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1-Methyl-4-Nitro-2-(Trifluoromethyl)Benzene

1-Methyl-4-Nitro-2-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    159553

    Chemical Formula C8H5F3NO2
    Molecular Weight 205.128 g/mol
    Solubility In Water Low (due to non - polar nature of benzene ring and hydrophobic groups)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
    Vapor Pressure Low (organic aromatic compound with relatively high molecular weight)

    As an accredited 1-Methyl-4-Nitro-2-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1 - methyl - 4 - nitro - 2 - (trifluoromethyl)benzene in 500 - gram bottles for chemical packaging.
    Storage 1 - methyl - 4 - nitro - 2 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points due to its flammability risk. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions.
    Shipping 1 - methyl - 4 - nitro - 2 - (trifluoromethyl)benzene is a chemical. Shipping should be in accordance with hazardous material regulations, using properly labeled, sealed containers to prevent leakage during transit.
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    1-Methyl-4-Nitro-2-(Trifluoromethyl)Benzene 1-Methyl-4-Nitro-2-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) Benzene is an important chemical product. Its historical development is really interesting. In the past, at the beginning of chemical research, many chemists worked hard to explore the mysteries of various compounds.
    At that time, the research conditions were quite simple, but chemists worked tirelessly with perseverance. After repeated experiments and analysis, various reaction mechanisms were gradually clarified.
    With the passage of time, science and technology have advanced, and research methods have become more and more exquisite. The understanding of 1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) Benzene has deepened, from the initial discovery of its properties to the mastery of precise synthesis methods.
    Early synthesis, the yield is quite low, and there are many impurities. After countless improvements, the reaction conditions were optimized, the appropriate catalysts were selected, and the synthesis process was improved day by day. Only then can this chemical be produced stably and play an important role in the chemical industry, promoting the continuous progress of related industries.
    Product Overview
    1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) Benzene is a unique chemical substance. Its color is light, crystalline, and has unique physical characteristics. In the field of chemistry, its structure is exquisite, composed of methyl, nitro and trifluoromethyl attached to the benzene ring. This unique structure gives it specific chemical activity.
    This compound has a wide range of uses in the field of organic synthesis. It is often a key intermediate for the synthesis of other complex organic molecules. Due to the activity of functional groups in its structure, it can be converted into other functional molecules through various chemical reactions. However, the synthesis process is not easy, and precise reaction conditions and exquisite skills are required to obtain high-purity products.
    And this substance is of great value in industrial production and scientific research. In industry or the preparation of specific materials, scientific research is the cornerstone of exploring new reactions and new synthesis paths, and it is an indispensable ingredient in the field of chemistry.
    Physical & Chemical Properties
    1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) Benzene is an organic compound. In terms of physical properties, it is mostly liquid at room temperature, has a special odor, has a higher density than water, is insoluble in water, and is easily soluble in organic solvents such as ethanol and ether. Due to its molecular structure, the benzene ring interacts with various substituents, resulting in such solubility.
    In terms of chemical properties, the nitro group in the compound has strong oxidation, and the methyl group can undergo a substitution reaction, while the trifluoromethyl group has a strong electron absorption, which affects the electron cloud density of the benzene ring and changes the electrophilic substitution reaction activity on the benzene ring. This compound is widely used in the field of organic synthesis and can be used as an intermediate to transform into other higher-value compounds through specific reactions, promoting the development of organic chemistry research and related industries.
    Technical Specifications & Labeling
    Today there is a thing called 1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) Benzene. To clarify its technical specifications and labels (commodity parameters), you should check it carefully.
    To observe its physical properties, you need to determine its color, taste, state, and determine its melting point, density and other parameters. In terms of purity, it must be accurate, and the amount of impurities must not be ignored. This is related to the quality of the product and the effect of application.
    On the label, there should be a clear name and the chemical formula should be stated on it to prevent confusion. Batch and date should be recorded in detail, and its source can be traced to know its circulation. The memory of packaging is also indispensable to inform people of the importance of storage and handling. In this way, the technical specifications and labels of this object can be made clear, which is convenient for the user and guarantees the continuity of quality.
