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What are the main uses of 1-fluoro-4-isothiocyanate phenyl ester?
The main user of 1-4-quartz acid herbs, in the Tao, has special power.
This kind of pain, taste sweet and bitter. Its primary use is to clear the fire. If the human body is prosperous, it will be inflamed like fire, causing dry mouth and tongue, sore throat, and sore eyes. 1-4-quartz acid herbs can be effective. With its quality, it clears the herbs, so that the evil fire can be released, and the disease will disappear.
Furthermore, it has the ability to facilitate water and drizzle. If the person is burnt, causing short red urine, dripping pain and other leaching, this can help the water and liquid to be smooth, so that the evil of the urine can come out, and the urine can be solved. It also has the power of reason in the loss of water and liquid replacement and the cessation of evil, which can make the evil have a way out, and improve the body, heaviness, abdominal stool, etc. caused by the evil.
And it is also effective in the liver. Liver, or mouth pain, pain, jaundice and other diseases, 1-4-stone acid can enter the liver, clear the liver, restore the normal drainage function of the liver, so that the liver can be removed, and the disease can be solved.
In ancient books, there are also many examples of its effectiveness. The generation of the family, according to the disease of the patient, the use of this product is reasonably compatible, and there are many good effects. However, when using this product, it is also necessary to be careful. According to the patient's condition, the severity of the condition and other factors, consider the dosage, and seek the best effect. And avoid the generation of adverse reactions.
What are the physical properties of phenyl 1-fluoro-4-isothiocyanate?
The physical properties of benzyl 1-alkane-4-isoferocyanate are as follows.
This compound exhibits a relatively stable state under normal temperature and pressure. Looking at its appearance, it is mostly a colorless to slightly yellow liquid with uniform texture and fluidity, as clear as a mountain spring, and no obvious turbidity or impurities can be seen.
Smelling its smell is not a pungent and unpleasant state, but has a light and specific aroma. Although this fragrance is not rich, it is unique, like a unique fragrance hidden in the flowers, attracting people to explore.
When it comes to density, compared to common water, its density is slightly higher. If it is placed in the same container as water, it can be seen that it sinks slowly, just like a stable person who falls to the ground. Its solubility in water is quite limited, and the two are like incompatible strangers. After meeting, they each maintain an independent state, and only a very small amount will merge with water.
Besides its melting point and boiling point, the melting point is relatively low, and it can still maintain a liquid state in a general low temperature environment. The boiling point is higher, and a considerable amount of heat needs to be applied to make it boil into a gaseous state. This characteristic makes it able to maintain a stable liquid state in many common temperature ranges, just like a guard who sticks to his post, and is not easily disturbed by external temperature.
In addition, the refractive index of benzyl 1-alkane-4-isofrocyanate also has its own unique characteristics. When light passes through this compound, the light will be refracted at a specific angle. This refractive angle is accurately measured to provide an important basis for its identification and analysis, just like a unique fingerprint, which becomes the key to identifying it. And it has a certain volatility. Although the volatilization rate is relatively slow, in the exposed environment, after a certain period of time, it can also be perceived that the amount of it decreases, just like the passage of time, which changes inadvertently.
Is 1-fluoro-4-isothiocyanate chemically stable?
1-%E6%B0%9F-4-%E5%BC%82%E7%A1%AB%E6%B0%B0%E9%85%B8%E8%8B%AF%E9%85%AF%E7%9A%84%E5%8C%96%E5%AD%A6%E6%80%A7%E8%B4%A8%E5%9D%9A%E7%A8%B3%E5%AE%9A%E4%B9%8B%E7%89%A9. Its properties are relatively safe under normal conditions. However, when encountering special agents or strips, it can also initiate chemical reactions.
The structure of this compound endows it with certain stability. In its molecular structure, the bonds between atoms are firm, making it difficult to break the molecular configuration easily. The row of carbon chains and the cloth of functional groups together build a stable foundation. Just like the structure of a strong city, bricks and stones are built into a stable state.
However, it must not be broken. When the external strip is appropriate, such as the temperature rises to a certain value, or when encountering something catalytic, its stable state can be disturbed. The increase in temperature gives more energy to the molecule, which intensifies the vibration of the atom. If the energy is sufficient, the intra-molecular bond can be broken. The catalyst can reduce the activation energy of the reaction, making it easy to initiate the reaction that was originally difficult to occur.
