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1-Methyl-2-Trifluoromethyl-Benzene

1-Methyl-2-Trifluoromethyl-Benzene

Hongda Chemical

Specifications

HS Code

852387

Chemical Formula C8H7F3
Molar Mass 160.14 g/mol
Appearance Colorless liquid
Boiling Point 140 - 142 °C
Melting Point Unknown
Density 1.12 g/cm³
Solubility In Water Insoluble
Vapor Pressure Unknown
Flash Point 28 °C
Refractive Index 1.427

As an accredited 1-Methyl-2-Trifluoromethyl-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500 - gram bottle packaging for 1 - methyl - 2 - trifluoromethyl - benzene chemical.
Storage 1 - methyl - 2 - trifluoromethyl - benzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive chemicals. Use a storage facility compliant with safety regulations to avoid potential fire, explosion, or chemical reaction risks.
Shipping 1 - methyl - 2 - trifluoromethyl - benzene should be shipped in tightly sealed, corrosion - resistant containers. Label packages clearly with hazard warnings. Transport under conditions preventing heat, ignition sources, and ensure compliance with chemical shipping regulations.
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1-Methyl-2-Trifluoromethyl-Benzene 1-Methyl-2-Trifluoromethyl-Benzene
General Information
Historical Development
1 - Methyl - 2 - Trifluoromethyl - Benzene is also an organic compound. It has become increasingly important in the field of chemistry. Looking back in the past, chemists studied and explored the characteristics of such compounds for the first time. At that time, science and technology were not as developed as they are today, and the road of inquiry was full of thorns.
However, the ambition of scholars has not changed. After years of hard work, the understanding of its structure and properties has gradually deepened. It was able to produce this compound in an exquisite way. With the passage of time and the advancement of technology, the synthesis method has become more and more perfect, and the yield has also increased.
Therefore, 1 - Methyl - 2 - Trifluoromethyl - Benzene is widely used in chemical, pharmaceutical and other industries. Looking at its historical development, it is like a shining star, gradually shining in the chemical firmament, paving the foundation for the development of future generations.
Product Overview
1 - Methyl - 2 - Trifluoromethyl - Benzene is an organic compound. It is a colorless liquid with a special odor. This compound contains a benzene ring structure, and methyl and trifluoromethyl are divided into two sites of the benzene ring. Its physical properties, boiling point and melting point are fixed, and it has a certain density and solubility.
In terms of chemical properties, it has unique reactivity due to the presence of trifluoromethyl in its structure. It can participate in many organic reactions, such as electrophilic substitution reactions. Due to the strong electron absorption of trifluoromethyl, the electron cloud density of the benzene ring decreases, and the reaction check point is biased. It can also be used to synthesize a variety of fine chemicals, and has important application potential in the fields of medicine, pesticides, and materials science. Chemists can use a variety of synthetic pathways to produce this compound, and through ingenious reaction design and conditioning, the ideal yield and purity can be obtained.
Physical & Chemical Properties
1 - Methyl - 2 - Trifluoromethyl - Benzene is also an organic compound. Its physical and chemical properties can be studied. Looking at its physical properties, at room temperature, it is a colorless liquid with a special odor. Its boiling point is suitable for a specific value, which is related to the balance of its intermolecular force and vapor pressure. As for chemical properties, it has unique reactivity because it contains methyl and trifluoromethyl groups. Methyl groups can participate in common hydrocarbon reactions. Trifluoromethyl groups change the distribution of molecular electron clouds because of their strong electronegativity, and have unique manifestations in nucleophilic and electrophilic reactions. This compound can be used as a key intermediate in the field of organic synthesis. With its characteristics, it can build a variety of complex structures and has potential applications in various fields such as medicine and materials. It is urgent for us to explore its properties and applications.
Technical Specifications & Labeling
1 - Methyl - 2 - Trifluoromethyl - Benzene is an important chemical raw material. Its preparation process must be in accordance with specific technical specifications and standards (product parameters).
The selection of the first heavy raw materials must be pure and free of impurities, in line with the corresponding standards. When reacting, temperature and pressure control are crucial. In a specific reactor, the raw materials are mixed in a precise ratio, heated to a suitable temperature, maintain a stable pressure, and promote their full reaction.
Product identification (product parameters) should specify key information such as composition, purity, physical and chemical properties. Purity needs to reach a specific high standard, and impurity content is strictly controlled at a very low level. The packaging should also be clearly marked to facilitate identification and safe use.
In this way, high-quality 1-Methyl-2-Trifluoromethyl-Benzene products can be obtained to meet the needs of all parties.
