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What are the main uses of (1H-Pyrrol-1-Yl) Pentafluorobenzene?
(1H-pyrrole-1-yl) pentafluorobenzene, which has a wide range of uses. In the field of organic synthesis, it is often a key intermediate. Due to its unique structure, the benzene ring is connected with pentafluoro substituents and pyrrole groups, giving it special chemical activities and properties.
In organic synthesis, by virtue of the activity check point of benzene ring and pyrrole group, complex organic molecules with diverse structures can be constructed through many chemical reactions, such as nucleophilic substitution, electrophilic substitution, etc. Chemists use this to synthesize organic materials with specific functions. In the field of optoelectronics, the synthesized organic materials may have excellent photoelectric properties and can be used as organic Light Emitting Diode (OLED) materials, which can contribute to the development of display technology. In the field of solar cells, the synthesized materials may effectively improve the photoelectric conversion efficiency of batteries.
In the field of medicinal chemistry, (1H-pyrrole-1-yl) pentafluorobenzene also has important value. Due to its special chemical structure, it may interact specifically with specific targets in organisms. Scientists can design and synthesize new drug molecules based on this, and modify their structures to optimize the activity, selectivity and pharmacokinetic properties of drugs. For example, synthetic drugs or the treatment of specific diseases have better curative effects and contribute to the cause of human health.
In addition, in the field of materials science, (1H-pyrrole-1-yl) pentafluorobenzene is involved in the synthesis of materials or has unique physical and chemical properties, such as high stability, low solubility, etc., which can be applied to the preparation of materials in special environments, providing a new way for the progress of materials science.
What are the physical properties of (1H-Pyrrol-1-Yl) Pentafluorobenzene?
The physical properties of (1H-pyrrole-1-yl) pentafluorobenzene are quite important and are described in detail below.
The state of this substance, at room temperature and pressure, or in a liquid state. Looking at its molecular structure, it is connected by a pyrrole group and pentafluorobenzene, and some atoms interact moderately, resulting in it being in the liquid state. Its color, or colorless and transparent, because there is no strong light-absorbing group in the molecular structure that can cause obvious color.
As for its taste, or with a special organic smell, the combination of pyrrole and pentafluorobenzene gives it a unique smell. However, due to individual sensory differences, the specific smell perception may be different.
Its boiling point is due to the intermolecular force, or within a certain range. The interaction between pyrrole ring and pentafluorobenzene makes the intermolecular attractive force non-weak, so the boiling point is not low, and moderate heat energy is required to cause it to boil into gaseous state.
In terms of melting point, because of its molecular regularity, the arrangement of molecules is relatively orderly, and the interatomic force, the melting point may also be at a certain value, so that the substance changes from solid to liquid at a specific temperature.
In terms of solubility, the substance may have a certain solubility in organic solvents. Because it is an organic compound, it can be soluble in organic solvents such as ether and chloroform according to the principle of similar phase solubility, but its solubility in water is not good, because its molecular polarity is quite different from water.
In terms of density, compared with common organic solvents, or different, the presence of fluorine atoms in the molecule increases its relative mass or changes its density, presenting a unique density value.
The physical properties of this (1H-pyrrole-1-yl) pentafluorobenzene are determined by its unique molecular structure, which is of key significance in chemical research and related application fields.
What are the synthesis methods of (1H-Pyrrol-1-Yl) Pentafluorobenzene
The synthesis method of (1H-pyrrole-1-yl) pentafluorobenzene has been known in ancient times, and now it is detailed for you.
First, it can be prepared by nucleophilic substitution reaction. React with pentafluorobenzene halide and pyrrole in the presence of suitable bases and solvents. Among them, potassium carbonate, sodium carbonate and other solvents such as N, N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO), etc., all have good solubility and stability, which can promote the smooth progress of the reaction. The reaction temperature usually needs to be carefully regulated, depending on the specific reactant activity, or in the range from room temperature to moderate heating, so that the halogen atom is replaced by pyrrole, resulting in (1H-pyrrole-1-yl) pentafluorobenzene.
