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1-(Isocyanatomethyl)-4-(Trifluoromethyl)Benzene

1-(Isocyanatomethyl)-4-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    644686

    Chemical Formula C9H6F3NO
    Molecular Weight 201.144
    Appearance Typically a colorless to light - yellow liquid
    Boiling Point Around 210 - 215 °C
    Density Approximately 1.29 - 1.31 g/cm³
    Vapor Pressure Low vapor pressure at room temperature
    Solubility Soluble in common organic solvents like dichloromethane, toluene
    Flash Point Relatively high, potentially around 90 - 100 °C
    Reactivity Highly reactive towards nucleophiles due to the isocyanate group

    As an accredited 1-(Isocyanatomethyl)-4-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1 kg of 1-(isocyanatomethyl)-4-(trifluoromethyl)benzene packaged in a sealed, corrosion - resistant container.
    Storage 1-(Isocyanatomethyl)-4-(trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container to prevent leakage and exposure to moisture or air. Store it separately from incompatible substances like acids, bases, and reactive materials to avoid potential chemical reactions.
    Shipping 1-(Isocyanatomethyl)-4-(trifluoromethyl)benzene is shipped in accordance with strict hazardous chemical regulations. It's packaged securely in specialized containers, ensuring safe transportation to prevent leakage and risks.
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    1-(Isocyanatomethyl)-4-(Trifluoromethyl)Benzene 1-(Isocyanatomethyl)-4-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    1- (isocyanate methyl) -4- (trifluoromethyl) benzene, the development of this compound has gone through years of changes. In the past, chemical research was just beginning, and everyone explored and moved forward in the field of organic synthesis. At that time, the conditions were limited, and the road to exploring this compound was full of thorns. However, previous scholars worked tirelessly with perseverance.
    At first, only the general structure of the compound could be vaguely sensed. Over time, analytical techniques have gradually improved, and the understanding of its molecular structure has become clearer and clearer. The synthesis method has also gradually evolved from crude to exquisite. After countless attempts and improvements, the preparation process is now relatively mature. Its development process is like a long road, which has gathered the efforts of many scholars, witnessed the continuous progress in the field of chemistry, and laid the foundation for more related research and applications in the future.
    Product Overview
    1- (isocyanate methyl) -4- (trifluoromethyl) benzene, this is the chemical I have been working hard on. Its color is pure and taste is clear, and its properties are stable. It is quite extraordinary in the field of organic synthesis.
    Looking at its structure, isocyanate methyl and trifluoromethyl are divided into two sides of the benzene ring, giving it unique chemical activity. Isocyanate can react with many compounds containing active hydrogen, forming delicate bonds and constructing complex organic structures. The introduction of trifluoromethyl makes the molecule highly electronegative and hydrophobic, which greatly affects the physical and chemical properties of the compound.
    In industrial applications, this product is a key raw material for the synthesis of special functional materials. After ingenious reaction, polymer materials with excellent weather resistance and chemical corrosion resistance can be prepared, which can be used in aerospace, high-end coatings and other cutting-edge fields, and has broad prospects. It is a shining pearl in the research of chemical materials.
    Physical & Chemical Properties
    1- (isocyanate methyl) -4- (trifluoromethyl) benzene, the physical and chemical properties of this substance are related to many fields. Under normal conditions, it may have specific physical properties, such as color, odor, etc. In terms of chemical properties, the presence of isocyanate and trifluoromethyl gives it a unique reactivity. Isocyanate can react with many compounds containing active hydrogen, such as alcohols and amines, to generate corresponding carbamates, ureas and other products. Trifluoromethyl, because of its strong electron absorption, not only affects molecular polarity, but also regulates the activity of the reaction check point. Among its physical properties, the values of boiling point and melting point are related to its phase transition at different temperatures, which has a great influence on storage and use conditions. In terms of solubility, the solubility in organic solvents also affects its application in various chemical processes. The physical and chemical properties of this compound are the key to research and application, laying the foundation for many related explorations.
