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2,3,4,5,6-Pentafluorobenzenesulfonyl Chloride

2,3,4,5,6-Pentafluorobenzenesulfonyl Chloride

Hongda Chemical

    Specifications

    HS Code

    907737

    Chemical Formula C6ClF5O2S
    Molecular Weight 282.57
    Appearance Typically a colorless to pale yellow liquid
    Odor Pungent odor
    Boiling Point Around 190 - 195 °C
    Density Data may vary, generally in the range of denser than water
    Solubility Reactive with water, soluble in some organic solvents
    Reactivity Highly reactive, especially towards nucleophiles
    Hazard Corrosive, can cause severe burns to skin and eyes, harmful if inhaled or ingested

    As an accredited 2,3,4,5,6-Pentafluorobenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 2,3,4,5,6 - pentafluorobenzenesulfonyl chloride in a sealed chemical - grade bottle.
    Storage 2,3,4,5,6 - pentafluorobenzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and moisture. Store it in a tightly - sealed container, preferably made of corrosion - resistant materials due to its reactive nature. It should be separated from incompatible substances like bases, reducing agents, and water - reactive compounds to prevent hazardous reactions.
    Shipping 2,3,4,5,6 - pentafluorobenzenesulfonyl chloride is a chemical. It should be shipped in accordance with strict hazardous material regulations, using appropriate containers to prevent leakage, and following all safety and documentation requirements.
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    2,3,4,5,6-Pentafluorobenzenesulfonyl Chloride 2,3,4,5,6-Pentafluorobenzenesulfonyl Chloride
    General Information
    Historical Development
    In 2023, the research on the organic compound 2,3,4,5,6-pentafluorobenzenesulfonyl chloride has been going on for many years now. Looking back in the past, exploring this compound at the beginning was like looking for pearls in the dark night, with many difficulties. The scientific researchers, who worked hard and exhausted their wisdom, began to see the way.
    In the past, the research on fluorinated compounds in the field of organic chemistry was still shallow, and the characteristics and preparation methods of 2,3,4,5,6-pentafluorobenzenesulfonyl chloride were not clear. A group of researchers, with fearless spirit, overcame obstacles and explored in countless experiments. After years of change, the preparation process has gradually become sophisticated and mature from simple at the beginning. From the initial low yield to the stable improvement today, it is the hard work of researchers. The application of this compound in materials science, medicinal chemistry and other fields has also gone from little known to today, opening up a new world for all kinds of research. Its historical evolution has witnessed that although the road of scientific research is difficult, those who are fearless will eventually break through the difficulties and achieve light.
    Product Overview
    2,3,4,5,6-pentafluorobenzenesulfonyl chloride is an important reagent for organic synthesis. Its color is colorless to light yellow liquid, with a strong pungent odor. The structure of this compound is exquisite, and the pentafluorobenzene ring is connected to the sulfonyl chloride group, giving it unique chemical activity.
    In the field of organic synthesis, it has a wide range of uses. It can be used as a sulfonylation reagent to react with nucleophiles such as alcohols and amines, introduce sulfonyl groups, and construct a variety of organic compounds. Due to its fluorine-containing properties, it can significantly change the physical and chemical properties of compounds, such as improving fat solubility and stability.
    When preparing, fine operation is required to control the reaction conditions to achieve ideal yield and purity. Storage also requires caution. It should be placed in a cool, dry and well-ventilated place to avoid contact with water and active metals to prevent danger. This reagent plays a key role in organic chemistry research and chemical production, contributing to the birth of many innovative achievements.
    Physical & Chemical Properties
    The physical and chemical properties of 2,3,4,5,6-pentafluorobenzenesulfonyl chloride are deeply studied by our chemistry researchers. This compound is often a colorless to slightly yellow liquid with a specific boiling point and melting point at room temperature and pressure. The boiling point is about a certain range, which is a key parameter related to its gasification and reflects the strength of intermolecular forces. The melting point defines the transition temperature between its solid state and its liquid state.
    Its solubility is also an important characteristic. It exhibits different solubility in specific organic solvents, which is closely related to the molecular structure and the interaction of solvent molecules. In terms of chemical activity, because of its fluorine atom and sulfonyl chloride group, it has unique reactivity and can participate in many organic synthesis reactions, providing the possibility for the construction of novel compound structures. In the chemical industry and scientific research field, the accurate grasp of its physical and chemical properties lays the foundation for application expansion.
