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1-Iodo-3-Trifluoromethoxy-Benzene

1-Iodo-3-Trifluoromethoxy-Benzene

Hongda Chemical

Specifications

HS Code

893196

Chemical Formula C7H4F3IO
Molecular Weight 286.006
Appearance liquid (usually)
Boiling Point around 190 - 200 °C (approximate)
Density around 1.9 - 2.1 g/cm³ (approximate)
Solubility In Water insoluble
Solubility In Organic Solvents soluble in common organic solvents like dichloromethane, toluene
Vapor Pressure low at room temperature
Flash Point elevated, potentially around 80 - 90 °C (approximate)
Stability stable under normal conditions, but reactive with strong oxidizing agents

As an accredited 1-Iodo-3-Trifluoromethoxy-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - iodo - 3 - trifluoromethoxy - benzene in a sealed, chemical - resistant bottle.
Storage 1 - iodo - 3 - trifluoromethoxy - benzene should be stored in a cool, dry, and well - ventilated area. Keep it away from heat sources, open flames, and strong oxidizing agents. Store in a tightly sealed container to prevent vapor leakage. Due to its potential reactivity and toxicity, it should be separated from incompatible substances. Label the storage container clearly for easy identification and safety handling.
Shipping 1 - iodo - 3 - trifluoromethoxy - benzene is shipped in sealed, corrosion - resistant containers. Shipment follows strict chemical transport regulations, ensuring proper handling and storage to prevent spills and maintain product integrity during transit.
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1-Iodo-3-Trifluoromethoxy-Benzene 1-Iodo-3-Trifluoromethoxy-Benzene
General Information
Historical Development
1 - Iodo - 3 - Trifluoromethoxy - Benzene is also a product of chemistry. Its historical development has a long history. At the beginning, the academic community has been studying in the field of organic chemistry more and more deeply, and many talents wanted to explore the mysteries of fluorinated organic compounds. At that time, everyone was dedicated to finding novel synthesis paths in order to create this unique substance.
After many years and countless experiments, scholars have continuously improved the reaction conditions and optimized the ratio of raw materials. From the initial difficult attempts to gradually mastering the key steps, every step has been painstaking. First, it was found that a specific catalyst can promote the reaction, and then the appropriate temperature and pressure range was explored.
Today, 1 - Iodo - 3 - Trifluoromethoxy - Benzene has emerged in the fields of medicine, materials science and other fields, and its historical development has witnessed the unremitting exploration and progress of chemical research.
Product Overview
1-Iodo-3-Trifluoromethoxy-Benzene, the organic compound is also. It is a colorless liquid with a special odor. In the structure of this compound, the iodine atom is connected to the benzene ring containing the trifluoromethoxy group, and the unique structure gives it special chemical properties.
In the field of organic synthesis, 1-Iodo-3-Trifluoromethoxy-Benzene has a wide range of uses. It can be used as an intermediate to participate in a variety of organic reactions, and the functional group transformation on the benzene ring is realized by the activity of the iodine atom. Because of its trifluoromethoxy group, it can introduce fluorine-containing groups, giving the product special physical and chemical properties, such as enhancing the stability and lipophilicity of the compound.
Preparation of this compound requires a fine chemical process, following specific reaction paths and conditions to ensure the high efficiency of the reaction and the purity of the product. Its research and development has potential value and significance in many fields such as medicine and materials, and can promote the progress and development of related science and technology.
Physical & Chemical Properties
1-Iodo-3-Trifluoromethoxy-Benzene is a very important compound in organic synthesis. Its physical properties are unique. It is mostly liquid at room temperature, with a specific boiling point and melting point. The boiling point is about a certain range, and the melting point is also in a specific range. This property is convenient for separation and purification according to temperature during the synthesis process.
On its chemical properties, the iodine atom in this compound is highly active, prone to nucleophilic substitution, and can react with many nucleophilic reagents such as alkoxides and amines to generate various derivatives. The existence of trifluoromethoxy gives it certain stability and unique electronic effects, which affects its reactivity and selectivity. This compound may be used as a key intermediate in the field of medicinal chemistry to construct molecular structures with specific biological activities, providing an important material basis for innovative drug research and development.
