1-Nitro-4-Trifluoromethoxy-Benzene

Hongda Chemical

Specifications

HS Code	870988
Chemical Formula	C7H4F3NO3
Molar Mass	193.106 g/mol
Appearance	Solid or liquid (depending on conditions)
Physical State At Room Temperature	Solid (usually)
Boiling Point	Data may vary, typically high due to molecular structure
Melting Point	Data specific to the compound needed
Density	Value depends on conditions, needs experimental determination
Solubility In Water	Low solubility (organic nature)
Solubility In Organic Solvents	Good solubility in common organic solvents
Odor	May have a characteristic organic odor
Stability	Stable under normal conditions but reactive under certain chemical environments
Flash Point	Value specific to the compound required for flammability assessment

As an accredited 1-Nitro-4-Trifluoromethoxy-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	500g of 1 - nitro - 4 - trifluoromethoxy - benzene packaged in a sealed plastic bottle.
Storage	1 - nitro - 4 - trifluoromethoxy - benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container to prevent vapor leakage. It is advisable to store it in a dedicated chemical storage cabinet, separated from incompatible substances to ensure safety.
Shipping	1 - nitro - 4 - trifluoromethoxy - benzene, a chemical, is shipped in specialized, well - sealed containers to prevent leakage. It follows strict regulations for hazardous chemicals during transport, ensuring safety during transit.

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General Information

Historical Development

1 - Nitro - 4 - Trifluoromethoxy - Benzene, the thing that transforms it. Its initial research began with the understanding of the original. In the early days, it was limited to the lack of refinement of the technique, and the method of inspection was poor. For this thing, the fur was involved.
Then the moon is changed, and the technique is difficult. The craftsman is diligent in research, and the method of cultivation is more and more exquisite. From the renewal of the instrument to the completion of the understanding, the research of this thing is recommended. What was done in the past is now easy to do.
The power of the generation, 1 - Nitro - 4 - Trifluoromethoxy - Benzene's nature, the method of the human. In the field of engineering, its use is also increasing day by day. From the initial ignorance and exploration to the present day, it has been widely used. This is the brilliant process of research and development, and it is also the unremitting spirit of those who work hard.

Product Overview

1 - Nitro - 4 - Trifluoromethoxy - Benzene is an important compound involved in the process of chemical research. It has unique properties, with nitro and trifluoromethoxy groups on the benzene ring. The introduction of nitro groups endows this substance with specific reactivity, and the existence of trifluoromethoxy groups also significantly affects its physical and chemical properties.
This substance is not easy to prepare, and requires fine temperature control, appropriate reagents, and a specific reaction path to obtain it. From the perspective of its structure, the stable structure of the benzene ring interacts with the functional groups at both ends to create a unique chemical environment. In the field of organic synthesis, it can be used as a key intermediate for the creation of many complex compounds.
It has a wide range of uses. In the field of pharmaceutical research and development, it may be able to assist in the design of new drug molecules; in the field of materials science, it may be able to contribute to the synthesis of materials with special properties. We chemical researchers should continue to study this substance, tap its potential, and do our best for chemical development and human well-being.

Physical & Chemical Properties

1 - Nitro - 4 - Trifluoromethoxy - Benzene is also an organic compound. Its physical and chemical properties are related to scientific research and are quite important.
Looking at its physical properties, under room temperature, or as a solid state, it has a specific color and state. Its melting point and boiling point are intrinsic values. The measurement of the melting point can observe the change of the physical state; the study of the boiling point can know the temperature of gasification.
On its chemistry, the structure of nitro and trifluoromethoxy gives it unique activity. Nitro is oxidizing and can participate in many processes in chemical reactions. The existence of trifluoromethoxy affects the polarity of the molecule, so that the compound exhibits different chemical behaviors under specific environments. This compound is a key intermediate in the field of organic synthesis, which helps to create new substances and is of great significance to the progress of chemical research.

