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1-Fluoro-4-Methyl-2-Nitrobenzene

1-Fluoro-4-Methyl-2-Nitrobenzene

Hongda Chemical

Specifications

HS Code

956707

Chemical Formula C7H6FNO2
Molecular Weight 155.13
Appearance Solid
Color Yellow to light brown
Melting Point 44 - 48 °C
Boiling Point 223 - 225 °C
Density 1.314 g/cm³
Solubility In Water Insoluble
Flash Point 99 °C
Purity Typically high - can vary by supplier

As an accredited 1-Fluoro-4-Methyl-2-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - fluoro - 4 - methyl - 2 - nitrobenzene: Packed in 500g bottles for chemical storage.
Storage 1 - fluoro - 4 - methyl - 2 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from sources of heat, ignition, and oxidizing agents. Store in a tightly sealed container to prevent leakage. This nitro - containing aromatic compound may be reactive, so separate it from incompatible substances. Label the storage clearly for easy identification and safety.
Shipping 1 - fluoro - 4 - methyl - 2 - nitrobenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, with proper labeling and handling to ensure safe transport.
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1-Fluoro-4-Methyl-2-Nitrobenzene 1-Fluoro-4-Methyl-2-Nitrobenzene
General Information
Historical Development
1 - Fluoro - 4 - Methyl - 2 - Nitrobenzene is an organic compound, and its historical development is quite important. In the past, the beginning of organic chemistry, many sages dedicated themselves to the exploration and analysis of compounds.
At the beginning, the understanding of this compound was still shallow, and only a little appearance was observed. However, with the improvement of chemical technology, the analytical methods became more accurate. Chemists worked tirelessly, from simple experimental equipment to exquisite instrument analysis, and gradually clarified its structure and characteristics.
In the early days, it was difficult to synthesize this compound, and the yield was low. After countless attempts, the reaction conditions were optimized and the synthesis path was improved, so that the yield could be improved. Many chemists have continued to contribute to the development of 1-Fluoro-4-Methyl-2-Nitrobenzene, eventually enabling it to occupy a place in the field of organic synthesis and become more widely used.
Product Overview
1 - Fluoro - 4 - Methyl - 2 - Nitrobenzene is an important compound in organic synthesis. Its properties are light yellow to yellow liquid, with a unique odor. The melting point is about [specific value], and the boiling point is around [specific value].
This compound has a wide range of uses in the chemical industry. In the pharmaceutical synthesis path, it is often used as a key intermediate to assist in the preparation of many specific drugs. In the field of materials science, it also plays an indispensable role in optimizing the properties of materials.
Synthesis of this compound, a common method is to use a specific benzene derivative as the starting material, through a series of precise reactions such as halogenation, nitrification, and methylation. The reaction process requires strict control of temperature, pressure and reactant ratio to ensure high yield and high purity.
When storing and transporting, pay attention to its chemical properties. Because of its certain chemical activity, it should be protected from heat and moisture, and stored in a cool and ventilated place to prevent deterioration or danger. In this way, the effect of 1-Fluoro-4-Methyl-2-Nitrobenzene can be better exerted to serve the development of various fields.
Physical & Chemical Properties
1 - Fluoro - 4 - Methyl - 2 - Nitrobenzene is an organic compound. Its physical and chemical properties are particularly important. Looking at its properties, it may be liquid at room temperature and has a specific color and taste. In terms of solubility, it may have a certain solubility in organic solvents, but it may have very little solubility in water.
Its boiling point is related to the intermolecular force, or has a unique value due to the presence of nitro, fluoro and methyl groups. The melting point is also affected by the molecular structure. The spatial arrangement and interaction of these groups determine the temperature at which the solid state is converted to liquid state.
When it comes to chemical properties, nitro groups have strong electron absorption, which reduces the density of the electron cloud of the benzene ring and causes its electrophilic substitution reaction activity to change. Fluorine atoms have high electronegativity, which affects the polarity of molecules and also has an effect on reactivity. Methyl groups, on the other hand, interact with other groups to jointly determine the reaction path and product of this compound.
Technical Specifications & Labeling
1 - Fluoro - 4 - Methyl - 2 - Nitrobenzene is an organic compound. Its process specification, the purity of the first raw material. Fluoride, methyl benzene, nitro agent are used in appropriate proportions, and the reactor must be clean and firm. Control the temperature to a moderate extent, do not make it too high or too low, too high will increase by-products, and too low will slow the reaction. When reacting, stir it often to make it uniform and fast.
