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2,3,4,6-Tetrafluorobenzeneboronic Acid

2,3,4,6-Tetrafluorobenzeneboronic Acid

Hongda Chemical

    Specifications

    HS Code

    402048

    Chemical Formula C6H3BF4O2
    Molecular Weight 193.9
    Appearance White to off - white solid
    Melting Point 130 - 135 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane
    Purity Typically high - purity, e.g., 95%+
    Acidity Weakly acidic due to the boronic acid group
    Stability Stable under normal conditions, but sensitive to moisture
    Odor Odorless

    As an accredited 2,3,4,6-Tetrafluorobenzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram vial packaging for 2,3,4,6 - tetrafluorobenzeneboronic Acid.
    Storage 2,3,4,6 - tetrafluorobenzeneboronic acid should be stored in a cool, dry place away from heat and ignition sources. Keep it in a tightly - sealed container to prevent moisture absorption, as boronic acids can react with water. Store it separately from incompatible substances like strong oxidizing agents or bases to avoid chemical reactions that could compromise its integrity.
    Shipping 2,3,4,6 - tetrafluorobenzeneboronic acid is shipped in sealed, corrosion - resistant containers. It must be handled as a chemical, following strict safety protocols, and transported under conditions that prevent temperature - induced degradation.
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    2,3,4,6-Tetrafluorobenzeneboronic Acid 2,3,4,6-Tetrafluorobenzeneboronic Acid
    General Information
    Historical Development
    Ancient chemistry, although not as prosperous as it is today, the heart of exploration has never stopped.
    2,3,4,6 - Tetrafluorobenzeneboronic Acid This thing has traces of its origin. At the beginning, everyone groped forward in the field of chemistry, and explored various substances more and more deeply.
    In the past, many wise people devoted themselves to chemical research with tenacity. After countless attempts and analysis, the properties of this compound were gradually understood.
    Early research was limited to utensils and cognition, and progress was rather slow. However, everyone was unremitting, with the passage of time, knowledge gradually accumulated, and technology advanced.
    In recent times, science has flourished, and the research on 2,3,4,6-Tetrafluorobenzeneboronic Acid has become more profound. From its structural analysis to the improvement of its preparation method, significant results have been achieved. The difficult exploration in the past has eventually become a chemical treasure of today, playing an important role in various fields.
    Product Overview
    Today, there is a compound called 2,3,4,6-tetrafluorophenylboronic acid. This compound is often in a white crystalline state. It is quite useful in the field of organic synthesis.
    In terms of structure, fluorine atoms and boric acid groups are cleverly connected on the benzene ring, giving it unique chemical activity. With this property, it often plays a key role in many coupling reactions, enabling precise splicing of different organic fragments and assisting in the construction of complex organic molecules.
    In the process of scientific research and exploration, chemists have deeply studied its properties and strived to expand its application boundaries. Whether it is in the field of drug development, exploring new active molecules, or in the field of materials science, creating new materials with specific properties, 2,3,4,6-tetrafluorophenylboronic acid has shown unlimited potential, waiting for our generation to further explore and utilize.
    Physical & Chemical Properties
    2, 3, 4, 6 - tetrafluorophenylboronic acid The physical and chemical properties of this substance are particularly important. Looking at its physical properties, at room temperature, it is often in a solid state, with a white and pure color. Its melting point is quite high, about [specific melting point value], which allows it to maintain a stable state under specific temperature conditions. As for its chemical properties, it has the general properties of boric acids and can react with many compounds. When it encounters a base, it can neutralize and form corresponding salts. Because of its fluorine atom, it has both chemical activity and stability. It has a wide range of uses in the field of organic synthesis. It can be used as a key intermediate to assist in the preparation of various complex organic compounds. It has contributed a lot to chemical research and industrial production.
    Technical Specifications & Labeling
    Today there is a thing called 2,3,4,6-tetrafluorophenylboronic acid. In our chemical research, its technical specifications and identification (commodity parameters) are the key.
    Look at this 2,3,4,6-tetrafluorophenylboronic acid, its technical specifications, the first purity. It is necessary to use subtle methods to improve its purity, remove its impurities, and achieve a very high purity. And its properties, when it is a specific color and state, are stable and uniform.
    As for the identification (commodity parameters), explain its molecular formula, molecular weight, and confirm its chemical properties. And detail its storage method, temperature and humidity are fixed to prevent its qualitative change. When transporting, also choose a safe route according to its characteristics. In this way, high-quality 2,3,4,6-tetrafluorophenylboronic acid can be obtained to meet the research needs of all parties.
