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What are the chemical properties of 1-Isothiocyanato-4- [ (Trifluoromethyl) Sulfanyl] Benzene
1-Isothiocyanate-4- [ (trifluoromethyl) thioalkyl] benzene, this is an organic compound. Its chemical properties are quite unique, and the isothiocyanate and (trifluoromethyl) thioalkyl groups contained in its structure are also unique.
isothiocyanate has high reactivity and can often undergo nucleophilic addition reactions with compounds containing active hydrogen, such as alcohols and amines. When it encounters alcohols, it can form corresponding thiocarbamates; when it encounters amines, it can form thiourea derivatives. This reactivity provides an important path for the construction of new sulfur-containing nitrogen-containing compounds in organic synthesis.
And (trifluoromethyl) thioalkyl, due to the strong electron absorption of trifluoromethyl, endows the compound with special electronic effects and fat solubility. Strong electron absorption can affect the electron cloud density distribution on the benzene ring, thereby changing the activity and selectivity of benzene ring-related reactions. In many chemical reactions, it can guide the reaction in a specific direction. And because of its lipid solubility, this compound may have potential applications in the field of biological activity research and pharmaceutical chemistry, because it can help it more easily penetrate biofilms and enhance bioavailability.
In addition, the benzene ring structure in this compound is relatively stable, providing a certain rigid framework for the entire molecule. However, it can also participate in typical reactions of benzene rings, such as electrophilic substitution reactions, but due to the presence of isothiocyanate and (trifluoromethyl) thioalkyl groups, the reaction check point and activity will be different from simple benzene derivatives.
In summary, the chemical properties of 1-isothiocyanate-4- [ (trifluoromethyl) thioalkyl] benzene are synergistically formed by the structure of its parts, and show potential important value in organic synthesis, drug development and other fields.
What are the main uses of 1-Isothiocyanato-4- [ (Trifluoromethyl) Sulfanyl] Benzene
1-Isothiocyanate-4- [ (trifluoromethyl) thio] benzene has a wide range of uses and is used in the fields of chemical industry and medicine.
In the chemical industry, it can be a key raw material for the synthesis of special materials. Based on this substance, a polymer with special properties can be prepared. Because of its special structure containing isothiocyanate group and trifluoromethyl thio group, the polymer has excellent chemical stability, weather resistance and electrical properties. The resulting material can be used for insulating components of high-end electronic equipment, and can also maintain stable performance in harsh environments, so that the equipment can operate stably.
In the field of medicine, its role is also crucial. It can act as an intermediary for drug synthesis, with its special chemical structure, it can be linked with many bioactive molecules to obtain new drugs with specific pharmacological activities. Or in the creation of anti-cancer drugs, it is cleverly designed to target specific cancer cells, and its special structure is compatible with the surface receptors of cancer cells to precisely attack cancer cells, while minimizing damage to normal cells, providing a new way to overcome cancer problems.
Or in the development of new antimicrobial drugs, with its unique chemical properties, it interferes with the metabolic pathway of bacteria, destroys the cell wall and cell membrane structure of bacteria, and achieves antibacterial effect. In order to deal with the increasingly serious problem of bacterial resistance, it adds a powerful method.
In short, 1-isothiocyanate-4- [ (trifluoromethyl) thio] benzene has broad prospects in the chemical and pharmaceutical fields, paving the way for many innovative research and practical applications.
What is the preparation method of 1-Isothiocyanato-4- [ (Trifluoromethyl) Sulfanyl] Benzene
The preparation method of 1-isothiocyanate-4- [ (trifluoromethyl) thioalkyl] benzene is a key issue in the field of organic synthesis. To prepare this substance, the following route is often followed.