Technical Specifications & Labeling
1-Iodo-3-Trifluoromethoxy-Benzene is an important chemical product. Its process specifications are related to many factors. The appearance of this compound needs to be pure and free of impurities, and the color must be translucent. The purity must reach the highest standard, and the impurity content should be strictly controlled in the very low range.
As far as the label is concerned, the name of 1-Iodo-3-Trifluoromethoxy-Benzene should be clearly marked on the product packaging, and accurate chemical information should be attached, such as molecular formula, molecular weight and other parameters. Warning labels are also indispensable to clarify its chemical properties and latent risk, to ensure that the user can dispose of it correctly.
The reaction conditions involved in the process specifications need to be precisely controlled for temperature, pressure and reaction time to ensure the stability and uniformity of product quality. In this way, 1-Iodo-3-Trifluoromethoxy-Benzene can show its excellent performance in various application scenarios.
Preparation Method
1-Iodo-3-Trifluoromethoxy-Benzene is an important organic compound. The preparation method and the selection of raw materials are crucial. Compounds containing benzene rings are often used as starting materials, such as specific halogenated benzene derivatives, and halogen atoms need to be precisely positioned, which lays the foundation for subsequent reactions.
In the synthesis process, the halogenation reaction is first carried out. By skillfully adjusting the reaction conditions, such as temperature, catalyst type and dosage, the halogen atom is replaced at a specific position of the benzene ring to obtain a specific halogenated benzene intermediate. Then trifluoromethoxy is introduced. This step can be achieved by a specific nucleophilic substitution reaction. The nucleophilic reagents are carefully selected, and the reaction time and pH are strictly controlled to ensure that the reaction is efficient and selective.
The monitoring of the reaction process is extremely critical. Each step requires the use of means such as thin-layer chromatography and nuclear magnetic resonance to monitor the reaction process in real time to ensure that the reaction proceeds according to the expected path. The production of the product needs to be finely separated and purified to obtain high-purity 1-Iodo-3-Trifluoromethoxy-Benzene to meet the needs of scientific research and production.
Chemical Reactions & Modifications
In recent years, the study of chemical things, in 1-Iodo-3-Trifluoromethoxy-Benzene this thing, quite laborious. Its chemical response, at first, the rate is according to the conventional method, but the effect obtained is not exquisite.
The response of chemistry, if the boat is traveling on the water, the wind direction and water flow can be controlled. 1-Iodo-3-Trifluoromethoxy-Benzene, although the nature is fixed, the environment and the agent used can make it change. At the beginning of the normal method, or due to the improper amount of agent, or due to the unsuitable temperature, it should not be expected.
After thinking carefully, observe its nature and fine-tune the method used. The matching of the change agent, the degree of temperature control, is like a good ruler, adjusting the reins of the horse, and driving it according to its nature. Fruit, it should be gradually improved, and the quality should also rise. This is the change that requires chemical response and transformation, and the change that comes from thinking, is also what the researcher should strive for.
Synonyms & Product Names
When you hear something, it is called 1-Iodo-3-Trifluoromethoxy-Benzene. The name of this substance is also synonymous with the name of the commodity, which is quite important.
In the field of chemistry, there are many things, which is a common thing. The name of the synonym can help scholars and researchers to express the meaning accurately and without ambiguity when communicating. The name of the commodity is related to the market circulation, which is easy for merchants and users to identify.
1-Iodo-3-Trifluoromethoxy-Benzene, or have another name to meet the needs of different scenes. The name of the synonym is determined according to the chemical properties and structural characteristics, so that everyone in the academic circle can know its essence when they hear it. And the name of the commodity may pay more attention to simplicity and easy to remember, so as to facilitate promotion.
For our chemical researchers, only by clarifying the synonymous name of this thing and the name of the product can we study and apply it smoothly and avoid mistakes. In this way, we can obtain its true meaning, make good use of it, and contribute to the progress of chemistry.
Safety & Operational Standards
1 - Iodo - 3 - Trifluoromethoxy - Benzene is an important chemical substance, which needs to be discussed in detail in terms of its safety and operating practices.
When preparing this substance, the use of all raw materials should be strictly measured. The utensils used must be clean and dry to prevent impurities from mixing, causing reaction deviations, affecting the purity of the product, and more importantly, the safety of subsequent use. During the reaction process, temperature control is extremely critical. If the temperature is too high, or the reaction is excessive, there is a risk of danger; if the temperature is too low, the reaction will be slow or even stagnant. Therefore, it is necessary to use subtle methods to keep the temperature constant in a suitable range.
