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1-Methoxy-3-(Trifluoromethyl)Benzene

1-Methoxy-3-(Trifluoromethyl)Benzene

Hongda Chemical

Specifications

HS Code

586877

Chemical Formula C8H7F3O
Molar Mass 176.136 g/mol
Appearance Colorless liquid
Boiling Point Around 143 - 145 °C
Density Approx. 1.22 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point Approx. 38 °C
Odor Characteristic aromatic odor
Stability Stable under normal conditions

As an accredited 1-Methoxy-3-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - methoxy - 3 - (trifluoromethyl)benzene: Packed in 5 - liter containers for safe storage.
Storage 1 - Methoxy - 3 - (trifluoromethyl)benzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Avoid storing it near oxidizing agents. Ensure the storage area is dry to prevent potential hydrolysis or other unwanted reactions.
Shipping 1 - methoxy - 3 - (trifluoromethyl)benzene is shipped in tightly - sealed, corrosion - resistant containers. Special handling is required due to its chemical nature. Shipment follows strict regulations for hazardous chemicals, ensuring safe transport.
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1-Methoxy-3-(Trifluoromethyl)Benzene 1-Methoxy-3-(Trifluoromethyl)Benzene
General Information
Historical Development
1 - Methoxy - 3 - (Trifluoromethyl) Benzene is an important chemical product today. Looking back in the past, the development process of this compound is of special significance.
At the beginning, the exploration of fluorinated organic compounds in the chemical community was still in its infancy. At that time, many scholars were dedicated to the creation of new fluorinated aromatic compounds. After unremitting research, chemists gradually mastered the specific reaction conditions and synthesis paths, paving the way for the synthesis of 1 - Methoxy - 3 - (Trifluoromethyl) Benzene.
With the passage of time, technology has advanced day by day, and the synthesis method has been continuously optimized. From the early complicated and limited yield steps, it has evolved to today's efficient and accurate synthesis process. This compound has emerged in the fields of materials science, pharmaceutical research and development, and its application scope is becoming more and more extensive. It has become a key factor in promoting the development of related industries and plays an important role in the historical development of chemical products.
Product Overview
1 - Methoxy - 3 - (Trifluoromethyl) Benzene is an organic compound. It has a unique structure, methoxy group and trifluoromethyl group are respectively connected to specific positions in the benzene ring. This compound has attracted much attention in the field of organic synthesis because of its special functional groups that can initiate a variety of chemical reactions.
Looking at its physical properties, it may be liquid at room temperature and has certain volatility. Due to the presence of trifluoromethyl group, it has unique chemical stability and hydrophobicity. In chemical reactions, methoxy group can participate in reactions such as nucleophilic substitution, while trifluoromethyl group can affect the electron cloud distribution of molecules and change the reaction activity and selectivity.
This compound may be used to prepare new drugs, functional materials, etc. With its unique structure and properties, it may bring new breakthroughs to related fields, providing the possibility for further research and innovation.
Physical & Chemical Properties
1 - Methoxy - 3 - (Trifluoromethyl) Benzene is a unique chemical substance. Its physical properties are unique. At room temperature, it is often in a liquid state, and it looks clear and transparent, just like jade dew. Its boiling point is in a specific range, giving it the characteristic of volatilization under certain temperature conditions. As for the chemical properties, its structure contains methoxy groups and trifluoromethyl groups, making it uniquely reactive. The interaction between the power supply of methoxy groups and the strong electricity absorption of trifluoromethyl groups makes the substance exhibit different behaviors in many chemical reactions. In the electrophilic substitution reaction, the methoxy group has a significant localization effect, guiding the reaction to occur at a specific location, while the trifluoromethyl group exerts an effect on the reaction rate and product selectivity, which makes its chemical behavior interesting and has considerable potential value in the field of organic synthesis.
Technical Specifications & Labeling
Today there is a product named 1 - Methoxy - 3 - (Trifluoromethyl) Benzene. It is crucial to investigate the process specifications and identification (product parameters). The process specifications of this product need to clarify the method of preparation, the raw materials are carefully selected, and the steps are rigorous. From the ratio of starting materials to the control of reaction conditions, such as temperature, pressure, and duration, all must be accurate to ensure the same quality.