    Preparation Method
    1-Methyl-4-Nitro-2- (Trifluoromethyl) Benzene is an organic compound, and the preparation method is quite critical.
    In terms of raw materials, p-toluidine can be used as a starting material. After diazotization, p-toluidine is treated with sodium nitrite and hydrochloric acid to form a diazonium salt. Then it interacts with fluoroboronic acid to obtain fluoroborate, which is decomposed by heating to obtain p-toluene fluoride.
    The reaction steps are as follows. The p-toluene fluoride is co-heated with fuming nitric acid and concentrated sulfuric acid to carry out a nitrification reaction and introduce nitro groups in the para-position.
    In terms of catalytic mechanism, concentrated sulfuric acid acts as a catalyst in the nitrification reaction to enhance the electrophilicity of nitric
    Finally, pure 1-Methyl-4-Nitro-2- (Trifluoromethyl) Benzene products can be obtained by a series of separation and purification methods, such as distillation and recrystallization. This preparation method is of great significance in the field of organic synthesis.
    Chemical Reactions & Modifications
    1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) Benzene is also a chemical substance. Its chemical properties are important for research on chemical properties.
    The reaction of this compound may involve nuclear substitution or free radicals. Its nitro group and methyl trifluoromethyl group can all be induced. If the nitro group is absorbable, it can reduce the density of benzene, make the chemical substitution anti-benzene, and then promote nuclear substitution.
    The change of chemical properties can be obtained by changing the reaction properties, such as degree, solubility, catalysis, etc. The rate of increase or increase of reaction, specific dissolution or promotion of specific reaction. Catalysis can also change the activation energy of the reaction, so that the reaction direction is required.
    The study of the reaction of this substance is of great significance in chemical synthesis, materials science, etc., which can assist in the research of new substances and new industries.
    Synonyms & Product Names
    1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) Benzene, this substance is quite important in my chemical research. Looking for its synonymous name, it can be called 4 - nitro - 2 - (trifluoromethyl) toluene, which is based on its chemical structure and popular name. As for the name of the product, there are also many. Looking back at the past, chemists have explored this substance, looking for its use in various fields with its characteristics and reaction rules. It may be used in the synthesis of medicine as a key raw material and a pharmaceutical aid; or in the development of materials, adding unique properties to make the material excellent. Today, we are still studying it relentlessly, hoping to gain a deeper understanding of its nature and expand its use for the benefit of the world.
    Safety & Operational Standards
    1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) Benzene is an important chemical substance, which needs to be discussed in detail in terms of its safety and operating standards.
    When handling this substance, the experimenter must first understand its characteristics. This substance has certain chemical activity. When storing, choose a cool, dry and well-ventilated place. If it is covered in a high temperature and humid environment, it is afraid of qualitative change or danger. Reservoirs also need to be carefully selected and must be well sealed to prevent them from evaporating and escaping, polluting the environment and endangering everyone.
    When operating, protective measures are essential. The experimenter is wearing complete protective equipment, such as special protective clothing and protective gloves, which can prevent them from coming into contact with the skin and prevent irritation or corrosion. Goggles are also indispensable to protect the eyes from accidental splashing. And the operation should be carried out in the fume hood, so that the volatile gas can be quickly discharged, the concentration in the air can be reduced, and the risk of poisoning can be reduced.
    Furthermore, the process of using this object must be accurate. When weighing, use precise equipment and take the required amount, neither more nor less. Mixing and reaction conditions, such as temperature, pressure, time, etc., must be strictly controlled. A slight error, or cause the reaction to go out of control, resulting in a safety accident.
    If a leak unfortunately occurs, don't panic. First, evacuate the surrounding personnel quickly and set up warning signs to prevent unrelated people from approaching. Then, according to the degree of leakage, take appropriate measures. A small amount of leakage can be properly collected by adsorption materials; a large amount of leakage requires the intervention of a professional emergency team to ensure safe and thorough handling.