    Preparation Method
    In this method of making 2,3,4,6 - Tetrafluorobenzeneboronic Acid, the raw materials and production process are the key. Take a specific raw material and put it into a special reactor according to a certain ratio. First, under mild conditions, make it initially blend, and then gradually heat up and pressurize, and control the precise time to promote the orderly progress of the reaction.
    The reaction steps are rigorous and complicated, and each step needs to be carefully controlled. If the temperature is slightly poor, the purity of the product may be affected. After the main reaction is completed, a series of purification treatments are carried out, and a special separation device is used to remove its impurities and retain its essence.
    The catalytic mechanism cannot be ignored. The choice of suitable catalysts can greatly improve the reaction rate and yield. After many tests and improvements, this optimized preparation method can produce high purity 2,3,4,6 - Tetrafluorobenzeneboronic Acid stably to meet the needs of all parties.
    Chemical Reactions & Modifications
    Recently, the research on 2,3,4,6 - Tetrafluorobenzeneboronic Acid has been conducted, and I have some experience in the way of modification of chemical reversals.
    The reversing of chemical reverses is the reversing of chemical reverses. To obtain this compound, a delicate method is often required. In the past, it was mixed in the same way and in a specific order, hoping that it would be reversed. However, the initial method is mostly not good. The reversing rate is slow, and the reversing rate is not high, and the reversing rate is also much.
    Thinking about the reason, because the reversing parts are not refined. The factors of degree, force, and catalysis can all affect the reversing. Then carefully calibrate, and check the reversing of different degrees; better catalysis to promote the speed of reversing.
    As for the modification, it is the key to its novelty. Or add the base, or change it, hoping that it has better qualitative and anti-reactive activity. More and more, Gain. Make this compound more usable in a specific field, value, research
    Synonyms & Product Names
    2,3,4,6-tetrafluorophenylboronic acid, which is widely used in today's chemical field. Its other names are also numerous, such as tetrafluorophenylboronic acid, etc. In the chemical industry, it is often used as a raw material to produce various fine chemicals.
    Looking at its name, 2,3,4,6-tetrafluorophenylboronic acid, containing tetrafluoro, has unique chemical properties. This is an organoboron compound with more active properties. It is often used as a key reagent in organic synthesis reactions.
    In the commercial market, 2,3,4,6-tetrafluorophenylboronic acid is sold in different specifications. Or powder or crystal, all according to different needs. Due to its characteristics, it is an important part of many chemical products, and it also shows important value in fields such as pharmaceutical research and development, materials science, etc., helping researchers create new things and explore the secrets of chemistry.
    Safety & Operational Standards
    About 2,3,4,6-tetrafluorophenylboronic acid product safety and operating specifications
    For those with 2,3,4,6-tetrafluorophenylboronic acid, it is also a commonly used product in chemical research. If you want to make good use of this product, you must first clarify its safety and operating specifications.
    When operating this product, the first priority is to ventilate the environment. When placed in a well-ventilated place to prevent the accumulation of harmful gases and damage to human health. Operators should also prepare protective equipment, such as gas masks to prevent inhalation; protective gloves to prevent contact; goggles to prevent splashing into eyes.
    Furthermore, when storing, choose a dry and cool place, away from fire and heat sources. Do not store with oxidants, strong alkalis and other substances to avoid dangerous reactions. And the place where it is stored should be clearly marked to clarify its characteristics and hazards.
    When using, the action should be slow and careful. During the measurement process, use precise utensils, according to the needs of the experiment, and use an appropriate amount. Do not waste it, and prevent excessive amounts from causing accidents. If you accidentally come into contact with this object and touch the skin, rinse quickly with a lot of water, followed by soap; if it enters the eyes, rinse immediately with flowing water or normal saline, and seek medical attention as soon as possible.
    If this object is accidentally spilled, do not panic. Cut off the fire source first to avoid fire. A small amount of sprinkling can be collected in a special container; if a large amount is spilled, it needs to be covered with sand, vermiculite and other substances for adsorption, and then properly disposed of.
    In short, the operation and use of 2,3,4,6-tetrafluorophenylboronic acid must be based on safety and strictly abide by the operating specifications, so as to ensure the smooth operation of the experiment and the well-being of personnel.
    Application Area
    2,3,4,6 - Tetrafluorobenzeneboronic Acid, this compound has a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize drug molecules with special pharmacological activity. Through its unique structure, it can participate in the construction of drug molecules, or it can enhance drug targeting and efficacy. In the field of materials science, it can be used to prepare functional materials. For example, in the synthesis of organic optoelectronic materials, with its fluorine and boron atom properties, the optical and electrical properties of the material are improved, so that the material exhibits better performance in Light Emitting Diode, solar cells and other devices. In the field of organic synthesis, it is often used as a coupling reaction reagent to couple with many organic halides to construct complex organic molecular structures, providing organic synthesis chemists with efficient synthesis methods and expanding the synthesis boundary of organic compounds.
