1-Fluoro-4-(Trifluoromethyl)Benzene

Hongda Chemical

Specifications

HS Code	516678
Chemical Formula	C7H4F4
Molecular Weight	164.10
Appearance	Colorless liquid
Odor	Characteristic
Boiling Point	102 - 104 °C
Melting Point	-46 °C
Density	1.29 g/cm³
Solubility In Water	Insoluble
Vapor Pressure	12 mmHg (20 °C)
Flash Point	12 °C

As an accredited 1-Fluoro-4-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	1 - fluoro - 4 - (trifluoromethyl)benzene, 500 mL in sealed, labeled chemical - resistant bottle.
Storage	1 - fluoro - 4 - (trifluoromethyl)benzene should be stored in a cool, well - ventilated area away from heat sources and open flames. It should be in a tightly sealed container to prevent leakage. Keep it separated from oxidizing agents and reactive substances. Store in a dedicated chemical storage facility following safety regulations to minimize the risk of fire, explosion, or harmful exposure.
Shipping	1 - fluoro - 4 - (trifluoromethyl)benzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring proper handling, storage, and transport to prevent leaks and safety risks.

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General Information

Historical Development

1 - Fluoro - 4 - (Trifluoromethyl) Benzene is also an organic compound. Its historical evolution is worth exploring. In the past, chemists studied the way of organic synthesis diligently. At first, the understanding of such fluorinated aromatic compounds was still shallow. However, with the passage of time, science and technology have gradually advanced. Chemists have made many breakthroughs in reaction mechanisms and synthesis paths with their wisdom and unremitting experiments.
In the early days, the synthesis of this compound was difficult, the conditions were harsh, and the yield was also low. After many scholars improved the method, from the selection of raw materials to the precise regulation of reaction conditions, step by step. If the exploration of catalysts, finding suitable ones makes the reaction more efficient. After years of precipitation, the synthesis technology has become more and more mature, and now the preparation of 1-Fluoro-4- (Trifluoromethyl) Benzene is more convenient, and it is widely used in many fields such as medicine and materials. This is a testament to the development of chemistry.

Product Overview

1 - Fluoro - 4 - (Trifluoromethyl) Benzene is also an organic compound. Its color is clear and transparent, and it has a special odor. This substance has a wide range of uses in the chemical industry and is often the key raw material for the synthesis of many fine chemicals.
Looking at its molecular structure, on the benzene ring, the fluorine atom is opposite to the trifluoromethyl group, giving it unique chemical properties. Because of its fluorine-containing group, it has high chemical stability and hydrophobicity.
In the process of synthesis, it can be prepared through a variety of chemical pathways. Usually, a specific halogenated aromatic hydrocarbon is used as the starting material, and fluorine atoms and trifluoromethyl are introduced through reactions such as nucleophilic substitution to obtain this compound. Due to its unique properties, it can be used as a pharmaceutical intermediate in pharmaceutical chemistry to assist in the development of new drugs with special curative effects. In the field of materials science, it can also contribute to the preparation of high-performance materials and enhance the chemical resistance and stability of materials.

Physical & Chemical Properties

1 - Fluoro - 4 - (Trifluoromethyl) Benzene is an organic compound. Its physical properties are colorless liquid at room temperature and pressure, with a special odor. The boiling point is about 102 - 104 ° C, the density is about 1.32 g/cm ³, insoluble in water, soluble in most organic solvents.
In terms of its chemical properties, due to the presence of fluorine atoms and trifluoromethyl, the chemical activity is unique. The benzene ring is affected by fluorine atoms and trifluoromethyl, the electron cloud density distribution changes, and the electrophilic substitution reaction activity is different. Trifluoromethyl has strong electron absorption, which reduces the electron cloud density of the benzene ring, making the electrophilic substitution reaction more difficult than benzene, and the substituents mainly enter the meta-site. This compound is often used as an intermediate in the field of organic synthesis, participating in many organic reactions to build complex organic molecular structures.

