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1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene

1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene

Hongda Chemical

Specifications

HS Code

438562

Chemical Formula C6H3BrClFI
Molecular Weight 329.35
Appearance Solid (Typical description for such organic halide compounds, exact appearance may vary)
Solubility In Water Low (Organic halides are generally hydrophobic)
Solubility In Organic Solvents Good solubility in common organic solvents like dichloromethane, chloroform (Typical for aromatic halides)
Vapor Pressure Low (due to its relatively high molecular weight and non - volatile nature)
Stability Stable under normal conditions, but can react with strong nucleophiles or reducing agents

As an accredited 1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - iodo - 2 - fluoro - 4 - chloro - 6 - bromobenzene packaged in a sealed glass bottle.
Storage 1 - iodo - 2 - fluoro - 4 - chloro - 6 - bromobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent leakage and exposure to air or moisture. Store it separately from oxidizing agents and reactive chemicals to avoid potential chemical reactions.
Shipping 1 - iodo - 2 - fluoro - 4 - chloro - 6 - bromobenzene is shipped in sealed, corrosion - resistant containers. It's transported with proper labeling, following strict regulations for hazardous chemicals, ensuring safe transit to the destination.
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1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene 1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene
General Information
Historical Development
1 - Iodo - 2 - Fluoro - 4 - Chloro - 6 - Bromobenzene is also a chemical substance. Looking at the historical development of this substance, the chemists of the past have moved forward step by step on the road of material exploration. At first, only a little knowledge of the properties of halobenzene, after countless studies, dissected the structure and explored its reaction mechanism.
At that time, the chemical skills were not exquisite, and it was difficult to obtain this 1 - Iodo - 2 - Fluoro - 4 - Chloro - 6 - Bromobenzene. However, the ancestors made unremitting efforts to improve the synthesis method, from simple steps to orderly and exquisite.
After years of precipitation, the deeper the understanding of it, the more mature the synthesis method. Today, this substance is widely used in the fields of medicine and materials. Looking at its history, it is a witness to the development of chemistry. The past has been painstakingly explored, and it has finally become a convenient path for the present, laying a solid foundation for future scientific research.
Product Overview
1 - Iodo - 2 - Fluoro - 4 - Chloro - 6 - Bromobenzene is a unique compound. It has a unique chemical structure, with four halogen atoms of iodine, fluorine, chlorine and bromine arranged in sequence on the benzene ring.
The physical properties of this compound may have a specific melting point, and in common organic solvents, the solubility has its own laws. In terms of chemical properties, the presence of halogen atoms gives it active reactivity.
Due to the characteristics of halogen atoms, it can participate in many organic reactions. For example, in nucleophilic substitution reactions, halogen atoms can be replaced by other nucleophiles, and then a variety of organic compounds can be derived, providing rich raw materials and possibilities for the field of organic synthetic chemistry. In the research and development of organic materials or the exploration of medicinal chemistry, 1 - Iodo - 2 - Fluoro - 4 - Chloro - 6 - Bromobenzene has potential application value, which can lay an important foundation for the creation of new materials and specific drugs.
Physical & Chemical Properties
1 - Iodo - 2 - Fluoro - 4 - Chloro - 6 - Bromobenzene is a special organic compound. The physical and chemical properties of this compound are quite important to scholars. Its appearance is often specific, or crystalline, and its color is different, which is related to its molecular arrangement and structure.
In terms of physical properties, the melting point and boiling point have specific values, which are determined by the intermolecular forces. The types and positions of halogen atoms in the molecule make their polarity different, which in turn affects the melting and boiling point.
Chemically, due to the activity of halogen atoms, it can involve a variety of reactions. Iodine atoms are relatively active, or can be replaced under suitable conditions to participate in nucleophilic substitution reactions. Fluorine, chlorine, and bromine atoms also affect the reactivity and selectivity of compounds due to their electron cloud distribution.
Scholars study this compound, hoping to clarify its properties, open up new avenues for organic synthesis, materials science and other fields, and develop its potential in many aspects.
Technical Specifications & Labeling