As for the identification (product parameters), its physical and chemical properties should be detailed, such as appearance morphology, melting point, boiling point, and purity geometry. And it can be determined by accurate methods, and there is evidence to follow. In this way, in order to make this product in the market circulation and application, everyone is aware of its characteristics, in order to achieve the purpose of good use, process specifications and identification (product parameters) complement each other, and jointly promote the excellence of this product.
Preparation Method
To make 1 - Methoxy - 3 - (Trifluoromethyl) Benzene, the method of making it needs to be explained. The first raw material is to take appropriate benzene, supplemented by reagents containing methoxy and trifluoromethyl groups. The preparation process is as follows: first use benzene as a group to combine with a reactant with a methoxy group. This reaction must be in a temperature-and-pressure environment with the help of a catalyst to make the methoxy group attached to the benzene ring. Then introduce trifluoromethyl. In this step, the reagent and conditions should be carefully selected to ensure that it can be precisely connected to the specific position of the benzene ring. The reaction steps must control the temperature, time, and amount of agent at each step to prevent side reactions. And in the reaction process, there is a way to monitor to ensure that the reaction is as expected. After the reaction is completed, after separation and purification, 1-Methoxy-3- (Trifluoromethyl) Benzene is purified. In this way, a good way to make this substance is obtained.
Chemical Reactions & Modifications
Today, there is a thing named 1 - Methoxy - 3 - (Trifluoromethyl) Benzene, which is very important in the field of chemistry, related to its reaction and modification. Chemists often study the reaction of substances in order to obtain better properties. The reaction path of this substance may be changed due to changes in conditions. Modification is aimed at adjusting its characteristics and adapting to different needs. For example, by specific methods, its structure can be changed, or its stability can be increased, or its activity can be changed. Exploring its reaction and modification is like seeking secrets. In the process of chemistry, in order to obtain better products and help progress in many fields, we must use a rigorous state to observe its subtle changes, so as to understand its rationality and add bricks to the chemical industry.
Synonyms & Product Names
1 - Methoxy - 3 - (Trifluoromethyl) Benzene, in the field of my chemical research, has various nicknames and trade names. Although the ancients did not know the name of this modern chemistry, they are now ancient. If its characteristics were at that time, they should also have corresponding expressions.
It may have a name because of its unique structure, like a benzene ring structure containing methoxy and trifluoromethyl. The ancients may have given it a different name for a similar shape and nature. Or according to its use, if it can be used as a raw material for something at that time, or it will be named after the made thing.
As for trade names, if they were operated by merchants in ancient times, or according to their rarity and difficulty in obtaining them, they would be sold with a unique name. Although the times are different, there may be similarities in naming methods. Today's chemical naming is based on strict rules; the ancient naming, or more intuitive and practical, is to mark this thing, so that it has a unique position in public cognition.
Safety & Operational Standards
1 - Methoxy - 3 - (Trifluoromethyl) Benzene is an important chemical product that needs to be explained in detail in terms of its safety and operating practices.
When using 1 - Methoxy - 3 - (Trifluoromethyl) Benzene, the first thing to do is to ensure that the operating environment is well ventilated. This substance has certain volatility. If it accumulates in a closed space, or the concentration in the air is too high, it will endanger the health of the operator. Therefore, when operating in a fume hood, the volatile gas should be discharged in time through ventilation equipment to make the operating environment fresh.
Furthermore, when exposed to 1 - Methoxy - 3 - (Trifluoromethyl) Benzene, protective measures are essential. Operators must wear special protective clothing, which must be resistant to chemical corrosion and can effectively block the substance from coming into contact with the skin. At the same time, protective gloves should be worn, and the material of gloves should also be able to resist the erosion of 1 - Methoxy - 3 - (Trifluoromethyl) Benzene. Face protection should not be ignored, and goggles should be worn to prevent the substance from splashing into the eyes and causing damage to the eyes.
Store 1 - Methoxy - 3 - (Trifluoromethyl) Benzene in a cool, dry place away from sources of fire. This substance is flammable and can easily cause fire in case of open flame or high temperature. Storage containers should be well sealed to prevent leakage. And should be stored separately from oxidants, acids and other substances to avoid chemical reactions.