Technical Specifications & Labeling

1 - Fluoro - 4 - (Trifluoromethyl) Benzene is an important chemical substance. Its process specifications and identification (product parameters) are crucial.
Process specifications should specify the preparation steps, such as the selection of raw materials, must be pure and meet specific standards. Reaction conditions, such as temperature, pressure, and catalyst use, must be precisely controlled. Changes in temperature or reaction rate, pressure can also affect the purity of the product.
In terms of identification (product parameters), its physical properties, such as melting point, boiling point, density, etc., should be clearly marked for users to identify. Chemical properties should also be clearly stated, such as stability, reactivity, etc., so that operators know their characteristics in different environments. Only in this way can we ensure the safe and efficient application of this product in the chemical industry and other fields.

Preparation Method

This product of 1 - Fluoro - 4 - (Trifluoromethyl) Benzene should be made with refined raw materials and exquisite production technology. First, all kinds of raw materials need to be prepared, screened and purified, so that they are pure and free of impurities.
The production process first makes the relevant reactants mix in a suitable reactor according to a specific ratio. Control with precise temperature and pressure, according to the established reaction steps, step by step. In the initial stage, slow down the temperature, wait for the reactants to blend and stabilize, and gradually adjust the parameters to promote their full reaction.
During the reaction process, closely monitor and fine-tune according to real-time conditions. After the reaction is completed, the product is separated and purified to remove impurities. After a special catalytic mechanism, the quality of the product was optimized to obtain pure 1-Fluoro-4- (Trifluoromethyl) Benzene to meet the needs of all parties.

Chemical Reactions & Modifications

Wen Fujin has the name 1 - Fluoro - 4 - (Trifluoromethyl) Benzene. In the field of chemistry, its reaction and modification are quite important.
The chemical reaction of this substance is related to many mechanisms. The structure of its fluorine atom and trifluoromethyl gives it a unique activity. Or in the nucleophilic substitution reaction, the reaction path is different due to the electronegativity of fluorine. However, the initial reaction conditions may be insufficient, such as temperature and solvent selection, which are not optimal, and the reaction efficiency is not ideal.
As for modification, different functional groups can be introduced to change its physical and chemical properties. Or the hydroxyl group, amino group, etc. on the benzene ring can be increased to adjust its activity and use by electronic effect. However, the modification process also encounters problems, such as poor selectivity, which often leads to a cluster of side reactions and disturbance of product purity.
To improve its reaction and modification, it is necessary to study the reaction mechanism, fine-tune the conditions, and explore new methods to achieve better results, so as to develop the potential of this chemical in various fields.

Synonyms & Product Names

1 - Fluoro - 4 - (Trifluoromethyl) Benzene This product, its synonym and trade name, is also of great importance to our chemical researchers.
Covers the field of chemistry, there are more than one product, often due to different uses, production methods, and origins. 1 - Fluoro - 4 - (Trifluoromethyl) Benzene, or those named for its characteristics, take its fluorine-containing and trifluoromethyl structural characteristics, and get various nicknames. Or because of the convenience of business, in order to be easy to remember and easy to pass on, it has a unique product name.
When I study this product, I must carefully examine its synonym and trade name, so as not to confuse it. This is of great benefit to the accuracy of the experiment and the accuracy of the communication. Or in the classics, or in various reports, see its synonyms and trade names, when you know that they all refer to this 1-Fluoro-4- (Trifluoromethyl) Benzene, so that you can study chemistry, unimpeded, and explore the mystery.

