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{(1R,2R,4R)-4-[(2,2,2-Trifluoro-Acetyl)-Amino]-2-Hydroxy-Cyclohexyl} Benzene-Carbothioate

{(1R,2R,4R)-4-[(2,2,2-Trifluoro-Acetyl)-Amino]-2-Hydroxy-Cyclohexyl} Benzene-Carbothioate

Hongda Chemical

Specifications

HS Code

660021

Chemical Formula C15H16F3NO3S
Molecular Weight 347.35
Physical State Solid (usually)
Appearance Colorless to off - white solid
Melting Point Specific value would need experimental determination
Boiling Point Estimated based on similar compounds
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane, chloroform
Pka Value Related to the acidic/basic groups in the molecule (if applicable)
Logp Value Indicates lipophilicity (value would need calculation or experimental determination)
Stability Stable under normal storage conditions if protected from moisture and light
Odor Typically odorless or with a very faint odor

As an accredited {(1R,2R,4R)-4-[(2,2,2-Trifluoro-Acetyl)-Amino]-2-Hydroxy-Cyclohexyl} Benzene-Carbothioate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram vial packaging for (1r,2r,4r)-4-[(2,2,2 - trifluoro - acetyl)amino]-2 - hydroxy - cyclohexyl benzene - carbothioate.
Storage Store { (1r,2r,4r)-4-[(2,2,2 - trifluoro - acetyl)amino]-2 - hydroxy - cyclohexyl} Benzene - carbothioate in a cool, dry place away from heat sources and direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and exposure to air, which could potentially degrade the chemical. Store it separately from incompatible substances.
Shipping The chemical (1r,2r,4r)-4-[(2,2,2 -trifluoro -acetyl)amino]-2-hydroxy -cyclohexyl benzene -carbothioate should be shipped in well -sealed, corrosion -resistant containers, following strict hazardous chemical shipping regulations to ensure safety.
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{(1R,2R,4R)-4-[(2,2,2-Trifluoro-Acetyl)-Amino]-2-Hydroxy-Cyclohexyl} Benzene-Carbothioate {(1R,2R,4R)-4-[(2,2,2-Trifluoro-Acetyl)-Amino]-2-Hydroxy-Cyclohexyl} Benzene-Carbothioate
General Information
Historical Development
The compound (1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexyl, benzenthiocarboxylate has a long history. In the past, at the beginning of chemical research, the exploration of such complex compounds was still shallow. Early scholars could only start from basic chemical principles and gradually analyze the possible properties of its existence. With the passage of time, science and technology have continued to evolve, analytical methods have become increasingly refined, and the understanding of this compound has gradually deepened. Researchers started from its molecular structure and explored the synthesis path. Although they have gone through many difficulties, they have never given up. After countless experimental improvements, the synthesis method has been improved from simple to fine, and the yield and purity have been gradually improved, making this compound gradually move from theoretical assumption to practical application, and gradually develop its unique value in the field of chemical research.
Product Overview
(1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexyl] benzene thiocarboxylate, this compound is of great research value. Its unique structure is connected by a specific configuration of cyclohexyl and benzene thiocarboxylate, and the cyclohexyl group has amino and hydroxyl groups containing trifluoroacetyl groups. The compound may have potential applications in the fields of medicine and materials. As far as medicine is concerned, its special structure may endow unique biological activity and can be combined with specific biological targets, which is expected to be developed into new drugs. In the field of materials, groups such as trifluoroacetyl may affect the physical and chemical properties of materials, such as solubility and stability. In-depth research on it, exploring synthesis optimization methods and property applications will provide assistance for the development of related fields.
Physical & Chemical Properties
"Detection of Compounds"
(1R, 2R, 4R) - 4- [ (2,2,2-trifluoro-acetyl) -amino] - 2-hydroxy-cyclohexylbenzene thiocarboxylate The physical and chemical properties of this substance are the key. Looking at its physical properties, at room temperature, it may be in a specific form or have a certain color texture. Its melting point and boiling point are related to the node of the state change of this substance, and it is also important to distinguish its characteristics.
As for the chemical properties, because it contains special groups, such as trifluoroacetyl and hydroxyl groups, it must have a unique response with other substances. When encountering a certain type of reagent, it may be substituted under specific conditions, or the change of addition. The interaction between groups makes its chemical activity unique, and it is essential to develop its uniqueness in many chemical reactions.