Its logo, when the name of this declaration is "1 - Fluoro - 4 - Methyl - 2 - Nitrobenzene", is attached with the molecular formula and molecular weight. On the packaging, mark dangerous, such as poisonous and flammable. Remember the method of storage, it should be placed in a cool and dry place, away from fire and oxidants. In this way, the quality of this thing can be guaranteed and it is safe to use.
Preparation Method
1 - Fluoro - 4 - Methyl - 2 - Nitrobenzene is an important compound in organic synthesis. Its preparation method is related to raw materials, production process, reaction steps and catalytic mechanism.
To prepare this compound, 4 - methyl - 2 - nitroaniline is often used as the initial raw material. First, it is mixed with an appropriate amount of hydrofluoric acid and sodium nitrite in a low temperature environment to undergo diazotization. This step requires precise control of the temperature and the ratio of the reactants to ensure the smooth progress of the reaction.
Subsequently, under the action of the catalyst, the diazonium salt undergoes a fluorination reaction to generate 1 - Fluoro - 4 - Methyl - 2 - Nitrobenzene. The catalyst used is usually a fluorine-containing compound, which can effectively promote the reaction and improve the yield of the product.
Accurate control of the reaction conditions is crucial throughout the production process. Temperature, pressure, reaction time and other factors will all affect the quality and yield of the product. It needs to be optimized by many experiments to determine the best reaction parameters and achieve an efficient and stable preparation process.
Chemical Reactions & Modifications
Taste the wonders of chemistry, with all kinds of changes, related to the transformation of substances and the change of properties. On this chemical product 1 - Fluoro - 4 - Methyl - 2 - Nitrobenzene. Its chemical reaction is like a change in the universe. In the reaction, fluorine, methyl, and nitro groups interact, or nucleophilic substitution, or electron cloud migration, to form a new structure.
And its variability is related to physical and chemical properties. The introduction of fluorine increases its electronegativity, changes the polarity of the molecule, and affects the melting point and solubility. Methyl adds its fat solubility, and nitro has strong oxidation. The three coexist, making this compound unique in performance. If you want to make good use of it, you must deeply study its reaction mechanism and understand its changing rules, so that it can be used in the chemical industry, medicine and other industries, and benefit the world. It is also the responsibility of chemical researchers.
Synonyms & Product Names
1 - Fluoro - 4 - Methyl - 2 - Nitrobenzene, this substance is also a chemical substance. Its synonymous name and the name of the commodity are quite elegant.
A person with a synonymous name is named after the principle of chemistry, or according to its structure, or according to its characteristics. Such as "fluoromethylnitrobenzene" is famous for its fluorine-containing, methyl-nitro group, and its structure.
As for the name of the commodity, merchants make a profit, wanting its name to be obvious and easy to remember, in order to attract customers. Or take its unique nature, or with auspicious meaning. For example, the name "Rui Fluoronitrotoluene" or "Rui" means auspiciousness and hopes that the sales of its products will be smooth.
All such synonymous names and commodity names are for the convenience of everyone. Only when a chemical researcher in Uwu is familiar with all names can he travel freely in the realm of academia and industry without confusion.
Safety & Operational Standards
1 - Fluoro - 4 - Methyl - 2 - Nitrobenzene is a chemical substance, and it is necessary to be careful about its safety and operation specifications.
This substance is dangerous to a certain extent, and when operating, the safety of the environment is the first priority. When choosing a well-ventilated place to prevent the accumulation of harmful gases. If you work in a closed place, the toxic gas will not dissipate, which will endanger the person. And the operating site should be far away from fire and heat sources. Because of its flammability, it may encounter open flames, hot topics, fear fire, or even explosion, which will cause disaster.
Operators also need appropriate protective equipment. When wearing a gas mask to prevent harmful gases from entering the body and damaging the respiratory system. Chemical protective gloves should be worn on both hands to avoid contact with the skin, because it may be corrosive and will hurt if touched. Wear protective clothing to protect the body in an all-round way.
There are also strict regulations on storage. It should be stored in a cool, dry place away from direct sunlight. And it should be stored separately from oxidizing agents and reducing agents, and must not be mixed to prevent chemical reactions from occurring and causing safety hazards.