Safety & Operational Standards

1 - Fluoro - 4 - (Trifluoromethyl) Benzene is also a chemical substance. Its safe production and operation specifications are of great significance and cannot be ignored.
To make this thing, the first thing to do is to place it in the factory, when it is well ventilated, to dissipate harmful gases. All utensils must be intact to prevent leakage. When preparing, the craftsman uses protective equipment, such as masks and gloves, to protect his body, skin, mouth and nose, and avoid direct contact with the substance.
There are also regulations for the storage of materials. It should be placed in a cool and dry place, away from fire and heat sources. And it should not be stored with mutually exclusive objects to prevent accidental changes. When handling, it is advisable to move slowly and handle it with care to avoid collision and damage to the package.
When operating, follow precise steps and follow established procedures. The temperature and pressure of the reaction should be closely monitored, and there may be a slight error or an accident. In case of emergencies, such as leaks, do not panic, and quickly initiate emergency measures. Evacuate everyone, prohibit fireworks, and then choose the appropriate way to dispose of according to the state of leakage.
After use, the remaining items should not be discarded at will. When recycled according to regulations, properly dispose of them to avoid polluting the environment. As for the utensils, they must be cleaned and inspected to prepare for next use.
In this way, it is possible to ensure the safety of the preparation and use of 1-Fluoro-4 - (Trifluoromethyl) Benzene, and the operation is in accordance with the norms.

Application Area

1 - Fluoro - 4 - (Trifluoromethyl) Benzene is an organic compound with a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize a variety of specific drugs, or to exert unique curative effects on specific diseases. In the field of materials science, it can participate in the creation of high-performance materials, giving materials special properties such as excellent corrosion resistance and thermal stability. In the fine chemical industry, it is also indispensable, providing important raw materials for the preparation of high-end fine chemicals. With its unique chemical structure, this compound has shown key value in many fields, constantly promoting the progress and innovation of related industries, just like the smart "ink", painting a brilliant chapter on the "picture scroll" of application.

Research & Development

In recent years, in the field of organic chemistry, 1 - Fluoro - 4 - (Trifluoromethyl) Benzene has gradually become more and more important to researchers. We first analyze its structure, explore its physicochemical properties, and understand its molecular structure. It is exquisite and its properties under normal conditions.
Then study its synthesis method, and try various ways, or improve the old method, or create a new way. Despite many obstacles, but unremitting research, hoping to obtain an efficient and pure synthesis path.
Furthermore, consider its application direction. In the fields of medicine and materials, its potential is seen. In medicine, it may be a key raw material for the creation of new agents; in materials, it helps to develop substances with specific properties.
Our researchers should persevere, explore its unfinished secrets, and promote its wider application, so as to achieve the progress of research and development, and make every effort for the prosperity of chemistry.

Toxicity Research

Today, there is a thing named 1 - Fluoro - 4 - (Trifluoromethyl) Benzene. In my chemical research, the study of its toxicity is of paramount importance. The nature of this thing is related to the safety of the user and the tranquility of the environment.
Detect its quality, explore its response to its surroundings, and explain its entry into the body, either by breathing, or by skin touch, or by eating. Investigate its changes in the body, observe its impact on the function of the organs, observe the damage of cells, and analyze the changes in genes.
And examine its state of dispersion in the environment, observe its transformation in water, soil, and air, and examine its impact on the ecological chain. Ji Neng is fully aware of the signs of its toxicity, and sets up comprehensive methods for using this material to avoid harm and profit, and to ensure human safety and ecological balance.

Future Prospects

Today, there is a product named 1 - Fluoro - 4 - (Trifluoromethyl) Benzene. Looking at its properties, it has specific properties and may have extraordinary uses in various fields of chemical industry.
Thinking about the future development, one is in the creation of materials, or it can assist in the research of new polymers. With its uniqueness, the material has better weather resistance, chemical resistance and other properties, adding new materials for aviation, construction and other industries. Second, in pharmaceutical research and development, it may become a key intermediate, helping to produce special drugs, treat difficult diseases, and solve the suffering of patients.
Although the road ahead is uncertain, with the heart of our researchers, we are determined to explore, hoping to expand its use, develop its path, and create a new environment for future generations, so that this material will shine brightly and benefit all people when it is not developed.

Where to Buy 1-Fluoro-4-(Trifluoromethyl)Benzene in China?

As a trusted 1-Fluoro-4-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 1-Fluoro-4-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-fluoro-4- (trifluoromethyl) benzene?

