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1-Propoxy-2,3-Difluorobenzene

1-Propoxy-2,3-Difluorobenzene

Hongda Chemical

Specifications

HS Code

278722

Chemical Formula C9H9F2O
Molecular Weight 172.16
Appearance Colorless to light yellow liquid
Boiling Point Around 200 - 210 °C
Density Approx. 1.15 - 1.20 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
Flash Point Relatively high, details vary
Vapor Pressure Low at room temperature

As an accredited 1-Propoxy-2,3-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - propoxy - 2,3 - difluorobenzene in 500 - ml glass bottles, quantity: 10 bottles per carton.
Storage 1 - Propoxy - 2,3 - difluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent leakage and evaporation. Label the storage container clearly with the chemical name, hazards, and other relevant information for easy identification and safe handling.
Shipping 1 - propoxy - 2,3 - difluorobenzene is shipped in sealed, corrosion - resistant containers. Shipment adheres to strict chemical transport regulations, ensuring safety during transit to prevent leakage and environmental hazards.
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1-Propoxy-2,3-Difluorobenzene 1-Propoxy-2,3-Difluorobenzene
General Information
Historical Development
Fu 1 - Propoxy - 2,3 - Difluorobenzene is also an organic compound. Although its origin is difficult to study in detail, it has flourished since chemistry, and various sages have continued to study in the field of organic. In the past, chemists explored the properties and structure of substances, and gradually understood various methods of synthesis.
In the process of organic synthesis, this compound emerged. At first, the synthesis method was not good, and the yield was scarce, which was only a treasure in the laboratory. However, chemists are determined to improve the process and optimize the process. After generations of unremitting efforts, the synthesis method has become more and more mature, and the yield has also gradually increased. Therefore, 1-Propoxy-2,3-Difluorobenzene is gradually used in chemical, pharmaceutical and other industries, promoting the progress of various technologies and becoming an indispensable part of the history of chemical development.
Product Overview
1 - Propoxy-2,3 - Difluorobenzene is a chemical that I have been focusing on recently. This product has unique properties. It is a colorless and transparent liquid and has a slightly specific smell. It has a wide range of uses in the field of organic synthesis, and can be used as a key intermediate. It is of great value in drug development, materials science and other fields.
Preparation of this product requires many fine steps. First, a specific phenolic compound is taken, and it undergoes a nucleophilic substitution reaction with halogenated alkanes under suitable reaction conditions to obtain the first product. After purification, refining and other complex processes, high-purity 1 - Propoxy-2,3 - Difluorobenzene can be obtained.
Special attention should also be paid when storing and using. Due to its certain chemical activity, it should be avoided from contact with strong oxidants, strong acids, and other substances, and should be stored in a cool and ventilated warehouse to prevent deterioration or risk.
Physical & Chemical Properties
1 - Propoxy - 2,3 - Difluorobenzene is an organic compound. Its physical and chemical properties are quite critical. Looking at its physical properties, at room temperature, this substance may be in a liquid state, with a specific boiling point and melting point. The boiling point is related to the difficulty of its gasification, and the melting point is related to the temperature limit of its solidification.
Discuss the chemical properties. Because of its benzene ring structure, it has some commonality with aromatic hydrocarbons, and can undergo electrophilic substitution reactions. The presence of fluorine atoms and propoxy groups significantly affects its reactivity. Fluorine atoms have strong electronegativity, which reduces the electron cloud density of the benzene ring, and the electrophilic substitution reactivity is different from that of ordinary benzene derivatives. Propoxy groups are the power supply subgroups, which can change the selectivity of the reaction check point to a certain extent. The physicochemical properties of this compound are of great significance in the fields of organic synthesis and materials science, which affect its performance in various reactions and applications.
Technical Specifications & Labeling
1 - Propoxy - 2,3 - Difluorobenzene is a chemical I have been researching recently. Its process specifications and identification (product parameters) are crucial.
