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1-Isocyanato-4-(Trifluoromethyl)Benzene

1-Isocyanato-4-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    894928

    Chemical Formula C8H4F3NO
    Molecular Weight 187.12
    Appearance Colorless to light yellow liquid
    Boiling Point 197 - 199 °C
    Density 1.32 g/cm³
    Solubility Soluble in organic solvents like toluene, xylene
    Flash Point 82 °C
    Refractive Index 1.475 - 1.477
    Stability Stable under normal conditions, but reacts with water, alcohols

    As an accredited 1-Isocyanato-4-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1 - isocyanato - 4 - (trifluoromethyl)benzene in 500 - gram sealed containers for chemical storage.
    Storage 1 - Isocyanato - 4 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent leakage and exposure to moisture. Store it separately from incompatible substances like amines, alcohols, and water to avoid chemical reactions. Use proper labeling for easy identification.
    Shipping 1 - isocyanato - 4 - (trifluoromethyl)benzene is a hazardous chemical. It must be shipped in accordance with strict regulations, using appropriate packaging to prevent leakage and ensure safe transport to avoid risks to people and the environment.
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    1-Isocyanato-4-(Trifluoromethyl)Benzene 1-Isocyanato-4-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    1 - Isocyanato - 4 - (Trifluoromethyl) Benzene, the best product of chemistry. The development of its product has gone through years. At the beginning, the researchers did not know its properties, but only knew that its molecular structure contained isocyanate radical, trifluoromethyl, and benzene ring. Exploration at that time was like finding a way in the dark night.
    However, the scientific researchers were perseverant. After repeated experiments, the temperature and pressure of the reaction were adjusted by subtle methods, and suitable reagents were selected. Gradually understand the way of its synthesis, and the yield is gradually increased.
    As a result, 1 - Isocyanato - 4 - (Trifluoromethyl) Benzene has made its mark in the chemical industry, contributing to material creation, pharmaceutical research and development, etc., and has finally achieved today's success in the field of chemistry.
    Product Overview
    1-Isocyanate-4- (trifluoromethyl) benzene is a chemical we have worked hard on. Its material has unique properties, and it is often a colorless to slightly yellow transparent liquid with an irritating smell.
    This product is a key raw material in the field of organic synthesis. It can react with many compounds containing active hydrogen, such as alcohols and amines, to form products with special structures and properties. It plays a significant role in the preparation of polymer materials, such as the synthesis of polyurethane. After precise process regulation, polyurethane with different properties can be prepared, which is used in coatings, adhesives, elastomers and many other industries.
    However, it is toxic and corrosive to a certain extent. During operation, strict safety procedures must be followed to ensure the safety of the experimenter and the cleanliness of the environment. Our scientific researchers must exercise caution and conduct in-depth research to make the best use of it, and contribute to the advancement of chemistry and industry.
    Physical & Chemical Properties
    1 - Isocyanato - 4 - (Trifluoromethyl) Benzene is also a chemical substance. Its physical and chemical properties are relevant to the research. The color of this substance is usually a colorless to slightly yellow liquid, and it is clear in appearance. Its taste has a specific smell and can be distinguished by smell.
    In terms of its boiling point, it is about a certain temperature range. Under normal pressure, when it reaches a certain temperature, it changes from liquid phase to gas phase. Its melting point is also a fixed value. When the ambient temperature drops to a certain point, it solidifies from liquid to solid.
    As for solubility, it has different manifestations in many organic solvents. In some polar solvents, it is soluble or partially soluble, and in non-polar solvents, there is also a corresponding miscibility. This is due to the groups contained in its molecular structure, such as isocyanate groups and trifluoromethyl groups, which have unique physical and chemical properties and should be carefully observed by users.
    Technical Specifications & Labeling
    Today there is a product called 1-Isocyanato-4- (Trifluoromethyl) Benzene. Its production method should follow the technical specifications and identification (product parameters). If you want to make this product, you must abide by the procedures, check the materials used, control the degree of reaction, and test the properties of the product in detail.
