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1-Iodo-3,5-Difluoro-4-Bromobenzene

1-Iodo-3,5-Difluoro-4-Bromobenzene

Hongda Chemical

Specifications

HS Code

644138

Chemical Formula C6H2BrF2I
Molar Mass 329.885 g/mol
Appearance Solid (likely, based on similar haloarenes)
Solubility In Water Low (hydrophobic due to non - polar benzene ring and halogen atoms)
Solubility In Organic Solvents Likely soluble in common organic solvents like dichloromethane, chloroform
Purity Depends on manufacturing process
Stability Stable under normal conditions, but may react with strong nucleophiles or reducing agents
Vapor Pressure Low (due to its non - volatile nature as a solid or high - boiling liquid)

As an accredited 1-Iodo-3,5-Difluoro-4-Bromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - iodo - 3,5 - difluoro - 4 - bromobenzene packaged in a sealed glass bottle.
Storage 1 - iodo - 3,5 - difluoro - 4 - bromobenzene should be stored in a cool, dry, well - ventilated area, away from sources of heat and ignition. Keep it in a tightly sealed container, preferably made of a material resistant to chemical corrosion, such as glass or certain plastics. Store separately from oxidizing agents and reactive substances to prevent potential chemical reactions.
Shipping 1 - iodo - 3,5 - difluoro - 4 - bromobenzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict chemical transportation regulations to ensure safe transit, minimizing risks during handling and movement.
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1-Iodo-3,5-Difluoro-4-Bromobenzene 1-Iodo-3,5-Difluoro-4-Bromobenzene
General Information
Historical Development
1 - Iodo - 3,5 - Difluoro - 4 - Bromobenzene is an important chemical product. Its historical development can be traced back to the past. Early chemical explorers worked tirelessly to explore new compounds in the journey of material research. At the beginning, the understanding of halogenated aromatic hydrocarbons was still shallow, but many scholars were not afraid of difficulties and continued to study.
At that time, the experimental conditions were simple and the tools were crude. However, scholars gradually explored the method of synthesizing this compound with perseverance. After repeated experiments and countless failures, some progress was finally made. With the passage of time, technology has gradually advanced, equipment has been improved, and the synthesis process has also been perfected. From its initial accidental discovery to its precise preparation today, the historical development of 1-Iodo-3,5-Difluoro-4-Bromobenzene is a vivid portrayal of the unremitting progress and exploration in the field of chemistry.
Product Overview
1 - Iodo - 3,5 - Difluoro - 4 - Bromobenzene is an important chemical product. Its characteristics are unique, its appearance is [specific appearance, can be supplemented], and it has specific physical and chemical properties. This compound is widely used in the field of organic synthesis, and can be used as a key intermediate to participate in the construction of many complex organic molecules.
In terms of structure, the clever arrangement of iodine, fluorine and bromine atoms on the benzene ring gives it special reactivity. The introduction of iodine atoms makes the product exhibit unique properties in nucleophilic substitution reactions; the presence of fluorine atoms enhances the stability and electronic effects of the molecule; bromine atoms can be used as a leaving group under specific reaction conditions to open a variety of reaction paths.
During the preparation process, the reaction conditions need to be carefully regulated to ensure the purity and yield of the product. Because of its great potential in cutting-edge fields such as medicinal chemistry and materials science, in-depth study of it, and exploration of better synthesis strategies and application expansion are of great significance to the development of chemistry.
Physical & Chemical Properties
1-Iodo-3, 5-Difluoro-4-Bromobenzene, organic compounds are also. Its physical and chemical properties are worth exploring. Looking at its physical properties, at room temperature, or as a solid, with a specific color and state. The genus of melting point and boiling point are the keys to characterizing its physical properties. Its melting also requires a specific temperature to turn solid into liquid. The boiling point also has a fixed number. When it reaches this temperature, it liquefies into gas.
On its chemical properties, it is active because it contains halogen atoms of iodine, fluorine and bromine. It can react with many reagents, and is a genus of nucleophilic substitution, or is common. The structure of the benzene ring also affects its reaction properties. When encountering nucleophilic reagents, halogen atoms may be replaced to form new compounds.
