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2,3,4-Trifluorobenzeneacetonitrile

2,3,4-Trifluorobenzeneacetonitrile

Hongda Chemical

Specifications

HS Code

942543

Chemical Formula C8H3F3N
Molar Mass 171.11 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 186 - 188 °C
Melting Point N/A
Density 1.287 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 72 °C
Refractive Index 1.446 (20 °C)

As an accredited 2,3,4-Trifluorobenzeneacetonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2,3,4 - trifluorobenzeneacetonitrile packaged in a sealed, chemical - resistant bottle.
Storage 2,3,4 - trifluorobenzeneacetonitrile should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container to prevent leakage and vapor release. It is best stored in a dedicated chemical storage cabinet, clearly labeled, following local safety regulations for handling and storing hazardous chemicals.
Shipping 2,3,4 - trifluorobenzeneacetonitrile is shipped in accordance with strict chemical transportation regulations. It is typically packed in sealed, corrosion - resistant containers to prevent leakage during transit, ensuring safety.
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2,3,4-Trifluorobenzeneacetonitrile 2,3,4-Trifluorobenzeneacetonitrile
General Information
Historical Development
Wenfu 2,3,4-trifluorobenzene acetonitrile has a reason for its prosperity. Looking at the past, the progress of chemistry is step by step. At the beginning, everyone was in the way of organic synthesis, and they worked tirelessly to find new products to meet all needs.
On the way to synthesis, Zhu Xian Da worked hard. There were wise people who first gained insight into the molecular structure, and introduced fluorine atoms on the side of phenylacetonitrile by means of fluoride substitution. At the beginning, it was difficult to try, and the yield was quite low, but everyone was not discouraged. After repeated experiments, adjusting conditions, and selecting reagents, they gradually got to the door.
At some point, the process was slightly fixed, and the yield gradually increased. 2,3,4-trifluorobenzene acetonitrile began to appear in laboratories. After being pondered by various craftsmen, the process was optimized, and mass production could be expected. Since then, this product has emerged in the fields of medicine, materials, etc., adding new power to various research and production. Its development process is one of the spots in chemical evolution, witnessing the spirit of our generation's endless exploration.
Product Overview
Today there is a product called 2,3,4-trifluorobenzene acetonitrile. It is a key raw material for organic synthesis and has a wide range of uses in medicine, pesticides and other fields. Looking at its properties, it is colorless to light yellow liquid at room temperature, has a special odor, and has a certain volatility.
The preparation of this substance is often obtained by multi-step chemical reaction with specific fluorobenzene derivatives and cyanide reagents. The reaction process requires precise control of temperature, pH and other conditions to ensure the purity and yield of the product.
Its chemical properties are active. Because it contains cyanide groups and fluorine atoms, it can participate in many reactions such as nucleophilic substitution and addition, thereby constructing complex organic molecular structures.
At the application level, when creating new drugs, it can significantly improve drug activity, stability and bioavailability; in the field of pesticides, it helps to develop high-efficiency, low-toxicity and environmentally friendly pesticides.
2,3,4-trifluorobenzene acetonitrile, with its unique chemical properties and wide range of uses, has a promising future in chemical research and development.
Physical & Chemical Properties
2,3,4-Trifluorophenylacetonitrile is also an organic compound. Its physical and chemical properties are particularly important and affect many applications. Looking at its physical properties, at room temperature, this substance is often colorless to pale yellow liquid, with a specific boiling point and melting point, and has a certain density. It is soluble in many organic solvents. As for its chemical properties, its cyanide group is active and can participate in many chemical reactions, such as nucleophilic addition. Because of its fluorine atom, the molecule has unique electronic effects and spatial effects, which affect its reactivity and selectivity. This compound has a wide range of uses in the field of organic synthesis. It can be used as a key intermediate to help prepare a variety of fluorine-containing compounds, contributing to the development of medicinal chemistry, materials science and many other disciplines.
Technical Specifications & Labeling
Today there are 2,3,4 - Trifluorobenzeneacetonitrile of this substance, which is very important in the field of chemical industry. Its process specifications and identification (product parameters) are the key to production and application.
