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2,3,4,5-Tetrafluoronitrobenzene

2,3,4,5-Tetrafluoronitrobenzene

Hongda Chemical

Specifications

HS Code

408128

Chemical Formula C6HNO2F4
Molecular Weight 195.07
Appearance Colorless to light yellow liquid
Boiling Point 182 - 184 °C
Melting Point 18 - 20 °C
Density 1.576 g/cm³
Solubility In Water Insoluble
Flash Point 77 °C
Vapor Pressure 0.36 mmHg (25 °C)
Refractive Index 1.450 (20 °C)

As an accredited 2,3,4,5-Tetrafluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250 - gram bottle packaging for 2,3,4,5 - tetrafluoronitrobenzene chemical.
Storage 2,3,4,5 - tetrafluoronitrobenzene should be stored in a cool, dry, well - ventilated area away from sources of heat, ignition, and direct sunlight. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents and reducing agents to prevent potential chemical reactions.
Shipping 2,3,4,5 - tetrafluoronitrobenzene is a chemical that may require special handling. Shipments should be in well - sealed, appropriate containers, following all relevant regulations for hazardous chemicals to ensure safe transportation.
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2,3,4,5-Tetrafluoronitrobenzene 2,3,4,5-Tetrafluoronitrobenzene
General Information
Historical Development
At the beginning of the 20th century, chemistry advanced and new substances appeared frequently. 2,3,4,5-tetrafluoronitrobenzene has also emerged. At the beginning, its preparation was difficult and the yield was quite low, so only a few talented people studied it.
In the middle period, chemical technology improved, the preparation method became better and the yield rose slightly, and it gradually attracted attention in the field of organic synthesis. Many skilled craftsmen used it as a basis to construct novel compounds and explore the unknown.
In modern times, technology took off, the preparation process was mature, the cost dropped sharply, and the output increased greatly. 2,3,4,5-tetrafluoronitrobenzene is widely used in medicine and materials, helping the industry to flourish. Its journey is like a pearl shining brightly, witnessing the brilliant evolution of chemistry.
Product Overview
2,3,4,5-tetrafluoro-nitrobenzene is an important intermediate in organic synthesis. Its color is light yellow to colorless, like a liquid, with a special smell. This substance is widely used in the chemical industry and can be used as a raw material for the synthesis of medicines, pesticides and dyes.
The preparation method is often obtained by the substitution reaction of fluoride and nitrobenzene derivatives. The reaction conditions need to be precisely controlled. The choice of temperature, pressure and catalyst is all related to the purity and yield of the product.
However, this substance has certain toxicity and irritation, and strict safety procedures must be followed when operating. Storage also needs to be cautious. It should be placed in a cool and ventilated place, away from fire and heat sources, to prevent danger.
Its value in scientific research and industrial production is quite high, and many researchers are working tirelessly to optimize its preparation process, improve product quality, expand the scope of application, and contribute to the development of the chemical industry.
Physical & Chemical Properties
2,3,4,5-tetrafluoronitrobenzene is a wonder of transformation. Its shape and color are colorless to light yellow liquid at room temperature, and it is clear in appearance. Its taste, specific gas, can be sensed by smell.
In terms of its physical properties, the melt is about -20 ° C, and the boil is between 186-188 ° C. The density is larger than that of water, about 1.74g/cm ³, and it is slightly soluble in water, but it is easily soluble in organic solvents, such as ethanol and ether.
Its chemical activity is active, and fluorine and nitro groups on the benzene ring make it easy to be attacked by nucleophiles. Nitro has strong electricity absorption, which reduces the density of electron clouds in the benzene ring, and the activity of fluorine atoms is abnormal. It can react with many reagents, such as sodium alcohol, amines, etc., to form a variety of derivatives. It is widely used in the production of medicines, pesticides, and dyes, and is actually an important substance in the chemical industry.
Technical Specifications & Labeling
For 2,3,4,5-tetrafluoronitrobenzene, the process specifications and identification (product parameters) are the key. The preparation of this product requires a precise method. First take an appropriate amount of raw materials, put them in a special utensil, control them at a suitable temperature, and use exquisite techniques to combine them. When reacting, carefully observe the changes to ensure that everything complies with the regulations.
