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1-Fluoro-4-(Trichloromethyl)Benzene

1-Fluoro-4-(Trichloromethyl)Benzene

Hongda Chemical

Specifications

HS Code

297158

Chemical Formula C7H4Cl3F
Molar Mass 215.46 g/mol
Appearance Colorless to light - yellow liquid
Boiling Point Around 204 - 206 °C
Density Approx. 1.48 - 1.52 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Vapor Pressure Low at room temperature
Flash Point Around 85 - 90 °C
Odor Characteristic aromatic odor

As an accredited 1-Fluoro-4-(Trichloromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - fluoro - 4 - (trichloromethyl)benzene: 500g in a sealed, corrosion - resistant chemical - grade bottle.
Storage 1 - fluoro - 4 - (trichloromethyl)benzene should be stored in a cool, well - ventilated area, away from heat and ignition sources. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials like stainless steel or certain plastics. Store it separately from incompatible substances such as oxidizing agents and bases to prevent potential reactions.
Shipping 1 - fluoro - 4 - (trichloromethyl)benzene is shipped in specialized, leak - proof containers. It's handled with care due to its chemical nature, following strict regulations for safe transportation to prevent environmental and safety hazards.
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1-Fluoro-4-(Trichloromethyl)Benzene 1-Fluoro-4-(Trichloromethyl)Benzene
General Information
Historical Development
1 - Fluoro - 4 - (Trichloromethyl) Benzene is a special chemical product. Back in the past, its development process has been tortuous. At the beginning, chemists studied fluorine and chlorine-containing compounds to find unique properties. At that time, many experiments explored the possibility of fluorine and chlorine elements being replaced at specific positions in the benzene ring.
After long-term exploration and repeated trial and error, scholars gradually clarified the direction of specific structural combinations. With the improvement of chemical techniques and analytical methods, the molecular structure is more accurately controlled.
At a certain stage, 1 - Fluoro - 4 - (Trichloromethyl) Benzene was successfully synthesized. After that, in-depth exploration was carried out around its properties and applications. The birth of this compound is an important development in the history of chemical research and development, paving the way for more related research and applications in the future.
Product Overview
1 - Fluoro - 4 - (Trichloromethyl) Benzene is also an organic compound. Its color may be colorless to light yellow transparent liquid with a special odor. In this compound, the fluorine atom is connected to the benzene ring containing trichloromethyl, and the structure is unique.
In the field of chemical synthesis, 1 - Fluoro - 4 - (Trichloromethyl) Benzene is often an important intermediate. Due to its substituent properties on the benzene ring, it can participate in a variety of chemical reactions, such as nucleophilic substitution, coupling reactions, etc., and assist in the synthesis of various complex organic molecules.
In industrial applications, or for the preparation of materials with special properties, pharmaceutical intermediates, etc. Although it is toxic and volatile, it is necessary to pay attention to safety protection and follow relevant procedures when using it to ensure the safety of personnel and the environment.
Physical & Chemical Properties
1 - Fluoro - 4 - (Trichloromethyl) Benzene is also an organic compound. Its physical and chemical properties are related to many aspects. Looking at its physical properties, it may be in a liquid state at room temperature and has a special odor. Its boiling point, melting point, etc. are the keys to characterizing its physical state. As for chemical properties, due to the presence of fluorine and trichloromethyl groups, the reactivity is unique. The presence of fluorine atoms changes the electron cloud density of the benzene ring, affecting the activity and check point of electrophilic substitution reactions. Trichloromethyl can participate in a variety of chemical reactions, such as hydrolysis, reduction, etc. Its solubility may perform well in organic solvents, but it is not good in water. The physicochemical properties of this compound are the basis for the study of its application and reaction mechanism, and are of great significance in the fields of organic synthesis and materials science.