All these physical and chemical properties are of great significance in various fields such as organic synthesis and materials science, and are the cornerstones of scientific research and industrial applications.
Technical Specifications & Labeling
1 - Iodo - 3,5 - Difluoro - 4 - Bromobenzene is an important chemical substance. Its process specifications and identification (product parameters) are extremely critical. In terms of process specifications, the synthesis steps need to be accurate. From the selection of raw materials, the proportion of each reactant needs to be strictly controlled. Such as reaction temperature and duration also affect product quality. On the label (product parameters), its purity needs to be clarified, which is related to its effect in various reactions. And its appearance characteristics should also be clearly marked, such as color and morphology. The impurity content needs to be accurately determined and explained to ensure the quality of the product is stable and can meet the needs of different uses, so that this product can play its due value in the chemical field.
Preparation Method
To prepare 1 - Iodo - 3,5 - Difluoro - 4 - Bromobenzene, the raw materials and production process, reaction steps, and catalytic mechanism are the key.
First take an appropriate amount of fluorobenzene, use bromine as brominating agent, and under the catalysis of iron filings, control the temperature to about 50 to 60 degrees Celsius, and a bromination reaction occurs to obtain 3,5 - difluorobenzene. In this step, attention should be paid to the control of the reaction rate and temperature to prevent side reactions.
Then, 3,5-difluorobromobenzene is combined with an iodine-substituted reagent, such as potassium iodide, in a specific organic solvent, such as N, N-dimethylformamide, an appropriate amount of catalyst, such as copper powder, is added, and heated to 100 to 120 degrees Celsius. During the reaction, continue to stir to ensure that the reactants are fully contacted.
After the above steps, the crude product is purified by distillation, recrystallization, etc., to obtain high purity 1-Iodo-3,5-Difluoro-4-Bromobenzene. Precise operation of each step of the reaction can ensure the quality and yield of the product according to the standard process.
Chemical Reactions & Modifications
1 - Iodo - 3,5 - Difluoro - 4 - Bromobenzene is an important organic compound. In the field of chemical synthesis, its chemical reaction and modification have always attracted the attention of our chemical researchers.
Looking at its chemical reaction, this compound can be prepared by halogenation reaction. The substitution position and order of halogen atoms have a great impact on the purity and yield of the product. For example, under specific reaction conditions, the substitution of iodine atoms, fluorine atoms and bromine atoms requires precise regulation of the reaction temperature, catalyst type and dosage to obtain the ideal product.
As for its modification, in order to improve the properties of this compound, it can be achieved by introducing specific functional groups. Or react with compounds containing active hydrogen to change the molecular structure, thereby giving it new properties such as better solubility and stability. This compound may have potential application value in materials science, medicinal chemistry and other fields, so it is necessary to study its chemical reaction and modification in depth.
Synonyms & Product Names
1 - Iodo - 3,5 - Difluoro - 4 - Bromobenzene This product is very important in my chemical research. Its synonym and trade name also need to be added in detail.
In the past, various sages studied in the field of chemistry, and the names of this product gradually became similar and different. Or because of its properties, production methods, or according to its use and origin, the names vary. Looking at its synonyms is to reveal the characteristics of this product.
As for the name of the product, it is the order of the merchant to recognize its characteristics and facilitate its circulation. Although the names agreed upon by each party are different, they are all related to the origin of this product. If its structure is exquisite, or it is unique in the reaction, the merchant will choose it with a good name, hoping to win favor in the city.
We are chemical researchers. When we understand the similarities and differences between the name of this object and the name of the product, it is very beneficial for academic inquiry and industrial application. As the ancient saying goes, only by observing the change of its name and understanding its quality can we advance step by step in the path of chemistry and explore more profound principles.
Safety & Operational Standards
1 - Iodo - 3,5 - Difluoro - 4 - Bromobenzene is an important chemical substance. In its safe production and operation, many norms need to be strictly followed.
The first word is safe. This substance has certain potential hazards. When storing, it should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because it may be harmful to the human body, protective measures are essential when contacting. Operators wear protective gloves and goggles in front of suitable protective clothing to avoid skin and eye contact. In case of accidental contact, rinse with plenty of water immediately and seek medical attention in time.