Process specifications, from the selection of raw materials, need to be pure in texture, almost no impurities, in order to ensure a smooth reaction. The reaction conditions also need to be precisely controlled, the temperature should be stable in a certain range, and the fluctuation should not be millimeter; the pressure should also be constant, so that the reaction proceeds in sequence.
In terms of identification (product parameters), the purity should reach a very high standard, and the color should be clear and transparent without any variegation. Its physical properties, such as melting point and boiling point, should be in line with the established number, which is a sign of quality. In this way, we have high-quality 2, 3, 4 - Trifluorobenzeneacetonitrile products to meet the needs of all parties.
Preparation Method
The method of making 2,3,4-trifluorobenzene acetonitrile is related to the raw materials and production process, reaction steps, and catalytic mechanism. The raw materials need to be pure and compatible, such as trifluorobenzene and acetonitrile as the base, supplemented by a specific catalyst.
The first step of the reaction is to precisely prepare the proportion of raw materials and put them into a special reactor. The temperature is controlled in a suitable range, about one hundred and twenty degrees Celsius, and fine-tuned according to the reaction process. The catalyst plays a key role in promoting the efficient progress of the reaction. The catalytic mechanism is to reduce the activation energy of the reaction, greatly increase the activity of the molecule, and speed up the reaction rate.
The production process also needs to be carefully controlled, the material mixing needs to be uniform, and the reaction time is about three hours After the reaction is completed, the product with high purity of 2,3,4-trifluorobenzene acetonitrile is purified by distillation, extraction and other processes to meet the needs of industry and scientific research.
Chemical Reactions & Modifications
Taste the wonders of chemical industry, it is related to the change of all things. In today's discussion of 2,3,4-Trifluorobenzeneacetonitrile, its chemical reaction and modification are quite crucial.
To make this product, the methods of the past may not be good. Common reactions, harsh conditions, yield is not high. The reason is that the activity of the reactants varies, the reaction is blocked, and the side reactions are frequent, disturbing its purity.
However, today is different from the past. Scholars are working hard to improve the method. Or choose a new catalyst to increase the activity of the reactants and promote the smooth reaction, and the yield must also be improved. Or optimize the reaction environment, control the temperature and adjust the pressure accurately, so that the side reactions are sharply reduced and the purity of the product is greatly increased. Such a chemical change is like clearing the clouds to see the sun, making the preparation of this substance more refined and its application more extensive. It adds a touch of color to the chemical industry and paves the way for subsequent research and use.
Synonyms & Product Names
Today there is a thing called 2,3,4-trifluorobenzene acetonitrile. Its synonyms and synonyms are quite important. In my research on chemistry, I know that there are many of these things, and they are called differently due to different industry habits and uses.
I have heard that this thing also has another name. In the market or due to different processes and uses, I call it by another name. Although the names are different, it is actually the same thing. Like the ancient medicines, they are called one place and one place, but their properties are the same. This 2,3,4-trifluorobenzene acetonitrile, or in the process of synthesis, according to the reaction it participates in and the product it is made, gets another name; or in the application, according to what its effect is, it gets a new name.
When we study this thing, we should understand its various names, so as not to be confused. Just like walking in the wrong way, we need to know the names of various paths in order to travel freely, and the same is true in the study of chemistry. In this way, we can accurately grasp, and in the synthesis and application of all things, there will be no mistakes.
Safety & Operational Standards
Specifications for the safety and operation of 2,3,4-trifluorophenylacetonitrile
Fu 2,3,4-trifluorophenylacetonitrile is an important substance in chemical research. During the experimental operation, safety is the top priority, and many norms need to be followed.
Its properties are dangerous, and it can be harmful if it touches the skin, inhaled or taken by mistake. Therefore, when operating, protective equipment is indispensable. Wear protective gloves and goggles in front of appropriate protective clothing to prevent direct contact with the body.
Furthermore, the operating environment should be well ventilated. If the gas emitted by this substance accumulates in a confined space, it may cause danger. Ventilation equipment can effectively remove harmful gases and ensure the safety of the experimenter.
When taking 2,3,4-trifluorobenzene acetonitrile, the method must be precise and careful. According to the amount required for the experiment, measure it with suitable utensils. Do not dump it at will to prevent pollution and danger from spilling. After measuring, close the container in time to prevent its volatilization.