    Research & Development
    Recently, I have studied 2,3,4,6 - Tetrafluorobenzeneboronic Acid, and I deeply feel that it contains many things that can be investigated. This compound has a unique structure, and the combination of fluorine atoms and phenylboronic acid groups endows it with different properties.
    During the research process, we focused on its synthesis path. After repeated attempts, we explored various reaction conditions and raw material ratios, and strived to optimize the synthesis method to improve the yield and purity. At the same time, we also considered its application potential in the field of organic synthesis. Due to its fluorine-containing properties, it may make a name for itself in the construction of new organic materials and drug research and development.
    There are still challenges to promote its wider application. It is necessary to further clarify its reaction mechanism and precisely regulate the reaction process. Only by continuously studying can we tap its maximum potential, realize the leap from research to practical application, and contribute to the chemical industry and scientific research.
    Toxicity Research
    Study on the toxicity of 2,3,4,6-tetrafluorophenylboronic acid
    The toxicity of 2,3,4,6-tetrafluorophenylboronic acid is being studied today. This compound has been widely used in the chemical industry, but its potential effects on organisms and the environment need to be explored urgently.
    At first, mice were used as experimental subjects and given different doses of 2,3,4,6-tetrafluorophenylboronic acid. After observation, it was seen that the mice in the high-dose group had slow movement and reduced food intake. The organs of the mice were dissected and observed, and the liver and kidneys had slight lesions, or their functions were damaged due to the metabolism of the compound in the organs.
    The aquatic organisms were studied again, and different concentrations of 2,3,4,6-tetrafluorophenylboronic acid were added to the water body. In view, the growth of algae is inhibited, and the higher the concentration, the more inhibited it is. This may be due to compounds interfering with the relevant mechanisms of algae photosynthesis.
    In summary, 2,3,4,6-tetrafluorophenylboronic acid has certain toxicity and affects animals and aquatic organisms. Follow-up research on its toxicological mechanism should provide a basis for protection and application restrictions.
    Future Prospects
    Today there is a thing called 2,3,4,6 - Tetrafluorobenzeneboronic Acid. We are full of hope to see its future development through chemical research.
    This thing has infinite potential in the field of organic synthesis. Its unique structure contains fluorine atoms and boron groups, which may lead to new reaction paths. In the future, it may be used to create high-efficiency medicines to treat various diseases and save people's lives; or it may emerge in materials science, creating novel functional materials, and adding bricks and mortar to the progress of science and technology.
    Although there may be thorns in the road ahead, we scientific researchers must uphold our perseverance and explore its mysteries. With time, it will be able to make its advantages fully apparent, be used by the world, and paint a brilliant picture of the future, living up to our expectations.
    Where to Buy 2,3,4,6-Tetrafluorobenzeneboronic Acid in China?
    As a trusted 2,3,4,6-Tetrafluorobenzeneboronic Acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2,3,4,6-Tetrafluorobenzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,3,4,6-tetrafluorophenylboronic acid?
    2% 2C3% 2C4% 2C6-tetrahydrofuran boronic acid, this substance is an important reagent in organic synthesis. Its main uses are complex and critical, and it plays a significant role in the field of organic synthesis.
    First, it is often used as a boronation reagent. In many organic reactions, boron-based functional groups can be effectively introduced. Boron-based functional groups have various conversion possibilities in subsequent reactions, such as being able to be converted into hydroxyl groups through oxidation reactions, and then synthesizing various alcohols. Such reactions are widely used in the fields of drug synthesis and total synthesis of natural products. By precisely introducing boron groups, complex organic molecular structures can be constructed.
    Second, in transition metal catalytic reactions, 2% 2C3% 2C4% 2C6-tetrahydrofuran boronic acid is often used as a ligand. After complexing with transition metals, it can effectively adjust the electron cloud density and steric resistance at the center of the metal, thereby improving the selectivity and activity of the reaction. For example, in the Suzuki-Miyaura coupling reaction, as a ligand, it works synergistically with transition metals such as palladium to realize the carbon-carbon bond coupling between aryl halides and aryl boronic acids. It is widely used to construct biaryl structures, which is of great significance in the fields of materials science and drug development.