1-% Jiang-4- (Sanjiang methyl) benzene is also an organic compound. There are three main users of it.
First, in the field of organic synthesis, it is a key raw material. It has a unique structure and contains specific groups, which can be derived from various organic compounds through various chemical reactions. Chemists often rely on this to prepare substances with special properties and uses, such as fine chemicals, pharmaceutical intermediates, etc. Taking the synthesis of a certain type of anti-cancer drug as an example, 1-% Jiang-4- (Sanjiang methyl) benzene can be used as a starting material and converted into key fragments of drug molecules through several delicate reactions, thus achieving effective anti-cancer drugs.
Second, it also has important functions in materials science. Due to its stable chemical properties and certain physical properties, it can participate in the preparation of high-performance materials. If used in the preparation of special polymer materials, it can endow the material with excellent heat resistance and chemical corrosion resistance. These materials can be used in high-end fields such as aerospace, electronics and electrical appliances. Some components of aerospace vehicles need to withstand extreme temperatures and chemical environments. Materials containing 1-% Jiang-4- (Sanjiang methyl) benzene can just meet these needs and ensure the safe and stable operation of spacecraft.
Third, it also plays a role in the fragrance industry. It has a unique smell and can be formulated into a fragrance ingredient. The perfumer uses its special scent to cleverly match with other fragrances to create a complex and charming aroma. In the formula of high-end perfumes, a small amount of 1-% Jiang-4- (Sanjiang methyl) benzene can add a unique flavor to the perfume, making it more durable and layered, enhancing the quality and style of the perfume.

What are the physical properties of 1-fluoro-4- (trifluoromethyl) benzene?

In the case of 1-% meta-4- (tri-methyl) naphthalene, the physical properties of the substance are specific.
First of all, its shape is often crystalline, and the ground is smooth. The crystal surface is flat and smooth, and it can shine under light, just like a treasure carved by nature.
Until the degree of melting, the melting is specific, and the melting begins at a certain degree of precision. This is due to the arrangement of the molecular force. The boiling is also fixed, reflecting the energy required for the molecule to break free from the liquid phase beam.
Furthermore, its solubility, in the usual solution, such as ethanol and ether, has a certain solubility. However, when it dissolves in water, it does not match the molecular properties of the water molecules, and the properties of the water molecules do not match, and the properties of the water molecules are weak. According to the principle of similar miscibility, it dissolves in water.
In addition, the density is also its important physical properties. Its density is different from that of water. When placed in water, it can be determined by its sedimentation and floating. From this, it can also be known that its water density is high. And this object has a certain degree of certainty. In a normal environment, its chemical properties are peaceful, and it is not easy to combine with the surrounding objects. In case of specific chemical properties, or under special conditions, it can also be used for chemical reactions. This physical property can be changed.

Is 1-fluoro-4- (trifluoromethyl) benzene chemically stable?

The chemical properties of 1-% hydrocarbon-4- (trihydrocarbon methyl) naphthalene are still stable. In this compound, the structure of naphthalene has a certain stability, and its aromatic ring system has a conjugated π electronic system, which reduces the molecular energy and stabilizes the structure. The introduction of trihydrocarbon methyl at the 4th position of naphthalene, and the hydrocarbon group is the power supply group, can have an impact on the electron cloud distribution of the naphthalene ring, but in general, this effect does not break the stable structure of its conjugated system.
From the perspective of spatial structure, although trihydrocarbon methyl slightly increases the steric resistance of the molecule, it does not cause strong tension or instability in the molecule. In the general chemical environment, if there are no extreme conditions such as strong oxidants, strong acids, and strong bases, the carbon-carbon bonds and carbon-hydrogen bonds can be maintained relatively stable. In the case of mild reagents, the chemical reactivity is mostly limited to the activity check point of naphthalene rings, such as electrophilic substitution reactions, and the core structure of 1-% hydrocarbon-4- (trihydrocarbon methyl) naphthalene can still be retained during the reaction.
Even under the action of common external factors such as heating and light, without special reagents or conditions, this compound is not prone to spontaneous violent decomposition or rearrangement reactions. Its chemical stability may be of great significance in the fields of organic synthesis, materials science, etc. It can provide a stable basic structural unit for related research and applications, and is also conducive to further chemical modification and functionalization research using it as a starting material, without having to worry too much about its structure changing easily during general operation.