First, start with a sulfur-containing reagent and a fluorine-containing reagent. Choose a suitable mercaptan derivative, and the mercaptan needs to be able to undergo nucleophilic substitution reaction with trifluoromethyl. Here, a mercaptan with an active sulfur atom can be found, which reacts with a trifluoromethylating reagent under specific conditions to form an intermediate containing (trifluoromethyl) thioalkyl. This reaction requires fine regulation of reaction temperature, reaction time and ratio of reactants. If the temperature is too high, or side reactions occur frequently, the product is impure; if the temperature is too low, the reaction rate will be slow and it will take too long. Generally speaking, the reaction temperature should be controlled in a suitable range, such as low temperature to medium temperature range, or the duration may take several days or even several days, depending on the specific reaction system.
Second, the resulting intermediate containing (trifluoromethyl) thioalkyl group is introduced into isothiocyanate. This step can be achieved by the reaction with thiocyanate. Choose a thiocyanate with moderate activity, such as alkali metal thiocyanate, and mix it with the intermediate in a suitable solvent. The choice of solvent is very critical, and it is necessary to be able to dissolve the reactants without interfering with the reaction process. Organic solvents such as acetonitrile and dichloromethane may be good choices. In this process, it is necessary to pay attention to the pH value of the reaction, because pH affects the reaction rate and product configuration. Maintaining an appropriate pH allows the reaction to proceed smoothly in the direction of generating the target product 1-isothiocyanate-4- [ (trifluoromethyl) thioalkyl] benzene. At the same time, the reaction process may need to be catalyzed to accelerate the reaction process and increase the yield.
Preparation of 1-isothiocyanate-4- [ (trifluoromethyl) thioalkyl] benzene requires careful planning of each step of the reaction and strict control of the reaction conditions, so that high purity and yield products can be obtained.
1-Isothiocyanato-4- [ (Trifluoromethyl) Sulfanyl] Benzene What are the precautions in storage and transportation
1-Isothiocyanate-4- [ (trifluoromethyl) thioalkyl] benzene, there are a number of urgent precautions to be paid attention to during storage and transportation.
The first to bear the brunt is the control of temperature. The properties of this substance may be affected by changes in temperature, so when stored in a cool place, it must not be exposed to high temperature or direct sunlight. High temperature can easily cause its chemical properties to be unstable, or cause decomposition and deterioration, which can damage its quality and utility.
Furthermore, the consideration of humidity should not be underestimated. Humid environment may affect the purity and reactivity of the substance. Therefore, the storage place must be kept dry and a desiccant can be prepared to prevent moisture from invading.
When it comes to transportation, the stability of the packaging is crucial. Appropriate packaging materials need to be selected to ensure that it will not be damaged and leaked during the bumpy transit. The packaging needs to be well sealed to prevent contact with outside air, moisture, etc.
In addition, this substance may be toxic and irritating to a certain extent. Those who operate and transport it must take protective measures. Wear protective clothing, gloves and goggles to prevent inadvertent contact and injury to the body.
At the same time, the transportation and storage place should be kept away from fire sources, heat sources and all kinds of flammable and explosive materials. Due to its chemical properties, in the event of an open flame or hot topic, there may be a risk of combustion or explosion.
And during storage and transportation, it is necessary to have clear labels indicating its characteristics, hazards and emergency treatment methods. In the event of an accident, relevant personnel can take prompt and correct response measures according to the signs to reduce losses and hazards. In this way, the safety and stability of 1-isothiocyanate-4 - [ (trifluoromethyl) thialkyl] benzene during storage and transportation must be ensured.
What is the approximate market price of 1-Isothiocyanato-4- [ (Trifluoromethyl) Sulfanyl] Benzene
I don't know where the city of 1-Isothiocyanato-4- [ (Trifluoromethyl) Sulfanyl] Benzene is. This is a chemical product, and its quality is often affected by various factors, such as the quality of the product, the quality of supply and demand, the ease of law, and the quality of the market. If you want to know the market, you need to contact the market for chemical raw materials, the supply of chemical products, or the relevant platform, and you can only get it. Or consult someone who is familiar with the chemical market, or you may be able to get useful information. However, I can't take the market for this compound immediately today, so I will let you know with the help of the relevant information.