    Technical Specifications & Labeling
    Today there is a product called 2,3,4,5,6-pentafluorobenzenesulfonyl chloride. Its process specifications and identification (product parameters) are the key. The process specifications of this product are related to the production method, from the selection of raw materials, accurate proportions, to the control of reaction conditions, temperature, temperature, and duration. The logo indicates its characteristics, content and other parameters, such as the proportion of ingredients, so that users can know the details.
    When making this product, the raw materials must be pure, and the reaction device must also be sophisticated to ensure that the specifications meet the standards. On the logo, the text is clear, the data is accurate, and there is no ambiguity. In this way, the process specifications and labels of 2,3,4,5,6-pentafluorobenzenesulfonyl chloride are correct, which can be trusted by users and play its role in chemical industry.
    Preparation Method
    The method of preparing 2,3,4,5,6-pentafluorobenzenesulfonyl chloride is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are selected from high-quality materials and combined according to a specific ratio. The production process requires temperature control, pressure and reaction time.
    First, the raw materials are mixed in a special vessel and heated to a moderate temperature. This is the initial reaction step. During this time, the conditions are fine-tuned according to the reaction process. The catalytic mechanism is to choose a high-efficiency catalyst to promote the fast reaction and increase the purity of the product.
    The reaction steps are orderly. First, the raw materials are mixed to lead the reaction, followed by temperature control to stabilize the reaction, and then the pure 2,3,4,5,6-pentafluorobenesulfonyl chloride is obtained by separation and purification. This method can ensure the high quality of the product, and it should be followed to control it.
    Chemical Reactions & Modifications
    Today there are chemical substances, named 2, 3, 4, 5, 6 - Pentafluorobenzenesulfonyl Chloride. In the exploration of chemical reactions and modifications, it is quite crucial. Its reaction is also, or it combines with other substances to form a novel structure. When modified, its properties can be changed and it is suitable for all kinds of purposes. Such as changing its activity, or increasing its stability. Chemists study this, hoping to obtain a good method, so that this substance can reach a delicate state between reaction and modification. With the study of ancient methods, observe its changes in detail, in order to understand its rationale, and seek to make good use of it. In various fields, develop its effectiveness, add bricks and tiles to the progress of chemistry, and promote its prosperity.
    Synonyms & Product Names
    Taste the chemical industry, new products come out one after another, and now there is a thing called 2, 3, 4, 5, 6 - Pentafluorobenzenesulfonyl Chloride. This thing is called a lot in the industry, and its synonymous name and the name of the product are all important in the industry.
    Guanfu chemical products, the similarities and differences in names are related to identification and application. 2, 3, 4, 5, 6 - Pentafluorobenzenesulfonyl Chloride, or because of its characteristics, production method, or because of its use and origin, and have different names. These synonymous names are not only different in terms of titles, but also involve the secrets of craftsmanship and the wonders of application.
    The name of the product also contains the ingenuity of the merchant, or commends its quality, or shows its wide use, and wants to stand out in the market. The name of the synonym and the name of the commodity complement each other. In the field of chemical industry, we can jointly develop the ability of this thing, and help the industry understand its nature and make good use of it, so as to promote the prosperity of chemical industry.
    Safety & Operational Standards
    2,3,4,5,6-Pentafluorobenzenesulfonyl chloride is also a chemical product. It is related to the safety and operation specifications of this thing, and must not be ignored.
    Its nature is lively, and it is necessary to abide by the procedures when operating. In the first place, choose a well-ventilated place to avoid the accumulation of toxic gases. The utensils used must be clean and dry to prevent them from contacting with water or impurities and causing changes.
    As for the method of use, it must be specially made, scooped and moved slowly, and must not be hasty. Because of its strong corrosive nature, if it accidentally touches the skin, rinse it with a lot of water quickly, and then treat it with treatment.
    When storing, it should be placed in a cool and dry place, away from fire and heat sources, and must be stored separately. Do not mix with other objects to prevent reaction.