    Those who standardize the technical method must have the correct matching of materials, and the temperature and time of reaction must be appropriate. The materials used should be the standard of purity, and the weighing is accurate. The reaction device must also be clean and intact. As for the reaction temperature, it cannot be ignored. If it is too high, the product will be variable, and if it is too low, the reaction will be difficult.
    The identification (product parameters) is related to the quality of the product. The color, taste and state must be clear, and the purity and amount of impurities must be detailed. In this way, good products can be obtained and suitable for world use. Those who make this product should take the technical specifications and identification (product parameters) as the key link, and work tirelessly to achieve success.
    Preparation Method
    The preparation method of 1-isocyanate-4- (trifluoromethyl) benzene is related to the raw materials and production process, reaction steps, and catalytic mechanism. The selection of raw materials is very critical, when the compound containing a specific group is used as the starting material. In the reaction step, it is necessary to operate in a precise sequence. First, a reactant is mixed with another reagent at a specific temperature, which is about [X] ° C, and lasts for [X] time to make the initial reaction.
    In the production process, attention should be paid to the cleanliness and stability of the reaction environment. In the catalytic mechanism, the selection of suitable catalysts can greatly improve the reaction rate and yield. [Specific catalyst name] can be used, which can effectively reduce the activation energy of the reaction. Through this series of operations, 1-isocyanate-4- (trifluoromethyl) benzene can be obtained. The optimization of this preparation method is of great significance to the efficient production of this product.
    Chemical Reactions & Modifications
    There is a substance named 1 - Isocyanato - 4 - (Trifluoromethyl) Benzene. In the field of chemistry, its reaction and modification are really important for our research.
    The reaction of this substance often involves the activity of isocyanate groups and can interact with many nucleophiles. If it encounters alcohols, it can form carbamate, which is very important in the preparation of polymer materials and can plastic its structure and properties.
    As for modification, it has unique electronic effects and steric hindrance due to its trifluoromethyl content. Chemical modification can increase its stability and lipophilicity, and can give the product better biological activity and pharmacokinetic properties in the fields of medicine and pesticide research and development. We should study its reaction mechanism in detail and gain insight into the way of modification, so as to expand the application of this substance and contribute to the chemical industry.
    Synonyms & Product Names
    1-Isocyanate-4- (trifluoromethyl) benzene, the synonym and trade name of this substance, is quite important. Its synonyms have various expressions, due to the variety of chemical nomenclature. Or according to its structural characteristics, describe it in precise terms, which is a common method of scientific nomenclature.
    As for the trade name, when the chemical market is in circulation, each merchant may give it a different name according to their own marketing considerations. However, no matter what kind of name, it refers to this specific chemical substance.
    Our chemists often need to clarify various synonyms and trade names in order to communicate and study accurately. This substance is used in the field of chemical synthesis, or as a key raw material for the preparation of polymers with special properties. Therefore, knowing its synonyms and trade names is of great significance in academic research and industrial production.
    Safety & Operational Standards
    1-Isocyanate-4- (trifluoromethyl) benzene, this chemical substance is related to safety and operating standards, and is extremely important and should not be ignored.
    All operations involving this substance must strictly follow specific procedures. In terms of storage, be sure to store it in a cool, dry and well-ventilated place, away from fire and heat sources, and store it separately from oxidants, acids, alkalis and other substances. Do not mix storage to prevent dangerous chemical reactions. During the use process, relevant operators must undergo special training and strictly follow the operating procedures. It is recommended that operators wear self-priming filter gas masks (full masks), tape gas suits, and rubber gloves to avoid direct contact with the substance and cause harm to the body.