Technical Specifications & Labeling

1 - Nitro - 4 - Trifluoromethoxy - Benzene is an important chemical raw material, and its preparation process is crucial. The first raw material selected in the process specification needs to select high-purity reactants to ensure product quality. The reaction conditions also need to be precisely controlled, the temperature should be maintained in a specific range, and the pressure must also meet the specified value.
As for the product label, the words "1 - Nitro - 4 - Trifluoromethoxy - Benzene" should be clearly marked on the prominent part of the package, indicating the key product parameters, such as purity, molecular weight, etc. And a warning label should be attached to indicate its chemical properties and latent risk to ensure the safety of users. Adhering to this process specification and labeling guidelines ensures that the product is of high quality and safe to use.

Preparation Method

To make 1 - Nitro - 4 - Trifluoromethoxy - Benzene, the raw materials and production process are very critical. The selection of raw materials should be accurate to ensure the purity of the product. In the production process, the reaction steps need to be rigorous.
First take an appropriate amount of halogenated aromatics containing fluorine, and mix them with nitric acid and sulfuric acid in a mixed acid co-reactor. Temperature control in a suitable range is the key, because temperature affects the reaction rate and product ratio. During the reaction, closely observe its changes, and adjust the temperature and speed in a timely manner.
After the reaction is completed, neutralization, extraction and other post-treatment processes are used to remove impurities. Then, by means of distillation, pure 1 - Nitro - 4 - Trifluoromethoxy - Benzene is obtained. In this process, the catalytic mechanism cannot be ignored, and the high-efficiency catalyst is selected to promote the reaction and yield. And during the operation, strictly abide by the procedures to ensure safety and control quality to obtain high-quality products.

Chemical Reactions & Modifications

In modern times, chemical refinement has deepened in the study of various compounds. 1 - Nitro - 4 - Trifluoromethoxy - Benzene, its chemical reaction and modification are worth studying.
Looking at the reaction, under specific temperature, pressure and catalyst conditions, it can combine with several reagents. Or break its old bonds to generate new structures. If it encounters nucleophiles, the fluoromethoxy group is often the place for the reaction. The nucleophile attacks it, causing the rearrangement of bonds and the formation of new bonds.
As for modification, its nitro group or fluoromethoxy group can be modified to change its physical and chemical properties. Or adjust its polarity to make it different in solubility in different solvents; or change its reactivity to make it more suitable for specific reactions. This is all a way for chemical researchers to seek innovation and change, hoping to clarify its properties and make good use of it, and contribute to various fields.

Synonyms & Product Names

1 - Nitro - 4 - Trifluoromethoxy - Benzene, the synonym and trade name of this substance, is related to the details of chemical research. Its synonyms are also known as 4 - (trifluoromethoxy) nitrobenzene in the industry. The two refer to the same chemical substance. The trade names are different in the market circulation and trading, or depending on the manufacturer and use. However, their essence is a compound of this specific chemical structure. Although the names of chemical substances are different, their core characteristics and compositions remain unchanged. When researchers explore and use this object, they need to clarify the various names to avoid confusion, so as to accurately carry out experiments, research and development, and in the field of chemistry, in-depth exploration of the mysteries of its properties, reactions, and applications.

Safety & Operational Standards

1 - Nitro - 4 - Trifluoromethoxy - Benzene is a chemical substance. It is crucial to its safety and operating practices and should not be ignored.
When preparing this compound, all steps must follow a precise process. In the initial stage, the raw materials used must be carefully verified, and their purity and quality must be up to standard before they can be used in the reaction. If the reagent is used, no impurities must be mixed in to avoid affecting the quality of the product.
During the reaction process, temperature control is extremely critical. It must be monitored with precise instruments to make the reaction proceed within a suitable temperature range. If the temperature is too high, it may cause overreaction or cause danger; if the temperature is too low, the reaction will be slow and affect the output of the product. For example, the optimum reaction temperature is set to a specific value, and the fluctuation range should not exceed a little to ensure a smooth reaction.
Furthermore, the atmosphere of the reaction environment cannot be ignored. Or it needs to be operated under the protection of inert gas to prevent adverse reactions between raw materials or products and oxygen, water vapor, etc. in the air.
After the product is made, its storage is also regulated. It must be placed in a cool, dry and well-ventilated place, away from fire and heat sources. The storage container must also be adapted to ensure a tight seal and prevent leakage.
When handling this compound, the operator's protection is essential. Professional protective equipment, such as protective clothing, gloves, goggles, etc., must be worn to avoid harm to the human body.
And the experimental site must be equipped with emergency equipment and measures. Such as fire extinguishing devices, eye washers, etc., in case of emergencies.
In short, the safety and operation specifications of 1 - Nitro - 4 - Trifluoromethoxy - Benzene cover all aspects of preparation, storage, operation, etc. Only with caution at all times can the experiment be smooth and the personnel and environment are safe.