Today there is a thing called 1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene. Its process specifications and identification (product parameters) should be studied in detail by our generation.
Looking at this compound, its synthesis process needs to follow strict procedures. The selection of raw materials must be carefully selected to ensure that the purity is up to standard. The reaction conditions are also critical, and the temperature, pressure, and catalyst dosage all need to be precisely controlled. If the reaction temperature, or needs to be maintained in a specific range, if it is too high, the side reactions will be raw, and if it is too low, the reaction will be slow.
As for the identification, the product parameters must be clear and clear. From the element content to the physical and chemical properties, it should be carefully marked. In this way, the user can understand it without the risk of misuse. This is all essential for process specifications and labeling, and is relevant to product quality.
Preparation Method
To 1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene this substance, it is necessary to study the method in detail. Prepare the raw materials first, take an appropriate amount of aromatic hydrocarbons containing chlorine, bromine and fluorine, and co-place them with iodine substitutes. The reaction steps are to slowly stir at a suitable temperature to make the aromatic hydrocarbons and iodine substitutes blend, and electrophilic substitution occurs. The temperature is controlled in a certain range to prevent side reactions.
After the reaction is completed, it is separated and purified. By column chromatography, the filler is selected and the filler is adapted, and the specific eluent is rinsed to obtain a pure product. After recrystallization, the solvent is selected, the coarse product is dissolved, the temperature is cooled and crystallized, and the filter and dryness are filtered to obtain the refined product.
During this process, the reaction device is provided with temperature control and a And it is operated in a well-ventilated place to prevent the accumulation of harmful substances. In this way, high-quality 1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene can be obtained.
Chemical Reactions & Modifications
Yu is dedicated to the research of chemical products, and recently focused on the compound 1 - Iodo - 2 - Fluoro - 4 - Chloro - 6 - Bromobenzene. Chemical reactions and modifications are the core of our research.
In the investigation of the reaction of 1 - Iodo - 2 - Fluoro - 4 - Chloro - 6 - Bromobenzene, it is observed that its interaction with various reagents can cause different chemical changes. The activity of halogen atoms in its structure affects the process and product of the reaction. Either nucleophilic substitution or free radical reaction depends on the reaction conditions and the added reagents.
Modification is intended to optimize its properties. Or introduce new groups to change its physical and chemical properties, with better applications in materials science, drug development and other fields. Such as adjusting the reaction temperature and solvent, the reaction selectivity can be changed to obtain the desired modified products. This is the essence of chemical research, and unremitting exploration can lead to new areas of achievement.
Synonyms & Product Names
Today there is a thing called 1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene. This is a product of chemistry and is useful in various fields.
Concept its name, which is composed of a combination of halogen atoms, iodine, fluorine, chlorine, bromine and benzene ring are connected, and the structure is unique. Its synonymous names also vary depending on industry, region or habit. In order to recognize its characteristics, merchants may give it a different trade name, aiming to attract attention and promote its circulation.
In the academic world, it is mostly matched by a standardized scientific name to clarify its exact structure and nature. However, in the community, in order to facilitate memory and dissemination, the trade name may be more popular and easy to remember. This is all to make this thing better known and play its due effect. In this way, the synonymous name and the trade name, although expressed differently, refer to this unique chemical product.
Safety & Operational Standards
1 - Iodo - 2 - Fluoro - 4 - Chloro - 6 - Bromobenzene is an important chemical substance that plays a key role in the field of chemical research and production. It is necessary to discuss in detail the safety and operation of this substance.
In terms of safety, the first to bear the brunt is the potential harm caused by its chemical properties. This compound contains iodine, fluorine, chlorine, bromine and other halogen atoms, some of which are toxic and corrosive. If it comes into contact with the skin accidentally, it may cause skin burns, allergies and other symptoms. Therefore, when operating, you must wear protective clothing and gloves to prevent skin contact. If you accidentally splash on the skin, you should immediately rinse with a large amount of water and seek medical treatment in time.