What are the preparation methods of 1-fluoro-4- (trifluoromethyl) benzene?

In order to prepare 1-alkane-4-trialkyl-benzene, the ancient method is as follows:
First, prepare its raw materials. Take the appropriate alkane and choose the appropriate carbon number, which is related to the structure and properties of the product. In addition, it is necessary to obtain the benzene derivative containing trialkyl methyl and find its purity to ensure the smooth reaction.
In the kettle, adjust the temperature to an appropriate degree. According to the ancient method, the temperature in the kettle is often slowed down with a charcoal fire, so that the temperature in the kettle can rise steadily and cannot be suddenly changed, causing the reaction to be disordered. The control of temperature is related to the reaction rate and the purity of the product, so be careful.
Add the raw material to the kettle according to a certain ratio. If the proportion is not correct, the product will be impure, or the reaction will be difficult. After throwing, stir slowly with a pestle to make the raw materials mix evenly. The speed of stirring is also particular. If the speed is fast, the raw materials will splash out, and if the speed is slow, the mixing will be uneven.
Wait for the reaction, during which you need to constantly observe the changes in the kettle. Observe its color, smell its gas, and know the progress of the reaction. The ancient method has no precision instrument today. It is all based on the eyes, nose, and smell. This is the experience of the ancient craftsmen for many years.
After the reaction is completed, take the product from the kettle. Filter its residue with a lustrous tool, leaving its clear liquid. Then use the method of distillation to purify the product. In the distiller, the temperature is adjusted to vaporize the product, and it is re-condensed into a liquid to obtain pure 1-alkane-4- (trialkyl methyl) benzene.
The preparation of this medicine requires the craftsman to be meticulous, and every step must not be ignored. From the selection of raw materials, to the control of temperature, ratio, stirring, and even the purification method, it is all about the quality of the medicine. Although the ancient method was not as convenient as today, the wisdom contained in it can also be used as a lesson for today.

What are the precautions for storing and transporting 1-fluoro-4- (trifluoromethyl) benzene?

For 1-% ether-4- (triether methyl) naphthalene, many matters should be paid attention to during storage and transportation. This compound has special properties and is related to the safety and quality of storage and transportation. It must not be taken lightly.
First storage environment. When looking for a cool, dry and well-ventilated place. Because it is afraid of moisture or moisture, it is easy to cause chemical reactions in case of moisture, resulting in quality damage. If placed in a humid place, water vapor may interact with the compound, causing its structure to change and affecting its inherent characteristics. And the temperature also needs to be carefully controlled. Excessive temperature may cause its volatilization to intensify, or even cause decomposition reactions, which will only increase safety hazards; too low temperature may change the morphology of the compound and affect subsequent use.
Times and packaging materials. Suitable packaging materials must be used to ensure its tightness. Commonly used glass or special plastic containers can not only prevent leakage, but also avoid chemical reactions with packaging materials. If the packaging material is not selected properly, it may cause the compound to spill, pollute the environment, and threaten the safety of personnel.
When transporting, it is crucial to handle it properly. This compound may have certain sensitivity, rough handling, strong vibration or collision may trigger dangerous reactions. The transportation vehicle should also be selected to drive smoothly, and the temperature and humidity conditions inside the vehicle are controllable.
Furthermore, the logo must be clear. On the storage container and transportation packaging, the name of the compound, characteristics, hazard warnings and other information should be prominently marked. In this way, the relevant personnel can be identified at a glance, and during the handling and handling process, they can take appropriate protective measures according to their characteristics to prevent accidents.
During the whole process of storage and transportation of 1-% ether-4- (triether methyl) naphthalene, personnel training is also indispensable. Make relevant practitioners fully aware of the characteristics, risks and emergency response methods of the compound. In this way, storage and transportation are safe and secure, and disasters are avoided.