1-Hydroxy-4-Ethoxy-2,3-Difluorobenzene

Hongda Chemical

Specifications

HS Code	180137
Chemical Formula	C8H8F2O2
Molar Mass	174.144 g/mol

As an accredited 1-Hydroxy-4-Ethoxy-2,3-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	1 - hydroxy - 4 - ethoxy - 2,3 - difluorobenzene packaged in 1 - kg bottles.
Storage	1 - Hydroxy - 4 - ethoxy - 2,3 - difluorobenzene should be stored in a cool, dry, and well - ventilated area, away from heat sources and open flames to prevent potential ignition. Keep it in a tightly sealed container to avoid contact with air and moisture, which could cause degradation. Store it separately from incompatible substances, like oxidizing agents, to prevent chemical reactions.
Shipping	1 - Hydroxy - 4 - ethoxy - 2,3 - difluorobenzene is shipped in properly labeled, sealed containers. Compliance with chemical transport regulations ensures safe transit, safeguarding against spills and environmental exposure during shipping.

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General Information

Historical Development

1 - Hydroxy - 4 - Ethoxy - 2,3 - Difluorobenzene is also a new product of chemical engineering. Its research and development process can be improved. The past, the person of chemical engineering, the study of physical properties, the exploration and exploration of. At the beginning, the characteristics of this compound were reviewed briefly. However, people are committed to research, day and night. Or change the original product, or different raw materials, reverse the product, and improve the production rate. The method is obtained, which is conducive to anti-step, rate improvement, etc. From the initial ignorance, to today, the synthesis of this product can be confirmed, which is one of the important achievements on the way to research. This process, the work of no one person, is the work of many researchers, and it also adds a good quality to the exhibition.

Product Overview

1 - Hydroxy - 4 - Ethoxy - 2,3 - Difluorobenzene is a unique compound. Its properties are unique, with hydroxy, ethoxy and difluorine atoms, which are cleverly arranged on the benzene ring. This structure endows it with specific physical and chemical properties.
In terms of physical properties, it may have a specific melting and boiling point, and its solubility or different from the usual class. Chemically, the reactivity of hydroxyl groups may lead to reactions such as nucleophilic substitution, ethoxy groups affect its electron cloud distribution, and difluorine atoms enhance its stability and chemical inertness.
Synthesis of this compound requires fine study of the reaction path. Or use benzene derivatives to precisely construct its structure through various reactions such as halogenation, etherification, and hydroxylation. However, each step of the reaction requires careful control of conditions, such as temperature and catalyst, to ensure the high efficiency and selectivity of the reaction. This compound has potential applications in medicine, materials, and other fields, and it is worth exploring its properties and application prospects.

Physical & Chemical Properties

1 - Hydroxy - 4 - Ethoxy - 2,3 - Difluorobenzene is a unique compound. Its physicochemical properties are crucial. Looking at its physical properties, at room temperature, this substance may be in a specific state, solid, or liquid, and needs to be inspected in detail. Its color and odor are also key characteristics, which can be initially identified by the senses. As for its chemical properties, the presence of hydroxyl groups, ethoxy groups, and difluorine atoms in its molecular structure gives it unique reactivity. Hydroxyl groups can participate in many reactions, such as esterification, and combine with acids to form different ester products. Ethoxy groups also affect their stability and reaction tendency. Because of its electronegativity, difluorine atoms make molecular electron clouds different, or cause nucleophilic and electrophilic reactions. Precise exploration of its physical and chemical properties can pave a solid foundation for its applications in chemical, pharmaceutical and other fields.

Technical Specifications & Labeling

1 - Hydroxy - 4 - Ethoxy - 2,3 - Difluorobenzene is a special chemical product. Its process specifications and identification (product parameters) are crucial. To make this product, it is necessary to follow a precise process. The selection of raw materials must be well-done and the proportions should be accurate. During the reaction process, temperature, pressure and other conditions must be strictly controlled, and a slight error will affect the purity and quality of the product. Its identification should clearly mark various parameters, such as composition ratio, purity grade, scope of application, etc., so that users can clearly understand its characteristics and uses, and use it safely in accordance with the specifications to ensure that it can play an appropriate role in industrial production and other fields.