The operating environment cannot be ignored. It is necessary to ensure good ventilation, because the substance or volatilized harmful gases, if accumulated in the room, endanger the health of the operator. And the operation place should be away from the fire source and hot topic, this substance has certain flammability, in case of open flame, hot topic, fear of fire, even explosion.
Storage should be placed in a cool, dry and ventilated place. Store in a sealed container to avoid contact with air and moisture to prevent its deterioration, and also keep the storage safe. When using, when using special tools, take the standard operation according to the accurate quantity, and do not do it at will.
When using this substance, the operator must wear appropriate protective equipment, such as protective clothing, gloves, goggles, etc., to protect himself from direct contact with the substance and prevent it from causing damage to the skin, eyes, etc. After the operation, the cleaning of the appliance and the disposal of the waste should follow strict regulations and should not be discarded at will, so as not to pollute the environment and leave behind potential safety hazards. In this way, the safety of 1-Iodo-3-Trifluoromethoxy-Benzene related operations must be guaranteed, so that the research and other work can be carried out smoothly.
Application Area
1-Iodo-3-Trifluoromethoxy-Benzene, organic compounds are also. Its application field is quite functional in the field of medicinal chemistry. It can be used as a key intermediate in pharmaceutical synthesis to help create new specific drugs. In the field of material science, it is also promising. Based on this compound, materials with specific properties may be developed, such as materials with excellent photoelectric properties, which can be used in the manufacture of optoelectronic devices. And in the field of pesticide chemistry, it may be used to develop high-efficiency and low-toxicity pesticides, protect crop growth, and reduce the disturbance of pests and diseases. It shows unique potential in many application fields, opening up new paths for scientific research and industrial production, waiting for researchers to explore in depth to make the best use of it.
Research & Development
In modern times, chemistry has advanced, and material research has become more and more prosperous. 1-Iodo-3-Trifluoromethoxy-Benzene this material, it is the object of our dedicated study. Its properties are different, and it often shows different effects in various reaction mechanisms.
Our generation studied the truth, observed its structure, and analyzed its reaction path. After months of experiments, we found an optimal method for synthesis, and the yield also increased compared with before. And under different environments, the stability and activity changes are carefully reviewed.
Looking at its application prospects, there are countless possibilities in the fields of pharmaceutical chemistry and materials science. In the future, we should explore in depth, with the aim of expanding its application, adding bricks and mortar to the academic community and industry, and promoting the use of this substance in the process of research and application.
Toxicity Research
I have been studying chemical substances for a long time, and now I take 1-Iodo-3-Trifluoromethoxy-Benzene as an example to study its toxicity. This compound is gradually emerging in the field of chemical industry, but its toxicity cannot be ignored.
Looking at the structure of its molecules, iodine and trifluoromethoxy coexist, or cause unique properties. I checked the classics in detail, the experimental data is still lacking, but compared with the same kind, halogens and fluoroalkoxy are often toxic. The genus of iodine may be involved in human metabolism, and the sex of trifluoromethoxy is active, or it involves biochemical changes, which damage the energy of cells and disrupt the order of physiology.
Although it has not been confirmed, the doubt of toxicity should not be ignored. Those who study this substance must strictly abide by the regulations to protect their own safety and prevent its escape. I also hope that the follow-up research will clarify the details of its toxicity, so that those who use this product can take the right path to avoid its disaster, protect the prosperity of the chemical industry, and protect the health of all living beings.
Future Prospects
1-Iodo-3-Trifluoromethoxy-Benzene, it is also a thing of transformation. I have studied it here, and I think about the development of its future, and I hope for it.
Today, this thing is mostly used for general synthesis, and its characteristics are special, and it can be new in the way of synthesis. If it is not developed, it may be able to make a big impact on the field of research. Seeking new knowledge, the characteristics of this compound may be exquisite for researchers, and it can solve the suffering of the world.
And it can also be used in materials science. Or it can be used in high-tech to promote its progress.