Technical Specifications & Labeling
1 - Fluoro - 4 - (Trichloromethyl) Benzene is an important chemical substance. Regarding its technical specifications and identification (product parameters), it is described below. The appearance of this substance is colorless to light yellow liquid with a special odor. Its boiling point is about [X] ° C, its melting point is about [X] ° C, and its density is [X] g/cm ³. In terms of technical specifications, the purity should be above [specific purity value], and the impurity content should be strictly controlled at a very low level. In terms of identification, the product packaging should clearly mark the name, chemical formula, hazard category and other key information. Its dangerous characteristics are that it is toxic and corrosive to a certain extent. When using and storing, relevant safety procedures must be strictly followed to prevent harm to personal safety and the environment. Only in this way can we ensure the safe and effective application of this product in industrial production and other fields.
Preparation Method
1 - Fluoro - 4 - (Trichloromethyl) Benzene is an important chemical. The preparation method, raw materials and production process are the key. The raw materials need to be selected carefully, such as specific fluorine-containing and chlorine-containing compounds as the starting point. In the production process, the reaction steps are step by step. First, the fluorine-containing compound and a chlorine-containing substrate are reacted at a suitable temperature and pressure under the action of a specific catalyst. This catalyst may accelerate the reaction process and improve the yield. After several steps of reaction, the preliminary product is generated, and then it is carefully processed to optimize the reaction conditions. The reaction time and temperature are strictly controlled to ensure the purity of the product. In this way, through a series of steps, this 1-Fluoro-4- (Trichloromethyl) Benzene can be obtained, and each link is closely related to the quality and yield of the product.
Chemical Reactions & Modifications
1 - Fluoro - 4 - (Trichloromethyl) Benzene is an organic compound, and its chemical reaction and modification are extremely critical. In the field of chemical research, explore the reaction characteristics of this compound, aiming to improve its properties and expand its application scope.
Looking at its chemical reaction, when it encounters nucleophiles, halogen atoms are active and prone to substitution reactions, and can introduce other functional groups, laying the foundation for the construction of complex structures. For its modification, chemical modification can be used to change the molecular structure to optimize physical and chemical properties such as stability and solubility.
To improve the stability of 1 - Fluoro - 4 - (Trichloromethyl) Benzene, an electron donor group can be added to the benzene ring, and the distribution of molecular electron clouds can be more stable through the conjugation effect. In this way, it may be able to find a wider application in the field of materials science and open up new paths for related research and practice.
Synonyms & Product Names
1 - Fluoro - 4 - (Trichloromethyl) Benzene, in the field of my chemical research, its synonymous name and trade name are the key to research.
Considering the past, the names of chemical substances often have many synonymous names due to differences in regions and research groups. For 1 - Fluoro - 4 - (Trichloromethyl) Benzene, there are also other names. Its synonymous names, although they refer to this thing, may be expressed differently. In the combing of research materials and academic exchanges, it needs to be carefully screened to prevent confusion.
As for the trade name, it is related to the market circulation of this thing. In order to recognize the characteristics of their products, different manufacturers give different trade names. Or highlight its purity, or emphasize its use. Knowing its trade name is of great benefit to the procurement and application of chemical substances.
The synonymous names and trade names of 1 - Fluoro - 4 - (Trichloromethyl) Benzene are like nodes in a chemical knowledge network, connecting many links in research, production and application, which cannot be ignored.
Safety & Operational Standards
1 - Fluoro - 4 - (Trichloromethyl) Benzene is an important chemical substance. Many points need to be paid attention to in terms of its safe production and operation practices.
The first word is safe. This substance has certain potential hazards. When storing, it should be placed in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent danger. Handle with care during handling to avoid leakage due to damage to the container.
Operators must be specially trained and strictly follow established procedures. Appropriate protective equipment such as protective glasses, gloves and protective clothing should be equipped during operation to ensure safety. At the place of use, corresponding leakage emergency treatment equipment and suitable containment materials should be prepared.
In the unfortunate event of a leak, personnel from the contaminated area of the leak should be quickly evacuated to a safe area and quarantined, and access should be strictly restricted. Emergency responders should wear self-contained positive pressure breathing apparatus and anti-acid and alkali work clothes. Do not let leaks come into contact with combustible substances. In the event of a small leak, a mixture of sand, dry lime or soda ash can be used and collected in a dry, clean, covered container. Large leaks should be built embankments or dug for containment, covered with foam to reduce volatilization.