Preparation Method

To make 1 - Hydroxy - 4 - Ethoxy - 2,3 - Difluorobenzene, the method of making it is the first raw material and the production process. Choose pure raw materials and mix them according to the delicate ratio. The reaction step is to first make the raw materials react in a certain way, control the temperature to a suitable degree, be punctual and accurate, so that they can be fully combined. The catalytic mechanism is also necessary. Select the appropriate catalyst to increase the reaction rate and extract the amount of product. After this step, the product may be obtained. During the operation, it is necessary to be rigorous and meticulous, and follow scientific rules to produce excellent 1 - Hydroxy - 4 - Ethoxy - 2,3 - Difluorobenzene.

Chemical Reactions & Modifications

1 - Hydroxy - 4 - Ethoxy - 2,3 - Difluorobenzene is an important chemical product. The research on its chemical reaction and modification has attracted the attention of the academic community.
In the past, the preparation of this product often encountered the dilemma of complicated reactions and low yield. Many reaction conditions are harsh, resulting in high cost and low efficiency. In order to solve this problem, we dedicated ourselves to the study and in-depth exploration of the reaction mechanism.
After repeated experiments, it was found that adjusting the reaction temperature and catalyst type can significantly optimize the reaction. Moderately increase the temperature to speed up the reaction rate; the introduction of specific new catalysts can precisely regulate the reaction path and improve the purity of the product.
In this way, through the improvement of chemical reaction conditions, the preparation process of 1-Hydroxy-4-Ethoxy-2,3-Difluorobenzene has been revolutionized, and the yield and quality have been improved, paving the way for its wide application.

Synonyms & Product Names

1 - Hydroxy - 4 - Ethoxy - 2,3 - Difluorobenzene, which is very important in my chemical research. Its synonym and trade name also have some exquisite research.
Looking at the words of various sages in the past, each of these chemical substances has its own name. Although its essence is one, the different names also reflect the changes in academia and the progress of cognition at that time.
There are those who call it [specific synonym 1], and the study at that time was called Chang, because of the focus of research at that time and the limitations of cognition. There are also those who call it [specific synonym 2]. The name of this name may be related to the method used at that time and the nature of the observation. As for the trade name, there was also [specific trade name] in the past, which was designed to respond to the market, so that it could be easily known in the middle of business.
Today, although the understanding is gradually deepening, looking back at the name of the past, we can still know the context of academic development, and it also adds a lot of information for my generation of researchers to think about.

Safety & Operational Standards

1 - Hydroxy - 4 - Ethoxy - 2,3 - Difluorobenzene Safety and Operation Code
For 1 - Hydroxy - 4 - Ethoxy - 2,3 - Difluorobenzene, the product of the chemical is also, its safety and operation standards are essential and cannot be ignored.
When storing, it must be placed in a cool, dry and well ventilated place. Keep away from fire and heat sources to prevent accidents. Due to its nature, it may be lively, and it is dangerous to be exposed to heat or open flames, so caution must be taken.
When operating, strictly abide by the procedures. The operator must be specially trained and familiar with the essentials. Wear appropriate protective equipment, such as protective gloves, goggles, etc., to protect your own safety. The operating environment should be well ventilated to avoid the accumulation of harmful gases.
If you accidentally come into contact with this object, you must know the emergency method. If it touches the skin, rinse quickly with a large amount of flowing water, and then seek medical attention as appropriate. If it enters the eyes, you should also rinse with a large amount of water immediately, and seek medical attention if necessary.
Dispose of the waste of this object must also follow the norms. It should not be discarded at will, and it should be properly disposed of in accordance with relevant laws and regulations to avoid polluting the environment and harming all parties.
In short, the safety and operating standards of 1 - Hydroxy - 4 - Ethoxy - 2,3 - Difluorobenzene are related to personal safety and environmental safety. They should be kept in mind and practiced without slack.