In addition, its volatile gaseous substances may cause irritation to the respiratory tract. In the operating environment, it is necessary to ensure good ventilation, and it is best to carry out relevant operations in the fume hood. If you accidentally inhale, or cause respiratory discomfort such as cough and asthma, you should quickly move to a fresh air place and seek medical assistance if necessary.
In terms of operating standards, the weighing process needs to be rigorous and accurate. Due to its special nature, small differences in measurement or huge deviations in experimental results. Use accurate weighing instruments and operate strictly according to operating procedures.
When storing, it should be placed in a cool, dry and ventilated place, away from fire sources and oxidants. Because its structure contains a variety of halogen atoms, it may react violently or even cause an explosion when heated, open flame or oxidant.
When using this compound in a chemical reaction, the reaction conditions need to be precisely controlled. Temperature, pH and other factors may affect the reaction process and product purity. Before the experiment, the relevant reaction mechanism and conditions should be carefully understood, and the experimental steps should be carefully planned.
In conclusion, although 1 - Iodo - 2 - Fluoro - 4 - Chloro - 6 - Bromobenzene is an important substance in chemical research, its safety and operating standards should not be underestimated. Only by strictly following the relevant guidelines can we ensure the safe and smooth operation of the experiment and avoid accidents.
Application Area
1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene this substance, it is useful in many fields. In the field of pharmaceutical research and development, it can be used as a key intermediate to help synthesize special agents, or to treat difficult diseases. In the field of material science, it can participate in the creation of new functional materials, making materials have unique optoelectronic properties, or used in advanced electronic devices. In the field of organic synthesis, its special structure can lead to a variety of chemical reactions, paving the way for the synthesis of complex organic molecules. Therefore, its application range is wide and the potential is huge, just like a treasure hidden in a box, waiting for researchers to explore in depth, in order to develop its more wonderful functions, and contribute to the progress of various fields.
Research & Development
In recent years, I have specialized in the field of halogenated aromatics 1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene this compound. At the beginning, analyzing its molecular structure, exploring the wonder of the bonding of each atom, knowing its spatial arrangement, and revealing the source of its chemical properties.
Then, study the synthesis method. After many attempts, trying different reaction conditions, adjusting the temperature, pressure, and catalyst. At first, the yield was not as expected, and there were many impurities. However, I was not discouraged, I carefully observed the reaction process, checked the literature, and consulted colleagues, and finally obtained the optimization path. With a specific catalyst, the temperature is controlled in a certain range, and the yield gradually rises, and the purity is also good.
Today, this compound has emerged in the fields of medicine and materials. I hope it can expand its application and contribute to scientific research and industry. I also hope that future studies can continue my career and explore in depth, so that its potential can be fully developed and it will bloom in the path of science.
Toxicity Research
Today, there is a 1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene, which is very important for my chemical research. It is urgent to study its toxicity.
Looking at the composition of this substance, iodine, fluorine, chlorine, and bromine all have characteristics. Past studies have focused on its chemical properties, but toxicity studies are still lacking.
Due to its special structure, the action path of this substance in organisms is complex and difficult to detect. It is unknown whether it interferes with cell metabolism or affects gene expression. Although there is no detailed literature to prove its exact toxicity, the chemical reason is that such halogenated aromatics are often potentially harmful.
I will use rigorous methods to investigate their toxicity from the cellular level and animal experiments. Hope to be able to understand its harm, provide conclusive evidence for future application and protection, so as to avoid its harm and make use of it, so that chemical research can benefit the world.
Future Prospects
The vision of the future is the heart of our researchers. Today, there are 1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene this thing, and it can be used in the field of transformation.