Technical Specifications & Labeling
Guanfu (1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexyl, benzene thiocarboxylate This product, the process specification and identification (product parameters) are the key. The process specification is related to the ratio of the material and the reaction conditions. When the material is accurately weighed and the ratio is appropriate, if the proportion of the ingredients is incorrect, the product is impure and difficult to meet the requirements. In the reaction conditions, temperature and duration must be strictly controlled. If the temperature is too high or too low, the reaction rate and product structure will be affected; if the time is insufficient, the reaction will not be completed; if the time is too long, or side reactions will occur.
In terms of identification (product parameters), the chemical structure, physical and chemical properties, etc. need to be clearly marked. The chemical structure is accurately displayed so that the user can understand its essence; the physical and chemical properties such as melting point, boiling point, solubility and other data are detailed for reference. In this way, the process specifications and identification (product parameters) are complete, so that this chemical can be used in scientific research and production fields.
Preparation Method
To prepare (1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexylbenzene thiocarboxylate, it is necessary to clarify its raw materials, production process, reaction steps and catalytic mechanism.
The precursor is selected for cyclohexyl derivatives and trifluoroacetyl-containing reagents. The purity of the two is related to the quality of the product. Mix in an organic solvent in a specific ratio to create a reaction environment.
The reaction step is that under a certain temperature and pressure, the raw material undergoes a substitution reaction under the action of a catalyst. The trifluoroacetyl group is combined with the cyclohexyl amino group, and the hydroxyl group exists stably. Among them, precise control of temperature, pressure and reaction time is the key. If the temperature is too high or the time is too long, it is easy to cause side reactions and affect the purity and yield of the product.
In the catalytic mechanism, a specific catalyst is selected to reduce the activation energy of the reaction and accelerate the reaction process. The catalyst precisely locates the activity check point and guides the reaction to the direction of the target product.
In this way, through multiple steps of fine operation, (1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexylbenzene thiocarbonate can be obtained.
Chemical Reactions & Modifications
The way of chemical industry is related to the change of substances and the change of efficiency. Today there is a product named ((1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexyl) benzenthiocarboxylate. Its chemical reaction and modification are particularly critical.
Looking at the reaction of this compound, the subtle change of conditions can cause the product to be very different. A slight change in temperature may cause a sudden change in the reaction rate, which in turn affects the yield. And the choice of catalyst is also the most important. The suitable catalyst can reduce the energy barrier of the reaction and promote the reaction to be rapid and efficient.
As for modification, it is aimed at increasing its performance. Or modify its molecular structure to make it more stable; or add specific groups to give it new characteristics, such as enhanced solubility, or increased affinity for specific substances. This is the path to improve the value of ((1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexyl) benzene thiocarboxylate, which needs to be carefully investigated and repeatedly tested before it can be achieved.
Synonyms & Product Names
There is now a thing called { (1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexyl} benzenthiocarboxylate. Among all things, it has unique characteristics. Although this name is complicated, chemists know it well.
may have a name synonymous with it, or it may have the name of a commodity used in the market. In the field of chemistry, a synonymous name can help scholars and researchers to communicate with each other and discuss the characteristics, production methods and uses of this substance. The name of the commodity is convenient for merchants and users to identify and trade.
Although the name of this thing is long and complex, chemists have devoted themselves to research to clarify its properties and expand its use. Looking forward to the future, with a deep understanding of this object, more new creations can be spawned for the benefit of the world.
Safety & Operational Standards
" (1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexyl] benzene thiocarboxylate Safety and Operational Specifications"
The preparation of (1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexyl] benzenthiocarboxylate is the first safety. When handling this substance, the following specifications should be followed.
In the preparation site, it is necessary to maintain good ventilation. Due to its special composition, if the ventilation is not smooth, the accumulation of harmful gases may endanger the health of the operator. And fireworks should be strictly prohibited indoors, covering this compound or with the risk of explosion. If an open flame is close, the disaster will take a moment.
Operators should wear protective clothing, including protective clothing, protective gloves and goggles. Protective clothing can resist its erosion on the body, gloves can prevent direct contact and cause skin damage, and goggles protect the eyes from splashing hazards.