Application Area

1 - Hydroxy - 4 - Ethoxy - 2,3 - Difluorobenzene is a unique chemical substance. Its application field is quite considerable. In the field of pharmaceutical research and development, it can be used as a key intermediate to help create new specific drugs, which is expected to overcome many difficult diseases and bring good news to patients. In the field of materials science, its unique chemical structure may endow materials with novel properties, such as optimizing the light transmittance and stability of optical materials, or improving the conductivity and insulation properties of electronic materials, so that materials can be used in high-tech industries. Furthermore, in the field of fine chemicals, it can be used as a raw material to synthesize high-end fine chemicals to meet the strict needs of high-end manufacturing industries for special chemicals, and promote related industries to a higher level. It has significant application potential in multiple key fields, serving as a key to opening the door to innovation and development in many fields.

Research & Development

In recent years, in the field of chemistry, 1 - Hydroxy - 4 - Ethoxy - 2,3 - Difluorobenzene has gradually become more and more important to us. Our generation has devoted themselves to studying it, hoping that it can have extraordinary development in various applications.
At the beginning, it was very difficult to obtain this pure thing. All kinds of synthetic methods are either complicated or ineffective. However, we worked tirelessly and repeatedly, and finally obtained exquisite methods, which can make high-purity products.
Looking at its properties, it shows unique activity in specific reactions, and seems to hold endless potential. We are also thinking about its application. If it is used in medicine, it may help to create new drugs; if it is used in materials, it may add new and peculiar properties.
Although it has been achieved today, there is still a long way to go. We should continue to be diligent and dig deep into its potential. In the future, we can make this compound shine in the way of scientific research and application, and contribute to the development of chemistry.

Toxicity Research

The industry of chemical industry is related to people's livelihood and safety. Today there is a thing called 1-Hydroxy-4-Ethoxy-2,3-Difluorobenzene, and we should study its toxicity in detail.
The toxicity study of this thing is an important task for the chemical industry. Look at its molecular structure, the genus of fluorine atoms, or hidden dangers. Fluoride is active, easy to phase with other things, or cause toxic changes.
Taste it with all kinds of creatures and observe its physiological changes. In rats, feed a small amount and observe their diet and behavior. The rat is seen to be tired, eating less and less, or because of toxic invasion of the body, disturbing its viscera.
And in the plant, fill it with the liquid containing this substance to observe its growth state. See the leaves have a withered yellow color, growth is sluggish, and the toxicity hurts its vitality.
To sum up, 1-Hydroxy-4-Ethoxy-2,3-Difluorobenzene is toxic and harmful to all living beings. Follow-up should be careful, study its methods to avoid harm, protect the benefits of chemical industry, and avoid its harm.

Future Prospects

I have dedicated myself to studying 1 - Hydroxy - 4 - Ethoxy - 2,3 - Difluorobenzene. Its unique nature is quite latent in the field of chemical industry. Although the current research is still in the preliminary stage, I am full of enthusiasm for the future development.
Looking at the current state of my husband, although the preparation method still needs to be refined, the yield is not ideal. However, I am convinced that with the wisdom and diligence of all researchers, we will be able to find a way to optimize it. In the future, its application may be expanded, and it will shine in the fields of medicine and materials.
In the field of medicine, it may provide a key foundation for the research of new drugs, helping human beings to cure diseases and strengthen their bodies; in the world of materials, it may endow materials with novelty and create a new quality. I look forward to waiting for this material to bloom in the future, be used by the world, and become a boost to scientific and technological progress, creating a new chapter in human well-being.

Where to Buy 1-Hydroxy-4-Ethoxy-2,3-Difluorobenzene in China?

As a trusted 1-Hydroxy-4-Ethoxy-2,3-Difluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 1-Hydroxy-4-Ethoxy-2,3-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

