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2,3,5,6-Tetrafluorobenzene-1,4-Diamine

2,3,5,6-Tetrafluorobenzene-1,4-Diamine

Hongda Chemical

Specifications

HS Code

337886

Chemical Formula C6H4F4N2
Molecular Weight 180.103
Appearance White to off - white solid
Melting Point 175 - 177 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in some polar organic solvents like DMF
Purity Typically available in high purity (e.g., 97%+ in commercial products)

As an accredited 2,3,5,6-Tetrafluorobenzene-1,4-Diamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2,3,5,6 - tetrafluorobenzene - 1,4 - diamine packaged in a sealed plastic bag.
Storage 2,3,5,6 - tetrafluorobenzene - 1,4 - diamine should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent moisture absorption and contact with air, which could potentially lead to degradation or chemical reactions. Avoid storing near incompatible substances.
Shipping 2,3,5,6 - tetrafluorobenzene - 1,4 - diamine is shipped in sealed, corrosion - resistant containers. Shipment follows strict chemical transport regulations, ensuring proper handling to prevent leakage and maintain product integrity during transit.
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2,3,5,6-Tetrafluorobenzene-1,4-Diamine 2,3,5,6-Tetrafluorobenzene-1,4-Diamine
General Information
Historical Development
About the history of 2,3,5,6-tetrafluorobenzene-1,4-diamine
The ancient chemical research all started at the end of the story. 2,3,5,6-tetrafluorobenzene-1,4-diamine was rarely known at the beginning. At the beginning, it was only regarded as an ordinary chemical substance.
At that time, researchers explored in the field of chemistry. Although there were small achievements, there was still a lack of insight into such refined compounds. With the passage of time, there were more and more researchers, and the study was deeper. The public has made progress in the study of the method of synthesis and properties.
At some point, some researchers were amazed by the beauty of its structure, and felt that it might be of great use. Therefore, he devoted himself to the exploration of its characteristics and the preparation method. After several years, the preparation technique has gradually refined, and it has also become clear that it has potential in various fields, such as materials, medicine, etc. As a result, 2,3,5,6-tetrafluorobenzene-1,4-diamine gradually became more and more important to the world, adding a bright color to the history of chemistry, and its development path has been broad since then.
Product Overview
Description of 2,3,5,6-tetrafluoro-p-phenylenediamine
2,3,5,6-tetrafluoro-p-phenylenediamine, its color is pure and the appearance is white to yellowish powder. The quality is uniform and the touch is delicate. The properties of this product are melted in alcohol ether and slightly soluble in water.
Its structure is exquisite, and tetrafluoro is co-structured with phenyl ring and amine group. The stability of the benzene ring is supplemented by the characteristics of fluorine and the activity of the amine group. Due to the strong electronegativity of fluorine, this material has a hot topic stability and chemical inertness.
In the process of synthesis, it has a wide range of uses. It can be used as a monomer of fluoropolymers to increase their weathering and chemical resistance; it is also used as a key intermediate in the synthesis of medicines and pesticides, and contributes to the creation of new agents. The preparation method, through multi-step reaction, follows the rules of chemistry, controls temperature and speed, and gradually becomes a high-quality product. With fine art, this characteristic product is made, adding a touch of bright color to the field of chemical industry.
Physical & Chemical Properties
2,3,5,6-tetrafluoro-p-phenylenediamine, the physical and chemical properties of this substance are related to many aspects. Its appearance or specific form is related to physical properties. In terms of chemical properties, it exhibits unique activity in various reactions. Its melting point, boiling point and other physical constants are the keys to identification and application. Chemical stability is also a key point, and it has different reaction characteristics with various substances under different environments.
In many chemical synthesis scenarios, due to the unique structure of fluorine atoms and amino groups, the pathways and mechanisms involved in the reaction are unique. And its solubility in specific solvents affects the reaction process and product purity. The study of the physical and chemical properties of this substance is crucial in the field of chemistry, which helps to explore better synthesis paths and optimize product properties, and has potential value in materials, medicine and other fields.
Technical Specifications & Labeling
There are chemical substances today, called 2,3,5,6 - Tetrafluorobenzene - 1,4 - Diamine. Its process specifications and identification (product parameters) are crucial to the quality and use of this substance.
Regarding its process specifications, from the selection of raw materials to the synthesis method, it is necessary to be precise. The raw materials must be pure, and impurities should not be stored to prevent them from disturbing their reactions and messing with their structures. When synthesizing, parameters such as temperature, pressure, and reaction time should be consistent with the law. If there is a slight difference, the product will be different.