Preparation Method
In order to prepare 1 - Methyl - 2 - Trifluoromethyl - Benzene, it is necessary to study the raw materials and production process, reaction steps and catalytic mechanism in detail.
The preliminary raw materials are based on benzene derivatives and fluorine-containing reagents, etc. This is the main starting point. The production process follows the usual method of organic synthesis and is formed by multi-step reaction.
The reaction step is the conversion of the first functional group, and the halogen atom is introduced at a specific position in the benzene ring by halogenation reaction to lay the foundation for the subsequent fluorination. Next, the fluoride-containing reagent is used for fluorination reaction, and the temperature, time and proportion of the reactants are carefully controlled. The halogen atom is replaced by trifluoromethyl. This step requires precise operation to avoid side reactions.
Catalytic mechanism is also the key. Selection of suitable catalysts, such as metal catalysts or specific organic catalysts, can increase the reaction rate and extract product purity. The catalyst can reduce the activation energy of the reaction and make the reaction easier.
Preparation of 1 - Methyl - 2 - Trifluoromethyl - Benzene, raw materials, processes, reactions and catalysis, interlocking, fine to get the best product.
Chemical Reactions & Modifications
Taste the wonders of chemical industry, related to reaction and modification, which is really the important task of the academic community. Today there is 1 - Methyl - 2 - Trifluoromethyl - Benzene, and the investigation of its reaction and modification is of great value.
The reaction can be viewed through specific conditions, such as selecting a suitable catalyst, controlling a precise temperature, and making it come into contact with various reagents. In this process, the breaking and formation of chemical bonds follow the laws of chemistry. Or due to substitution reactions, new groups are introduced, causing its structure to change.
As for modification, the purpose is to optimize its properties. It can be used to modify the molecular structure to make it have better stability, or to change the chemical activity to meet various needs. Such as for the preparation of special materials, to improve its weather resistance, solubility, etc.
For our chemical researchers, the detailed study of the reaction and modification of 1-Methyl-2-Trifluoromethyl-Benzene can contribute to the chemical industry and promote it to continue to advance to a higher level.
Synonyms & Product Names
1 - Methyl - 2 - Trifluoromethyl - Benzene is an organic compound with a wide range of uses in the chemical industry. Exploring its synonyms and trade names is an important part of chemical research.
Although this specific compound is not contained in ancient books and documents, it is also inspired by the way ancient people named and nicknamed substances. Today's chemical nomenclature is based on scientific structural analysis, and in the past it was based on appearance, source or use.
According to the structure of this compound, it contains methyl and trifluoromethyl. If it is according to the ancient meaning, it may be named after its unique combination of chemical groups. From the perspective of use, if it is used in a specific chemical process or product, it may be named according to the relevant application.
Although there is no exact correspondence between ancient sayings, if the perspective of the ancients, or according to their characteristics, can be endowed with synonyms and trade names with both symbolic and cultural connotations, it is also of far-reaching significance for the inheritance and development of chemical research and application.
Safety & Operational Standards
1 - Methyl - 2 - Trifluoromethyl - Benzene Safety and Operation Specifications
Husband 1 - Methyl - 2 - Trifluoromethyl - Benzene is an important substance in chemical research. The process of its experiment and production, safety and operation standards are of paramount importance and cannot be ignored.
#Safety Matters
This substance is volatile to a certain extent, and its vapor may irritate the eyes, respiratory tract and other parts. Therefore, when operating, in a well-ventilated place, it is advisable to prepare ventilation equipment, such as a fume hood, to dissipate steam and prevent it from accumulating and endangering the person.
Because it may be flammable, it should be kept away from fire and heat sources, and there should be no open flames in the operation room. Store in a cool, dry place and keep away from reactants such as oxidants to prevent fire and explosion.
Operators must wear appropriate protective equipment. If wearing protective glasses, you can protect your eyes from steam damage; wear protective clothing to protect against contact with the skin; wear protective gloves to prevent hand contamination.
#Operating instructions
When using 1-Methyl-2-Trifluoromethyl-Benzene, the action should be slow and stable to prevent splashing. Measure the appliance, when accurate, to meet the experimental requirements. When pouring, it should be along the container wall, do not let the liquid splash.
During the experiment, the reaction conditions must be strictly controlled. Temperature, pressure and other factors can affect the process and products of the reaction. If heating the reaction, use suitable heating equipment and monitor the temperature with a thermometer. Do not make the temperature too high and cause the reaction to get out of control.
