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1-Nitro-2,3,4,6-Tetrafluorobenzene

1-Nitro-2,3,4,6-Tetrafluorobenzene

Hongda Chemical

Specifications

HS Code

881703

Chemical Formula C6HF4NO2
Appearance Colorless to light yellow liquid
Boiling Point 154 - 156 °C
Density 1.605 g/cm³
Solubility Insoluble in water, soluble in organic solvents
Flash Point 59.4 °C
Refractive Index 1.457

As an accredited 1-Nitro-2,3,4,6-Tetrafluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - nitro - 2,3,4,6 - tetrafluorobenzene packaged in 500 - gram bottles.
Storage 1 - nitro - 2,3,4,6 - tetrafluorobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reducing agents, and reactive substances to prevent chemical reactions. Ensure proper labeling for easy identification.
Shipping 1 - nitro - 2,3,4,6 - tetrafluorobenzene is a chemical. Shipping requires proper containment in approved containers. It must comply with hazardous materials regulations, ensuring secure transport to prevent leakage and potential risks.
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1-Nitro-2,3,4,6-Tetrafluorobenzene 1-Nitro-2,3,4,6-Tetrafluorobenzene
General Information
Historical Development
1 - Nitro - 2, 3, 4, 6 - Tetrafluorobenzene is also a thing of transformation. At the beginning, the research is rare, and the knowledge is still shallow. However, as time goes by, the strength of all the wise people investigates, and gradually its nature becomes clear. At the beginning, the preparation method was complicated and difficult, and the yield was also small. Later scholars gradually enlightened their wisdom, and the method was also improved, and the yield increased. In the field of chemical industry, it is widely used, and it can be used as a raw material to make all kinds of fine products. In the past, the limitations of its cognition are now deeper and deeper. From the past to the present, from the end of the micro, the trend of development has arisen, like the flow of rivers, gushing endlessly. The progress of chemistry has been indispensable, and its prospects are also bright and impressive.
Product Overview
1 - Nitro - 2,3,4,6 - Tetrafluorobenzene is a unique chemical substance. It may be a colorless liquid with unique physical and chemical properties.
In this compound, the nitro group is cleverly connected to the tetrafluorobenzene ring, giving it special chemical activity. The presence of nitro groups makes it show a unique reaction tendency in many chemical reactions, or can participate in nucleophilic substitution and other reactions. The fluorine atom on the benzene ring, due to its high electronegativity, greatly affects the electron cloud distribution of the molecule, enhancing the stability and chemical inertness of the molecule.
In the field of synthesis, 1-Nitro-2,3,4,6-Tetrafluorobenzene can be used as a key intermediate to construct more complex organic molecular structures and open up new paths for organic synthetic chemistry. In the field of materials science, its unique structure may endow materials with special properties, such as improved heat resistance and chemical stability.
Physical & Chemical Properties
1 - Nitro - 2,3,4,6 - Tetrafluorobenzene, also an organic compound. Its physical and chemical properties are quite specific. Looking at its color, it is often colorless, such as the clarity of a clear spring. Smell it, it has a slightly pungent smell, but it is not a bad smell.
On its boiling point, it is about a specific value, which varies slightly according to the environment. Its melting point is also fixed, and at a specific temperature, it can be converted from solid to liquid. As for solubility, in some organic solvents, it can be well miscible, such as water, which is difficult to dissolve, and its molecular structure is quite different from the polarity of water.
Its chemical properties are active, and the presence of nitro and fluorine atoms makes it easy to participate in many chemical reactions. In the case of nucleophiles, the substitution reaction often occurs, and the fluorine atom can be replaced by other groups, and then new compounds can be derived. It has a wide range of uses in the field of organic synthesis.
Technical Specifications & Labeling
Today there is a thing, the name is 1 - Nitro - 2, 3, 4, 6 - Tetrafluorobenzene. The technique of its preparation is related to many delicacies.
In the process of preparation, the technician should know the ratio of materials, which is the first priority. The proportion of each thing is accurate, and the best product can be obtained. The temperature of the reaction also needs to be carefully observed. If it is too high, the quality will be variable, and if it is too low, it should be difficult to make. The control of the duration should not be ignored. If it is long, the quality will be damaged, and it will not be ripe for the time being.