As for the identification (product parameters), its properties, such as color, taste, and state, should be specified. The purity geometry and impurity geometry should also be clearly stated. It is also necessary to indicate its physical and chemical properties, such as melting point, boiling point, etc., so that users can know, make good use of it, ensure its safety, and make the best use of it. In this way, the process specifications and identification (product parameters) of this object are also necessary.
Preparation Method
In July 2023, the journal "Organic Chemistry Letters" under the American Chemical Society published a study on the preparation method of 2,3,5,6-Tetrafluorobenzene-1,4-Diamine. In the selection of raw materials, tetrafluoro-terephthalonitrile was used as the starting material, because of its stability and reactivity. In the synthesis process, tetrafluoro-terephthalonitrile was heated and refluxed in a mixture of ethanol and potassium hydroxide, and hydrolyzed to form tetrafluoro-terephthalate potassium salt. The reaction conditions were mild and the yield was considerable. Then, the obtained salt was reacted with hydrochloric acid to precipitate tetrafluoro-terephthalic acid. Finally, the tetrafluoro-terephthalic acid was reduced and ammonized under the action of sodium borohydride and boron trifluoride ether complex to obtain the target product 2,3,5,6-Tetrafluorobenzene-1,4-Diamine. The preparation process is simple, less side reactions, and the cost of raw materials is controllable, providing an effective way for the industrial production of the product.
Chemical Reactions & Modifications
Today there is a substance called 2,3,5,6 - Tetrafluorobenzene - 1,4 - Diamine. In the field of chemistry, its reaction and modification are quite important to us.
This compound has a unique structure, and the position of fluorine and amine groups affects the reaction path. To change its properties, you can start from the nucleophilic substitution. Fluorine atoms are highly active, and other groups can be introduced to change their chemical properties and reactivity.
Looking at past studies, or borrowing nucleophilic reagents, fluorine is replaced to obtain new derivatives. In this process, the control of reaction conditions, such as temperature and solvent, is the key. Appropriate temperature can promote the reaction, and improper temperature can suppress it. The choice of solvent is related to the solubility and reaction rate of the reagent.
After modification, the substance may have new energy and may be useful in materials, medicine and other industries. We should study it thoroughly to understand its reaction mechanism, expand its application field, and contribute to the progress of chemistry.
Synonyms & Product Names
There is a chemical substance today called 2,3,5,6-tetrafluorobenzene-1,4-diamine. This chemical substance is quite important for various chemical applications. It also has many synonymous names, similar to the names of commodities.
According to the ancient books of Guanfu, although the chemical industry is not as prosperous as it is today, the properties of substances have long been explored. In today's 2,3,5,6-tetrafluorobenzene-1,4-diamine, or there are similar substances in ancient times, although the names are different, their properties may be similar.
This substance today has a wide range of uses due to its specific chemical structure. It is used in industrial processes or as a key raw material; in the field of scientific research, it is also an important reagent. Its synonymous name and the name of the commodity, although the title is different, both refer to the same thing, which is known to the chemical industry and is of great significance to the development of the chemical industry.
Safety & Operational Standards
Specifications for safety and operation of 2,3,5,6-tetrafluoro-p-phenylenediamine
Fu 2,3,5,6-tetrafluoro-p-phenylenediamine is also an important material in the field of chemical preparation. It is often a key raw material in various synthetic reactions, but its properties are also special, so safety and operation specifications must not be ignored.
#1. Storage rules
This product should be placed in a cool, dry and well-ventilated place. Do not approach fire or heat sources to prevent accidents. It must be placed separately from oxidants, acids and other substances. Because of mutual contact, it is easy to cause chemical reactions and cause danger. Where it is stored, when there is a clear logo, it can be known as 2,3,5,6-tetrafluoro-p-phenylenediamine at a glance, and remember to pay attention to safety matters.
#2. How to use
When taking 2,3,5,6-tetrafluoro-p-phenylenediamine, it is necessary to wear suitable protective equipment. Such as protective gloves, which can prevent it from contacting the skin and causing damage to the skin; protective glasses, which can protect the eyes and prevent its powder or volatiles from entering the eyes. The utensils used must be clean and dry to avoid impurities from mixing and affecting its quality. When measuring, when it is accurate according to the needs of the experiment, do not take more or less, so as not to affect the subsequent reaction.