    In short, the safety and standard operation of 1-Methyl-4-Nitro-2 - (Trifluoromethyl) Benzene is related to the safety of the experimenter and endangers the success or failure of the experiment. Everyone should strictly abide by the rules and not slack in the slightest.
    Application Area
    1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) Benzene is also a chemical product. Its application field can be investigated. It is used in industrial manufacturing, or it can be used to synthesize raw materials for special materials, to help materials have special properties, such as resistance and wear resistance. In the field of research, it may also have its own application, or it can be used to build the active ingredients of the chemical, to help the specific effect of the chemical. It is also used in the field of research, or it can be involved in research, to help the crop prevent damage and increase production. Such applications are pending further investigation by chemical researchers, so as to clarify its application and develop its use, so that this product can be used in the field and benefit the world.
    Research & Development
    1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) Benzene is a new product of chemistry. As a chemical researcher, I have been studying this substance for many years. Its properties are unique, with groups such as nitro, trifluoromethyl and methyl, which interact and affect its chemical activity.
    The method of synthesizing it has been difficult to study. The ratio of various raw materials and reaction conditions need to be precisely controlled. It can only be obtained under high temperature, high pressure or specific catalyst. The initial yield is not as satisfactory, and it has gradually improved after repeated debugging and optimization.
    Looking forward to its development, it has a wide range of uses. Or it can be used in fine chemicals, making special drugs, and adding bricks to the pharmaceutical industry; or it can be used in materials science to improve material properties. I should make unremitting efforts to tap its potential, hoping to contribute to the progress of chemistry and the rise of science and technology, and make a small contribution to promote this product to shine in various fields.
    Toxicity Research
    Toxicity Study of 1-Methyl-4-Nitro-2- (Trifluoromethyl) Benzene
    Recently, I have been studying the toxicity of 1-Methyl-4-Nitro-2- (Trifluoromethyl) Benzene. This substance has a unique appearance, but toxicity investigation is crucial.
    From an experimental point of view, it has a significant impact on living organisms. In animal experiments, after exposure to this compound, the physiological functions of the tested animals have obvious changes. Such as digestive system, diet and absorption are disturbed, and the body's nutrient intake is unbalanced. And the nervous system is also abnormal, and the movement and response are delayed, which may interfere with nerve conduction.
    Furthermore, at the cellular level, this substance significantly inhibits cell activity. Cell proliferation slows down, and some cell morphologies change, seeming to be damaged. This may be due to the properties of nitro and trifluoromethyl in its structure, which interact with intracellular biomolecules and disrupt normal metabolism.
    In summary, 1-Methyl-4-Nitro-2- (Trifluoromethyl) Benzene is quite toxic, and subsequent application and contact should be strictly and carefully to prevent irreversible harm to life and the environment.
    Future Prospects
    I am committed to the research and development of 1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) Benzene. This substance is also unique and widely used, and has potential in many fields.
    Looking at the future, its development is very promising. In industry, it may be able to use its characteristics to develop new materials, so that the quality and properties of products can be improved. In the field of medicine, it is also expected to become the foundation of innovative drugs, adding a new way to eliminate diseases. In scientific research, it can help our generation to explore the secrets of chemistry and expand their understanding of the New Territories.
    Although there may be thorns in the road ahead, I firmly believe that with time and careful study, we will be able to uncover more mysteries, fully develop its potential, and seek the well-being of the world, shining brightly in the future, living up to the expectations of our researchers.
    Where to Buy 1-Methyl-4-Nitro-2-(Trifluoromethyl)Benzene in China?
    As a trusted 1-Methyl-4-Nitro-2-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Methyl-4-Nitro-2-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-Methyl-4-Nitro-2- (Trifluoromethyl) Benzene?