In terms of operating norms, experimental operations must be carried out in a professional laboratory under qualified ventilation equipment. Before use, check whether the experimental instrument is intact in detail to ensure that there is no risk of leakage during operation. When weighing and transferring the substance, the action should be precise and gentle to prevent it from spilling. During the experiment, strictly control the reaction conditions, such as temperature, pressure, reaction time, etc., and operate cautiously according to the established experimental steps.
Disposal of waste should not be ignored. The remaining 1 - Iodo - 3,5 - Difluoro - 4 - Bromobenzene and related wastes in the experiment should not be discarded at will. They should be collected in accordance with relevant environmental protection regulations and properly disposed of to prevent pollution to the environment.
In conclusion, the safe production and operation practices for 1 - Iodo - 3,5 - Difluoro - 4 - Bromobenzene are related to personnel safety and environmental quality, and require high attention and meticulous implementation by chemical practitioners.
Application Area
1 - Iodo - 3,5 - Difluoro - 4 - Bromobenzene This compound has a wide range of application fields. In the field of pharmaceutical research and development, it can be used as a key intermediate to help synthesize drugs with unique pharmacological activities or drugs with curative effects on specific diseases. In the field of materials science, it can be used to prepare functional materials, such as materials with special optical or electrical properties, to meet the needs of different fields such as electronic devices, optical instruments, etc.
Gu Yun: "Each thing has its own use, and each material is suitable for its own use." This compound is like a special material and plays its unique functions in various fields. Although its appearance is not impressive, it can make waves in the world of medicine and materials, help researchers achieve their goals, benefit the world, and develop its unique value and charm for the benefit of future generations.
Research & Development
In recent years, Yu has been paying attention to the research of chemical products. Today there is 1-Iodo-3, 5-Difluoro-4-Bromobenzene this product, its nature is different, and it has great potential in various fields.
Yu began to study it, carefully examining its structure and exploring its rationale. After repeated experiments, analyzing the rules of its reaction, seeking better methods to control it. At the beginning, the yield was not good, but I was not discouraged. Repeatedly adjusting conditions and trying new agents, hoping to make progress.
Looking at it now, the production is gradually refined, and the yield is also rising. This is not only my work, but also the result of the joint efforts of all colleagues. We hope that this product can be widely used in the pharmaceutical and material industries, contributing to the prosperity of the industry and promoting its long-term progress.
Toxicity Research
Today, there is a substance, named 1-Iodo-3, 5-Difluoro-4-Bromobenzene, in our chemical research, its toxicity research is very important. Looking at this substance, the structure is unique, containing iodine, fluorine, bromine and other elements. The combination of these elements may cause it to have special chemical properties, and it is also related to toxicity.
To study its toxicity, it is first necessary to look at its interaction with organisms. It enters the organism or reacts with key molecules of the cell, disturbing the normal physiology of the cell. Or damage the cell membrane, disrupt the exchange of substances inside and outside the cell; or affect the enzyme activity, hindering biochemical reactions.
Furthermore, consider its environmental toxicity. In the environment, this substance is difficult to degrade or accumulate. It may be transmitted through the food chain, endangering organisms at all levels.
Therefore, a detailed study of 1-Iodo-3, 5-Difluoro-4-Bromobenzene toxicity, is of great benefit to the protection of ecology and health. We must use rigorous methods to explore its toxicity mechanism and lay a solid foundation for prevention and control.
Future Prospects
In the future, at 1-Iodo-3, 5-Difluoro-4-Bromobenzene this thing, and in the field of chemical research, there must be a new expansion. I expect that the method of synthesis will be easy to achieve, and the energy consumption will be reduced and the rate of increase. And in many fields, such as research and development, it may be able to achieve its unique properties, forming the foundation of new technologies, curing diseases, and solving diseases. In the field of materials, or in the field of materials, such as increasing their performance and resistance, it is used for children and construction. This kind of vision is not a lie, but is based on the trend of chemical evolution and technological refinement. In the future, it will definitely be able to meet my expectations, so that this thing can be used in the world, and it will benefit the human world.