During the preparation and use of 1-Fluoro-4- (Trichloromethyl) Benzene, precise control of the reaction conditions is crucial. Temperature, pressure, and the proportion of reactants all affect the quality and safety of the product. The reaction device also needs to be regularly inspected and maintained to ensure that there are no leaks and hidden dangers.
Only by strictly following safety and operating standards can we ensure the smooth operation of 1-Fluoro-4- (Trichloromethyl) Benzene and ensure the safety of personnel and the environment.
Application Area
1 - Fluoro - 4 - (Trichloromethyl) Benzene, this chemical has a wide range of application fields. In industrial manufacturing, it can be used as a key raw material for the synthesis of special materials. With its unique chemical properties, synthetic materials can have special properties, such as enhancing the stability and tolerance of materials.
In scientific research and exploration, it is also an important research object. Scholars use it to deeply explore the reaction mechanism of organic chemistry and help develop new synthesis methods. And in the field of pharmaceutical research and development, it may provide new ideas for the development of innovative drugs, which is expected to become an opportunity to break through the limitations of existing drugs. In conclusion, 1 - Fluoro - 4 - (Trichloromethyl) Benzene has shown great potential in many application fields and is of great significance to promote the development of various fields.
Research & Development
In recent years, I have studied chemical substances, especially the product 1 - Fluoro - 4 - (Trichloromethyl) Benzene. When I first started, its nature was unknown, and it was difficult to make it. I studied day and night, consulted countless books, and observed the methods of predecessors, all of which were deficient.
Then I created a new way, and after months of experiments, I adjusted its formula and changed its process. At first, the obtained product was not pure, and the yield was quite low. However, I was not discouraged, and I considered it repeatedly, and finally found a good method. The purity of the 1 - Fluoro - 4 - (Trichloromethyl) Benzene made has greatly increased, and the yield can also be seen.
Looking at this result now, it is the result of my unremitting research. In the future, we will continue to make progress and explore more uses for it, with the hope of making greater progress in the field of chemistry, enhancing the brilliance of the academic community, and promoting the wide application of this product for the benefit of the world.
Toxicity Research
Toxicity Study of 1 - Fluoro - 4 - (Trichloromethyl) Benzene
Today's research on 1 - Fluoro - 4 - (Trichloromethyl) Benzene is concerned with its toxicity, and our generation has carefully investigated it. This substance may have applications in various fields of chemical industry, but its impact on the health of the people and the surrounding world is not yet clear, so it needs to be studied in detail.
We have used various scientific methods to observe its behavior on micro-bodies, plants, and even water, soil, and air. After repeated experiments, it was found that this substance may have certain toxicity. In the micro-body experiment, the subjects showed various abnormalities, and their physiological functions were disturbed by it. And in the context of environmental simulation, it also has adverse effects on water and soil ecology.
However, if you want to exhaust the full picture of its toxicity, you need to study it for a long time, collect data widely, and analyze it in detail. Hope this research can provide evidence for the control and application of this thing in the future, to protect the safety of the people and protect the environment.
Future Prospects
In the future, 1 - Fluoro - 4 - (Trichloromethyl) Benzene is a compound that contains chemical resistance. It can be used in the field of synthesis, or it can be used as a new way. Or it can be used in the field of synthesis to assist in the synthesis of many materials with special properties.
In the direction of research, it can be skillfully modified, or it can give birth to new materials with excellent biological activity and targeting.
In the application of technology, it is expected to improve the properties of some products, such as the resistance of chemical materials, the quality of plastics, etc. However, in order to achieve this goal, researchers still need to make unremitting research, overcome the synthesis, reduce the cost and increase the efficiency, in order to fully realize its unrealized value and improve the prospects.
Where to Buy 1-Fluoro-4-(Trichloromethyl)Benzene in China?
As a trusted 1-Fluoro-4-(Trichloromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Fluoro-4-(Trichloromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Fluoro-4- (Trichloromethyl) Benzene?
1-Fluoro-4- (trichloromethyl) benzene, this is an organic compound with a wide range of uses. In the chemical industry, it is often used as a key intermediate in organic synthesis. With its unique structure, it can participate in many chemical reactions to prepare various organic compounds with specific properties.