    When using the site, suitable containment materials should be provided to prevent leakage accidents. If a leak occurs, personnel from the contaminated area of the leak should be quickly evacuated to a safe area and quarantined, and access should be strictly restricted. Emergency personnel need to wear protective equipment before entering the site. In the event of a small leak, it can be mixed with sand, dry lime or soda ash and collected in a dry, clean and covered container. For large leaks, it is necessary to build a dike or dig a pit to contain, cover it with foam to reduce steam disasters, and then transfer it to a tanker or special collector by pump for recycling or transportation to a waste treatment site for disposal.
    When performing relevant reaction operations, it is necessary to precisely control the reaction conditions, such as temperature, pressure, and the proportion of reactants. Improper conditions can easily cause accidents. At the same time, the operation site needs to be equipped with complete ventilation facilities and emergency rescue equipment, so that in the event of an emergency, it can be responded quickly to ensure the safety of personnel and the environment is not polluted. Only by strictly following these safety and operating standards can we ensure the smooth development of 1-isocyanate-4- (trifluoromethyl) benzene-related work.
    Application Area
    1 - Isocyanato - 4 - (Trifluoromethyl) Benzene, the application field of this substance is quite wide. In the field of material synthesis, it can be used as a key monomer to combine with polyols to obtain polyurethane materials with outstanding properties. This polyurethane can be used in many aspects, such as high-end coatings, coated on the surface of utensils, which can increase its wear resistance and weather resistance; and high-quality adhesives, which can firmly connect different materials.
    In the field of medicine and chemical industry, it also has its own uses. With its special chemical structure, it can be used as an important intermediate to participate in the synthesis of a variety of drugs, laying the foundation for the creation of new specific drugs, which is expected to bring good news to patients. In addition, in the preparation of fine chemical products, it can endow products with unique properties, improve product quality and market competitiveness. It is a widely used and indispensable chemical raw material.
    Research & Development
    1-Isocyanate-4- (trifluoromethyl) benzene, this compound has attracted much attention in our research. We have studied its properties and synthesis methods in detail. After repeated experiments, we have explored many reaction conditions to find the best synthesis path.
    At the beginning, the yield of the synthesis did not meet expectations, so we worked tirelessly to adjust the proportion of reactants, temperature and reaction time. Fortunately, the yield has gradually increased, and the product purity is also good.
    Looking to the future, we hope to extend this achievement. It is hoped that this compound will emerge in the fields of materials science, drug research and development, and promote the development of related industries. We will continue to refine our technology, enhance product quality, pave the way for its wide application, and contribute to the progress of the industry.
    Toxicity Research
    1 - Isocyanato - 4 - (Trifluoromethyl) Benzene is also a chemical substance. When I am studying toxicology, I will investigate its properties in detail. The toxicity of this substance is related to the safety of living beings and cannot be ignored.
    After many experiments, its impact on living organisms has gradually become apparent. If organisms are exposed to this substance, there may be various abnormalities. Looking at its effects on cells, it can cause changes in cell morphology and physiological functions. In animal experiments, the behavior of the tested animals is abnormal, and the organs are also damaged.
    The apparent toxicity is also related to the dose. At small doses, only mild discomfort is seen; with increasing doses, the harm is exacerbated. And different organisms have different tolerances to them, which is a point that needs to be carefully investigated in toxicology research.
    I will continue to study and strive to understand the toxicity mystery of 1 - Isocyanato - 4 - (Trifluoromethyl) Benzene, provide evidence for protection and application, and protect all living beings from its harm, so as to achieve the best use of chemicals without harm.
    Future Prospects
    In the future, 1-Isocyanato-4- (Trifluoromethyl) Benzene will be used to make great use of this chemical material. It can be used in the research of high-tech materials, so that the material has extraordinary characteristics, such as better resistance and weather resistance. It is also expected to develop its capabilities in the synthesis of new materials, adding new materials and adding new tiles. Those who are scientific must study its properties and study its applications in order to achieve good results. In the next few days, it will definitely be able to create a new situation, promote the development of the world, and make great strides. The well-being of the world, and its achievements. The prospect is not limited.
    Where to Buy 1-Isocyanato-4-(Trifluoromethyl)Benzene in China?
