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What is the main use of 1-Methyl-3- (1,1,2,2-Tetrafluoroethoxy) Benzene?
1-Methyl-3- (1,1,2,2-tetrafluoroethoxy) benzene, this substance is widely used in the field of chemical industry.
First, it is often a key intermediate in the synthesis of medicine. Due to the special structure of tetrafluoroethoxy, it is endowed with unique chemical activity and stability. Taking the synthesis of a new type of antibacterial drug as an example, 1-methyl-3- (1,1,2,2-tetrafluoroethoxy) benzene can introduce specific functional groups through a series of reactions to build the core framework of the drug, which lays the foundation for the realization of antibacterial activity. The benzene ring and fluoroethoxy group in its structure may affect the lipophilicity and electron cloud distribution of the drug in the interaction between the drug and the target, thereby optimizing the pharmacological properties of the drug.
Second, in the field of materials science, it also has extraordinary performance. In the preparation of high-performance polymers, it can be introduced into the polymer chain as a monomer. Due to its fluorine-containing structure, it can significantly improve the properties of the polymer, such as improving the chemical resistance, heat resistance and low surface energy of the polymer. For example, special plastics used in the synthesis of this substance can be used to manufacture the lining of chemical equipment, which can resist the erosion of various chemical media with its excellent corrosion resistance; or in the aerospace field, with its good heat resistance and low surface energy, to improve the performance of aircraft components.
Third, in the preparation of fine chemical products, 1-methyl-3- (1,1,2,2-tetrafluoroethoxy) benzene also plays an important role. In the development of high-end coatings, the addition of this substance can improve the film formation, wear resistance and weather resistance of coatings. The fluorine-containing group can reduce the surface tension of the coating surface, making it easier for the coating to spread evenly, forming a dense protective film, thereby prolonging the service life of the coated object.
In summary, 1-methyl-3- (1,1,2,2-tetrafluoroethoxy) benzene has important uses in medicine, materials, fine chemicals and other fields, and is indispensable for the development of modern industry.
What are the physical properties of 1-Methyl-3- (1,1,2,2-Tetrafluoroethoxy) Benzene
1-Methyl-3- (1,1,2,2-tetrafluoroethoxy) benzene is one of the organic compounds. Its physical properties are quite worthy of detailed investigation.
Looking at its properties, under normal temperature and pressure, this substance is generally a colorless and transparent liquid, with a clear texture, like a clear spring, without obvious impurities or suspended solids, which gives people a sense of purity.
When it comes to boiling point, due to the influence of intermolecular forces, its boiling point is within a specific range. Generally speaking, at standard atmospheric pressure, the boiling point is about a certain range, and this value is formed by the interaction between atoms in its molecular structure, such as van der Waals force, hydrogen bond, etc. When the outside temperature gradually rises to the boiling point, the substance gradually converts from the liquid state to the gaseous state, just like ice melts into water, and water rises into steam, undergoing a phase transition.
Melting point is also one of its important physical properties. Under a certain low temperature condition, the substance will solidify from liquid state to solid state, and this temperature is its melting point. The value of the melting point is also closely related to the molecular structure. The regular degree of molecular arrangement and the strength of the interaction force between atoms all affect the melting point.
Its density also has characteristics. At room temperature, the mass per unit volume is relatively stable. This density value reflects the compactness of the molecules of the substance and the relative mass of the atoms. Through the determination of density, it can play a key guiding role in practical applications, such as the separation and purification of substances.
In terms of solubility, 1-methyl-3- (1,1,2,2-tetrafluoroethoxy) benzene exhibits a certain solubility in organic solvents. It can be miscible with some organic solvents, such as ethanol and ether, just like a fish entering water. However, the solubility in water is very small, because the polarity of the substance molecule is quite different from the polarity of the water molecule, and follows the principle of "similar miscibility".
In addition, the volatility of the substance cannot be ignored. Due to the fact that the intermolecular force is not extremely strong, it has a certain degree of volatility at room temperature and can slowly dissipate in the air, just like the fragrance of flowers, which also requires specific storage and use.
Is 1-Methyl-3- (1,1,2,2-Tetrafluoroethoxy) Benzene Chemically Stable?
The stability of the chemical properties of 1-methyl-3- (1,1,2,2-tetrafluoroethoxy) benzene is related to many aspects. This compound contains specific functional groups, and its stability needs to be examined in detail.
In terms of its structure, the benzene ring has a conjugated system, which usually gives the compound a certain stability. The methyl group attached to the benzene ring has a slight impact on the distribution of its electron cloud, but the stability effect is not huge. The introduction of 1,1,2,2-tetrafluoroethoxy adds new properties to the molecule. The fluorine atom has strong electronegativity, which can attract electrons, so that the carbon-oxygen bond electron cloud connected to it is biased towards fluorine, causing the bond energy to change.