Application Area

1 - Nitro - 4 - Trifluoromethoxy - Benzene is also a chemical material. Its application field involves a wide range of things. In the field of medicine, it can be the basis for creating special and good medicines. With the characteristics of this material, it can help the structure of the medicine to be exquisite, increase its efficacy, and cure various diseases.
In the field of agrochemical, it also has its uses. It can be used as a raw material for synthesizing strong pesticides to protect crops, drive away pests, and maintain the hope of a bumper harvest. And in material science, it can participate in the synthesis of special materials. Make the material have unique properties, such as corrosion resistance and heat resistance, to meet many special needs. From this point of view, 1 - Nitro - 4 - Trifluoromethoxy - Benzene has important value in various application fields and is indispensable for chemical research and industrial development.

Research & Development

I am dedicated to the research of 1 - Nitro - 4 - Trifluoromethoxy - Benzene. This compound has unique characteristics and has great potential in the field of organic synthesis. At the beginning, I explored its structure and properties, and after complex experiments, I gained some understanding.
In order to promote its development, we have studied various synthetic pathways. Try a variety of raw materials and reaction conditions, or high temperatures, or add special catalysts. Despite many obstacles, such as low yield and frequent side reactions, we did not give up easily.
After repeated exploration, we finally found a better method to improve yield and purity. This achievement has also attracted attention in the industry. In the future, its application scope should be further expanded, such as in the fields of medicine and materials, to explore new paths for the development of this compound, so that it can demonstrate value in more aspects and contribute to scientific research and industry.

Toxicity Research

In today's world, it is very important to investigate the toxicity of chemical substances. Today, 1-Nitro-4-Trifluoromethoxy-Benzene this compound.
The toxicity of this substance is related to the safety of living beings and the state of the environment. Examine its properties carefully, and we must use a cautious method. Looking at the structure of its molecule, nitro and trifluoromethoxy are combined with benzene ring, which may cause it to have unique chemical activity.
After various experiments, observe its impact on living things. In micro-organisms, or disturb their metabolic process; in higher organisms, it may also damage their visceral organs. And if this substance is scattered in the environment, or difficult to eliminate for a long time, it will cause water, soil and air to be dyed by it.
is based on the current plan, when the toxicity of 1-Nitro-4-Trifluoromethoxy-Benzene is studied, its harm is understood, and the solution is found, in order to protect the spirit of all things and protect the peace of the universe.

Future Prospects

Fu 1 - Nitro - 4 - Trifluoromethoxy - Benzene, a new product of chemistry. It is unique and has untapped potential in various fields.
Looking at today's world, science and technology are changing day by day, this product may be used to improve medicine to help heal various diseases and benefit the common people. Or in the field of materials, it can develop its superpower to make tough and specific materials for equipment and construction, making them increasingly sophisticated.
Furthermore, in chemical production, it may be used as a key agent to optimize processes and increase productivity. Although it is not widely used at the moment, I am convinced that with time, it will be able to shine brightly and become an indispensable element in the future development, leading the chemical and related industries to a new frontier, which is a promising future.

Where to Buy 1-Nitro-4-Trifluoromethoxy-Benzene in China?

As a trusted 1-Nitro-4-Trifluoromethoxy-Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 1-Nitro-4-Trifluoromethoxy-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Nitro-4-Trifluoromethoxy-Benzene?

