As a leading 2-(2,2-Difluoroethoxy)-N-(5,8-Dimethoxy[1,2,4]Triazolo[1,5-C]Pyrimidin-2-Yl)-6-(Trifluoromethyl)Benzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 2- (2,2-difluoroethoxy) -N- (5,8-dimethoxy [1,2,4] triazolo [1,5-c] pyrimidin-2-yl) -6- (trifluoromethyl) benzenesulfonamide
The chemical structure of 2-% (2,2-diethoxy) -N- (5,8-diacetyl [1,2,4] triazino [1,5-c] quinazoline-2-yl) -6- (triethoxy) phenothiazine is an interesting topic in the field of organic chemistry. This structure is an exquisite combination of many key parts, which is like a delicate chemical building.
Bear the brunt, the 2- (2,2-diethoxy) part, like the cornerstone of the building, endows the whole molecule with a specific spatial configuration and chemical activity. The presence of diethoxy groups not only affects the polarity of the molecule, but also determines its solubility and reactivity to a certain extent.
The N- (5,8-diacetyl [1,2,4] triazino [1,5-c] quinazoline-2-yl) fragment is like the main structure of a building, which is complex and critical. Among them, the fused ring structure of triazinoquinazoline endows the molecule with a unique electron cloud distribution and conjugation system, which in turn affects its spectral properties and stability. The modification of diacetyl groups further fine-tunes the electronic structure and steric resistance of the molecule, which has a profound impact on its biological activity or material properties.
The last 6- (triethoxy) phenothiazine part is like the decorative spire of a building. As an important heterocyclic compound, thiophenazine has good electron transport properties and photophysical properties. The introduction of triethoxy groups can optimize their solubility or change their intermolecular interactions, making the whole molecule show unique application potential in optoelectronic devices, drug research and development and other fields.
The various parts of this chemical structure cooperate with each other to jointly determine the overall properties and functions of the molecule. In the fields of organic synthetic chemistry and materials science, it is like a treasure containing endless mysteries, waiting for researchers to dig deeper.
What are the physical properties of 2- (2,2-difluoroethoxy) -N- (5,8-dimethoxy [1,2,4] triazolo [1,5-c] pyrimidin-2-yl) -6- (trifluoromethyl) benzenesulfonamide
2-% (2,2-diethoxy) -N- (5,8-diethoxy [1,2,4] triazino [1,5-c] pyrimidine-2-yl) -6- (triethoxy) quinoxaline, this compound has the following physical properties:
Its appearance is often in solid form, with strong intermolecular forces and relatively regular molecular arrangements, forming a stable lattice structure. In terms of solubility, the compound has a certain solubility in common organic solvents such as ethanol and acetone. Because some of its structures have similar polarities or intermolecular forces to organic solvents, it can be dissolved through the interaction of van der Waals forces, hydrogen bonds, etc. with solvent molecules; but it has poor solubility in water. Because the overall hydrophobic groups of the molecule account for a large proportion, it is difficult to form effective interactions with water molecules.
Melting point is an important physical property parameter for the compound, and its melting point is in a specific temperature range, which depends on factors such as intermolecular forces and lattice energy. Chemical bonds between molecules and the spatial arrangement of substituents will affect the melting point. For example, the stronger the intermolecular hydrogen bonds and van der Waals forces, the greater the lattice energy and the higher the melting point. The boiling point is also affected by the intermolecular force and the relative molecular mass. The relative molecular mass is large and the intermolecular force is strong. The energy required for gasification is more, and the boiling point is correspondingly higher.
Density is also one of the characteristics of this compound. Its density value reflects the mass of the substance per unit volume, which is related to the packing tightness of the molecules and the relative molecular mass. In the solid state, the tightness of the molecules determines the density. If the intermolecular arrangement is compact and the number of molecules per unit volume is large, the density is relatively large.
In addition, the compound may have a certain refractive index. The refractive index is related to the structure of the molecule and the distribution of the electron cloud, which can reflect the refractive characteristics of light propagation in the substance, providing an important reference for the identification and analysis of the compound. These physical properties are crucial for understanding their behavior in chemical reactions, separation and purification, and practical applications.
What is the synthesis method of 2- (2,2-difluoroethoxy) -N- (5,8-dimethoxy [1,2,4] triazolo [1,5-c] pyrimidin-2-yl) -6- (trifluoromethyl) benzenesulfonamide
To prepare 2- (2,2-diethoxyethyl) -N- (5,8-diethoxy [1,2,4] triazolo [1,5-c] pyrimidine-2-yl) -6- (triethoxy) quinazoline, the following ancient method can be carried out.
First take the appropriate raw material, take [1,2,4] triazolo [1,5-c] pyrimidine as the base, and introduce the ethoxy group at its 5,8 position. This step requires mild reaction conditions to ensure the selectivity of the reaction. Halogenated ethane and corresponding pyrimidine derivatives can be used in a basic environment with appropriate catalysts to make the ethoxy group connect smoothly.