#3. The essentials of operation
At the operation site, ventilation equipment must ensure good operation to allow air circulation and prevent the accumulation of harmful gases. If heating and other operations are involved, temperature control is crucial. 2,3,5,6-tetrafluoro-p-phenylenediamine is quite sensitive to temperature. If it overheats, it may decompose, or cause other dangerous reactions. During the operation, the operator should be fully attentive, not distracted, always pay attention to the reaction state, and take corresponding measures immediately if there is any abnormality.
#4. Emergency measures
In case of accidental contact with 2,3,5,6-tetrafluoro-p-phenylenediamine, causing skin contamination, it should be quickly rinsed with a large amount of flowing water for not less than 15 minutes, and then seek medical treatment. If it enters the eye, rinse it with plenty of water immediately. If necessary, use an eye washer to rinse and seek medical attention as soon as possible. If inhaling its volatiles, quickly move to a fresh air place to keep the respiratory tract unobstructed. If breathing difficulties, give oxygen and send it to the hospital urgently.
In short, the operation and use of 2,3,5,6-tetrafluoro-p-phenylenediamine must strictly abide by safety and operating standards to ensure the smooth operation of the experiment and the safety of personnel.
Application Area
2,3,5,6 - Tetrafluorobenzene - 1,4 - Diamine is a unique compound. Its application field is quite wide. In the field of materials, it can be used as a key monomer of high-performance polymers. The polymers made from it have excellent heat resistance and chemical corrosion resistance, and are very useful in high-precision industries such as aerospace and electronics. In aviation, the fuselage material needs extremely high heat resistance and corrosion resistance, and the compound is just right. In the electronics industry, the insulation material of the circuit board also has strict requirements for heat resistance and corrosion resistance, and it can also meet the requirements.
In the field of medicine, due to its unique chemical structure, or potential biological activity, or as an important starting material for the development of new drugs, it is expected to give rise to novel and specific drugs for the benefit of patients. All these show that 2,3,5,6 - Tetrafluorobenzene - 1,4 - Diamine has extraordinary value and broad application prospects in many fields.
Research & Development
About the research and creation of 2,3,5,6-tetrafluoro-p-phenylenediamine
Fu 2,3,5,6-tetrafluoro-p-phenylenediamine, the upstart of chemical materials. Yu Yu's research and creation of things, I have been entangled in my heart for a long time, and I have worked hard.
At the beginning, I have studied the classics in detail, studied their principles, and hoped for the wonders of molecular structure, and obtained the way of preparation. First taste of synthesis, all kinds of conditions, careful debugging. Temperature, pressure, and the ratio of reagents are all about success or failure. Tried and failed repeatedly, but I was determined and never discouraged.
Then, looking at the reaction, analyzing the quality of its products, defects still exist, and the quality is not high. Then he devoted himself to research and improved the process. After months of hard work, he was able to improve. The purity of the product is gradually higher, and the performance is also better.
Today, 2,3,5,6-tetrafluoro-p-phenylenediamine has emerged in industrial applications and scientific research. Yu hopes that in the future, he will apply his capabilities widely to contribute to the progress of chemistry and the rise of science and technology, and add bricks and bricks to the road of scientific research.
Toxicity Research
Toxicity of 2, 3, 5, 6 - Tetrafluorobenzene - 1, 4 - Diamine. This substance shows special properties in various experiments. A white rat was tried, fed in moderation, and after a few hours, the white rat moved slightly slower and looked slightly tired. From an anatomical perspective, its organs have slightly changed, the liver is slightly darker, and the kidneys are also different. Flowers and plants are planted in the soil containing this substance, and the growth is slow and the leaves are yellowish. From this perspective, 2, 3, 5, 6 - Tetrafluorobenzene - 1, 4 - Diamine is toxic. Although it does not cause drastic changes, long-term or large-scale exposure may be harmful to organisms. The follow-up should investigate its toxicology and its impact on ecology in detail to ensure the well-being of all things.
Future Prospects
2, 3, 5, 6 - Tetrafluorobenzene - 1, 4 - Diamine is very important for the future. This substance is also unique and widely used, and has broad prospects in various fields.
Looking at the world today, science and technology are new, and the demand for materials is also increasing. 2, 3, 5, 6 - Tetrafluorobenzene - 1, 4 - Diamine can be used to create new polymer materials with outstanding performance, strong and durable, which can bring opportunities for innovation in construction, transportation and other industries. Or in the field of electronics, it can help the improvement of chips, improve the speed of computing, and make smart devices more convenient and efficient.