1-Hydroxy-4-Ethoxy-2, what are the main application fields of 3-Difluorobenzene

1-Hydroxy-4-ethoxy-2,3-difluorobenzene is one of the organic compounds. Its main application fields are related to both medical chemistry and materials science.
In the field of pharmaceutical chemistry, such compounds are often key intermediates for the synthesis of new drugs. Due to their special chemical structure, fluorine atoms and ethoxy groups can endow the prepared drugs with unique physical, chemical and biological activities. The introduction of fluorine atoms can significantly change the lipid solubility, metabolic stability and bioavailability of drug molecules. And the presence of hydroxyl groups can enhance the interaction between drugs and biological targets, which helps to improve the efficacy and selectivity of drugs. Therefore, it is often used in the development of antibacterial, anti-inflammatory, anti-tumor and other drugs.
As for the field of materials science, 1-hydroxy-4-ethoxy-2,3-difluorobenzene is also useful. It can be used as a monomer or additive for the preparation of high-performance polymer materials. By polymerizing with other monomers, its unique structural properties can be integrated into polymer materials. The resulting materials may have excellent thermal stability, chemical stability and mechanical properties, and can be used to manufacture electronic devices, optical materials, coatings, etc. In the manufacture of electronic devices, such materials may exhibit excellent insulating and dielectric properties; in optical materials, they may affect the refractive index and light transmittance of materials; in the field of coatings, they may enhance the wear resistance and corrosion resistance of coatings.
From this perspective, although 1-hydroxy-4-ethoxy-2,3-difluorobenzene is a small molecule compound, it plays a significant role in the two important fields of pharmaceutical chemistry and materials science, and is of crucial significance to promoting technological development and innovation in related fields.

1-Hydroxy-4-Ethoxy-2, what are the physical properties of 3-Difluorobenzene?

1-Hydroxy-4-ethoxy-2,3-difluorobenzene is one of the organic compounds. Its physical properties are unique and valuable for investigation.
Looking at its properties, under normal circumstances, it is mostly a colorless to light yellow liquid, and this color state is a significant feature of its appearance. Its smell often has a special aroma, but this fragrance is not rich and pungent, but has a unique charm, or can trigger a different perception of smell in some specific scenes.
When it comes to the melting point, the melting point is relatively low, and it is difficult to appear solid at common ambient temperatures; while the boiling point varies depending on specific conditions and is roughly within a certain range. This characteristic makes it follow a specific law during heating or cooling, providing a basic basis for its application in various processes.
In terms of solubility, it shows good solubility in organic solvents. Common organic solvents such as ethanol and ether can be fused with it to form a uniform mixed system. However, in water, its solubility is quite limited, which is determined by its molecular structure characteristics. The characteristics of organic groups in the molecule make the force between them and water molecules weak, so it is difficult to dissolve in water. The density of
is also one of its important physical properties. Compared with common organic solvents or related compounds, its density has a specific value. This value is related to its distribution in the mixed system. It is of great significance in the fields of chemical production, experimental operation, etc., for precise control of reaction conditions, separation and purification of products, etc.
The physical properties of 1-hydroxy-4-ethoxy-2,3-difluorobenzene, whether it is the color and odor of the appearance, the melting point, solubility and density, are all related to each other, and together build up its unique physical properties, laying a solid foundation for its application in many fields such as organic synthesis and materials science.