I believe that with the efforts of researchers in the next few days, 1-Iodo-3-Trifluoromethoxy-Benzene will be able to develop their talents, and they will be able to develop their talents in many fields.
Where to Buy 1-Iodo-3-Trifluoromethoxy-Benzene in China?
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Frequently Asked Questions

As a leading 1-Iodo-3-Trifluoromethoxy-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Iodo-3-Trifluoromethoxy-Benzene?
1-Iodine-3-trifluoromethoxybenzene is also an organic compound. It has a wide range of uses, especially in the field of organic synthesis.
First, in the field of pharmaceutical chemistry, it is often a key intermediate. In the process of drug development, many compounds with specific physiological activities need to be constructed as starting materials. Through ingenious chemical reactions, various functional groups are added to shape specific molecular structures, thereby creating new drugs. For example, when developing drugs with antiviral and anti-tumor effects, the unique structure of 1-iodine-3-trifluoromethoxybenzene can endow the final product with excellent biological activity and pharmacokinetic properties.
Second, in the field of materials science, it also has outstanding performance. In the process of synthesizing special polymer materials, it can be introduced as a functional monomer. Because it contains iodine and trifluoromethoxy functional groups, it can significantly change the physical and chemical properties of polymer materials, such as improving the thermal stability, chemical stability and electrical properties of the material. For example, when preparing high-performance electronic packaging materials or special optical materials, the addition of this compound can optimize the comprehensive properties of the material and meet the strict requirements of high-end science and technology.
Third, it is also indispensable in pesticide chemistry. As an important building block for the synthesis of new pesticides, it can effectively improve the biological activity of pesticides and environmental compatibility. With its structural characteristics, pesticide products with high selectivity, low toxicity and high efficiency against specific pests or pathogens can be designed and synthesized, thus contributing to the sustainable development of agriculture.
What are the physical properties of 1-Iodo-3-Trifluoromethoxy-Benzene?
1-Iodine-3-trifluoromethoxylbenzene is an important compound in the field of organic chemistry. Its physical properties are quite characteristic. Under normal temperature and pressure, it is usually in a liquid state. This state is affected by intermolecular forces. The structure of the iodine atom and the trifluoromethoxy group in the molecule makes it have a specific intermolecular attractive force and repulsion balance, so it is in a liquid state.
Looking at its color, it is generally colorless to light yellow. This color is due to the absorption and reflection characteristics of the molecular structure to light. The energy level of the electron transition in the molecule is in a specific range of the visible part, which makes the compound appear this color.
When it comes to smell, it often has a special organic smell. However, this smell is difficult to describe accurately. Because the human sense of smell is complex, and different individuals may experience it differently. However, the special smell of its gas is due to the unique chemical structure and volatility of the molecule.
The boiling point and melting point of this compound also have characteristics. The boiling point is relatively high, about [X] ° C. Due to the presence of iodine atoms and trifluoromethoxy groups in the molecule, it enhances the intermolecular force, and more energy is required to cause gasification. The melting point is about [X] ° C. The molecular structure regularity and intermolecular forces work together to determine this melting point value.
Its density is greater than that of water, about [X] g/cm ³, which is determined by the relative mass of the molecule and the way of molecular accumulation. The heavier atoms in the molecule such as iodine and the special group trifluoromethoxy make it denser.
In terms of solubility, 1-iodine-3-trifluoromethoxy benzene exhibits good solubility in organic solvents such as dichloromethane and tetrahydrofuran. Due to the principle of "similar miscibility", its molecular structure has similar polarity characteristics to that of organic solvents. However, its solubility in water is poor. Because of the large difference between the polarity of the molecule and the polarity of the water molecule, it is difficult for the two to dissolve each other.
The above physical properties are of great significance in many fields such as organic synthesis and materials science. Understanding their properties can help researchers effectively carry out relevant experiments and applications.
What is 1-Iodo-3-Trifluoromethoxy-Benzene synthesis method?
The synthesis of 1-iodine-3-trifluoromethoxybenzene is a key issue in organic synthetic chemistry. To make this substance, several common chemical pathways can be followed.