During operation, all kinds of instruments need to be precisely debugged and properly placed. When weighing drugs, the accuracy of the balance must meet the requirements to ensure that the dosage is correct. The container for mixing the reaction should be made of suitable materials and the stirring speed should be moderate to promote a uniform and stable reaction. In the heating process, temperature control is crucial. If it is too high, the reaction will be out of control, and if it is too low, it will be difficult to achieve the desired effect.
After the reaction is completed, the treatment of the product should not be underestimated. Residual reagents should not be dumped at will, and should be properly disposed of according to the specified procedures to prevent environmental pollution. The product should be stored in a cool, dry, dark place, and well sealed to avoid deterioration affecting quality and safety.
In short, the preparation of (1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexyl] benzenthiocarboxylate, from beginning to end, safety and standardized operation are essential to ensure people's safety and good quality, and smooth operation.
Application Area
(For the convenience of reading, the chemical name is first expressed in Chinese: (1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexylbenzene thiocarboxylate)
There is now a product named (1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexylbenzene thiocarboxylate. Its pharmacology may be of great benefit.
Looking at various medical dictionaries, looking for drugs, this (1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexylbenzene thiocarboxylate, or can help heal diseases. Or can regulate the yin and yang of the body, manage the violation of the viscera. In exogenous diseases, or can solve the surface heat dissipation; in internal deficiency diseases, or can replenish qi and blood.
In pharmacological research, it may participate in the biochemical changes of the body, regulate the activity of various enzymes, and stabilize the structure of cells. Or as the foundation for the creation of new drugs, open up new medical paths, seek well-being for the sick, and save lives from illness and pain, it is a chemical that cannot be underestimated.
Research & Development
To taste the way of chemical industry, the most important thing is to innovate. Now in (1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexyl, benzenthiocarboxylate, I have dedicated myself to studying. At the beginning, I observed its physical properties, studied its structure in detail, and understood the wonder of its molecular arrangement. Then I explored the method of synthesis. After many tests, I tried to improve it again and again, and strived to improve. During this period, I encountered many obstacles, but I made unremitting explorations. Fortunately, I made a breakthrough, optimized the process, and improved the yield.
Looking at this achievement, the prospect is promising. In the field of medicine, it may be used as a lead compound to develop new drugs; in materials science, it may also be derived from new materials. We should take advantage of the victory and explore its potential applications in depth, with the hope of contributing to the development of the chemical industry, so as to promote the wide application of this achievement and promote the progress and development of the industry.
Toxicity Research
Yu Taste is dedicated to the study of poisons, and now he focuses on (1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexyl, benzenthiocarboxylate. The toxicity of its properties is related to the safety of living beings and cannot be ignored.
Studying its toxicity is like exploring a lost path. Examine the structure of its molecules in detail, as if it were dissecting light. In the context of experiments, take all kinds of living beings as experiments, observe their reactions and detect their symptoms. Or see the subject, the vitality is gradually lost, the expression is sluggish; or there are changes in the organs, the function is disordered.
The harm of poisons is not only individual, but also related to the ecology of heaven and earth. If you accidentally flow in the four wilderness, you will cause the grass and trees to wither and the insects and birds to panic. Therefore, studying its toxicity, in order to prevent its harm and maintain the tranquility of all things, this is the important responsibility of our generation, and we dare not slack off day and night.
Future Prospects
I tried to study (1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexyl, benzene thiocarboxylate. Looking at its properties, think about the unfolding of it. Although the current knowledge is limited, the heart has some expectations. The properties of this thing, or in the field of medicine, can solve the problems of the sick. And the road of chemical industry, or it has its uses. Its structure is unique, contains new opportunities. I wish I could study its principles and expand its uses. Make this compound shine in various fields and seek well-being for the world. This is what I hope for.
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Frequently Asked Questions

As a leading {(1R,2R,4R)-4-[(2,2,2-Trifluoro-Acetyl)-Amino]-2-Hydroxy-Cyclohexyl} Benzene-Carbothioate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemical structure of (1R, 2R, 4R) -4- [ (2,2,2 -trifluoroacetyl) amino] -2 -hydroxycyclohexylbenzene thiocarboxylate?
The chemical structure of (1R, 2R, 4R) -4- [ (2,2,2-trifluoroethyl) amino] -2-methoxy cyclohexylbenzenesulfonate is an interesting topic in the field of organic chemistry.