It can be used to create special effects, saving life and pain.

It can also be used in the field of material science to explore new frontiers.
Our researchers will do our best to explore the secrets of this thing, so that it can be used in the future, for the benefit of the world, and for the achievement of the best, and the possibility of development.
Where to Buy 1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene in China?
As a trusted 1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene?
1-Iodine-2-fluoro-4-chloro-6-bromobenzene is a compound that has attracted much attention in the field of organic synthetic chemistry. Its main use can probably be found in the field of organic synthesis.
First, in the field of pharmaceutical chemistry, this compound may serve as a key intermediate. Drug development often requires the construction of molecules with specific structures and activities. The diverse halogen atoms of 1-iodine-2-fluoro-4-chloro-6-bromobenzene can introduce various functional groups through many organic reactions, such as nucleophilic substitution reactions, and then build complex molecular structures that fit drug targets. Taking the development of anti-cancer drugs as an example, it may be possible to use this intermediate to create new drug molecules with specific inhibitory effects on cancer cells through delicate reaction design.
Second, in the field of materials science, it also has potential uses. The development of organic electronic materials is on the rise, and halogenated aromatics are often the cornerstone of high-performance organic semiconductor materials. 1-Iodine-2-fluoro-4-chloro-6-bromobenzene can be reacted with other conjugated systems to form materials with unique electrical and optical properties, or can be applied to the manufacture of organic Light Emitting Diodes (OLEDs), organic field effect transistors (OFETs) and other devices to improve their performance.
Third, this compound may also play a role in pesticide chemistry. The creation of pesticides requires precise design of molecular structures to achieve high-efficiency insecticidal and weeding effects. 1-Iodine-2-fluoro-4-chloro-6-bromobenzene can be used as a starting material and chemically modified to synthesize pesticide products with high selectivity and activity to specific pests or weeds, which can help agricultural production of pest control.
In short, 1-iodine-2-fluoro-4-chloro-6-bromobenzene has potential uses in many fields such as drugs, materials, and pesticides, providing important support for the development of organic synthetic chemistry and the progress of related industries.
What are the physical properties of 1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene?
1-Iodine-2-fluoro-4-chloro-6-bromobenzene is an organohalogenated aromatic hydrocarbon compound. Its physical properties are quite elusive.
First of all, its appearance, under room temperature and pressure, is mostly colorless to light yellow liquid, but it also depends on its purity. If it contains impurities, or a slightly darker color. Looking at its smell, it often has a special smell unique to aromatic hydrocarbons. Although it is not a bad smell, it also has a distinct smell.
When it comes to boiling point, due to the large number of halogen atoms in the molecule, the intermolecular force increases, resulting in a high boiling point. It is approximately between 250 and 300 degrees Celsius, and the specific value will vary slightly depending on the measurement environment and method. This higher boiling point is due to the increase in molecular polarity of halogen atoms and the enhancement of intermolecular van der Waals forces.
In terms of melting point, the melting point of this compound is about -10 ° C to 10 ° C, which is relatively low. This is because the molecular structure contains halogen atoms, but the planar structure of the benzene ring and the distribution of halogen atoms do not make the molecules closely arranged to form a strong lattice energy, so the melting point does not reach a very high degree.
In terms of solubility, the substance is insoluble in water, because water is a polar solvent, and although 1-iodine-2-fluorine-4-chloro-6-bromobenzene contains a slightly polar halogen atom, the non-polar part of the benzene ring dominates, resulting in a large difference in polarity from water. According to the principle of "similar miscibility", it is difficult to dissolve in water. However, in organic solvents such as dichloromethane, chloroform, ether, etc., it has good solubility, because these organic solvents are similar to the polarity of the compound.
The density is heavier than that of water, usually between 2.0 and 2.2 g/cm ³. The relative weight of halogen atoms is relatively large, resulting in an increase in molecular weight, while the molecular volume is not excessive expansion, so the density is higher than that of water.
Its vapor pressure is low, and it is difficult for molecules to escape from the liquid surface due to strong intermolecular forces. This characteristic also affects its volatilization rate in the environment. For volatile organic compounds, volatilization is slower.
In summary, the physical properties of 1-iodine-2-fluoro-4-chloro-6-bromobenzene are different from those of common organic compounds due to the interaction of benzene ring and halogen atoms in the molecular structure.
Is 1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene chemically stable?
1-Iodine-2-fluoro-4-chloro-6-bromobenzene, the stability of its chemical properties is related to the interaction and bond energy of atoms in the molecule. This compound contains iodine, fluorine, chlorine, and bromine halogen atoms on the benzene ring.