In chemical reactions, the stability of this compound may be present in different scenarios. Under mild conditions, if there is no strong oxidizing agent, reducing agent or special catalyst, its benzene ring and surrounding substituents may remain relatively stable. In case of extreme conditions such as high temperature, strong acid, and strong base, or initiate a chemical reaction. In case of strong acid, or cause ether bonds to break, causing molecular structure changes. In case of strong oxidizing agent, methyl may be oxidized.
In addition, its stability is also restricted by environmental factors. Under light, or cause luminescent chemical reactions, causing bond homogeneity or heterocleavage, destroying molecular stability. In high temperature environments, the thermal motion of molecules intensifies, or reactions occur, damaging its stability.
In summary, the stability of 1-methyl-3- (1,1,2,2-tetrafluoroethoxy) benzene is not absolute and can be maintained under specific conditions. However, in special cases, the stability is easily broken, chemical reactions occur, and its chemical form is changed.
What is the production process of 1-Methyl-3- (1,1,2,2-Tetrafluoroethoxy) Benzene?
The production process of 1-methyl-3- (1,1,2,2-tetrafluoroethoxy) benzene requires several steps to complete.
The first is prepared as the starting material. M-cresol and 1,1,2,2-tetrafluoroethane are often taken as the base materials. M-cresol is easily available in the chemical industry, with a typical phenolic structure. The methyl and hydroxyl groups are distributed on the phenyl ring. This structure is the basis for subsequent reactions. 1,1,2,2-tetrafluorochloroethane contains a fluorohalogenated hydrocarbon structure, and the halogen atom activity is appropriate, which is conducive to the progress of nucleophilic substitution.
Next, it is put into the reaction kettle, and a base is added as the catalyst. Potassium carbonate and the like are often selected. The action of the base is to capture the hydrogen of the m-cresol hydroxyl group and form the phenoxy anion, which has strong nucleophilicity. At appropriate temperature and pressure, the phenoxy anion nucleophilic attacks the carbon site attached to the chlorine atom of 1,1,2,2-tetrafluoroethane, and the chlorine atom leaves, and then forms a C-O bond to obtain a crude product of 1-methyl-3- (1,1,2,2-tetrafluoroethoxy) benzene. This step is controlled in a moderate temperature range. If it is too high, side reactions will occur, and if it is too low, the reaction will be delayed. The pressure also needs to be adjusted to ensure that the reactants are in an appropriate phase and facilitate contact reaction.
The crude product has been obtained, and it can be separated and purified. After distillation, according to the difference of boiling point of each component, the unreacted raw materials, by-products and target products are preliminarily separated. After extraction, a suitable organic solvent is selected to extract the target product from the organic phase and separate it from impurities. Then, by column chromatography and other fine means, trace impurities are removed to obtain high-purity 1-methyl-3- (1,1,2,2-tetrafluoroethoxy) benzene.
The whole production process, raw material selection, reaction condition control, separation and purification methods are all required. It is related to the purity and yield of the product, and fine handling is required to obtain high-quality 1-methyl-3- (1,1,2,2-tetrafluoroethoxy) benzene.
What is the price range of 1-Methyl-3- (1,1,2,2-Tetrafluoroethoxy) Benzene in the market?
I do not know for sure the price range of 1 - Methyl - 3 - (1, 1, 2, 2 - Tetrafluoroethoxy) Benzene in the market. This compound may be a relatively uncommon organic synthesis intermediate, and its price is often affected by many factors.
The cost of raw materials is one of the main reasons. If the starting materials required to synthesize this compound are difficult or expensive to obtain, such as some fluorinated raw materials, the high price will cause the price of the final product to rise. And the complexity of the synthesis process also affects. If multiple steps are required, harsh reaction conditions, such as specific catalysts, high temperature and high pressure, etc., will increase the production cost and then raise the market price.
Furthermore, the market supply and demand relationship is extremely critical. If there is a surge in demand for an industry, but the supply is limited, such as in the fields of medicine and material science, there are few manufacturers, and the supply is in short supply, the price is easy to rise; on the contrary, if the demand is weak and the supply is excessive, the price will fall.
In addition, the scale of production is also related to the price. In large-scale production, due to the scale effect, the unit production cost may be reduced, and the price is expected to be more affordable; in small-scale production, the unit cost is high, and the price may be higher.
There is also the impact of market competition. If multiple companies produce this product, the competition is fierce, and the market share may be suppressed; conversely, if only a few manufacturers control the production, their pricing power will be strong, and the price may be high.
In summary, due to the lack of detailed market surveys and related data, it is difficult to give the exact price range. For details, you can consult chemical product suppliers, browse professional chemical trading platforms or consult industry experts to obtain more accurate price information.