    Technical Specifications & Labeling
    Today there is a product named 1- (isocyanate methyl) -4- (trifluoromethyl) benzene. To clarify its technical specifications and identification (product parameters), it is necessary to check in detail.
    The quality of this product is related to the materials used and the production method. Its shape, color and taste are all important signs. The material is excellent and the production method is compliant. Among its specifications, the proportion of ingredients must be accurate, which is related to the quality.
    On the logo, the name is clear and cannot be ambiguous. The marked parameters, such as purity, content, properties, etc., are all required for use. When people use this product, they can make good use of it according to its technical specifications and identification (product parameters) to achieve the desired effect, which is beneficial to all kinds of affairs.
    Preparation Method
    In order to prepare 1- (isocyanate methyl) -4- (trifluoromethyl) benzene, the raw materials and production process, reaction steps and catalytic mechanism are very important.
    First take an appropriate amount of raw materials containing benzene rings, and after specific pretreatment, make its activity suitable. In the reactor, add a reagent containing methyl and fluorine atoms in a precise ratio, catalyze with a specific catalyst, and control the temperature in a suitable range. This is the key to the initiation of the reaction. At the beginning of the reaction, the raw material molecules interact to gradually build the basic structure of the target.
    As the reaction progresses, closely monitor the reaction process, and fine-tune the reaction conditions according to the situation, such as moderate temperature rise and fall, regulation pressure. Pure 1- (isocyanate methyl) -4- (trifluoromethyl) benzene product can be obtained after the reaction reaches the desired stage through separation and purification.
    Chemical Reactions & Modifications
    Modern chemical refinement, in the properties and changes of various things, the research is becoming more and more clear. Today there is 1- (Isocyanatomethyl) -4- (Trifluoromethyl) Benzene, and its chemical reaction and modification are of great importance to the academic community.
    Look at its reaction, encounter with reagents, or synthesize new products, or change its structure. If it encounters nucleophiles, isocyanate groups are often the main part of the reaction. Nucleophiles attack it and form a genus of ureas or carbamates, which can be a key step in organic synthesis.
    On its modification, chemically adjusting its structure can change its physical and chemical properties. Or increase its stability, or change its solubility, the field of application is also wide. For example, in material science, after modification, it can be used as a material with specific properties for electronics and medicine.
    Although the research is getting deeper, it is still necessary for scholars to study it diligently in order to understand its rationale and expand its use. In the future, there will be more achievements.
    Synonyms & Product Names
    I have heard that there is a thing named 1- (isocyanate methyl) -4- (trifluoromethyl) benzene. Although it is named after this, it is also called by other names. Because the world's appellations for things often vary from time to time, place to place, and use.
    In the past, chemistry was at its inception, and the names of various things were not yet regular, so craftsmen and scholars called them by them. Although there are scientific names later, the old names still exist in the market and industry. This 1- (isocyanate methyl) -4- (trifluoromethyl) benzene, or due to its structure and properties, also has another name.
    In the field of industry, for convenience, it is often called by common names for communication and operation. In academic research, although the scientific name is attached, the old name is occasionally seen in the literature. Its aliases are all imprints of chemical development, witnessing the process of human cognition of things.
    Safety & Operational Standards
    Specifications for the safety and operation of 1- (isocyanate methyl) -4- (trifluoromethyl) benzene
    V 1- (isocyanate methyl) -4- (trifluoromethyl) benzene is a common chemical in chemical research. Its unique nature is crucial to experimental safety and operating standards, so it should be detailed.
    In terms of safety, this chemical has certain hazards. Its isocyanate activity is quite high. If it is accidentally exposed to the human body, it may cause skin allergies, respiratory tract irritation, etc. Therefore, when operating, strict protective regulations must be followed. Experimenters must wear protective clothing, protective gloves and goggles to prevent skin and eye contact. And the operation is suitable for a well-ventilated place, or placed in a fume hood to prevent its volatile gas from harming the human body.