As for the label, it must be named, its main ingredients are listed, and the exact content is recorded, and the signs of danger are marked, indicating a proper storage and transportation method. The process specifications are related to quality, and the logo is related to safety and practicality. The two complement each other and are indispensable to make 2,3,4,5-tetrafluoronitrobenzene a usable product to meet the needs of all parties.
Preparation Method
The method of preparing 2,3,4,5-tetrafluoronitrobenzene, the first raw material and production process. The selection of raw materials must be carefully reviewed, which is related to the purity and yield of the product. In the production process, the reaction step is very critical. First, a specific reactant is mixed in a certain ratio, and the initial reaction is initiated at a specific temperature and pressure. This step requires precise temperature control. If the temperature deviates, it may cause a cluster of side reactions.
After the initial reaction is completed, it is transferred to the follow-up reaction stage. The reaction conditions are skillfully adjusted to make the reaction proceed in the direction of generating the target product. At the same time, a suitable catalytic mechanism is constructed to improve the reaction rate and efficiency. The catalysts used need to be carefully screened to consider their activity, selectivity and stability. In this way, through various steps, relatively pure 2,3,4,5-tetrafluoronitrobenzene products can be obtained to meet the needs of industry or scientific research.
Chemical Reactions & Modifications
2,3,4,5-tetrafluoronitrobenzene is also an organic compound. Its chemical reaction and modification are the most important things for chemical researchers.
In the past, researchers wanted to explore the wonder of its reaction in order to modify its properties and make it suitable for use. The reaction of 2,3,4,5-tetrafluoronitrobenzene often involves nucleophilic substitution and the like. The fluorine atom on its benzene ring is quite active due to the absorption of nitro groups. Researchers often attack it with nucleophilic reagents, so that the fluorine atom is replaced by other groups in order to obtain a new product.
For the reason of modification, it also changes the reaction conditions, such as temperature and solvent. High temperature or strong polar solvents can often promote the speed of reaction and change the selectivity of the product. Or add a catalyst to reduce the energy barrier of the reaction and make the reaction easy. After various attempts, it is hoped that the product with better performance can be used in various fields such as medicine and materials.
Synonyms & Product Names
"On the same name and trade name of 2,3,4,5-tetrafluoronitrobenzene"
The chemical substance, 2,3,4,5-tetrafluoronitrobenzene, is unique. Its same name and trade name are related to the cognition of everyone in the industry. Looking at the statements of various parties, the same name is known to the academic community because of its chemical structure. The trade name is born due to the needs of business operation and market.
The use of the same name is to accurately convey the essence of the material, so that scholars can study and artisans can prepare it. Trade names are either novel or easy to remember, in order to show their characteristics and help marketing activities. For example, 2,3,4,5-tetrafluoronitrobenzene, under the same name, the trade name may be different due to the different uses and processes. However, both of them revolve around this thing, with the same name establishing their original, and the trade name expanding their use. For chemical research and industrial operation, the same name and the trade name complement each other and are indispensable to promote the cognition and application of 2,3,4,5-tetrafluoronitrobenzene.
Safety & Operational Standards
Specifications for the safety and operation of II, III, IV, V-tetrafluoronitrobenzene
Fu 2,3,4,5-tetrafluoronitrobenzene is an important substance in chemical research. Its special nature is related to the safety and effectiveness of the experiment. Therefore, those who operate it must understand its safety and operation specifications.
In terms of safety, this substance is dangerous. In case of open flame or hot topic, there is a risk of combustion and explosion. And its vapor and air can form an explosive mixture. In case of fire source, it is very harmful. The reason is to keep away from fire and heat source and keep well ventilated.
When operating, also need to be cautious. Operators should wear appropriate protective equipment, such as protective glasses, gloves and protective clothing, to prevent contact with skin and eyes. If accidentally touched, they should quickly rinse with plenty of water and seek medical attention in time.
Furthermore, the experimental site should be equipped with corresponding fire equipment and leakage emergency treatment equipment. In the event of a leak, personnel from the leakage contaminated area must be quickly evacuated to a safe area, and isolated, strictly restricting access. Emergency personnel need to wear self-contained positive pressure breathing apparatus, wear anti-toxic clothing, and do not let the leakage come into contact with combustible substances. In the event of a small amount of leakage, it can be absorbed by inert materials such as sand and vermiculite; in the event of a large amount of leakage, a dike or a pit should be built for containment, and covered with foam to reduce steam disasters.