The process specifications need to be accurate. From the selection of raw materials, pure and suitable ones must be selected. To the reaction conditions, the temperature and pressure should be strictly controlled, and the quality should be completely different. The reaction time also needs to be properly controlled, so as to ensure the purity and yield of the product.
In terms of identification (product parameters), its chemical structure is clear, which is the foundation for identification. Physical properties such as melting point, boiling point, density and other data are the key to its qualitative. The identification of chemical properties is related to its stability and reactivity. And on the packaging, all parameters must be stated to inform the user to ensure the safety and accuracy of use. In this way, the essence of this chemical process specification and labeling can be obtained.
Preparation Method
Now I want to make 1 - Propoxy - 2,3 - Difluorobenzene, the method of making this product is the first raw material. When the appropriate starting material is taken, it is finely proportioned. The production process depends on the reaction step. First, the raw materials are mixed in a specific container, and the temperature and pressure are controlled to cause the reaction. When the reaction is carried out, it should be done in sequence without disorder.
The catalytic mechanism is also crucial. Choosing the appropriate catalyst can promote the reaction speed and yield. The amount and activity of the catalyst need to be precisely controlled. After various reaction steps, the product is gradually formed, and then purified and other steps, the impurity is removed and improved, and the final product is 1 - Propoxy - 2,3 - Difluorobenzene. This preparation method requires scientific regulations and caution in order to achieve optimum results.
Chemical Reactions & Modifications
Scholars of modern times study 1 - Propoxy - 2,3 - Difluorobenzene. Its transformation and change are important for learning. To understand its response, explore its qualitative change, in order to enter this industry.
Observe its response, seek the best method to make it abundant and pure. Examine the conditions of response, such as temperature, pressure, catalyst, etc. Observe the effect of the catalyst, the rise and fall of temperature, how to change the speed and yield of response.
Change its structure, or obtain heterogeneity. After various trials, seek beneficial changes and increase the use of this product. Such as changing its chain, adjusting its foundation, and observing its change.
Scholars should be diligent, taking the past as a mirror, combining the wisdom of the past with the wisdom of the present, adapting and changing in transformation, exploring in depth, hoping to obtain new fruits, and promoting the progress of this product.
Synonyms & Product Names
1 - Propoxy - 2,3 - Difluorobenzene, the synonym and trade name of this thing, are related to the scope of my chemical research. Its synonyms may vary according to the habits of different regions and research groups. Although its chemical nature is unique, it has different names, just like all things in the world. Although the names are different, they actually refer to the same.
As for the trade name, it is the name taken by the merchant to promote this product, aiming to show its uniqueness in the market and attract the attention of buyers. Or according to its characteristics, uses, or auspicious meaning, in order to facilitate sales. If we study such chemicals, we need to check all kinds of literature, manufacturer information, distinguish synonyms and trade names, in order to use them accurately and without confusion, which is of great significance to chemical research and production practice. In this way, we can explore the secrets of chemistry without hindrance.
Safety & Operational Standards
1 - Propoxy - 2,3 - Difluorobenzene is an important chemical product. It needs to be explained in detail in terms of its safety and operating practices.
When preparing this product, all raw materials must be accurately weighed to ensure that the dosage meets the regulations. The utensils used should also be clean and dry to prevent impurities from mixing and affecting the purity of the product. During the reaction process, temperature control is crucial. The temperature needs to be precisely adjusted according to the specific reaction requirements to ensure a smooth reaction. If the temperature is too high, the reaction may be runaway and dangerous; if the temperature is too low, the reaction will be slow and affect the production efficiency.
Store this chemical in a cool, dry and well-ventilated place. Keep away from fire and heat sources and avoid direct sunlight. Due to its certain chemical activity, improper storage is prone to deterioration and even cause safety accidents. Storage containers must be well sealed to prevent leakage.