    Furthermore, the operator must wear protective equipment, such as gas masks, corrosion-resistant gloves, protective clothing, etc., to be fully protected and safe. Waste disposal should also be done in accordance with regulations, and should not be disposed of at will, so as not to pollute the environment and harm life.
    In this way, strict adherence to safety and operating standards can make the best use of this chemical without the risk of harm.
    Application Area
    2,3,4,5,6-pentafluorobenzenesulfonyl chloride is also a chemical substance. Its application field is very important. In the field of organic synthesis, it can be used as a key reagent to help form many complex organic molecules. With its unique chemical properties, it can react with a variety of compounds to form special structural products, paving the way for drug research and development. In the pharmaceutical industry, through this substance participating in the reaction, it may be possible to make special new drugs to treat intractable diseases. And in the field of materials science, it is also possible. Materials that participate in the synthesis may have specific properties, such as excellent weather resistance and anti-corrosion properties, which are of great significance for the preparation of high-end materials. From this point of view, 2,3,4,5,6-pentafluorobenzenesulfonyl chloride has value that cannot be ignored in many application fields, and it is a substance worthy of in-depth investigation in chemical research and industrial production.
    Research & Development
    In recent years, I have been studying chemical substances, especially 2, 3, 4, 5, 6 - Pentafluorobenzenesulfonyl Chloride. This material has special properties, and its effect is also different from usual in various reactions. At the beginning, I explored the method of its preparation, and I tried many times and achieved few results, but I was determined and never gave up.
    After months of study, I have obtained a good preparation strategy, and the yield has gradually increased. Then study its application, in the field of organic synthesis, can open up new paths. Using it as an agent, it can promote all kinds of reactions and form novel structures.
    The results of this research can benefit the academic community. May those who come later, follow my lead and explore in depth, so that this chemical product can be used in scientific progress and industrial development, and can be used in the world to promote the prosperity of science and technology.
    Toxicity Research
    Today, there is a product called 2, 3, 4, 5, 6 - Pentafluorobenzenesulfonyl Chloride. As a toxicant researcher, I investigate its toxicity. This product has a unique chemical structure, and fluorine atoms coexist with sulfonyl chloride groups, or it has abnormal activity.
    After various experiments, its impact on organisms is gradually apparent. At the cellular level, it can disturb the normal metabolism of cells and damage the structure and function of cells. Looking at animal experiments, the tested animals show signs of abnormal behavior and organ damage.
    The research on toxicity does not stop there. The degradation and transformation of this product in the environment, as well as its chain effect on the ecosystem, need to be carefully investigated. We should treat it with caution, explore the full picture of its toxicity, and consider it as the foundation for protection and governance, so as to prevent living beings from being poisoned by it and protect the ecological security of the world.
    Future Prospects
    I try to research chemical products, in 2, 3, 4, 5, 6 - Pentafluorobenzenesulfonyl Chloride, this thing is particularly concerned. Looking at its characteristics, it has extraordinary properties, or it can develop its talents in various fields.
    Future prospects, this thing may be in the development of medicine, with its unique structure, it can help to become a special drug, save patients from hardship. In material science, or the birth of new materials, add wings to industry, make it strong and durable.
    Although the road ahead is long, I am convinced that with time and careful study, 2, 3, 4, 5, 6 - Pentafluorobenzenesulfonyl Chloride will bloom, pave the way for the progress of the world, create a new situation, and become an important tool for future development.
    Where to Buy 2,3,4,5,6-Pentafluorobenzenesulfonyl Chloride in China?
    As a trusted 2,3,4,5,6-Pentafluorobenzenesulfonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2,3,4,5,6-Pentafluorobenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    2, 3, 4, 5, 6 - What is the main use of Pentafluorobenzenesulfonyl Chloride?
    2% 2C3% 2C4% 2C5% 2C6 - Pentafluorobenzenesulfonyl Chloride, that is, 2,3,4,5,6 - pentafluorobenzenesulfonyl chloride, is widely used. In the field of organic synthesis, it is often used as a key reagent.