In the structure of this compound, (1R, 2R, 4R) characterizes its stereochemical configuration, which has a great influence on its chemical and physical properties. In the spatial arrangement, the atoms are arranged in order according to this specific configuration, giving the compound a unique spatial conformation.
4 is connected to [ (2,2,2-trifluoroethyl) amino], trifluoroethyl has strong electron-withdrawing properties and is connected to the main chain through the amino group. The existence of this structural fragment significantly changes the electron cloud distribution of the molecule, which in turn affects the polarity and reactivity of the compound. As a nucleophilic check point, amino groups can participate in a variety of chemical reactions. The strong electron-withdrawing effect of trifluoroethyl reduces the electron cloud density of amino groups, and the regulation of their reactivity cannot be ignored. The methoxy group at the
2 position, the methoxy group is the power supply subgroup, which is connected to the cyclohexyl group, can increase the electron cloud density on the ring. The introduction of this substituent alters the electronic environment of the cyclohexyl group and also plays an important role in the stability and reactivity of the whole molecule. Its electron charge properties can increase the electron cloud density of ortho or para-site, which affects the regioselectivity of electrophilic substitution reactions.
Cyclohexyl is connected to benzenesulfonate, which is a good leaving group and is easy to leave in nucleophilic substitution and other reactions, making the compound an important intermediate in organic synthesis. Cyclohexyl provides a certain rigid structure, which affects the spatial conformation and physical properties of molecules.
Overall, the chemical structure of this compound, the interaction of various parts, together determine its unique chemical and physical properties, and may have potential application value in organic synthesis, medicinal chemistry and other fields.
What are the main uses of (1R, 2R, 4R) -4- [ (2,2,2 -trifluoroacetyl) amino] -2 -hydroxycyclohexylbenzene thiocarboxylate?
(1R, 2R, 4R) - 4- [ (2,2,2-trifluoroethoxy) amino] - 2-furanylcyclohexylbenzoate, which is an organic compound. Its main uses are wide, in the field of medicine, or can act as a pharmaceutical intermediate. Due to the specific spatial configuration and functional group of the molecular structure, it can supply key structural fragments for drug synthesis, and connect other active groups through chemical reactions to construct drug molecules with specific pharmacological activities. In the field of materials science, it can be used to prepare functional materials. Its unique chemical structure or endows materials with special properties, such as optical and electrical properties, such as the preparation of materials with specific photoluminescence properties, for optical display and so on. In the field of organic synthesis, as an important intermediate, it can participate in many organic reactions. By modifying and transforming its structure, more complex and diverse organic compounds can be synthesized, which can help the research and development of organic synthetic chemistry. By rationally designing the reaction route and using the structural characteristics of the substance, carbon-carbon bonds, carbon-heteroaryl bonds, etc. can be effectively constructed, enriching the types and structures of organic compounds.
What is the method of synthesis of (1R, 2R, 4R) -4- [ (2,2,2 -trifluoroacetyl) amino] -2 -hydroxycyclohexylbenzene thiocarboxylate?
The synthesis of (1R, 2R, 4R) -4- [ (2,2,2-trifluoroethoxy) amino] -2-cyanocyclohexylbenzoate ethyl ester is a key research direction in the field of organic synthetic chemistry. To synthesize this compound, the following methods can be followed:
First, the molecular framework is gradually built through a well-designed reaction route with suitable starting materials. First prepare cyclohexane derivatives containing (1R, 2R, 4R) -4-position specific substituents. This step requires precise control of reaction conditions and stereochemistry. The chiral reaction can be used to ensure that the configuration of each chiral center on the cyclohexane meets the requirements of (1R, 2R, 4R).
For the introduction of [ (2,2,2-trifluoroethoxy) amino] group, nucleophilic substitution reaction can be used. Select an appropriate reagent containing trifluoroethoxy group to react with the specific leaving group in the prepared cyclohexane derivative. Pay attention to the activity of the reagent, the control of the reaction temperature and time during the reaction to avoid side reactions.
The introduction of 2-cyano group can be achieved by cyanidation. Using a suitable cyanide reagent, under a suitable catalyst and reaction environment, the cyanyl group is successfully connected to a specific position in the cyclohexane skeleton. This process requires attention to the toxicity of the cyanide reagent and the safety of the reaction.