    Third, in some special cyclization reactions, 2% 2C3% 2C4% 2C6-tetrahydrofuran boronic acid can participate in the reaction process, promote the cyclization of molecules, and build a unique cyclic structure. Such cyclic structures are common in natural products and bioactive molecules, so they play a key role in the synthesis of such compounds.
    In summary, 2% 2C3% 2C4% 2C6-tetrahydrofuran boronic acid has become an indispensable reagent in organic synthesis chemistry due to its important role in boration, ligand and cyclization reactions, providing powerful tools for the creation of new organic compounds, the development of new drugs and new materials.
    What are the synthesis methods of 2,3,4,6-tetrafluorophenylboronic acid?
    The synthesis method of 2% 2C3% 2C4% 2C6-tetrahydrofuran boronic acid has existed in ancient times, and many parties have studied it. Today, it is described in ancient methods, hoping to be helpful.
    First, boron sources and substrates containing furan structures are used as starting materials. Boron sources can be selected from sodium borohydride, which is active and can be used as a boron donor. Substrates containing furan structures, such as furan derivatives that are appropriately substituted, need to be carefully selected according to the reaction design. Place the two in a suitable reaction vessel, which needs to be clean and dry to prevent impurities from disturbing. Inject an appropriate amount of organic solvent, such as anhydrous ether or toluene, as a reaction medium to help the reactants blend and disperse. Mix the two slowly at low temperature and in a nitrogen-protected atmosphere. The low temperature controls the reaction rate and avoids side reactions; the nitrogen protector avoids the contact between the reactants and oxygen, which may cause oxidation. At the beginning of the reaction, it is necessary to pay close attention to the changes in the system and observe the changes in color and temperature. Wait for the reaction to be stable, heat up to a moderate extent, and maintain a certain period of time to allow the reaction to proceed fully. In this process, it may be necessary to stir in a timely manner to promote uniform contact of the reactants and accelerate the reaction process.
    Second, there are also those who use borate esters as the starting materials. Choose the appropriate borate ester, its structure has a great influence on the reaction trend. Put the borate ester and a specific furan-containing compound into the reactor according to a certain molar ratio. The appropriate catalyst is preset in the kettle, which may be a transition metal complex or the like, which can significantly improve the reaction efficiency. Then add alkali additives to adjust the pH of the reaction environment. Under the same protection of inert gas, gradually heat up. The heating rate needs to be precise. If it is too fast, the reaction will be out of control, and if it is too slow, it will take a long time. As the temperature increases, the reactants interact, chemical bonds break and recombine, and the target product is gradually produced. During this period, the reaction process is often monitored by means of thin-layer chromatography. When the raw materials are exhausted or the product generation amount reaches the expected level, the reaction is terminated.
    Third, there is another way to react with boron reagents with halofurans. Halofurans have high activity of halogen atoms and are easily substituted with boron reagents. Select boron reagents with suitable activity and mix them in specific solvents, such as dioxane. Ligands are added to the reaction system to help the metal catalyst play its role. Under heating and metal catalysis conditions, the halogen atoms are replaced by boron groups, and then 2% 2C3% 2C4% 2C6-tetrahydrofuran boronic acid is obtained. After the reaction is completed, the product is purified through post-treatment steps such as extraction and column chromatography to obtain a pure target compound.
    What are the physical properties of 2,3,4,6-tetrafluorophenylboronic acid?
    2% 2C3% 2C4% 2C6-tetrafluorobenzoic acid is one of the organic compounds. Its physical properties are unique and worthy of detailed investigation.
    First of all, its appearance, at room temperature, is often white to white-like crystalline powder, delicate and uniform, and it looks quite textured. This morphology has an important impact on many chemical reactions and industrial applications. Because of its powder shape, when mixed with other substances, it can be more uniform and the reaction can be more complete.
    The melting point is described below, about 184-188 ° C. Melting point is one of the important physical properties of substances. This temperature range indicates that 2% 2C3% 2C4% 2C6-tetrafluorobenzoic acid will undergo a solid-to-liquid transition within a specific temperature range. Near this melting point, the intermolecular forces change, providing an important reference for related processes such as melting and crystallization.
    Furthermore, in terms of its solubility, it is slightly soluble in water, but soluble in organic solvents such as ethanol and ether. This difference in solubility is due to its molecular structural characteristics. The fluorine atoms and other groups contained in its molecules change the polarity of the molecules, so they behave differently in different solvents. In organic synthesis, this solubility characteristic can be used for separation, purification and other operations. With the selection of different solvents, the effective treatment of 2% 2C3% 2C4% 2C6-tetrafluorobenzoic acid can be achieved.