In the field of materials science, polymer materials with excellent performance can be prepared from this raw material. The fluorine atom and trichloromethyl group of this compound can give the material excellent properties such as chemical resistance, thermal stability and low surface energy. The materials obtained in this way can be used in coatings, plastics and other industries to improve the quality and durability of products.
In the field of pharmaceutical research, 1-fluoro-4- (trichloromethyl) benzene is also of great value. Due to its structural particularity, it may become a starting material for the development of new drugs. By structural modification and modification, compounds with specific biological activities may be obtained for the treatment and prevention of diseases.
In addition, in the field of pesticides, this compound is also useful. Its unique chemical structure or endow it with certain biological activities can be used as the basis for the development of new pesticides, which can be used to control crop diseases and insect pests and ensure the harvest of agricultural production. Overall, 1-fluoro-4 - (trichloromethyl) benzene plays an important role in many fields such as chemical industry, materials, medicine, pesticides, etc., and plays a key role in promoting the development of various fields.
What are the physical properties of 1-Fluoro-4- (Trichloromethyl) Benzene?
1-Fluoro-4- (trichloromethyl) benzene is also an organic compound. Its physical properties are quite important, and it is used in chemical industry.
Looking at its properties, under normal circumstances, this substance is a colorless to slightly yellow liquid, like water, and has a special odor. Smell it, the taste is pungent, although this smell has no specific fragrance, everyone can feel it, and those who smell it often feel uncomfortable.
Its boiling point is about 208 ° C - 210 ° C. At this temperature, the liquid will gradually turn into a gas and rise in the air. The boiling point is so because of the force between molecules. The strength of the attractive force between molecules determines the level of the boiling point. Due to the molecular structure of this substance, the attractive force between molecules is moderate, so the boiling point is like this.
Besides the melting point, it is about -26 ° C. When the temperature drops to this point, the liquid gradually condenses into a solid, just like the formation of ice in water. The melting point is also related to the molecular structure. The structure is stable and orderly, and the melting point is high; otherwise, it is low. The molecular arrangement of this substance causes its melting point to be at this value.
The density is about 1.49g/cm ³, which is heavier than water. Placing it in one place with water will sink to the bottom of the water, like a stone falling into an abyss. Because of the molecular mass and the degree of close arrangement, the mass and dense arrangement will cause the density to be high.
In terms of solubility, 1-fluoro-4- (trichloromethyl) benzene is insoluble in water, and the two meet, such as oil and water, which are distinct. However, it is soluble in many organic solvents, such as ethanol, ether, etc. The molecular structure of organic solvents is similar to this substance, and according to the principle of "similar compatibility", the two are soluble.
Its volatility is also considerable. At room temperature, placed in an open container, it evaporates slowly. The molecule is energized and escapes from the liquid surface and enters the air. When storing and using this property, attention should be paid to it to prevent loss and safety risks.
These physical properties are crucial in chemical production, scientific research, etc. Knowing its boiling point can be used for distillation separation; knowing its solubility can help with extraction and purification. Therefore, it is essential to clarify its physical properties when using this product.
Is 1-Fluoro-4- (Trichloromethyl) Benzene Chemically Stable?
The stability of the chemical properties of 1-fluoro-4- (trichloromethyl) benzene is related to many chemical principles, which should be explored in detail. In this compound, fluorine atoms and trichloromethyl are co-attached to the benzene ring. Fluorine atoms have strong electronegativity, which can reduce the electron cloud density of the benzene ring, reduce the electrophilic substitution activity of the benzene ring, and stabilize the molecule to a certain extent.
In addition, trichloromethyl is also an electron-withdrawing group, which conjugates with the benzene ring, strengthening the inhomogeneity of the molecular electron cloud distribution, but also making the benzene ring system more stable. However, this stability is not absolute, and can also react under specific conditions. In case of strong nucleophilic reagents, fluorine atoms may be replaced by nucleophilic due to changes in the distribution of electron clouds in the benzene ring, which indicates that their stability can be changed due to the external chemical environment.
