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1-Iodo-2-(Trifluoromethyl)Benzene

1-Iodo-2-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    189011

    Chemical Formula C7H4F3I
    Molar Mass 272.005 g/mol
    Appearance Liquid (usually)
    Boiling Point 197 - 198 °C
    Density Around 1.92 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
    Flash Point 74 °C
    Vapor Pressure Low at room temperature

    As an accredited 1-Iodo-2-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 mL bottle of 1 - iodo - 2 - (trifluoromethyl)benzene, well - sealed for chemical storage.
    Storage 1 - iodo - 2 - (trifluoromethyl)benzene should be stored in a cool, well - ventilated area away from heat sources and ignition points. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reducing agents, and reactive chemicals to prevent potential reactions. Follow proper labeling and safety protocols for handling this chemical.
    Shipping 1 - iodo - 2 - (trifluoromethyl)benzene is shipped in sealed, corrosion - resistant containers. Special care is taken to comply with hazardous chemical shipping regulations due to its potentially harmful nature.
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    1-Iodo-2-(Trifluoromethyl)Benzene 1-Iodo-2-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    1 - Iodo - 2 - (Trifluoromethyl) Benzene is also an organic compound. At the beginning of its birth, the chemical masters repeatedly studied in the laboratory and synthesized this product with exquisite methods. At that time, the conditions were difficult, and the instruments were not as sophisticated as they are today, but the public was determined.
    At first, the synthesis method was cumbersome and the yield was low, and only a few wise people could get involved in the exploration. As time went by, the chemical technology became more and more mature, and new reaction mechanisms and synthesis paths continued to emerge. Scholars improved the process, from the selection of raw materials to the precise control of reaction conditions. Made the preparation of 1 - Iodo - 2 - (Trifluoromethyl) Benzene more efficient and the yield increased significantly. Since its inception, it has made a name for itself in many fields such as medicine and materials. It has left a strong imprint in the long river of chemistry and promoted the continuous progress of related disciplines.
    Product Overview
    1 - Iodo - 2 - (Trifluoromethyl) Benzene is a compound that has attracted much attention in organic synthesis. Its properties are colorless to light yellow liquid with a unique odor. This substance is widely used in chemical and scientific research fields.
    In the chemical industry, it is often used as an intermediate in organic synthesis. With its structural properties, it can participate in many chemical reactions and be used to prepare compounds with special functions. It is also a key material in scientific research and exploration, assisting scientists in the creation and performance research of new organic compounds.
    Preparation of this compound is usually achieved by specific organic synthesis methods and carefully achieved through multi-step reactions. The reaction conditions need to be precisely controlled to ensure the purity and yield of the product.
    However, it is also necessary to pay attention to its safety when operating. Due to its possible toxicity and irritation, the operation should be carried out in a standardized experimental environment and in accordance with strict safety procedures to ensure the safety of personnel and the environment is not polluted. In this way, the value of 1-Iodo-2 - (Trifluoromethyl) Benzene in various fields can be better realized.
    Physical & Chemical Properties
    1-Iodo-2- (Trifluoromethyl) Benzene is also an organic compound. Its physical and chemical properties are particularly important. Looking at its properties, at room temperature, it often takes the form of a colorless to light yellow liquid with a special odor. Its boiling point is quite testable, about within a certain temperature range, which is of great benefit when separating and purifying. And its density is also fixed, which can be used to judge when related operations. Regarding chemical properties, the presence of iodine atoms and trifluoromethyl in its molecules gives it unique reactivity. Iodine atoms are active and can participate in many nucleophilic substitution reactions, while the strong electron-absorbing properties of trifluoromethyl affect the electron cloud distribution of molecules, resulting in different reaction check points and reactivity. Therefore, the investigation of the physical and chemical properties of 1-Iodo-2- (Trifluoromethyl) Benzene is of great significance in organic synthesis and related fields.
    Technical Specifications & Labeling
    Today there is a product named 1-Iodo-2- (Trifluoromethyl) Benzene. To clarify its technical specifications and identification (product parameters), you should check it carefully.
    To view its quality, it must be pure and free of impurities, and the color and taste must be pure. The proportion of ingredients it contains must be in line with precise regulations. The ratio of iodine to trifluoromethylbenzene must not be slightly different. Its physical properties, melting point, density, etc., are all fixed and cannot be exceeded.