During operation, operators must wear appropriate protective equipment, such as protective clothing, gloves and goggles, to prevent chemicals from coming into contact with the skin and eyes. In case of inadvertent contact, rinse with plenty of water immediately and seek medical attention in time.
Waste disposal should not be ignored. Waste containing 1-Propoxy-2,3-Difluorobenzene should be properly disposed of in accordance with relevant environmental regulations and should not be discarded at will to avoid pollution to the environment.
Only by strictly following safety and operating practices can the production, storage, use and disposal of 1-Propoxy-2,3-Difluorobenzene be ensured to be safe, while ensuring product quality and maintaining a clean environment.
Application Area
1 - Propoxy - 2,3 - Difluorobenzene, its application field is very critical. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize specific drugs, or has unique curative effects on specific diseases, adding powerful tools for doctors to treat diseases. In the field of material science, its characteristics may optimize material properties, such as enhancing material stability, improving durability, and making utensils more durable. In the fragrance industry, or because of its unique chemical structure, it gives spices a unique flavor and produces unique fragrances to meet the world's needs for fragrance and diversity. All these applications highlight the important value of 1 - Propoxy - 2,3 - Difluorobenzene in various fields and provide assistance for the development of many industries.
Research & Development
I am committed to the research and development of 1 - Propoxy - 2,3 - Difluorobenzene. This material has unique characteristics and has potential in various fields. At first, analyze its structure, explore its physicochemical properties, and clarify its reaction rules. Then study its synthesis method, try various paths, and seek efficient and pure methods. Although the process is difficult, it is tirelessly researched. After many tests, the process has been improved, so that the yield has gradually increased and the quality is also excellent. Looking at its prospects, it can be used in medicine, materials and other industries, and is expected to promote the progress of related fields. I will continue to explore, hoping to better understand its nature, expand its use, and contribute to its development, so as to help this substance develop its capabilities in the world and benefit everyone.
Toxicity Research
I have studied a lot of chemistry. Recently, I focused on the compound 1-Propoxy-2,3-Difluorobenzene to investigate its toxicity in detail.
After many experiments, its effects on organisms were observed. In the experiment of mice, an appropriate amount of injection of this compound showed that the mice moved gradually, their diet was reduced, and they were convulsing from time to time. Detailed analysis of its causes, including the characteristics of fluorine, oxygen and other atoms in its chemical structure, interacted with biochemical reactions in mice.
Looking at its effect on aquatic organisms, if a small amount of this substance was thrown into water, the vitality of aquatic plankton was greatly reduced, and reproduction was also hindered.
From this point of view, the toxicity of 1-Propoxy-2,3-Difluorobenzene cannot be underestimated, and it is potentially harmful to both the environment and organisms. Follow-up research should investigate its mechanism of action and find proper protection and treatment methods to avoid its harm and maintain ecological safety and biological health.
Future Prospects
I have studied 1 - Propoxy - 2,3 - Difluorobenzene, and I deeply feel that it has a broad vision for future development. Today's technology is new, and the chemical industry is also advancing rapidly. 1 - Propoxy - 2,3 - Difluorobenzene has potential in various industries.
Looking at the pharmaceutical industry, it may be a key raw material for the creation of new drugs, helping medical scientists to develop and treat difficult diseases, and for the health and well-being of the world. In material science, it may be possible to improve the properties of materials to make them more suitable for high-end technology products.
Although there may be thorns ahead, I firmly believe that with time, its endless potential will be tapped. All scientific researchers should work together to explore and study it, and use it as a foundation to open up a new field of future chemical industry, so that 1-Propoxy-2,3-Difluorobenzene can shine and create brilliance in the unfinished path.
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Frequently Asked Questions

As a leading 1-Propoxy-2,3-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Propoxy-2,3-Difluorobenzene?
1-Propoxy-2,3-difluorobenzene is also an organic compound. Its main use is quite extensive and has applications in various fields.