1 - Nitro - 4 - Trifluoromethoxy - Benzene, Chinese name 1 - nitro - 4 - trifluoromethoxy benzene, this substance has a wide range of uses and is involved in various fields of chemical industry.
First, it is often used as a key intermediate in the synthesis of medicine. In the process of many new drug development, based on this, a series of chemical reactions can build specific chemical structures and help synthesize compounds with unique pharmacological activities. For example, when developing specific drugs for specific disease targets, the chemical properties of 1-nitro-4-trifluoromethoxybenzene can make it ingeniously participate in the reaction, giving the final drug the ideal curative effect and pharmacokinetic properties.
Second, it also plays an important role in the field of pesticide creation. Due to its special chemical composition and structure, pesticides made from this starting material may have high insecticidal, bactericidal or herbicidal properties. With its structural advantages, it can accurately act on specific physiological processes of pests, pathogens or weeds, achieve good control effect, and have relatively little impact on the environment, which is in line with the current development trend of green pesticides.
Third, it is also applied in the field of materials science. In the preparation of some functional materials, the introduction of 1-nitro-4-trifluoromethoxybenzene structural units can significantly improve the properties of the materials. For example, in the modification of polymer materials, it can be integrated into the polymer chain, or the heat resistance and chemical corrosion resistance of the material can be improved, and the application range of the material in extreme environments can be expanded.
Fourth, in the field of organic synthesis chemistry, as an important aromatic compound, it provides the starting skeleton for the construction of many complex organic molecules. Chemists can derive a wide variety of organic compounds by selectively transforming their nitro, trifluoromethoxy and other functional groups, which greatly enriches the research content and methods of organic synthesis chemistry.

What are the physical properties of 1-Nitro-4-Trifluoromethoxy-Benzene?

1-Nitro-4-trifluoromethoxy benzene, this is one of the organic compounds. Its physical properties are unique and related to its application in the chemical industry and other fields.
Let's talk about the appearance first. 1-nitro-4-trifluoromethoxy benzene is usually in a colorless to light yellow liquid state. It has clear fluidity, just like smart water, but it is not pure water. This color and morphology are one of the important characteristics to distinguish this substance in industrial production or experimental operations.
Furthermore, the boiling point is a term, and the boiling point of this compound is quite high, about in a specific numerical range (the specific value depends on the accurate determination). A higher boiling point means that it can be converted into a gaseous state at a relatively high temperature. In actual production, the heating temperature needs to be controlled to reach the boiling point to achieve separation, purification and other operations, so as not to cause the decomposition of compounds or other side reactions due to improper temperature.
Melting point is also a key property. The melting point of 1-nitro-4-trifluoromethoxy benzene is within a certain range. When the temperature drops below the melting point, it solidifies from liquid to solid. The characteristics of the melting point are extremely important in storage and transportation. It is necessary to ensure that the ambient temperature is suitable so that it does not change the physical state due to temperature fluctuations and affect the quality.
In terms of solubility, 1-nitro-4-trifluoromethoxybenzene has its own characteristics in organic solvents. It is soluble in some organic solvents, such as common toluene, dichloromethane, etc., but difficult to dissolve in water. This difference in solubility plays a significant role in chemical synthesis, extraction and other operations. It can be used to achieve separation from other substances in different solvents due to its different solubility in different solvents, or to carry out chemical reactions in specific solvents.
Density is also one of its physical properties. Its density is higher than that of water. When experiments or production involve stratification and other operations, it can be clearly distinguished from the water layer according to the density difference, and then liquid separation and other operations can be carried out to achieve the purpose of separation.
In addition, the vapor pressure of 1-nitro-4-trifluoromethoxylbenzene has corresponding values at different temperatures. The vapor pressure affects the degree of volatilization, and the temperature increases, the vapor pressure increases, and the volatilization accelerates. This property is reflected in the ventilation requirements of storage and use environments, and it is necessary to prevent its volatilization and accumulation, which may cause safety hazards.
The above is the main physical properties of 1-nitro-4-trifluoromethoxylbenzene. Each property is interrelated and jointly determines its behavior and application in the chemical industry.

Is 1-Nitro-4-Trifluoromethoxy-Benzene chemically stable?