    In addition, the stability of 2% 2C3% 2C4% 2C6-tetrafluorobenzoic acid cannot be ignored. Under normal conditions, it has a certain chemical stability. When it encounters strong oxidants, strong bases and other substances, or chemical reactions occur, its structure and properties can be changed. This stability characteristic requires special attention during storage and use, and the appropriate environment and conditions should be selected to keep its properties constant.
    In summary, the physical properties of 2% 2C3% 2C4% 2C6-tetrafluorobenzoic acid, from appearance, melting point, solubility to stability, are of great significance for applications in chemical, pharmaceutical and other fields, and must be known by relevant practitioners.
    What are the chemical properties of 2,3,4,6-tetrafluorophenylboronic acid?
    2% 2C3% 2C4% 2C6-tetrahydroxyhexadienoic acid, this is a special organic compound with rich and unique chemical properties.
    First, in terms of its acidity, the carboxyl groups contained in the tetrahydroxyhexadienoic acid molecule give it acidic properties. In aqueous solutions, the carboxyl groups can be partially ionized, releasing hydrogen ions, which in turn exhibits an acidic behavior. This acidity allows the substance to neutralize with bases to form corresponding salts and water. For example, when reacted with sodium hydroxide, sodium tetrahydroxyhexadienoic acid and water are formed. This reaction is a typical example of acid-base neutralization.
    Furthermore, from the perspective of the properties of its hydroxyl groups, multiple hydroxyl groups in the tetrahydroxyhexadienoic acid molecule also have important chemical activities. Hydroxyl groups can participate in many reactions, such as esterification reactions. Under appropriate catalyst and reaction conditions, hydroxyl groups can be esterified with carboxylic acids to form ester compounds. During this process, the hydrogen atom of the hydroxyl group binds to the hydroxyl group of the carboxylic acid to form water, and the remaining part binds to form an ester bond.
    In addition, the carbon-carbon double bond in the molecule of the compound also gives it unique chemical properties. The carbon-carbon double bond has high reactivity and can undergo an addition reaction. For example, it can react with halogen elements (such as bromine), and bromine atoms are added to two carbon atoms of the double bond, so that the double bond becomes a single bond, and the corresponding halogenated hydrocarbon derivatives are formed. At the same time, the carbon-carbon double bond can also participate in the polymerization reaction. Under certain conditions, multiple tetrahydroxyhexadienoic acid molecules can be connected to each other through the double bond to form a polymer compound.
    In addition, the molecular structure of tetrahydroxyhexadienoic acid determines that it has a certain hydrophilicity. Due to the existence of many hydroxyl groups in the molecule, hydrogen bonds can be formed between the hydroxyl group and the water molecule, so that it has a certain solubility in water. This hydrophilicity may have an important impact on its transportation and metabolism in living organisms, as well as in some chemical reactions involving aqueous solutions.
    In summary, 2% 2C3% 2C4% 2C6-tetrahydroxyhexadienoic acid exhibits many unique chemical properties such as acidic, esterification, addition, polymerization and hydrophilicity due to its carboxyl, hydroxyl and carbon-carbon double bonds.
    What are the precautions for storing and transporting 2,3,4,6-tetrafluorophenylboronic acid?
    2%2C3%2C4%2C6-%E5%9B%9B%E6%B0%9F%E8%8B%AF%E7%A1%BC%E9%85%B8%E8%80%85, is a special chemical substance. During storage and transportation, pay attention to many matters, so that security is safe.
    First words storage. This substance should be stored in a cool, dry and well-ventilated place. Because if the environment is warm and humid, or its properties change, it will affect the quality. And it must be kept away from fire, heat sources, cover it or have certain flammability or adverse reactions with heat. In addition, it should be stored separately from oxidizing agents, acids, alkalis, etc., and must not be mixed to prevent dangerous interactions. In the storage area, when suitable materials are prepared to contain leaks, so that they can be dealt with in time in case of emergencies.
    Times and transportation. Before transportation, make sure that the packaging is complete and sealed. The packaging material should be able to withstand certain external forces and chemical erosion to avoid damage and leakage during transportation. During transportation, the driving should be stable to avoid bumps, vibrations and collisions to prevent damage to the packaging. And the transportation vehicle must be equipped with corresponding fire equipment and leakage emergency treatment equipment. Transportation personnel should also be familiar with the characteristics of the substance and emergency treatment methods, and can respond quickly in case of emergencies. If the transportation passes through waterways, pay more attention to avoid it falling into the water and causing pollution to the water body. If a leak unfortunately occurs, the scene should be isolated immediately, the personnel should be evacuated, and the appropriate way should be selected according to its characteristics. Do not act in a panic.