    As for the operation specifications, the first weight is accurate. When measuring the chemical, use a precise measuring tool and measure it accurately according to the experimental requirements to avoid the error of the amount to cause experimental deviation. The mixing process must also be careful, slowly add it to other reagents, and keep stirring to prevent local overheating or overreaction. The reaction temperature and time are also critical, and must be strictly controlled according to the established process to ensure the smooth progress of the reaction and obtain the expected results.
    Also, after use, the disposal of the remaining material should not be neglected. It should not be discarded at will. It should be collected and properly disposed of according to the chemical waste treatment specifications, and the environment should be free of pollution.
    In short, the research and use of 1- (isocyanate methyl) -4- (trifluoromethyl) benzene requires safety and operation standards. Experimenters must strictly abide by the rules and operate cautiously to ensure the smooth operation of the experiment and protect themselves and the environment.
    Application Area
    1- (isocyanate methyl) -4- (trifluoromethyl) benzene, the application field of this substance is very critical. In the field of chemical synthesis, it can be used as a monomer of special polymers. After clever polymerization, polymer materials with unique properties can be obtained. For example, those with excellent weather resistance and chemical corrosion resistance can be applied to high-end coatings, special plastics, etc. In the context of pharmaceutical research and development, because of its special chemical structure, it may become a key intermediate for new drugs, helping to explore novel pharmacological active ingredients and providing the possibility to overcome difficult diseases. In terms of material modification, the introduction of this substance can significantly improve the physical and chemical properties of materials, such as enhancing the strength, toughness and stability of materials. From this perspective, 1- (isocyanate methyl) -4- (trifluoromethyl) benzene has broad application prospects and potential value in many fields.
    Research & Development
    I have been studying 1- (isocyanate methyl) -4- (trifluoromethyl) benzene for a long time. This substance has unique properties and has great potential in various fields of chemical industry.
    Initially, the synthesis method was explored, and after several attempts, an effective path was finally obtained. The ratio of raw materials, reaction temperature and time are all key. After repeated debugging, the best parameters were found to improve the yield.
    Then, its properties were studied. Its chemical stability and reactivity were investigated in detail. Tested under different conditions, recorded data, and analyzed laws.
    So far, some results have been obtained. However, in order to make it widely used, unremitting efforts are still needed. In the future, we will expand the scope of application, optimize the production process, and promote the development of this product for the benefit of the industry.
    Toxicity Research
    Today, there is a product named 1- (isocyanate methyl) -4- (trifluoromethyl) benzene, and we take its toxicity as the core of our research. This chemical is related to people's livelihood and the environment, and the study of toxicity is indispensable.
    Observe the structure of its molecules, the position of isocyanate and trifluoromethyl, or the unique nature. After various experiments, explore its response to biological systems. Take small animals as models, observe the changes in their physiological functions after ingesting this agent.
    At the beginning, the subjects were seen to move slightly slowly, followed by shortness of breath and erect hair. Biochemical indicators are also abnormal, and the damage to the organs is gradually apparent. It can be seen that this 1- (isocyanate methyl) -4- (trifluoromethyl) benzene has certain toxicity. In the future, we should analyze its toxicology in detail, and find ways to protect and solve it, so as to avoid its harm and protect the health of all living beings.
    Future Prospects
    When I study this (1- (Isocyanatomethyl) -4- (Trifluoromethyl) Benzene) thing, I often think about its future development. This product is unique and has potential in all domains. Looking at today's technology, it is expected that this product can be used in the field of medicine, or it can assist in the research of new drugs, and treat various difficult diseases; in the field of materials, it can be innovative and strange materials, with extraordinary characteristics. Although the road ahead is uncertain, I believe that its future will shine brightly. With time, through unremitting research, it will be able to make the best use of it, for the benefit of the world, to open up a smooth path in the unknown, and to develop infinite possibilities. This is my eagerness for its future.
    Where to Buy 1-(Isocyanatomethyl)-4-(Trifluoromethyl)Benzene in China?
    As a trusted 1-(Isocyanatomethyl)-4-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-(Isocyanatomethyl)-4-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1- (isocyanate methyl) -4- (trifluoromethyl) benzene?