The evaluation of its product, depending on its color, should be pure and correct, without variegated dye. Looking at its state, it should be in line with its inherent shape. To measure its performance, all parameters must meet the specified In this way, it is a qualified product and can be used in various applications.
Preparation Method
1 - Nitro - 2,3,4,6 - Tetrafluorobenzene is an important chemical substance, and its preparation method is related to many key elements.
In the selection of raw materials, compounds with specific structures such as fluorine and nitro groups should be used as reaction initiators. In terms of preparation process, the first reaction step is designed. First, the fluorine-containing compound is mixed with the nitrogenation reagent in a specific ratio, and the reaction is initiated at a specific temperature and pressure, so that the nitro group is precisely introduced into the molecular structure. This process requires strict regulation of the reaction conditions to ensure the smooth progress of the reaction.
Furthermore, the catalytic mechanism is also indispensable. A high-efficiency catalyst is selected to accelerate the reaction process and improve product selectivity. This catalyst should have high activity and stability, and play a key role in the reaction environment. The efficient preparation of 1-Nitro-2, 3, 4, 6-Tetrafluorobenzene is expected to be achieved through the synergistic combination of raw materials, preparation process, reaction steps and catalytic mechanism.
Chemical Reactions & Modifications
Today there is a thing called 1-Nitro-2,3,4, 6-Tetrafluorobenzene. In the field of chemistry, it is crucial to explore its reaction and modification.
Looking at its reaction, this compound often undergoes substitution when it encounters a specific reagent. The activity of its nitro and fluorine atoms leads to various chemical changes. However, the initial reaction has many shortcomings, the rate is slow and the yield is not ideal.
As for modification, after repeated research, the method of modifying the molecular structure can be used. Or add specific groups, or adjust the space arrangement to change its chemistry. After modification, the reaction rate gradually increases, and the yield also rises significantly. And the stability is better, and the application path is wider.
After unremitting research, the chemical reaction and modification of 1-Nitro-2,3,4, 6-Tetrafluorobenzene have gradually obtained exquisite methods, paving the way for its application in various fields.
Synonyms & Product Names
1 - Nitro - 2, 3, 4, 6 - Tetrafluorobenzene This thing, its synonymous name and the name of the product, are all subject to careful examination by our chemical researchers.
The names of the chemical substances are synonymous or different due to different academic contexts and regional habits. This 1 - Nitro - 2, 3, 4, 6 - Tetrafluorobenzene may have another name in the industry, and they all refer to the same thing. Its trade names also vary with merchants and markets.
When I explore this thing, I must carefully examine all the synonymous names and the names of the products to make it clear that they are related. Although the names are different, they are actually the same chemical entity. Therefore, in the end of experimentation, production, and trading, it can be accurate and not confused. If the name of the synonym and the name of the commodity cannot be distinguished in detail, it is afraid that in practical application, it will lead to many mistakes, which will be unfavorable to chemical research and industrial operation. Therefore, it is the priority of chemical researchers to study the synonym and the name of the commodity in detail.
Safety & Operational Standards
1 - Nitro - 2, 3, 4, 6 - Tetrafluorobenzene is also a chemical product. For its safe operation, it is necessary to deal with it.
Where this product is received, it must first be used to check the safety of the material. Its nature is special, or it is dangerous. Handle it well, and follow the standard.
As far as operation is concerned, it is clear and accessible to good places. If it is kept in a secret room, there is a risk of agglomeration. The utensils used must be stained to prevent the reaction of the accident and cause accidents.
When you take it, your hands must be stained, and the quantity must be stained. Do not be quick and negligent. Do not overflow. If it is accidentally damaged in the muscles or eyes, quickly wash it with a large amount of water, and ask for it immediately.
If you store it, it is appropriate to store it in the dry time, and the source of fire and heat. Store other things separately to prevent their interaction. The package must be in good condition. If there is any damage, you should immediately update it to prevent leakage.
If it is leaked, don't panic. First, the source of fire is prohibited from approaching. A small amount of leakage should be collected by adsorption of sand, vermiculite, etc. A large amount of leakage should be blocked, and then properly handled.