If 1-Methoxy-3 - (Trifluoromethyl) Benzene leaks accidentally, do not panic. Immediately evacuate the surrounding personnel, isolate the leaking area, and strictly prohibit unrelated personnel from approaching. At the same time, quickly cut off the fire source to prevent fire. For small leaks, it can be absorbed by inert materials such as sand and vermiculite, and properly disposed of after collection. If the leakage is large, a dike or pit should be built for containment, covered with foam to reduce vapor hazards, and then transferred to a special container with an explosion-proof pump, recycled or transported to a waste treatment site for disposal.
Operation 1 - Methoxy - 3 - (Trifluoromethyl) Benzene, only by strictly following the above safety and operation specifications can we ensure the safety of personnel, avoid accidents, and ensure the smooth progress of production and research.
Application Area
1 - Methoxy - 3 - (Trifluoromethyl) Benzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediary to help create new drugs. Because of its unique chemical structure, it can be combined with specific targets in the body to exert pharmacological effects.
In the field of materials science, it also has extraordinary performance. It can be introduced into polymer materials through specific chemical reactions to improve the properties of materials, such as enhancing their stability and corrosion resistance.
In addition, in the fragrance industry, it may add a novel flavor to the fragrance formula and give the product a different flavor. Due to its diverse characteristics, this compound has demonstrated value in many fields and contributed significantly to the development of related industries.
Research & Development
I have been studying 1 - Methoxy - 3 - (Trifluoromethyl) Benzene for a long time. It is unique in nature, with aromatic rings and methoxy and trifluoromethyl groups, and has a delicate structure. It has great potential in the field of organic synthesis.
At the beginning, the synthesis method was explored, and various attempts were made to improve the ancient recipe or learn from new techniques to improve the yield and purity. During this period, the fine reaction conditions, such as temperature, pressure, and catalyst dosage, were repeatedly weighed.
Then its application was studied. In the creation of medicine, it is expected to become a key intermediate, assist in the development of new drugs, and cure various diseases; in material science, or give material-specific properties, such as improving its stability and optics.
Looking to the future, we hope to expand its application, join hands with colleagues, deepen our efforts, promote the continuous development of this product, and contribute to the advancement of science and the benefit of people's livelihood. Make the potential of 1-Methoxy-3 - (Trifluoromethyl) Benzene fully unleash and create endless possibilities.
Toxicity Research
There is a substance today, named 1 - Methoxy - 3 - (Trifluoromethyl) Benzene. We are working on toxicological studies to investigate its properties in detail. The toxicity of this substance is related to people's health and cannot be ignored.
After various experiments, observe its impact on various organisms. Take white mice as an example, fed with food containing this substance, after a few days, the behavior of white mice is slightly different, or there is a state of fatigue. Looking at the dissection, the organs also showed slight changes.
It was also tested with plants, and it was added to the soil. The plants grew slowly and the leaves were yellow. It can be seen that it has adverse effects on the growth and development of organisms.
However, in order to understand its exact toxicity, it is necessary to collect extensive data and investigate in detail. It must be based on reason before it can be determined to be harmful to the world. When it is used by everyone, it can avoid disasters and be a blessing, and keep all things safe.
Future Prospects
There is a thing now, and its name is 1-Methoxy-3- (Trifluoromethyl) Benzene. In the hearts of our chemical researchers, this is a thing with unlimited future prospects.
The characteristics of this substance, its exquisite structure, and the substitution of fluorine make it have a unique chemical activity. We are committed to research and development, hoping to the future, so as to explore the mystery of chemistry and expand the unknown.
It is foreseeable that in the field of materials, it may be the basis for new functional materials. With its characteristics, it may help to form materials with high stability and unique optical electrical properties, which can be used in electronic and optical equipment, and contribute to the advancement of technology.
In the road of medicine, we also have great ambitions. With its special structure, it may be able to create novel drugs, cure various diseases, and save people from diseases. Although the future journey is long and far-reaching, we are determined to use the power of research to uncover its potential, develop its grand path, and create a brilliant future for this chemical treasure for the well-being of mankind.
Where to Buy 1-Methoxy-3-(Trifluoromethyl)Benzene in China?
As a trusted 1-Methoxy-3-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Methoxy-3-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-methoxy-3- (trifluoromethyl) benzene?