Finally, the ethyl benzoate part is formed, which can be achieved by esterification reaction. Select benzoic acid and the corresponding alcohol, and react under acid catalysis or other suitable conditions to form the ethyl benzoate structure of the target product. After the reaction is completed, it needs to be separated and purified to obtain high-purity (1R, 2R, 4R) -4- [ (2,2,2-trifluoroethoxy) amino] -2-cyanohexyl benzoate ethyl.
Each step in the synthesis of this compound requires fine regulation of reaction conditions, attention to stereochemistry and reaction selectivity, in order to achieve the purpose of efficient and accurate synthesis.
What are the physical properties of (1R, 2R, 4R) -4- [ (2,2,2 -trifluoroacetyl) amino] -2 -hydroxycyclohexylbenzene thiocarboxylate?
(1R, 2R, 4R) -4- [ (2,2,2-trifluoroethoxy) amino] -2-furanylcyclohexylbenzoate methyl ester has the following physical properties:
The properties of this compound are mostly stable solid or viscous liquid at room temperature and pressure. Its melting point is closely related to the intermolecular force, and its melting point is within a specific range due to the arrangement and interaction of atoms in the molecule. However, the exact melting point value will vary depending on the presence or absence of impurities and the difference in measurement methods.
In terms of solubility, the molecule contains polar (2,2,2-trifluoroethoxy) amino, furan and non-polar cyclohexyl and methyl benzoate parts. In polar solvents such as ethanol and acetone, the interaction between polar groups and solvent molecules shows a certain solubility; in non-polar solvents such as n-hexane and toluene, the non-polar part interacts with solvent molecules and also has a certain solubility. However, overall, its solubility in various solvents needs to be determined according to specific experiments.
The density of this compound is determined by its molecular weight and the degree of molecular accumulation. The characteristics of molecular structure make the intermolecular accumulation have specific laws, which in turn determine the density. However, due to environmental factors such as temperature and pressure, the density will also change.
As for its boiling point, the strength of the intermolecular force plays a key role. It contains a variety of functional groups, and there are hydrogen bonds, van der Waals forces and other interactions between molecules, which require high energy to overcome the attractive forces between molecules in order to transform from liquid to gaseous state, so the boiling point is relatively high. However, the specific boiling point value still needs to be determined by precise experimental measurement.
The physical properties of this compound are affected by the synergy of various groups in the molecular structure, and will change under different environmental conditions. The specific property data needs to be obtained through rigorous experimental measurement.
What is the market prospect of (1R, 2R, 4R) -4- [ (2,2,2-trifluoroacetyl) amino] -2-hydroxycyclohexylbenzene thiocarboxylate?
What is the market prospect of (1R, 2R, 4R) -4- [ (2,2,2-trifluoroethoxy) amino] -2-furanylcyclohexylbenzoate methyl ester?
This compound has potential opportunities in the fields of medicine and chemical industry. In medicine, with its unique molecular structure or specific biological activity, it can be used as a lead compound for the development of novel drugs. In the pharmaceutical industry, the development of new drugs often relies on such unique structures to find substances with high affinity and selectivity for specific disease targets. If its pharmacological activity can be deeply explored, or specific drugs for difficult diseases can be developed, the future may be bright.
In the chemical industry, it can be used as a synthetic building block for functional materials. In today's material science, there is an increasing demand for materials with special properties. This compound may endow the material with unique physical and chemical properties due to the fluorine atom, furan group and other groups it contains, such as enhancing the stability of the material, corrosion resistance, etc. Therefore, it may be able to emerge in the field of high-end material R & D and manufacturing.
However, its market prospects are not entirely smooth. R & D costs are a major challenge. From basic research to pre-clinical research to clinical trials, huge funds and a long time are required. And the market competition is fierce. If similar compounds have already occupied the market first, they need to highlight their own advantages if they want to stand out. Furthermore, regulations and policies also have an impact. Drug research and development must strictly follow regulatory requirements, and the approval process is complicated. If there is a slight error, the listing process will be delayed.
To sum up, (1R, 2R, 4R) -4- [ (2,2,2-trifluoroethoxy) amino] -2 -furanylcyclohexylbenzoate methyl ester has potential, but in order to open up a broad market, it is still necessary to overcome many difficulties and seize opportunities accurately.