The safe operation of 1 - Nitro - 2, 3, 4, 6 - Tetrafluorobenzene is all in place. Follow the instructions and keep it safe.
Application Area
1 - Nitro - 2, 3, 4, 6 - Tetrafluorobenzene has a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to assist in the synthesis of pharmaceutical components, to develop new agents, and treat various diseases. In the field of material science, it is also very useful. It can make special functional materials and provide material advantages, such as enhancing its stability and weather resistance. In the field of electronic chemistry, it can be used as a raw material for the manufacture of electronic components to improve the performance of components and make them more precise and efficient. Therefore, 1 - Nitro - 2, 3, 4, 6 - Tetrafluorobenzene is indispensable in many fields and is of great significance to technological progress and industrial development.
Research & Development
In the field of chemical industry, new substances emerge one after another. 1 - Nitro - 2,3,4,6 - Tetrafluorobenzene is the object of my dedicated research.
In the course of experiments, I carefully observed its physical properties and explored its reaction rules. After many trials, I found that it changes when it encounters a certain agent, and under a certain temperature and pressure, its properties are different. The synthesis method has also been improved several times, and the yield is quite low at the beginning. After fine-tuning the ratio of materials and changing the timing of the reaction, the yield gradually increases.
Looking forward to its development, it can be used to create new materials, which have potential in the fields of electronics and medicine. Or it can add its characteristics to electronic components to make their performance better; in medicine, or it can become the basis for new agents to solve patients' diseases. I will do my best to promote the development of this product, and do my best for the prosperity of chemical industry.
Toxicity Research
In the chemical industry, there are many types, and poisons are hidden in it, which cannot be ignored. Today there is 1 - Nitro - 2, 3, 4, 6 - Tetrafluorobenzene, which is the key to toxicity research.
This substance is also strong in nature, or has the ability to erode the viscera. Looking at the structure of its molecules, nitro and fluorine atoms coexist, and the structure is unique. The source of toxicity may come from this. To verify it, if you put it into insects, many insects will kill; if you apply it to plants, plants will wither. Although it has not been widely tested on humans, its toxicity can be known.
And the volatilization of this thing, dispersed in the air, if inhaled, it may hurt the lungs, cause coughing, asthma, and damage the organs for a long time. Its flow in water, aquatic things are also difficult to escape, and the ecological balance may be broken.
Therefore, where it is prepared and used, protection measures are indispensable. Practitioners must wear special clothes and protective gear, and be careful to prevent the invasion of toxicity. This toxicity study is related to living things and must not be ignored.
Future Prospects
Although the current knowledge of 1 - Nitro - 2,3,4,6 - Tetrafluorobenzene is limited, its future prospects should not be underestimated. Our chemical researchers, studying the physical properties and mechanisms, hope to explore its hidden properties.
This compound has a unique structure, and the positions of fluorine and nitro give it different activities. Or in the preparation of new materials, it can be used as a key agent to make the material have specific properties, such as high stability and unique optical properties, paving the way for future material innovation.
Or in the field of drug development, with its special structure, it precisely fits the target and becomes a specific drug to solve the suffering of patients. Although the road ahead is long, we will uphold the heart of research and not be afraid of difficulties. We will surely be able to explore its vast application world, seek well-being for future generations, and explore the infinite possibilities of the future.
Where to Buy 1-Nitro-2,3,4,6-Tetrafluorobenzene in China?
As a trusted 1-Nitro-2,3,4,6-Tetrafluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Nitro-2,3,4,6-Tetrafluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Nitro-2,3,4, 6-Tetrafluorobenzene
1-Nitro-2,3,4,6-tetrafluorobenzene is also an organic compound. Its main uses are quite wide, and it plays an important role in chemical synthesis.
First, it can be a key raw material for pharmaceutical synthesis. The process of pharmaceutical preparation requires the construction of specific organic molecules. 1-nitro-2,3,4,6-tetrafluorobenzene has a unique chemical structure, containing nitro and fluorine atoms. It can be introduced into target molecules through many chemical reactions, such as nucleophilic substitution, reduction, etc., to shape the required active structure to help develop new drugs and treat various diseases.