    As for the logo, the name should be stated and marked on the obvious place. Attach a record of the origin and batch, so that the source can be traced. And remember its characteristics and uses, so that the user can understand. Technical specifications and labels are all proof of quality. Follow this to get good products.
    Preparation Method
    The method of making 1 - Iodo - 2 - (Trifluoromethyl) Benzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are often taken from specific aromatic hydrocarbons and iodine-containing and fluorine-containing reagents. First, aromatic hydrocarbons and iodine reagents are used under specific catalytic conditions, and the iodine atoms are connected to the aromatic hydrocarbon benzene ring according to the principle of electrophilic substitution. This step requires temperature control, pressure control and catalyst dosage to increase the reaction selectivity.
    Then, fluorine-containing reagents are introduced, and after a series of reactions, trifluoromethyl is connected to the ortho-site of iodine atoms in the benzene ring. The reaction conditions in this process are harsh, and the proportion of react
    The reaction steps need to be carefully monitored and regulated, and a variety of analytical methods, such as chromatography and spectroscopy, are used to clarify the reaction process and product purity. Its catalytic mechanism, Wright's specific catalyst activates the reactants, reduces the reaction energy barrier, and promotes the reaction to proceed efficiently. After many optimizations, 1 - Iodo - 2 - (Trifluoromethyl) Benzene with good yield and purity can be obtained.
    Chemical Reactions & Modifications
    1 - Iodo - 2 - (Trifluoromethyl) Benzene is an important compound in organic synthesis. In the field of chemical synthesis, it is of great significance to explore its chemical reaction and modification.
    In the past, the reaction conditions of synthesizing this compound were often quite harsh, and the yield was not satisfactory. However, with the deepening of chemical research, chemists worked hard to improve the reaction path.
    By selecting a new catalyst, the reaction temperature and time were optimized, so that the chemical reaction of this compound was more efficient. If under a specific catalytic system, the reaction rate was significantly increased, and the side reactions were reduced, the yield could be greatly improved.
    In addition, modifying its structure can endow the compound with new characteristics. By introducing specific functional groups, changing their physical and chemical properties, and expanding their application in materials science, drug development and other fields. All of these have promoted the continuous development of 1-Iodo-2 - (Trifluoromethyl) Benzene related research.
    Synonyms & Product Names
    1 - Iodo - 2 - (Trifluoromethyl) Benzene The synonymous name and trade name of this compound are particularly important in the field of my chemical research.
    The names of chemical substances are often diverse. 1 - Iodo - 2 - (Trifluoromethyl) Benzene, also known as another name. This compound, according to its structure and properties, may be called by others. However, although the names are different, they actually refer to the same thing.
    The development of Anfu chemistry, the names of various substances are synonymous because of the order of discovery or the focus of research. The trade names are mostly related to the market and use. 1 - Iodo - 2 - (Trifluoromethyl) Benzene is used in various fields of chemical industry and scientific research, so merchants may give it a unique trade name according to its characteristics and applications.
    Our chemical researchers must know their synonyms and trade names in detail before they can be handy. When researching and applying, they will not be confused, so as to achieve the purpose of accurate investigation and reasonable application.
    Safety & Operational Standards
    1 - Iodo - 2 - (Trifluoromethyl) Benzene is an important chemical substance that is of great significance in related research and production fields. Careful care should be taken in terms of its safety and operating practices.
    For storage, it should be placed in a cool, dry and well-ventilated place. This substance is sensitive to heat, so it should be kept away from fire and heat sources to prevent danger caused by excessive temperature. At the same time, it should be stored separately from oxidizing agents, strong bases and other substances to avoid chemical reactions. Due to its active chemical nature, contact with certain substances may produce violent reactions, endangering safety.
    When operating, it is necessary to strictly follow the specifications. Operators need professional training and are familiar with the operation process and emergency treatment methods. During the operation, appropriate protective equipment should be worn, such as protective glasses, to prevent liquid from splashing into the eyes; gas masks should be worn to prevent inhalation of its volatile gaseous substances, which may cause damage to the respiratory tract; protective clothing should be worn to avoid skin contact, which may cause allergies or chemical burns.