    As a trusted 1-Isocyanato-4-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Isocyanato-4-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-isocyanate-4- (trifluoromethyl) benzene?
    1-Isocyanate-4- (triethylamino) tin has a wide range of main uses. In the industrial field, it is often used as a catalyst. This compound can promote many chemical reactions, making the reaction process smoother and more efficient. It is very powerful in the preparation of polyurethane materials.
    Polyurethane materials are now widely used, from building insulation materials to foam materials used in automobile interiors and furniture manufacturing. 1-Isocyanate-4- (triethylamino) tin can adjust the reaction rate and product structure in it, so that polyurethane can have suitable physical properties, such as good elasticity, hardness and durability.
    Furthermore, in some organic synthesis reactions, it can also play a unique catalytic effect. It can promote the formation or breakage of specific chemical bonds, assist in the synthesis of complex organic molecular structures, and contribute to the development of organic synthesis chemistry. For example, in the preparation of some fine chemicals, with its catalytic effect, it can achieve efficient and accurate synthesis, improve product yield and purity.
    In the coatings and adhesives industry, this compound also has outstanding performance. It can participate in the curing reaction of coatings and adhesives, improve their performance, enhance the adhesion, wear resistance and chemical corrosion resistance of coatings, so that coatings and adhesives can maintain good use in different environments, thus widely used in construction, automobiles, ships and other fields to protect the surface of objects and enhance the bonding strength between objects.
    What are the physical properties of 1-isocyanate-4- (trifluoromethyl) benzene?
    1-% cyanate-4- (triethylmethyl) silicon, which is one of the silicon compound family, its physical properties are characteristic, and are described below.
    First, its external surface, often a transparent liquid, such as clear water, under the current, it can have good flow performance, uniform surface area, floating surface or sediment. This external property is suitable for multiplexing applications and provides a good operating base.
    Second boiling rate, under normal circumstances, its boiling rate is limited to a specific temperature, and this boiling rate makes it possible to reduce the temperature of a liquid under a specific temperature. This property is very important in chemical operation processes such as steaming and separation. It can be effectively divided into other substances according to its boiling characteristics.
    Furthermore, in terms of density, 1-% cyanate-4- (triethyl) silicon has a certain density, and the density value is different from that of a normal solution or reaction material. In the reaction system, because of its density characteristics, it can affect the mixing and separation of substances. In the reaction process, this factor needs to be carefully considered in order to ensure the protection of the reverse industry.
    Solubility is also one of the important physical properties. It exhibits different degrees of solubility in various soluble systems, and can be soluble in certain kinds of soluble or non-soluble materials. This property is advantageous for its use as a reaction material or additive. It is uniformly dispersed in the soluble system, and it can be used for anti-reaction or specific functions.
    In addition, the solubility of 1-% cyanate-4- (triethylmethyl) silicon cannot be ignored. Under normal conditions, it is not an easy thing to lose, but there is still a certain rate. This property needs to be properly controlled during the storage and use process to prevent the material from being lost or affected by the environment.
    What should be paid attention to when storing and transporting 1-isocyanate-4- (trifluoromethyl) benzene?
    When storing and transporting 1-isocyanate-4- (triethylamino) silicon, it is necessary to pay attention to many key matters.
    When storing it, the temperature and humidity of the environment are the first. This material is delicate, and high temperature can easily cause its activity to change, or even cause undesirable changes such as decomposition. Therefore, it should be stored in a cool place, and the temperature should be controlled within a specific range, not higher than [X] ° C. And the humidity should not be too high. If it is too humid or causes it to deteriorate by moisture, the storage space should be kept dry, and the relative humidity should not exceed [X]%.
    Furthermore, the storage place must be well ventilated. If this substance evaporates and accumulates in a closed space, or causes the local concentration to be too high, adding a safety hazard. Therefore, unobstructed ventilation facilities are required to ensure the circulation of air and disperse volatile gases.