If 2,3,4-trifluorobenzene acetonitrile is accidentally spilled, do not panic. Cover it with an appropriate adsorption material immediately, collect and deal with it to prevent its spread. Those who deal with the spill also need to take good protection.
After the experiment is completed, the utensils used should be cleaned in time. The remaining 2,3,4-trifluorobenzene acetonitrile should not be disposed of at will, but should be disposed of uniformly according to regulations to protect the environment and the safety of others.
In general, in the research and operation of 2,3,4-trifluorobenzene acetonitrile, safety and standardization are the most important. Strict adherence to various guidelines can avoid danger, ensure the smooth progress of the experiment, and protect the health of personnel.
Application Area
2,3,4-Trifluorophenylacetonitrile is also a stunner in chemical engineering. Its application domain,. In the field of research and development, it can be the cornerstone of exquisite technology, helping to overcome all kinds of diseases. Because of its specialization, it can cleverly fit biomolecules and lead to beneficial biochemical reactions.
In the field of technology, there are also extraordinary performance. Can be used as a herbicide or weeding, its characteristics, In this way, 2,3,4-trifluorophenylacetonitrile has a significant position in the field of multiple applications, and it is also important for chemical research.
Research & Development
The research and development of 2,3,4-trifluorophenylacetonitrile
There are chemical substances 2,3,4-trifluorophenylacetonitrile, and our generation is a chemical researcher to explore its research and development. This substance has great potential in the field of organic synthesis. Its unique chemical structure, containing fluorine atoms and nitrile groups, endows special reactivity and properties.
At the beginning of the research, focus on the synthesis path. After repeated experiments, an efficient synthesis method was optimized to improve yield and purity. During the process, the reaction conditions were carefully regulated, and the temperature and catalyst dosage were carefully considered to strive for the best effect.
At the development level, it has emerged in the research and development of medicine. It can be used as a key intermediate to participate in the construction of a variety of drug molecules, or it is expected to give birth to new specific drugs. Industrial production has also attracted attention. While expanding the scale, it pays attention to environmental protection and cost control, and aims to promote this chemical from the laboratory to a wide range of applications in a green and sustainable way, contributing to the progress of the chemical field.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of toxicants is also an important matter. Today, when it comes to 2,3,4-Trifluorobenzeneacetonitrile this substance, the study of its toxicity should not be ignored.
This substance is unique among chemical substances. Its toxicological investigation should be done from multiple paths. Or observe the path of its entry into the body, through the mouth, through the skin or breathing; and examine its transformation in the body, the meridians of the viscera involved, and biochemical changes.
In the past, there were animals as test subjects, and observe the differences in their body shape, behavior, and viscera functions affected by this substance. It is also studied its harm to the environment, between water, soil, plants and trees, to observe the changes in its life.
However, the research on toxicity is not achieved overnight, and it needs to be accumulated over time and cautious. To obtain detailed results, to show the whole picture of toxicity 2,3,4 - Trifluorobenzeneacetonitrile, to build a solid foundation for the chemical industry, the safety of people's livelihood, to avoid the harm of toxins, and to protect the well-being of the public.
Future Prospects
I have tried to study chemical things, and now I will talk about 2,3,4 - Trifluorobenzeneacetonitrile this product. Looking at it, it is specific, and it seems to have infinite potential in the way of organic synthesis. Although it may not be fully capable at present, I look to the future, and I believe it will shine.
The field of chemistry is constantly new and changing, and the research of new things is the source of progress. 2,3,4 - Trifluorobenzeneacetonitrile may be the foundation for the creation of new drugs, but also the need for material innovation. In the future, the more advanced the technology and the deeper the understanding, it will emerge in the fields of medicine and materials, and become a strong aid to promote development. I look forward to it, hoping to see it shine in the future, be used by the world, and benefit all beings. This is the wish of my generation of chemical researchers.
Where to Buy 2,3,4-Trifluorobenzeneacetonitrile in China?
As a trusted 2,3,4-Trifluorobenzeneacetonitrile manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,3,4-Trifluorobenzeneacetonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,3,4-trifluorophenylacetonitrile?