First, in the field of pharmaceutical chemistry, it is often a key intermediate for the synthesis of drugs. Due to its unique chemical structure, it can be introduced into the molecular structure of drugs through a series of reactions to improve the physicochemical properties of drugs, such as solubility and stability, and it also affects the interaction between drugs and targets, helping to create new drugs with specific curative effects.
Second, it also has important uses in materials science. It can be used as a raw material for the synthesis of materials with special properties. For example, it can be used to prepare organic materials with specific optical and electrical properties. With its fluorine-containing and alkoxy-based structural characteristics, the prepared materials may exhibit excellent properties in photoluminescence, electroluminescence, etc., and may have potential applications in organic Light Emitting Diode (OLED) and other fields.
Third, in the field of fine chemicals, it also plays an important role. It can be a starting material for the synthesis of fine chemicals, and through various chemical reactions, a variety of high-value-added products can be derived, such as special fragrances, additives, etc. Its unique structure endows the refined chemicals with specific aroma, stability and other characteristics, meeting the needs of different industrial and consumer markets. In conclusion, 1-propoxy-2,3-difluorobenzene, with its unique chemical structure, is an indispensable compound in the fields of medicine, materials, and fine chemicals, which is of great significance for promoting the development of related industries.
What are the physical properties of 1-Propoxy-2,3-Difluorobenzene?
1 - Propoxy - 2,3 - Difluorobenzene is an organic compound, and its physical properties are particularly important for its application in various fields.
First word appearance, this compound is often colorless to light yellow transparent liquid, with a clear appearance and no significant impurities. Its color and transparency are crucial in many industrial and scientific applications, and its quality and performance are affected due to the strange appearance or the presence of implied impurities.
As for the boiling point, the boiling point of 1 - Propoxy - 2,3 - Difluorobenzene is within a specific range. The value of the boiling point is closely related to the intermolecular forces. There are Van der Waals forces between the molecules of this compound, which cause it to change from liquid to gaseous at a specific temperature. The exact boiling point data is of great significance for distillation, separation and other operations, which can help the experimenter or producer to accurately control the conditions and achieve effective separation and purification.
Melting point is also one of the key physical properties. The melting point of a compound reflects its lattice energy and the tightness of molecular arrangement. The melting point of 1 - Propoxy - 2,3 - Difluorobenzene or in a specific low temperature range, the solid state time particles are arranged in an orderly manner, and when heated to the melting point, the lattice structure disintegrates and turns into a liquid state.
In terms of density, 1 - Propoxy - 2,3 - Difluorobenzene has a certain density value. Density plays a significant role in the mixed system, which can be used to determine its floating or sinking in the solution, and also helps to calculate the mass under a specific volume, which is indispensable in the quantitative analysis and preparation process.
Solubility is also an important property. 1 - Propoxy - 2,3 - Difluorobenzene has good solubility in organic solvents, such as common ethanol, ether, etc. This property makes it a reaction medium in organic synthesis, and it is also conducive to the dissolution and reaction of solutes. The solubility in water may be poor due to its molecular structure having a certain hydrophobicity and weak interaction with water molecules.
In addition, the vapor pressure of 1 - Propoxy - 2,3 - Difluorobenzene also has its characteristics. Vapor pressure reflects the difficulty of volatilization at a certain temperature. When the vapor pressure is high, the compound is more volatile to the gas phase. This property should be paid attention to during storage and use to prevent volatilization loss or cause safety problems.
The above physical properties are interrelated and jointly determine the behavior and application of 1-Propoxy-2,3-Difluorobenzene. In practical operation and research, fully knowing and making good use of these properties can maximize the effectiveness of this compound.
Is 1-Propoxy-2,3-Difluorobenzene Chemically Stable?
The stability of the chemical properties of 1-propoxy-2,3-difluorobenzene is related to many factors.