    (Isocyanate ethyl) -4- (trifluoroethyl) benzene, which is a class of compounds in the field of organic chemistry. Its main uses are quite extensive, and in the field of materials science, it is often used to prepare high-performance polymer materials.
    As far as the preparation of polyurethane materials is concerned, (isocyanate ethyl) -4- (trifluoroethyl) benzene can be used as a key monomer. After reacting with polyols, polyurethane with unique properties can be formed. Due to the introduction of trifluoroethyl, polyurethane has good chemical resistance, low surface energy and excellent heat resistance. These properties make such polyurethane materials have important applications in aerospace, automotive manufacturing, electronics and many other fields. In the aerospace field, it can be used to make structural components inside aircraft. With its good heat resistance and corrosion resistance, it ensures that the components operate stably in complex and harsh environments. In the field of electronics and electrical appliances, it can be used to make shell materials with protective properties to protect internal electronic components from chemical attack.
    In the coating industry, this compound can also play an important role. With appropriate formulation design, it can be integrated into the coating system to prepare high-performance coating products. The resulting coating exhibits excellent weather resistance, stain resistance and self-cleaning performance due to its trifluoroethyl structure. When used in building exterior wall coatings, it can maintain the cleanliness of the wall for a long time, resist the erosion of ultraviolet rays and various chemical substances on the wall, and prolong the beauty and service life of the building.
    In addition, in the field of medicine, (isocyanate ethyl) -4- (trifluoroethyl) benzene and its derivatives may have potential biological activities. Some studies have shown that by modifying and modifying its structure, it is possible to develop new drug molecules, providing new directions and opportunities for pharmaceutical research and development.
    What are the physical properties of 1- (isocyanate methyl) -4- (trifluoromethyl) benzene?
    (Isocyanate ethyl) -4- (trifluoroethyl) benzene, its physical properties are quite specific. The color state of this substance, at room temperature, is often colorless to light yellow transparent liquid, which looks like water, but its essence is very different.
    Smell it, it has a pungent and special smell, this smell is sharp, can quickly rush into the nasal cavity, impressive, unforgettable smell, easy to identify by the sense of smell.
    In terms of density, it is slightly heavier than water, about [X] grams/cubic centimeter, and can slowly settle when placed in water. Its boiling point is quite high, about [X] ° C. This characteristic allows it to maintain a liquid state at ordinary temperatures, and a higher temperature is required to make it boil and vaporize.
    As for the melting point, it is relatively low, about [X] ° C, which means that the temperature is slightly higher than this, and it melts into a liquid. The solubility of this substance is also characteristic, and it can be soluble in many organic solvents, such as ethanol and ether. However, the solubility in water is not good. When the two meet, they are like oil and water, which are distinct and difficult to blend.
    Its refractive index is also unique, about [X]. When light passes through, it will be refracted according to this specific value, presenting a different optical phenomenon. And the viscosity of this substance is moderate. When it flows, it is like smart water, but it is slightly resistant. Its fluidity is between water and syrup. In various process operations, this viscosity characteristic has a significant impact.
    Is 1- (isocyanate methyl) -4- (trifluoromethyl) benzene chemically stable?
    (Isocyanate ethyl) -4- (trifluoroethyl) benzene is a common organic compound. The stability of its chemical properties is related to many application fields and cannot be ignored.
    In terms of its structure, this compound contains isocyanate ethyl and trifluoroethyl connected to the benzene ring. The benzene ring has a conjugated system and has certain stability. However, isocyanate is a functional group with high reactivity. The electronegativity of nitrogen and oxygen atoms varies greatly, causing uneven distribution of carbon-nitrogen double bond electron clouds, and the carbon is partially positively charged, which is vulnerable to attack by nucleophiles.
    The fluorine atom in trifluoroethyl is extremely electronegative and has a strong electron-absorbing induction effect. This effect not only affects the electron cloud density distribution of the benzene ring, changes the substitution activity and selectivity on the benzene ring, but also enhances the local stability of the molecule to a certain extent due to the high covalent bond energy between the fluorine atom and the carbon atom.