After use, the remaining 1 - Methyl - 2 - Trifluoromethyl - Benzene should be properly stored and not discarded at will. The utensils used should also be cleaned in time to remove the residue for next use.
In short, in the operation of 1 - Methyl - 2 - Trifluoromethyl - Benzene, it is necessary to strictly abide by safety and operating standards to ensure the smooth operation of the experiment, protect the safety of the human body, and avoid accidents.
Application Area
1 - Methyl - 2 - Trifluoromethyl - Benzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediary to help create new drugs or bring opportunities for the treatment of difficult diseases. In the field of materials science, its unique chemical structure can give materials specific properties, such as enhancing the stability and corrosion resistance of materials, and is used in the preparation of high-end materials. In the field of fine chemicals, it can be used to synthesize various special chemicals and provide a variety of raw material options for industrial production. In the development process of the chemical industry, it plays an indispensable position and is indeed a compound with broad application prospects.
Research & Development
I am committed to the research of 1 - Methyl - 2 - Trifluoromethyl - Benzene. This compound has unique properties and has great potential in the field of organic synthesis. At the beginning, I explored its preparation method, but after many attempts, due to the harsh reaction conditions or the difficulty of raw materials, I encountered repeated setbacks. However, I have persevered and studied unremitting.
After repeated experiments, a feasible path was finally obtained to optimize the reaction parameters and improve the yield. Its physicochemical properties were also investigated in detail to explore its stability and activity in different environments.
As for the application and expansion, consider its possibility in the development of new materials and drugs. After much exploration, it was found that it has unique advantages in the construction of specific drug molecules, which is expected to bring new opportunities to the field of medicine. I will continue to cultivate deeply, hoping to promote the further development of this compound and make modest contributions to academia and industry.
Toxicity Research
The toxicity of 1 - Methyl - 2 - Trifluoromethyl - Benzene was studied. This substance is related to people's livelihood and health, so it was investigated in detail.
After many experiments, its effects on various organisms were observed. In animal experiments, at small doses, the test animals gradually showed abnormal behavior, or showed signs of fatigue and eating less. With a slight increase in dose, some organs showed signs of disease, especially the liver and kidney.
And observe its diffusion and transformation in the environment. In air, water and soil, its stability is quite high, and it can be enriched in organisms. In the long run, it may be harmful to ecological balance and human survival environment.
In summary, 1 - Methyl - 2 - Trifluoromethyl - Benzene has significant toxicity, and it is urgent to find effective prevention and control measures to reduce its harm to all living beings and the environment, and to ensure the peace of the world and the reproduction of all things.
Future Prospects
1 - Methyl - 2 - Trifluoromethyl - Benzene, this is the chemical substance I have been researching recently. Looking at the properties of this substance, its structure is unique, and it has both methyl and trifluoromethyl. The two interact on the benzene ring, or can derive many wonderful chemical properties.
Looking to the future, its application prospects are quite promising. In the field of materials, it may be possible to obtain new materials with excellent properties, such as polymers with excellent weather resistance and chemical stability, for use in high-end building materials and aerospace equipment. In the field of medicine, because fluorine-containing structures often have special biological activities, this substance may become a key intermediate for the development of new drugs, bringing hope to conquer difficult diseases.
We should study it relentlessly, explore its potential, and hope that in the future, we can fully utilize the advantages of this material, benefit the world, live up to the original intention of our generation's scientific research, open up a path for the unknown, lead the direction of science and technology, and hope that it will shine in the future and contribute to the progress of human civilization.
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Frequently Asked Questions

As a leading 1-Methyl-2-Trifluoromethyl-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Methyl-2-Trifluoromethyl-Benzene?
1-Methyl-2-trifluoromethyl-benzene, this substance has a wide range of uses. In the chemical industry, it is often used as an intermediate in organic synthesis. Due to its special structure, it contains methyl groups and trifluoromethyl groups, which endows it with unique chemical properties and can participate in many organic reactions to prepare other organic compounds.
For example, in pharmaceutical synthesis, 1-methyl-2-trifluoromethyl-benzene can be converted into biologically active substances or potential pharmaceutical components through a specific reaction path. Its unique structure helps to improve the fat solubility and stability of drug molecules, which is greatly helpful for the development of new drugs.
In the field of materials science, it also has important applications. Using this as a raw material, through specific polymerization or modification methods, polymer materials with specific properties can be obtained. Such materials may have good chemical resistance and thermal stability, etc., and are suitable for aerospace, electronics and other fields that require strict material properties.