In this compound, the benzene ring has a conjugated structure, which makes its chemical properties stable to a certain extent. The fluorine atom on the benzene ring has a strong electronegativity, which affects the electron cloud distribution of the benzene ring. The electron-absorbing induction effect of the fluorine atom can reduce the electron cloud density of the benzene ring, making it difficult for the electrophilic substitution reaction to occur, but also enhancing the stability of the nucleophilic reagent.
The propoxy group is attached to the benzene ring, and its carbon-oxygen single bond. The bond energy of carbon-oxygen single bond is considerable, and the lone pair electrons of the oxygen atom can form a conjugation effect with the benzene ring, which can enhance the molecular stability to a certain extent. However, the long carbon chain of the propoxy group, or the steric hindrance effect, affects the molecular reactivity and stability.
Under normal conditions, 1-propoxy-2,3-difluorobenzene can remain relatively stable without extreme reaction conditions such as strong oxidants, strong acids, and strong bases. However, in the presence of high temperature, high pressure, or specific catalysts, the substituents or reactions on the benzene ring, such as nucleophilic substitution, oxidation, etc., affect its stability.
In general, 1-propoxy-2,3-difluorobenzene has certain chemical stability in conventional environments, but under certain severe conditions, its stability or destruction occurs chemically.
What are the synthesis methods of 1-Propoxy-2,3-Difluorobenzene?
The synthesis method of 1-propoxy-2,3-difluorobenzene has been used throughout the ages. The common method is the selection of starting materials. First, you can start from 2,3-difluorophenol and react with halopropane, which is a classic nucleophilic substitution path. In this reaction, choose an appropriate base, such as potassium carbonate, in a suitable solvent, such as N, N-dimethylformamide (DMF), heat and stir, the halogen atom of halopropane is active, and the oxygen atom of phenol hydroxyl is quite nucleophilic. The two then undergo a substitution reaction to generate the target product 1-propoxy-2,3-difluorobenzene.
Furthermore, 2,3-difluorobenzene can also be used as the starting material to react with propanol in an alkaline environment and in the presence of a catalyst. At this time, the base can promote the oxygen atom of propanol to form alkoxide anions, enhancing its nucleophilicity, while the halogen atom of halobenzene is affected by the benzene ring and also has a certain activity. The two combine and undergo nucleophilic substitution to reach the target product.
In addition, the reaction involving organometallic reagents is also a good method for synthesis. For example, under the action of palladium catalyst, 2,3-difluorophenylboronic acid and halogenated propoxy compound follow the Suzuki coupling reaction mechanism, and the two are coupled to form 1-propoxy-2,3-difluorobenzene. This method has relatively mild conditions and good selectivity, which can effectively avoid the occurrence of many side reactions.
The synthesis method has advantages and disadvantages due to factors such as the availability of raw materials, the ease of control of reaction conditions, and the high and low yield. It needs to be carefully selected according to the actual situation to achieve the purpose of synthesis.
What is the price range of 1-Propoxy-2,3-Difluorobenzene in the market?
I have not heard the exact price of 1 - Propoxy - 2,3 - Difluorobenzene in the market. This compound is not an unusually easy to obtain, and its price often varies according to a variety of reasons.
First, the source of the material. If the raw material is easy and rich, the price may be slightly flat; if the raw material is rare and rare, the price must be high.
Second, the preparation is difficult. If the synthesis of this compound requires exquisite methods, harsh conditions, or many setbacks, the labor cost will be high, and the price will also rise.
Third, the situation of demand and supply. If the market demand is large but the supply is small, the price will rise; if the supply exceeds the demand, the price may drop.
Fourth, the difference in purity. High purity, because of its difficulty in preparation and refinement, the price must be higher than that of low purity.
The price of chemical materials in the market changes from time to time. To know the exact price of 1 - Propoxy - 2,3 - Difluorobenzene, you can consult the chemical material supplier or visit the relevant chemical trading platform to get the exact price range in the near future.