When taking this substance, the control of the amount is also critical. When measured accurately according to the needs of the experiment, avoid waste and prevent danger due to excessive amounts. After operation, the utensils used should be cleaned in time and stored properly for later use.
In short, in the research and use of 2,3,4,5-tetrafluoronitrobenzene, safety and standardized operation are of paramount importance. Operators need to be vigilant at all times and act according to the rules in order to achieve the purpose of the experiment and ensure the safety of themselves and the environment.
Application Area
2,3,4,5-tetrafluoronitrobenzene is widely used in the field of chemical industry. It is a genus of pharmaceutical synthesis and can be a key intermediate. With its unique structure, it can react with many reagents to derive a variety of specific drug ingredients, which can help the research and development of medicine.
In the field of materials science, it also has its own uses. It can be prepared by specific processes and integrated into new materials, giving materials special properties, such as enhancing their stability and weather resistance, etc., to expand the application range of materials.
In the process of pesticide creation, 2,3,4,5-tetrafluoronitrobenzene is also indispensable. It can be skillfully chemically converted into highly efficient and low-toxic pesticide active ingredients, protecting agricultural production and ensuring a bumper harvest, making great contributions to agricultural development. All of these are manifested in the importance of various application fields.
Research & Development
In recent years, those who study chemical substances should pay attention to this product in 2, 3, 4, 5 - Tetrafluoronitrobenzene. It has unique properties and may be of great use in various fields.
We have studied its quality and explored its synthesis method. At first, with conventional techniques, the effect was not significant. After repeated research, we changed the material mix and adjusted the temperature and pressure of the reaction, and gradually obtained a better method. The rate of synthesis has also increased from a small number at the beginning to a considerable number.
Looking at its application, it can be used as a key intermediate in the production of medicine to help the formation of new drugs. In the field of materials, it can also add its characteristics to make the material better.
Looking to the future, the development of 2, 3, 4, 5 - Tetrafluoronitrobenzene has infinite potential. We should continue to study, expand its application, and promote its luminous energy in more fields, so as to contribute our wisdom and strength to the advancement of chemistry and the benefit of people's livelihood.
Toxicity Research
Study on the toxicity of 2,3,4,5-tetrafluoronitrobenzene
Recent research on chemical products, 2,3,4,5-tetrafluoronitrobenzene, has gradually attracted the attention of the public. Although it is available in various industries, the study of toxicity should not be ignored.
Fu 2,3,4,5-tetrafluoronitrobenzene, its strong nature, touch, smell, can be harmful. Tasted in guinea pigs, exposed to this thing, hair erect and irritable, rapid breathing and chaotic, it can be seen that it is harmful to living things. It enters the body again, or attacks the liver and spleen, or disturbs qi and blood. Looking at the changes of various cells, the metabolism is chaotic and the activity is reduced, which is enough to prove its toxicity.
And this thing also leaves hidden dangers in the environment. If it is scattered in the air, it will pollute the air; if it enters the water, it will harm the aquarium. Although the amount is small, it will add up to a lot, which is not a shallow disaster. It is the most important task today to study its toxicity, control its use, and prevent it from dispersing. The industry of the chemical industry, when used properly, to avoid the harm of life and the environment, is the way to last for a long time.
Future Prospects
2,3,4,5-tetrafluoronitrobenzene is a chemical product that we have dedicated ourselves to studying. Looking at its current situation, although it has been achieved, there is still a lot of room for future expansion.
In the way of performance improvement, new synthesis processes can be explored to achieve better purity and quality. If so, it can be widely used in the field of high-end manufacturing, such as the preparation of electronic devices and pharmaceuticals, which may give a new appearance.
On the market, its application is not widely used at present, but looking forward to the future, with the rapid advancement of science and technology, emerging industries are booming, and their demand will be like bamboo shoots. We should make early plans to expand production capacity and optimize supply to meet future needs.
In the path of scientific research, we should also unswervingly study its materialization, explore its undiscovered capabilities, and hope to draw a gorgeous picture for its future with new discoveries and new applications. In this way, the future of 2,3,4,5-tetrafluoronitrobenzene will be like the rising sun, with a bright future.
Where to Buy 2,3,4,5-Tetrafluoronitrobenzene in China?
As a trusted 2,3,4,5-Tetrafluoronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,3,4,5-Tetrafluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,3,4,5-tetrafluoronitrobenzene?