Furthermore, in the dye industry, 1-methyl-2-trifluoromethyl-benzene can provide a key structural unit for the synthesis of new dyes. Through rational molecular design and chemical reaction, dyes with bright colors and excellent fastness can be prepared to meet the needs of textile, printing and other industries.
Overall, although 1-methyl-2-trifluoromethyl-benzene is an organic compound, it plays an important role in many fields such as chemical industry, medicine, materials, dyes, etc. It is of great significance to promote technological progress and product innovation in various industries.
What are the physical properties of 1-Methyl-2-Trifluoromethyl-Benzene?
1-Methyl-2-trifluoromethylbenzene is a kind of organic compound. It has unique physical properties and is widely used in chemical industry and other fields.
Looking at its properties, under room temperature and pressure, it is mostly a colorless and transparent liquid, like a clear spring, which may be slightly shiny in the sun. Its smell is similar to fragrant aromatic hydrocarbons, but it also has its own unique smell, which seems to hide a different charm in the elegance.
When it comes to the boiling point, it is about 139-141 ° C. When the temperature gradually rises, it is like a gorgeous transformation, and the liquid turns into a gas state like a spirit, curling and rising. The melting point is about -61 ° C. At such a low temperature, it is like a smart thing is frozen, from liquid to solid, showing a different attitude.
The density of this compound is about 1.17g/cm ³, which is slightly heavier than water. If it is placed in one place with water, it is like a stable person living under a light thing. Its solubility is also unique. It can be well miscible in organic solvents, such as ethanol, ether, etc., just like fish and water, but in water, the solubility is extremely low, as if the two are well-defined and difficult to blend.
In addition, physical properties such as vapor pressure and flash point of 1-methyl-2-trifluoromethylbenzene also have a significant impact on its storage, transportation and use. Vapor pressure reflects the difficulty of evaporation at a certain temperature, while flash point is related to the risk of flammability when exposed to ignition sources such as open flames. Both of these characteristics are key factors that need to be carefully considered in practical applications. They are related to safety and efficiency and cannot be ignored.
What is the chemistry of 1-Methyl-2-Trifluoromethyl-Benzene?
1-Methyl-2-trifluoromethylbenzene, this is an organic compound with unique chemical properties. Its physical properties are colorless liquid with aromatic odor. It has good solubility in organic solvents such as ethanol and ether, but little solubility in water.
From the perspective of chemical activity, the benzene ring imparts aromaticity to the molecular structure, showing typical aromatic compound reaction characteristics. Methyl and trifluoromethyl as substituents have a significant impact on the electron cloud distribution of the benzene ring, thus affecting its reactivity and selectivity.
Trifluoromethyl is a strong electron-absorbing group, which can reduce the electron cloud density of the benzene ring and weaken the electrophilic substitution reactivity of the benzene ring. Compared with benzene, when 1-methyl-2-trifluoromethyl benzene undergoes electrophilic substitution reaction, the reaction conditions are often more harsh, and the substitution check point tends to be relatively high in the electron cloud density. For example, in the halogenation reaction, due to the electron-withdrawing effect of trifluoromethyl, halogen atoms are more likely to replace methyl o and para-hydrogen atoms, and the proportion of para-substitution products may be relatively high, because the steric steric resistance and electronic effect work together.
methyl is the power supply group, which can increase the electron cloud density of the benzene ring to a certain extent. However, the electron-withdrawing effect of trifluoromethyl is more powerful, and the electrophilic substitution activity of the compound is still lower than that of benzene as a whole.
In addition, the carbon-fluorine bond in 1-methyl-2-trifluoromethylbenzene is quite stable, the electronegativity of fluorine atoms is large, and the polarity of carbon-fluorine bonds is strong. Under certain conditions, reactions involving carbon-fluorine bond cleavage can occur. For example, under the action of strong nucleophiles or high temperatures and catalysts, fluorine atoms can be replaced by other groups. However, such reactions usually require specific reaction conditions and catalyst assistance.
In terms of oxidation reactions, due to the presence of methyl groups, methyl groups can be oxidized to carboxyl groups under the action of suitable oxidants such as potassium permanganate to generate 2-trifluoromethylbenzoic acid.
1-methyl-2-trifluoromethylbenzene has unique chemical properties and is often used as an intermediate in the field of organic synthesis. It builds complex organic molecular structures through various reactions and is an important raw material for organic chemistry research and chemical production.
What is 1-Methyl-2-Trifluoromethyl-Benzene production method?
1-Methyl-2-trifluoromethylbenzene, although the preparation method is not detailed in past books, it can be deduced according to various chemical principles.