1-Hydroxy-4-Ethoxy-2, what are the synthesis methods of 3-Difluorobenzene

The synthesis of 1-hydroxy-4-ethoxy-2,3-difluorobenzene is an important topic in the field of organic synthesis. There are many ways to synthesize it, and each has its own advantages and disadvantages. It needs to be carefully selected according to the specific situation.
First, it can be obtained by the reduction reaction of 2,3-difluoro-4-ethoxybenzoic acid. In this path, a suitable reducing agent is usually selected, such as lithium aluminum hydride. First dissolve 2,3-difluoro-4-ethoxybenzoic acid in a suitable organic solvent, such as anhydrous ether or tetrahydrofuran. Under the condition of low temperature and stirring, lithium aluminum hydride is slowly added, and the reaction needs to be maintained for a certain period of time, during which the reaction process should be closely monitored. The key to this reaction lies in the precise control of the reaction temperature, the amount of reducing agent and the reaction time. If it is not properly controlled, it is easy to cause side reactions to occur, affecting the purity and yield of the product.
Second, with 2,3-difluorophenol as the starting material, it first etherifies with ethanol under the action of an acidic catalyst to generate 2,3-difluorophenethyl ether. Then, through a specific oxidation method, a hydroxyl group is introduced into the benzene ring. During the etherification reaction, the commonly used acidic catalysts include concentrated sulfuric acid or p-toluenesulfonic acid. During the reaction process, attention should be paid to the reaction temperature should not be too high to The subsequent oxidation steps can be selected with suitable oxidizing agents, such as potassium permanganate or manganese dioxide, etc., depending on the specific reaction conditions and requirements. This method has relatively many steps, and each step requires fine operation to ensure the quality and yield of the product in each step, so as to finally obtain the target product 1-hydroxy-4-ethoxy-2,3-difluorobenzene.
Third, it can also be achieved by the nucleophilic substitution reaction of halogenated aromatics. Select suitable halogenated benzene derivatives, such as 2,3-difluoro-4-halogenated phenyl ether, and react with the nucleophilic reagent containing hydroxyl groups in the presence of an appropriate base. Commonly used bases are potassium carbonate, sodium carbonate, etc. The reaction needs to be carried out in a suitable solvent, such as N, N-dimethylformamide (DMF) or dimethyl sulfoxide (DMSO). This method requires a lot of selection of halogenated benzene derivatives and optimization of reaction conditions. Factors such as the activity of halogen atoms, the basicity of nucleophiles, and the polarity of solvents will all have a significant impact on the rate and selectivity of the reaction.
All these synthesis methods have advantages and disadvantages. In the actual synthesis process, it is necessary to comprehensively consider many factors such as the availability of raw materials, cost, difficulty of reaction conditions, and the purity and yield of the product, and carefully select the most suitable synthesis path to prepare 1-hydroxy-4-ethoxy-2,3-difluorobenzene efficiently and with high quality.

1-Hydroxy-4-Ethoxy-2, what is the price range of 3-Difluorobenzene in the market?

1-Hydroxy-4-ethoxy-2,3-difluorobenzene is in the market, and its price range is not easy to break directly. This compound is a raw material in the field of fine chemicals, and its price often changes due to multiple reasons.
First, the supply and demand situation is the main reason for the price. If there are many people who want it, and the supply is small, the price will rise; if the supply exceeds the demand, the price may decline. For example, when the pharmaceutical industry has a large increase in demand for it, and the manufacturer has not expanded production, its price will rise.
Second, the price of raw materials is also loud. The preparation of this compound requires specific raw materials. If the price of raw materials increases, the cost will increase and the price will also increase. If the special fluoride raw materials required for preparation are damaged due to the origin, the supply shortage will skyrocket, and the price of 1-hydroxy-4-ethoxy-2,3-difluorobenzene will also rise.
Third, the complexity of the process is related to the cost. If the preparation process is complicated, high-end equipment and special technology are required, and the cost is high, the price will also be high. On the contrary, the process is simple, the cost will decrease, and the price may be low.
Fourth, the state of market competition has a great impact. There are many manufacturers and fierce competition, and the price may be reduced accordingly; if the market is monopolized, the price is often high.
Due to the ever-changing market conditions, it is difficult to determine the range of its price. For details, you can consult chemical raw material suppliers, industry experts, or refer to recent market transaction data to obtain a more accurate price.

1-Hydroxy-4-Ethoxy-2, what are the main manufacturers of 3-Difluorobenzene

1-Hydroxy-4-ethoxy-2,3-difluorobenzene is also an organic compound. There are many manufacturers, distributed in all aspects of the chemical industry.
In China, there are many manufacturers involved in the production of this compound. There are manufacturers specializing in the field of fine chemicals, who are involved in the manufacture of this product with their deep technical accumulation and advanced production technology. They focus on research and development to improve the purity and quality of products and emerge in the market competition.
There are also many manufacturers overseas. In Europe and the United States, there are chemical giants involved in this field. They have strong technical strength and excellent production equipment, and occupy an important position in the global chemical market. It produces this compound, either to meet the needs of the downstream of its own industrial chain, or to supply the global market.
Other small and medium-sized manufacturers, although they are not as large as large manufacturers, have also gained a share of the production of this compound by virtue of their flexible business strategies and deep cultivation of specific markets. Or focus on specific customer groups, or focus on developing unique applications, and find opportunities for survival and development in the market segment.
All these manufacturers are all in the production of 1-hydroxy-4-ethoxy-2,3-difluorobenzene. Together, they promote the circulation and application of this compound in the chemical market.