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1. Pharmaceutical field
This substance is quite effective in medicine. It can help doctors heal many diseases, such as relieving discomfort in the body and inhibiting some inflammation. In drug processing, it can be used as a key raw material blindly. After clever compatibility, it can be made into a good medicine for treating specific diseases and relieving the pain of patients.
2. Chemical field
In the chemical industry, 2%2C3%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF%E4%B9%99%E8%85%88 also has important uses. It can be used as a basic raw material for synthesizing a variety of chemical products, and can be converted into substances with different properties by chemical processes. Or it can be used to make special materials, such as chemical materials with specific stability or reactivity, to meet the needs of different aspects of chemical production.
3. Scientific research
In the way of scientific research, this substance is also an important research object. Scholars can explore new chemical pathways and reaction laws by studying its properties and reaction mechanisms. Its unique structure and characteristics may open new doors for scientific research, help researchers make new understandings and breakthroughs in chemistry, biology and other fields, and promote the continuous expansion of the boundaries of scientific knowledge.
4. Agriculture-related
In agriculture, 2%2C3%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF%E4%B9%99%E8%85%88 or can play a certain role. With appropriate treatment and application, it may be used to develop new pesticides or plant growth regulators. It is helpful for crop pest control or growth regulation, thereby improving crop yield and quality, and contributing to the development of agriculture.
What are the physical properties of 2,3,4-trifluorophenylacetonitrile?
2%2C3%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF%E4%B9%99%E8%85%88, it is an organic compound. Its physical properties are quite special, let me tell you one by one.
First of all, under normal temperature, this substance is mostly colorless to light yellow oily liquid, which has a certain transparency, just like the clear Joan liquid. Its smell is special, although not pungent and intolerable, it also has a unique smell, which can make people feel a little strange, but it is not a bad smell.
As for its melting point, the melting point is low, and it turns into a flowing state when it encounters a slightly higher temperature. The boiling point is relatively moderate, and within a certain temperature range, it can boil and turn into a gaseous state. This property makes it unique in specific environments and processes.
Solubility is also one of its important physical properties. In organic solvents, such as ethanol and ether, the 2%2C3%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF%E4%B9%99%E8%85%88 is quite easy to dissolve, just like salt dissolves in water, and the two blend seamlessly. However, in water, its solubility is very small, and the two seem to be distinct and difficult to miscible.
In terms of density, it is larger than water. If it is placed in one place with water, after standing, it will sink to the bottom of the water, like a stone abyss.
In addition, 2%2C3%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF%E4%B9%99%E8%85%88 still has a certain volatility. When exposed to air, it will slowly evaporate, and its molecules will gradually escape in the surrounding space. Therefore, when storing, it needs to be carefully sealed to prevent its escape.
These are the physical properties of 2%2C3%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF%E4%B9%99%E8%85%88, and their characteristics are of great significance in the fields of chemical industry and medicine.
What are the chemical properties of 2,3,4-trifluorophenylacetonitrile?
2%2C3%2C4-%E4%B8%89%E6%B0%9F%E8%8B%AF%E4%B9%99%E8%85%88%E7%9A%84%E5%8C%96%E5%AD%A6%E6%80%A7%E8%B4%A8%E5%A6%82%E4%B8%8B%EF%BC%9A
This substance is flammable and can react violently with oxygen under certain conditions, releasing a lot of heat and light, which is the basis for its potential application as a fuel. It has a certain volatility. At room temperature and pressure, some molecules are easy to leave the liquid surface and enter the gas phase, causing its odor to be detectable in the surrounding air.
In terms of solubility, it is soluble in most organic solvents such as ethanol and ether. Due to the principle of similar miscibility, its molecular structure is compatible with organic solvents. However, its solubility in water is limited, because its molecular polarity is quite different from that of water molecules.
Chemical stability is at a moderate level. Under normal conditions, it can exist stably for a period of time. However, when it encounters strong oxidants such as potassium permanganate, the structure is easily destroyed, oxidation reactions occur, and some chemical bonds in the molecule are broken and recombined. When it encounters strong acids and bases, reactions will also occur. Under acidic conditions, it may initiate the protonation of some functional groups in the molecule, changing the charge distribution and chemical activity of the molecule; under alkaline conditions, or reactions such as hydrolysis occur, resulting in the decomposition of the molecular structure.