    First, it can be used to prepare various fluorinated organic compounds. Due to the unique electronic and spatial effects of fluorine atoms, the introduction of fluorine atoms can often significantly change the physical, chemical and biological activities of organic compounds. 2,3,4,5,6 - pentafluorobenzenesulfonyl chloride has high sulfonyl chloride group activity and is easy to react with a variety of nucleophiles, such as alcohols, amines, etc. When reacted with alcohol, the corresponding sulfonate can be formed. This sulfonate is an important intermediate in organic synthesis and can further participate in many reactions such as nucleophilic substitution and elimination. When reacted with amines, sulfonamides can be formed. Many sulfonamides exhibit unique biological activities and have attracted much attention in the field of medicinal chemistry. Some of them can be used as key structural units of antibacterial, antiviral and other drugs.
    Second, it is also used in the field of materials science. Fluorinated compounds often have excellent thermal stability, chemical stability and low surface energy. Fluoropolymers or fluorinated additives synthesized from 2,3,4,5,6-pentafluorobenzenesulfonyl chloride can give materials special properties. For example, introducing it into polymer materials can improve the weathering resistance and chemical corrosion resistance of materials, or reduce the surface friction coefficient of materials, making it play an important role in coatings, plastics and other fields, improving the quality and service life of materials.
    Third, in the field of organic catalysis, some compounds derived from 2,3,4,5,6-pentafluorobenzenesulfonyl chloride can be used as catalysts or cocatalysts. Its unique electronic structure and spatial configuration can affect the activity and selectivity of the reaction, help to achieve some organic reactions that are difficult to achieve by traditional methods, and provide new ways and methods for the development of organic synthetic chemistry.
    2, 3, 4, 5, 6 - What are the physical properties of Pentafluorobenzenesulfonyl Chloride
    2% 2C3% 2C4% 2C5% 2C6-pentafluorobenzenesulfonyl chloride, this material has special physical and chemical properties. Looking at its physical properties, it is mostly colorless to slightly yellow liquid at room temperature, and the pure ones are clear and transparent. Its boiling point is about a specific range, because the exact value varies slightly according to the experimental conditions, but it is roughly within a certain range. With high vapor pressure, at room temperature, some molecules escape from the liquid surface to cause a certain concentration in the gas phase, which is easy to volatilize.
    In terms of solubility, it shows good miscibility in most organic solvents such as toluene of aromatics and dichloromethane of halogenated hydrocarbons, etc. Because the molecular structure is similar to that of organic solvents. However, the solubility in water is not good, because of its molecular polarity and low matching degree of water molecules, and the influence of hydrophobic groups, it is easy to layer when mixed with water.
    The density is slightly higher than that of common organic solvents. It is placed on the upper layer of a lighter density solvent and mixed with a high density solvent. There is a layering phenomenon according to the density difference. In addition, because of the large number of fluorine atoms in the molecule and the large electronegativity of fluorine atoms, the intermolecular force is unique, which affects the physical properties such as melting point and boiling point of substances, resulting in differences in the physical properties of compounds with similar structures.
    What are the synthesis methods of 2, 3, 4, 5, 6 - Pentafluorobenzenesulfonyl Chloride
    2% 2C3% 2C4% 2C5% 2C6 - Pentafluorobenzenesulfonyl Chloride is 2,3,4,5,6 - pentafluorobenzene sulfonyl chloride. The common synthesis methods are as follows:
    First, pentafluorobenzene is used as the starting material. Pentafluorobenzene is co-heated with fuming sulfuric acid and chlorosulfonic acid, which can provide sulfonic acid groups and chlorine atoms. Fuming sulfuric acid contains excess sulfur trioxide, which can enhance the sulfonation ability, and chlorosulfonic acid has the effect of both sulfonation and chlorination. At an appropriate temperature and reaction time, the sulfonic acid group replaces the hydrogen on the benzene ring, and then binds with the chlorine atom to form 2,3,4,5,6 - pentafluorobenzene sulfonyl chloride. The reaction process needs to be controlled by temperature. If it is too high, the side reactions will increase, and if it
    Second, pentafluorobenzoic acid is used as the starting material. First, pentafluorobenzoic acid is reacted with thionyl chloride, and the chlorine atom of thionyl chloride replaces the hydroxyl group of the carboxyl group to form pentafluorobenzoyl chloride. Subsequently, pentafluorobenzoyl chloride reacts with sulfuryl chloride under the action of a specific catalyst, and the sulfuryl chloride provides a sulfonyl group to obtain the final product. This route has a little more steps, but the reaction conditions are relatively mild and the purity of the product is easier to control.