    Also pay attention to the material selection of the storage container. Due to its active chemical properties, some materials may react with it. It is advisable to use specific corrosion-resistant materials, such as stainless steel, specific plastics, etc., and the container must be well sealed to prevent leakage.
    As for the transportation process, it should not be underestimated. The transportation tool should be clean and dry, and no impurities that can react with it should be left. During transportation, the temperature should be strictly controlled to maintain stability, and the vibration and collision should be avoided too violently to prevent the package from being damaged and leaking.
    At the same time, transportation personnel must be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. In the event of an accident such as a leak, it can be disposed of quickly and properly to minimize the harm. In short, the storage and transportation of 1-isocyanate-4 - (triethylamino) silicon needs to be carefully controlled from various aspects such as the environment, containers, and operating specifications to ensure safety.
    What are the synthesis methods of 1-isocyanate-4- (trifluoromethyl) benzene?
    To prepare 1-isocyanate-4- (triethylamino) benzene, the following methods are used:
    First, the corresponding halogenated aromatic hydrocarbon is used as the starting material. First, the benzene derivative containing the halogen atom is taken, and the nucleophilic substitution reaction is carried out with the triethylamine under the condition of moderate temperature and catalyst assistance. In this process, the halogen atom is combined with the nitrogen atom in the triethylamine to form an intermediate product. Then the isocyanate is introduced, which can be obtained by reacting with phosgene or other reagents containing the isocyanate source. However, phosgene is highly toxic, and the operation needs to be cautious, and it should be done under specific equipment and protection.
    Second, starting from the benzene compound containing amino groups. First, the amino benzene is interacted with triethylamine hydrochloride to connect the amino group to the triethylamino group. In this step, it is often necessary to choose a suitable base agent to promote the reaction to the right. Then the amino group is converted into isocyanate, which can be achieved by diazotization, and then reacting with cyanate. This path step is slightly complicated, but the raw materials are relatively easy to obtain, and some reaction conditions are milder.
    Third, start with compounds with other easily convertible groups on the benzene ring. For benzene derivatives containing hydroxyl or carboxyl groups, first convert the hydroxyl or carboxyl group into a suitable leaving group, and then react with triethylamine to access the triethylamino group. Then, through appropriate reaction, isocyanate is introduced. This approach requires careful design of each step according to the characteristics of the starting material to achieve the purpose of efficient synthesis.
    When synthesizing, it is necessary to pay attention to the reaction conditions of each step, such as temperature, pH, reaction time, etc., which are all related to the yield and purity of the product. And each method has its own advantages and disadvantages, and should be used according to the actual situation, such as raw material availability, cost, equipment conditions, etc.
    What are the effects of 1-isocyanate-4- (trifluoromethyl) benzene on the environment and human health?
    1-Isocyanate-4- (triethylamino) matte is a special chemical substance. Its impact on the environment and human health is of great concern to the world.
    At the environmental level, if this substance is accidentally released in nature, it may cause harm to ecological elements such as water bodies and soils. Its chemical activity is quite high, or it reacts with many substances in the environment. For example, when exposed to water, it is easy to hydrolyze, generating irritating products, which then pollute the water source and pose a threat to the survival and reproduction of aquatic organisms. And it persists in the soil, or changes the chemical properties of the soil, affecting the absorption of nutrients by plant roots and hindering plant growth.
    As for human health, this substance has certain toxicity to the human body. Inhalation through the respiratory tract can irritate the mucosa of the respiratory tract, causing symptoms such as cough and asthma. Long-term exposure can even damage lung function. If exposed through the skin, it can cause skin allergies, redness, swelling, itching and other discomforts. If ingested carelessly, it will damage the digestive system, lead to nausea, vomiting, abdominal pain and other conditions, and in severe cases, life-threatening.
    To sum up, 1-isocyanate-4 - (triethylamino) matte has potential adverse effects on the environment and human health. Therefore, during its production, use and storage, it is necessary to strictly abide by the operating procedures and strengthen protective measures to reduce its harm to the environment and human health.