Where to Buy 1-Iodo-3,5-Difluoro-4-Bromobenzene in China?
As a trusted 1-Iodo-3,5-Difluoro-4-Bromobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Iodo-3,5-Difluoro-4-Bromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

1-Iodo-3, what is the main use of 5-Difluoro-4-Bromobenzene?
1-Iodine-3,5-difluoro-4-bromobenzene is a crucial chemical substance in the field of organic synthesis. Its main uses are widely found in many fields such as medicine, pesticides and materials science.
In the field of medicine, such compounds are often used as key intermediates for the synthesis of drug molecules with specific biological activities. Due to the unique electronic and spatial effects of halogen atoms in its structure, it can significantly affect the activity, selectivity and pharmacokinetic properties of drug molecules. For example, a new type of antibacterial drug constructed with the help of this compound can greatly improve its antibacterial activity, and at the same time exhibit a high degree of selectivity against specific bacteria, thereby reducing the toxic and side effects of the drug on human normal cells.
In the field of pesticides, 1-iodine-3,5-difluoro-4-bromobenzene also plays an indispensable role. Pesticides prepared from this raw material are often highly efficient, low-toxic and environmentally friendly. For example, synthetic new insecticides have excellent killing effects on a variety of pests, and are easy to degrade in the environment, greatly reducing the harm to the ecological environment.
In the field of materials science, this compound can be used to prepare functional materials with excellent performance. For example, in organic optoelectronic materials, the introduction of this compound structure can optimize the electrical and optical properties of the material, improve the charge transfer efficiency and luminous efficiency of the material, thus providing strong support for the development of organic Light Emitting Diode (OLED), organic solar cells and other optoelectronic devices.
In summary, 1-iodine-3,5-difluoro-4-bromobenzene has a wide range of application prospects in many important fields due to its unique chemical structure, and has made significant contributions to promoting technological progress and innovation in related fields.
1-Iodo-3, what are the physical properties of 5-Difluoro-4-Bromobenzene
1-Iodine-3,5-difluoro-4-bromobenzene is one of the organic compounds. Its physical properties are very important and are related to many chemical applications.
Looking at its properties, at room temperature, it is mostly colorless to light yellow liquid. This color characteristic can help chemists to distinguish it during preliminary observation. And it has a certain volatility and will slowly emit in the air.
When it comes to melting point, the melting point of 1-iodine-3,5-difluoro-4-bromobenzene is within a specific range, but the exact value depends on the experimental conditions. In general, its melting point is relatively low, which makes it easy to change from solid to liquid in a slightly warmer environment.
The boiling point is also a key physical property. Its boiling point also has a specific value. When this temperature is reached, the compound converts from liquid to gaseous. The level of boiling point is closely related to the intermolecular forces. The molecular structure of 1-iodine-3,5-difluoro-4-bromobenzene causes its boiling point to be in the corresponding range. Chemists can control the temperature to obtain pure products in separation operations such as distillation.
In terms of solubility, 1-iodine-3,5-difluoro-4-bromobenzene is insoluble in water because its molecular structure contains a large proportion of hydrophobic groups such as hydrocarbons. However, it exhibits good solubility in common organic solvents such as ethanol, ether, and dichloromethane. This property is of great significance in organic synthesis reactions. Chemists can choose suitable organic solvents to disperse the compounds uniformly in the reaction system to promote the smooth progress of the reaction.
Density is also a key consideration. The density of 1-iodine-3,5-difluoro-4-bromobenzene is higher than that of water. If mixed with water, it will sink to the bottom of the water. This density characteristic can provide chemists with a basis for material distribution in some separation and reaction processes, and help to rationally design experimental procedures.
1-Iodo-3, what are the synthesis methods of 5-Difluoro-4-Bromobenzene
The synthesis method of 1-iodine-3,5-difluoro-4-bromobenzene can be studied in the following ways.
First, the benzene derivative containing bromine and fluorine is used as the starting material. First, the derivative is reacted with an iodine substitution reagent under appropriate conditions. For example, potassium iodide and an appropriate oxidant are selected, and bromine or fluorine are replaced by iodine in an organic solvent at a suitable temperature and catalytic conditions to obtain the target product. This process requires fine regulation of the reaction temperature, the proportion of reagents and the reaction time. If the temperature is too high, side reactions may occur, resulting in a decrease in the purity of the product; if the ratio is improper, it will also affect the reaction yield.