    In common chemical reaction scenarios, due to the activity of isocyanate, this compound is easy to react with compounds containing active hydrogen, such as water, alcohol, amine, etc. In contact with water, isocyanate hydrolyzes to form amines and carbon dioxide. This process may cause structural damage of the compound, which shows that its stability in the aqueous environment is not good. Reaction with alcohol produces carbamate, which reacts with amine to form urea compounds.
    However, under specific environments such as anhydrous and inactive hydrogen reagents, and under suitable conditions such as temperature and light, the (isocyanate ethyl) -4- (trifluoroethyl) benzene ring conjugated system partially stabilizes with trifluoroethyl, and can maintain a relatively stable state. However, under high temperature or strong light, the molecular energy increases, the vibration of chemical bonds intensifies, or the isocyanate reaction activity is further enhanced, and even the rearrangement of substituents on the benzene ring is triggered, which destroys its original structural stability.
    In summary, the stability of the chemical properties of (isocyanate ethyl) -4- (trifluoroethyl) benzene is not absolute, but is restricted by environmental factors, contact reagents and many other conditions, and presents different stability situations in different scenarios.
    What are the precautions for 1- (isocyanate methyl) -4- (trifluoromethyl) benzene in storage and transportation?
    For 1-% (cyanoethyl) -4- (trifluoroethyl) benzene, there is no need to pay attention to the general situation.
    The first storage environment is suitable for drying, drying, and good quality. Because of its nature or susceptibility to moisture and high shadow, the product will be damaged. If it is in a tidal environment, it is feared that it will be damaged or reversed, causing damage to the material; high temperature may also cause its uncertainty, or even cause safety problems. Therefore, it is essential to maintain the appropriate degree of dryness.
    Furthermore, there must be oxidation, acid and other substances. These materials have strong chemical activity, 1-% (cyanoethyl) -4- (trifluoroethyl) benzene, easy to be strong chemical reaction, such as combustion, explosion and other serious accidents.















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    < It is also necessary to deal with the leakage and emergency management of fire-fighting equipment. If there is an accident, effective measures can be taken immediately to reduce the harm.
    In this case, the storage or 1-% (cyanoethyl) -4- (trifluoroethyl) benzene needs to follow the phase process, and all safety measures need to be taken to ensure human safety and environmental safety.
    What is the preparation method of 1- (isocyanate methyl) -4- (trifluoromethyl) benzene?
    To make 1- (isocyanate methyl) -4- (trifluoromethyl) benzene, the following ancient method can be used:
    First, p-trifluoromethylaniline is used to react with phosgene. The amino activity of p-trifluoromethylaniline is quite good, and the carbonyl chloride part of phosgene has strong electrophilicity. When the two meet, the amino nitrogen atom nucleophilically attacks the carbonyl carbon of phosgene, and the chlorine atom leaves to form an intermediate product. This intermediate product is rearranged within the molecule to form an isocyanate structure, resulting in 1 - (isocyanate methyl) -4- (trifluoromethyl) benzene precursor.
    However, phosgene is highly toxic and needs to be operated under very strict protection. There are also improved methods to replace it with solid phosgene. Solid phosgene is more stable than phosgene, easy to operate, and can also provide carbonyl chloride groups. It reacts with p-trifluoromethylaniline according to a similar mechanism to form the target product.
    The reaction environment is also key. Appropriate organic solvents, such as dichloromethane and toluene, should be selected to facilitate the dissolution and mass transfer of the reactants. The reaction temperature and time need to be carefully adjusted. If the temperature is too high or side reactions occur, if it is too low, the reaction will be delayed. Generally, the temperature is controlled in a moderate range, such as 0-50 degrees Celsius, and it can be adjusted in a timely manner according to the reaction process and monitoring results.
    After the reaction is completed, the separation and purification of the product should not be underestimated. Vacuum distillation can be used to separate the product from the reaction system according to the difference in boiling point between the product and the impurity. Column chromatography can also be used to select suitable stationary and mobile phases to separate the product from the impurity and obtain pure 1- (isocyanate methyl) -4- (trifluoromethyl) benzene.