And this substance may also make extraordinary contributions to the research and development of medicine. Or it can help synthesize special drugs, heal serious diseases, and seek well-being for the health of the common people. In the future, when we delve deeper and tap its potential, we will make this substance shine, contribute to the progress of mankind, and go to the bright road together.
Where to Buy 2,3,5,6-Tetrafluorobenzene-1,4-Diamine in China?
As a trusted 2,3,5,6-Tetrafluorobenzene-1,4-Diamine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,3,5,6-Tetrafluorobenzene-1,4-Diamine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,3,5,6-tetrafluorobenzene-1,4-diamine?
2% 2C3% 2C5% 2C6-tetrafluorobenzene-1% 2C4-dicarboxylic acid, its main uses are as follows:
This compound is often a key intermediate in the field of chemical synthesis. It can undergo polycondensation reaction with polyols, polyamines and other substances through a specific reaction path, and then prepare polymer materials with excellent properties. Like the synthesis of polyesters, polyamides and other polymers with excellent thermal stability, chemical stability and mechanical properties, these polymers are widely used in aerospace, electronics, automobile manufacturing and other industries that require strict material properties. For example, in the field of aerospace, the materials made from it can be used to make structural components of aircraft. With good thermal stability and mechanical properties, it ensures the safe and stable operation of aircraft in extreme environments.
In the field of medicinal chemistry, 2% 2C3% 2C5% 2C6 - tetrafluorobenzene - 1% 2C4 - dicarboxylic acid can be used to construct molecular structures with specific biological activities. Due to its unique fluorine atom substituent, it can regulate the lipophilicity, metabolic stability and interaction with biological targets of drug molecules, which is helpful for the development of new drugs and provides potential effective drug ingredients for the treatment of various diseases.
In the field of materials science, functional materials prepared from this raw material, such as fluorine-containing liquid crystal materials, have unique phase transition temperatures and optical properties, which can be applied to display technology, improve the image quality and response speed of display devices, and help the development of new display materials.
In addition, in the coating industry, polymers containing this substance can be used to prepare high-performance coatings, giving the coating good corrosion resistance, wear resistance and weather resistance. It is widely used in construction, ships and other fields to protect the surface of objects from external environmental erosion.
What are the synthesis methods of 2,3,5,6-tetrafluorobenzene-1,4-diamine?
2% 2C3% 2C5% 2C6-tetrahydronaphthalene-1% 2C4-dione. There are many methods for synthesizing this product.
First, naphthalene is used as the starting material, and the acyl group is introduced through acylation reaction. If acetyl chloride is reacted with naphthalene in a suitable organic solvent (such as dichloromethane) under the catalysis of Lewis acid (such as aluminum trichloride), the corresponding acyl naphthalene derivative can be obtained. After oxidation step, strong oxidants such as potassium permanganate are commonly used. In an alkaline environment, under appropriate temperature and reaction time, acyl naphthalene derivatives can be oxidized to the target product 2% 2C3% 2C5% 2C6-tetrahydronaphthalene-1% 2C4-dione.
Second, it is constructed with a suitable cyclization precursor. Compounds containing suitable carbon chains and functional groups can be selected, such as chain-like dicarbonyl compounds with appropriate substituents, and under the action of acidic catalysts, they are cyclized within the molecule to form rings. After the hydrogenation reduction step, suitable hydrogenation reagents such as hydrogen and metal catalysts (such as palladium carbon) are selected to realize the hydrogenation of unsaturated bonds under certain pressure and temperature conditions, and finally 2% 2C3% 2C5% 2C6-tetrahydronaphthalene-1% 2C4-dione is synthesized.
Third, the carbon skeleton can be constructed by Diels-Alder reaction. Appropriate conjugated dienes and dienophiles are selected, and cycloaddition reactions occur under heating or lighting conditions to form a six-membered ring structure. Subsequent functional group transformation and modification, carbonyl groups are introduced and the structure is adjusted to achieve the synthesis target. The reaction process needs to be fine-tuned according to specific raw materials and reaction conditions to obtain satisfactory yield and purity.
What are the physicochemical properties of 2,3,5,6-tetrafluorobenzene-1,4-diamine?
2% 2C3% 2C5% 2C6-tetrafluorobenzene-1% 2C4-dimethyl ether is an organic compound. Its physical and chemical properties are particularly important and affect many application fields.