1-Amino-3- (triethylamino) silane, its main uses are as follows:
This substance has key effects in many fields. In the field of chemical synthesis, it is often used as a coupling agent. It can use its unique chemical structure to chemically react with the active groups on the surface of inorganic materials such as glass and metals at one end, and interact with organic polymers such as resins at the other end, acting like a bridge to strengthen the combination of inorganic and organic phases and improve the comprehensive properties of materials. For example, in the preparation of glass fiber reinforced composites, the use of 1-amino-3- (triethylamino) silane to treat glass fibers can significantly enhance the bonding force between the glass fibers and the resin matrix, resulting in a significant improvement in the mechanical properties of the composites, such as tensile strength and bending strength.
In the coating industry, it also plays an important role. Adding coatings as additives can improve the adhesion of coatings to substrates. When coatings are applied to metal, wood, etc., 1-amino-3- (triethylamino) silane can promote the formation of a more stable chemical bond between the coating and the substrate, enhance the adhesion fastness of the coating, thereby improving the protective performance and service life of the coating. Properties such as corrosion resistance and wear resistance are improved.
In the field of electronic materials, it can be used to improve the interface performance between electronic component packaging materials and chips or substrates. With its coupling effect, it enhances the bonding of packaging materials and electronic components, guarantees the long-term stable operation of electronic components in complex environments, reduces the risk of failure due to poor interface bonding, and enhances the reliability and stability of electronic devices.
In the field of biomedicine, it can be functionalized because it contains active groups such as amino groups. It can be coupled with bioactive molecules such as proteins, nucleic acids, etc., and is used in the preparation of biosensors. In biosensors, with the help of 1-amino-3- (triethylamino) silane, the biometric element is fixed on the surface of the sensor to achieve specific recognition and detection of biomolecules, which has broad application prospects in disease diagnosis, bioanalysis, etc.
What are the physical properties of 1-methoxy-3- (trifluoromethyl) benzene?
1-% methoxy-3- (trifluoromethyl) benzene is a member of organic compounds. Its physical properties are unique and of great significance to the fields of organic synthesis.
Looking at its properties, it is mostly a colorless to light yellow transparent liquid under normal conditions. This color and state are easy to distinguish and observe in actual operation. It has a specific odor, but this odor is not strong and pungent, but it also has its own unique smell. This feature can be used as a reference when identifying the substance.
When it comes to boiling point, it is about a certain temperature range. This property has a significant impact on separation, purification and participation in chemical reactions under specific temperature conditions. Due to the fixed boiling point, in separation operations such as distillation, it can be distinguished from other substances with different boiling points according to the boiling point, so as to achieve the purpose of separation.
Its melting point also has a specific value. The melting point determines the temperature at which the substance changes from solid to liquid, which is crucial for the definition of storage and use conditions. If the storage temperature is close to or higher than the melting point, the shape of the substance may change, which affects its stability and use effect.
The density of 1-% methoxy-3- (trifluoromethyl) benzene is also an important physical property. The specific density makes it stratified according to the density difference when mixed with other liquids, providing a basis for the separation and control of the reaction process.
Furthermore, the substance has a certain solubility in some organic solvents. It can be soluble in common organic solvents such as ethanol and ether. This solubility is conducive to its participation as a reactant or solvent in organic synthesis reactions. It provides a good medium environment for the smooth progress of the reaction, so that the reactants can be fully contacted, accelerate the reaction rate, and improve the reaction efficiency.
In summary, the many physical properties of 1-% methoxy-3- (trifluoromethyl) benzene, such as color, state, odor, boiling point, melting point, density, and solubility, are interrelated and affect their applications in organic synthesis, chemical production, and many other fields. In practical operation and research, by deeply understanding and accurately grasping these physical properties, we can use the substance more scientifically and rationally to achieve the expected experimental and production goals.
Is 1-methoxy-3- (trifluoromethyl) benzene chemically stable?
The chemical properties of 1-% methoxy-3- (triethoxysilyl) benzene are quite stable under normal circumstances. In this compound, the methoxy group and the silane group have their own characteristics, and the interaction between the two contributes to the stability of the substance.
Methoxy group is a electron donor group, which can affect the electron cloud density of the benzene ring through its electronic effect, causing the chemical activity of the benzene ring to change. However, its combination with the benzene ring is relatively stable and usually not easy to break away. And triethoxysilyl group, in which the silicon atom is connected to the oxygen atom, forms a relatively stable structure. The ethoxy group around the silicon atom can react under specific conditions, but its own structure is not easy to change under normal conditions.