Second, it is also very useful in the field of pesticide creation. Pesticides need to be highly active against specific pests, bacteria, etc. The structural properties of this compound can endow pesticides with excellent biological activity and environmental adaptability. By chemical modification, it can be converted into pesticide ingredients with insecticidal, bactericidal or weeding functions, improving crop yield and quality, and protecting the prosperity of agriculture.
Third, it also contributes to materials science. Because it contains fluorine atoms, it can enhance some properties of materials, such as corrosion resistance and heat resistance. After polymerization or other chemical means, it can be integrated into polymer materials to prepare special materials with excellent performance, which can be used in high-end fields such as aerospace and electronics to meet the needs of special environments.
All of these, 1-nitro-2,3,4,6-tetrafluorobenzene is an indispensable and important substance in many industries such as chemical, pharmaceutical, pesticide, and materials, promoting progress and development in various fields.
What are the physical properties of 1-Nitro-2,3,4, 6-Tetrafluorobenzene
1 - Nitro - 2, 3, 4, 6 - Tetrafluorobenzene is an organic compound with unique physical properties, which is now detailed by you.
Looking at its properties, at room temperature and pressure, it mostly shows a colorless to light yellow liquid state. This color state characteristic is quite critical in the identification of chemical raw materials and can be used as a basis for preliminary identification.
When it comes to density, it is heavier than water, about 1.7g/cm ³. This characteristic makes it have a specific behavior in processes involving operations such as stratification. When mixed with liquids with different densities such as water, it will be stratified according to density differences. This phenomenon has important applications in chemical processes such as separation and purification.
In terms of boiling point, it is roughly between 180-190 ° C. The boiling point is the temperature at which a substance changes from liquid to gaseous state, and this boiling point range determines the conditions during heat treatment. In the separation process of distillation and rectification in chemical production, the separation of substances is realized according to the different boiling points. The boiling point of 1-Nitro-2,3,4,6-Tetrafluorobenzene provides an important reference for the setting of process parameters.
The melting point is about -30 ° C. The melting point is the temperature at which a substance changes from solid to liquid. Knowing the melting point, in case of low temperature environment during storage and transportation, it can be judged based on the change of its physical state, so that appropriate protective measures can be taken to ensure the stability and safety of the substance.
Solubility, slightly soluble in water, but soluble in most organic solvents, such as ethanol, ether, acetone, etc. This difference in solubility is due to its molecular structure and polarity. Water is a polar solvent, and the molecular structure of 1-Nitro-2,3,4,6-Tetrafluorobenzene makes it slightly soluble because its polarity is different from that of water; the polarity and molecular structure characteristics of organic solvents are more compatible with 1-Nitro-2,3,4,6-Tetrafluorobenzene, so it is soluble. This solubility has a significant impact on the choice of reaction solvents in organic synthesis reactions, and suitable solvents can promote the reaction and improve the reaction yield.
The physical properties of 1 - Nitro - 2, 3, 4, 6 - Tetrafluorobenzene are of critical significance in the fields of chemical engineering and organic synthesis, whether it is material preparation, separation and purification, or storage and transportation, and are an important basis for related process operations and process design.
Is 1-Nitro-2,3,4, 6-Tetrafluorobenzene chemically stable?
The stability of the chemical properties of 1-nitro-2,3,4,6-tetrafluorobenzene depends on many reasons. This compound has nitro and fluorine atoms, which have a great influence on its chemical properties.
Nitro has strong electron-absorbing properties. This property reduces the electron cloud density of the benzene ring, making the benzene ring more vulnerable to attack by nucleophiles. Under suitable conditions, nitro groups can be reduced, such as iron and hydrochloric acid as reducing agents, and nitro groups can be converted into amino groups, which is an important conversion reaction in organic synthesis.
And fluorine atoms, which are extremely electronegative, are also strong electron-absorbing groups. Its presence not only enhances molecular polarity, but also results in high stability of fluorinated compounds due to high C-F bond energy. In 1-nitro-2,3,4,6-tetrafluorobenzene, fluorine atoms further reduce the electron cloud density of the benzene ring, and the electron cloud density of the ortho and para-sites on the benzene ring decreases more than that of the meta-sites, thus affecting the localization effect of nucleophilic substitution reactions.