In addition, in case of high temperature, light and other conditions, the intra-molecular energy increases, the vibration of chemical bonds intensifies, or it undergoes cracking or rearrangement reactions, which also proves that its stability is not static. Therefore, the stability of 1-fluoro-4- (trichloromethyl) benzene cannot be generalized, but depends on the specific chemical situation and conditions. When it is at room temperature and pressure without the interference of strong active reagents, its chemical properties are still stable; however, if the environment changes, it may exhibit active chemical behaviors and participate in various chemical reactions.
What is the production method of 1-Fluoro-4- (Trichloromethyl) Benzene?
1-Fluoro-4- (trichloromethyl) benzene, also known as p-fluorotrichlorotoluene, has the following common preparation methods:
First, p-chlorotoluene is used as raw material and prepared by fluorination reaction. This is a more commonly used method. P-chlorotoluene and fluorinating agents, such as potassium fluoride, are placed in a specific reaction vessel, and appropriate catalysts and solvents are added. Under suitable temperature and pressure conditions, the fluoride ions in potassium fluoride will react with the chlorine atoms of p-chlorotoluene to gradually generate 1-fluoro-4- (trichloromethyl) benzene. During the reaction, the temperature, pressure and the proportion of reactants need to be precisely controlled to improve the yield and purity of the product. For example, in a suitable organic solvent, the reaction temperature is controlled within a certain range, and the input of potassium fluoride and p-chlorotrichlorotoluene in an appropriate molar ratio can promote the efficient progress of the reaction.
Second, p-fluorotoluene is used as the starting material and prepared by chlorination reaction. The p-fluorotoluene is placed in the chlorination reaction system, and chlorine gas is introduced. Under the action of light or initiator, the hydrogen atoms on the methyl group of toluene will be gradually replaced by chlorine atoms, and finally 1-fluoro-4- (trichloromethyl) benzene will be formed. This process requires attention to the regulation of reaction conditions, such as light intensity, chlorine gas entry speed, reaction temperature, etc. Insufficient light intensity or too slow chlorine gas entry may cause incomplete reactions; and if the temperature is too high, many side reactions may occur, affecting the quality and yield of the product.
Third, other related compounds are used as starting materials and synthesized through multi-step reactions. For example, based on specific aromatic compounds, through a series of substitution, addition and other reactions, the target molecular structure is gradually constructed. Although this method is complicated, in some specific cases, it is feasible because of the convenience of obtaining raw materials or the extremely high requirements for product purity. However, the multi-step reaction requires careful planning of the reaction conditions and separation and purification steps at each step to ensure the feasibility and economy of the overall synthesis route.
1-Fluoro-4- (Trichloromethyl) Benzene requires attention during storage and transportation
1-Fluoro-4- (trichloromethyl) benzene is also an organic compound. When storing and transporting it, many matters need to be paid attention to.
First words storage. This substance should be placed in a cool and ventilated warehouse. Because of the cool and ventilated place, it can avoid the risk of thermal decomposition or aggravation of reaction due to excessive temperature. The temperature of the warehouse should not be too high to prevent accidents. And it should be kept away from fire and heat sources, both of which can cause danger, or cause combustion or even explosion. It should be stored separately from oxidizing agents, alkalis, etc., and should not be mixed. Both edge oxidants and alkalis may chemically react with 1-fluoro-4- (trichloromethyl) benzene, causing it to deteriorate or produce dangerous substances. At the same time, the warehouse should have suitable materials to contain leaks to deal with in case of leakage and not expand the harm.
Second talk about transportation. Be sure to ensure that the packaging is complete and the loading is safe before transportation. If the packaging is incomplete, it may cause leakage during transportation, polluting the environment and endangering the safety of transportation personnel. Unstable loading may cause package damage during transportation. During transportation, also ensure that the container does not leak, collapse, fall or damage. Transportation vehicles should be equipped with corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment. In the event of a leak or fire, it can be disposed of in time. And when transporting, follow the specified route and do not stop in densely populated areas and residential areas to avoid harming many people. In short, the storage and transportation of 1-fluoro-4- (trichloromethyl) benzene must be done with caution and follow relevant regulations to ensure safety.