When taking it, the action should be stable and accurate. Take the equipment and method according to the exact amount and operate it. Do not take more or less. If there is any spill, clean it up immediately and dispose of it according to relevant procedures. Do not let it remain, leaving hidden dangers.
After use, the leftovers and waste must not be discarded at will. It must be properly handled according to specific environmental protection and safety requirements to ensure that the environment is not polluted and no future problems are caused.
In short, the safety and operation specifications of 1 - Fluoro - 4 - Methyl - 2 - Nitrobenzene are interlinked, which is related to human life and the environment. All should be cautious and not slack in the slightest.
Application Area
1 - Fluoro - 4 - Methyl - 2 - Nitrobenzene is an organic compound with a wide range of application fields. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create drugs with specific effects. Through its unique chemical structure, it participates in multi-step reactions to achieve the construction of target drug molecules. In the field of materials science, this compound can be modified to prepare special materials, such as materials with specific optoelectronic properties, contributing to the development of new materials. In the fine chemical industry, it can be used to synthesize fine chemicals with special functions, such as certain high-performance dyes and fragrances, giving products unique properties and application value. All these application fields rely on the chemical properties of 1 - Fluoro - 4 - Methyl - 2 - Nitrobenzene, and with the deepening of research, its application potential may be more fully demonstrated.
Research & Development
Taste the way of scientific research, the most important thing is to explore and innovate. Today, in 1 - Fluoro - 4 - Methyl - 2 - Nitrobenzene, I have devoted myself to studying it. At first, I observed its physical properties, explored its structure, and understood the wonders of its molecules. Then, I thought about the method of preparation. After many attempts, I either improved the old technique or innovated the new path, and strived for high efficiency and purity. During this period, I encountered many difficulties, such as the harsh reaction conditions and the cumbersome separation of products. However, I have unremitting research and repeated experiments, and finally achieved results. This achievement may have considerable application prospects in many fields such as chemical medicine. In the future, we will continue to make progress, explore its potential characteristics in depth, and expand the scope of application, with the hope of contributing to the development of scientific research, so that the research and development of this substance can reach a new height.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons in it cannot be ignored. Today there is 1-Fluoro-4-Methyl-2-Nitrobenzene, and the study of its toxicity is quite important.
Observe this substance, in the experiment, observe its effect on various substances. Take white mice as a test, feed on food containing this substance. Not long after, the behavior of white mice is different, the movement is slow, and the feeding is gradually less.
Reanalyze the principle, this substance enters the body, or disturbs the biochemical process. The activity of enzymes changes accordingly, causing metabolism to be blocked. And in the state of cells, it also changes, or damages its structure, or disrupts its function.
From this point of view, 1 - Fluoro - 4 - Methyl - 2 - Nitrobenzene is significantly toxic. When used in production, care should be taken to study the protective methods in detail to avoid harming living beings and leaving disasters in the world.
Future Prospects
I have dedicated myself to studying this chemical 1 - Fluoro - 4 - Methyl - 2 - Nitrobenzene. Looking at its characteristics, it contains extraordinary potential, just like a pearl hidden in darkness, and we urgently need to use our wisdom and skills to make it shine.
Looking to the future, this chemical may have a major breakthrough in the field of medicine. Or with its unique structure, we can develop new special drugs, save many patients with serious diseases, and add luster to the apricot forest. In the field of materials science, it is also expected to use its characteristics to create new materials with excellent performance, which can be applied to key fields such as aerospace and electronics, and promote science and technology to make great progress.
Our scientific researchers should have great ambitions and make unremitting explorations. With perseverance, we will study its mysteries and tap its endless potential. Looking forward to seeing this chemical bloom in the near future, creating immortal deeds for human well-being and technological progress, in recognition of our original intention and ambition of scientific research.
Where to Buy 1-Fluoro-4-Methyl-2-Nitrobenzene in China?
As a trusted 1-Fluoro-4-Methyl-2-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Fluoro-4-Methyl-2-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Fluoro-4-Methyl-2-Nitrobenzene?
1-Fluoro-4-methyl-2-nitrobenzene is also an organic compound. It has a wide range of uses and has important applications in various fields of chemical industry.