One is to start with phenolic compounds. First, the phenolic compound is protected by an appropriate protective group to prevent it from being affected in subsequent reactions. Then, it is reacted with trifluoromethylation reagents. Common trifluoromethylation reagents, such as trifluoromethylsulfonic anhydride, can be replaced by trifluoromethoxy in the presence of suitable bases and catalysts to form intermediates containing trifluoromethoxy. In this step, the choice of bases is very important, such as potassium carbonate, potassium tert-butanol, etc. Different bases may have differences in reactivity and selectivity. The type of catalyst also affects the reaction process, such as some transition metal catalysts can promote the reaction.
After obtaining this intermediate, the iodization reaction can be carried out. The iodization reaction can be achieved by iodizing reagents, such as iodine elemental substance combined with appropriate oxidants, such as hydrogen peroxide and iodine elemental substance. Under suitable solvents and reaction conditions, iodine atoms can be introduced into specific positions on the benzene ring to generate 1-iodine-3-trifluoromethoxylbenzene. The choice of solvent cannot be ignored. Common organic solvents such as dichloromethane, N, N-dimethylformamide, etc., have an impact on the rate of reaction and the purity of the product.
Another way is to use halogenated benzene as the starting material. Under metal catalysis, the halogenated benzene undergoes a nucleophilic substitution reaction with the trifluoromethoxylation reagent, so that the trifluoromethoxy group is introduced into the benzene ring. Commonly used metal catalysts such as palladium catalysts can effectively promote this reaction under the synergistic action of ligands. Subsequently, the obtained intermediate is iodized and modified. By adjusting the reaction conditions and reagents, the final product 1-iodine-3-trifluoromethoxylbenzene is synthesized. In this pathway, factors such as the ratio of metal catalyst to ligand, reaction temperature and time need to be finely regulated to obtain the ideal yield and purity.
1-Iodo-3-Trifluoromethoxy-Benzene What are the precautions during storage and transportation?
For 1-iodine-3-trifluoromethoxybenzene, all precautions are essential during storage and transportation.
First words storage, this substance should be placed in a cool, dry and well-ventilated place. Due to its nature or sensitivity to temperature and humidity, if it is placed in a high temperature and humid place, it may deteriorate. And it must be kept away from fires and heat sources. Because of its flammability, it is prone to danger in case of open flames and hot topics. It should be stored separately from oxidizing agents, acids, bases, etc., and must not be mixed to prevent chemical reactions, damage its quality, and even risk safety. At the same time, the warehouse should be equipped with suitable materials for containing leaks for emergencies.
As for transportation, it should not be ignored. The transportation vehicle must ensure that the vehicle is in good condition and has corresponding fire protection and emergency treatment equipment. During transportation, it should be protected from exposure to the sun, rain and high temperature. When loading and unloading, the operator should be light and light, and it is strictly forbidden to drop and heavy pressure to avoid package damage and material leakage. During transportation, it should be driven according to the specified route, and do not stop in densely populated areas and residential areas. And the transportation enterprise must have corresponding qualifications, and the transportation personnel should also undergo professional training, familiar with the characteristics of the substance and emergency treatment methods, so as to ensure the safety of storage and transportation.
What is the market price of 1-Iodo-3-Trifluoromethoxy-Benzene?
1-Iodine-3-trifluoromethoxylbenzene, the price of this product in the market is difficult to determine. Due to changing market conditions, the price varies with many reasons.
Its price may be related to output. If there are many producers, the market is full of goods, and the price may decline; if there are few producers, and the goods are scarce and the demand is large, the price may rise. Furthermore, the price of raw materials is also the key. Raw materials are rare, and the price is high. If the cost of 1-iodine-3-trifluoromethoxylbenzene increases, the price in the market is also high; conversely, raw materials are easy to obtain and cheap, and the price may be low.
In addition, the amount of demand also affects its price. In the chemical industry, if the demand for 1-iodine-3-trifluoromethoxybenzene suddenly increases, the supply exceeds the demand, and the price will rise; if there is no demand, the supply exceeds the demand, and the price will fall.
And the difficulty of the process, the cost of transportation, and the regulations of taxes and fees all affect the price. The refining technology is excellent, the yield is high, the cost is reduced, and the price may be favorable; however, the transportation distance, the high cost, or the change in taxes and fees can cause the price to change in the market.
To sum up, if you want to know the market price of 1-iodine-3-trifluoromethoxybenzene, you must carefully observe the current market conditions and consult merchants and operators before you can obtain a more accurate price.