1-Nitro-4-trifluoromethoxy-Benzene, which is 1-nitro-4-trifluoromethoxy-benzene, is relatively stable in its properties. Its stability is derived from the characteristics of molecular structure.
Looking at its molecules, nitro (-NO 2O) and trifluoromethoxy (-OCF 🥰) are attached to the benzene ring. The benzene ring has a conjugated system, which endows the benzene ring with special stability, making it difficult to withstand the attack of general reagents.
Nitro has strong electron absorption, which can reduce the electron cloud density of the benzene ring, making it difficult for electrophilic substitution to occur. Due to its electron-absorbing and conjugation effects, the electron cloud on the benzene ring is more biased towards nitro, which makes it difficult for other electrophilic reagents to approach the carbon atoms on the benzene ring, thus enhancing molecular stability.
Trifluoromethoxy also has electron-absorbing properties. Although its electron-absorbing ability may be slightly inferior to that of nitro, it also has a significant impact on the electron cloud distribution of the benzene ring. The existence of trifluoromethyl (-CF 🥰), due to the large electronegativity of fluorine atoms, further reduces the electron cloud density of the benzene ring through the induction effect. At the same time, the oxygen atoms are connected to the benzene ring, and although there is a certain electron-giving conjugation effect, in general, the electron-absorbing induction effect of trifluoromethoxy groups is dominant, which also helps to improve
In addition, the C-F bond energy of 1-nitro-4-trifluoromethoxylbenzene is higher, the radius of fluorine atoms is small, and the covalent bond formed with carbon atoms is stable. The C-O bond in the trifluoromethoxy group is also quite stable. This stable chemical bond structure makes the whole molecule less prone to bond fracture, thereby enhancing its chemical stability.
In summary, the conjugated system of 1-nitro-4-trifluoromethoxylbenzene, the electron-absorbing effect of nitro and trifluoromethoxy, and the stable chemical bond structure exhibit good chemical stability.

What is the production process of 1-Nitro-4-Trifluoromethoxy-Benzene?

1-Nitro-4-trifluoromethoxy benzene, the method of preparation, according to the delicate chemical technology. The process is based on a specific starting material, through many clever reactions.
Initially, a suitable aromatic hydrocarbon is often selected, and this aromatic hydrocarbon needs to have a check point that can introduce nitro and trifluoromethoxy groups. First perform a nitrogenation reaction to introduce the nitro group into a specific position of the aromatic hydrocarbon. When nitrogenation, choose a suitable nitrogenation reagent, such as a mixed acid of nitric acid and sulfuric acid, and react at the appropriate temperature and time according to the exact ratio. This step requires careful temperature control to prevent side reactions from clumping and impurity of the product.
After the nitro group is successfully introduced, the step of trifluoromethoxylation is carried out. In this step, special reagents containing trifluoromethoxy are used, and with the help of catalysts, trifluoromethoxy can smoothly replace the corresponding hydrogen atoms on aromatic hydrocarbons. The choice of catalyst is crucial, which can promote the efficient and directional progress of the reaction. The reaction environment also needs to be carefully controlled, such as the nature of the solvent, the pH of the reaction system, etc., which are all related to the success or failure of the reaction and the quality of the product.
After each step of the reaction, it must go through the process of separation and purification. Or use distillation to separate the target product and impurities according to the difference in the boiling point of each substance; or use extraction to enrich the product by using the difference in solubility of the substance in different solvents. Or use recrystallization to purify the product from the solution to achieve high purity requirements.
In this way, through various rigorous operations and exquisite control of each link, excellent quality 1-nitro-4-trifluoromethoxy benzene can be prepared.

What is the price range of 1-Nitro-4-Trifluoromethoxy-Benzene in the market?

1 - Nitro - 4 - Trifluoromethoxy - Benzene, it is also a thing of transformation. If you want to know the quality of the city, it will not be cheap. The quality of this thing, because of the general reason.
First, the supply and demand of the city are greatly reduced. If you ask for it, but the supply is small, the price will rise; on the contrary, if the supply is in demand, it will not fall. Second, the ease of its creation also affects the price. If the method is diverse, the materials used are rare, and the workmanship is vast, and the cost is not cheap; if it is easy to make, the cost is low, and the price is also different.
Furthermore, different places have different prices. The difference between the price and the price can make a difference. In addition, the price of the market also affects its price. Commercial sales, or those who offer customers with a price, or set by them.
With common sense, the price of this product may range from 10 yuan per gram to 100 yuan per gram. However, this approximate deduction is not natural. If you want to know the exact price, you need to contact the business and sales of chemical raw materials, or check the price of the market under the chemical trading platform, in order to obtain the real price.