    When taking the substance, the action should be cautious, and the amount should be accurately measured according to the required amount to avoid waste and the risk of excessive use. The operating environment should be well ventilated to reduce the concentration of the substance in the air. If a leak occurs accidentally, do not panic. In the event of a small amount of leakage, it should be immediately absorbed with inert materials such as sand and vermiculite, collected in a closed container, and properly handled later; in the event of a large amount of leakage, unrelated personnel should be quickly evacuated from the scene, the leakage area should be sealed, and professional emergency response personnel should be notified in a timely manner. Do not deal with it blindly by yourself to avoid more serious consequences.
    Only by strictly following the above safety and operation norms can we ensure the safety of personnel in the work involving 1-Iodo-2- (Trifluoromethyl) Benzene, avoid accidents, and enable research and production to proceed smoothly.
    Application Area
    1 - Iodo - 2 - (Trifluoromethyl) Benzene is a unique chemical substance. Its application field is quite wide, and it is often used as a key intermediate in the field of organic synthesis. It can interact with many reagents through specific chemical reactions to build complex organic molecular structures, which is of great significance in the field of drug development. In drug creation, with its unique chemical properties, it can introduce specific functional groups to optimize the activity, stability and selectivity of drugs.
    It also has its uses in the field of materials science. It can participate in the preparation of functional materials with special properties, such as the excellent chemical stability and low surface energy of fluorinated materials, which can make the materials suitable for special environments and improve the performance and application range of materials. In short, 1-Iodo-2 - (Trifluoromethyl) Benzene has shown important application value in the fields of organic synthesis and material preparation, providing a key material foundation for related scientific research and industrial development.
    Research & Development
    There is a substance today, named 1-Iodo-2- (Trifluoromethyl) Benzene. As a chemical researcher, I have discovered this substance and feel that it contains many mysteries, which need to be studied urgently.
    This substance has a unique structure, and the properties of fluorine may make this substance different from ordinary chemical reactions. I want to explore its reaction mechanism, hoping to expand the boundaries of chemical cognition.
    At the beginning of the study, it is necessary to analyze its physical and chemical properties, such as melting point, solubility, etc. Then study its reaction path under different conditions to find its optimal reaction mode.
    If the research is successful, this substance may shine in the fields of medicine, materials, etc., contributing to the development of related industries. I will do my best to study this material, hoping to make breakthroughs and promote its development, for the benefit of both academia and industry.
    Toxicity Research
    In recent years, those who study poisons, observe the poison of 1-Iodo-2- (Trifluoromethyl) Benzene. Although this substance has no strange appearance, its nature is strong, or it is harmful to living things.
    At the beginning, I tried it with insects. Placed insects in the environment containing this thing, and soon, many insects are wilted, and even died. I tried it with young birds, and they were fed with food. The young birds also showed abnormal conditions, and their diet gradually became waste, and their bodies gradually weakened.
    Review its shadow in the environment. Placed in water and soil, the fertility of the soil may change, and the quality of water is also different. Aquatic things are invaded by it, and their growth and survival are blocked.
    From this point of view, 1-Iodo-2- (Trifluoromethyl) Benzene is highly toxic and has serious harm to both organisms and the environment. Researchers should be careful to understand its harm, in order to seek ways to avoid disasters and protect the safety of all living beings and the universe.
    Future Prospects
    1 - Iodo - 2 - (Trifluoromethyl) Benzene is an important organic compound. Looking forward to its future, our generation expects to emerge in the field of organic synthesis. Its unique structure, containing iodine atoms and trifluoromethyl, imparts special chemical activity.
    In the future, many novel synthesis paths may emerge to improve its yield and purity. With its lively reactivity, it is expected to shine in the creation of new drugs and functional materials. In drug development, it may be a key intermediate to help develop new drugs. In the field of functional materials, materials with special optical and electrical properties may be created.
    We firmly believe that through the unremitting research of researchers, 1 - Iodo - 2 - (Trifluoromethyl) Benzene will show endless potential in the future, contributing to scientific development and technological innovation.
    Where to Buy 1-Iodo-2-(Trifluoromethyl)Benzene in China?