Second, metal-catalyzed coupling reactions are also commonly used. For example, palladium-catalyzed coupling reactions can be used. Pentafluorophenylboronic acid or its derivatives and halogenated pyrrole are used as raw materials, and the reaction occurs in bases and specific solvents under the catalysis of palladium catalysts such as tetra (triphenylphosphine) palladium. Bases such as potassium phosphate, solvents such as toluene-ethanol mixed solvents, etc. The reaction conditions are relatively mild and the selectivity is quite good, and the carbon-carbon bond of the target product can be efficiently constructed to obtain (1H-pyrrole-1-yl) pentafluorobenzene.
Third, there is a method by modifying and converting compounds containing pyrrole and pentafluorobenzene structures. If a specific parent compound is selected, the compound needs to contain both pyrrole-related groups and pentafluorobenzene-related groups that are easy to modify, and it can be gradually converted into (1H-pyrrole-1-yl) pentafluorobenzene through suitable chemical reactions, such as oxidation, reduction, and substitution. However, this method requires high design and control of the reaction steps, and it is necessary to accurately grasp the reaction conditions of each step in order to achieve the expected synthesis effect.
What should be paid attention to when storing and transporting (1H-Pyrrol-1-Yl) Pentafluorobenzene?
For (1H-pyrrole-1-based) pentafluorobenzene, many matters must be paid attention to when storing and transporting. This substance has unique properties and is related to safety and quality, and should not be ignored.
When storing, the first priority environment. It should be placed in a cool, dry and well-ventilated place. The cover may be sensitive to temperature and humidity, and it is easy to deteriorate due to high temperature and humidity. If it is exposed to high temperature, or causes chemical reactions, it will damage its purity, or even cause dangerous accidents. Therefore, it is a priority to choose a suitable storage place.
Furthermore, it must be prevented from mixing with other things. ( 1H-pyrrole-1-yl) pentafluorobenzene may react with certain substances, such as strong oxidizing agents, strong acids and alkalis. Therefore, when storing, it should be strictly separated from such substances to ensure safety.
As for transportation, the packaging must be sturdy. Choose suitable packaging materials to resist vibration, collision and leakage. And during transportation, the escort should be familiar with its characteristics and emergency handling methods. In case of accident, it can be responded to in time to avoid major disasters.
In addition, the means of transportation must also be clean and free of impurities to prevent contamination of (1H-pyrrole-1-yl) pentafluorobenzene. Follow the established transportation procedures, follow the designated route, and do not change it at will to ensure the smooth transportation process. In this way, the substance must be properly stored and transported to avoid accidents and ensure its quality and safety.
What is the market price range for (1H-Pyrrol-1-Yl) Pentafluorobenzene?
I don't know what the market price range of (1H-pyrrole-1-based) pentafluorobenzene is. However, if you want to know the price of this product, you should follow various channels.
First, visit the chemical product trading platform. Now many such platforms gather many merchants, which list the prices of general chemical products. You can search for (1H-pyrrole-1-based) pentafluorobenzene in detail on it. According to the prices quoted by various companies, the prices are different due to different merchants or due to different sources, quality and quantity. A price range can be obtained from this.
Second, consult the chemical raw material suppliers. They have been involved in this industry for a long time and are familiar with the market. You can find well-known suppliers in the industry and ask about the price of (1H-pyrrole-1-based) pentafluorobenzene by phone, email, etc. Suppliers can quote a more accurate price according to their own costs, market supply and demand and other factors, and may have different quotations due to different purchase quantities.
Third, refer to industry reports. The chemical industry often produces various reports, which involve the market price analysis of (1H-pyrrole-1-based) pentafluorobenzene. According to market surveys, data analytics, etc., it can show the price trend of the product over a period of time and the current approximate price range, which is quite beneficial for grasping the market conditions.
Although I am unable to disclose the price range directly, following these steps, we should be able to obtain definitive information on the market price range of (1H-pyrrole-1-yl) pentafluorobenzene.