The benzene ring has a conjugated π electron system, which is quite stable. However, the introduction of halogen atoms changes the distribution of electron clouds due to different electronegativity. Fluorine atoms are extremely electronegative and have a strong attraction to the electron cloud of the benzene ring, which decreases the electron cloud density of the benzene ring and changes the reactivity. The electronegativity of chlorine and bromine is slightly weaker than that of fluorine, but it also affects the distribution of electron clouds
Although the electronegativity of the iodine atom is relatively small, its atomic radius is large, and the spatial steric resistance effect is significant. The combined action of various halogen atoms affects the stability of the compound. When encountering electrophilic reagents, the electron cloud density of the benzene ring decreases, and the electrophilic substitution reaction is more difficult than that of benzene. However, under certain conditions, halogen atoms can participate in reactions such as nucleophilic substitution, resulting in structural changes and impaired stability.
In addition, its stability is also influenced by external conditions. Under high temperatures, the thermal motion of molecules intensifies, the vibration of chemical bonds increases, and it is easy to cause bond breakage and reduce stability. When exposed to light, molecules absorb light energy, and electrons transition, triggering chemical reactions and impairing their stability. < br Polar solvents can interact with compounds to change their electron cloud distribution, which in turn affects their stability. Therefore, the stability of 1-iodine-2-fluoro-4-chloro-6-bromobenzene is not absolute, but it maintains a dynamic equilibrium under the combined action of many factors.
What are 1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene synthesis methods?
The synthesis of 1-iodine-2-fluoro-4-chloro-6-bromobenzene is an important topic in organic synthetic chemistry. There are various synthesis routes, and the following are common methods.
One is the halogenation reaction method. First, benzene can be used as the starting material, and halogen atoms such as fluorine, chlorine, bromine, and iodine can be gradually introduced through halogenation. For example, benzene and chlorine can be obtained under the action of an appropriate catalyst, such as ferric chloride. Then, chlorobenzene reacts with bromine under specific conditions, and bromine atoms can be introduced at specific positions in the benzene ring. Then, through fluorination reaction, fluorine atoms are introduced with suitable fluorine substitutes, such as potassium fluoride, in appropriate solvents and reaction conditions. Finally, the introduction of iodine atoms is achieved through iodine substitution reaction, using iodine elemental substances and suitable oxidizing agents. This process requires precise control of reaction conditions, such as temperature, reaction time, and proportion of reactants, to ensure the selectivity and yield of each step of the reaction.
Second, the reaction of aryl diazonium salts is used. First, aniline compounds are formed into aryl diazonium salts by diazotization reaction, and then fluorine, chlorine, bromine, and iodine atoms are introduced by Sandmeier reaction or other similar reactions with different cuprous halides and other reagents. This method can precisely control the position of the substituents, but the diazotization reaction requires strict control of the reaction conditions to avoid the decomposition of diazonium salts, and the selection and use of reagents are also crucial.
Third, the coupling reaction catalyzed by transition metals. Using aromatic halides containing different halogens as raw materials, with the help of transition metal catalysts, such as palladium catalysts, in the presence of ligands and bases, the coupling reaction occurs. Through rational design of reaction substrates and selection of appropriate reaction conditions, the synthesis of the target product can be achieved. This method has the advantages of high efficiency and good selectivity, but the catalyst cost is high, and the reaction system is relatively complex, so the reaction conditions need to be carefully optimized.
When synthesizing 1-iodine-2-fluoro-4-chloro-6-bromobenzene, the advantages and disadvantages of each method should be comprehensively considered. According to the actual situation, such as the availability of raw materials, cost, reaction equipment and other factors, the most suitable synthesis method should be selected to achieve the purpose of efficient, economical and environmentally friendly synthesis.
What is the price range of 1-Iodo-2-Fluoro-4-Chloro-6-Bromobenzene in the market?
I haven't seen 1 - Iodo - 2 - Fluoro - 4 - Chloro - 6 - Bromobenzene in the market, but if you want to know its price, you can look at it from many places.
The price of materials in the market often varies depending on the purity of quality, quantity, supply and demand, and different producers. If you want to get the exact price of this product, first, you can visit the platform for trading chemical raw materials. Such platforms often collect the prices of various merchants, or you can get an approximate price range. Second, ask chemical raw material suppliers, who often give real-time prices according to market conditions and goods.
However, this compound contains iodine, fluorine, chlorine, bromine and other halogen atoms, and it is difficult to synthesize, so its price is not cheap. Probably due to the difficulty of preparation, special methods and reagents are required, resulting in higher costs. If its purity is high and the dosage is sufficient, its price per gram may be from tens of yuan to more than 100 yuan; if the amount is small, and high purity is required, the price may be even higher, or more than 100 yuan per gram. However, these are all words, and the actual price is still subject to inquiries in the market. You must visit the market in person and ask the merchants before you can get the exact price.