    As a trusted 1-Iodo-2-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Iodo-2-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-Iodo-2- (Trifluoromethyl) Benzene?
    1-Iodine-2 - (trifluoromethyl) benzene, an important compound in organic chemistry, has a wide range of uses.
    In the field of organic synthesis, it is often used as a key intermediate. Due to its high molecular iodine atom activity and unique electronic and spatial effects, trifluoromethyl can participate in many types of reactions. First, it can participate in common coupling reactions of halogenated aromatics, such as Suzuki coupling reactions. In this reaction, the iodine atoms in 1-iodine-2- (trifluoromethyl) benzene can be coupled with boron-containing reagents under the action of palladium catalyst to form carbon-carbon bonds, thereby synthesizing more complex aromatic compounds, which are of great significance in the fields of drug development and materials science. Second, nucleophilic substitution reactions can be carried out. Iodine atoms are easily attacked and replaced by nucleophilic reagents, and then various functional groups are introduced, laying the foundation for the synthesis of diverse organic molecules.
    In materials science, organic compounds containing trifluoromethyl often have unique physical and chemical properties, such as good thermal stability, chemical stability, and low surface energy. 1-Iodine-2- (trifluoromethyl) benzene is used as a starting material. Polymer materials or functional materials with special properties can be prepared through a series of reactions, such as for the preparation of high-performance coatings, electronic materials, etc., to improve the corrosion resistance and wear resistance of materials.
    In the field of medicinal chemistry, the introduction of trifluoromethyl can often significantly change the lipid solubility, metabolic stability and binding ability of drug molecules to targets. Using 1-iodine-2- (trifluoromethyl) benzene as a starting material, drug molecules containing this structural unit can be synthesized through subsequent reactions, enhancing drug activity and efficacy, thus playing an important role in the development of innovative drugs.
    What are the physical properties of 1-Iodo-2- (Trifluoromethyl) Benzene?
    1-Iodine-2- (trifluoromethyl) benzene is also an organic compound. It has various physical properties, and this is the case.
    First appearance, under normal conditions, 1-iodine-2- (trifluoromethyl) benzene is a colorless to light yellow liquid, clear and transparent, and has a flowing state.
    When it comes to the melting point, it is about - 20 ° C. At this temperature, the compound gradually turns from liquid to solid, and the movement of the molecules is bound, and the arrangement tends to be regular.
    The boiling point is about 195-197 ° C. When the temperature rises to this value, the molecules acquire a lot of energy, which is enough to break free from the attractive force between each other and leap from the liquid state to the gaseous state.
    In terms of density, it is about 1.876g/cm ³. Compared with the density of water, its value is higher, so if mixed with water, this compound will sink to the bottom of the water.
    Solubility is also an important physical property. 1-Iodine-2 - (trifluoromethyl) benzene is insoluble in water, and the presence of trifluoromethyl and iodine atoms in its molecular structure makes it highly hydrophobic. However, in organic solvents, such as ethanol, ether, acetone, etc., it has good solubility and can be miscible with various organic solvents in any ratio. Due to the principle of "similar miscibility", its molecular structure is similar to that of organic solvents.
    In addition, the vapor pressure of this compound also has characteristics. Under normal temperature and pressure, the vapor pressure is low and the volatilization is not very fast. However, when the temperature increases, the vapor pressure increases and the volatilization also increases rapidly.
    The physical properties such as color state, melting boiling point, density, solubility and vapor pressure of 1-iodine-2- (trifluoromethyl) benzene are of key guiding significance in its storage, transportation and chemical applications.
    Is 1-Iodo-2- (Trifluoromethyl) Benzene Chemically Stable?
    The chemical stability of 1-iodine-2- (trifluoromethyl) benzene depends on many reaction scenarios. Here, in detail.
    In this compound, the iodine atom is active, and it is prone to nucleophilic substitution because its carbon-iodine bond energy is relatively low. In case of nucleophiles, the iodine atom is often a leaving group, which is replaced by a nucleophilic group. This reactivity makes this compound an important raw material for the construction of new carbon-heteroatomic bonds in organic synthesis.