First, it can be started from a derivative of benzene. First, toluene is used as a base, and by halogenation, the benzene ring is introduced into a halogen atom to obtain o-halotoluene. The halogen atom is quite active, and it can be replaced by a reagent containing trifluoromethyl by a technique of nucleophilic substitution. This reagent containing trifluoromethyl, or Grignard reagent such as trifluoromethyl halide, under suitable reaction conditions, such as in an ether solvent, low temperature and anhydrous environment, the halogen atom is exchanged with the trifluoromethyl group, and then 1-methyl-2-trifluoromethylbenzene is obtained.
Second, aryl borate esters and halogenated compounds containing trifluoromethyl groups can also be used as raw materials. Aryl borate esters can be prepared by metal catalytic coupling of corresponding aryl halides. This aryl borate is reacted with trifluoromethyl halides under the action of a metal catalyst such as palladium, supplemented by a base agent, at a suitable temperature. The alkali agent can adjust the pH of the reaction system, so that the reaction proceeds in the direction of generating the target product. Through this step, 1-methyl-2-trifluoromethylbenzene is also expected to be obtained.
Furthermore, benzene, halomethane and trifluoromethyl halide are used as raw materials, with the help of the principle of Fu-gram alkylation reaction. First, benzene and halomethane are alkylated under the catalysis of Lewis acid catalyst such as aluminum trichloride to obtain toluene. Then toluene and trifluoromethylhalide are substituted under a similar catalytic system, so that trifluoromethylbenzene is introduced into the ortho-position of the benzene ring, and finally 1-methyl-2-trifluoromethylbenzene is obtained. However, the Fu-Ke reaction needs to pay attention to the control of the reaction conditions. Due to the high activity of benzene ring, it is easy to cause side reactions such as multiple substitution.
All preparation methods have their own advantages and disadvantages, and all need to be carefully selected in actual operation according to the availability of raw materials, cost, difficulty of reaction conditions and other factors.
1-Methyl-2-Trifluoromethyl-Benzene what are the precautions during use
1-Methyl-2-trifluoromethylbenzene, this is an organic compound. During use, all precautions are crucial, related to safety and effectiveness, and should not be ignored.
First safety protection. This compound may be toxic and irritating. Be sure to wear protective clothing, carefully selected protective gloves, and wear goggles when operating. Because it may cause damage to the skin, eyes, and respiratory tract, if you accidentally touch the skin, you should immediately rinse with plenty of water. If you feel unwell, seek medical treatment immediately; if you splash into the eyes, you need to quickly rinse with a lot of flowing water, and then rush to the medical office.
Furthermore, ventilation conditions are indispensable. It is suitable for operation in a well-ventilated environment, and it is best to place it in a fume hood. Because of its volatile steam or air pollution, it threatens human health. Good ventilation can disperse the steam in time, reduce the concentration in the air, and ensure the safety of operators.
Fire and explosion protection should not be ignored. 1-methyl-2-trifluoromethylbenzene is flammable. Fireworks should be strictly prohibited in the operation site, and it should be kept away from fire sources, heat sources and strong oxidants. Electrical equipment must be explosion-proof to prevent fire or explosion accidents caused by electrical sparks.
Storage should be sealed and stored in a cool, dry and ventilated place. Keep away from fire and heat sources and prevent direct sunlight. It should be stored separately from oxidants and edible chemicals, and should not be mixed to avoid chemical reactions and safety accidents.
Actions must be precise and standardized in the access and operation links. When measuring, choose appropriate measuring tools to ensure accurate dosage. When transferring and mixing, be careful to avoid spilling and leakage. If there is a leak, personnel from the leaking contaminated area should be quickly evacuated to a safe area, and isolated to strictly restrict access. Emergency personnel must wear self-contained positive pressure breathing apparatus and anti-toxic clothing. Cut off the source of leakage as much as possible to prevent it from flowing into restricted spaces such as sewers and flood drains. Small leakage: mix with sand, dry lime or soda ash. It can also be washed with an emulsion made of non-flammable dispersant, and the lotion is diluted and placed into the wastewater system. Large number of leaks: build a dike or dig a pit to contain. Cover with foam to reduce vapor hazards. Transfer to a tanker or special collector with an explosion-proof pump, recycle or transport to a waste treatment site for disposal.
In addition, its physical and chemical properties should be well understood, such as melting point, boiling point, density, solubility, etc. This will help to optimize the operation process, avoid latent risks, and make the operation safe and secure, and achieve the desired effect. Only by paying careful attention to the above can 1-methyl-2-trifluoromethylbenzene be used safely and effectively.