1-Phenoxy-4- (trifluoromethyl) benzene, which has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. The phenoxy group and trifluoromethyl group in the molecular structure give unique chemical activity and physical properties.
In organic synthesis, trifluoromethyl can effectively regulate the reactivity and selectivity due to its strong electron-absorbing properties. For example, in the construction of complex aromatic compounds, 1-phenoxy-4- (trifluoromethyl) benzene can participate in many nucleophilic and electrophilic substitution reactions, helping chemists to precisely construct the required molecular structure.
In the field of materials science, it has also emerged. Because it contains trifluoromethyl, it can significantly improve the chemical stability, thermal stability and weather resistance of the material. Therefore, it is often used in the preparation of high-performance polymer materials, such as special engineering plastics, functional coatings, etc. These materials are widely used in aerospace, electronics and other fields that require strict material properties.
In the field of pharmaceutical chemistry, its role should not be underestimated. The introduction of trifluoromethyl into drug molecules can often change the metabolic kinetic properties of drugs, enhance the ability of drugs to bind to targets, improve drug efficacy and reduce toxicity. 1-phenoxy-4 - (trifluoromethyl) benzene, as an intermediate, can participate in the synthesis of a variety of compounds with potential biological activities, providing key raw materials for the development of new drugs.
In summary, 1-phenoxy-4- (trifluoromethyl) benzene, with its unique structure, has important uses in organic synthesis, materials science, medicinal chemistry, and other fields, promoting technological progress and development in related fields.

1-Phenoxy-4- (trifluoromethyl) benzene is also an organic compound. It has unique physical properties and is very important in the chemical industry and other fields.
Looking at its properties, it is mostly colorless to light yellow liquid under normal conditions, which is the appearance of the eye. Although its smell is not strong and pungent, it also has a special aroma. If it is smelled in a poorly ventilated place for a long time, it may cause discomfort.
When it comes to the boiling point, it is about a certain temperature range, and this characteristic is related to its distillation and separation operations. The value of its boiling point makes it possible for the substance to change from liquid to gaseous state under specific temperature conditions. This is a key parameter in the distillation process of chemical production.
Melting point also has a specific value. When the temperature drops below the melting point, 1-phenoxy-4- (trifluoromethyl) benzene will condense from liquid to solid, and this process affects its storage and transportation.
Furthermore, solubility is also an important physical property. In organic solvents such as ethanol and ether, its solubility is quite good and it can be uniformly dispersed. However, in water, the solubility is very small. Due to the characteristics of its molecular structure, the force between water molecules is weak and it is difficult to blend.
In terms of density, it is relatively stable and slightly larger than that of common light organic solvents. This density characteristic affects its delamination and material transportation operations in mixed systems.
Its vapor pressure varies accordingly at different temperatures, which is related to its existence in the gas phase and the degree of volatilization, and has an impact on the safety of the working environment and product quality.
The above physical properties are interrelated. In many fields such as organic synthesis and material preparation, they are all elements that need to be carefully considered, and are of great significance to the design and optimization of related processes.

The chemical stability of 1-phenoxy-4- (trifluoromethyl) benzene is related to many aspects. The structure of this compound, the phenoxy group is connected to the benzene ring containing trifluoromethyl.
From the perspective of chemical bonds, in the phenoxy group, the oxygen atom is connected to the benzene ring, and the formed bond has a certain stability. The oxygen atom has a solitary pair of electrons, which can conjugate with the benzene ring, reducing the energy of the system, and this part of the structure is relatively stable. The benzene ring itself has a conjugated large π bond, which also gives a certain stability to the overall structure.
As for the trifluoromethyl group, the electronegativity of the fluorine atom is extremely high, and This group is connected to the benzene ring, which will reduce the electron cloud density of the benzene ring and affect the reactivity of the benzene ring. However, at the same time, due to the large bond energy of C-F, the structure of trifluoromethyl is relatively stable.
In common chemical environments, 1-phenoxy-4- (trifluoromethyl) benzene is relatively stable under normal temperature and pressure without specific reagents or conditions. However, in case of extreme conditions such as strong oxidants or high temperature, the benzene ring or phenoxy part may undergo oxidation and other reactions. Although trifluoromethyl is stable, under some harsh conditions, the C-F bond may also break. Overall, the chemical properties of this compound are still stable under general experimental and storage conditions, but under specific reaction systems and extreme conditions, its stability will be challenged and corresponding chemical changes will occur.

The common methods for synthesizing 1-phenoxy-4- (trifluoromethyl) benzene are as follows.
First, the halogenated benzene and phenol salt containing trifluoromethyl are used as raw materials. Take an appropriate amount of 4-halogenated-trifluoromethylbenzene, such as 4-chloro-trifluoromethylbenzene, and mix it with the phenol salt in a suitable reaction vessel. The phenol salt can be prepared by reacting the corresponding phenol with a base, such as sodium hydroxide or potassium carbonate, in a suitable solvent. The reaction is stirred at a certain temperature in an organic solvent, such as N, N-dimethylformamide (DMF) or dimethyl sulfoxide (DMSO). This kind of reaction requires a controlled temperature between 60 ° C and 120 ° C, and the reaction time is about 6-12 hours. During the reaction, the halogen atom of halogenated benzene undergoes a nucleophilic substitution reaction with the oxygen atom of phenol salt, resulting in 1-phenoxy-4- (trifluoromethyl) benzene.
Second, a coupling reaction catalyzed by transition metals. 4 - (trifluoromethyl) phenyl boric acid and halogenated phenyl ether are used as substrates. First, 4 - (trifluoromethyl) phenylboronic acid and halogenated phenyl ether, an appropriate amount of transition metal catalysts, such as palladium catalysts (such as tetra (triphenylphosphine) palladium), and bases (such as potassium carbonate, sodium carbonate, etc.) are added to organic solvents (such as toluene, dioxane, etc.). Under nitrogen protection atmosphere, heat to 80 ° C - 110 ° C, and the reaction lasts for 4-8 hours. Transition metal catalysts can promote the formation of carbon-oxygen bonds between phenylboronic acid and halogenated phenyl ether, and achieve the synthesis of 1-phenoxy-4 - (trifluoromethyl) benzene.
Third, 4- (trifluoromethyl) phenol can also be reacted with halogenated benzene under appropriate conditions. Mix 4- (trifluoromethyl) phenol with halogenated benzene, such as bromobenzene or chlorobenzene, and alkali (such as sodium hydride, potassium tert-butoxide, etc.) in an anhydrous organic solvent (such as tetrahydrofuran). At low temperature, the base first reacts with 4- (trifluoromethyl) phenol to form a phenate, and then the phenate undergoes a nucleophilic substitution reaction with halogenated benzene. The reaction temperature is about 0 ° C - 50 ° C, and the reaction time is about 3 - 6 hours. The final product is 1-phenoxy-4- (trifluorometh

I do not know the price range of 1 - Phenoxy - 4 - (Trifluoromethyl) Benzene in the market. This is a special chemical, and its price often changes due to many factors such as purity, source, market supply and demand. If you want to know its price, you can consult the chemical supplier, or find its quotation on the chemical trading platform or professional chemical product website. However, the quotation of such platforms may vary from time to time, and the prices quoted by different suppliers are also different. You may also communicate with relevant chemical industry personnel to obtain relatively accurate price range information. However, it is difficult for me to determine the price range of it in the market based on the available information.