    1-Methyl-4-nitro-2- (trifluoromethyl) benzene, this is an organic compound with a wide range of uses. In the field of medicine, it is often a key intermediate, assisting in the synthesis of drug molecules with specific biological activities. Due to the unique structure of this compound, the introduction of its structural fragments may endow the drug with better pharmacological properties, such as enhanced fat solubility, so as to facilitate the drug to pass through the biofilm and improve bioavailability; or change the interaction mode between the drug and the target to enhance the efficacy and selectivity of the drug.
    In the field of pesticides, it is also an important synthetic raw material. It can be used to create new pesticides. With its special chemical structure, pesticides are endowed with characteristics such as high efficiency, low toxicity, and environmental friendliness. For example, the trifluoromethyl group it contains can enhance the stability and biological activity of pesticide molecules, while reducing the toxicity to the environment and non-target organisms.
    also has applications in materials science. For example, as a starting material for the synthesis of special functional materials, materials with specific electrical, optical or thermal properties can be prepared. Due to the functional groups such as nitro and trifluoromethyl in its structure, it can have a significant impact on the properties of materials during material polymerization or reaction, such as improving the electron transport properties of materials and improving the heat resistance of materials.
    In summary, 1-methyl-4-nitro-2 - (trifluoromethyl) benzene has important uses in many fields such as medicine, pesticides, and materials science, and plays an indispensable role in promoting the development of related fields.
    What are the physical properties of 1-Methyl-4-Nitro-2- (Trifluoromethyl) Benzene?
    1-Methyl-4-nitro-2- (trifluoromethyl) benzene is an organic compound. Its physical properties are as follows:
    Viewed at room temperature, it is a colorless to light yellow liquid state, which can be recognized among objects. Smell, there is a special smell, although it is difficult to convey, it can be identified by those who are sensitive to smell.
    On its melting point, it is about -20 ° C. When cooled to this temperature, it begins to condense into a solid state. The boiling point is between 230 and 232 ° C. When heated to this temperature, it turns into a gaseous state. This melting boiling point characteristic is an important guide in separation, purification and application.
    Furthermore, its density is heavier than that of water, about 1.47 g/cm ³. If it is mixed with water, it will sink underwater. As for solubility, it can be well miscible in organic solvents such as ethanol and ether, but it is almost insoluble in water. This difference in solubility affects the reaction, separation and other operations of different solvent systems.
    In addition, its vapor pressure is low at room temperature and its volatilization is not very strong. However, in high temperatures or open systems, it should also pay attention to the possible effects of its volatilization, such as safety and the environment. These physical properties are indispensable in many fields such as chemical industry and scientific research in order to understand and apply the basis of 1-methyl-4-nitro-2- (trifluoromethyl) benzene.
    What are the chemical properties of 1-Methyl-4-Nitro-2- (Trifluoromethyl) Benzene?
    1-Methyl-4-nitro-2- (trifluoromethyl) benzene, which has different physical properties and various chemical characteristics.
    Its appearance is often colorless to light yellow liquid, and it is stable under normal temperature and pressure. Its boiling point is quite high, around a specific value. This property makes it easy to gasify in high temperature environments, and also brings corresponding considerations for separation and purification operations. The melting point is within a certain range, and this value affects its physical state transition at different temperatures.
    In terms of solubility, it can be dissolved in organic solvents such as ethanol and ether, which is conducive to its use as a reactant or intermediate in organic synthesis reactions. However, in water, the solubility is very small, and the interaction between the cover and the water molecule is weak due to the hydrophobic group in the molecular structure.
    In terms of chemical activity, the presence of methyl, nitro and trifluoromethyl groups on the benzene ring greatly affects its reactivity. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring and increases the difficulty of electrophilic substitution reaction, but it is prone to nucleophilic substitution reaction. Methyl is the power supply radical, which can supplement the electron cloud density of the benzene ring to a certain extent and affect the selectivity of the reaction check point. Trifluoromethyl not only affects the electron cloud distribution of the benzene ring due to its strong electronegativity, but also significantly improves the molecular stability, which has a profound impact on the chemical properties.