2% 2C3% 2C4% 2C5-tetrahydroxyphenylalanine, also known as L-dopa (L-DOPA), its main uses are as follows:
L-dopa is a precursor drug of dopamine and is effective in the treatment of Parkinson's disease. Parkinson's disease is caused by the progressive degeneration of dopaminergic nerve cells in the substantia nigra, which triggers a decrease in dopamine secretion. L-dopa can be converted into dopamine in the brain through the action of dopa decarboxylase through the blood-brain barrier, thereby supplementing the deficiency of dopamine in the brain, effectively improving many symptoms such as tremor, myotonia, and motor retardation in Parkinson's disease patients, and improving patients' ability to take care of themselves and quality of life.
Furthermore, L-dopa is also used in the treatment of hepatic encephalopathy. The pathogenesis of hepatic encephalopathy is related to the imbalance of neurotransmitters in the brain caused by elevated blood ammonia. After L-dopa is converted into dopamine in the brain, it can adjust neurotransmitters in the brain, which can help improve the psychoneurological symptoms of patients with hepatic encephalopathy, and promote the recovery of patients' consciousness and cognitive function.
In addition, in the field of medical research, L-dopa, as an important bioactive substance, helps scientists to deeply explore the pathogenesis of neurological diseases and develop new therapeutic drugs and methods.
"Tiangong Kaiwu" was written in Chongzhen ten years in the Ming Dynasty. Although there was no relevant record of 2% 2C3% 2C4% 2C5-tetrahydroxy phenylalanine at that time, if there was such content in the book, it might be described as follows: "2% 2C3% 2C4% 2C5-tetrahydroxy phenylalanine is of great use in the medical tract. It can cure the disease of tremor and convulsion, and the patient's limbs tremble and move slowly. This medicine enters the body and can be turned into dopamine, which can replenish the lack in the brain, make the limbs normal and facilitate movement. It can also be used for diseases of liver syndromes, and make the mind clear. And it is also a key thing for doctors to research the root cause of the disease and create new drugs, which is of great help."
What are the physical properties of 2,3,4,5-tetrafluoronitrobenzene?
2% 2C3% 2C4% 2C5-tetrafluorobenzyl ether, its physical properties are quite impressive. The color state of this substance is often in the form of a colorless and transparent liquid, and the appearance is clear, like a clear spring, without the slightest noise disturbing the eyes. Its quality is pure and natural.
Smell its smell, many of which have a weak and special fragrance, not pungent and intolerable, but seemingly absent, lingering in the nose, not boring, but feeling a little fresh.
As for its density, it is slightly heavier than that of common liquids. When placed in the hand, you can feel its sinking state, as if it contains endless mysteries. And its solubility is also unique, in many organic solvents, such as alcohols, ethers, etc., can be well miscible, just like water and milk blend, seamless.
Its boiling point is also an important physical property. Under specific pressure conditions, it can reach a certain temperature and boil and transform into a gaseous state. The value of this boiling point plays a key role in the separation and purification of the substance, like a precise beacon, guiding the direction of operation.
Furthermore, the melting point cannot be ignored. When the temperature drops to a certain value, the substance condenses from a liquid state to a solid state, like a sleeping spirit, waiting for the right temperature to wake up. The characteristics of this melting point need to be properly considered during storage and transportation to ensure the stability of its form.
These various physical properties are intertwined to outline the unique physical appearance of 2% 2C3% 2C4% 2C5-tetrafluorobenzyl ether, which lays a solid foundation for its application in many fields such as chemical industry and medicine.
What are the chemical properties of 2,3,4,5-tetrafluoronitrobenzene?
The chemical properties of 2% 2C3% 2C4% 2C5-tetraallyl silicon are as follows:
This substance has a unique chemical activity. In its molecular structure, the presence of allyl gives it active reactivity. Allyl is rich in electrons and easily participates in various electrophilic reactions. In case of electrophilic reagents, allyl double bonds can provide electrons, and an addition reaction occurs. It can combine with many electrophiles, such as hydrogen halides and halogens, to form new derivatives.
Furthermore, 2% 2C3% 2C4% 2C5-tetraallyl silicon has multiple allyl groups connected around the silicon atom, which affects the electron cloud density of the silicon atom. Silicon atoms can be used as a reaction check point to participate in some reactions involving the formation or breaking of silicon-carbon bonds. Under appropriate conditions, silicon-carbon bonds can be cleaved and replaced with other compounds containing active groups, resulting in the construction of more complex organosilicon structures.