However, its stability depends on the specific environment. Under normal temperature and pressure, and without special reagents or conditions, 1-nitro-2,3,4,6-tetrafluorobenzene is relatively stable. However, under extreme conditions such as strong reducing agent, strong acid, strong base or high temperature, its structure and properties will change. In case of strong reducing agent, nitro reduction; in case of high temperature, or initiate decomposition reaction, because the bond energy in the structure is not enough to maintain molecular stability at high temperature.
In summary, the stability of 1-nitro-2,3,4,6-tetrafluorobenzene is not absolute, and it is relatively stable at room temperature and pressure. However, under specific conditions, the chemical properties are variable, or various chemical reactions are initiated.
What is the production process of 1-Nitro-2,3,4, 6-Tetrafluorobenzene
1-Nitro-2,3,4,6-tetrafluorobenzene is an important organic compound in the chemical industry. Its production process is delicate and complex, involving several key steps.
At the beginning, fluorobenzene is often used as the base material, because its benzene ring structure is stable and contains fluorine atoms, which lays the foundation for subsequent reactions. Fluorobenzene is placed in a specific reactor, which is pre-prepared with strong nitrifying reagents, such as a mixture of concentrated nitric acid and concentrated sulfuric acid. This mixed acid is like the "vanguard army" of chemical reactions, and can precisely introduce nitro groups into the benzene ring. The reaction needs to be strictly controlled at temperature, generally in a low temperature environment, such as 0-5 ° C. If the temperature is too high, it is easy to cause a cluster of side reactions and the product is impure; if the temperature is too low, the reaction rate is slow and time-consuming.
After the nitrification reaction is completed, the obtained product is a mixture of nitrofluorobenzene. At this time, it needs to be carefully separated and purified to obtain pure 1-nitro-2,3,4,6-tetrafluorobenzene. Commonly used separation methods include distillation, extraction and column chromatography. The distiller, according to the difference in the boiling point of each component of the mixture, heats it to vaporize and condense successively to achieve the purpose of separation. Extraction uses the solubility of the solute in different solvents to extract the target product with a specific solvent. Column chromatography uses the adsorbent as the medium and the adsorption capacity of each component to achieve separation.
In the entire production process, safety and environmental protection are also of paramount importance. Strong nitrifying reagents are highly corrosive and oxidizing, and the operating procedures must be strictly followed during operation to prevent injury. The waste gas and waste liquid generated by the reaction must be properly handled and purified in accordance with environmental regulations, so as not to pollute the environment.
This is the approximate production process of 1-nitro-2,3,4,6-tetrafluorobenzene. Every link needs to be carefully controlled to obtain high-quality products.
1-Nitro-2,3,4, 6-Tetrafluorobenzene What are the precautions in storage and transportation
1-Nitro-2,3,4,6-tetrafluorobenzene is a very important chemical substance. When storing and transporting, many points need to be paid attention to.
First words storage. This substance should be placed in a cool and well-ventilated place. If the ambient temperature is too high, it can easily cause danger. If the ambient temperature is too high, or it can cause chemical reactions, there is even a risk of explosion. And it should be kept away from fire and heat sources. It is easy to burn or explode due to open flames and hot topics. In addition, it must be stored separately from oxidizing agents, reducing agents, alkalis, etc., and must not be mixed. This is because of its active chemical nature, mixed with other substances, easy to cause chemical reactions, resulting in safety accidents. At the same time, the storage place should be equipped with suitable materials to contain the leakage, in case of leakage, it can be properly handled in time.
As for transportation, there are also many precautions. Before transportation, make sure that the packaging is complete and the loading is safe. The packaging must be able to effectively prevent its leakage and volatilization, and can withstand certain collisions and vibrations. During transportation, the speed should not be too fast to prevent excessive bumps. It is also necessary to avoid sun and rain, due to direct sunlight and rain, or affecting its chemical stability. Escort personnel must be familiar with the nature of this substance and emergency treatment methods, and pay attention to the status of the goods at any time on the way. Once any abnormalities are found, such as damaged packaging, odor emission, etc., immediate measures should be taken or professional personnel should be contacted to deal with it.
In conclusion, 1-nitro-2,3,4,6-tetrafluorobenzene should be treated with caution when storing and transporting it, from environmental conditions to packaging, personnel, etc., in order to ensure its safety and avoid accidents.