Because it contains specific unsaturated bonds and functional groups, it has certain reactivity and can participate in addition reactions, such as addition to halogen elements, unsaturated bonds are opened, and halogen atoms are added to it, thereby realizing chemical structure modification of substances and synthesis of new compounds. It can also participate in the substitution reaction, allowing specific atoms or groups in the molecule to be replaced by other atoms or groups, enriching the variety of derived compounds and providing a variety of possibilities for the field of organic synthesis.
What are the synthesis methods of 2,3,4-trifluorophenylacetonitrile?
The synthesis of 2% 2C3% 2C4-tribromobenzoic acid is an important topic in the field of organic synthesis. The synthesis method is very particular, and now it is the way for you.
First, benzoic acid can be used as the starting material and obtained by bromination reaction. First, put the benzoic acid in a suitable reaction vessel, add an appropriate amount of solvent, such as glacial acetic acid, to help it dissolve and disperse. Then slowly add brominating reagents, such as bromine or N-bromosuccinimide (NBS). Bromine has high activity, and the reaction needs to be carefully controlled. If NBS is used as the bromine source, the reaction is relatively mild and easy to control. During the reaction, it is often necessary to add an initiator, such as benzoyl peroxide, to initiate the reaction. During the reaction process, temperature, reagent dosage and reaction time are all key factors. Generally speaking, the temperature should be maintained in a moderate range. If the temperature is too high, it may cause the formation of polybrominated products and affect the purity of the product; if the temperature is too low, the reaction rate will be slow and take a long time. After the reaction is completed, the product can be purified by extraction, washing, drying and recrystallization.
Second, it can also be synthesized with m-bromotoluene as raw material. M-bromotoluene is first oxidized to convert methyl into carboxyl groups. Commonly used oxidizing agents include potassium permanganate, potassium dichromate, etc. Under suitable alkaline conditions, potassium permanganate can oxidize the methyl of m-bromotoluene to carboxyl groups. During this reaction, it is necessary to pay attention to the pH value and temperature of the reaction system. After oxidation is completed, 2% 2C3% 2C4-tribromobenzoic acid can be obtained by appropriate acidification treatment. Subsequent separation and purification methods are also required to obtain high-purity products.
Third, start from the corresponding phenolic compounds. First protect the phenolic hydroxyl group to prevent it from interfering in the subsequent reaction. Then through a series of reactions such as bromination, deprotection and carboxylation, the structure of the target product is gradually constructed. Although this route is a little complicated, the substitution position of bromine atoms can be precisely controlled, which is conducive to improving the selectivity of the product. Each step of the reaction requires strict control of the conditions to achieve the ideal synthesis effect.
The above methods have their own advantages and disadvantages, and the appropriate synthesis path should be carefully selected according to the actual experimental conditions, raw material availability and product requirements.
What are the precautions for 2,3,4-trifluorophenylacetonitrile during storage and transportation?
2% 2C3% 2C4-trihydroxymethylaminomethane, also known as ammonium retardant acid, has many points to be paid attention to during storage and transportation.
When it is stored, the first environment is dry. This substance is water-absorbent. If the environment is humid, it is easy to cause it to get damp and agglomerate, which affects the quality and use effect. Therefore, it should be stored in a dry warehouse, and the humidity should be controlled at a low level.
Furthermore, the temperature should also be suitable. Excessive temperature may cause it to decompose and deteriorate, and too low temperature may affect its physical properties. Generally speaking, it should be stored in a cool environment, and the temperature should be 15-30 ° C.
Storage should also pay attention to isolation. It needs to be stored separately from oxidants, acids, etc. Because of its active chemical properties, contact with these substances or cause chemical reactions, which brings potential safety hazards.
During transportation, the packaging must be solid. Appropriate packaging materials should be used to ensure that it will not be damaged or leaked during handling, loading and unloading, and transportation bumps.
The means of transportation should also be clean. Avoid residual other chemicals from reacting with it, and prevent sun exposure, rain, and keep away from fires and heat sources during transportation.
The escort personnel also need to be professional. Familiar with the characteristics of 2% 2C3% 2C4-trihydroxymethylaminomethane, it can be properly disposed of in case of emergencies, and ensure the safety of transportation. Only in this way can the substance be stable and safe during storage and transportation.