Due to the spatial distribution of multiple allyl groups, 2% 2C3% 2C4% 2C5-tetraallyl silicon also has special performance in polymerization reactions. Allyl double bonds can undergo free radical polymerization under the action of initiators, or participate in some synergistic polymerization reactions to form polymeric materials with special structures and properties, which may have potential applications in the field of materials science.
Because of its active chemical properties, it is necessary to pay attention to environmental conditions when storing and using. Avoid contact with strong oxidants, strong acids and alkalis and other substances that are prone to violent reactions to prevent dangerous chemical reactions.
What are the synthesis methods of 2,3,4,5-tetrafluoronitrobenzene?
There are various ways to synthesize 2% 2C3% 2C4% 2C5-tetrafluorobenzyl ether.
First, it can be formed by the interaction of halogenated aromatics with fluorinated alkoxides under appropriate catalyst and reaction conditions. Take halogenated aromatics, place them in a reactor, and add an appropriate amount of alkali, such as potassium carbonate, sodium carbonate, etc., to create a suitable alkaline environment. Then add fluorine-containing alkoxides, such as potassium tetrafluorobenzyl alcohol or sodium tetrafluorobenzyl alcohol, stir well, and heat up to a certain temperature, usually between 60 and 120 ° C. The reaction lasts for several hours, depending on the specific reaction substrates and conditions, to achieve nucleophilic substitution reaction. The halogen atom is replaced by tetrafluorobenzyl oxide, so as to obtain the target product 2% 2C3% 2C4% 2C5 -tetrafluorobenzyl ether.
Second, the phenolic compound and tetrafluorobenzyl halide are used as raw materials and prepared by the Williamson ether synthesis method. First, the phenolic compound is reacted with a base to transform the phenolic hydroxyl group into a phenoxy anion to enhance its nucleophilicity. After that, tetrafluorobenzyl halide, such as tetrafluorobenzyl chloride or tetrafluorobenzyl bromide, is added in a suitable organic solvent, such as N, N-dimethylformamide, acetonitrile, etc., and the reaction is heated. The temperature is controlled at about 50-100 ° C. The phenoxy anion attacks the carbon atom attached to the halogen atom of the tetrafluorobenzyl halide, and the halogen ion leaves to form 2% 2C3% 2C4% 2C5-tetrafluorobenzyl ether.
Third, the transition metal catalytic coupling reaction is used to synthesize. Select suitable transition metal catalysts, such as palladium, copper and other catalysts, ligands such as phosphine ligands or nitrogen heterocyclic carbene ligands, and place halogenated aromatics, fluoroalcohols and bases in the reaction system. Under the protection of inert gas, heated to a specific temperature, such as 80-150 ° C, with the help of the catalytic activity of transition metals, the coupling reaction of halogenated aromatics and fluoroalcohols is promoted, and a carbon-oxygen bond is formed to form 2% 2C3% 2C4% 2C5-tetrafluorobenzyl ether.
The above synthesis methods have their own advantages and disadvantages. In practical application, the appropriate method needs to be carefully selected according to the availability of raw materials, cost, reaction conditions and purity of target products.
What are the precautions for storing and transporting 2,3,4,5-tetrafluoronitrobenzene?
2% 2C3% 2C4% 2C5-tetraallyl silicon requires attention to many matters during storage and transportation. When this object is stored, the first environment is dry and well ventilated, because it is easy to deteriorate due to humid gas, and the occlusion may cause the accumulation of dangerous gases, endangering safety. Furthermore, the temperature should be controlled within a specific range. Excessive temperature may promote its chemical reaction, causing instability; too low temperature may also affect its physical properties.
As for the transportation stage, the packaging must be strong and tightly sealed. To prevent vibration and collision from causing damage to the package and leakage of tetraallyl silicon. The means of transportation must also be clean and free of impurities to avoid impurities mixing in and affecting its quality. At the same time, transportation personnel should be familiar with its characteristics and emergency response methods. If there is a leak on the way, they can respond quickly and properly.
In addition, whether it is storage or transportation, keep away from fire sources, heat sources and oxidants. Tetraallyl silicon has a certain chemical activity. In case of fire, high temperature or oxidant, it may cause violent reactions, such as combustion and explosion, which will cause major disasters. Therefore, the entire storage and transportation process needs to strictly follow relevant specifications and requirements to ensure personnel safety and material quality.