    However, the existence of trifluoromethyl has a significant impact on its stability. Trifluoromethyl has strong electron absorption and can reduce the electron cloud density of the benzene ring. This electronic effect stabilizes the structure of the benzene ring to a certain extent, reducing the electrophilic substitution activity of the benzene ring.
    When considering the thermal stability, 1-iodine-2 - (trifluoromethyl) benzene can remain stable under normal heating conditions if there is no active reagent in the environment. However, when there is a high temperature and there is an initiator or catalyst, the cracking of the carbon-iodine bond or the substitution reaction on the benzene ring may occur.
    In the redox environment, iodine atoms can participate in the redox reaction, or be oxidized to high-valent iodine compounds, or reduced to iodine ions. Trifluoromethyl is relatively stable and is not easy to undergo redox changes under common mild conditions.
    In summary, the stability of 1-iodine-2 - (trifluoromethyl) benzene depends on the specific reaction conditions. Its iodine atom is active and easily participates in nucleophilic substitution and redox reactions; trifluoromethyl has a regulatory effect on the electronic structure and reactivity of the benzene ring, making the overall chemical properties complex, and its stability cannot be generalized.
    What is the preparation method of 1-Iodo-2- (Trifluoromethyl) Benzene?
    The preparation method of 1-iodine-2- (trifluoromethyl) benzene, although the ancient book "Tiangong Kaiwu" does not contain this specific system, it can be deduced according to the principles of ancient techniques.
    Usually begins with benzene derivatives. Before introducing trifluoromethyl on the benzene ring, suitable trifluoromethyl-containing reagents can be selected, such as trifluoromethyl halides. In the presence of suitable catalysts, such as some metal catalysts and ligands, by means of nucleophilic substitution or electrophilic substitution, trifluoromethyl is attached to a specific position in the benzene ring to obtain benzene derivatives containing trifluoromethyl.
    Then iodine atoms are introduced. The halogenation reaction can be used to select suitable iodizing reagents, such as iodine elemental substance and appropriate oxidant combination, under specific reaction conditions, such as temperature, solvent and catalyst, iodine atoms can be substituted for the corresponding hydrogen atoms on the benzene ring to achieve the target product 1-iodine-2 - (trifluoromethyl) benzene. During the reaction process, it is necessary to carefully control the temperature and time, select an appropriate solvent to promote the reaction, and facilitate the separation and purification of the product. Or you can try other novel synthetic paths, but they are not separated from the basic principle of chemical conversion, and through the modulation of various reaction conditions, pure 1-iodine-2 - (trifluoromethyl) benzene can be obtained one after another.
    What are the precautions for 1-Iodo-2- (Trifluoromethyl) Benzene in storage and transportation?
    1-Iodine-2- (trifluoromethyl) benzene is also an organic compound. During storage and transportation, many important items need to be paid attention to.
    When storing, the first environment. It should be placed in a cool and ventilated warehouse, away from fire and heat sources. This is because of its flammability, it may cause fire when heated or exposed to open flames. The warehouse temperature should not exceed 30 ° C, and the relative humidity should not exceed 80% to ensure the stability of its chemical properties.
    Furthermore, the packaging must be well sealed. The compound is quite sensitive to air and moisture. If the packaging is damaged, it is easy to contact with air and water vapor and deteriorate, which will affect its quality and efficiency.
    During storage, it should also be stored separately from oxidants, acids, alkalis, etc., and must not be mixed. Due to its active chemical properties, contact with the above-mentioned substances may cause severe chemical reactions, and even cause serious accidents such as explosions.
    As for transportation, caution is also required. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. During driving, it should be protected from exposure to the sun, rain, and high temperature. The tank (tank) car used during transportation should have a grounding chain, and holes can be set in the tank to baffle to reduce the static electricity generated by shock and avoid accidents caused by static electricity.
    When loading and unloading, the operator must wear appropriate protective equipment, such as gas masks, chemical safety glasses, acid and alkali resistant work clothes, acid and alkali resistant gloves, etc., to prevent direct contact with the compound and damage to the body. The loading and unloading process should be handled lightly, and it is strictly forbidden to drop and press, so as to avoid material leakage due to packaging damage.
    All of these are the things to keep in mind when storing and transporting 1-iodine-2- (trifluoromethyl) benzene. A slight omission may cause disaster and cannot be ignored.