    Third, pentafluorobenzene is used as the raw material. Pentafluorobromobenzene is first made into Grignard reagent with metal magnesium, and then reacts with sulfur dioxide to introduce a sulfonic acid group. Finally, it reacts with chlorinated reagents (such as phosphorus trichloride, thionyl chloride, etc.) to convert the sulfonic acid group into sulfonyl chloride, thereby synthesizing 2,3,4,5,6-pentafluorobenzene sulfonyl chloride. The preparation of Grignard reagent in this path requires an anhydrous and oxygen-free environment, and the reaction conditions are relatively high, but the atomic utilization rate is acceptable, and the raw material pentafluorobromobenzene is relatively easy to obtain.
    2, 3, 4, 5, 6 - Precautions for storage and transportation of Pentafluorobenzenesulfonyl Chloride
    2% 2C3% 2C4% 2C5% 2C6-pentafluorobenzenesulfonyl chloride requires many precautions when storing and transporting. This is a dangerous chemical substance, which is highly corrosive and toxic, and must be strictly followed by safety procedures.
    When storing, it is best to find a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent them from evaporating or triggering chemical reactions due to rising temperatures. It must be stored separately from alkalis, alcohols, water and other substances, because the substance is prone to violent reactions in contact with water or alkalis, and may also react dangerously with alcohols. The storage container must be tightly sealed to prevent leakage. And the container should be checked regularly for signs of damage or leakage, and if there is any, it must be dealt with in time.
    During transportation, it is necessary to choose suitable transportation tools. The container must be firm and sealed to prevent damage and leakage due to bumps and collisions during transportation. Transportation personnel should be professionally trained and familiar with the hazard characteristics of the chemical and emergency treatment methods. Transportation vehicles should be equipped with corresponding emergency treatment equipment and protective equipment, such as fire extinguishers, leakage emergency treatment tools, protective gloves, protective clothing, etc. During transportation, avoid exposure to the sun, rain, and do not mix with other contraindicated items.
    If a leak occurs accidentally, do not panic. Personnel should be evacuated to a safe area quickly, and irrelevant personnel should be strictly prohibited from approaching. Emergency personnel need to wear professional protective equipment, such as gas masks, chemical protective clothing, etc., before entering the leakage site. In the event of a small amount of leakage, it can be absorbed by inert materials such as sand and dry lime, and collected in a closed container for subsequent proper disposal. In the event of a large amount of leakage, a dike or pit should be built for containment, and a pump should be transferred to a special collector for recycling or transportation to a waste treatment site for disposal.
    In conclusion, the storage and transportation of 2% 2C3% 2C4% 2C5% 2C6-pentafluorobenzenesulfonyl chloride must be based on safety as the top priority, and various safety regulations and operating procedures must be strictly implemented, so as to effectively avoid accidents and protect the safety of personnel and the environment from harm.
    2, 3, 4, 5, 6 - What is the market price of Pentafluorobenzenesulfonyl Chloride?
    I think what you are asking is about the market price of 2,3,4,5,6-pentafluorobenzenesulfonyl chloride. However, the market price of this compound often changes due to various factors, and it is difficult to have a definite number to deal with it.
    First, the price of raw materials has a deep impact on it. If the price of the raw materials for preparing this compound is high, the price of the finished product will also rise; if the supply of raw materials is abundant, the price may decline. Second, the trend of supply and demand is also the key. If the market demand for this substance is strong and the supply is limited, the price will rise; conversely, if the supply exceeds the demand, the price will fall. Third, the technique of preparation also affects its price. If the new technology can increase productivity and reduce costs, it is expected to make the price close to the people.
    Furthermore, differences in regions and manufacturers can cause differences in prices. In prosperous places, due to the convenience of transportation and storage, the price may be stable; in remote places, the cost increases, and the price may be high. Different manufacturers, due to differences in scale, management, and technology, have poor pricing.
    Therefore, in order to know the exact price of 2,3,4,5,6-pentafluorobenzenesulfonyl chloride, it is necessary to constantly observe market dynamics, consult suppliers, and carefully examine the reasons for each impact, in order to obtain a more accurate number.