Bearing the brunt, this compound is often a key intermediary in the synthesis of medicine. Due to its special chemical structure, it can be constructed through various chemical reactions with specific pharmacological activities. For example, through clever reaction design, other functional groups can be introduced to prepare drugs for specific diseases, such as antibacterial and anti-inflammatory drugs, to help maintain human health.
Furthermore, in the process of pesticide creation, 1-fluoro-4-methyl-2-nitrobenzene also plays an important role. It can be used as a starting material for the synthesis of high-efficiency pesticides. Through chemical transformation, pesticide ingredients with high selectivity and high activity to pests can be synthesized. These pesticides can effectively kill pests, and at the same time have relatively little impact on the environment. They contribute to the sustainable development of agriculture, protect the growth of crops, and ensure the harvest of food.
In addition, in the field of materials science, it can also be seen. Or it can be used to synthesize polymer materials with special properties, such as materials with excellent heat resistance and chemical corrosion resistance. Such materials are in high demand in high-end fields such as aerospace, electronics and electrical appliances, which can improve the performance and service life of related equipment and products.
In the field of dye industry, 1-fluoro-4-methyl-2-nitrobenzene can be used as the basic raw material for synthesizing new dyes. Carefully synthesized dyes may have the advantages of bright color and good light fastness, and are widely used in textile, printing and dyeing industries, adding gorgeous colors to people's lives.
In summary, 1-fluoro-4-methyl-2-nitrobenzene plays an important role in many industrial fields such as medicine, pesticides, materials, dyes, etc., and has made significant contributions to the development of various industries.
What are the physical properties of 1-Fluoro-4-Methyl-2-Nitrobenzene?
1-Fluoro-4-methyl-2-nitrobenzene is an organic compound. Its physical properties are particularly important and are related to applications in chemical, pharmaceutical and other fields.
First of all, its appearance is often light yellow to light brown crystalline powder or liquid, depending on the temperature environment. It has a unique color, which is one of the aids to distinguish.
When it comes to the melting point, it is about 28-30 ° C. When the temperature reaches this point, the state of matter gradually melts from the solid state to the liquid state. This phase transition temperature needs to be paid attention to when separating, purifying and storing.
The boiling point is about 236-238 ° C. At this temperature, the compound is liquefied into a gaseous state. In distillation and other operations, this boiling point is a key parameter, which can help to separate mixtures with different boiling points.
The density is about 1.32 g/cm ³, which is slightly higher than that of water. In the process of liquid-liquid separation or mixing, the density characteristics depend on its position and distribution in the system.
In terms of solubility, 1-fluoro-4-methyl-2-nitrobenzene is slightly soluble in water. Due to the strong hydrogen bond between water molecules, and the polarity of the compound is limited, the interaction with water is weak. However, it is soluble in many organic solvents, such as ethanol, ether, acetone, etc. The molecular structure and polarity of the organic solvent are in line with the compound, so it can be mutually soluble. This solubility is crucial in organic synthesis, extraction and other steps.
In addition, the compound has a certain volatility. At room temperature, some molecules escape from the liquid level and enter the gas phase. This characteristic should be paid attention to ventilation in storage and use places to prevent its accumulation in the air and cause safety hazards.
In short, the physical properties of 1-fluoro-4-methyl-2-nitrobenzene, such as appearance, melting point, boiling point, density, solubility and volatility, are all indispensable factors in chemical production and scientific research. Those who operate it must carefully observe and make good use of it.
What are the chemical properties of 1-Fluoro-4-Methyl-2-Nitrobenzene?
1-Fluoro-4-methyl-2-nitrobenzene is one of the organic compounds. Its chemical properties are unique and valuable to explore.
First of all, its reactivity. On the benzene ring, fluorine atoms, methyl groups and nitro groups coexist. Nitro is a strong electron-absorbing group, which can reduce the electron cloud density of the benzene ring and weaken the electrophilic substitution reaction activity of the benzene ring. And the presence of nitro groups decreases the electron cloud density of the adjacent and para-position especially, and the meta-position is relatively high, so the electrophilic substitution reaction easily occurs in the meta-position.
methyl is the electron donator group, which can increase the electron cloud density of the benzene ring, and can improve the electrophilic substitution activity of the benzene ring to a certain extent. Although fluorine atoms have electron-absorbing induction effects, they also have electron-donator conjugation effects, which have a complex impact on the distribution of electron clouds in the benzene ring.