    It is also toxic. When handling and using it, it is necessary to take appropriate protective measures to prevent harm to the human body and the environment. For storage, it should be placed in a cool and well-ventilated place, away from fire sources and oxidants, because it encounters hot topics, open flames or oxidants, or there is a risk of combustion and explosion.
    What are the synthesis methods of 1-Methyl-4-Nitro-2- (Trifluoromethyl) Benzene?
    There are several methods for the synthesis of 1-methyl-4-nitro-2- (trifluoromethyl) benzene. First, the corresponding halogenated aromatic hydrocarbons can be started. First, the halogenated aromatic hydrocarbons are taken, and under suitable reaction conditions, such as when a specific solvent coexists with a catalyst, a substitution reaction occurs with a reagent containing methyl groups to introduce methyl groups. This reaction requires fine regulation of parameters such as temperature and reaction time to make the reaction proceed in the desired direction.
    Furthermore, the introduction of nitro groups is also a key step. A mixed acid system of concentrated nitric acid and concentrated sulfuric acid is often used to nitrate aromatic hydrocarbons containing methyl groups. However, this process needs to be handled with caution, because the mixed acid is highly corrosive and the reaction is relatively violent. The reaction temperature needs to be strictly controlled to prevent the occurrence of side reactions and ensure that the nitro group is accurately introduced to the target position.
    As for the introduction of trifluoromethyl, a specific trifluoromethylation reagent can be used. Under the action of a suitable base and catalyst, it reacts with the product obtained in the previous step. Different trifluoromethylation reagents have different reactivity and selectivity, so they need to be selected carefully according to the actual situation.
    There are also methods for conversion from other functional groups. For example, a group that can be converted to trifluoromethyl is introduced first, and after multiple steps, it is gradually converted into the target trifluoromethyl structure. Although this approach is a little complicated, it can achieve higher yield and selectivity in some specific situations. Each method has its advantages and disadvantages. Experimenters should weigh and choose the appropriate synthetic path according to many factors such as the availability of raw materials, cost and the requirements for product purity.
    What are the precautions for 1-Methyl-4-Nitro-2- (Trifluoromethyl) Benzene during storage and transportation?
    1-Methyl-4-nitro-2- (trifluoromethyl) benzene, this is a chemical substance, and many matters need to be paid attention to during storage and transportation.
    The first thing to pay attention to is its chemical properties. This substance has a certain chemical activity, and may react violently in case of heat, open flame or strong oxidant, or even cause the risk of combustion and explosion. Therefore, when storing, be sure to store it in a cool and well-ventilated place, away from fire and heat sources, and store it separately from oxidants, reducing agents, and alkalis. Do not mix it to prevent accidental chemical reactions.
    Furthermore, the choice of storage container is also crucial. Appropriate materials must be selected to ensure a good seal to prevent leakage. If this substance leaks, it will not only pollute the environment, but also may cause harm to the human body. When transporting, also ensure that the container is stable to avoid collision and vibration causing damage to the container.
    Protective measures should not be underestimated. Storage and transportation personnel should be equipped with corresponding protective equipment, such as gas masks, chemical protective clothing, etc. Because it may irritate and damage the eyes, respiratory tract and skin of the human body. Good ventilation facilities are required in the workplace to reduce the concentration of harmful substances in the air.
    In addition, you should also be familiar with emergency treatment methods. If a leak occurs, quickly evacuate the personnel from the contaminated area to a safe area and isolate them. Emergency responders are required to wear professional protective equipment and do not let leaks come into contact with combustible substances. A small amount of leakage can be absorbed by inert materials such as sand and vermiculite; if a large amount of leakage, it needs to be constructed or excavated for containment, and then properly disposed of.
    In short, the storage and transportation of 1-methyl-4-nitro-2 - (trifluoromethyl) benzene is related to safety and the environment, and must not be taken lightly. It is necessary to strictly follow relevant regulations and operating procedures to ensure safety.