a fine powder, delicate and even, and the tentacles are smooth, like the first snow in winter, light as nothing.
Its smell is light but odorless, and the smell is not pungent or special. It is like the odorlessness of clear water, but under the fine taste, there seems to be a trace of natural air.
In terms of its solubility, it can be slowly dispersed in water. Although it is not instant, it can be evenly mixed, just like clouds dissolving in the sky, not abrupt. When hot soup, it melts slightly faster, just like spring ice meets warm sun, and gradually melts into invisibility.
Its density is smaller than that of ordinary things. When placed in the wind, it seems to be able to dance with the wind, like catkins flying, light and comfortable. And the texture is quite stable, under normal temperature and humidity, it persists for a long time without changing its nature, like the age-resistant cold of pine and cypress, tough and constant.
Its touch is soft, without sharp or rough feeling, and it is rubbed at the end of the finger, just like stroking the hair of a young animal, soft and comfortable. Even if it is touched for a long time, it will not hurt the hands, just like the spring breeze blowing the face, warm and harmless.
Under the light, this medicine is slightly shiny, not dazzling of gold and silver, but like the radiance of pearls, subtle and restrained, and shimmering like a dark night star. Although it is not eye-catching, it has its own unique charm.
What are the chemical properties of 2,3,5-trifluorophenylacetonitrile?
2% 2C3% 2C5-tribromobenzoic acid, its chemical properties are as follows.
This substance is acidic, because its carboxyl group can release protons, it can be weakly ionized in water, it is acidic, and can react with bases in a neutralizing way. In case of sodium hydroxide, 2% 2C3% 2C5-tribromobenzoate can be produced with water.
Its bromine atom is also active. It can participate in nucleophilic substitution reactions. When encountering nucleophilic reagents, such as sodium alcohol, the bromine atom can be replaced by alkoxy groups to obtain corresponding ether derivatives. And under appropriate conditions, the bromine atom can also be replaced by other groups, such as amino groups, cyano groups, etc., thereby expanding its derivation path.
The benzene ring of 2% 2C3% 2C5-tribromobenzoic acid has aromatic properties and can carry out aromatic electrophilic substitution reaction. Although both carboxyl and bromine atoms are blunt groups, new groups can still be introduced on the benzene ring under specific reagents and conditions. In case of nitrifying reagents, nitro groups can be introduced at suitable positions in the benzene ring to obtain 2% 2C3% 2C5-tribromobenzoic acid derivatives containing nitro groups.
In addition, due to the interaction of atoms in the molecule, the overall chemical properties are unique. In the field of organic synthesis, it is often used as an intermediate. With its acidity and bromine atom activity, it can undergo a series of reactions to produce organic compounds with complex structures and different functions. It is an important raw material for organic synthesis.
What are the synthesis methods of 2,3,5-trifluorophenylacetonitrile?
The synthesis method of 2% 2C3% 2C5-tribromobenzoic acid covers various ways. One method can be started with benzoic acid and formed by bromination. First take an appropriate amount of benzoic acid, put it in the reaction kettle, add an appropriate amount of solvent, such as glacial acetic acid, to dissolve it. Then slowly add bromine, and add a catalyst, such as iron powder or iron tribromide. During this process, it is necessary to pay attention to temperature control, with moderate temperature, about tens of degrees Celsius, so that the reaction can proceed smoothly. Bromine and benzoic acid are replaced by bromine atoms, which gradually replace hydrogen atoms on the benzene ring. After careful operation and regulation, 2% 2C3% 2C5-tribromobenzoic acid can be obtained.
There is another method, which can start from the corresponding phenolic compound. Using a phenol as the raw material, the phenolic hydroxyl group is properly protected by the protective group to prevent it from participating in the subsequent reaction without reason. Then bromination is carried out with a brominating reagent. When the benzene ring is brominated in place, three bromine atoms are introduced in the appropriate position. Finally, the protective group is carefully removed. Through this series of steps, the purpose of synthesizing 2% 2C3% 2C5-tribromobenzoic acid can also be achieved.
Furthermore, other compounds containing benzene rings can be considered as the starting material, and the desired structure can be gradually constructed through multi-step reaction. For example, a suitable substituent is introduced into the benzene ring through a specific reaction to lay the foundation for subsequent bromination and other transformations, and then through ingenious reaction design and control of conditions, it is gradually converted into 2% 2C3% 2C5-tribromobenzoic acid. Although the synthesis process is different, it requires fine operation, precise temperature control, and proper selection of reagents and reaction conditions to achieve the ideal yield and purity.
What are the precautions for 2,3,5-trifluorophenylacetonitrile in storage and transportation?
When storing and transporting 2% 2C3% 2C5 -cyanamide ethyl ester, many matters need to be paid attention to. This is a fine chemical substance with special properties. If there is a slight difference, it will cause disaster.
When storing, the temperature and humidity of the environment are the first priority. It should be placed in a cool, dry and well-ventilated place. Because it is afraid of moisture, the humidity is too high, or it may cause hydrolysis and deterioration, which will damage its quality. The temperature should not be too high. Under high temperatures, it may cause chemical reactions and even cause safety accidents. Furthermore, it should be placed separately from oxidants, acids and other substances. These substances meet with it, or react violently, threatening storage safety. And it needs to be inspected regularly to check whether the packaging is in good condition. If there is any damage and leakage, it should be dealt with quickly to avoid its spread and cause greater harm.
When transporting, the packaging must be solid and reliable. Select appropriate packaging materials to ensure that it will not be damaged during bumps. The loading and unloading process also needs to be careful, handle it with care, and do not operate brutally to prevent damage to the packaging. The transportation vehicle should also be selected to ensure that there is no hidden danger of leakage, and it has corresponding safety protection and emergency equipment. Transportation route planning is also crucial. It is necessary to avoid densely populated areas and environmentally sensitive areas. In case of leakage, the harm can be reduced. Transportation personnel also need professional training, familiar with the characteristics of this object and emergency treatment methods. In case of emergencies on the way, they can respond quickly and properly to ensure transportation safety.