Re-discuss its reaction with nucleophiles. Due to the strong electron-absorbing action of nitro groups, the electron cloud density of carbon atoms in the benzene ring at the o and p sites decreases, making them vulnerable to attack by nucleophiles, and nucleophilic substitution reactions can occur.
In the reduction reaction, nitro groups can be reduced. For example, with a suitable reducing agent, nitro groups can be gradually reduced to amino groups. This process is widely used in organic synthesis, and amino functional groups can be introduced to lay the foundation for subsequent reactions.
And because of its fluorine-containing atoms, fluorine atoms can undergo substitution reactions under certain specific conditions, providing the possibility for the modification of molecular structures.
The chemical properties of 1-fluoro-4-methyl-2-nitrobenzene are formed by the interaction of functional groups in its molecules, which has important applications and research significance in many fields such as organic synthesis and medicinal chemistry.
What is 1-Fluoro-4-Methyl-2-Nitrobenzene production method?
The preparation method of 1-fluoro-4-methyl-2-nitrobenzene, although the ancient book "Tiangong Kaiwu" does not directly describe this substance, it can be deduced from similar chemical methods.
Ancient chemical industry often starts with natural substances. When preparing 1-fluoro-4-methyl-2-nitrobenzene, natural substances containing benzene rings can be taken first, such as some aromatic plant extracts, through fractionation, purification, etc., to obtain pure benzene ring parent.
First, toluene is used as the initial material, because toluene contains methyl groups, part of the structure of this molecule is combined. Toluene and mixed acid (mixed nitric acid and sulfuric acid) are co-heated to carry out nitrification. Sulfuric acid is used as a catalyst to dissociate nitro-positive ions, and nitro-positive ions attack the benzene ring of toluene electrophilically. Due to the fact that methyl is an ortho-para-site group and the steric hindrance and other factors, the nitro is mostly substituted in the methyl ortho-site to obtain 2-nitrotoluene.
Second, 2-nitrotoluene is converted into 1-fluoro-4-methyl-2-nitrobenzene by halogenation. React with fluorine-containing reagents, such as potassium fluoride, etc. Under appropriate solvents and reaction conditions, fluorine ions nucleophilically replace halogen atoms at appropriate positions on the benzene ring (halogen atoms, such as chlorine atoms, need to be introduced first, and 2-nitro-4-chlorotoluene can be obtained by light or catalytic substitution of chlorine gas with 2-nitrotoluene), or through other nucleophilic substitution mechanisms, fluorine atoms are connected to the benzene ring, and finally 1-fluoro-4-methyl-2-nitrobenzene is obtained.
Although this preparation method is different from the traditional chemical industry contained in "Tiangong Kaiyi", it is based on chemical principles to convert materials to obtain target products, which is also in line with the exploration and innovation of ancient chemical industry.
What are the precautions in storage and transportation of 1-Fluoro-4-Methyl-2-Nitrobenzene?
1-Fluoro-4-methyl-2-nitrobenzene is also an organic compound. During storage and transportation, many matters must be paid attention to.
First words storage, this substance should be placed in a cool, dry and well ventilated place. Because of its certain chemical activity, high temperature and humidity may cause it to undergo chemical reactions, damage its quality, or even cause danger. In addition, it should be placed separately from oxidizing agents, reducing agents, alkalis and other substances. Due to its chemical properties, if mixed with the above substances, it is very easy to induce violent chemical reactions, such as combustion, explosion and other dangers. And the storage place should be clearly marked, indicating the name, characteristics and precautions of the substance, so as to facilitate access and management, and prevent the risk of misuse and misuse.
As for transportation, it should also be treated with caution. Transport equipment must be kept tight and tight to prevent material leakage. When loading, light loading and light unloading, to avoid collision and vibration, because of external force, or cause package damage, resulting in leakage. During transportation, drivers and escorts must be familiar with the characteristics of the substance and emergency treatment methods. In case of leakage and other emergencies, they can respond quickly and correctly. At the same time, the planning of transportation routes should avoid densely populated areas and environmentally sensitive areas, in case of leakage, causing serious harm to the public and the environment.
In short, 1-fluoro-4-methyl-2-nitrobenzene is a safe and quality product to be used in storage and transportation.