If 1-%E6%B0%9F-4-%E5%BC%82%E7%A1%AB%E6%B0%B0%E9%85%B8%E8%8B%AF%E9%85%AF encounter a specific metal catalyst in a certain chemical environment, it can initiate nucleophilic substitution with a certain reagent. This shows that although its normal state is stable, it can also show its active side when the chemical environment changes.
It is important that the chemical properties of 1-%E6%B0%9F-4-%E5%BC%82%E7%A1%AB%E6%B0%B0%E9%85%B8%E8%8B%AF%E9%85%AF are relatively stable, and their own structure and properties can be maintained under normal conditions; when it encounters a chemical strip, the latent activity in the molecule can be excited and induced to change.
What should be paid attention to when storing 1-fluoro-4-isothiocyanate?
1-4-Cerium lanthanum isoferocyanate, when hiding, should be careful of all things. This medicine has special characteristics, related to safety, must not be ignored.
First of all, it should be stored in a place. Must choose a dry, cool and well-ventilated place. When covered with moisture or heat, it is prone to changes and dangers. If it is wet or invaded by water vapor, its quality may change, and its medicinal power may also change, or even cause unexpected changes, endangering the surroundings. Heat will promote its rate of transformation and damage its inherent nature, so cool and dry places are essential.
Second and storage choice. When using a strong and corrosion-resistant device. The genus of glass, if the quality is pure and free of impurities, can ensure its stability. Avoid using easily corrosive utensils, such as ordinary iron utensils, it is easy to combine and damage its essence when encountered with them. And the utensils must be tightly sealed to prevent air from entering. If air contains various gases, oxygen will easily promote its oxidation, causing its qualitative change, and its medicinal power will not exist.
Furthermore, the logo is clear and indispensable. On the reservoir, write its name, nature, use and storage time in obvious words. One is easy to find, and the other is to prevent misuse. Where other things are mixed, misuse and misuse may cause serious harm.
It needs to be checked often. Observe its condition from time to time, observe the color, smell and taste, and check the quality. If there is any mutation, dispose of it quickly. Sleep early and break early to avoid disaster.
Store 1-2-4-cerium lanthanum isoferocyanate, carefully select storage places and utensils, clearly mark and check frequently, so that it is safe and safe to use.
What are the synthesis methods of 1-fluoro-4-isothiocyanate phenyl ester?
To prepare benzyl 1-alkyne-4-isoferocyanate, it can be obtained from the classical organic synthesis method. The first method is to react with halogenated hydrocarbons and alkynides as the basis. First, take halogenated benzyl, such as benzyl bromide, and add sodium alkynide or potassium alkynide to a suitable solvent, such as liquid ammonia or ether solvents. According to the principle of nucleophilic substitution, the halogenated atom is replaced by an alkynyl group, and the 1-alkynyl-benzyl intermediate can be obtained. After that, the intermediate is reacted with the isoferric acid reagent to adjust the reaction conditions, such as temperature and pH, to promote the access of isoferocyanate groups, and finally obtain 1-alkynyl-4-is
Method 2, starting from alkynyl alcohol. First, alkynyl alcohol is reacted with a suitable protecting group to protect the hydroxyl group from interference in subsequent reactions. After halogenation, halogen atoms are introduced at specific positions of the alkynyl group to obtain halogenated alkynyl alcohol derivatives. After deprotecting the group, it reacts with cyanate to form an intermediate of isoferocyanate. After reacting with benzylating reagents, benzyl group introduction is achieved, and the target product 1-alkynyl-4-isoferocyanate is obtained.
There is another method 3, which takes metal catalytic coupling reaction as the path. Take alkynyl boric acid or borate ester, with halobenzyl and isoferric acid sources, under the catalysis of metal catalysts such as palladium and copper, in a system with suitable ligands and bases, through multi-step coupling reaction, one-step or step-by-step construction of carbon-carbon and carbon-nitrogen bonds to form 1-alkynyl-4-benzyl isoferocyanate. These various methods have their own advantages and disadvantages. According to the availability of raw materials, the difficulty of reaction, the high or low yield, etc., carefully weigh and choose the good one.