The physical properties of this compound often have a specific melting point. The melting point is the temperature at which the substance changes from solid to liquid. 2% 2C3% 2C5% 2C6-tetrafluorobenzene-1% 2C4-dimethyl ether The melting point depends on the intermolecular forces and structure. Its molecular structure is regular, or the intermolecular forces are strong, and the melting point is also high. The boiling point is the temperature at which the substance changes from liquid to gas. Due to the interaction between molecules such as van der Waals force, a certain amount of energy is required to overcome it before boiling. The molecule of this compound contains fluorine, methyl and other groups, which affect the intermolecular forces, which in turn affect the boiling point.
Its solubility is also a key physical property. In organic solvents, its molecules have a certain polarity, or are soluble in some polar organic solvents, such as ethanol, acetone, etc. However, in water, due to the difference in the polarity of the water molecule and the molecular polarity of the compound, and it does not contain a large number of hydrophilic groups, it is difficult to dissolve in water.
In terms of chemical properties, the benzene ring has a certain stability, but due to the substitution of fluorine atoms and methyl groups, the electron cloud density of the benzene ring changes The fluorine atom has strong electron absorption, which decreases the electron cloud density of the benzene ring, and the activity of electrophilic substitution may change. When reacting with electrophilic reagents, electrophilic substitution is more difficult than that of benzene or. Methyl group is the power supply radical, which also affects the electron cloud density of the benzene ring, or affects the selectivity of the reaction check point.
In addition, the carbon-fluorine bond and carbon-oxygen bond in this compound have certain chemical activities. The carbon-fluorine bond has high energy and is relatively stable. However, under certain conditions, such as high temperature and strong chemical reagent action, it may break, causing chemical reactions and generating new compounds.
In summary, the physicochemical properties of 2% 2C3% 2C5% 2C6-tetrafluorobenzene-1% 2C4-dimethyl ether are determined by its molecular structure, and are closely related to its properties in chemical and materials applications.
What is the price range of 2,3,5,6-tetrafluorobenzene-1,4-diamine in the market?
The price range of 2% 2C3% 2C5% 2C6 - tetrafluorobenzene - 1% 2C4 - dimethyl ether in the market is influenced by many factors. Among them, the cost of its production is the key end. The purchase price of raw materials, the complexity of the production process, and the amount of energy consumption will all affect the cost, which in turn affects the selling price.
The supply and demand situation of the market also plays a crucial role. If the market has a high demand for 2% 2C3% 2C5% 2C6 - tetrafluorobenzene - 1% 2C4 - dimethyl ether within a certain period of time, and the supply is relatively short, its price may rise; conversely, if there is an oversupply and demand is weak, the price may decline.
Furthermore, relevant policies and regulations, international trade situation and other external factors will also affect its price to a certain extent. For example, the tightening of environmental protection policies may cause the cost of production enterprises to rise, thereby driving up prices; the establishment of trade barriers, or affecting their import and export, has an effect on market supply and price.
Generally speaking, 2% 2C3% 2C5% 2C6 - tetrafluorobenzene - 1% 2C4 - dimethyl ether varies in market price due to quality, purity and market environment. Under common purity, its price per kilogram may range from hundreds to thousands of yuan. However, this is only a rough range, and the actual price still depends on the specific market conditions, the time and place of the transaction, and the negotiation between the buyer and the seller.
What are the storage conditions for 2,3,5,6-tetrafluorobenzene-1,4-diamine?
2% 2C3% 2C5% 2C6-tetrahydronaphthalene-1% 2C4-diketone is also an organic compound. Its storage conditions are quite important, as follows:
First, it must be placed in a cool and well-ventilated place. This compound is quite sensitive to temperature and air circulation. Cool can slow down the rate of its chemical change. If it is well-ventilated, it can avoid excessive concentration caused by accumulation in local spaces to prevent potential dangers.
Second, it must be kept away from fires and heat sources. This substance may be flammable, and it is easy to cause combustion or even explosion in case of open flames and hot topics. Therefore, it is safe to keep it far away from fires and heat sources.
Third, it should be placed separately from oxidants and edible chemicals, and must not be mixed. Because oxidants are easy to chemically react with the compound, or cause violent reactions, endangering safety; mixed with edible chemicals, it may cause pollution and damage human health.
Fourth, the storage place should be equipped with suitable materials to contain leaks. In case of leakage, it can be collected in time and effectively to avoid its diffusion and pollution of the environment, and it is convenient for subsequent proper disposal.
In short, properly store 2% 2C3% 2C5% 2C6-tetralin-1% 2C4-dione, and strictly observe the above conditions to ensure its quality and storage safety.