Second, the Grignard reagent method can be used. The phenyl Grignard reagent containing bromine and fluorine is first prepared, and then it is reacted with the iodine-substituted reagent. When preparing Grignard reagent, the choice of solvent is very critical, and anhydrous ether or tetrahydrofuran is often a good choice to ensure that the reaction environment is anhydrous and oxygen-free, otherwise Grignard reagent is easy to decompose. During the reaction, control the dropwise addition speed and temperature, and slowly add the iodine-substituted reagent to make the reaction proceed smoothly, so as to avoid sudden violent reactions and affect the formation of products.
Third, the coupling reaction catalyzed by transition metals is used. For example, a palladium-catalyzed system is selected, and the benzene derivative containing bromine and fluorine and the iodine-substituted aromatic hydrocarbon are used as The type of ligand has a great influence on the reactivity and selectivity, and needs to be carefully screened. At the same time, the strength and dosage of alkali also need to be precisely controlled to optimize the reaction conditions and improve the yield and purity of 1-iodine-3,5-difluoro-4-bromobenzene.
1-Iodo-3, 5-Difluoro-4-Bromobenzene what are the precautions during storage and transportation
1-Iodine-3,5-difluoro-4-bromobenzene is an organic compound, and various precautions are essential during storage and transportation.
First storage, this compound should be stored in a cool, dry and well-ventilated place. It is sensitive to heat and moisture. If it is exposed to high temperature or humidity, it may cause decomposition and deterioration, which will damage its quality and purity. Therefore, choose a dry and suitable temperature storage to prevent accidents.
Furthermore, the storage place must be kept away from fire, heat sources, and must not be mixed with oxidants, strong alkalis and other substances. Because of its certain chemical activity, in case of oxidants or strong alkalis, it is easy to cause violent chemical reactions, resulting in fire, explosion and other risks. And should be stored in a sealed container to prevent it from contacting with air, prevent oxidation or moisture absorption.
As for transportation, it must act in accordance with relevant regulations and standards. Before transportation, ensure that the packaging is complete, tightly sealed, clearly marked, and its characteristics and hazard warnings. During transportation, avoid exposure to the sun and rain, control the speed and smooth driving, and avoid package damage due to bumps and collisions.
The means of transportation also need to be clean and dry, and there are no substances that may react with it. When loading and unloading, the operator should handle it with care, do not drop it, heavy pressure, and ensure the safety of the goods.
All of these are to be taken into account when storing and transporting 1-iodine-3,5-difluoro-4-bromobenzene, provided that these matters are followed to ensure its safety and smooth circulation.
1-Iodo-3, what is the market price of 5-Difluoro-4-Bromobenzene?
I look at this question and ask about the market price of 1-iodine-3,5-difluoro-4-bromobenzene. However, it is not easy to know its price. The price of this compound often changes due to many reasons.
First, the price of raw materials is the main factor. If the price of iodine, fluorine, bromine and other raw materials required for the synthesis of this compound fluctuates, the price of the finished product will also change. If the price of raw materials decreases, the price of this compound may decrease; conversely, if the price of raw materials increases due to scarcity, the price will rise.
Second, the difficulty of synthesis is related to the cost. If the method of synthesizing this compound is complicated, expensive reagents, special equipment are required, or energy consumption is huge, the production cost will be high, and the market price will be high. If a new simple and low-cost synthesis method is developed, the price may decline.
Third, the situation of market supply and demand also affects its price. If many industries have strong demand for this compound, but the supply is limited, the price will rise; if the demand is weak, and the output is too much, the price will fall.
Fourth, the price varies depending on the manufacturer. Well-known large factories may have slightly higher product prices due to their emphasis on quality; while small factories compete for the market, the price may be slightly lower.
However, we do not have the exact market price. For details, you can consult the chemical raw material supplier, or check it on the chemical product trading platform, or refer to the relevant industry reports, so that you can get a more accurate price.