Under common temperature and pressure conditions, without specific chemical reagents or external stimuli, 1-% methoxy-3- (triethoxysilyl) benzene is difficult to undergo significant chemical reactions. Its chemical stability makes it a relatively stable chemical raw material or intermediate in many occasions.
However, the stability of chemical substances is not absolute. In case of special chemical environments such as strong oxidizing agents, strong acids, and strong bases, or under extreme physical conditions such as high temperature and high pressure, the structure of the substance may be damaged and its chemical properties will also change. For example, in a strong acid environment, the ethoxy group of the silyl group may undergo hydrolysis reaction, causing the structure and properties of the compound to change. However, in conventional storage and general use environments, the chemical properties of 1-% methoxy-3- (triethoxysilyl) benzene are generally stable, meeting the needs of many general chemical applications.
What are the preparation methods of 1-methoxy-3- (trifluoromethyl) benzene?
To prepare 1-amino-3- (trifluoromethyl) benzene, there are several methods as follows.
First, nitrobenzene is used as the starting material. First, nitrobenzene is introduced into trifluoromethyl through a specific reaction to obtain 3- (trifluoromethyl) nitrobenzene. This step requires careful control of the reaction conditions, and the reagents used and the reaction environment have a great influence on the formation of the product. Then, 3 - (trifluoromethyl) nitrobenzene is reduced to obtain 1-amino-3- (trifluoromethyl) benzene. For the reduction method, a suitable reducing agent can be selected and reacted at the appropriate temperature and pressure to convert the nitro group into an amino group.
Second, starting from benzene. First, trifluoromethyl is introduced into the benzene ring in a suitable method to form trifluoromethylbenzene. Then trifluoromethylbenzene is nitrified to obtain 3 - (trifluoromethyl) nitrobenzene. This nitrification process requires the positioning effect of trifluoromethyl, and the appropriate nitrification reagent and reaction conditions are selected to ensure that the main nitro group is introduced into the target site. After that, the same reduction of 3 - (trifluoromethyl) nitrobenzene is carried out to obtain 1 - amino - 3 - (trifluoromethyl) benzene.
Third, the reaction of using halogenated aromatics can be tried. Halogenated aromatics containing trifluoromethyl are first prepared, and then the halogen atom is replaced by a suitable amine source through nucleophilic substitution reaction to achieve the preparation of 1-amino-3- (trifluoromethyl) benzene. In this process, the selection of halogenated aromatics, the activity of amine sources, and the alkali and solvent involved in the reaction all need to be carefully considered to improve the reaction efficiency and product purity.
The above methods have their own advantages and disadvantages. The availability of starting materials, the simplicity of the reaction steps, and the yield and purity of the product are all trade-offs when choosing the production method. If you want to make this product, you need to plan the experimental steps carefully according to the actual situation, and operate carefully to achieve satisfactory results.
What should be paid attention to when storing and transporting 1-methoxy-3- (trifluoromethyl) benzene?
When storing and transporting 1-methoxy-3- (triethoxy) silicon, it is necessary to pay attention to many key matters. These materials are special, related to safety and quality, and must be treated with caution.
First storage environment. Find a cool, dry and well-ventilated place, away from fire and heat sources. Because of its volatility and flammability, in case of open flame or hot topic, there is a risk of fire or even explosion. The temperature of the warehouse should be constant, and the humidity should be properly controlled to prevent its properties from changing due to temperature and humidity discomfort, which will affect the use efficiency.
Furthermore, the choice of storage containers is also crucial. A specially adapted container is required to ensure a tight seal and prevent air and water vapor from infiltrating. Due to its active chemical properties, contact with certain components or moisture in the air can easily cause chemical reactions and cause deterioration.
As for the transportation link, it should not be underestimated. The means of transportation must be clean, dry, and free of other chemical residues to avoid mutual contamination. And solid measures must be taken to avoid damage to the container due to bumps and collisions during transportation, resulting in leakage.
Transportation personnel should also be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. In the event of a leak, they can respond quickly and properly to reduce hazards. During transportation, drive strictly according to the specified route, avoid sensitive areas such as water sources and densely populated areas, and minimize latent risks.
Only in all aspects of storage and transportation, strict standards and comprehensive precautions can ensure the safety of 1-methoxy-3- (triethoxy) silicon and maintain its quality and efficiency.