Then, the two positions are modified to incorporate a group containing 2,2-diethoxyethyl group. This reaction can be carried out by means of nucleophilic substitution. The nucleophilic reagent containing diethoxyethyl group reacts with the pyrimidine derivative, during which the reaction temperature, time and reagent dosage need to be adjusted to obtain a high-purity product.
Furthermore, triethoxy is introduced into the quinazoline part. First, the skeleton of quinazoline can be constructed by cyclization of the corresponding aniline derivative and formamide and other reagents. Then, triethoxy is introduced at the 6th position. In this step, an electrophilic substitution reaction can be used to connect the triethoxy group to the 6-position quinazoline with a triethoxylation reagent under the action of a suitable Lewis acid catalyst.
After each step of the reaction, ancient purification methods such as recrystallization, column chromatography, etc. are required to remove impurities to obtain a pure product. Each step of the reaction requires fine operation and close monitoring to make this synthesis path proceed smoothly, and finally the product of 2- (2,2-diethoxyethyl) -N- (5,8-diethoxy [1,2,4] triazolo [1,5-c] pyrimidine-2-yl) -6- (triethoxy) quinazoline can be obtained.
2- (2,2-difluoroethoxy) -N- (5,8-dimethoxy [1,2,4] triazolo [1,5-c] pyrimidin-2-yl) -6- (trifluoromethyl) benzenesulfonamide is used in which fields
2-%282%2C2-%E4%BA%8C%E6%B0%9F%E4%B9%99%E6%B0%A7%E5%9F%BA%29-N-%285%2C8-%E4%BA%8C%E7%94%B2%E6%B0%A7%E5%9F%BA%5B1%2C2%2C4%5D%E4%B8%89%E5%94%91%E5%B9%B6%5B1%2C5-c%5D%E5%98%A7%E5%95%B6-2-%E5%9F%BA%29-6-%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E7%A3%BA%E9%85%B0%E8%83%BA, this substance is a complex organic compound. It has applications in many fields, as detailed below:
In the field of medicinal chemistry, such organic compounds containing specific substituents may exhibit unique biological activities. For example, some of these groups may interact with specific receptors in vivo, thereby affecting related physiological processes, or can be used as potential drug lead compounds, which can be further optimized and screened for activity, or are expected to be developed as drugs for the treatment of specific diseases.
In the field of materials science, due to its unique molecular structure, it may endow materials with special properties. For example, the introduction of such structural units in polymeric materials may improve the thermal stability, mechanical properties and optical properties of materials. It may be used to prepare high-performance engineering plastics, optical films and other materials to meet the special needs of different fields for material properties.
In the field of organic synthetic chemistry, the synthesis method and strategy of this compound also have important research value. By exploring efficient and green synthesis routes to achieve large-scale preparation, it not only helps to promote the development of organic synthesis methodologies, but also lays the foundation for its wide application in other fields. At the same time, in-depth study of its reaction mechanism can further expand the theoretical system of organic chemistry and provide theoretical guidance for the synthesis of more complex organic compounds.
2- (2,2-difluoroethoxy) -N- (5,8-dimethoxy [1,2,4] triazolo [1,5-c] pyrimidin-2-yl) -6- (trifluoromethyl) benzenesulfonamide market prospects
I heard that the rise and fall of the city is related to the wide range of needs and uses of things. Today there are 2 - (2,2 - diethoxy) - N - (5,8 - diethoxy [1,2,4] triazino [1,5 - c] quinazole - 2 - yl) - 6 - (triethoxy) naphthalene and pyrrolidone. If you want to understand the situation of its city, you should consider it multi-faceted.
Looking at its category, it may have its use in the fields of medicine and chemical industry. If it is in medicine, it may have specific pharmacological activity due to its unique chemical conformation, and can be used to create new agents and treat various diseases. In today's world, there is a huge need for medicine. If this product can meet the clinical shortage and solve the suffering of patients, it will be favored by pharmaceutical companies, and the city will also prosper. Just like the release of artemisinin in the past, it has saved countless malaria patients, and the city is widely distributed, which is known to the world.
In the chemical industry, or the key raw material for synthesizing other products, if the reaction path it participates in is simple and the yield is good, it can contribute to the chemical production chain. The chemical industry has a large scale and the demand for raw materials is constant. If it has this advantage, it will sell well.
However, it is also necessary to consider its difficulties. The process of synthesis may encounter complicated steps and high costs. If the cost is difficult to control, the competition in the market will be at a disadvantage. And the strict regulations, there are many rules for the entry of new compounds, which must be in compliance before they can enter the market for circulation.
Furthermore, the supply and demand of the city often changes with the advancement of science and technology and the change of ideas. If new technologies are released, there are better alternatives, and the city of this thing may be impacted.
To sum up, the market situation of 2- (2,2-diethoxy) -N- (5,8-diethoxy [1,2,4] triazino [1,5-c] quinazole-2-yl) -6- (triethoxy) naphthalene pyrrolidone has potential, opportunities, but also challenges. Only by using technology to reduce costs, acting in accordance with regulations, and observing changes in the city can we obtain a seat in the city, prosper its business, and benefit the world.